Coro1b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose intron excision ratio chr1:201443113:201443758 0.03 0.03 4.2e-03 0.01 0.01 0.01 0 3.6e-02 2.3e-02 5.0e-02 1.0e-01
2 Adipose intron excision ratio chr1:201443127:201443758 0.03 0.02 9.5e-03 0.01 0.01 0.01 0.01 1.9e-02 2.7e-02 6.6e-02 4.6e-02
3 BLA intron excision ratio chr1:201443113:201443758 0.22 0.12 1.9e-07 0.14 0.15 0.14 0.14 7.0e-08 1.3e-08 5.4e-08 4.5e-08
4 BLA intron excision ratio chr1:201443127:201443758 0.14 0.09 1.6e-04 0.06 0.07 0.06 0.06 2.6e-04 1.7e-04 3.4e-04 2.2e-04
5 Brain gene expression ENSRNOG00000021828 0.09 0.06 6.4e-04 0.02 0.04 0.03 0.03 6.4e-03 2.7e-04 1.0e-03 7.0e-04
6 Brain intron excision ratio chr1:201443113:201443758 0.2 0.1 4.1e-11 0.12 0.11 0.12 0.12 1.7e-11 2.2e-10 1.5e-11 1.9e-11
7 Brain intron excision ratio chr1:201443127:201443758 0.33 0.25 2.3e-11 0.13 0.13 0.12 0.12 8.3e-12 2.9e-12 4.7e-11 6.2e-11
8 Liver gene expression ENSRNOG00000021828 0.07 0.05 6.4e-04 0.03 0.03 0.04 0.03 1.6e-04 8.1e-04 7.9e-05 1.5e-04
9 Liver intron excision ratio chr1:201443127:201443758 0.08 0.05 3.8e-05 0.05 0.04 0.04 0.04 5.9e-06 3.8e-05 1.5e-05 1.2e-05
10 NAcc intron excision ratio chr1:201443113:201443758 0.07 0.06 6.7e-03 0.04 0.01 0.02 0.03 9.5e-04 1.1e-01 5.8e-03 3.0e-03
11 OFC intron excision ratio chr1:201443120:201443758 0.23 0.16 6.1e-03 0.04 0.03 0.06 0.07 3.2e-02 8.2e-02 1.7e-02 1.0e-02
12 PL intron excision ratio chr1:201443113:201443758 0.05 0.04 2.2e-03 0.02 0.02 0.03 0.02 1.1e-02 5.5e-03 4.8e-03 9.4e-03
13 PL intron excision ratio chr1:201443127:201443758 0.11 0.07 9.7e-06 0.06 0.06 0.05 0.06 4.3e-05 2.4e-05 1.0e-04 1.5e-05
14 PL mRNA stability ENSRNOG00000021828 0.03 0.03 5.9e-03 0.02 0.01 0.02 0.01 1.3e-02 2.3e-02 1.2e-02 5.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail3.511.516.22.8-3.93.7-3.7-3.83.4-3.6-4.0-3.93.6-2.92.5-3.4-0.6
BMI without tail1.83.75.11.6-2.02.2-2.2-2.21.9-2.1-2.1-2.02.0-1.71.6-1.9-0.4
Body weight1.56.217.90.8-2.42.7-2.7-3.81.9-2.4-4.2-2.42.1-1.0-0.0-2.0-3.0
Epididymis fat weight0.81.86.60.10.7-1.31.32.4-0.71.12.40.7-0.7-0.00.70.82.6
Glucose1.01.55.11.7-0.90.7-0.70.31.1-0.80.6-0.91.1-1.62.0-1.12.3
Heart weight0.30.42.30.30.1-0.50.51.1-0.10.31.10.1-0.1-0.30.30.11.5
Left kidney weight0.72.14.2-1.11.1-1.81.82.1-1.51.61.71.1-1.31.1-1.21.60.9
Right kidney weight1.13.04.5-1.61.4-2.12.12.1-1.92.01.61.4-1.71.6-1.72.00.4
Tail length0.51.64.3-1.71.4-0.80.8-0.2-1.10.8-0.01.4-1.21.5-2.01.1-2.1
Length with tail0.52.011.9-1.40.30.3-0.2-1.7-0.5-0.0-1.90.3-0.41.2-2.20.5-3.4
Length without tail0.61.46.0-0.5-0.70.8-0.8-1.80.3-0.6-2.2-0.70.40.3-1.2-0.3-2.4
Liver weight, left0.10.20.7-0.10.7-0.30.30.4-0.30.30.80.7-0.50.10.20.30.3
Liver weight, right0.40.60.8-0.80.8-0.90.90.7-0.80.80.60.8-0.80.9-0.70.8-0.2
Parametrial fat weight0.40.84.61.1-0.60.1-0.10.90.6-0.20.8-0.60.6-1.11.1-0.52.1
Retroperitoneal fat weight1.44.715.40.11.5-2.12.13.7-1.11.73.91.5-1.30.01.01.33.8
Intraocular pressure1.52.12.7-1.41.5-1.61.61.4-1.61.61.31.5-1.61.4-1.11.6-0.2
Extensor digitorum longus weight1.66.225.3-0.6-1.52.1-2.1-4.10.9-1.6-4.8-1.51.60.5-0.7-1.0-5.0
Soleus weight2.46.914.9-1.52.5-3.13.13.9-2.42.83.82.5-2.41.6-0.92.52.2
Tibialis anterior weight1.96.439.0-2.60.00.5-0.5-3.1-1.00.1-4.30.00.22.5-2.70.8-6.2
Tibia length0.61.84.6-1.71.2-1.21.20.6-1.51.30.31.2-1.11.6-2.11.5-1.3
Number of licking bursts0.10.10.20.4-0.30.4-0.4-0.30.4-0.3-0.2-0.30.3-0.40.2-0.40.1
Food consumed during 24 hour testing period0.50.60.7-0.60.8-0.80.80.8-0.80.80.80.8-0.80.6-0.60.80.2
Times rat made contact with spout0.80.91.20.8-1.01.1-1.1-1.11.0-1.1-1.1-1.01.0-0.90.6-1.0-0.2
Mean time between licks in bursts0.20.31.1-0.2-0.20.4-0.4-0.80.1-0.3-0.9-0.20.20.2-0.5-0.2-1.0
Mean num. licks in bursts0.10.10.20.3-0.40.3-0.3-0.20.3-0.4-0.3-0.40.4-0.30.3-0.30.1
Std. dev. time between licks in bursts0.91.13.1-1.40.9-0.80.80.1-1.00.9-0.10.9-1.01.4-1.71.0-1.4
Water consumed over 24 hours0.60.71.20.6-0.81.0-1.0-1.10.8-0.9-1.1-0.80.7-0.70.6-0.8-0.5
Indifference point 0 sec0.10.10.80.1-0.3-0.30.30.6-0.10.10.4-0.30.1-0.1-0.10.10.9
Indifference point AUC0.50.63.1-0.6-0.40.1-0.1-0.8-0.30.1-1.6-0.4-0.00.6-0.60.2-1.8
Indifference point function ln k1.72.48.8-0.21.6-1.51.52.3-0.91.23.01.6-1.10.30.11.02.3
Indifference point function log k1.72.48.8-0.21.6-1.51.52.3-0.91.23.01.6-1.10.30.11.02.3
Delay discounting total patch changes 0 sec0.10.20.6-0.40.1-0.60.60.7-0.50.50.30.1-0.30.3-0.80.50.3
Delay discounting total patch changes 12 sec0.91.25.3-0.0-1.20.9-0.9-1.50.5-0.7-2.3-1.20.7-0.0-0.5-0.6-1.7
Delay discounting total patch changes 18 sec0.30.41.40.3-1.00.5-0.5-0.60.3-0.4-1.2-1.00.6-0.3-0.2-0.3-0.4
Delay discounting total patch changes 24 sec0.30.31.9-0.60.0-0.10.1-0.5-0.40.2-0.90.0-0.20.6-0.70.3-1.4
Delay discounting total patch changes 6 sec0.91.32.70.8-1.51.2-1.2-1.31.0-1.2-1.6-1.51.3-0.90.0-1.1-0.4
Delay discounting time to switch 0 sec3.35.06.92.2-2.22.6-2.6-2.42.5-2.5-2.0-2.22.3-2.21.9-2.4-0.0
Delay discounting water rate 0 sec5.68.913.1-2.62.9-3.53.53.6-3.23.33.22.9-3.02.6-2.23.20.7
Delay discounting water rate 12 sec7.110.716.1-2.73.4-3.83.84.0-3.33.63.83.4-3.32.7-2.23.41.0
Delay discounting water rate 18 sec1.21.62.9-0.81.3-1.51.51.7-1.21.31.71.3-1.40.9-0.21.20.7
Delay discounting water rate 24 sec3.95.37.1-2.12.3-2.62.72.6-2.52.52.42.3-2.52.1-1.72.50.3
Delay discounting water rate 6 sec3.14.65.9-2.02.4-2.42.42.2-2.32.32.22.4-2.41.9-1.52.3-0.1
Locomotor activity0.91.52.9-0.91.4-1.31.31.4-1.11.11.71.4-1.10.8-1.31.00.6
Locomotor testing distance1.01.63.4-0.91.5-1.41.41.6-1.11.21.81.5-1.20.8-1.01.10.7
Locomotor testing rearing0.20.41.70.60.2-0.10.10.60.2-0.11.10.20.1-0.51.1-0.31.3
Light reinforcement 10.40.81.8-0.60.8-1.11.11.3-1.01.11.00.8-0.90.6-0.21.00.5
Light reinforcement 21.31.74.2-0.71.0-1.61.62.1-1.21.51.71.0-1.10.8-0.41.21.2
Reaction time number correct0.40.62.0-1.00.6-0.50.5-0.1-0.70.7-0.40.6-0.60.9-1.40.7-1.3
Reaction time mean minus median1.41.83.60.8-1.51.5-1.5-1.91.2-1.5-1.7-1.51.4-0.8-0.0-1.3-0.6
Reaction time mean minus median AUC0.50.61.90.1-0.70.8-0.8-1.40.5-0.8-1.2-0.70.7-0.0-0.8-0.5-1.0
Reaction time num false alarms0.81.12.4-1.21.1-1.01.00.6-1.21.00.61.1-1.01.2-1.51.1-0.8
Reaction time num false alarms AUC0.50.62.3-1.00.7-0.50.5-0.1-0.70.5-0.20.7-0.61.0-1.50.7-1.3
Reaction time trials correct on left0.40.62.0-1.00.6-0.50.5-0.1-0.70.7-0.40.6-0.60.9-1.40.7-1.3
Reaction time trials on left0.50.72.4-1.10.6-0.50.5-0.1-0.80.7-0.50.6-0.71.0-1.60.7-1.4
Reaction time mean0.30.50.70.9-0.60.7-0.7-0.50.7-0.8-0.0-0.60.8-0.80.6-0.70.7
Reaction time mean AUC0.40.60.90.9-0.70.8-0.8-0.50.8-0.80.0-0.70.8-0.80.6-0.80.9
Median of all reaction times0.40.61.01.0-0.60.7-0.7-0.30.8-0.70.1-0.60.8-0.90.9-0.71.0
Reaction time omissions0.50.72.3-0.2-0.70.7-0.7-1.40.4-0.6-1.5-0.70.60.1-1.0-0.5-1.3
Reaction time false alarm rate0.20.30.6-0.70.6-0.50.50.2-0.60.40.30.6-0.50.6-0.80.6-0.5
Reaction time premature initiation rate0.60.82.8-0.1-0.40.9-0.9-1.60.5-0.7-1.5-0.40.60.1-0.8-0.6-1.7
Reaction time premature initiations0.91.26.5-0.8-0.00.5-0.5-1.70.0-0.3-1.8-0.00.10.8-1.7-0.1-2.6
Std. dev. reaction times0.50.71.20.6-1.01.0-1.0-1.10.8-1.0-0.7-1.01.0-0.6-0.2-0.90.0
Reaction time trials completed0.50.72.4-1.10.6-0.50.5-0.1-0.80.7-0.50.6-0.71.0-1.60.7-1.4
Reaction time trials AUC0.40.51.9-0.90.5-0.40.4-0.1-0.70.6-0.40.5-0.60.8-1.40.6-1.2
Social response proportion1.21.32.00.8-1.31.2-1.2-1.41.3-1.2-1.4-1.31.4-0.8-0.1-1.2-0.2
Social responses0.30.31.6-0.4-0.30.1-0.1-0.60.1-0.0-1.0-0.30.30.4-1.3-0.1-0.9
Social time0.40.51.70.2-0.80.7-0.7-1.00.5-0.6-1.3-0.80.7-0.2-0.4-0.5-0.8
Conditioned locomotion1.31.65.5-1.71.0-0.60.6-0.4-1.10.9-0.61.0-1.11.6-1.81.1-2.4
Cocaine response after cond. corrected0.00.00.20.20.0-0.00.00.20.1-0.00.30.00.0-0.20.4-0.10.4
Cocaine response after cond. not corrected0.30.30.70.7-0.50.4-0.4-0.10.5-0.50.0-0.50.5-0.70.8-0.50.7
Cocaine response before conditioning0.30.30.50.5-0.70.6-0.6-0.50.6-0.6-0.5-0.70.7-0.50.3-0.60.2
Saline control response0.91.23.70.2-0.91.2-1.2-1.80.7-1.0-1.9-0.90.7-0.30.4-0.8-1.6
Condit. Reinf. active minus inactive responses1.01.32.61.4-1.10.9-0.8-0.21.2-1.00.0-1.11.2-1.41.3-1.21.6
Condit. Reinf. active-inactive response ratio0.50.53.20.9-0.30.0-0.00.70.5-0.20.9-0.30.4-0.81.0-0.41.8
Condit. Reinf. active responses1.72.43.21.8-1.71.5-1.5-0.91.7-1.6-0.7-1.71.7-1.71.7-1.71.3
Condit. Reinf. inactive responses1.62.02.41.2-1.51.6-1.6-1.51.5-1.5-1.5-1.51.5-1.31.2-1.5-0.1
Condit. Reinf. lever presses1.21.72.21.2-1.41.5-1.5-1.51.3-1.4-1.4-1.41.3-1.21.2-1.4-0.2
Condit. Reinf. lever reinforcers received1.92.63.31.8-1.81.6-1.6-1.11.8-1.7-1.0-1.81.8-1.81.7-1.81.0
Pavlov. Cond. lever latency0.00.00.1-0.20.2-0.30.30.3-0.20.30.20.2-0.20.20.00.20.0
Pavlov. Cond. magazine entry latency2.93.45.51.4-1.92.1-2.1-2.41.8-2.0-2.3-1.91.8-1.51.3-1.8-0.9
Pavlov. Cond. change in total contacts0.81.11.61.1-1.11.2-1.2-1.01.1-1.2-0.9-1.11.0-1.11.3-1.10.1
Pavlov. Cond. index score0.91.21.70.9-1.01.3-1.3-1.31.0-1.2-1.3-1.01.0-1.01.0-1.1-0.4
Pavlov. Cond. latency score0.70.91.30.8-0.91.1-1.1-1.10.9-1.0-1.1-0.90.8-0.80.9-0.9-0.4
Pavlov. Cond. lever contacts0.00.10.2-0.30.2-0.20.20.0-0.30.2-0.00.2-0.20.3-0.50.2-0.3
Pavlov. Cond. magazine entry number3.64.57.5-1.62.2-2.52.52.7-2.12.32.72.2-2.11.6-1.22.11.0
Pavlov. Cond. intertrial magazine entries0.81.12.6-0.51.0-1.21.21.5-0.91.11.61.0-0.90.5-0.50.91.0
Pavlov. Cond. lever-magazine prob. diff.1.11.42.30.9-1.21.4-1.4-1.51.1-1.3-1.5-1.21.1-1.01.0-1.2-0.6
Pavlov. Cond. response bias0.50.71.20.6-0.91.0-1.0-1.10.8-0.9-1.1-0.90.8-0.60.3-0.8-0.5
Conditioned reinforcement - actives0.60.60.8-0.70.7-0.90.90.9-0.70.90.70.7-0.80.8-0.30.70.1
Conditioned reinforcement - inactives1.82.06.4-0.10.9-1.41.42.3-0.71.22.50.9-0.90.30.80.82.5
Conditioned locomotion5.16.113.3-1.42.3-2.92.93.6-2.12.73.62.3-2.31.6-0.62.22.2
Intermittent access intake day 1-15 change1.41.43.2-0.71.5-1.31.31.6-0.91.31.81.5-1.10.7-0.51.00.7
Intermittent access intake escalation0.80.82.4-0.31.1-0.90.91.3-0.50.81.61.1-0.70.3-0.20.60.9
Intermittent access intake escalation 20.80.81.9-0.51.1-0.90.91.0-0.60.91.41.1-0.80.5-0.70.70.6
Intermitt. access day 1 inactive lever presses0.40.42.10.20.0-0.50.61.1-0.20.31.00.00.1-0.10.80.21.4
Intermitt. access day 15 inactive lever presses0.60.73.30.60.2-0.30.31.00.20.11.50.20.1-0.51.5-0.01.8
Intermitt. access escalation Index1.11.02.9-0.60.7-1.31.31.7-1.11.21.10.7-0.40.6-0.21.10.9
Intermittent access day 1 total infusions2.73.010.12.4-1.41.1-1.10.31.6-1.31.0-1.41.0-2.12.8-1.53.2
Intermittent access day 15 total infusions1.82.010.91.00.5-0.70.72.00.00.42.70.5-0.4-0.71.40.13.3
Intermittent access terminal intake (last 3 days)1.41.69.21.3-0.1-0.10.11.40.5-0.12.0-0.10.0-1.11.8-0.43.0
Intermittent access total infusions1.31.46.91.5-0.70.3-0.30.80.8-0.51.2-0.70.6-1.22.0-0.72.6
Intermittent access day 1 locomotion2.72.77.12.0-1.81.2-1.2-0.31.6-1.4-0.2-1.81.6-1.72.7-1.62.2
Intermittent access day 15 total locomotion0.91.05.60.70.1-0.50.51.50.00.41.70.1-0.1-0.51.40.02.4
Intermittent access total locomotion1.92.210.71.8-0.80.3-0.31.10.9-0.51.4-0.81.1-1.52.6-0.93.3
Intermittent access standard deviation0.40.41.5-0.10.7-0.60.60.9-0.30.61.20.7-0.50.2-0.10.40.8
Cocaine induced anxiety0.00.10.2-0.10.4-0.10.10.1-0.10.10.50.4-0.40.00.00.10.1
Post-drug Anxiety0.40.41.8-0.80.6-0.20.2-0.4-0.40.2-0.30.6-0.50.7-1.00.5-1.3
Baseline Anxiety0.50.52.9-0.70.10.1-0.1-0.8-0.20.0-1.10.10.00.6-1.10.2-1.7
Lifetime Intake1.21.36.11.5-0.80.4-0.40.60.9-0.61.0-0.80.7-1.21.8-0.82.5
Incentive Sensitization - Responses0.10.10.60.20.1-0.00.10.30.2-0.00.50.10.6-0.20.3-0.10.7
Incentive Sensitization - Breakpoint0.10.10.80.20.2-0.20.20.50.10.10.70.20.5-0.10.2-0.00.9
Progressive ratio test 1 active lever presses0.50.51.8-0.10.3-0.80.81.2-0.50.71.10.3-0.30.3-0.10.51.3
Progressive ratio test 1 breakpoint0.50.51.6-0.30.4-0.90.91.3-0.60.81.00.4-0.40.4-0.10.61.2
Progressive ratio test 1 inactive lever presses0.20.21.00.3-0.6-0.10.10.40.10.00.1-0.60.3-0.10.7-0.21.0
Progressive ratio test 2 active lever presses0.70.83.80.20.4-0.80.81.5-0.30.61.50.40.20.00.30.32.0
Progressive ratio test 2 breakpoint1.31.44.0-0.30.9-1.41.42.0-0.91.22.00.9-0.30.5-0.20.91.9
Progressive ratio test 2 inactive lever presses1.71.911.50.80.2-0.80.82.1-0.10.52.30.20.3-0.61.70.13.4
Total sessions with >9 infusions0.30.31.30.6-0.40.1-0.10.40.4-0.20.4-0.40.3-0.41.1-0.41.1
Short access day 1 total inactive lever presses0.60.73.70.3-0.0-0.70.71.4-0.20.41.3-0.0-0.3-0.20.80.31.9
Short access day 10 total inactive lever presses0.40.41.70.30.3-0.40.40.9-0.10.21.30.3-0.3-0.30.80.21.3
Short access day 1 total infusions0.80.94.51.2-0.60.2-0.20.60.6-0.50.9-0.60.7-1.01.5-0.72.1
Short access day 10 total infusions3.03.35.72.3-1.91.6-1.6-0.71.9-1.8-0.2-1.91.6-2.12.4-1.92.1
Short access total infusions1.21.32.81.4-1.20.8-0.8-0.21.2-1.00.0-1.20.9-1.21.5-1.21.7
Short access day 1 locomotion1.01.13.71.2-0.90.4-0.40.30.8-0.60.2-0.91.2-1.01.9-0.81.8
Short access day 10 total locomotion0.80.92.31.1-1.00.6-0.6-0.00.8-0.7-0.1-1.01.3-0.91.5-0.91.3
Short access total locomotion1.11.12.51.1-1.30.6-0.6-0.10.9-0.7-0.5-1.31.5-0.91.6-1.01.3
Compulsive drug intake0.90.95.6-1.0-0.10.1-0.1-1.2-0.3-0.1-1.6-0.1-0.10.9-0.90.2-2.4
One hour access (0.3 mA shock)1.92.39.60.40.8-1.31.32.5-0.61.02.90.8-0.7-0.10.80.63.1
One hour access (shock baseline)2.32.610.90.30.9-1.51.52.8-0.81.23.00.9-0.6-0.10.40.83.3
Number of responses in last shaping day0.20.20.5-0.30.1-0.60.60.7-0.40.60.50.1-0.20.4-0.30.30.7
Context. condit. distance diff. score0.20.21.30.40.1-0.20.20.70.00.20.70.10.0-0.40.60.01.1
Locomotion velocity, session 10.00.00.00.1-0.10.1-0.1-0.10.1-0.1-0.1-0.10.1-0.1-0.1-0.00.0
Locomotion distance, session 12.12.83.31.7-1.81.8-1.8-1.51.8-1.7-1.5-1.81.8-1.71.8-1.80.3
Locomotion velocity, session 20.70.82.70.0-0.70.9-0.9-1.50.5-0.7-1.6-0.70.6-0.0-0.2-0.6-1.5
Locomotion distance, session 21.01.52.31.0-1.31.4-1.4-1.51.2-1.3-1.5-1.31.2-0.91.1-1.2-0.4
Locomotion velocity, session 31.82.02.71.6-1.61.4-1.4-1.01.6-1.5-0.9-1.61.6-1.61.4-1.60.9
Locomotion distance, session 30.20.20.30.4-0.50.4-0.4-0.30.5-0.4-0.3-0.50.5-0.40.3-0.50.3
Stereotopy head waving bouts, day 31.11.33.51.5-1.01.0-1.0-0.41.2-1.2-0.1-1.01.1-1.51.9-1.21.1
Stereotopy head waving duration, day 30.50.62.01.0-0.40.3-0.30.40.5-0.50.6-0.40.4-1.01.4-0.51.4
Locomotion velocity, session 71.31.41.91.3-1.31.2-1.2-0.81.3-1.2-0.8-1.31.4-1.31.4-1.30.8
Locomotion distance, session 70.30.40.60.5-0.70.7-0.7-0.80.6-0.7-0.8-0.70.6-0.40.5-0.6-0.2
Stereotopy head waving bouts, day 71.01.12.71.3-1.00.8-0.8-0.11.1-0.90.1-1.01.0-1.31.6-1.11.4
Stereotopy head waving duration, day 72.22.73.31.7-1.81.8-1.8-1.51.8-1.8-1.4-1.81.8-1.71.7-1.80.3
Locomotion velocity, session 80.50.61.80.1-0.60.8-0.8-1.30.5-0.7-1.3-0.60.5-0.20.0-0.5-1.2
Locomotion distance, session 80.20.30.90.7-0.50.4-0.4-0.00.5-0.4-0.0-0.50.5-0.70.9-0.50.7
Degree of sensitization distance0.50.50.80.6-0.70.8-0.8-0.80.7-0.8-0.7-0.70.7-0.60.9-0.7-0.1
Degree of sensitization stereotypy0.80.91.21.0-1.01.0-1.0-0.81.0-1.0-0.8-1.01.1-1.01.0-1.10.3
Condit. Reinf. active minus inactive responses0.60.71.00.8-0.90.8-0.8-0.70.9-0.8-0.7-0.90.9-0.81.0-0.90.3
Condit. Reinf. active-inactive response ratio0.30.30.50.6-0.70.5-0.5-0.30.6-0.5-0.3-0.70.7-0.60.5-0.60.6
Condit. Reinf. active responses0.10.10.20.3-0.40.3-0.3-0.20.4-0.3-0.2-0.40.4-0.20.4-0.30.2
Condit. Reinf. inactive responses0.10.10.1-0.30.2-0.30.30.3-0.20.30.20.2-0.20.3-0.30.30.1
Incentive salience index mean0.50.60.80.7-0.80.8-0.8-0.70.8-0.7-0.7-0.80.8-0.60.9-0.80.1
Condit. Reinf. lever presses0.00.00.1-0.20.1-0.00.0-0.1-0.00.1-0.20.1-0.10.20.10.1-0.3
Time in familiar zone, hab. session 10.20.20.90.6-0.40.2-0.20.20.4-0.20.3-0.40.4-0.50.4-0.30.9
Time in novel zone, hab. session 10.00.00.1-0.30.2-0.20.20.0-0.20.2-0.00.2-0.20.3-0.10.2-0.3
Total zone transitions, hab. session 10.40.50.90.4-0.70.8-0.8-0.90.7-0.7-0.9-0.70.7-0.40.8-0.7-0.4
Total locomotion distance, hab. session 10.10.21.20.4-0.1-0.00.00.40.10.00.6-0.10.1-0.31.1-0.10.9
Locomotion velocity, hab. session 10.10.10.90.2-0.00.0-0.00.20.00.00.3-0.00.0-0.21.0-0.10.4
Time in familiar zone, hab. session 20.50.51.5-0.90.6-0.40.4-0.1-0.70.5-0.30.6-0.60.8-1.20.7-1.2
Time in novel zone, hab. session 21.21.22.11.3-1.21.0-1.0-0.51.3-1.1-0.4-1.21.2-1.31.4-1.21.0
Total zone transitions, hab. session 25.06.57.82.5-2.72.8-2.8-2.52.7-2.7-2.3-2.72.7-2.52.5-2.70.3
Total locomotion distance, hab. session 21.52.03.91.6-1.41.4-1.4-0.91.4-1.4-0.7-1.41.4-1.62.0-1.50.9
Locomotion velocity, hab. session 21.21.63.81.6-1.31.2-1.2-0.61.3-1.2-0.4-1.31.3-1.52.0-1.31.1
Novel to familiar place preference ratio0.60.60.80.8-0.90.9-0.9-0.70.9-0.8-0.6-0.90.8-0.80.7-0.90.3
Novelty place preference0.60.60.80.9-0.80.8-0.8-0.50.8-0.8-0.3-0.80.8-0.80.8-0.80.6
Time in novel zone, NPP test0.60.60.80.9-0.80.8-0.8-0.50.8-0.8-0.4-0.80.9-0.90.8-0.90.6
Total zone transitions, NPP test1.72.53.31.3-1.61.8-1.8-1.81.6-1.6-1.8-1.61.5-1.31.8-1.6-0.4
Total locomotion distance, NPP test0.40.62.30.9-0.70.7-0.7-0.40.7-0.7-0.4-0.70.7-0.81.5-0.80.5
Locomotion velocity, NPP test0.30.41.70.7-0.50.5-0.5-0.30.5-0.5-0.2-0.50.5-0.61.3-0.60.4
Pavlov. Cond. lever latency0.30.31.5-0.40.4-0.60.60.6-0.60.50.70.4-0.40.4-1.20.50.4
Pavlov. Cond. magazine entry latency1.11.42.11.4-1.21.1-1.1-0.61.4-1.2-0.6-1.21.3-1.41.4-1.30.9
Pavlov. Cond. change in total contacts0.40.42.00.8-0.50.4-0.40.10.6-0.40.2-0.50.6-0.71.4-0.61.0
Pavlov. Cond. index score0.00.00.50.2-0.00.1-0.10.10.2-0.00.0-0.00.0-0.20.7-0.20.2
Pavlov. Cond. latency score0.10.21.10.4-0.30.3-0.3-0.10.4-0.3-0.1-0.30.3-0.41.1-0.40.2
Pavlov. Cond. lever contacts0.20.21.30.4-0.30.4-0.4-0.30.4-0.3-0.4-0.30.3-0.31.2-0.4-0.1
Pavlov. Cond. magazine entry number0.00.00.10.1-0.20.2-0.2-0.30.1-0.3-0.3-0.20.2-0.1-0.2-0.1-0.1
Pavlov. Cond. intertrial magazine entries0.81.01.2-1.01.1-1.11.10.9-1.11.00.91.1-1.11.0-0.91.1-0.1
Pavlov. Cond. lever-magazine prob. diff.0.00.00.30.2-0.10.2-0.2-0.10.3-0.1-0.1-0.10.1-0.20.6-0.20.1
Pavlov. Cond. response bias0.00.00.20.2-0.00.0-0.00.10.20.00.0-0.00.1-0.10.5-0.10.2
Bone: apparent density2.64.36.52.5-1.92.4-2.4-1.92.5-2.5-1.0-1.91.6-2.51.9-2.50.8
Bone surface3.96.89.22.4-2.63.0-3.0-2.92.8-2.9-2.6-2.62.6-2.52.1-2.8-0.4
Bone volume2.44.05.32.2-2.02.3-2.3-1.92.3-2.3-1.4-2.01.8-2.31.8-2.30.5
Bone: connectivity density3.96.29.12.5-2.23.0-3.0-2.92.8-3.0-2.0-2.22.1-2.61.8-2.8-0.2
Bone: cortical apparent density0.10.10.9-0.3-0.00.2-0.2-0.6-0.1-0.1-0.7-0.00.00.3-0.30.1-1.0
Bone: cortical area0.30.51.7-0.90.6-0.40.4-0.1-0.70.5-0.30.6-0.70.8-0.90.7-1.3
Bone: cortical porosity0.10.10.40.3-0.60.3-0.3-0.20.3-0.3-0.5-0.60.6-0.3-0.0-0.30.1
Bone: cortical porosity0.20.20.80.1-0.60.4-0.4-0.50.3-0.3-0.9-0.60.5-0.1-0.2-0.3-0.5
Bone: cortical thickness1.52.412.0-2.01.0-0.50.4-1.0-1.30.8-1.31.0-1.11.9-2.11.2-3.5
Bone: cortical thickness0.60.73.6-0.90.60.0-0.0-0.8-0.50.2-0.60.6-0.70.8-1.30.4-1.9
Bone: cortical tissue density0.10.21.1-0.4-0.00.2-0.2-0.6-0.1-0.1-0.7-0.00.10.4-0.30.1-1.1
Bone: elastic displacement3.33.75.0-2.21.9-2.12.11.5-2.22.11.11.9-2.02.1-2.12.2-1.0
Bone: elastic work0.91.24.2-1.50.7-0.60.6-0.3-1.10.7-0.70.7-0.81.3-1.61.0-2.1
Bone: endosteal estimation0.61.35.51.5-1.00.5-0.40.61.0-0.60.5-1.01.1-1.41.6-0.92.3
Bone: endosteal perimeter1.22.511.02.1-1.30.6-0.60.91.3-0.90.9-1.31.3-2.02.2-1.23.3
Bone: final force0.71.12.80.5-0.81.3-1.3-1.70.9-1.1-1.6-0.80.8-0.60.3-0.9-1.3
Bone: final moment0.60.92.30.4-0.71.2-1.2-1.50.8-1.0-1.5-0.70.6-0.60.2-0.8-1.2
Bone: marrow area0.61.35.51.5-1.00.4-0.40.61.0-0.60.5-1.01.0-1.41.6-0.92.3
Bone: maximum diameter0.10.20.4-0.40.3-0.60.60.6-0.50.50.30.3-0.30.4-0.20.50.1
Bone: maximum force2.74.86.31.9-2.32.5-2.5-2.42.2-2.4-2.5-2.32.3-2.01.7-2.2-0.4
Bone: maximum moment2.34.05.41.7-2.22.2-2.2-2.22.0-2.2-2.3-2.22.1-1.81.5-2.0-0.4
Bone: minimum diameter1.22.24.51.9-1.51.1-1.1-0.11.5-1.3-0.1-1.51.5-1.91.8-1.52.1
Bone: periosteal estimation0.00.10.30.3-0.2-0.00.00.30.1-0.00.1-0.20.2-0.30.3-0.10.6
Bone: periosteal perimeter0.20.40.70.8-0.70.4-0.4-0.00.6-0.5-0.1-0.70.6-0.80.8-0.60.8
Bone: post-yield work7.510.214.33.8-3.53.0-3.0-1.73.5-3.2-1.6-3.53.7-3.83.3-3.52.6
Bone: stiffness2.94.76.02.1-2.32.4-2.4-2.22.2-2.3-2.2-2.32.4-2.12.0-2.20.0
Bone: tissue strength0.20.20.70.5-0.60.2-0.20.00.4-0.3-0.3-0.60.5-0.50.9-0.30.4
Bone: trabecular number2.33.65.32.2-1.72.2-2.2-1.72.2-2.2-1.0-1.71.5-2.31.9-2.20.6
Bone: trabecular spacing0.60.71.4-1.10.4-1.11.10.9-1.11.2-0.00.4-0.21.2-0.51.1-0.3
Bone: trabecular thickness1.01.22.51.6-0.51.0-1.0-0.31.3-1.20.8-0.50.3-1.61.0-1.31.6
Bone: trabecular tissue density3.34.69.8-1.32.0-2.62.63.1-2.02.42.92.0-1.61.5-0.72.11.7
Breakpoint value in progressive ratio session0.70.82.20.3-0.61.0-1.1-1.50.6-0.8-1.5-0.60.4-0.40.0-0.6-1.4
Distance traveled before self-admin0.10.10.20.3-0.00.4-0.4-0.40.3-0.3-0.3-0.00.3-0.4-0.0-0.2-0.3
Distance traveled after self-admin0.10.10.30.20.60.2-0.2-0.20.2-0.20.60.60.4-0.3-0.2-0.10.2
Delta time in closed arm before/after self-admin0.30.31.7-0.7-0.1-0.10.1-0.5-0.20.2-1.0-0.1-0.20.7-0.50.2-1.3
Delta time in open arm before/after self-admin0.10.10.40.30.00.1-0.10.20.1-0.10.50.00.0-0.30.1-0.10.7
Diff in mean of infusions in LGA sessions0.20.21.0-0.40.30.0-0.0-0.3-0.30.2-0.40.3-0.50.2-0.60.3-1.0
Extinction: sum of active levers before priming1.91.94.40.7-1.11.6-1.7-2.11.2-1.4-2.1-1.11.1-0.90.6-1.2-1.5
Active lever presses in extinction session 60.70.72.6-1.10.6-0.40.4-0.3-0.70.5-0.60.6-0.51.1-1.50.6-1.6
Delta distance traveled before/after self-admin0.10.10.5-0.10.6-0.10.10.10.00.00.70.6-0.20.1-0.10.10.1
Delta ambulatory time before/after self-admin0.10.10.4-0.20.6-0.10.1-0.10.00.00.50.6-0.00.2-0.30.1-0.1
Time in closed arm before self-admin0.10.10.70.5-0.20.2-0.20.10.2-0.20.3-0.20.5-0.40.2-0.20.8
Time in closed arm after self-admin0.10.10.2-0.4-0.1-0.20.20.0-0.20.2-0.4-0.10.10.5-0.40.2-0.4
Time in open arm before self-admin0.10.10.9-0.40.3-0.00.0-0.3-0.20.1-0.30.3-0.50.3-0.00.2-1.0
Time in open arm after self-admin0.10.10.3-0.30.5-0.20.20.1-0.30.20.40.5-0.60.2-0.40.3-0.2
Sum of active levers in priming session hrs 5-62.82.74.6-2.01.9-1.61.60.8-1.71.60.71.9-1.52.0-2.21.7-1.4
Time to tail flick, vehicle, before self-admin2.22.24.01.8-1.31.7-1.7-1.31.6-1.7-0.7-1.31.1-1.82.0-1.50.5
Time to tail flick, vehicle, after self-admin1.71.85.30.6-1.61.4-1.4-1.81.1-1.3-2.3-1.61.2-0.70.3-1.2-1.2
Time to tail flick, test, before self-admin2.12.13.81.7-1.61.4-1.4-0.91.6-1.5-0.7-1.61.5-1.51.9-1.61.1
Time to tail flick, test, after self-admin0.10.10.4-0.10.30.0-0.0-0.1-0.10.00.00.3-0.20.1-0.70.2-0.3
Delta time to tail flick, vehicle, before/after SA0.70.73.7-0.2-1.10.4-0.4-0.90.2-0.3-1.9-1.10.90.2-0.6-0.4-1.1
Delta time to tail flick, test, before/after SA3.22.97.1-2.01.8-1.41.40.5-1.71.50.61.8-1.81.9-2.71.8-1.8
Ambulatory time before self-admin0.20.20.50.5-0.10.5-0.5-0.40.4-0.4-0.3-0.10.7-0.60.5-0.3-0.1
Ambulatory time after self-admin0.60.61.51.2-0.10.7-0.7-0.10.8-0.80.7-0.10.9-1.20.9-0.71.2
Total heroin consumption1.21.45.2-0.1-1.01.1-1.1-1.90.6-0.8-2.3-1.00.6-0.0-0.7-0.6-2.0
Area under the delay curve1.21.32.11.3-1.51.0-1.0-0.61.1-1.0-0.9-1.51.1-1.21.3-1.10.7
Delay disc. indifference point, 0s delay1.92.13.81.6-1.91.3-1.3-0.81.3-1.3-1.0-1.91.6-1.71.5-1.31.0
Delay disc. indifference point, 16s delay0.30.31.70.5-0.3-0.30.20.9-0.10.20.6-0.30.0-0.41.00.11.3
Delay disc. indifference point, 2s delay0.40.51.70.9-0.80.5-0.5-0.00.6-0.5-0.1-0.80.5-0.81.3-0.60.8
Delay disc. indifference point, 24s delay0.20.20.4-0.60.4-0.40.40.2-0.50.5-0.00.4-0.40.5-0.60.5-0.5
Delay disc. indifference point, 4s delay0.70.71.60.8-1.30.8-0.8-0.60.8-0.7-1.1-1.30.9-0.80.7-0.80.2
Delay disc. indifference point, 8s delay0.60.61.00.8-1.00.8-0.8-0.60.8-0.8-0.7-1.00.8-0.80.7-0.70.2
Delay discount exponential model param0.91.01.6-1.11.3-0.90.90.6-1.00.90.91.3-1.01.1-1.11.0-0.5
Delay discount hyperbolic model param1.01.01.7-1.11.3-1.01.00.6-1.10.90.91.3-1.01.1-1.21.0-0.4
Fecal boli incidents, locomotor time 10.10.10.60.1-0.3-0.00.00.1-0.0-0.1-0.0-0.3-0.1-0.00.80.00.3
Change in fecal boli incidents, locomotor task0.30.30.60.5-0.50.7-0.7-0.70.6-0.7-0.5-0.50.6-0.50.6-0.6-0.1
Time >=10cm from walls, locomotor time 12.02.04.71.9-0.91.1-1.1-0.21.5-1.30.6-0.91.5-1.81.8-1.52.2
Bouts of movement, locomotor time 10.40.51.8-0.90.3-0.30.3-0.3-0.70.5-0.70.3-0.60.8-1.00.7-1.3
Total resting periods, locomotor time 10.40.51.4-0.90.4-0.40.4-0.0-0.70.6-0.30.4-0.60.8-1.20.7-1.0
Rest time, locomotor task time 12.22.43.8-1.21.7-1.61.61.7-1.51.62.01.7-1.51.2-1.91.60.5
Distance moved, locomotor task time 11.31.42.01.3-1.31.2-1.2-0.91.2-1.2-0.9-1.31.2-1.31.4-1.20.6
Vertical activity count, locomotor time 10.40.41.90.7-0.20.0-0.00.60.2-0.20.7-0.20.2-0.71.2-0.21.4
Time >=10cm from walls, locomotor time 20.10.10.2-0.30.2-0.40.40.4-0.30.40.30.2-0.20.3-0.10.30.0
Bouts of movement, locomotor time 20.20.21.1-0.2-0.60.2-0.2-0.50.1-0.1-1.1-0.60.20.2-0.4-0.1-0.8
Total resting periods, locomotor time 20.20.20.90.0-0.70.3-0.3-0.40.2-0.2-0.9-0.70.40.0-0.3-0.1-0.4
Rest time, locomotor task time 20.50.64.00.8-0.1-0.10.10.90.1-0.11.3-0.10.3-0.8-0.1-0.12.0
Distance moved, locomotor task time 20.30.31.7-0.80.3-0.30.3-0.3-0.40.4-0.60.3-0.50.7-0.60.4-1.3
Vertical activity count, locomotor time 21.92.13.5-1.91.5-1.51.50.9-1.61.50.51.5-1.61.7-1.41.5-1.3
Weight adjusted by age0.50.61.90.0-0.60.8-0.8-1.30.4-0.6-1.4-0.60.3-0.10.2-0.6-1.3
Seeking ratio, delayed vs. immediate footshock0.80.92.01.1-0.91.0-1.0-0.71.1-1.1-0.5-0.91.0-1.11.4-1.00.4
Locomotion in novel chamber1.82.29.20.51.1-1.11.02.2-0.40.83.01.1-0.8-0.31.10.52.9
Locomotion in novel chamber post-restriction1.21.44.2-0.20.9-1.31.31.9-0.91.02.10.9-0.90.30.71.01.7
Progressive ratio4.24.97.02.2-2.22.6-2.6-2.42.4-2.7-1.9-2.21.6-2.31.9-2.4-0.0
Food seeking constrained by brief footshock0.10.10.30.2-0.10.4-0.4-0.60.4-0.4-0.3-0.10.3-0.20.6-0.3-0.4
Seeking ratio, punishment vs. effort2.53.14.5-1.81.8-2.12.12.0-2.02.11.51.8-1.41.9-0.92.0-0.0
Run reversals in cocaine runway, females2.72.63.51.5-1.71.9-1.9-1.81.8-1.8-1.6-1.71.5-1.51.6-1.7-0.1
Run reversals in cocaine runway, males1.11.12.1-1.11.3-0.80.80.3-0.80.80.81.3-1.41.1-1.40.9-0.9
Latency to leave start box in cocaine runway1.01.11.81.3-1.01.0-1.1-0.61.2-1.1-0.4-1.01.3-1.31.3-1.10.9
Latency to leave start box in cocaine runway, F0.70.81.21.1-0.80.9-0.9-0.61.0-1.0-0.4-0.80.9-1.11.1-0.90.5
Latency to leave start box in cocaine runway, M0.00.00.10.20.00.1-0.10.00.2-0.10.10.00.4-0.20.1-0.20.2
Cd content in liver0.80.92.1-0.50.7-1.11.11.5-0.71.01.30.7-0.80.6-0.70.80.9
Co content in liver1.21.41.9-1.31.2-1.31.31.1-1.41.30.81.2-1.21.3-1.41.3-0.3
Cu content in liver0.00.10.2-0.3-0.1-0.00.0-0.2-0.20.1-0.4-0.1-0.00.3-0.40.1-0.4
Fe content in liver0.00.00.1-0.00.00.1-0.1-0.20.0-0.1-0.20.00.1-0.0-0.2-0.1-0.3
K content in liver2.72.73.71.4-1.81.8-1.8-1.71.6-1.7-1.9-1.81.7-1.41.6-1.7-0.3
Mg content in liver3.63.75.22.1-2.31.9-1.9-1.22.0-1.9-1.3-2.32.1-2.12.3-2.01.2
Mn content in liver0.70.82.30.3-1.00.9-0.9-1.20.5-0.7-1.5-1.00.7-0.20.9-0.6-1.0
Na content in liver0.40.40.7-0.70.8-0.60.60.3-0.70.70.30.8-0.70.7-0.70.7-0.7
Rb content in liver1.62.04.81.8-1.51.0-1.0-0.11.4-1.20.1-1.51.5-1.81.5-1.42.2
Se content in liver0.60.71.71.1-0.50.7-0.7-0.21.0-0.80.1-0.50.8-1.01.3-0.90.9
Sr content in liver0.70.63.4-1.00.6-0.10.1-0.7-0.60.3-0.60.6-0.60.9-1.10.5-1.9
Zn content in liver0.20.20.9-0.2-0.20.4-0.4-0.80.1-0.3-0.8-0.20.10.2-0.4-0.1-1.0