Ffar4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000021763 0.38 0.09 0.0e+00 0.21 0.2 0.21 0.21 3.8e-23 5.1e-22 5.2e-23 2.5e-23
2 Adipose mRNA stability ENSRNOG00000021763 0.19 0.08 1.1e-11 0.1 0.09 0.07 0.09 6.7e-11 1.9e-10 1.9e-08 1.1e-09
3 BLA gene expression ENSRNOG00000021763 0.29 0.08 1.2e-15 0.27 0.26 0.2 0.27 1.1e-14 1.9e-14 8.2e-11 8.4e-15
4 BLA mRNA stability ENSRNOG00000021763 0.13 0.07 2.3e-05 0.05 0.07 0.07 0.07 1.3e-03 8.4e-05 1.7e-04 1.6e-04
5 Brain gene expression ENSRNOG00000021763 0.12 0.04 5.6e-17 0.17 0.17 0.18 0.17 5.6e-16 1.3e-15 1.2e-16 4.9e-16
6 IL gene expression ENSRNOG00000021763 0.2 0.1 8.6e-05 0.13 0.18 0.18 0.15 4.8e-04 3.9e-05 4.9e-05 2.1e-04
7 Liver gene expression ENSRNOG00000021763 0.23 0.06 0.0e+00 0.29 0.28 0.29 0.29 9.7e-33 1.3e-31 2.0e-32 4.5e-32
8 NAcc gene expression ENSRNOG00000021763 0.31 0.07 0.0e+00 0.43 0.42 0.42 0.43 2.0e-34 1.9e-33 4.4e-34 1.9e-34
9 OFC gene expression ENSRNOG00000021763 0.18 0.1 1.1e-03 0.04 0.09 0.02 0.05 5.0e-02 3.8e-03 9.5e-02 2.6e-02
10 PL gene expression ENSRNOG00000021763 0.35 0.1 3.9e-14 0.16 0.17 0.16 0.15 6.0e-12 8.6e-13 8.0e-12 2.7e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail0.61.93.71.41.8-1.90.8-1.1-1.3-1.4-1.4-0.7-1.5
BMI without tail1.22.53.41.01.4-1.81.5-1.3-1.8-1.7-1.8-1.5-1.7
Body weight0.31.22.5-0.51.2-0.61.4-1.2-1.3-0.9-1.2-1.6-0.2
Epididymis fat weight0.41.02.00.31.0-1.01.1-0.9-1.2-1.0-1.4-1.0-0.1
Glucose0.20.21.3-1.10.20.10.2-0.2-0.3-0.2-0.1-0.90.2
Heart weight0.91.23.9-2.0-1.11.6-0.51.00.31.00.8-0.71.1
Left kidney weight0.41.15.6-2.4-0.71.4-0.20.50.40.90.6-0.41.1
Right kidney weight1.43.88.8-3.0-1.92.8-1.21.61.42.01.90.32.2
Tail length0.41.13.5-1.8-0.10.61.4-0.9-0.9-0.3-0.6-1.90.3
Length with tail0.31.24.9-2.2-0.91.60.7-0.3-0.00.60.4-1.11.4
Length without tail0.40.93.6-1.9-0.51.6-0.00.00.70.80.80.01.2
Liver weight, left0.60.94.2-2.00.40.91.0-0.5-0.40.1-0.3-1.21.1
Liver weight, right0.30.52.2-1.50.10.70.1-0.10.10.30.0-0.51.2
Parametrial fat weight0.40.82.6-1.6-1.21.1-0.60.70.30.50.4-0.41.4
Retroperitoneal fat weight0.10.31.5-0.6-0.30.4-0.10.3-0.30.2-0.1-0.71.2
Intraocular pressure0.30.41.01.0-0.70.5-0.50.50.30.70.70.40.4
Extensor digitorum longus weight0.10.51.1-0.11.0-0.40.7-1.0-0.7-0.7-0.9-0.8-0.2
Soleus weight1.23.66.70.52.2-1.52.1-2.1-2.3-1.8-1.9-2.6-0.7
Tibialis anterior weight0.51.83.40.61.9-1.11.3-1.7-1.1-1.5-1.6-1.0-1.0
Tibia length0.20.51.6-1.3-0.61.00.10.30.20.50.5-0.30.9
Number of licking bursts1.21.44.31.5-0.80.6-1.11.11.41.01.22.10.1
Food consumed during 24 hour testing period0.20.31.5-1.2-0.20.80.10.20.20.50.4-0.2-0.1
Times rat made contact with spout0.60.72.51.60.5-0.90.5-0.6-0.5-0.9-0.90.1-0.8
Mean time between licks in bursts0.40.51.7-1.3-1.00.8-0.60.70.40.40.4-0.10.6
Mean num. licks in bursts2.02.44.5-0.41.3-1.41.5-1.6-1.9-1.7-1.9-2.1-0.8
Std. dev. time between licks in bursts2.52.94.4-0.4-2.01.6-1.92.11.61.71.71.42.1
Water consumed over 24 hours1.21.43.41.30.9-1.31.0-1.2-0.8-1.4-1.2-0.3-1.8
Indifference point 0 sec0.61.02.7-0.8-1.61.5-0.41.00.70.91.00.21.1
Indifference point AUC4.04.76.7-0.7-2.22.6-2.02.02.42.52.51.92.1
Indifference point function ln k4.46.38.20.52.6-2.62.6-2.4-2.8-2.8-2.9-2.5-2.4
Indifference point function log k4.46.38.20.52.6-2.62.6-2.4-2.8-2.8-2.9-2.5-2.4
Delay discounting total patch changes 0 sec0.60.92.5-0.8-1.61.4-0.30.90.60.80.90.11.1
Delay discounting total patch changes 12 sec4.05.37.3-0.2-2.72.4-2.42.52.52.42.62.32.2
Delay discounting total patch changes 18 sec0.81.11.70.6-1.31.0-1.01.11.11.01.01.30.7
Delay discounting total patch changes 24 sec0.70.92.4-1.0-1.31.6-0.10.70.70.90.80.11.2
Delay discounting total patch changes 6 sec3.45.28.3-1.5-2.92.8-1.82.32.22.62.61.62.1
Delay discounting time to switch 0 sec0.81.23.50.8-0.70.6-1.31.11.41.11.21.90.5
Delay discounting water rate 0 sec1.21.93.4-0.31.0-1.11.6-1.4-1.6-1.6-1.6-1.8-1.2
Delay discounting water rate 12 sec0.81.12.5-1.00.8-0.41.4-1.0-1.2-0.8-1.1-1.6-0.9
Delay discounting water rate 18 sec1.72.34.2-0.71.4-0.92.0-1.6-1.6-1.5-1.6-1.9-1.3
Delay discounting water rate 24 sec0.81.12.2-0.31.0-0.61.5-1.1-1.2-1.1-1.1-1.3-0.6
Delay discounting water rate 6 sec0.10.20.4-0.10.5-0.30.4-0.3-0.5-0.4-0.4-0.7-0.3
Locomotor activity0.30.51.30.70.2-0.70.8-0.4-0.5-0.9-0.6-0.2-1.1
Locomotor testing distance0.40.72.00.70.3-0.81.0-0.6-0.6-1.1-0.8-0.3-1.4
Locomotor testing rearing1.11.73.20.90.8-1.21.5-1.4-1.2-1.6-1.3-0.8-1.8
Light reinforcement 10.20.32.01.4-0.5-0.0-0.40.40.20.40.40.60.4
Light reinforcement 21.21.64.02.0-0.7-0.2-1.61.31.21.01.01.90.5
Reaction time number correct2.33.36.01.02.5-1.91.9-1.9-1.8-2.0-2.0-1.2-1.5
Reaction time mean minus median0.60.82.8-1.70.40.20.9-0.5-0.9-0.3-0.4-1.6-0.4
Reaction time mean minus median AUC0.30.41.5-1.20.30.10.6-0.1-0.7-0.2-0.3-1.1-0.2
Reaction time num false alarms0.30.51.1-1.0-0.80.9-0.00.30.40.70.6-0.11.1
Reaction time num false alarms AUC0.40.61.7-1.3-0.81.00.10.30.30.70.6-0.21.0
Reaction time trials correct on left2.33.36.01.02.5-1.91.9-1.9-1.8-2.0-2.0-1.2-1.5
Reaction time trials on left2.33.25.90.92.4-1.91.9-1.8-1.8-2.0-2.0-1.2-1.4
Reaction time mean0.91.23.2-1.8-1.31.4-0.71.10.71.11.1-0.10.8
Reaction time mean AUC1.31.73.3-1.8-1.61.6-1.11.31.01.41.40.31.0
Median of all reaction times1.01.42.4-1.3-1.51.4-1.11.31.01.31.20.41.0
Reaction time omissions1.01.44.0-2.00.8-0.21.2-0.7-1.2-0.8-1.1-1.8-0.7
Reaction time false alarm rate1.42.03.4-1.5-1.81.8-0.91.11.21.61.50.41.7
Reaction time premature initiation rate0.81.13.1-1.8-0.91.3-0.30.70.71.10.9-0.11.4
Reaction time premature initiations0.30.41.8-1.30.40.20.7-0.4-0.40.0-0.3-0.90.6
Std. dev. reaction times0.71.06.0-2.4-0.61.00.30.3-0.30.50.3-1.30.4
Reaction time trials completed2.33.25.90.92.4-1.91.9-1.8-1.8-2.0-2.0-1.2-1.4
Reaction time trials AUC2.02.95.70.92.4-1.81.8-1.7-1.7-1.9-1.9-1.1-1.4
Social response proportion3.03.35.51.62.1-2.31.4-1.7-1.8-2.0-1.9-1.2-1.8
Social responses0.60.71.30.80.7-1.10.8-0.9-1.1-0.7-0.7-1.1-0.3
Social time0.70.91.1-0.5-0.91.0-0.90.91.01.01.00.91.0
Conditioned locomotion0.10.10.3-0.30.2-0.20.3-0.0-0.5-0.2-0.5-0.50.6
Cocaine response after cond. corrected0.10.20.3-0.60.10.6-0.20.30.40.50.50.20.3
Cocaine response after cond. not corrected0.10.10.5-0.70.10.5-0.10.00.40.30.40.20.1
Cocaine response before conditioning0.00.10.10.2-0.3-0.1-0.2-0.10.3-0.20.20.4-0.4
Saline control response2.73.65.20.1-2.31.7-2.01.82.21.61.92.32.2
Condit. Reinf. active minus inactive responses2.22.83.71.01.8-1.81.7-1.8-1.7-1.7-1.9-1.3-1.7
Condit. Reinf. active-inactive response ratio1.51.62.51.31.5-1.60.9-1.2-1.1-1.2-1.3-0.4-1.5
Condit. Reinf. active responses0.40.51.4-0.10.3-0.50.8-0.7-1.0-0.6-0.8-1.20.1
Condit. Reinf. inactive responses1.31.64.0-1.6-1.71.5-0.61.00.51.11.0-0.32.0
Condit. Reinf. lever presses0.30.41.3-0.2-1.10.5-0.40.60.50.60.60.40.7
Condit. Reinf. lever reinforcers received0.10.20.5-0.0-0.0-0.30.5-0.5-0.6-0.3-0.5-0.70.3
Pavlov. Cond. lever latency1.41.93.90.91.6-1.70.8-1.3-1.1-1.7-1.5-0.6-2.0
Pavlov. Cond. magazine entry latency0.20.31.8-1.30.00.70.5-0.00.00.1-0.0-0.4-0.1
Pavlov. Cond. change in total contacts0.50.71.5-0.8-0.81.2-0.40.60.71.00.70.41.1
Pavlov. Cond. index score0.60.81.9-1.3-0.91.4-0.20.60.71.10.80.21.1
Pavlov. Cond. latency score0.50.61.7-1.3-0.71.2-0.00.50.50.80.60.00.9
Pavlov. Cond. lever contacts1.31.83.9-0.9-1.71.6-0.71.21.01.51.30.52.0
Pavlov. Cond. magazine entry number1.72.14.42.01.3-2.10.8-1.3-1.4-1.5-1.3-0.7-1.4
Pavlov. Cond. intertrial magazine entries1.01.32.21.31.1-1.50.8-1.1-1.0-1.3-1.1-0.5-1.3
Pavlov. Cond. lever-magazine prob. diff.0.50.61.6-1.2-0.71.3-0.10.50.60.90.70.20.8
Pavlov. Cond. response bias1.11.63.2-1.3-1.51.8-0.51.11.11.41.20.51.6
Conditioned reinforcement - actives0.70.71.3-0.40.5-0.51.1-1.1-0.7-0.9-0.6-0.8-1.2
Conditioned reinforcement - inactives3.33.77.90.41.9-1.72.1-2.4-1.8-2.0-1.6-1.7-2.8
Conditioned locomotion0.10.10.8-0.3-0.20.20.3-0.3-0.4-0.10.1-0.90.1
Intermittent access intake day 1-15 change3.93.96.1-0.21.4-1.72.4-2.1-2.3-2.2-1.9-2.5-2.0
Intermittent access intake escalation3.33.25.3-0.51.3-1.42.3-1.9-2.1-1.9-1.7-2.3-1.8
Intermittent access intake escalation 24.84.87.70.11.7-2.22.5-2.3-2.4-2.4-2.2-2.2-2.8
Intermitt. access day 1 inactive lever presses0.20.30.40.70.4-0.50.4-0.4-0.6-0.5-0.6-0.5-0.4
Intermitt. access day 15 inactive lever presses0.70.71.61.10.5-0.70.8-0.8-1.1-0.8-0.8-1.3-0.2
Intermitt. access escalation Index1.21.12.50.01.1-1.60.7-0.7-1.1-1.4-1.5-0.8-0.7
Intermittent access day 1 total infusions0.60.61.00.00.9-0.60.8-1.0-0.8-0.9-0.8-1.0-0.7
Intermittent access day 15 total infusions3.13.57.1-1.11.6-1.32.1-2.0-2.2-1.9-1.7-2.7-1.6
Intermittent access terminal intake (last 3 days)2.83.04.7-0.31.5-1.51.8-1.9-2.0-2.0-1.7-2.2-1.9
Intermittent access total infusions1.61.82.8-0.21.3-1.21.3-1.5-1.5-1.5-1.3-1.7-1.4
Intermittent access day 1 locomotion0.20.20.9-0.90.60.20.2-0.4-0.3-0.1-0.1-0.80.1
Intermittent access day 15 total locomotion0.20.20.6-0.6-0.60.8-0.10.10.20.40.7-0.30.5
Intermittent access total locomotion0.00.00.10.0-0.00.4-0.1-0.10.20.10.40.00.0
Intermittent access standard deviation3.94.27.3-1.01.6-1.62.4-2.2-2.3-2.1-2.0-2.7-2.1
Cocaine induced anxiety0.50.61.10.81.0-1.00.2-0.6-0.2-1.0-0.70.3-0.9
Post-drug Anxiety1.01.12.41.4-0.50.3-1.31.01.00.60.71.51.2
Baseline Anxiety1.21.33.50.1-1.21.2-1.01.10.81.51.10.51.9
Lifetime Intake0.80.91.5-0.00.9-0.80.8-1.0-1.1-1.1-0.8-1.2-1.0
Incentive Sensitization - Responses4.74.66.40.32.0-1.92.5-2.4-2.4-2.5-2.0-2.4-2.2
Incentive Sensitization - Breakpoint4.14.15.90.21.8-1.72.4-2.3-2.3-2.3-1.9-2.3-2.0
Progressive ratio test 1 active lever presses0.70.70.90.70.8-0.90.6-0.9-0.9-1.0-0.8-0.8-0.7
Progressive ratio test 1 breakpoint0.70.81.10.80.8-1.00.6-1.0-1.0-1.0-0.9-0.8-0.7
Progressive ratio test 1 inactive lever presses3.53.84.61.41.9-1.92.0-2.1-2.1-2.1-2.1-2.0-1.6
Progressive ratio test 2 active lever presses2.62.73.90.21.5-1.32.0-1.9-1.9-1.9-1.5-2.0-1.5
Progressive ratio test 2 breakpoint3.13.55.00.41.6-1.52.1-2.2-2.2-2.2-1.7-2.2-1.7
Progressive ratio test 2 inactive lever presses2.32.73.71.11.6-1.71.6-1.8-1.7-1.9-1.5-1.3-1.9
Total sessions with >9 infusions0.10.10.40.5-0.60.4-0.20.20.10.20.6-0.00.2
Short access day 1 total inactive lever presses3.03.37.62.71.7-2.60.9-1.4-1.7-1.8-1.7-0.8-1.8
Short access day 10 total inactive lever presses0.20.21.21.10.2-0.4-0.30.10.0-0.4-0.40.5-0.0
Short access day 1 total infusions0.20.30.60.4-0.50.2-0.80.50.40.40.60.60.4
Short access day 10 total infusions0.20.20.4-0.7-0.60.6-0.40.50.20.40.5-0.30.6
Short access total infusions0.10.10.20.30.0-0.20.1-0.2-0.3-0.3-0.0-0.4-0.2
Short access day 1 locomotion0.10.10.80.90.0-0.3-0.2-0.00.0-0.20.10.3-0.1
Short access day 10 total locomotion0.10.10.5-0.10.70.0-0.10.00.10.30.20.2-0.1
Short access total locomotion0.20.20.40.6-0.30.1-0.60.40.40.30.40.60.2
Compulsive drug intake2.92.94.9-0.61.4-1.81.6-1.7-1.8-2.0-2.2-2.0-1.3
One hour access (0.3 mA shock)6.37.49.60.02.7-2.43.1-3.1-3.0-3.1-2.6-3.1-2.6
One hour access (shock baseline)0.91.11.9-0.01.1-0.61.4-1.2-1.2-1.1-0.7-1.3-1.0
Number of responses in last shaping day0.20.20.80.40.4-0.9-0.1-0.2-0.6-0.5-0.5-0.30.0
Context. condit. distance diff. score1.31.52.50.11.4-1.21.2-1.6-1.2-1.3-1.3-1.1-1.3
Locomotion velocity, session 11.31.42.60.8-1.31.0-1.21.31.31.31.41.60.2
Locomotion distance, session 10.50.71.10.5-0.90.7-0.70.90.91.00.91.00.6
Locomotion velocity, session 20.80.94.40.50.8-0.80.9-0.9-0.5-0.8-0.7-0.2-2.1
Locomotion distance, session 20.10.10.30.30.30.30.4-0.20.2-0.00.10.4-0.6
Locomotion velocity, session 30.30.40.6-0.40.3-0.40.8-0.7-0.6-0.7-0.6-0.7-0.7
Locomotion distance, session 30.60.71.9-1.40.3-0.20.9-0.8-0.7-0.5-0.7-1.2-0.7
Stereotopy head waving bouts, day 30.30.41.51.20.2-0.90.2-0.2-0.5-0.6-0.3-0.1-0.8
Stereotopy head waving duration, day 30.40.53.01.70.6-1.00.0-0.3-0.5-0.6-0.40.1-0.5
Locomotion velocity, session 72.93.14.30.42.0-1.61.9-2.1-1.9-1.9-2.1-1.8-1.4
Locomotion distance, session 71.92.43.6-0.31.7-1.11.8-1.9-1.7-1.6-1.7-1.9-1.1
Stereotopy head waving bouts, day 70.30.31.00.9-0.1-0.7-0.2-0.10.1-0.30.10.5-1.0
Stereotopy head waving duration, day 70.10.20.60.60.0-0.8-0.1-0.1-0.3-0.4-0.20.0-0.8
Locomotion velocity, session 80.30.40.60.20.6-0.80.5-0.7-0.6-0.7-0.6-0.5-0.7
Locomotion distance, session 80.71.12.60.61.3-1.01.0-1.3-0.6-1.1-0.9-0.2-1.6
Degree of sensitization distance0.30.31.11.00.9-0.30.3-0.6-0.2-0.5-0.30.1-0.0
Degree of sensitization stereotypy0.20.20.4-0.1-0.5-0.0-0.50.30.50.20.50.6-0.5
Condit. Reinf. active minus inactive responses0.10.10.6-0.8-0.30.60.20.00.20.20.10.1-0.4
Condit. Reinf. active-inactive response ratio0.10.10.5-0.7-0.40.4-0.10.20.20.40.20.0-0.2
Condit. Reinf. active responses0.20.21.0-1.0-0.20.80.20.00.20.20.0-0.10.2
Condit. Reinf. inactive responses0.10.10.4-0.10.10.5-0.00.10.20.20.10.20.6
Incentive salience index mean0.80.92.0-1.3-1.11.4-0.40.71.01.00.80.70.5
Condit. Reinf. lever presses2.43.24.3-1.1-1.92.1-1.61.82.02.01.81.71.8
Time in familiar zone, hab. session 10.50.52.31.50.6-0.90.2-0.4-0.6-0.3-0.4-0.2-0.5
Time in novel zone, hab. session 10.30.30.5-0.7-0.70.7-0.40.30.70.50.50.50.3
Total zone transitions, hab. session 10.00.00.10.3-0.10.10.2-0.10.00.20.10.20.0
Total locomotion distance, hab. session 10.81.22.30.5-1.21.0-0.81.11.21.21.21.50.8
Locomotion velocity, hab. session 11.72.44.00.1-1.71.5-1.41.61.81.71.72.01.3
Time in familiar zone, hab. session 20.10.10.30.3-0.50.1-0.30.4-0.00.30.2-0.10.6
Time in novel zone, hab. session 20.00.00.1-0.30.10.1-0.00.00.20.10.10.1-0.1
Total zone transitions, hab. session 20.81.01.6-0.3-1.21.2-0.71.01.01.31.10.81.0
Total locomotion distance, hab. session 20.91.21.9-0.1-1.31.3-0.81.21.11.41.30.91.1
Locomotion velocity, hab. session 21.11.42.00.1-1.31.3-0.91.31.31.41.41.31.1
Novel to familiar place preference ratio4.14.48.61.92.3-2.31.9-2.3-1.6-2.2-1.9-0.8-2.9
Novelty place preference4.44.68.72.02.3-2.42.0-2.3-1.7-2.3-1.9-0.9-3.0
Time in novel zone, NPP test4.54.89.31.92.4-2.42.0-2.4-1.7-2.3-2.0-1.0-3.0
Total zone transitions, NPP test1.01.52.6-1.0-1.21.6-0.81.11.21.51.20.91.4
Total locomotion distance, NPP test1.82.53.5-0.4-1.71.7-1.31.61.81.91.71.81.4
Locomotion velocity, NPP test1.82.63.5-0.7-1.71.8-1.31.61.91.91.71.71.5
Pavlov. Cond. lever latency0.10.10.20.5-0.2-0.2-0.30.3-0.20.10.2-0.20.4
Pavlov. Cond. magazine entry latency0.81.13.5-1.9-0.91.6-0.30.70.91.11.00.30.5
Pavlov. Cond. change in total contacts0.30.42.8-1.70.00.50.3-0.00.10.30.0-0.3-0.5
Pavlov. Cond. index score0.50.61.9-1.4-0.61.1-0.10.40.90.80.70.50.1
Pavlov. Cond. latency score0.40.51.6-1.3-0.51.1-0.10.30.80.70.60.50.1
Pavlov. Cond. lever contacts0.60.71.5-1.2-0.71.2-0.40.61.00.90.80.70.7
Pavlov. Cond. magazine entry number0.30.32.21.50.1-0.8-0.3-0.1-0.1-0.5-0.20.40.0
Pavlov. Cond. intertrial magazine entries0.00.00.2-0.2-0.20.2-0.00.20.10.1-0.00.10.4
Pavlov. Cond. lever-magazine prob. diff.0.50.62.0-1.4-0.61.1-0.20.40.90.80.70.60.1
Pavlov. Cond. response bias0.50.63.1-1.8-0.41.20.10.30.50.80.5-0.00.2
Bone: apparent density4.37.19.31.92.6-2.73.0-2.9-3.0-2.8-2.7-2.6-2.2
Bone surface3.46.08.71.22.4-2.22.9-2.7-2.9-2.4-2.4-2.8-2.0
Bone volume3.55.98.91.22.3-2.13.0-2.7-3.0-2.5-2.5-2.8-1.7
Bone: connectivity density5.89.211.42.22.9-3.23.1-3.1-3.4-3.2-3.1-2.8-3.1
Bone: cortical apparent density1.01.33.10.9-1.10.1-1.81.21.30.91.11.70.3
Bone: cortical area0.91.34.5-1.10.6-0.01.7-1.2-1.4-0.7-0.9-2.10.1
Bone: cortical porosity0.90.91.81.31.3-1.10.6-0.9-0.6-1.1-0.7-0.1-1.2
Bone: cortical porosity1.31.42.50.71.6-1.11.1-1.3-1.0-1.3-1.0-0.8-1.4
Bone: cortical thickness1.32.13.4-1.2-1.71.8-1.01.31.31.51.50.81.8
Bone: cortical thickness1.92.23.30.1-1.81.3-1.41.51.71.61.71.71.1
Bone: cortical tissue density1.01.33.01.0-1.0-0.0-1.71.11.30.81.01.70.2
Bone: elastic displacement0.60.74.12.00.3-1.1-0.50.3-0.2-0.5-0.50.6-0.5
Bone: elastic work1.21.54.92.20.9-1.80.4-0.6-0.9-1.3-1.1-0.1-1.3
Bone: endosteal estimation5.511.921.10.33.6-2.64.3-3.9-4.1-3.3-3.5-4.6-2.1
Bone: endosteal perimeter5.210.817.10.73.2-2.74.1-3.7-3.9-3.2-3.3-4.1-2.3
Bone: final force0.20.41.2-1.10.20.60.9-0.5-0.40.10.0-1.10.4
Bone: final moment0.30.51.6-1.00.20.60.9-0.4-0.60.1-0.1-1.30.6
Bone: marrow area5.712.121.20.43.6-2.64.3-4.0-4.2-3.3-3.5-4.6-2.1
Bone: maximum diameter6.011.016.60.93.3-2.94.0-3.8-3.9-3.4-3.4-4.1-2.3
Bone: maximum force0.81.43.6-0.21.0-0.51.7-1.5-1.5-0.9-0.9-1.9-0.5
Bone: maximum moment0.81.44.3-0.11.0-0.41.7-1.3-1.6-0.8-1.0-2.1-0.3
Bone: minimum diameter7.013.025.7-0.83.4-2.64.4-4.1-4.3-3.4-3.7-5.1-2.3
Bone: periosteal estimation3.57.215.2-0.12.5-1.73.6-3.1-3.3-2.4-2.6-3.9-1.2
Bone: periosteal perimeter3.76.110.30.32.4-1.93.1-2.8-3.0-2.4-2.5-3.2-1.5
Bone: post-yield work1.21.63.9-0.30.9-0.41.8-1.5-1.6-0.9-1.0-2.0-1.0
Bone: stiffness0.81.33.1-0.70.9-0.31.5-1.5-1.3-1.0-1.0-1.8-0.5
Bone: tissue strength0.20.20.7-0.50.30.10.2-0.1-0.4-0.1-0.2-0.80.4
Bone: trabecular number3.85.88.01.42.3-2.42.7-2.6-2.8-2.5-2.4-2.5-2.3
Bone: trabecular spacing2.12.73.6-1.6-1.91.8-1.71.81.71.71.51.31.6
Bone: trabecular thickness2.83.45.30.71.6-1.72.2-1.9-2.3-1.9-2.0-2.2-1.4
Bone: trabecular tissue density0.50.71.00.60.6-1.00.7-1.0-0.9-1.0-0.9-0.7-0.5
Breakpoint value in progressive ratio session0.30.31.1-0.1-0.50.9-0.20.10.50.60.60.31.0
Distance traveled before self-admin1.01.12.90.40.6-0.91.1-1.2-0.8-1.2-1.2-0.6-1.7
Distance traveled after self-admin3.94.36.32.52.0-2.31.8-2.2-1.9-2.2-1.9-1.2-2.5
Delta time in closed arm before/after self-admin0.60.61.8-1.3-0.41.30.00.40.30.90.6-0.40.9
Delta time in open arm before/after self-admin1.41.33.11.21.1-1.60.7-1.1-0.7-1.3-1.10.0-1.7
Diff in mean of infusions in LGA sessions1.82.02.7-0.11.5-1.21.5-1.6-1.5-1.4-1.6-1.6-1.4
Extinction: sum of active levers before priming0.20.20.6-0.6-0.00.70.5-0.3-0.20.30.1-0.80.3
Active lever presses in extinction session 63.83.65.91.92.4-1.92.1-2.3-1.6-1.9-1.8-0.9-1.9
Delta distance traveled before/after self-admin1.71.83.41.81.6-1.61.0-1.3-1.4-1.3-1.2-1.0-0.8
Delta ambulatory time before/after self-admin2.62.84.01.72.0-1.91.4-1.8-1.8-1.8-1.7-1.4-1.2
Time in closed arm before self-admin2.12.44.71.81.5-1.81.3-1.4-1.2-1.7-1.5-0.4-2.2
Time in closed arm after self-admin0.10.10.30.3-0.10.60.10.10.30.30.10.40.1
Time in open arm before self-admin0.20.21.00.1-0.30.4-0.40.50.20.30.30.11.0
Time in open arm after self-admin0.20.20.40.60.2-0.60.4-0.4-0.3-0.5-0.30.1-0.5
Sum of active levers in priming session hrs 5-60.10.10.10.40.4-0.20.4-0.1-0.40.0-0.3-0.3-0.1
Time to tail flick, vehicle, before self-admin0.90.94.22.0-0.2-0.4-1.10.70.60.30.51.30.3
Time to tail flick, vehicle, after self-admin0.50.61.4-0.20.80.01.2-1.1-0.6-0.7-0.8-0.7-0.3
Time to tail flick, test, before self-admin2.52.54.10.91.6-1.51.7-2.0-1.5-1.6-1.4-1.5-1.8
Time to tail flick, test, after self-admin1.61.63.31.81.2-1.61.0-1.2-1.1-1.4-1.5-0.5-0.9
Delta time to tail flick, vehicle, before/after SA2.01.94.3-1.31.3-0.22.1-1.8-1.2-1.1-1.3-1.6-1.0
Delta time to tail flick, test, before/after SA0.10.10.30.6-0.0-0.40.10.1-0.2-0.2-0.40.20.1
Ambulatory time before self-admin0.70.72.50.50.4-0.90.7-0.8-0.5-1.0-0.9-0.2-1.6
Ambulatory time after self-admin6.97.612.23.02.7-3.12.3-2.9-2.4-2.9-2.6-1.5-3.5
Total heroin consumption0.10.20.6-0.3-0.20.8-0.00.00.20.50.5-0.10.7
Area under the delay curve0.40.41.20.7-0.70.4-0.50.50.70.20.61.10.5
Delay disc. indifference point, 0s delay1.31.42.81.40.8-1.50.9-1.1-0.9-1.7-1.3-0.1-1.4
Delay disc. indifference point, 16s delay0.40.40.80.1-0.80.8-0.50.40.60.30.90.60.7
Delay disc. indifference point, 2s delay0.30.43.01.7-0.1-0.6-0.10.1-0.1-0.0-0.10.6-0.1
Delay disc. indifference point, 24s delay1.21.11.8-0.6-1.01.3-0.90.91.31.21.31.10.9
Delay disc. indifference point, 4s delay0.40.41.70.9-0.60.2-0.60.40.80.00.51.30.2
Delay disc. indifference point, 8s delay2.02.13.80.5-1.51.2-1.41.51.61.41.52.01.6
Delay discount exponential model param0.40.41.3-0.60.7-0.50.5-0.5-0.8-0.4-0.7-1.1-0.5
Delay discount hyperbolic model param0.30.41.1-0.80.6-0.30.4-0.5-0.6-0.2-0.5-1.0-0.4
Fecal boli incidents, locomotor time 11.01.12.10.91.3-1.30.7-1.1-0.8-1.4-0.9-0.4-1.3
Change in fecal boli incidents, locomotor task1.21.11.8-0.6-1.31.3-0.91.01.11.31.10.80.9
Time >=10cm from walls, locomotor time 11.41.410.4-3.20.20.90.8-0.7-0.10.2-0.1-1.3-0.1
Bouts of movement, locomotor time 10.10.10.70.9-0.1-0.00.2-0.0-0.0-0.6-0.00.30.1
Total resting periods, locomotor time 10.10.10.60.8-0.20.20.10.00.2-0.50.20.50.1
Rest time, locomotor task time 11.11.25.12.30.7-1.10.5-0.7-0.5-1.6-0.80.2-0.9
Distance moved, locomotor task time 11.41.56.7-2.6-1.01.5-0.50.50.71.50.9-0.20.9
Vertical activity count, locomotor time 11.21.36.0-2.4-0.71.3-0.30.60.51.60.9-0.20.8
Time >=10cm from walls, locomotor time 20.50.51.6-1.30.2-0.00.7-0.9-0.2-0.7-0.7-0.5-0.8
Bouts of movement, locomotor time 21.71.95.30.9-1.40.9-1.41.31.70.91.52.30.1
Total resting periods, locomotor time 21.61.75.10.9-1.40.9-1.21.21.70.71.42.30.0
Rest time, locomotor task time 20.30.41.50.8-0.50.4-0.30.40.90.20.61.20.2
Distance moved, locomotor task time 20.70.82.7-1.60.6-0.00.7-0.8-0.8-0.2-0.9-1.4-0.3
Vertical activity count, locomotor time 20.40.41.4-1.20.6-0.20.6-0.6-0.6-0.2-0.5-1.0-0.4
Weight adjusted by age0.50.54.12.00.3-0.6-0.2-0.1-0.0-0.4-0.10.70.3
Seeking ratio, delayed vs. immediate footshock0.20.20.5-0.6-0.70.6-0.40.30.40.20.50.10.4
Locomotion in novel chamber3.44.26.11.62.3-2.22.0-2.0-2.0-2.3-2.0-1.4-2.5
Locomotion in novel chamber post-restriction0.10.10.30.2-0.30.5-0.0-0.10.50.40.60.30.1
Progressive ratio0.20.20.9-0.5-0.10.5-0.10.50.10.20.1-0.11.0
Food seeking constrained by brief footshock0.60.83.0-1.7-0.61.11.1-0.4-0.30.10.2-1.2-0.3
Seeking ratio, punishment vs. effort0.20.30.6-0.6-0.40.50.8-0.6-0.10.10.1-0.6-0.7
Run reversals in cocaine runway, females0.20.21.21.1-0.00.2-0.10.20.20.30.30.5-0.2
Run reversals in cocaine runway, males3.33.24.8-0.9-2.01.8-1.81.91.92.22.01.51.5
Latency to leave start box in cocaine runway2.22.43.50.81.3-1.81.4-1.5-1.9-1.8-1.8-1.7-1.4
Latency to leave start box in cocaine runway, F3.53.85.11.11.6-2.31.8-1.9-2.2-2.3-2.2-1.9-2.0
Latency to leave start box in cocaine runway, M0.10.10.4-0.10.2-0.20.5-0.3-0.5-0.2-0.4-0.70.1
Cd content in liver1.61.83.1-1.1-1.71.8-1.21.41.01.41.50.51.4
Co content in liver0.40.41.00.3-1.00.1-0.70.90.30.60.50.30.9
Cu content in liver3.94.87.00.7-2.31.7-2.32.32.42.22.42.62.1
Fe content in liver1.82.24.4-0.2-1.31.2-1.81.81.81.41.52.10.6
K content in liver0.20.21.40.40.10.0-0.40.20.7-0.10.31.2-0.1
Mg content in liver0.70.72.3-0.0-0.40.7-0.80.81.20.60.91.50.4
Mn content in liver2.32.67.60.5-0.80.9-1.91.52.21.61.82.80.6
Na content in liver1.81.96.00.5-0.80.8-1.71.31.91.11.32.50.4
Rb content in liver0.20.20.5-0.50.5-0.10.7-0.6-0.4-0.4-0.5-0.5-0.1
Se content in liver16.720.233.9-0.0-4.13.8-5.24.85.54.75.05.83.2
Sr content in liver0.10.10.3-0.6-0.20.3-0.0-0.0-0.2-0.00.2-0.6-0.1
Zn content in liver1.61.83.90.1-1.10.9-1.71.61.71.21.32.00.6