Cenpc

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000021776 0.07 0.04 1.0e-04 0.04 0.03 0.03 0.04 3.5e-05 3.5e-04 2.4e-04 9.1e-05
2 BLA mRNA stability ENSRNOG00000021776 0.14 0.09 2.5e-03 0.05 0.04 0.04 0.05 1.7e-03 1.8e-03 1.9e-03 1.0e-03
3 Brain gene expression ENSRNOG00000021776 0.07 0.04 4.4e-05 0.05 0.06 0.05 0.06 1.2e-05 3.4e-06 2.5e-05 1.8e-06
4 Brain mRNA stability ENSRNOG00000021776 0.22 0.08 6.9e-10 0.08 0.1 0.1 0.09 5.3e-08 1.5e-09 2.5e-09 5.6e-09
5 Liver gene expression ENSRNOG00000021776 0.08 0.04 7.0e-07 0.03 0.04 0.03 0.03 1.6e-04 7.5e-05 1.8e-04 4.4e-04
6 NAcc mRNA stability ENSRNOG00000021776 0.07 0.04 3.8e-05 0.1 0.07 0.07 0.09 1.0e-07 8.1e-06 1.1e-05 2.5e-07
7 PL alternative polyA ENSRNOT00000031074 0.05 0.04 9.7e-04 0.05 0.03 0.05 0.04 7.5e-05 2.3e-03 2.0e-04 5.3e-04
8 PL alternative polyA ENSRNOT00000113695 0.05 0.03 1.7e-03 0.04 0.03 0.04 0.03 1.1e-03 3.1e-03 1.1e-03 1.6e-03
9 PL alternative polyA ENSRNOT00000031074 0.05 0.03 5.5e-04 0.06 0.03 0.05 0.05 3.1e-05 1.3e-03 7.3e-05 1.9e-04
10 PL alternative polyA ENSRNOT00000113695 0.05 0.03 7.4e-04 0.04 0.03 0.04 0.04 4.8e-04 1.3e-03 2.8e-04 6.9e-04
11 PL isoform ratio ENSRNOT00000113695 0.04 0.03 3.2e-03 0.03 0.01 0.03 0.03 1.5e-03 2.2e-02 2.7e-03 5.1e-03
12 PL mRNA stability ENSRNOG00000021776 0.06 0.03 1.8e-05 0.06 0.06 0.06 0.06 3.3e-05 1.6e-05 3.2e-05 1.8e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail1.24.07.4-1.1-1.9-1.1-2.5-0.2-2.7-2.32.3-2.31.72.3-2.1
BMI without tail0.30.61.6-1.2-0.3-0.9-1.3-0.9-1.0-0.40.4-0.40.10.4-0.4
Body weight0.31.12.8-1.6-0.9-1.4-1.0-1.4-1.7-0.40.4-0.40.90.4-0.6
Epididymis fat weight0.61.33.6-1.8-1.3-1.2-1.5-1.4-1.9-0.00.0-0.00.90.0-0.7
Glucose1.21.83.5-0.10.70.40.9-1.11.01.9-1.91.9-1.2-1.91.4
Heart weight0.60.82.6-0.10.3-0.40.60.30.1-1.31.3-1.31.61.3-0.5
Left kidney weight0.10.40.9-0.9-0.7-0.6-0.9-0.7-1.00.2-0.20.2-0.1-0.2-0.1
Right kidney weight0.41.13.9-2.0-0.1-1.5-0.8-1.9-0.70.8-0.80.8-0.5-0.80.5
Tail length0.00.10.30.2-0.20.4-0.30.10.20.6-0.60.6-0.1-0.6-0.0
Length with tail0.51.93.6-0.01.1-0.01.5-0.81.31.9-1.91.9-0.8-1.91.5
Length without tail0.40.81.4-0.30.6-0.51.2-0.90.61.1-1.11.1-0.3-1.11.0
Liver weight, left1.22.03.9-1.1-0.3-0.7-0.6-1.9-0.82.0-2.02.0-1.2-2.00.8
Liver weight, right1.22.04.7-0.40.20.40.1-1.50.22.2-2.22.2-1.2-2.21.2
Parametrial fat weight1.02.03.6-1.20.5-0.8-0.1-1.90.21.9-1.91.9-1.5-1.91.2
Retroperitoneal fat weight0.82.69.8-3.00.1-2.5-0.7-3.1-0.81.1-1.11.1-0.3-1.10.8
Intraocular pressure0.91.35.1-2.3-0.8-2.2-1.2-1.3-0.9-0.50.5-0.5-0.00.5-0.3
Extensor digitorum longus weight5.220.937.01.8-3.31.2-2.54.4-3.1-6.16.1-6.15.06.1-5.2
Soleus weight0.41.33.71.91.01.51.61.81.5-0.20.2-0.20.30.20.3
Tibialis anterior weight2.17.113.11.4-1.71.3-1.32.9-1.3-3.63.6-3.62.33.6-2.9
Tibia length0.41.22.0-1.21.4-1.40.7-1.11.30.9-0.90.9-1.1-0.91.3
Number of licking bursts0.40.51.5-1.10.7-1.20.6-0.40.6-0.40.4-0.40.90.40.2
Food consumed during 24 hour testing period1.11.33.01.1-0.61.1-1.30.40.01.4-1.41.4-1.7-1.40.3
Times rat made contact with spout0.50.51.9-0.30.6-0.2-0.3-0.40.60.9-0.90.9-1.4-0.90.7
Mean time between licks in bursts1.62.35.1-0.9-0.8-1.0-0.90.5-0.9-2.32.3-2.30.92.3-1.3
Mean num. licks in bursts0.81.03.30.7-0.30.9-0.9-0.0-0.21.2-1.21.2-1.8-1.20.4
Std. dev. time between licks in bursts1.72.04.00.8-2.00.8-1.91.2-1.7-1.31.3-1.30.71.3-1.8
Water consumed over 24 hours1.11.32.6-0.61.2-0.70.0-0.71.11.4-1.41.4-1.6-1.41.2
Indifference point 0 sec0.10.20.40.1-0.40.2-0.5-0.0-0.30.7-0.70.70.6-0.7-0.2
Indifference point AUC3.54.17.10.02.30.22.7-0.72.32.2-2.22.2-2.4-2.22.5
Indifference point function ln k1.11.63.20.0-1.30.3-1.21.0-1.1-1.41.4-1.41.81.4-1.5
Indifference point function log k1.11.63.20.0-1.30.3-1.21.0-1.1-1.41.4-1.41.81.4-1.5
Delay discounting total patch changes 0 sec0.10.20.60.1-0.40.3-0.50.0-0.30.6-0.60.60.8-0.6-0.3
Delay discounting total patch changes 12 sec0.10.10.3-0.00.0-0.1-0.3-0.4-0.00.5-0.50.5-0.5-0.50.1
Delay discounting total patch changes 18 sec0.30.40.80.20.50.50.9-0.10.30.8-0.80.80.5-0.80.4
Delay discounting total patch changes 24 sec0.40.51.10.30.20.60.6-0.00.31.1-1.11.1-0.5-1.10.5
Delay discounting total patch changes 6 sec1.11.73.0-0.51.2-0.80.9-1.10.81.7-1.71.7-1.0-1.71.4
Delay discounting time to switch 0 sec2.23.45.50.0-1.6-0.4-2.40.4-1.9-2.32.3-2.31.72.3-2.3
Delay discounting water rate 0 sec1.01.72.8-0.51.30.31.7-0.71.41.6-1.61.6-0.5-1.61.6
Delay discounting water rate 12 sec0.30.41.60.80.11.30.90.80.50.5-0.50.50.2-0.50.3
Delay discounting water rate 18 sec0.50.61.40.5-0.50.7-0.80.1-0.21.1-1.11.1-1.2-1.10.2
Delay discounting water rate 24 sec0.60.83.71.3-0.21.9-0.20.80.50.9-0.90.9-0.6-0.90.3
Delay discounting water rate 6 sec1.01.44.1-0.51.5-0.02.0-0.91.31.2-1.21.20.2-1.21.5
Locomotor activity0.10.10.7-0.7-0.0-0.8-0.3-0.5-0.00.1-0.10.1-0.3-0.10.2
Locomotor testing distance0.20.30.50.2-0.50.0-0.30.7-0.2-0.60.6-0.60.70.6-0.6
Locomotor testing rearing0.30.41.00.6-0.30.40.00.9-0.2-0.70.7-0.71.00.7-0.5
Light reinforcement 10.10.20.6-0.10.3-0.0-0.5-0.50.50.5-0.50.5-0.8-0.50.4
Light reinforcement 20.20.31.2-1.10.2-0.9-0.1-0.60.1-0.40.4-0.40.20.40.2
Reaction time number correct0.10.20.6-0.5-0.60.1-0.8-0.1-0.7-0.20.2-0.2-0.10.2-0.5
Reaction time mean minus median0.40.61.5-1.1-0.0-1.20.3-0.6-0.7-0.80.8-0.80.80.8-0.3
Reaction time mean minus median AUC0.40.52.1-1.40.1-1.50.3-1.0-0.5-0.50.5-0.50.40.5-0.2
Reaction time num false alarms1.11.56.8-0.42.4-0.62.6-0.41.5-0.10.1-0.11.10.11.3
Reaction time num false alarms AUC1.01.45.9-0.42.2-0.72.4-0.31.2-0.50.5-0.51.50.51.0
Reaction time trials correct on left0.10.20.6-0.5-0.60.1-0.8-0.1-0.7-0.20.2-0.2-0.10.2-0.5
Reaction time trials on left0.10.20.6-0.4-0.70.1-0.80.0-0.7-0.20.2-0.2-0.10.2-0.6
Reaction time mean0.30.40.7-0.3-0.6-0.6-0.70.0-0.8-0.80.8-0.80.20.8-0.7
Reaction time mean AUC0.40.50.8-0.2-0.7-0.5-0.60.2-0.9-0.90.9-0.90.40.9-0.8
Median of all reaction times0.30.40.9-0.0-0.7-0.3-0.90.2-0.8-0.70.7-0.70.20.7-0.8
Reaction time omissions0.50.71.4-0.6-0.2-0.70.10.0-0.6-1.21.2-1.20.71.2-0.7
Reaction time false alarm rate0.91.25.3-0.12.1-0.52.3-0.31.3-0.30.3-0.31.30.31.0
Reaction time premature initiation rate0.50.72.11.50.61.00.91.21.20.2-0.20.2-0.9-0.20.5
Reaction time premature initiations0.30.40.90.90.30.90.60.80.80.3-0.30.3-0.9-0.30.4
Std. dev. reaction times0.30.41.0-0.70.1-1.00.4-0.3-0.5-0.70.7-0.70.60.7-0.2
Reaction time trials completed0.10.20.6-0.4-0.70.1-0.80.0-0.7-0.20.2-0.2-0.10.2-0.6
Reaction time trials AUC0.20.20.6-0.7-0.6-0.2-0.7-0.2-0.8-0.30.3-0.30.10.3-0.5
Social response proportion1.61.73.5-0.60.9-0.10.6-1.10.91.9-1.91.9-1.4-1.91.3
Social responses1.41.92.8-0.01.40.21.4-0.81.41.7-1.71.7-1.4-1.71.7
Social time1.41.83.70.21.70.61.9-0.31.91.3-1.31.3-1.3-1.31.7
Conditioned locomotion1.11.33.41.7-0.91.9-0.71.7-0.3-0.90.9-0.90.80.9-1.2
Cocaine response after cond. corrected0.91.01.7-0.30.8-0.00.7-0.90.81.3-1.31.3-1.3-1.31.1
Cocaine response after cond. not corrected0.50.61.0-0.40.5-0.10.1-0.70.41.0-1.01.0-1.0-1.00.7
Cocaine response before conditioning0.80.92.4-0.1-1.1-0.0-1.50.5-1.3-0.90.9-0.91.00.9-1.3
Saline control response0.30.41.51.20.21.10.40.90.40.3-0.30.30.5-0.3-0.1
Condit. Reinf. active minus inactive responses0.10.10.6-0.20.6-0.10.7-0.00.4-0.10.1-0.10.60.10.3
Condit. Reinf. active-inactive response ratio0.20.30.9-0.9-0.1-0.9-0.0-1.0-0.50.2-0.20.20.3-0.20.2
Condit. Reinf. active responses0.10.20.60.40.30.60.40.70.5-0.20.2-0.20.70.2-0.0
Condit. Reinf. inactive responses0.50.62.41.4-0.31.5-0.61.60.4-0.00.0-0.00.20.0-0.5
Condit. Reinf. lever presses0.10.20.70.60.00.6-0.30.80.70.2-0.20.2-0.3-0.20.1
Condit. Reinf. lever reinforcers received0.20.31.20.90.00.90.11.10.4-0.10.1-0.10.50.1-0.2
Pavlov. Cond. lever latency0.50.72.6-0.51.1-0.71.6-1.20.70.6-0.60.6-0.5-0.61.0
Pavlov. Cond. magazine entry latency0.60.71.2-0.2-1.0-0.2-1.10.7-0.9-1.01.0-1.00.61.0-1.0
Pavlov. Cond. change in total contacts0.81.22.20.7-1.20.7-1.31.5-0.8-1.11.1-1.11.01.1-1.3
Pavlov. Cond. index score1.11.43.00.6-1.60.8-1.71.6-1.0-1.11.1-1.10.41.1-1.4
Pavlov. Cond. latency score1.31.73.40.8-1.51.0-1.51.8-0.9-1.31.3-1.30.71.3-1.5
Pavlov. Cond. lever contacts0.60.83.00.7-1.20.8-1.71.3-0.6-0.40.4-0.40.30.4-1.0
Pavlov. Cond. magazine entry number1.41.73.00.01.7-0.01.6-1.11.51.4-1.41.4-0.8-1.41.6
Pavlov. Cond. intertrial magazine entries1.01.32.1-0.01.40.10.8-0.81.21.3-1.31.3-1.5-1.31.3
Pavlov. Cond. lever-magazine prob. diff.1.11.43.00.8-1.60.9-1.71.7-0.8-1.01.0-1.00.21.0-1.4
Pavlov. Cond. response bias1.11.54.10.7-1.70.7-2.01.6-1.1-0.90.9-0.90.60.9-1.5
Conditioned reinforcement - actives0.20.20.4-0.4-0.20.4-0.00.4-0.0-0.60.6-0.60.30.6-0.3
Conditioned reinforcement - inactives1.61.83.40.31.80.21.7-0.31.81.4-1.41.4-1.0-1.41.7
Conditioned locomotion0.10.20.5-0.6-0.3-0.7-0.4-0.2-0.5-0.30.3-0.30.50.3-0.3
Intermittent access intake day 1-15 change2.22.16.22.2-1.22.5-1.82.5-0.2-0.60.6-0.6-0.30.6-1.4
Intermittent access intake escalation1.91.97.02.3-0.92.6-1.72.3-0.1-0.00.0-0.0-0.70.0-1.0
Intermittent access intake escalation 20.80.83.31.20.21.8-0.81.10.60.7-0.70.7-1.0-0.70.2
Intermitt. access day 1 inactive lever presses2.83.08.73.01.52.51.81.72.01.2-1.21.2-1.1-1.21.1
Intermitt. access day 15 inactive lever presses2.02.23.51.21.40.61.00.01.61.8-1.81.8-1.9-1.81.5
Intermitt. access escalation Index0.70.61.2-0.1-1.10.6-1.00.5-0.9-0.70.7-0.70.50.7-1.0
Intermittent access day 1 total infusions0.30.42.3-0.70.6-1.50.4-1.00.1-0.10.1-0.10.00.10.4
Intermittent access day 15 total infusions0.30.31.11.10.50.5-0.30.60.70.4-0.40.4-0.8-0.40.2
Intermittent access terminal intake (last 3 days)0.30.30.90.90.40.3-0.40.50.60.5-0.50.5-0.9-0.50.2
Intermittent access total infusions0.10.10.70.00.3-0.8-0.2-0.20.20.0-0.00.0-0.3-0.00.1
Intermittent access day 1 locomotion0.20.21.5-0.7-0.1-1.20.1-0.6-0.3-0.20.2-0.20.20.2-0.1
Intermittent access day 15 total locomotion0.10.10.40.60.4-0.20.20.30.3-0.40.4-0.40.40.4-0.1
Intermittent access total locomotion0.20.21.3-0.4-0.1-1.1-0.2-0.4-0.3-0.40.4-0.40.30.4-0.2
Intermittent access standard deviation0.20.20.30.20.50.20.10.10.50.6-0.60.6-0.5-0.60.5
Cocaine induced anxiety0.40.52.0-1.4-0.3-1.0-0.5-0.9-0.5-0.40.4-0.40.80.4-0.3
Post-drug Anxiety0.70.81.5-1.01.2-1.10.8-1.10.90.6-0.60.6-0.7-0.61.1
Baseline Anxiety1.11.23.01.01.10.90.90.51.31.0-1.01.0-1.7-1.01.1
Lifetime Intake0.10.21.0-0.3-0.1-1.0-0.6-0.4-0.2-0.10.1-0.1-0.40.1-0.2
Incentive Sensitization - Responses0.10.10.6-0.20.30.1-0.8-0.30.30.2-0.20.2-0.5-0.20.2
Incentive Sensitization - Breakpoint0.10.10.7-0.10.30.2-0.8-0.20.30.2-0.20.2-0.5-0.20.1
Progressive ratio test 1 active lever presses0.70.72.3-1.1-0.1-1.5-0.4-0.4-0.4-1.01.0-1.00.51.0-0.6
Progressive ratio test 1 breakpoint0.60.61.4-0.8-0.2-1.2-0.4-0.1-0.4-1.01.0-1.00.31.0-0.6
Progressive ratio test 1 inactive lever presses1.51.62.60.71.00.61.0-0.21.41.6-1.61.6-1.6-1.61.3
Progressive ratio test 2 active lever presses0.40.40.9-0.81.0-0.80.1-0.70.80.3-0.30.3-0.8-0.30.7
Progressive ratio test 2 breakpoint0.30.30.9-0.80.9-0.60.2-0.50.80.1-0.10.1-0.8-0.10.6
Progressive ratio test 2 inactive lever presses1.41.63.81.51.70.61.20.41.91.2-1.21.2-1.4-1.21.3
Total sessions with >9 infusions1.11.23.7-0.6-1.5-0.5-1.90.2-1.5-1.01.0-1.00.11.0-1.4
Short access day 1 total inactive lever presses0.80.82.30.50.50.70.10.00.81.2-1.21.2-1.5-1.20.8
Short access day 10 total inactive lever presses0.91.01.41.21.01.21.00.41.11.1-1.11.1-0.5-1.11.0
Short access day 1 total infusions0.50.51.6-1.2-0.8-0.8-1.3-0.7-0.8-0.20.2-0.2-0.50.2-0.5
Short access day 10 total infusions0.60.62.8-0.9-0.4-1.7-0.7-0.8-0.9-0.50.5-0.50.40.5-0.5
Short access total infusions0.90.92.6-0.9-1.2-1.3-1.6-0.5-1.3-0.70.7-0.7-0.20.7-1.0
Short access day 1 locomotion1.31.44.1-1.9-0.9-2.0-0.8-1.3-1.5-0.70.7-0.70.80.7-0.7
Short access day 10 total locomotion0.20.20.6-0.80.5-0.80.5-0.30.5-0.30.3-0.30.20.30.2
Short access total locomotion1.41.44.0-1.8-0.9-2.0-1.0-1.0-1.4-1.01.0-1.00.81.0-0.9
Compulsive drug intake0.60.62.20.30.60.51.50.00.90.7-0.70.7-0.3-0.71.0
One hour access (0.3 mA shock)0.60.72.30.61.5-0.21.10.11.40.6-0.60.6-0.2-0.60.9
One hour access (shock baseline)0.10.20.6-0.50.7-0.80.0-0.40.40.2-0.20.2-0.1-0.20.3
Number of responses in last shaping day0.70.71.30.5-1.10.5-0.90.8-0.7-0.90.9-0.90.10.9-1.2
Context. condit. distance diff. score0.50.61.61.20.90.81.11.11.30.1-0.10.10.0-0.10.4
Locomotion velocity, session 11.11.25.4-2.00.8-2.30.8-1.6-0.1-0.40.4-0.40.80.40.5
Locomotion distance, session 10.40.52.0-0.61.4-0.41.3-0.50.90.0-0.00.00.4-0.00.8
Locomotion velocity, session 20.00.00.10.30.2-0.0-0.10.40.1-0.00.0-0.0-0.00.0-0.1
Locomotion distance, session 20.10.10.4-0.60.5-0.60.3-0.50.20.1-0.10.1-0.1-0.10.3
Locomotion velocity, session 30.40.50.80.10.8-0.80.3-0.30.80.7-0.70.7-0.9-0.70.8
Locomotion distance, session 30.30.40.90.7-0.90.3-0.90.9-0.7-0.30.3-0.3-0.30.3-0.7
Stereotopy head waving bouts, day 30.50.62.5-1.00.5-1.60.4-0.6-0.2-0.60.6-0.61.40.6-0.1
Stereotopy head waving duration, day 31.11.35.7-1.81.5-2.41.0-1.50.50.1-0.10.10.8-0.10.9
Locomotion velocity, session 72.93.15.9-1.82.4-1.92.0-1.91.91.4-1.41.4-0.7-1.42.2
Locomotion distance, session 70.70.91.50.11.1-0.10.9-0.40.91.2-1.21.2-0.9-1.21.2
Stereotopy head waving bouts, day 70.20.20.9-0.60.7-0.61.0-0.30.4-0.10.1-0.10.30.10.6
Stereotopy head waving duration, day 70.20.20.6-0.8-0.0-0.70.2-0.4-0.3-0.40.4-0.40.50.4-0.0
Locomotion velocity, session 80.10.10.40.50.3-0.10.20.60.4-0.20.2-0.2-0.10.20.1
Locomotion distance, session 80.20.31.30.21.1-0.00.90.11.00.4-0.40.40.0-0.40.7
Degree of sensitization distance1.71.73.2-0.01.80.11.8-0.81.61.4-1.41.4-0.7-1.41.6
Degree of sensitization stereotypy0.10.10.30.6-0.20.60.40.50.10.1-0.10.1-0.4-0.10.1
Condit. Reinf. active minus inactive responses0.70.81.50.9-0.40.5-0.11.0-0.7-1.01.0-1.01.21.0-1.0
Condit. Reinf. active-inactive response ratio3.03.25.51.1-1.30.7-0.81.8-1.5-2.22.2-2.22.32.2-2.1
Condit. Reinf. active responses0.10.10.60.40.50.30.80.30.3-0.00.0-0.00.20.00.2
Condit. Reinf. inactive responses1.92.23.4-0.41.6-0.21.3-1.11.71.8-1.81.8-1.6-1.81.8
Incentive salience index mean0.20.31.11.00.30.70.60.90.3-0.30.3-0.30.00.3-0.1
Condit. Reinf. lever presses0.50.62.11.30.21.40.31.21.00.1-0.10.1-1.1-0.10.1
Time in familiar zone, hab. session 10.50.41.51.2-0.10.90.41.20.70.0-0.00.0-1.0-0.00.1
Time in novel zone, hab. session 10.90.92.5-1.6-0.2-1.5-0.6-1.5-1.2-0.30.3-0.31.10.3-0.4
Total zone transitions, hab. session 10.40.61.90.20.90.11.4-0.01.40.4-0.40.4-1.0-0.41.0
Total locomotion distance, hab. session 11.11.54.40.51.60.71.40.12.11.1-1.11.1-1.2-1.11.5
Locomotion velocity, hab. session 11.21.75.10.71.71.21.50.42.31.1-1.11.1-1.1-1.11.4
Time in familiar zone, hab. session 20.20.20.5-0.1-0.00.1-0.20.40.3-0.70.7-0.70.10.7-0.3
Time in novel zone, hab. session 20.50.51.7-1.20.3-1.20.4-1.3-0.50.4-0.40.40.7-0.40.3
Total zone transitions, hab. session 20.81.03.8-0.91.9-1.01.7-0.41.6-0.00.0-0.0-0.20.01.1
Total locomotion distance, hab. session 21.31.75.6-0.92.4-0.42.1-0.62.20.6-0.60.6-0.4-0.61.7
Locomotion velocity, hab. session 21.11.55.0-0.72.2-0.11.9-0.42.20.6-0.60.6-0.5-0.61.6
Novel to familiar place preference ratio0.40.51.1-0.41.0-0.40.8-0.70.80.6-0.60.6-0.4-0.60.9
Novelty place preference0.50.51.4-0.71.2-0.80.9-0.90.80.4-0.40.4-0.3-0.40.9
Time in novel zone, NPP test0.60.71.4-0.81.2-0.90.9-1.00.80.6-0.60.6-0.4-0.61.0
Total zone transitions, NPP test0.50.82.1-1.41.2-1.41.1-1.20.70.2-0.20.20.3-0.20.8
Total locomotion distance, NPP test0.30.41.3-0.71.1-0.21.1-0.40.80.1-0.10.10.3-0.10.6
Locomotion velocity, NPP test0.20.31.2-0.61.00.01.1-0.10.8-0.20.2-0.20.40.20.5
Pavlov. Cond. lever latency0.30.41.1-1.0-0.4-1.0-0.4-0.5-0.8-0.50.5-0.50.90.5-0.3
Pavlov. Cond. magazine entry latency1.21.56.32.5-0.42.40.22.00.50.2-0.20.2-1.3-0.2-0.2
Pavlov. Cond. change in total contacts0.60.62.61.60.21.60.61.30.6-0.20.2-0.2-0.10.2-0.2
Pavlov. Cond. index score0.81.04.32.1-0.22.00.31.50.60.1-0.10.1-1.0-0.1-0.1
Pavlov. Cond. latency score0.70.93.71.90.01.70.41.30.70.3-0.30.3-1.2-0.30.1
Pavlov. Cond. lever contacts0.60.71.41.10.71.10.60.51.10.6-0.60.6-1.2-0.60.6
Pavlov. Cond. magazine entry number0.70.83.5-1.90.2-1.7-0.6-1.6-0.30.3-0.30.30.4-0.30.3
Pavlov. Cond. intertrial magazine entries0.40.51.8-1.00.9-1.40.9-0.80.30.0-0.00.00.5-0.00.5
Pavlov. Cond. lever-magazine prob. diff.0.91.14.62.2-0.22.10.31.60.70.2-0.20.2-1.3-0.2-0.1
Pavlov. Cond. response bias0.60.83.31.7-0.11.80.21.20.60.3-0.30.3-1.1-0.30.0
Bone: apparent density0.30.51.1-0.3-0.2-0.1-0.30.7-0.6-1.01.0-1.00.11.0-0.6
Bone surface0.30.40.7-0.2-0.60.1-0.80.6-0.9-0.70.7-0.70.60.7-0.7
Bone volume0.00.10.4-0.30.3-0.00.20.40.1-0.20.2-0.2-0.60.20.2
Bone: connectivity density0.91.42.5-0.4-0.9-0.1-1.00.6-1.4-1.61.6-1.60.91.6-1.4
Bone: cortical apparent density0.81.13.5-1.51.0-1.31.1-1.90.30.8-0.80.80.1-0.81.0
Bone: cortical area1.31.94.6-2.12.1-1.51.8-1.61.40.5-0.50.50.4-0.51.6
Bone: cortical porosity1.71.93.00.8-1.60.7-1.41.4-1.4-1.41.4-1.41.21.4-1.7
Bone: cortical porosity1.71.92.80.4-1.30.2-1.01.2-1.4-1.71.7-1.71.51.7-1.6
Bone: cortical thickness0.50.81.8-0.60.9-0.11.10.20.6-1.11.1-1.11.41.10.1
Bone: cortical thickness0.50.52.3-0.11.00.41.40.41.5-0.10.1-0.10.30.10.6
Bone: cortical tissue density0.81.03.3-1.40.9-1.30.9-1.80.20.8-0.80.80.1-0.80.9
Bone: elastic displacement0.60.72.11.2-0.21.00.61.50.3-0.90.9-0.90.70.9-0.4
Bone: elastic work0.20.20.50.1-0.30.1-0.10.7-0.4-0.70.7-0.70.10.7-0.3
Bone: endosteal estimation1.22.54.4-1.21.2-1.20.5-1.70.72.1-2.12.1-1.3-2.11.7
Bone: endosteal perimeter0.91.94.9-2.21.3-2.20.4-1.90.51.1-1.11.1-0.5-1.11.4
Bone: final force0.30.51.4-1.21.2-0.70.7-0.70.90.3-0.30.3-0.5-0.30.9
Bone: final moment0.30.62.0-1.41.1-0.80.7-0.90.70.3-0.30.3-0.4-0.30.9
Bone: marrow area1.12.34.2-1.11.1-1.10.4-1.60.62.0-2.02.0-1.2-2.01.6
Bone: maximum diameter1.22.17.3-2.71.5-2.50.9-2.40.40.6-0.60.60.7-0.61.3
Bone: maximum force0.40.61.5-1.21.2-0.70.8-0.70.90.5-0.50.5-0.4-0.51.1
Bone: maximum moment0.50.82.4-1.51.2-1.00.8-1.10.60.6-0.60.6-0.3-0.61.1
Bone: minimum diameter3.26.09.7-2.42.6-1.91.6-3.11.72.8-2.82.8-1.3-2.82.9
Bone: periosteal estimation1.12.33.9-2.01.9-1.71.3-2.01.11.4-1.41.4-0.3-1.41.8
Bone: periosteal perimeter1.62.66.1-2.52.0-2.11.3-2.11.11.2-1.21.2-0.2-1.21.9
Bone: post-yield work0.30.41.8-1.3-0.2-0.8-0.5-1.1-0.60.2-0.20.20.9-0.2-0.2
Bone: stiffness1.11.73.6-1.41.9-1.21.2-1.41.51.1-1.11.1-1.0-1.11.6
Bone: tissue strength0.80.81.5-0.40.7-0.20.5-0.90.41.1-1.11.1-1.2-1.11.1
Bone: trabecular number0.10.20.5-0.30.3-0.00.40.3-0.1-0.70.7-0.70.50.7-0.3
Bone: trabecular spacing0.30.40.9-0.90.8-0.91.0-0.90.50.1-0.10.10.1-0.10.7
Bone: trabecular thickness0.20.21.50.2-0.10.4-0.30.60.20.1-0.10.1-1.2-0.10.1
Bone: trabecular tissue density0.60.83.1-1.50.8-1.80.9-1.20.0-0.40.4-0.40.80.40.5
Breakpoint value in progressive ratio session0.50.51.2-0.21.1-0.30.9-0.61.10.7-0.70.7-0.1-0.71.0
Distance traveled before self-admin0.10.20.5-0.2-0.5-0.6-0.7-0.1-0.7-0.20.2-0.20.10.2-0.3
Distance traveled after self-admin1.21.42.51.50.51.10.90.91.21.2-1.21.2-1.6-1.21.0
Delta time in closed arm before/after self-admin0.60.61.10.9-0.4-0.2-0.20.6-0.6-1.01.0-1.00.41.0-0.7
Delta time in open arm before/after self-admin0.70.71.2-0.90.8-0.8-0.1-1.10.60.9-0.90.9-0.8-0.90.8
Diff in mean of infusions in LGA sessions0.60.71.71.1-1.31.1-1.30.9-0.7-0.20.2-0.20.20.2-0.9
Extinction: sum of active levers before priming0.30.30.7-0.9-0.5-0.8-0.5-0.8-0.50.3-0.30.30.2-0.30.0
Active lever presses in extinction session 60.70.71.1-0.60.9-0.50.5-0.90.81.0-1.01.0-0.6-1.01.0
Delta distance traveled before/after self-admin0.70.81.41.20.31.20.70.71.00.8-0.80.8-1.2-0.80.7
Delta ambulatory time before/after self-admin0.20.30.70.60.10.70.60.60.70.3-0.30.3-0.8-0.30.4
Time in closed arm before self-admin1.61.84.41.11.61.52.10.72.11.1-1.11.1-0.8-1.11.3
Time in closed arm after self-admin2.32.47.72.81.32.41.92.41.9-0.40.4-0.4-0.60.40.5
Time in open arm before self-admin2.83.06.21.3-2.50.6-2.51.3-2.4-1.31.3-1.31.61.3-2.2
Time in open arm after self-admin1.01.13.7-1.4-0.2-1.9-0.9-1.8-0.70.9-0.90.9-0.1-0.90.3
Sum of active levers in priming session hrs 5-60.20.20.50.4-0.10.3-0.4-0.10.30.7-0.70.7-0.7-0.70.2
Time to tail flick, vehicle, before self-admin0.60.61.10.80.80.20.40.10.80.9-0.90.9-1.1-0.90.8
Time to tail flick, vehicle, after self-admin1.41.55.42.31.02.00.61.41.20.8-0.80.8-1.0-0.80.6
Time to tail flick, test, before self-admin0.90.96.72.6-0.41.0-0.31.4-0.2-0.30.3-0.3-0.00.3-0.5
Time to tail flick, test, after self-admin0.60.61.30.20.5-0.00.1-0.30.61.1-1.11.1-0.8-1.10.8
Delta time to tail flick, vehicle, before/after SA0.20.10.50.50.20.7-0.20.10.20.4-0.40.4-0.5-0.40.1
Delta time to tail flick, test, before/after SA1.41.32.7-1.60.9-0.90.6-1.30.81.2-1.21.2-0.9-1.21.2
Ambulatory time before self-admin0.20.20.7-0.7-0.2-0.9-0.5-0.6-0.50.0-0.00.00.3-0.0-0.1
Ambulatory time after self-admin1.31.42.60.41.00.71.20.11.61.3-1.31.3-1.6-1.31.5
Total heroin consumption1.92.23.70.11.8-0.31.2-0.91.81.8-1.81.8-1.3-1.81.9
Area under the delay curve0.30.31.5-1.2-0.3-1.0-0.3-1.00.10.2-0.20.2-0.5-0.20.3
Delay disc. indifference point, 0s delay0.30.41.7-1.3-0.0-1.20.1-0.90.1-0.30.3-0.30.10.30.3
Delay disc. indifference point, 16s delay0.70.72.9-1.7-0.4-1.4-0.6-1.1-0.4-0.40.4-0.40.40.4-0.2
Delay disc. indifference point, 2s delay2.62.96.4-0.21.2-0.21.1-1.11.72.1-2.12.1-2.5-2.12.0
Delay disc. indifference point, 24s delay0.30.31.4-0.3-1.2-0.1-0.7-0.1-0.8-0.20.2-0.20.30.2-0.6
Delay disc. indifference point, 4s delay1.92.04.7-2.21.3-2.01.1-2.11.20.9-0.90.9-0.7-0.91.6
Delay disc. indifference point, 8s delay1.11.11.8-1.1-1.3-0.9-1.3-0.3-1.2-1.11.1-1.10.71.1-1.1
Delay discount exponential model param0.30.41.31.10.10.90.21.0-0.2-0.40.4-0.40.60.4-0.5
Delay discount hyperbolic model param0.60.61.21.1-0.20.9-0.11.1-0.6-0.80.8-0.81.00.8-0.9
Fecal boli incidents, locomotor time 11.51.62.50.8-1.40.7-1.41.3-1.3-1.41.4-1.41.01.4-1.6
Change in fecal boli incidents, locomotor task0.10.10.3-0.2-0.3-0.1-0.0-0.5-0.40.2-0.20.20.5-0.2-0.0
Time >=10cm from walls, locomotor time 10.40.41.9-0.1-0.80.0-0.20.1-0.8-0.60.6-0.61.40.6-0.8
Bouts of movement, locomotor time 10.50.61.2-0.80.7-0.61.1-0.00.7-0.90.9-0.90.60.90.2
Total resting periods, locomotor time 10.40.41.0-1.00.5-0.80.8-0.40.4-0.60.6-0.60.50.60.2
Rest time, locomotor task time 10.40.41.00.90.11.0-0.20.70.40.7-0.70.7-0.9-0.70.1
Distance moved, locomotor task time 10.10.10.3-0.50.2-0.50.5-0.20.3-0.20.2-0.20.30.20.2
Vertical activity count, locomotor time 11.31.44.8-2.10.5-2.10.4-2.20.30.5-0.50.5-0.2-0.50.9
Time >=10cm from walls, locomotor time 20.30.30.70.6-0.40.6-0.10.8-0.2-0.50.5-0.50.80.5-0.4
Bouts of movement, locomotor time 20.60.62.0-0.51.4-0.11.4-0.31.10.5-0.50.5-0.3-0.51.0
Total resting periods, locomotor time 20.60.61.8-0.61.3-0.21.3-0.41.10.5-0.50.5-0.4-0.50.9
Rest time, locomotor task time 20.60.72.91.4-0.61.7-0.41.30.00.3-0.30.3-0.7-0.3-0.4
Distance moved, locomotor task time 21.11.32.6-0.2-0.7-0.6-1.00.4-0.9-1.61.6-1.61.11.6-1.1
Vertical activity count, locomotor time 20.60.72.3-1.3-0.2-1.5-0.9-1.2-0.7-0.50.5-0.50.50.5-0.2
Weight adjusted by age1.61.83.0-0.9-1.50.1-1.00.7-1.4-1.61.6-1.61.71.6-1.4
Seeking ratio, delayed vs. immediate footshock0.60.72.21.21.00.91.50.50.90.5-0.50.50.3-0.50.7
Locomotion in novel chamber0.10.20.30.50.2-0.10.1-0.50.20.6-0.60.60.0-0.60.2
Locomotion in novel chamber post-restriction0.91.11.8-0.60.9-0.71.0-1.30.71.2-1.21.2-0.7-1.21.2
Progressive ratio1.21.43.11.5-1.41.4-1.71.8-1.0-0.70.7-0.7-0.10.7-1.2
Food seeking constrained by brief footshock0.20.20.4-0.2-0.50.1-0.60.2-0.5-0.60.6-0.60.40.6-0.6
Seeking ratio, punishment vs. effort0.70.92.9-1.70.8-1.41.1-1.70.40.4-0.40.40.3-0.40.7
Run reversals in cocaine runway, females1.31.33.1-1.40.8-1.6-0.3-1.80.41.2-1.21.2-0.7-1.21.0
Run reversals in cocaine runway, males0.20.21.00.1-0.60.4-1.00.3-0.6-0.10.1-0.1-0.10.1-0.5
Latency to leave start box in cocaine runway4.44.87.2-1.72.5-1.62.2-2.52.12.4-2.42.4-1.2-2.42.7
Latency to leave start box in cocaine runway, F6.87.510.9-1.93.0-2.02.8-3.12.43.0-3.03.0-1.5-3.03.3
Latency to leave start box in cocaine runway, M0.10.10.3-0.3-0.3-0.2-0.50.1-0.2-0.40.4-0.40.30.4-0.3
Cd content in liver0.80.91.7-0.2-1.20.1-1.30.2-1.2-0.90.9-0.91.10.9-1.3
Co content in liver0.20.21.4-0.60.0-0.50.5-0.5-0.2-0.30.3-0.31.20.3-0.2
Cu content in liver0.70.84.00.01.60.32.00.11.50.2-0.20.2-0.0-0.21.0
Fe content in liver1.41.72.5-1.2-1.1-0.7-1.5-0.7-1.6-1.41.4-1.41.31.4-1.4
K content in liver0.20.20.70.60.40.30.80.10.40.4-0.40.4-0.4-0.40.3
Mg content in liver0.50.51.0-0.31.0-0.61.0-0.60.90.5-0.50.5-0.6-0.50.8
Mn content in liver0.40.41.51.1-0.41.20.10.8-0.3-0.40.4-0.40.80.4-0.7
Na content in liver2.02.17.1-1.02.3-1.02.7-1.41.70.9-0.90.9-0.0-0.91.8
Rb content in liver1.01.34.3-0.5-1.0-0.7-0.8-0.3-1.6-1.01.0-1.02.11.0-1.4
Se content in liver1.72.17.31.61.81.71.91.62.70.1-0.10.1-1.1-0.11.0
Sr content in liver0.40.31.00.20.80.21.00.70.8-0.40.4-0.40.80.40.2
Zn content in liver0.70.81.50.80.81.20.80.21.20.9-0.90.9-0.6-0.90.8