Hub : Genes

Atp8b5p

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000021704 0.31 0.16 0.0e+00 0.25 0.25 0.26 0.26 2.2e-27 1.4e-27 2.3e-28 2.0e-28
2 Adipose mRNA stability ENSRNOG00000021704 0.07 0.05 3.0e-08 0.06 0.05 0.04 0.05 2.6e-07 2.2e-06 8.7e-06 2.7e-06
3 BLA gene expression ENSRNOG00000021704 0.16 0.11 3.7e-07 0.1 0.11 0.12 0.1 6.0e-06 1.8e-06 8.1e-07 4.3e-06
4 Brain gene expression ENSRNOG00000021704 0.14 0.08 1.7e-11 0.14 0.13 0.14 0.14 1.4e-12 7.6e-12 1.3e-12 9.4e-13
5 Brain mRNA stability ENSRNOG00000021704 0.08 0.05 3.3e-07 0.07 0.06 0.07 0.07 1.9e-07 1.5e-06 5.1e-07 2.6e-07
6 IL gene expression ENSRNOG00000021704 0.14 0.09 1.2e-03 0.1 0.03 0.08 0.05 2.6e-03 8.1e-02 4.8e-03 2.8e-02
7 LHb gene expression ENSRNOG00000021704 0.14 0.11 8.5e-03 0.06 0 0.05 0.04 1.6e-02 2.9e-01 3.1e-02 4.6e-02
8 Liver gene expression ENSRNOG00000021704 0.42 0.15 0.0e+00 0.34 0.38 0.38 0.38 2.0e-38 9.7e-45 7.5e-45 3.3e-44
9 Liver intron excision ratio chr5:57549297:57564476 0.09 0.06 4.1e-08 0.04 0.06 0.05 0.05 2.1e-05 9.0e-07 2.5e-06 5.7e-06
10 Liver intron excision ratio chr5:57583252:57586245 0.03 0.02 2.8e-03 0.02 0.02 0.01 0.01 3.2e-03 2.3e-03 9.8e-03 7.9e-03
11 Liver intron excision ratio chr5:57583252:57597426 0.04 0.03 4.0e-03 0.02 0.01 0.01 0.01 6.0e-03 9.2e-03 1.1e-02 2.0e-02
12 Liver mRNA stability ENSRNOG00000021704 0.16 0.1 5.6e-17 0.14 0.14 0.14 0.15 7.2e-15 9.0e-16 1.3e-15 1.5e-16
13 NAcc gene expression ENSRNOG00000021704 0.14 0.09 1.7e-11 0.14 0.16 0.16 0.16 2.1e-10 7.1e-12 1.3e-11 6.7e-12
14 PL gene expression ENSRNOG00000021704 0.09 0.06 1.2e-07 0.07 0.07 0.07 0.08 4.5e-06 2.9e-06 6.7e-06 1.7e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail2.27.210.53.12.52.82.63.03.23.02.9-1.9-1.8-0.93.12.72.9
BMI without tail5.511.615.13.63.63.43.93.73.73.63.8-0.9-3.40.73.93.53.7
Body weight3.213.417.43.94.13.84.13.84.03.84.0-1.2-3.50.54.24.04.0
Epididymis fat weight0.51.31.91.11.41.41.30.91.20.91.10.0-1.30.51.31.31.2
Glucose1.01.62.21.31.21.41.51.31.41.31.4-0.2-1.30.41.41.31.4
Heart weight0.71.01.60.81.31.11.20.80.90.81.00.2-1.20.71.01.10.9
Left kidney weight0.41.22.90.81.20.91.40.70.90.71.10.8-1.71.31.20.90.9
Right kidney weight0.10.21.0-0.10.20.00.4-0.20.0-0.20.10.8-0.71.00.20.00.1
Tail length2.67.811.42.93.12.73.42.82.82.83.1-0.2-3.11.23.12.93.0
Length with tail0.83.05.41.52.21.72.21.41.51.41.80.6-2.31.51.91.91.8
Length without tail0.40.91.5-1.1-0.8-1.0-0.9-1.2-1.2-1.2-1.10.80.60.3-1.0-0.9-1.0
Liver weight, left0.40.71.20.80.80.81.00.91.10.90.9-0.3-0.80.11.00.90.8
Liver weight, right0.10.10.2-0.5-0.0-0.3-0.0-0.3-0.4-0.3-0.30.5-0.10.4-0.3-0.2-0.3
Parametrial fat weight0.20.40.80.50.70.30.80.40.70.30.60.4-0.90.60.70.50.6
Retroperitoneal fat weight0.10.30.5-0.5-0.4-0.3-0.7-0.5-0.1-0.5-0.6-0.40.7-0.7-0.5-0.4-0.5
Intraocular pressure2.02.84.61.82.01.32.11.51.41.51.90.3-2.11.11.91.81.8
Extensor digitorum longus weight4.317.523.54.24.84.74.74.44.24.44.6-1.2-4.10.64.54.64.7
Soleus weight0.51.57.6-0.80.6-0.60.5-0.9-1.0-0.8-0.22.6-1.52.8-0.3-0.1-0.4
Tibialis anterior weight6.522.632.54.75.74.95.64.74.64.75.1-0.5-5.11.65.35.45.2
Tibia length0.20.63.3-0.50.7-0.20.5-0.2-0.4-0.2-0.01.7-1.11.8-0.00.3-0.2
Number of licking bursts4.95.87.92.62.82.82.42.62.72.62.5-1.4-1.8-0.52.62.82.6
Food consumed during 24 hour testing period0.91.01.70.81.31.21.20.91.00.91.10.2-1.20.71.01.21.0
Times rat made contact with spout0.40.40.80.40.60.80.50.70.90.70.5-0.9-0.1-0.80.40.70.6
Mean time between licks in bursts0.30.40.6-0.8-0.6-0.6-0.7-0.6-0.7-0.6-0.70.10.7-0.3-0.8-0.6-0.7
Mean num. licks in bursts2.53.04.7-2.0-2.2-1.9-1.8-1.7-1.7-1.7-1.90.51.6-0.2-2.0-2.0-1.9
Std. dev. time between licks in bursts0.30.40.6-0.6-0.8-0.5-0.7-0.6-0.8-0.6-0.70.00.7-0.2-0.7-0.7-0.7
Water consumed over 24 hours0.80.91.50.81.21.11.01.01.11.01.0-0.5-0.7-0.20.91.20.9
Indifference point 0 sec0.91.57.60.11.0-0.31.0-0.6-0.4-0.50.52.4-2.02.80.60.50.4
Indifference point AUC7.68.912.23.43.03.23.53.22.73.13.4-0.8-3.00.73.53.13.3
Indifference point function ln k2.53.54.7-2.1-1.7-2.1-2.1-2.1-1.9-2.1-2.20.81.7-0.1-2.1-1.9-2.1
Indifference point function log k2.53.54.7-2.1-1.7-2.1-2.1-2.1-1.9-2.1-2.20.81.7-0.1-2.1-1.9-2.1
Delay discounting total patch changes 0 sec1.01.76.70.61.40.21.4-0.1-0.0-0.00.92.1-2.22.61.00.90.8
Delay discounting total patch changes 12 sec1.92.53.51.71.61.51.91.61.51.61.8-0.5-1.60.31.81.71.8
Delay discounting total patch changes 18 sec0.70.91.61.01.00.81.20.90.60.81.20.3-1.30.81.11.01.0
Delay discounting total patch changes 24 sec2.22.74.61.71.81.72.11.51.11.51.90.3-2.11.21.81.71.8
Delay discounting total patch changes 6 sec2.43.67.51.82.31.52.41.31.11.42.11.0-2.72.02.11.92.0
Delay discounting time to switch 0 sec2.63.96.4-2.3-2.1-1.7-2.5-1.8-1.6-1.9-2.3-0.32.5-1.3-2.4-1.9-2.1
Delay discounting water rate 0 sec1.52.44.81.61.81.32.01.21.31.11.70.8-2.21.51.81.51.6
Delay discounting water rate 12 sec0.10.10.5-0.00.4-0.20.3-0.0-0.0-0.20.10.7-0.50.70.10.10.0
Delay discounting water rate 18 sec0.30.40.80.60.60.90.60.80.80.70.5-0.6-0.2-0.50.60.60.6
Delay discounting water rate 24 sec0.20.31.80.2-0.3-0.1-0.20.40.50.4-0.1-1.20.8-1.3-0.0-0.10.1
Delay discounting water rate 6 sec0.71.02.30.91.51.31.10.91.11.00.8-0.1-1.00.31.01.31.0
Locomotor activity0.00.00.30.10.20.60.20.00.20.00.10.0-0.10.00.20.30.1
Locomotor testing distance0.20.31.4-0.30.30.20.2-0.6-0.5-0.5-0.21.2-0.61.20.00.1-0.2
Locomotor testing rearing0.91.43.10.81.81.61.30.70.80.91.00.3-1.40.81.11.61.2
Light reinforcement 11.52.89.60.42.20.81.90.30.60.21.12.5-2.83.11.21.51.1
Light reinforcement 21.72.211.6-0.01.2-0.21.2-0.5-0.6-0.50.53.0-2.43.40.50.60.3
Reaction time number correct0.10.20.60.00.50.20.60.2-0.00.10.30.7-0.70.80.20.40.2
Reaction time mean minus median1.41.87.21.1-0.11.00.21.41.51.50.8-2.70.8-2.50.70.51.0
Reaction time mean minus median AUC1.62.05.11.40.51.30.91.81.71.81.3-2.30.1-1.81.10.91.4
Reaction time num false alarms0.10.10.60.3-0.30.4-0.00.30.10.40.2-0.80.3-0.80.2-0.00.1
Reaction time num false alarms AUC0.30.40.90.70.31.00.60.60.50.70.7-0.4-0.4-0.10.70.60.7
Reaction time trials correct on left0.10.20.60.00.50.20.60.2-0.00.10.30.7-0.70.80.20.40.2
Reaction time trials on left0.10.10.5-0.10.30.00.40.1-0.1-0.00.20.7-0.60.70.10.30.1
Reaction time mean1.31.85.2-0.9-1.5-1.1-1.6-0.4-0.3-0.4-1.1-1.72.2-2.3-1.2-1.3-1.0
Reaction time mean AUC1.62.15.6-1.0-1.7-1.2-1.8-0.5-0.4-0.4-1.2-1.72.4-2.4-1.3-1.4-1.2
Median of all reaction times2.33.15.8-1.7-2.0-1.9-2.2-1.3-1.2-1.3-1.9-0.82.4-1.6-1.9-1.9-1.9
Reaction time omissions1.31.73.2-1.2-1.5-1.8-1.7-1.2-1.1-1.3-1.4-0.11.5-0.7-1.4-1.5-1.4
Reaction time false alarm rate0.10.10.50.2-0.60.3-0.30.0-0.00.1-0.1-0.60.5-0.70.0-0.2-0.0
Reaction time premature initiation rate2.33.04.9-1.8-1.9-1.8-2.2-1.7-1.0-1.6-2.0-0.42.1-1.3-1.9-1.8-1.8
Reaction time premature initiations1.42.02.8-1.6-1.5-1.6-1.7-1.4-0.9-1.4-1.7-0.11.6-0.8-1.6-1.4-1.4
Std. dev. reaction times0.91.26.60.2-0.70.1-0.60.70.80.7-0.0-2.41.5-2.6-0.1-0.30.1
Reaction time trials completed0.10.10.5-0.10.30.00.40.1-0.1-0.00.20.7-0.60.70.10.30.1
Reaction time trials AUC0.10.10.5-0.00.30.00.40.1-0.10.00.20.6-0.50.70.10.20.1
Social response proportion1.81.93.3-1.3-1.6-1.5-1.7-1.2-0.9-1.2-1.5-0.41.8-1.2-1.5-1.4-1.5
Social responses0.60.81.41.10.80.81.00.91.21.01.0-0.4-0.8-0.01.10.91.0
Social time0.00.00.1-0.2-0.1-0.3-0.2-0.1-0.1-0.2-0.20.20.10.1-0.1-0.1-0.2
Conditioned locomotion0.30.41.8-0.5-0.0-0.5-0.0-0.6-0.6-0.6-0.31.3-0.51.3-0.3-0.1-0.3
Cocaine response after cond. corrected2.42.74.9-1.8-1.0-1.9-1.1-1.9-1.9-1.9-1.42.20.11.8-1.6-1.4-1.6
Cocaine response after cond. not corrected2.12.35.5-1.6-0.8-1.7-0.8-1.7-1.8-1.7-1.22.3-0.22.1-1.3-1.2-1.4
Cocaine response before conditioning0.91.12.01.11.21.41.11.11.21.11.0-0.6-0.8-0.21.21.21.1
Saline control response0.91.23.00.61.30.71.40.70.80.61.01.0-1.71.60.91.20.9
Condit. Reinf. active minus inactive responses0.70.91.30.90.91.01.01.10.91.11.0-0.6-0.7-0.20.91.01.1
Condit. Reinf. active-inactive response ratio0.20.20.40.40.20.30.30.60.40.60.4-0.6-0.0-0.50.30.30.4
Condit. Reinf. active responses2.43.34.71.92.02.22.02.01.82.01.9-0.7-1.60.12.02.02.0
Condit. Reinf. inactive responses3.34.07.02.12.12.62.02.22.12.22.0-1.3-1.4-0.52.22.32.2
Condit. Reinf. lever presses2.53.44.82.11.61.91.72.22.12.21.9-1.8-0.9-1.12.01.92.1
Condit. Reinf. lever reinforcers received2.83.95.52.12.12.32.22.21.92.12.1-0.8-1.70.12.12.22.2
Pavlov. Cond. lever latency2.83.95.4-2.2-1.6-2.2-1.8-2.3-2.3-2.3-2.02.00.91.2-2.1-2.0-2.2
Pavlov. Cond. magazine entry latency0.30.30.7-0.7-0.6-0.4-0.7-0.4-0.4-0.4-0.6-0.30.8-0.6-0.8-0.5-0.5
Pavlov. Cond. change in total contacts1.31.74.81.20.61.30.71.61.51.61.0-2.20.3-1.91.01.11.2
Pavlov. Cond. index score0.50.62.00.60.10.70.30.90.80.90.5-1.40.4-1.30.50.50.6
Pavlov. Cond. latency score0.60.82.60.80.20.90.41.11.01.10.6-1.60.3-1.50.60.60.8
Pavlov. Cond. lever contacts1.42.02.71.61.11.51.31.61.61.71.4-1.3-0.7-0.81.51.41.6
Pavlov. Cond. magazine entry number0.40.52.7-0.20.1-0.50.1-0.7-0.6-0.7-0.11.6-0.81.6-0.0-0.2-0.3
Pavlov. Cond. intertrial magazine entries0.40.50.80.70.90.60.80.60.60.60.80.1-0.80.50.70.70.7
Pavlov. Cond. lever-magazine prob. diff.0.50.62.30.60.10.80.30.90.90.90.4-1.50.4-1.40.40.50.6
Pavlov. Cond. response bias0.71.01.71.10.71.10.71.21.11.20.9-1.3-0.2-1.00.90.91.1
Conditioned reinforcement - actives0.40.41.50.41.01.00.30.40.00.40.4-0.3-0.1-0.20.21.20.8
Conditioned reinforcement - inactives0.10.10.3-0.40.50.4-0.2-0.5-0.5-0.5-0.40.40.10.3-0.40.60.0
Conditioned locomotion0.40.51.80.51.21.00.50.40.10.40.50.0-0.50.20.51.30.9
Intermittent access intake day 1-15 change1.11.12.51.00.71.60.41.11.41.10.8-1.60.1-1.30.81.00.9
Intermittent access intake escalation1.51.53.21.21.01.80.71.41.61.41.1-1.5-0.3-1.11.11.21.2
Intermittent access intake escalation 21.91.94.01.30.91.70.61.51.81.51.1-2.00.1-1.61.11.41.3
Intermitt. access day 1 inactive lever presses0.60.61.30.80.91.10.90.70.90.70.8-0.2-0.80.20.90.80.9
Intermitt. access day 15 inactive lever presses0.10.10.5-0.20.40.20.1-0.30.1-0.3-0.00.6-0.50.70.10.20.0
Intermitt. access escalation Index1.11.02.21.01.10.61.30.71.00.71.00.6-1.51.01.20.80.9
Intermittent access day 1 total infusions0.80.92.4-1.0-0.3-0.8-0.4-1.2-1.5-1.2-0.71.5-0.11.3-0.9-0.6-0.7
Intermittent access day 15 total infusions0.40.41.10.60.91.10.60.50.40.50.6-0.2-0.50.10.60.90.8
Intermittent access terminal intake (last 3 days)0.60.72.00.71.31.20.80.60.50.60.7-0.1-0.70.30.71.41.0
Intermittent access total infusions0.60.71.60.61.21.00.90.50.30.50.80.2-0.90.60.71.31.0
Intermittent access day 1 locomotion1.31.42.9-1.2-1.0-1.3-0.8-1.3-1.7-1.3-1.01.40.31.0-1.2-1.2-1.1
Intermittent access day 15 total locomotion0.80.81.5-1.1-0.8-0.5-1.0-1.1-1.2-1.1-1.00.70.60.3-1.1-0.8-0.9
Intermittent access total locomotion0.50.50.9-0.8-0.8-0.5-0.9-0.8-0.9-0.8-0.80.10.8-0.2-0.9-0.6-0.7
Intermittent access standard deviation0.40.41.10.50.90.80.30.60.80.60.5-0.7-0.2-0.50.51.10.8
Cocaine induced anxiety1.01.11.7-1.3-0.8-1.1-1.2-1.2-1.2-1.2-1.30.60.90.1-1.3-0.9-1.2
Post-drug Anxiety0.40.40.80.60.90.70.80.50.60.50.60.1-0.70.30.70.90.7
Baseline Anxiety1.61.72.71.60.81.41.21.61.61.61.5-1.2-0.7-0.61.41.01.3
Lifetime Intake0.80.92.40.41.50.81.10.1-0.10.10.71.1-1.41.40.61.40.9
Incentive Sensitization - Responses0.20.20.6-0.40.70.3-0.0-0.5-0.4-0.5-0.30.8-0.30.7-0.20.60.0
Incentive Sensitization - Breakpoint0.20.20.6-0.50.50.2-0.1-0.6-0.6-0.6-0.40.8-0.20.7-0.30.5-0.1
Progressive ratio test 1 active lever presses0.50.52.0-0.10.90.20.5-0.4-0.5-0.40.11.3-0.91.40.10.70.3
Progressive ratio test 1 breakpoint0.50.51.90.01.10.40.7-0.2-0.3-0.20.21.2-1.11.40.30.80.5
Progressive ratio test 1 inactive lever presses1.11.14.70.11.30.61.0-0.3-0.4-0.30.31.9-1.72.20.50.80.4
Progressive ratio test 2 active lever presses0.60.62.3-0.50.80.10.2-0.8-1.0-0.8-0.31.5-0.71.5-0.30.50.0
Progressive ratio test 2 breakpoint0.60.72.4-0.70.4-0.2-0.1-1.0-1.2-1.0-0.51.5-0.51.4-0.50.2-0.2
Progressive ratio test 2 inactive lever presses0.30.41.40.21.20.70.50.1-0.20.10.30.4-0.60.50.31.20.6
Total sessions with >9 infusions0.91.04.2-0.60.9-0.20.3-1.0-1.1-1.0-0.32.0-1.02.0-0.30.5-0.0
Short access day 1 total inactive lever presses1.92.25.01.12.21.71.60.91.10.91.20.6-1.81.11.42.11.6
Short access day 10 total inactive lever presses0.30.30.80.50.60.80.40.40.90.40.4-0.3-0.4-0.10.60.80.6
Short access day 1 total infusions1.71.85.10.42.30.81.4-0.00.0-0.00.71.8-2.02.20.91.81.1
Short access day 10 total infusions0.80.93.00.31.40.41.0-0.1-0.2-0.10.51.5-1.51.70.51.10.7
Short access total infusions1.01.14.5-0.21.50.30.7-0.6-0.7-0.60.12.0-1.42.10.21.10.4
Short access day 1 locomotion0.50.51.8-0.70.0-0.5-0.2-0.9-0.9-0.9-0.51.3-0.41.2-0.5-0.2-0.4
Short access day 10 total locomotion0.60.71.3-0.8-1.1-0.9-1.1-0.6-0.9-0.6-0.7-0.31.1-0.7-1.0-0.8-0.8
Short access total locomotion0.30.31.3-0.10.4-0.10.4-0.3-0.5-0.30.01.1-0.71.10.00.40.2
Compulsive drug intake0.30.30.50.70.40.60.70.70.20.70.7-0.1-0.50.20.60.30.5
One hour access (0.3 mA shock)0.50.51.10.60.80.80.90.4-0.40.40.70.7-1.01.00.60.70.8
One hour access (shock baseline)0.40.41.50.20.80.40.7-0.1-0.3-0.10.41.0-1.01.20.30.70.5
Number of responses in last shaping day1.31.36.1-0.21.2-0.30.6-0.7-0.5-0.70.02.3-1.72.50.30.70.2
Context. condit. distance diff. score0.10.10.3-0.3-0.5-0.4-0.5-0.3-0.2-0.3-0.4-0.20.5-0.4-0.4-0.3-0.3
Locomotion velocity, session 12.02.111.70.21.0-0.01.1-0.6-0.3-0.50.62.9-2.43.40.60.40.4
Locomotion distance, session 10.60.83.70.30.70.40.9-0.10.1-0.00.61.5-1.51.90.60.50.5
Locomotion velocity, session 22.42.84.52.11.51.61.61.91.81.91.8-1.3-1.1-0.61.91.61.9
Locomotion distance, session 22.02.84.91.62.01.62.01.41.41.41.80.5-2.21.41.81.91.8
Locomotion velocity, session 30.40.52.7-0.10.4-0.10.4-0.4-0.3-0.40.11.5-1.01.60.10.10.1
Locomotion distance, session 32.02.13.81.31.61.51.81.21.31.21.60.5-2.01.21.61.51.5
Stereotopy head waving bouts, day 30.50.62.5-0.50.1-1.0-0.1-0.8-0.7-0.8-0.31.6-0.61.6-0.3-0.4-0.4
Stereotopy head waving duration, day 30.50.61.4-0.7-0.3-1.2-0.5-0.9-0.8-0.9-0.61.10.00.9-0.7-0.7-0.7
Locomotion velocity, session 70.00.10.1-0.3-0.3-0.2-0.3-0.3-0.2-0.2-0.30.10.2-0.1-0.2-0.2-0.2
Locomotion distance, session 70.20.30.50.60.70.20.60.40.30.40.60.2-0.70.50.60.70.6
Stereotopy head waving bouts, day 71.82.13.01.51.61.41.71.41.51.41.7-0.0-1.70.71.61.51.6
Stereotopy head waving duration, day 70.50.61.20.70.80.71.00.60.70.60.80.3-1.10.70.80.70.8
Locomotion velocity, session 80.20.31.6-0.10.4-0.10.3-0.2-0.2-0.20.11.1-0.81.30.10.10.1
Locomotion distance, session 80.30.41.50.40.50.20.70.10.20.10.50.9-1.11.20.50.60.5
Degree of sensitization distance0.90.91.8-0.8-1.0-1.3-1.2-0.9-1.0-0.9-1.0-0.01.1-0.5-1.0-1.0-1.0
Degree of sensitization stereotypy1.11.21.81.11.11.31.31.11.21.11.2-0.3-1.10.31.21.11.2
Condit. Reinf. active minus inactive responses0.60.61.20.80.71.10.70.90.80.90.8-0.7-0.4-0.40.80.80.8
Condit. Reinf. active-inactive response ratio0.60.61.0-0.9-0.9-0.6-0.9-0.7-0.6-0.6-0.9-0.21.0-0.6-0.9-0.8-0.9
Condit. Reinf. active responses2.93.64.82.11.72.21.92.12.12.12.1-1.3-1.3-0.52.12.02.1
Condit. Reinf. inactive responses3.64.36.02.41.82.22.02.42.42.32.3-1.6-1.3-0.82.32.22.4
Incentive salience index mean4.35.27.82.52.42.82.52.42.32.42.5-0.8-2.10.22.62.52.6
Condit. Reinf. lever presses10.013.417.34.04.04.14.13.53.43.54.1-0.4-3.91.44.24.14.1
Time in familiar zone, hab. session 11.31.26.40.1-1.0-0.4-0.90.20.20.2-0.5-2.11.8-2.5-0.4-0.5-0.3
Time in novel zone, hab. session 12.62.56.8-1.8-0.8-1.3-0.8-1.8-1.9-1.8-1.32.6-0.32.3-1.4-1.3-1.4
Total zone transitions, hab. session 10.00.00.10.3-0.00.10.10.10.10.10.2-0.1-0.0-0.10.20.00.2
Total locomotion distance, hab. session 10.71.02.71.10.30.80.51.11.11.10.8-1.60.2-1.40.80.70.9
Locomotion velocity, hab. session 11.82.63.92.01.21.71.31.81.91.81.7-1.7-0.6-1.11.71.61.8
Time in familiar zone, hab. session 20.80.93.1-0.4-1.1-0.5-1.1-0.4-0.2-0.3-0.8-1.31.6-1.7-0.7-0.7-0.7
Time in novel zone, hab. session 21.91.94.5-1.6-0.8-1.4-0.8-1.6-1.6-1.6-1.22.1-0.11.8-1.3-1.2-1.3
Total zone transitions, hab. session 20.60.71.70.80.90.71.00.50.60.50.90.6-1.31.10.90.80.9
Total locomotion distance, hab. session 20.81.01.51.20.91.01.11.01.11.01.1-0.5-0.90.01.21.21.2
Locomotion velocity, hab. session 21.01.42.11.41.01.21.21.21.31.21.3-0.6-1.0-0.11.31.41.4
Novel to familiar place preference ratio3.73.95.6-2.4-1.6-2.2-1.7-2.1-2.4-2.2-2.02.00.81.3-2.1-2.0-2.2
Novelty place preference4.85.07.2-2.7-1.9-2.4-2.1-2.4-2.6-2.5-2.42.01.21.1-2.5-2.3-2.5
Time in novel zone, NPP test5.86.18.7-2.9-2.1-2.7-2.3-2.7-2.9-2.8-2.62.11.41.2-2.7-2.6-2.8
Total zone transitions, NPP test0.71.02.50.81.11.01.20.50.70.61.10.8-1.61.41.01.01.0
Total locomotion distance, NPP test1.72.44.11.61.71.51.81.11.31.31.70.4-2.01.31.81.71.7
Locomotion velocity, NPP test2.23.24.42.01.91.92.01.51.71.62.00.1-2.11.02.01.92.0
Pavlov. Cond. lever latency7.39.312.5-3.3-3.4-3.5-3.4-3.0-3.0-3.0-3.30.63.1-0.8-3.5-3.5-3.4
Pavlov. Cond. magazine entry latency0.50.60.80.90.80.90.70.80.80.90.8-0.5-0.5-0.20.90.80.9
Pavlov. Cond. change in total contacts2.72.83.81.71.92.01.91.61.71.71.8-0.3-1.70.51.92.01.9
Pavlov. Cond. index score3.34.25.92.32.22.42.22.22.12.22.2-0.9-1.80.02.42.32.3
Pavlov. Cond. latency score3.13.95.62.22.12.42.12.12.02.12.1-0.8-1.70.12.32.22.2
Pavlov. Cond. lever contacts5.36.38.72.72.73.02.72.52.52.62.7-0.7-2.40.52.92.82.8
Pavlov. Cond. magazine entry number0.81.01.4-1.1-1.1-1.2-1.0-1.1-1.1-1.1-1.10.60.70.2-1.2-1.2-1.1
Pavlov. Cond. intertrial magazine entries0.20.30.50.70.50.70.50.60.60.60.6-0.4-0.3-0.20.60.60.6
Pavlov. Cond. lever-magazine prob. diff.3.13.95.42.21.92.32.02.12.12.22.1-1.2-1.5-0.32.22.22.2
Pavlov. Cond. response bias3.23.95.22.22.12.32.12.02.02.02.1-0.7-1.80.22.32.22.3
Bone: apparent density1.22.02.71.51.41.61.51.61.51.61.4-1.0-1.0-0.41.51.61.5
Bone surface0.71.11.71.11.31.01.31.01.01.01.20.0-1.20.51.21.31.1
Bone volume0.61.11.61.11.21.01.21.11.11.11.1-0.4-0.90.11.21.31.1
Bone: connectivity density0.60.91.71.10.81.30.91.11.01.10.9-0.9-0.4-0.61.01.01.0
Bone: cortical apparent density0.40.63.4-0.0-0.40.0-0.50.20.50.2-0.2-1.61.2-1.9-0.20.0-0.1
Bone: cortical area2.43.65.12.01.92.11.82.22.32.22.0-1.5-1.1-0.82.02.11.9
Bone: cortical porosity0.40.50.7-0.7-0.8-0.6-0.8-0.6-0.8-0.6-0.80.20.7-0.1-0.8-0.8-0.7
Bone: cortical porosity0.00.00.0-0.0-0.1-0.0-0.1-0.0-0.2-0.0-0.10.00.00.0-0.1-0.1-0.0
Bone: cortical thickness1.01.63.21.20.91.50.91.51.61.51.0-1.8-0.0-1.51.11.31.1
Bone: cortical thickness0.20.20.6-0.4-0.5-0.2-0.4-0.00.1-0.0-0.4-0.60.7-0.8-0.4-0.3-0.4
Bone: cortical tissue density0.40.53.0-0.1-0.5-0.1-0.60.10.30.1-0.3-1.41.2-1.7-0.3-0.1-0.2
Bone: elastic displacement4.45.07.4-2.4-2.7-2.0-2.6-1.9-1.9-2.0-2.5-0.32.7-1.4-2.5-2.5-2.5
Bone: elastic work2.22.97.5-1.3-1.9-0.8-2.0-0.7-0.7-0.7-1.6-1.82.7-2.7-1.6-1.6-1.5
Bone: endosteal estimation1.02.13.71.41.91.01.81.31.31.41.60.4-1.91.21.61.51.4
Bone: endosteal perimeter1.12.24.51.31.91.11.81.21.21.21.60.8-2.11.51.61.51.4
Bone: final force1.32.23.21.41.71.81.61.71.51.71.5-0.6-1.2-0.01.51.71.5
Bone: final moment1.01.62.41.21.41.51.41.61.41.61.3-0.8-0.9-0.31.31.51.3
Bone: marrow area1.02.23.61.51.91.11.81.51.41.51.70.2-1.91.01.61.51.5
Bone: maximum diameter2.34.35.52.32.42.12.22.32.22.32.3-1.0-1.7-0.12.32.22.2
Bone: maximum force3.05.27.12.42.42.72.42.52.42.62.4-1.2-1.8-0.22.52.52.4
Bone: maximum moment2.34.05.42.12.12.32.12.32.22.32.1-1.3-1.4-0.52.12.22.1
Bone: minimum diameter0.00.10.20.0-0.2-0.4-0.20.00.00.1-0.1-0.40.4-0.5-0.1-0.2-0.1
Bone: periosteal estimation1.53.14.51.82.11.62.01.91.92.02.0-0.5-1.70.31.92.01.8
Bone: periosteal perimeter0.50.91.80.71.30.71.20.70.80.71.00.5-1.31.00.91.00.9
Bone: post-yield work1.52.13.31.51.81.21.71.21.11.31.60.3-1.81.11.61.51.5
Bone: stiffness4.16.48.32.72.72.92.82.82.72.82.7-1.2-2.1-0.12.82.82.7
Bone: tissue strength0.20.20.30.50.40.60.40.60.50.50.5-0.5-0.2-0.40.50.60.5
Bone: trabecular number1.32.02.71.61.31.71.31.61.51.61.4-1.2-0.8-0.71.51.51.5
Bone: trabecular spacing0.10.10.80.1-0.3-0.0-0.20.10.30.1-0.0-0.80.5-0.9-0.00.1-0.0
Bone: trabecular thickness0.10.10.2-0.1-0.4-0.4-0.4-0.2-0.4-0.2-0.3-0.10.4-0.2-0.2-0.4-0.2
Bone: trabecular tissue density2.63.64.62.01.92.02.12.02.12.02.0-0.6-1.80.32.12.12.1
Breakpoint value in progressive ratio session1.01.13.9-0.9-0.2-1.1-0.1-1.2-1.2-1.2-0.62.0-0.61.9-0.5-0.7-0.7
Distance traveled before self-admin4.44.78.32.12.92.02.61.82.01.92.20.3-2.61.22.52.72.4
Distance traveled after self-admin1.01.12.30.91.31.30.71.01.21.10.8-0.9-0.5-0.60.91.51.1
Delta time in closed arm before/after self-admin2.92.84.51.91.12.01.32.12.12.01.8-1.8-0.7-1.11.71.41.7
Delta time in open arm before/after self-admin0.60.61.1-0.9-0.3-0.5-0.5-1.0-1.1-1.0-0.81.00.10.8-0.8-0.5-0.7
Diff in mean of infusions in LGA sessions0.00.00.2-0.1-0.40.0-0.3-0.10.0-0.1-0.2-0.20.3-0.3-0.2-0.2-0.2
Extinction: sum of active levers before priming1.71.72.4-1.6-1.2-1.3-1.5-1.5-1.4-1.5-1.40.71.10.1-1.6-1.3-1.4
Active lever presses in extinction session 60.60.61.3-0.7-0.9-1.0-0.5-0.8-1.1-0.7-0.60.60.40.5-0.7-1.1-0.8
Delta distance traveled before/after self-admin0.40.41.0-0.7-0.5-0.2-1.0-0.6-0.4-0.5-0.8-0.31.0-0.6-0.9-0.4-0.7
Delta ambulatory time before/after self-admin1.21.32.5-1.3-1.0-0.6-1.6-1.1-0.9-1.1-1.4-0.21.5-0.8-1.4-0.9-1.2
Time in closed arm before self-admin2.62.94.4-1.8-1.9-2.1-1.8-1.7-1.9-1.7-1.80.71.6-0.2-1.9-1.9-1.9
Time in closed arm after self-admin0.20.20.6-0.1-0.6-0.5-0.50.00.0-0.0-0.2-0.60.7-0.8-0.3-0.5-0.3
Time in open arm before self-admin2.32.44.31.51.91.52.01.21.21.21.60.5-2.11.21.71.71.6
Time in open arm after self-admin1.21.32.70.91.51.41.50.60.50.61.10.7-1.61.21.11.21.1
Sum of active levers in priming session hrs 5-63.73.65.6-2.1-1.7-2.4-1.7-2.2-2.3-2.1-1.91.61.00.9-2.0-2.1-2.0
Time to tail flick, vehicle, before self-admin1.41.52.7-1.2-1.6-1.3-1.3-1.1-1.2-1.1-1.20.21.3-0.3-1.3-1.6-1.3
Time to tail flick, vehicle, after self-admin0.00.00.1-0.20.2-0.3-0.1-0.2-0.0-0.3-0.10.2-0.10.3-0.10.1-0.1
Time to tail flick, test, before self-admin0.30.30.50.60.30.60.50.70.40.60.5-0.6-0.1-0.50.50.60.6
Time to tail flick, test, after self-admin0.80.81.71.00.50.80.61.20.91.20.9-1.3-0.0-1.00.70.70.9
Delta time to tail flick, vehicle, before/after SA0.30.30.80.40.80.30.50.40.50.40.5-0.1-0.50.10.50.90.6
Delta time to tail flick, test, before/after SA0.10.10.1-0.2-0.3-0.3-0.3-0.20.1-0.1-0.2-0.20.4-0.3-0.2-0.4-0.3
Ambulatory time before self-admin3.23.46.31.62.51.62.31.41.41.41.80.7-2.51.52.02.32.0
Ambulatory time after self-admin0.20.30.80.40.90.70.50.30.40.40.40.1-0.50.20.50.90.6
Total heroin consumption0.80.92.4-1.0-0.4-0.9-0.4-1.3-1.0-1.2-0.81.6-0.31.3-0.7-0.6-0.8
Area under the delay curve0.50.61.1-0.9-0.4-0.4-0.5-0.9-1.0-1.0-0.81.00.10.8-0.8-0.6-0.7
Delay disc. indifference point, 0s delay1.31.42.1-1.3-1.0-1.2-1.1-1.5-1.5-1.5-1.31.20.60.7-1.2-1.2-1.3
Delay disc. indifference point, 16s delay1.51.63.7-1.4-0.6-0.7-0.7-1.7-1.5-1.6-1.31.9-0.01.5-1.1-1.0-1.2
Delay disc. indifference point, 2s delay0.10.10.40.20.10.5-0.00.40.20.30.1-0.60.3-0.60.10.20.2
Delay disc. indifference point, 24s delay0.10.10.1-0.4-0.4-0.2-0.4-0.3-0.3-0.3-0.30.10.3-0.0-0.4-0.4-0.4
Delay disc. indifference point, 4s delay0.10.10.1-0.3-0.2-0.0-0.2-0.3-0.3-0.3-0.30.20.20.1-0.3-0.2-0.3
Delay disc. indifference point, 8s delay0.00.00.20.00.10.50.10.10.10.00.10.1-0.20.20.10.10.1
Delay discount exponential model param0.40.40.90.80.40.30.40.80.90.90.7-1.0-0.0-0.80.70.50.6
Delay discount hyperbolic model param0.40.40.80.70.30.30.40.70.80.80.6-0.9-0.0-0.70.60.50.6
Fecal boli incidents, locomotor time 10.80.91.9-0.8-1.4-0.9-1.1-0.8-0.9-0.8-0.8-0.21.1-0.6-1.0-1.3-0.9
Change in fecal boli incidents, locomotor task1.21.12.21.01.50.61.40.60.70.60.90.8-1.51.21.21.21.0
Time >=10cm from walls, locomotor time 10.20.21.1-0.20.3-0.00.3-0.3-0.2-0.30.01.0-0.71.00.1-0.0-0.1
Bouts of movement, locomotor time 11.51.72.5-1.4-1.5-1.5-1.6-1.3-1.3-1.3-1.50.31.4-0.3-1.4-1.4-1.3
Total resting periods, locomotor time 12.02.23.5-1.5-1.8-1.6-1.9-1.3-1.3-1.3-1.6-0.21.8-0.8-1.7-1.6-1.5
Rest time, locomotor task time 11.92.16.1-0.6-1.8-1.0-1.8-0.3-0.5-0.3-1.0-1.92.4-2.5-1.1-1.3-1.0
Distance moved, locomotor task time 12.02.25.31.11.91.22.00.80.90.81.31.3-2.31.91.51.51.2
Vertical activity count, locomotor time 11.61.75.40.61.40.91.70.30.40.30.81.8-2.22.31.11.10.8
Time >=10cm from walls, locomotor time 20.10.10.20.30.30.50.40.20.20.20.40.1-0.40.30.30.20.3
Bouts of movement, locomotor time 20.60.61.20.80.91.10.80.80.70.80.8-0.3-0.70.10.81.01.0
Total resting periods, locomotor time 20.20.30.60.60.50.80.50.50.40.50.5-0.3-0.3-0.10.50.70.7
Rest time, locomotor task time 20.80.91.5-0.7-1.2-1.2-1.1-0.7-1.0-0.7-1.0-0.21.2-0.6-1.0-1.0-1.0
Distance moved, locomotor task time 20.50.61.20.80.50.80.61.01.11.00.8-0.9-0.3-0.60.80.80.7
Vertical activity count, locomotor time 20.50.50.90.70.70.80.90.70.80.70.80.1-0.90.50.90.80.5
Weight adjusted by age0.30.31.40.10.3-0.10.5-0.2-0.2-0.20.31.1-0.91.20.3-0.10.2
Seeking ratio, delayed vs. immediate footshock3.33.86.32.02.02.51.92.12.32.02.0-1.2-1.5-0.32.12.12.2
Locomotion in novel chamber0.10.20.80.1-0.40.0-0.30.30.00.30.1-0.90.7-0.9-0.1-0.1-0.0
Locomotion in novel chamber post-restriction2.12.54.61.81.01.71.22.01.82.01.5-2.1-0.2-1.61.51.51.5
Progressive ratio0.00.10.1-0.3-0.3-0.4-0.1-0.2-0.3-0.2-0.10.3-0.00.3-0.2-0.3-0.2
Food seeking constrained by brief footshock6.68.113.02.83.62.83.62.32.32.33.00.7-3.62.03.23.23.0
Seeking ratio, punishment vs. effort1.92.34.01.62.01.71.81.31.31.31.50.0-1.70.61.71.91.7
Run reversals in cocaine runway, females0.30.30.90.5-0.40.60.10.50.40.70.4-0.90.4-0.90.2-0.20.1
Run reversals in cocaine runway, males0.00.00.1-0.1-0.3-0.1-0.3-0.10.0-0.1-0.1-0.20.3-0.2-0.2-0.2-0.2
Latency to leave start box in cocaine runway0.70.71.20.91.00.90.81.01.11.00.9-0.7-0.5-0.40.91.00.8
Latency to leave start box in cocaine runway, F0.00.00.0-0.2-0.0-0.1-0.0-0.1-0.1-0.2-0.00.2-0.10.2-0.1-0.2-0.2
Latency to leave start box in cocaine runway, M1.41.32.31.11.51.21.41.01.11.01.10.1-1.40.61.31.41.2
Cd content in liver0.91.01.70.90.80.80.91.31.21.31.0-1.1-0.3-0.80.91.21.0
Co content in liver1.21.42.0-1.4-1.0-1.3-1.0-1.4-1.4-1.4-1.31.10.60.7-1.3-1.2-1.4
Cu content in liver0.81.02.2-0.9-1.3-0.8-1.3-0.7-0.6-0.7-1.1-0.51.5-1.1-1.0-1.0-1.1
Fe content in liver0.70.84.2-0.10.7-0.40.7-0.4-0.4-0.40.21.8-1.42.00.10.30.1
K content in liver0.40.40.9-0.5-0.3-0.6-0.3-0.7-0.7-0.8-0.50.9-0.10.8-0.5-0.5-0.6
Mg content in liver0.60.61.0-0.6-0.9-0.9-0.7-0.8-1.0-0.9-0.70.60.50.3-0.8-0.9-0.8
Mn content in liver0.30.31.00.70.20.50.20.70.60.60.5-1.00.2-0.80.40.30.5
Na content in liver1.21.31.8-1.3-1.2-1.1-1.2-1.3-1.1-1.2-1.30.41.0-0.1-1.2-1.1-1.3
Rb content in liver4.05.07.3-2.7-2.3-2.4-2.2-2.3-2.4-2.2-2.51.21.80.3-2.6-2.4-2.7
Se content in liver2.02.53.92.01.41.81.31.61.81.61.7-1.4-0.8-0.81.71.71.9
Sr content in liver0.60.51.31.10.70.80.70.60.60.60.8-0.4-0.6-0.11.00.60.9
Zn content in liver0.20.31.10.5-0.00.20.00.70.50.60.3-1.10.4-0.90.30.10.2