Hub : Genes

Ppara

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000021463 0.05 0.03 1.3e-04 0.02 0.02 0.02 0.02 4.2e-03 9.3e-04 2.2e-03 1.7e-03
2 Adipose mRNA stability ENSRNOG00000021463 0.36 0.12 0.0e+00 0.23 0.23 0.24 0.24 8.0e-26 1.5e-25 5.2e-26 1.0e-26
3 BLA gene expression ENSRNOG00000021463 0.25 0.12 3.6e-08 0.08 0.13 0.13 0.11 6.3e-05 2.7e-07 1.2e-07 1.2e-06
4 BLA mRNA stability ENSRNOG00000021463 0.16 0.11 1.1e-05 0.1 0.05 0.02 0.07 8.8e-06 1.0e-03 2.2e-02 1.6e-04
5 Brain gene expression ENSRNOG00000021463 0.04 0.03 3.8e-03 0.02 0.01 0.02 0.01 6.7e-03 4.2e-02 6.9e-03 1.7e-02
6 Brain mRNA stability ENSRNOG00000021463 0.07 0.04 1.2e-05 0.05 0.07 0.05 0.05 1.4e-05 3.8e-07 1.8e-05 4.3e-05
7 Eye intron excision ratio chr7:116843283:116843721 0.34 0.15 7.9e-04 0.04 0.04 0.05 0.08 9.7e-02 9.9e-02 5.6e-02 2.3e-02
8 Eye intron excision ratio chr7:116843283:116874471 0.46 0.17 4.1e-05 0.25 0.11 0.23 0.18 1.1e-04 1.0e-02 2.1e-04 9.9e-04
9 Eye intron excision ratio chr7:116843778:116874471 0.77 0.18 8.6e-07 0.25 0.21 0.22 0.25 1.0e-04 3.4e-04 2.6e-04 8.7e-05
10 Eye mRNA stability ENSRNOG00000021463 0.55 0.17 1.3e-05 0.06 0.16 0.16 0.18 4.2e-02 2.1e-03 1.7e-03 1.0e-03
11 Liver gene expression ENSRNOG00000021463 0.58 0.18 5.6e-17 0.11 0.08 0.08 0.12 9.4e-12 1.9e-09 2.2e-09 4.9e-13
12 Liver intron excision ratio chr7:116833786:116874471 0.14 0.07 1.5e-11 0.1 0.1 0.1 0.11 1.5e-11 1.1e-10 2.7e-11 9.0e-12
13 Liver mRNA stability ENSRNOG00000021463 0.3 0.1 0.0e+00 0.27 0.25 0.25 0.24 6.1e-30 5.0e-27 2.8e-27 7.1e-27
14 NAcc mRNA stability ENSRNOG00000021463 0.07 0.04 4.4e-05 0.06 0.04 0.04 0.04 1.3e-05 4.8e-04 1.3e-03 3.0e-04
15 PL mRNA stability ENSRNOG00000021463 0.08 0.06 2.0e-04 0.06 0.04 0.02 0.05 5.1e-05 3.5e-04 6.6e-03 1.4e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail2.37.512.83.5-3.23.43.62.5-1.61.1-0.62.8-3.42.7-1.9-3.21.93.3
BMI without tail1.12.24.90.9-0.91.12.2-0.30.81.8-1.52.2-1.80.40.9-1.42.12.1
Body weight1.25.112.41.9-1.02.03.30.70.72.8-2.43.2-2.31.20.2-1.53.53.2
Epididymis fat weight0.10.31.00.20.00.40.5-0.20.50.9-0.70.7-0.30.20.10.01.00.8
Glucose0.20.30.70.2-0.1-0.3-0.70.4-0.8-0.70.8-0.50.5-0.1-0.50.0-0.0-0.8
Heart weight0.30.51.80.3-0.70.70.11.1-0.8-0.60.3-0.3-0.60.7-0.8-0.6-1.4-0.5
Left kidney weight7.722.044.04.8-3.25.06.63.0-0.44.8-4.76.3-5.94.7-2.7-3.14.66.3
Right kidney weight7.822.240.25.1-3.85.36.33.4-1.24.3-4.16.1-6.15.0-3.1-3.74.16.1
Tail length1.34.09.4-2.32.4-2.1-0.7-2.82.81.6-1.50.31.4-2.33.11.71.6-0.6
Length with tail0.62.16.3-0.81.6-0.80.5-1.52.12.1-2.01.20.3-0.91.71.02.50.7
Length without tail0.40.81.51.2-0.41.00.81.2-0.50.7-0.70.8-0.61.2-1.2-0.51.21.0
Liver weight, left0.20.40.80.8-0.90.80.80.6-0.40.20.10.6-0.90.4-0.2-0.70.30.6
Liver weight, right1.32.14.7-0.81.5-1.10.6-1.32.12.1-1.71.40.2-1.22.01.42.20.5
Parametrial fat weight0.71.34.4-1.31.0-1.2-0.5-1.31.4-0.10.6-0.40.9-2.02.10.10.6-1.0
Retroperitoneal fat weight1.13.68.91.5-0.71.62.60.20.82.7-2.32.9-2.11.0-0.0-0.73.02.4
Intraocular pressure0.91.23.6-0.61.0-0.70.5-1.21.71.3-1.10.70.3-1.41.90.71.70.0
Extensor digitorum longus weight0.21.02.40.7-0.71.11.50.20.31.0-1.01.3-1.20.7-0.1-1.10.91.6
Soleus weight0.41.03.61.2-1.61.20.71.0-0.9-0.20.50.5-1.20.9-1.0-1.90.20.9
Tibialis anterior weight0.10.41.80.1-0.70.5-0.10.6-0.6-0.60.2-0.5-0.30.3-0.6-1.0-1.30.1
Tibia length0.00.10.30.6-0.30.30.10.4-0.3-0.40.4-0.20.10.0-0.3-0.40.60.3
Number of licking bursts0.80.92.0-1.21.2-1.0-0.5-1.31.20.3-0.3-0.30.9-1.31.40.90.3-0.7
Food consumed during 24 hour testing period2.32.85.42.0-1.01.72.30.9-0.41.5-1.52.1-1.92.0-1.0-0.62.12.2
Times rat made contact with spout0.50.61.4-0.20.30.21.0-1.01.11.2-1.21.0-0.70.11.00.01.00.2
Mean time between licks in bursts0.81.22.2-1.41.4-1.1-1.0-1.10.9-0.60.5-1.01.3-1.21.11.5-0.8-0.8
Mean num. licks in bursts0.81.02.31.4-0.91.21.10.9-0.70.5-0.41.0-1.31.5-1.1-0.60.51.1
Std. dev. time between licks in bursts0.60.71.50.6-1.10.6-0.11.0-1.1-1.01.2-0.4-0.20.5-1.0-1.2-0.90.1
Water consumed over 24 hours1.21.42.71.3-0.61.21.60.6-0.21.3-1.31.6-1.41.5-0.7-0.41.31.5
Indifference point 0 sec0.10.10.5-0.1-0.1-0.1-0.2-0.1-0.1-0.40.7-0.40.4-0.60.3-0.50.3-0.2
Indifference point AUC0.20.20.7-0.20.2-0.4-0.70.1-0.1-0.60.8-0.50.5-0.40.20.20.1-0.4
Indifference point function ln k1.11.63.80.70.11.01.8-0.10.81.9-1.91.8-1.00.8-0.00.31.61.6
Indifference point function log k1.11.63.80.70.11.01.8-0.10.81.9-1.91.8-1.00.8-0.00.31.61.6
Delay discounting total patch changes 0 sec0.10.20.6-0.30.1-0.3-0.4-0.2-0.0-0.50.8-0.60.6-0.80.5-0.2-0.0-0.4
Delay discounting total patch changes 12 sec0.10.20.60.4-0.60.30.10.5-0.5-0.10.30.1-0.30.1-0.3-0.80.30.3
Delay discounting total patch changes 18 sec0.60.71.5-0.90.5-1.1-1.1-0.80.3-0.61.0-0.91.1-1.21.00.10.1-0.8
Delay discounting total patch changes 24 sec0.10.10.6-0.40.3-0.3-0.1-0.20.30.00.0-0.20.3-0.80.70.20.2-0.0
Delay discounting total patch changes 6 sec0.30.52.4-0.1-0.3-0.2-0.70.4-0.5-1.31.6-0.90.6-0.90.2-0.6-0.4-0.4
Delay discounting time to switch 0 sec0.20.31.20.3-0.80.1-0.00.3-0.8-0.4-0.1-0.1-0.50.7-1.0-0.7-1.10.0
Delay discounting water rate 0 sec0.20.30.70.7-0.30.70.70.6-0.20.30.20.5-0.40.20.1-0.50.80.6
Delay discounting water rate 12 sec0.50.82.2-0.41.0-0.40.3-0.91.20.60.10.30.6-1.21.50.81.50.4
Delay discounting water rate 18 sec0.10.10.8-0.10.10.00.1-0.40.40.10.2-0.10.4-0.70.5-0.10.90.3
Delay discounting water rate 24 sec0.10.20.50.7-0.40.70.40.6-0.30.3-0.10.4-0.40.2-0.2-0.30.60.6
Delay discounting water rate 6 sec0.81.22.8-1.11.4-1.3-0.7-1.41.20.6-0.1-0.01.2-1.41.71.11.1-0.6
Locomotor activity2.03.29.30.8-0.30.92.3-0.51.22.7-2.43.0-1.80.70.7-0.83.11.9
Locomotor testing distance0.50.82.10.00.20.21.1-0.70.91.4-1.31.3-0.5-0.00.7-0.11.40.8
Locomotor testing rearing0.71.02.70.00.60.41.5-0.71.21.6-1.61.4-0.40.30.50.31.51.0
Light reinforcement 10.71.33.4-0.20.9-0.01.5-0.81.41.8-1.61.3-0.0-0.51.20.51.81.3
Light reinforcement 21.62.15.51.3-0.41.32.30.50.41.8-1.61.9-1.10.9-0.3-0.72.32.2
Reaction time number correct0.30.50.9-0.80.9-0.9-0.6-0.70.5-0.30.5-0.50.9-0.90.90.8-0.1-0.8
Reaction time mean minus median0.30.51.1-0.70.5-1.0-1.0-0.50.4-0.40.3-0.70.8-0.90.70.40.1-0.7
Reaction time mean minus median AUC0.30.31.3-0.60.4-0.9-0.3-0.40.60.2-0.3-0.00.1-0.91.10.10.4-0.7
Reaction time num false alarms1.01.43.0-1.21.6-1.1-0.4-1.51.61.0-0.70.31.0-1.11.31.71.3-0.2
Reaction time num false alarms AUC1.42.04.1-1.42.0-1.3-0.6-1.81.91.4-1.10.41.1-1.11.62.01.5-0.3
Reaction time trials correct on left0.30.50.9-0.80.9-0.9-0.6-0.70.5-0.30.5-0.50.9-0.90.90.8-0.1-0.8
Reaction time trials on left0.40.50.9-0.80.9-0.9-0.6-0.70.5-0.30.5-0.61.0-0.90.90.8-0.1-0.8
Reaction time mean1.21.64.8-0.3-0.4-0.7-1.80.4-1.3-2.01.6-1.90.8-0.3-0.7-0.1-2.2-1.5
Reaction time mean AUC1.21.65.1-0.5-0.2-0.9-1.80.3-1.1-2.01.5-1.90.9-0.5-0.40.0-2.3-1.7
Median of all reaction times1.62.27.2-0.2-0.6-0.5-1.80.6-1.6-2.41.9-2.10.8-0.1-1.1-0.4-2.7-1.6
Reaction time omissions0.60.82.0-0.50.1-0.5-1.30.3-0.6-1.41.2-1.41.0-0.3-0.50.0-1.3-1.1
Reaction time false alarm rate0.70.91.9-0.71.2-0.6-0.2-1.21.41.4-1.20.70.4-0.50.81.31.40.2
Reaction time premature initiation rate2.22.97.22.0-2.71.70.51.9-2.4-0.80.70.1-1.71.9-2.3-2.4-0.80.8
Reaction time premature initiations1.11.53.71.4-1.91.00.11.3-1.9-1.01.0-0.3-1.01.2-1.6-1.7-0.80.2
Std. dev. reaction times0.50.62.1-0.80.4-1.1-1.4-0.4-0.1-0.80.6-1.10.9-0.80.30.4-0.7-1.1
Reaction time trials completed0.40.50.9-0.80.9-0.9-0.6-0.70.5-0.30.5-0.61.0-0.90.90.8-0.1-0.8
Reaction time trials AUC0.20.30.6-0.50.7-0.6-0.3-0.50.4-0.20.4-0.30.7-0.70.80.50.1-0.6
Social response proportion0.60.71.40.9-0.10.91.20.5-0.10.8-0.91.0-0.61.0-0.90.11.01.2
Social responses1.11.44.00.20.80.41.6-0.51.11.8-1.61.5-0.30.20.31.12.01.6
Social time1.01.32.7-1.41.5-1.2-0.8-1.61.50.20.0-0.41.4-1.41.41.20.8-0.4
Conditioned locomotion0.10.10.30.00.40.00.40.10.10.2-0.20.20.10.1-0.10.50.00.4
Cocaine response after cond. corrected0.30.41.1-0.30.4-0.20.2-0.80.80.20.3-0.00.6-1.00.90.51.10.3
Cocaine response after cond. not corrected0.90.92.4-0.91.0-0.7-0.0-1.41.40.4-0.0-0.11.0-1.51.50.91.10.1
Cocaine response before conditioning0.40.51.1-0.90.9-1.0-0.6-0.80.70.2-0.2-0.40.8-0.91.00.7-0.2-0.7
Saline control response0.30.42.2-0.11.1-0.4-0.3-0.00.20.10.1-0.51.3-0.2-0.11.50.30.1
Condit. Reinf. active minus inactive responses0.40.51.31.0-1.10.70.60.5-0.7-0.10.40.4-0.80.6-0.5-1.10.40.0
Condit. Reinf. active-inactive response ratio0.10.10.50.4-0.60.40.30.0-0.3-0.10.30.1-0.40.3-0.1-0.70.1-0.2
Condit. Reinf. active responses1.01.42.81.7-1.61.41.41.0-0.90.4-0.11.1-1.51.2-0.9-1.60.81.0
Condit. Reinf. inactive responses1.62.04.01.8-1.51.71.91.1-0.70.8-0.71.6-1.71.2-1.0-1.41.12.0
Condit. Reinf. lever presses0.50.71.41.0-0.91.11.20.7-0.40.5-0.50.8-1.10.8-0.5-0.90.51.0
Condit. Reinf. lever reinforcers received0.71.02.21.5-1.51.21.10.9-0.90.10.20.8-1.21.0-0.8-1.40.70.8
Pavlov. Cond. lever latency0.20.20.5-0.60.7-0.7-0.6-0.30.3-0.10.0-0.30.6-0.50.40.4-0.1-0.5
Pavlov. Cond. magazine entry latency2.02.35.60.7-1.40.6-1.01.6-2.1-2.32.1-1.70.10.7-1.7-1.2-2.4-1.0
Pavlov. Cond. change in total contacts1.62.25.41.6-2.31.30.41.6-2.2-1.01.2-0.2-1.31.6-1.9-2.2-0.8-0.0
Pavlov. Cond. index score0.71.02.20.9-1.30.8-0.01.1-1.5-1.11.1-0.7-0.40.8-1.2-1.1-1.2-0.3
Pavlov. Cond. latency score1.01.32.81.1-1.51.10.21.4-1.7-1.11.1-0.6-0.61.0-1.5-1.4-1.2-0.1
Pavlov. Cond. lever contacts0.60.91.71.2-1.31.20.81.1-1.1-0.30.20.2-0.91.1-1.3-0.9-0.30.7
Pavlov. Cond. magazine entry number0.91.12.7-0.71.2-0.60.3-1.21.61.1-0.90.80.5-0.91.40.91.60.6
Pavlov. Cond. intertrial magazine entries0.70.91.81.3-1.31.10.71.2-1.0-0.10.20.7-1.10.9-1.1-1.30.30.8
Pavlov. Cond. lever-magazine prob. diff.0.60.71.70.7-1.10.7-0.01.0-1.3-1.00.9-0.6-0.40.7-1.1-0.9-1.2-0.3
Pavlov. Cond. response bias0.70.92.01.1-1.41.10.31.2-1.4-0.80.8-0.3-0.81.0-1.4-1.0-0.90.2
Conditioned reinforcement - actives1.21.22.5-1.21.5-1.1-0.5-1.41.60.7-0.7-0.11.1-1.31.21.20.9-0.4
Conditioned reinforcement - inactives0.20.20.60.00.60.00.2-0.40.50.6-0.60.20.4-0.1-0.10.70.40.5
Conditioned locomotion0.80.93.60.50.10.61.3-0.30.81.3-1.01.3-0.4-0.00.30.11.91.5
Intermittent access intake day 1-15 change0.20.20.7-0.20.5-0.4-0.6-0.60.2-0.00.0-0.40.80.1-0.60.80.20.3
Intermittent access intake escalation0.20.20.7-0.00.6-0.1-0.1-0.60.40.4-0.40.10.50.3-0.60.90.50.6
Intermittent access intake escalation 20.50.51.20.20.1-0.2-0.9-0.3-0.7-1.01.1-0.90.80.3-1.10.4-0.40.4
Intermitt. access day 1 inactive lever presses1.11.23.61.5-1.11.20.81.9-1.8-0.70.70.1-0.91.2-1.3-0.7-0.90.3
Intermitt. access day 15 inactive lever presses2.02.24.62.1-1.52.01.72.0-1.50.00.10.9-1.41.7-1.8-1.30.51.5
Intermitt. access escalation Index0.20.20.60.3-0.20.80.60.40.20.5-0.20.6-0.50.30.2-0.30.30.4
Intermittent access day 1 total infusions1.61.85.30.10.50.41.3-0.71.62.3-2.31.9-0.60.00.50.62.21.2
Intermittent access day 15 total infusions1.11.34.20.10.70.30.9-0.71.31.9-2.11.4-0.20.3-0.10.91.81.3
Intermittent access terminal intake (last 3 days)1.51.64.60.70.20.71.3-0.40.92.0-2.01.8-0.60.7-0.50.32.21.8
Intermittent access total infusions1.61.74.70.60.20.71.4-0.41.12.2-2.21.8-0.70.6-0.30.42.21.7
Intermittent access day 1 locomotion1.31.44.2-0.50.8-0.30.6-1.01.71.8-2.11.3-0.3-0.61.20.81.90.1
Intermittent access day 15 total locomotion1.92.07.1-0.21.0-0.11.0-1.01.82.4-2.71.7-0.4-0.10.61.42.21.0
Intermittent access total locomotion1.01.13.60.40.10.31.0-0.61.01.7-1.91.6-0.80.30.00.31.71.1
Intermittent access standard deviation0.40.41.60.9-0.50.50.20.6-0.80.2-0.10.4-0.41.1-1.3-0.10.30.9
Cocaine induced anxiety2.93.46.22.5-2.42.31.62.3-2.0-0.10.31.3-2.31.9-1.6-2.4-0.21.4
Post-drug Anxiety4.75.210.02.8-2.92.61.33.2-3.1-1.31.30.4-2.22.4-2.6-3.0-1.31.1
Baseline Anxiety0.80.82.0-1.01.0-0.8-1.3-0.60.2-1.00.7-1.41.3-0.4-0.11.0-0.9-0.8
Lifetime Intake1.82.06.00.60.30.61.5-0.51.32.4-2.42.0-0.80.6-0.10.42.41.8
Incentive Sensitization - Responses0.90.92.61.2-0.91.00.21.2-1.2-0.3-0.10.3-1.01.4-1.6-0.8-0.70.4
Incentive Sensitization - Breakpoint0.90.92.51.2-1.01.00.31.2-1.2-0.2-0.20.4-1.11.4-1.6-0.9-0.60.5
Progressive ratio test 1 active lever presses1.61.75.2-0.70.9-0.10.8-1.32.11.9-1.71.4-0.2-0.91.50.62.30.4
Progressive ratio test 1 breakpoint1.51.64.9-0.70.9-0.20.8-1.32.11.8-1.51.3-0.1-1.01.60.62.20.2
Progressive ratio test 1 inactive lever presses0.60.62.2-0.10.50.21.0-0.00.91.4-1.51.2-0.5-0.10.70.50.80.2
Progressive ratio test 2 active lever presses0.10.10.40.4-0.10.30.20.4-0.10.3-0.60.4-0.50.5-0.6-0.10.20.2
Progressive ratio test 2 breakpoint0.20.20.40.5-0.30.40.20.4-0.20.2-0.50.4-0.60.6-0.6-0.20.10.2
Progressive ratio test 2 inactive lever presses0.60.71.30.9-0.10.90.80.8-0.20.9-1.11.0-0.81.1-1.00.20.61.1
Total sessions with >9 infusions2.22.47.4-0.00.80.01.5-1.21.92.6-2.51.9-0.2-0.00.51.02.71.7
Short access day 1 total inactive lever presses1.71.94.81.2-0.51.52.20.60.41.7-1.61.9-1.31.2-0.7-0.21.71.8
Short access day 10 total inactive lever presses0.70.81.91.4-1.00.90.81.4-1.3-0.40.60.3-0.80.9-1.0-0.70.10.7
Short access day 1 total infusions1.81.97.00.00.40.21.4-0.81.62.5-2.71.8-0.70.10.50.52.21.0
Short access day 10 total infusions1.82.07.30.50.40.71.8-0.61.42.3-1.82.0-0.60.10.40.42.71.7
Short access total infusions2.62.97.61.0-0.21.12.2-0.11.12.7-2.62.5-1.30.9-0.2-0.12.82.2
Short access day 1 locomotion0.10.10.30.10.20.00.4-0.30.20.5-0.50.30.10.2-0.50.30.30.3
Short access day 10 total locomotion1.81.94.9-1.21.3-0.90.5-2.02.21.7-1.61.10.2-1.11.71.41.70.3
Short access total locomotion0.90.92.30.50.20.61.4-0.20.81.5-1.41.4-0.60.30.00.31.51.3
Compulsive drug intake0.90.93.50.3-0.80.3-0.40.9-1.4-1.21.2-1.0-0.10.6-1.1-0.8-1.9-0.4
One hour access (0.3 mA shock)0.60.72.2-0.11.0-0.10.5-0.20.91.4-1.50.90.00.10.00.91.10.9
One hour access (shock baseline)1.51.74.9-0.21.4-0.10.9-0.71.62.0-2.11.40.2-0.30.61.42.21.4
Number of responses in last shaping day0.10.10.3-0.10.00.20.30.00.40.6-0.40.5-0.20.2-0.2-0.10.50.1
Context. condit. distance diff. score0.91.15.10.8-0.10.61.00.50.11.6-2.31.4-1.21.2-0.60.20.61.2
Locomotion velocity, session 10.80.92.9-0.10.10.01.0-1.21.31.0-0.81.1-0.5-0.51.1-0.21.71.3
Locomotion distance, session 10.60.81.6-1.21.1-1.1-0.5-1.31.20.1-0.0-0.30.8-1.11.21.00.2-0.0
Locomotion velocity, session 21.82.16.50.7-0.60.82.0-0.71.11.7-1.32.2-1.50.20.7-1.22.62.0
Locomotion distance, session 20.30.51.80.2-0.90.3-0.30.4-0.6-1.11.3-0.5-0.20.2-0.5-1.1-0.8-0.3
Locomotion velocity, session 32.63.17.4-0.81.3-0.71.1-2.02.52.7-2.72.1-0.7-0.52.00.82.41.2
Locomotion distance, session 31.31.43.1-1.31.4-1.3-0.2-1.61.81.1-1.10.30.6-1.11.71.11.0-0.3
Stereotopy head waving bouts, day 30.81.02.50.7-0.80.71.20.00.11.2-1.51.5-1.60.7-0.0-0.90.71.2
Stereotopy head waving duration, day 31.72.04.51.1-0.91.32.10.30.11.6-2.02.0-2.01.2-0.4-0.81.02.1
Locomotion velocity, session 71.31.44.20.00.30.21.4-0.61.21.9-2.11.8-1.10.20.80.11.51.1
Locomotion distance, session 70.20.30.8-0.40.5-0.30.2-0.70.90.8-0.80.5-0.0-0.30.60.30.80.1
Stereotopy head waving bouts, day 70.91.03.80.5-0.10.41.4-0.10.61.5-2.01.5-1.30.60.2-0.00.91.2
Stereotopy head waving duration, day 70.40.52.00.20.10.20.9-0.20.51.0-1.41.0-0.80.30.3-0.00.50.9
Locomotion velocity, session 83.13.87.42.1-1.71.92.41.0-0.41.8-1.92.6-2.72.0-1.1-1.61.92.4
Locomotion distance, session 80.30.52.00.3-0.00.10.5-0.10.41.1-1.41.1-0.90.6-0.0-0.20.80.8
Degree of sensitization distance1.11.12.11.5-1.41.40.91.2-1.10.10.00.8-1.21.3-1.4-1.10.30.8
Degree of sensitization stereotypy0.40.41.70.30.00.30.9-0.10.40.9-1.30.8-0.70.50.10.10.60.8
Condit. Reinf. active minus inactive responses0.30.31.1-0.30.0-0.6-1.1-0.2-0.1-0.60.8-0.50.5-0.70.4-0.00.2-0.8
Condit. Reinf. active-inactive response ratio0.50.62.0-0.70.3-0.9-1.4-0.2-0.2-0.70.6-0.90.8-0.70.30.3-0.6-1.3
Condit. Reinf. active responses1.01.23.0-1.20.8-1.2-1.4-1.10.8-0.60.8-0.91.2-1.71.40.50.1-1.3
Condit. Reinf. inactive responses0.91.02.7-1.21.1-0.9-0.6-1.31.3-0.00.2-0.51.0-1.61.70.90.3-0.7
Incentive salience index mean0.40.51.9-0.50.6-0.6-0.6-0.90.90.30.10.10.6-1.01.10.41.4-0.1
Condit. Reinf. lever presses1.01.45.4-0.51.2-0.40.4-1.31.71.3-0.80.90.5-1.11.60.92.30.9
Time in familiar zone, hab. session 10.70.62.10.8-0.51.11.50.3-0.00.5-0.20.9-0.90.5-0.3-0.50.81.4
Time in novel zone, hab. session 10.10.10.3-0.10.2-0.2-0.50.1-0.20.0-0.4-0.40.30.4-0.40.3-0.5-0.5
Total zone transitions, hab. session 10.91.32.8-1.20.7-1.2-1.7-0.4-0.0-1.10.7-1.71.4-0.90.30.6-1.5-1.5
Total locomotion distance, hab. session 10.30.40.9-0.80.9-0.8-0.2-0.70.90.6-0.70.10.4-0.60.71.00.1-0.1
Locomotion velocity, hab. session 10.30.51.1-0.80.9-0.9-0.2-0.91.00.6-0.70.20.3-0.70.91.00.40.0
Time in familiar zone, hab. session 20.60.71.8-0.71.3-0.40.1-1.01.30.6-0.50.20.8-0.50.81.30.90.3
Time in novel zone, hab. session 20.40.41.10.1-0.5-0.2-0.70.5-0.9-0.70.5-0.70.00.0-0.5-0.4-1.0-0.9
Total zone transitions, hab. session 20.50.71.50.9-1.11.00.51.1-1.0-0.50.50.0-0.71.0-1.2-0.8-0.50.7
Total locomotion distance, hab. session 20.10.10.30.4-0.20.30.30.3-0.20.10.00.4-0.40.5-0.4-0.10.20.4
Locomotion velocity, hab. session 20.10.10.20.3-0.20.20.30.3-0.10.10.10.4-0.40.5-0.3-0.20.20.4
Novel to familiar place preference ratio0.20.20.7-0.60.5-0.5-0.3-0.60.3-0.2-0.2-0.50.4-0.20.40.9-0.7-0.3
Novelty place preference0.30.31.4-0.60.7-0.5-0.1-0.70.60.3-0.7-0.10.3-0.10.51.2-0.3-0.0
Time in novel zone, NPP test0.30.41.7-0.70.8-0.5-0.1-0.80.60.3-0.7-0.20.4-0.10.61.3-0.5-0.0
Total zone transitions, NPP test0.50.81.8-0.80.6-0.8-1.1-0.0-0.1-1.21.1-1.31.0-0.70.10.5-1.3-0.9
Total locomotion distance, NPP test0.10.20.4-0.40.5-0.6-0.4-0.20.2-0.40.5-0.30.5-0.40.20.6-0.4-0.4
Locomotion velocity, NPP test0.20.20.5-0.60.6-0.7-0.4-0.30.3-0.40.6-0.40.5-0.50.40.6-0.3-0.4
Pavlov. Cond. lever latency0.60.82.70.4-1.10.5-0.11.2-1.2-0.60.2-0.2-0.81.0-1.2-1.1-1.7-0.5
Pavlov. Cond. magazine entry latency0.30.42.2-0.20.0-0.3-0.8-0.3-0.2-1.01.5-1.00.9-0.40.1-0.20.1-0.6
Pavlov. Cond. change in total contacts0.30.31.20.5-0.60.4-0.10.2-0.5-0.71.1-0.40.3-0.1-0.3-0.70.8-0.0
Pavlov. Cond. index score0.20.20.8-0.00.2-0.2-0.3-0.50.2-0.40.9-0.40.8-0.50.30.10.9-0.1
Pavlov. Cond. latency score0.10.21.10.00.3-0.2-0.1-0.50.3-0.10.5-0.10.6-0.40.40.31.00.2
Pavlov. Cond. lever contacts1.01.25.0-0.41.2-0.50.2-1.31.50.9-0.40.50.8-1.11.41.22.20.6
Pavlov. Cond. magazine entry number0.30.31.70.1-0.10.30.60.30.10.8-1.30.8-0.90.4-0.10.1-0.40.4
Pavlov. Cond. intertrial magazine entries0.60.72.0-0.80.5-0.7-1.4-0.20.0-0.90.9-1.21.2-1.10.50.4-0.7-1.1
Pavlov. Cond. lever-magazine prob. diff.0.30.30.9-0.30.4-0.4-0.5-0.70.4-0.30.9-0.50.9-0.80.60.30.9-0.3
Pavlov. Cond. response bias0.40.52.2-0.30.6-0.4-0.2-1.00.8-0.10.8-0.31.0-1.00.90.41.50.1
Bone: apparent density0.50.82.1-0.70.1-0.6-1.2-0.4-0.1-1.20.9-1.40.9-0.80.40.0-1.1-1.3
Bone surface0.10.30.6-0.5-0.2-0.3-0.6-0.50.1-0.70.4-0.80.4-0.40.4-0.6-0.6-0.7
Bone volume0.20.41.0-0.70.1-0.6-0.8-0.60.2-0.70.4-1.00.7-0.70.6-0.1-0.7-0.9
Bone: connectivity density0.30.51.2-0.80.2-0.7-0.8-0.90.4-0.50.4-0.80.6-1.00.90.0-0.5-1.1
Bone: cortical apparent density0.40.61.4-0.50.2-0.7-1.20.1-0.5-0.90.7-1.10.8-0.1-0.40.2-1.2-1.2
Bone: cortical area0.91.42.61.6-1.01.51.31.3-0.80.8-0.61.2-1.21.6-1.3-0.70.81.5
Bone: cortical porosity0.70.71.91.4-0.91.00.61.0-0.90.4-0.10.6-0.61.0-1.1-0.60.90.9
Bone: cortical porosity0.80.82.01.4-1.01.10.71.1-0.90.3-0.00.6-0.71.1-1.1-0.70.90.9
Bone: cortical thickness0.30.51.50.8-0.60.6-0.21.2-1.2-0.40.5-0.2-0.10.9-1.2-0.2-0.40.1
Bone: cortical thickness1.92.24.82.0-1.41.81.31.9-1.50.5-0.41.3-1.52.2-2.1-1.00.51.4
Bone: cortical tissue density0.30.41.1-0.40.2-0.6-1.00.2-0.5-0.80.6-0.90.6-0.0-0.40.2-1.0-1.0
Bone: elastic displacement0.40.51.4-0.20.7-0.40.3-0.70.90.8-0.30.60.2-0.60.90.91.20.8
Bone: elastic work1.92.55.11.9-1.31.71.91.1-0.61.4-1.02.0-1.91.7-1.1-0.91.62.2
Bone: endosteal estimation1.32.75.81.6-1.11.82.40.70.11.8-1.92.2-2.11.4-0.6-1.41.62.3
Bone: endosteal perimeter1.53.16.71.6-0.71.72.60.60.42.3-2.02.5-1.91.4-0.5-0.82.32.6
Bone: final force1.72.85.92.2-2.02.11.12.4-2.0-0.30.10.4-1.42.1-2.3-1.9-0.41.4
Bone: final moment2.23.67.12.4-2.32.41.32.7-2.2-0.30.20.6-1.72.4-2.7-2.0-0.41.7
Bone: marrow area1.22.75.71.6-1.11.82.40.70.11.7-1.82.1-2.11.4-0.6-1.41.52.3
Bone: maximum diameter3.46.211.82.8-1.92.93.31.6-0.52.3-2.13.2-3.02.6-1.7-1.82.53.4
Bone: maximum force2.44.18.12.6-2.52.51.42.8-2.4-0.20.10.8-2.02.5-2.7-2.4-0.41.8
Bone: maximum moment2.95.19.32.9-2.82.81.63.0-2.6-0.30.20.9-2.22.9-3.0-2.5-0.42.0
Bone: minimum diameter0.71.33.60.80.20.71.50.00.71.8-1.61.7-0.80.70.10.31.91.5
Bone: periosteal estimation1.53.15.82.0-1.42.12.41.3-0.41.6-1.62.2-2.11.9-1.2-1.41.52.4
Bone: periosteal perimeter2.03.27.11.6-0.71.62.50.50.52.4-1.92.6-1.81.5-0.5-0.72.72.6
Bone: post-yield work1.11.54.50.6-1.60.9-0.21.3-1.5-1.51.2-1.0-0.50.7-1.2-2.1-1.7-0.5
Bone: stiffness3.04.811.32.2-2.62.00.13.2-3.4-2.01.5-1.0-1.12.4-3.2-2.3-2.30.1
Bone: tissue strength1.41.43.00.9-1.30.8-0.41.5-1.7-1.71.7-1.0-0.20.7-1.5-1.1-1.30.0
Bone: trabecular number0.91.42.3-1.41.1-1.4-1.3-1.40.9-0.50.4-1.21.4-1.51.41.0-0.4-1.3
Bone: trabecular spacing2.83.67.32.0-1.82.22.71.3-0.61.3-1.22.3-2.61.9-1.2-2.01.42.3
Bone: trabecular thickness0.30.30.9-0.70.7-0.8-1.0-0.50.40.2-0.4-0.40.6-0.40.50.8-0.1-0.5
Bone: trabecular tissue density0.81.13.6-0.0-0.7-0.3-1.20.6-1.3-1.51.1-1.20.20.5-0.9-0.8-1.9-1.3
Breakpoint value in progressive ratio session0.70.82.00.8-0.80.40.21.1-1.4-1.20.9-0.6-0.40.6-0.9-0.9-1.4-0.3
Distance traveled before self-admin0.40.41.1-0.30.5-0.20.3-0.50.90.9-1.00.7-0.1-0.40.90.40.80.1
Distance traveled after self-admin0.40.51.10.9-0.50.80.90.6-0.40.3-0.40.7-0.60.9-0.6-0.70.41.0
Delta time in closed arm before/after self-admin0.40.41.50.6-0.80.90.40.5-0.8-0.40.30.1-0.50.8-1.2-0.6-0.30.7
Delta time in open arm before/after self-admin1.71.63.2-1.31.7-1.4-0.3-1.41.81.4-1.40.40.8-1.11.71.60.9-0.1
Diff in mean of infusions in LGA sessions1.01.12.81.3-1.31.10.31.5-1.7-1.11.0-0.3-0.70.9-1.3-0.7-0.90.1
Extinction: sum of active levers before priming0.70.72.20.4-0.90.5-0.40.4-1.0-1.31.5-0.8-0.00.1-0.6-1.1-1.2-0.1
Active lever presses in extinction session 62.01.94.51.8-1.61.71.51.5-1.5-0.50.40.7-1.61.4-1.2-2.1-0.41.0
Delta distance traveled before/after self-admin0.20.20.90.4-0.00.40.90.10.10.5-0.50.6-0.30.5-0.2-0.30.40.9
Delta ambulatory time before/after self-admin0.20.31.00.6-0.20.70.80.4-0.20.1-0.20.3-0.30.8-0.6-0.40.21.0
Time in closed arm before self-admin0.80.92.8-0.1-0.0-0.3-1.40.3-0.9-1.51.6-1.71.1-0.2-0.70.0-1.2-0.7
Time in closed arm after self-admin0.10.10.80.10.10.4-0.20.0-0.2-0.1-0.0-0.20.20.4-0.90.2-0.00.6
Time in open arm before self-admin0.50.51.8-0.80.5-0.50.4-0.61.00.6-0.70.5-0.1-0.81.30.30.5-0.8
Time in open arm after self-admin0.30.31.8-0.50.5-0.70.2-0.20.60.5-0.50.4-0.1-0.71.30.3-0.0-0.8
Sum of active levers in priming session hrs 5-61.00.92.01.0-1.30.80.40.8-1.4-0.90.6-0.2-0.81.0-1.3-1.2-1.20.3
Time to tail flick, vehicle, before self-admin0.30.31.0-0.60.4-0.3-0.1-0.30.80.5-0.50.3-0.1-0.71.00.20.2-0.6
Time to tail flick, vehicle, after self-admin0.10.20.4-0.20.1-0.10.0-0.50.70.5-0.50.20.1-0.50.50.20.50.4
Time to tail flick, test, before self-admin1.11.14.0-0.10.6-0.00.8-0.71.41.8-1.61.3-0.30.10.50.82.01.1
Time to tail flick, test, after self-admin0.50.51.70.3-0.20.6-0.60.2-0.8-1.11.1-0.90.50.6-1.30.1-0.70.2
Delta time to tail flick, vehicle, before/after SA0.80.81.71.1-1.31.00.50.9-1.1-0.30.30.3-1.01.0-1.1-1.3-0.20.9
Delta time to tail flick, test, before/after SA2.11.85.30.1-0.4-0.0-1.50.5-1.6-2.32.2-2.01.0-0.0-1.1-0.3-2.2-1.1
Ambulatory time before self-admin0.40.51.2-0.50.7-0.50.1-0.71.00.9-1.00.60.1-0.51.10.70.6-0.2
Ambulatory time after self-admin0.10.10.40.3-0.00.40.20.2-0.3-0.20.10.00.00.5-0.50.0-0.20.6
Total heroin consumption1.41.73.51.7-1.21.51.11.9-1.9-1.00.90.1-1.11.4-1.6-1.5-0.80.5
Area under the delay curve2.12.35.6-1.1-0.1-1.2-2.00.0-0.4-2.12.4-2.01.0-1.61.1-0.2-1.9-2.3
Delay disc. indifference point, 0s delay0.10.10.50.1-0.40.0-0.20.3-0.0-0.10.30.3-0.4-0.30.6-0.7-0.1-0.0
Delay disc. indifference point, 16s delay2.22.35.3-1.20.1-1.1-1.9-0.2-0.5-2.22.3-2.21.3-1.40.60.3-2.0-1.9
Delay disc. indifference point, 2s delay0.30.41.4-0.2-0.4-0.2-0.90.3-0.5-0.91.2-0.60.1-0.50.3-0.4-0.9-0.5
Delay disc. indifference point, 24s delay0.60.62.60.7-1.10.5-0.20.9-1.1-1.11.6-0.5-0.40.1-0.3-0.6-0.3-0.1
Delay disc. indifference point, 4s delay2.22.35.8-1.0-0.3-0.9-1.80.4-0.7-2.12.4-1.80.7-1.51.1-0.7-2.3-2.4
Delay disc. indifference point, 8s delay1.91.95.9-1.0-0.2-1.0-1.70.1-0.5-1.92.0-1.90.8-1.30.9-0.5-1.9-2.4
Delay discount exponential model param2.32.46.01.20.11.22.00.10.42.1-2.52.0-1.01.7-1.30.21.82.4
Delay discount hyperbolic model param2.02.15.41.10.21.21.9-0.00.42.0-2.31.8-0.91.7-1.20.31.72.2
Fecal boli incidents, locomotor time 10.10.10.50.3-0.20.20.60.4-0.00.1-0.10.4-0.60.4-0.1-0.70.10.2
Change in fecal boli incidents, locomotor task0.60.61.4-0.81.1-0.9-0.5-1.00.70.10.0-0.41.0-0.90.81.20.4-0.6
Time >=10cm from walls, locomotor time 10.80.82.00.8-1.21.11.10.6-0.60.1-0.00.6-1.21.1-0.9-1.4-0.10.9
Bouts of movement, locomotor time 10.60.62.40.9-1.31.10.50.5-0.5-0.10.10.4-1.00.8-0.8-1.50.20.3
Total resting periods, locomotor time 11.01.13.01.2-1.61.40.51.0-1.2-0.80.8-0.0-0.91.0-1.3-1.7-0.50.1
Rest time, locomotor task time 10.60.61.60.8-1.21.11.10.4-0.20.20.20.9-1.30.3-0.1-1.20.30.7
Distance moved, locomotor task time 10.10.10.30.30.1-0.00.30.4-0.10.4-0.60.3-0.20.20.0-0.10.30.3
Vertical activity count, locomotor time 10.20.20.60.4-0.10.20.10.5-0.7-0.50.5-0.40.10.6-0.8-0.3-0.40.3
Time >=10cm from walls, locomotor time 20.80.92.51.1-0.71.20.80.7-1.0-0.50.80.3-0.51.2-1.4-0.6-0.11.6
Bouts of movement, locomotor time 21.11.23.10.4-1.40.4-1.11.2-1.4-1.41.2-1.0-0.40.3-0.8-1.8-1.3-1.0
Total resting periods, locomotor time 21.21.23.50.3-1.40.3-1.21.0-1.3-1.51.4-1.1-0.30.1-0.6-1.9-1.3-1.1
Rest time, locomotor task time 22.52.96.9-2.21.1-1.9-1.5-2.11.8-0.61.0-1.21.5-2.62.60.30.2-2.1
Distance moved, locomotor task time 21.82.15.71.7-0.51.41.91.1-0.61.5-1.71.9-1.41.8-1.3-0.01.02.4
Vertical activity count, locomotor time 22.22.47.02.0-0.61.61.91.6-1.01.1-1.11.7-1.52.1-1.6-0.50.82.6
Weight adjusted by age1.41.64.41.4-1.01.41.70.7-0.31.3-0.81.5-1.21.2-1.0-1.11.32.1
Seeking ratio, delayed vs. immediate footshock0.70.82.5-0.50.2-0.4-0.90.1-0.5-1.41.0-1.41.0-0.3-0.40.8-1.6-1.1
Locomotion in novel chamber2.73.37.1-2.12.4-1.8-0.3-2.02.71.7-1.50.21.5-2.02.62.11.4-0.7
Locomotion in novel chamber post-restriction0.10.10.30.2-0.30.50.40.5-0.3-0.10.00.1-0.40.2-0.2-0.4-0.50.5
Progressive ratio0.30.30.7-0.60.5-0.7-0.8-0.70.3-0.30.3-0.30.5-0.80.80.4-0.2-0.9
Food seeking constrained by brief footshock0.40.51.21.1-0.31.11.10.7-0.50.4-0.20.7-0.60.9-0.80.00.50.9
Seeking ratio, punishment vs. effort1.41.73.41.7-1.21.81.41.7-1.4-0.10.10.4-1.11.7-1.9-1.0-0.21.4
Run reversals in cocaine runway, females1.21.22.4-1.31.5-1.1-0.4-1.31.50.7-0.6-0.11.2-1.21.11.40.9-0.2
Run reversals in cocaine runway, males1.31.33.2-0.80.8-0.70.5-1.41.81.8-1.41.2-0.2-0.61.31.01.40.5
Latency to leave start box in cocaine runway1.01.12.31.0-0.31.11.40.50.11.3-1.41.5-1.20.9-0.5-0.01.21.1
Latency to leave start box in cocaine runway, F0.50.61.60.5-0.20.81.00.20.31.0-1.31.0-0.80.6-0.20.10.71.0
Latency to leave start box in cocaine runway, M0.90.81.71.2-0.31.01.20.6-0.31.0-0.91.3-0.91.0-0.7-0.41.20.8
Cd content in liver0.20.20.4-0.0-0.0-0.0-0.50.3-0.5-0.60.6-0.70.6-0.1-0.5-0.1-0.6-0.5
Co content in liver0.50.51.70.20.50.31.0-0.40.61.1-1.00.9-0.30.10.50.61.30.9
Cu content in liver3.34.09.1-1.80.9-1.7-2.6-0.3-0.3-2.62.4-3.02.2-1.80.60.6-2.9-2.4
Fe content in liver0.10.10.40.50.10.20.10.1-0.3-0.40.60.1-0.00.4-0.10.10.30.3
K content in liver0.70.72.00.8-0.80.5-0.31.4-1.2-0.90.9-0.5-0.20.6-1.2-0.7-0.70.2
Mg content in liver0.90.91.80.8-1.10.6-0.41.3-1.4-1.31.3-0.8-0.20.5-1.2-1.2-0.8-0.1
Mn content in liver0.80.93.00.00.5-0.00.8-0.41.11.5-1.41.2-0.30.00.50.81.71.4
Na content in liver1.51.63.5-0.7-0.2-0.9-1.80.3-0.8-1.91.8-1.91.0-0.4-0.3-0.2-1.8-1.8
Rb content in liver0.60.82.10.3-0.50.5-0.51.0-1.2-1.41.2-1.00.10.4-0.9-0.7-1.5-0.2
Se content in liver0.50.51.4-0.71.0-0.8-0.4-0.70.90.1-0.0-0.41.0-1.10.81.20.4-0.2
Sr content in liver1.61.42.7-1.61.2-1.5-0.7-1.61.60.4-0.6-0.51.2-1.61.51.20.2-1.0
Zn content in liver1.01.12.1-1.21.2-1.3-1.0-0.90.7-0.30.1-1.21.4-1.51.01.3-0.5-0.9