Hub : Genes

AABR07073181.1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000021437 0.06 0.04 3.2e-09 0.09 0.08 0.07 0.08 4.5e-10 2.1e-09 9.9e-09 2.0e-09
2 Adipose isoform ratio ENSRNOT00000039341 0.02 0.01 6.5e-03 0 0.01 -0 0 2.1e-01 2.6e-02 3.8e-01 3.1e-01
3 Adipose isoform ratio ENSRNOT00000098496 0.22 0.1 0.0e+00 0.33 0.33 0.32 0.33 3.4e-37 3.6e-37 7.3e-37 3.1e-37
4 Adipose isoform ratio ENSRNOT00000105209 0.23 0.1 0.0e+00 0.35 0.36 0.36 0.36 1.3e-40 6.4e-42 1.1e-41 2.2e-41
5 Adipose intron excision ratio chr5:149716950:149718780 0.18 0.08 0.0e+00 0.22 0.23 0.23 0.22 1.3e-23 6.6e-25 9.4e-25 6.6e-24
6 Adipose intron excision ratio chr5:149716950:149719207 0.26 0.1 0.0e+00 0.36 0.37 0.37 0.37 3.5e-42 1.1e-43 1.2e-43 4.4e-43
7 Adipose intron excision ratio chr5:149718830:149719207 0.22 0.1 0.0e+00 0.32 0.31 0.32 0.31 5.0e-36 1.8e-35 8.5e-36 2.1e-35
8 Liver gene expression ENSRNOG00000021437 0.04 0.03 2.2e-04 0.03 0.01 0.02 0.02 7.2e-04 9.7e-03 4.0e-03 5.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.00.00.10.3-0.30.30.00.1-0.10.30.3
BMI without tail0.30.60.70.80.70.8-0.80.7-0.70.80.9
Body weight1.98.18.62.82.92.9-2.92.7-2.82.82.8
Epididymis fat weight0.00.00.0-0.2-0.1-0.20.1-0.00.1-0.2-0.2
Glucose3.85.97.32.52.02.5-2.32.7-2.52.52.4
Heart weight1.62.33.21.51.21.8-1.41.7-1.61.51.5
Left kidney weight9.627.527.85.35.25.3-5.35.2-5.25.35.3
Right kidney weight5.014.214.83.73.83.8-3.83.8-3.83.73.7
Tail length1.85.48.02.22.82.1-2.52.2-2.42.22.2
Length with tail2.910.512.83.13.63.2-3.43.2-3.33.13.1
Length without tail1.43.13.51.71.81.9-1.81.7-1.81.71.7
Liver weight, left2.94.66.72.02.62.1-2.32.0-2.12.02.1
Liver weight, right2.44.04.72.02.22.0-2.01.8-2.02.02.0
Parametrial fat weight0.00.00.1-0.2-0.3-0.40.2-0.10.2-0.2-0.2
Retroperitoneal fat weight0.41.21.7-1.1-1.3-1.11.1-0.91.0-1.1-1.0
Intraocular pressure0.00.00.20.20.20.5-0.20.0-0.10.20.2
Extensor digitorum longus weight0.31.01.5-0.9-1.0-1.01.0-1.21.1-0.9-0.9
Soleus weight0.31.01.9-0.9-0.7-1.00.9-1.41.1-0.9-0.9
Tibialis anterior weight0.10.20.6-0.3-0.5-0.40.5-0.80.6-0.3-0.4
Tibia length0.41.11.81.01.30.9-1.10.8-1.01.01.0
Number of licking bursts0.00.00.10.20.00.1-0.10.3-0.20.20.1
Food consumed during 24 hour testing period1.11.41.61.21.01.2-1.11.3-1.21.21.2
Times rat made contact with spout0.40.50.50.70.50.7-0.60.7-0.70.70.7
Mean time between licks in bursts0.71.01.2-1.0-0.9-1.11.0-1.01.0-1.0-0.9
Mean num. licks in bursts0.30.30.40.50.60.6-0.60.5-0.50.50.6
Std. dev. time between licks in bursts0.10.10.3-0.3-0.2-0.40.3-0.50.4-0.3-0.3
Water consumed over 24 hours0.00.00.0-0.1-0.1-0.20.1-0.10.1-0.1-0.1
Indifference point 0 sec0.10.10.30.40.20.5-0.2-0.0-0.10.40.3
Indifference point AUC1.41.62.21.51.11.2-1.21.1-1.21.51.4
Indifference point function ln k4.76.77.4-2.7-2.3-2.72.6-2.62.6-2.7-2.5
Indifference point function log k4.76.77.4-2.7-2.3-2.72.6-2.62.6-2.7-2.5
Delay discounting total patch changes 0 sec0.00.00.10.20.00.30.0-0.30.10.20.1
Delay discounting total patch changes 12 sec1.92.53.01.71.61.7-1.51.3-1.41.71.6
Delay discounting total patch changes 18 sec1.11.51.91.41.21.3-1.20.9-1.11.41.2
Delay discounting total patch changes 24 sec1.01.31.81.30.81.3-1.00.9-1.01.31.2
Delay discounting total patch changes 6 sec3.04.55.62.41.82.4-2.01.8-1.92.42.3
Delay discounting time to switch 0 sec1.31.92.31.31.41.4-1.41.5-1.51.31.3
Delay discounting water rate 0 sec2.03.23.6-1.7-1.9-1.71.9-1.81.8-1.7-1.7
Delay discounting water rate 12 sec2.13.13.6-1.6-1.9-1.71.9-1.91.9-1.6-1.6
Delay discounting water rate 18 sec1.62.12.9-1.6-0.9-1.51.3-1.71.5-1.6-1.5
Delay discounting water rate 24 sec2.83.94.4-2.1-1.8-1.91.9-2.02.0-2.1-2.1
Delay discounting water rate 6 sec3.65.25.4-2.3-2.3-2.32.3-2.32.3-2.3-2.3
Locomotor activity0.81.21.91.01.21.4-1.10.9-1.01.01.0
Locomotor testing distance0.30.50.90.60.81.0-0.80.6-0.70.60.6
Locomotor testing rearing0.40.61.00.80.91.0-0.80.6-0.70.80.7
Light reinforcement 10.30.60.70.90.60.8-0.70.6-0.70.90.8
Light reinforcement 20.00.00.1-0.0-0.4-0.20.2-0.20.2-0.0-0.0
Reaction time number correct0.91.21.4-1.2-1.1-1.01.1-1.01.1-1.2-1.1
Reaction time mean minus median1.01.41.61.30.71.2-1.01.3-1.21.31.3
Reaction time mean minus median AUC2.53.23.71.91.31.8-1.71.9-1.81.91.9
Reaction time num false alarms0.00.00.10.10.10.3-0.10.1-0.10.10.1
Reaction time num false alarms AUC0.10.10.1-0.3-0.3-0.10.3-0.30.3-0.3-0.4
Reaction time trials correct on left0.91.21.4-1.2-1.1-1.01.1-1.01.1-1.2-1.1
Reaction time trials on left0.91.31.5-1.2-1.1-1.11.1-1.01.1-1.2-1.2
Reaction time mean0.20.30.30.50.50.5-0.50.5-0.50.50.5
Reaction time mean AUC0.00.00.00.10.10.1-0.10.2-0.10.10.1
Median of all reaction times0.00.00.0-0.10.1-0.1-0.0-0.0-0.0-0.1-0.1
Reaction time omissions0.00.00.0-0.1-0.1-0.10.1-0.10.1-0.1-0.1
Reaction time false alarm rate0.00.10.20.20.30.4-0.30.2-0.20.20.2
Reaction time premature initiation rate1.01.41.5-1.1-1.2-1.21.2-1.21.2-1.1-1.1
Reaction time premature initiations1.92.72.8-1.6-1.7-1.71.7-1.61.7-1.6-1.6
Std. dev. reaction times0.30.40.60.70.40.7-0.60.8-0.70.70.7
Reaction time trials completed0.91.31.5-1.2-1.1-1.11.1-1.01.1-1.2-1.2
Reaction time trials AUC0.60.81.0-1.0-0.9-0.90.9-0.80.9-1.0-0.9
Social response proportion0.00.00.0-0.0-0.10.20.00.1-0.0-0.00.1
Social responses0.10.10.20.20.20.5-0.20.1-0.20.20.3
Social time0.30.30.4-0.6-0.4-0.60.5-0.60.6-0.6-0.6
Conditioned locomotion1.51.82.1-1.3-1.5-1.41.4-1.21.3-1.3-1.3
Cocaine response after cond. corrected0.00.10.2-0.2-0.4-0.30.20.10.0-0.2-0.2
Cocaine response after cond. not corrected0.00.10.20.1-0.00.2-0.20.5-0.30.10.1
Cocaine response before conditioning1.21.52.01.11.41.4-1.31.1-1.21.11.1
Saline control response0.00.10.2-0.1-0.5-0.10.3-0.20.2-0.1-0.1
Condit. Reinf. active minus inactive responses0.20.20.4-0.4-0.6-0.40.5-0.60.6-0.4-0.4
Condit. Reinf. active-inactive response ratio0.91.01.3-1.0-1.2-1.01.0-0.90.9-1.0-0.9
Condit. Reinf. active responses0.00.00.10.10.20.2-0.1-0.20.00.10.2
Condit. Reinf. inactive responses0.91.12.21.01.51.1-1.10.6-0.81.01.0
Condit. Reinf. lever presses0.70.91.7-1.0-0.5-0.90.8-1.31.1-1.0-0.9
Condit. Reinf. lever reinforcers received0.00.00.10.10.30.2-0.1-0.30.10.10.1
Pavlov. Cond. lever latency0.20.20.60.50.20.3-0.40.8-0.60.50.5
Pavlov. Cond. magazine entry latency2.02.32.6-1.6-1.3-1.61.5-1.61.5-1.6-1.6
Pavlov. Cond. change in total contacts0.20.30.7-0.6-0.1-0.40.4-0.80.6-0.6-0.6
Pavlov. Cond. index score1.21.52.1-1.3-0.9-1.11.2-1.51.3-1.3-1.3
Pavlov. Cond. latency score1.41.82.4-1.4-1.1-1.21.3-1.51.4-1.4-1.4
Pavlov. Cond. lever contacts0.00.10.2-0.20.1-0.00.1-0.50.3-0.2-0.2
Pavlov. Cond. magazine entry number0.20.30.40.50.40.5-0.50.6-0.60.50.6
Pavlov. Cond. intertrial magazine entries0.20.20.50.30.50.4-0.50.7-0.60.30.3
Pavlov. Cond. lever-magazine prob. diff.1.41.82.4-1.4-1.0-1.21.3-1.61.4-1.4-1.4
Pavlov. Cond. response bias0.30.40.8-0.7-0.4-0.60.6-0.90.8-0.7-0.7
Conditioned reinforcement - actives0.30.30.40.50.70.5-0.60.4-0.50.50.5
Conditioned reinforcement - inactives0.10.10.20.40.50.4-0.40.3-0.30.40.3
Conditioned locomotion1.21.41.61.21.31.2-1.21.1-1.21.21.2
Intermittent access intake day 1-15 change0.40.40.7-0.6-0.4-0.70.6-0.90.7-0.6-0.8
Intermittent access intake escalation0.30.30.5-0.4-0.1-0.60.4-0.70.5-0.4-0.7
Intermittent access intake escalation 20.30.30.6-0.5-0.1-0.70.4-0.70.5-0.5-0.8
Intermitt. access day 1 inactive lever presses4.14.55.12.12.22.1-2.11.9-2.02.12.3
Intermitt. access day 15 inactive lever presses1.82.02.41.41.51.4-1.51.3-1.41.41.3
Intermitt. access escalation Index0.00.00.10.30.00.3-0.10.1-0.10.30.1
Intermittent access day 1 total infusions5.56.37.12.52.32.6-2.52.5-2.52.52.7
Intermittent access day 15 total infusions2.52.83.21.71.81.7-1.71.5-1.61.71.7
Intermittent access terminal intake (last 3 days)1.82.02.51.41.61.4-1.51.3-1.41.41.4
Intermittent access total infusions3.23.53.61.91.91.9-1.91.8-1.81.91.9
Intermittent access day 1 locomotion0.10.10.20.2-0.10.3-0.10.1-0.10.20.5
Intermittent access day 15 total locomotion0.10.10.1-0.3-0.2-0.40.3-0.30.3-0.3-0.4
Intermittent access total locomotion0.10.10.20.40.30.4-0.30.3-0.30.40.4
Intermittent access standard deviation1.21.31.81.21.31.1-1.21.0-1.11.21.2
Cocaine induced anxiety0.10.10.40.20.60.1-0.40.3-0.30.20.2
Post-drug Anxiety2.02.32.6-1.6-1.3-1.51.4-1.51.5-1.6-1.6
Baseline Anxiety4.34.55.5-2.1-2.4-2.02.2-2.12.2-2.1-2.1
Lifetime Intake2.62.93.01.71.71.7-1.71.7-1.71.71.7
Incentive Sensitization - Responses4.34.35.12.12.22.0-2.11.9-2.02.12.0
Incentive Sensitization - Breakpoint4.24.24.92.12.22.0-2.11.9-2.02.12.0
Progressive ratio test 1 active lever presses1.31.31.61.11.01.2-1.11.1-1.11.11.3
Progressive ratio test 1 breakpoint1.01.11.41.10.91.1-1.01.0-1.01.11.2
Progressive ratio test 1 inactive lever presses1.11.11.51.11.11.1-1.11.0-1.01.11.2
Progressive ratio test 2 active lever presses3.43.64.01.91.91.9-1.91.8-1.91.92.0
Progressive ratio test 2 breakpoint3.64.04.42.02.02.0-2.01.9-2.02.02.1
Progressive ratio test 2 inactive lever presses4.35.05.42.22.32.2-2.32.1-2.22.22.2
Total sessions with >9 infusions0.80.81.40.81.20.9-1.00.7-0.90.80.9
Short access day 1 total inactive lever presses0.10.10.3-0.4-0.2-0.40.3-0.50.4-0.4-0.1
Short access day 10 total inactive lever presses1.51.61.91.41.31.3-1.21.1-1.21.41.3
Short access day 1 total infusions2.02.12.61.41.41.5-1.41.3-1.41.41.6
Short access day 10 total infusions2.72.93.51.81.51.7-1.61.7-1.71.81.9
Short access total infusions1.61.71.91.31.21.4-1.31.3-1.31.31.4
Short access day 1 locomotion0.10.10.1-0.2-0.4-0.20.3-0.30.3-0.2-0.1
Short access day 10 total locomotion0.50.50.80.80.50.9-0.70.7-0.70.80.9
Short access total locomotion0.10.10.30.40.10.5-0.30.3-0.30.40.6
Compulsive drug intake1.21.21.91.11.41.0-1.20.9-1.01.10.9
One hour access (0.3 mA shock)1.72.02.71.51.61.4-1.51.2-1.31.51.3
One hour access (shock baseline)0.40.50.70.80.60.8-0.70.6-0.70.80.8
Number of responses in last shaping day0.10.20.30.40.20.4-0.30.4-0.40.40.5
Context. condit. distance diff. score0.70.81.11.00.81.0-0.90.8-0.81.01.0
Locomotion velocity, session 12.22.32.9-1.5-1.4-1.41.5-1.71.6-1.5-1.5
Locomotion distance, session 12.73.54.2-1.8-1.7-1.81.9-2.02.0-1.8-1.8
Locomotion velocity, session 24.24.95.5-2.3-2.0-2.22.2-2.22.2-2.3-2.3
Locomotion distance, session 21.21.72.5-1.4-1.0-1.21.2-1.61.4-1.4-1.3
Locomotion velocity, session 31.41.62.3-1.2-1.5-1.11.4-1.21.3-1.2-1.2
Locomotion distance, session 30.40.50.70.80.60.8-0.60.5-0.60.80.7
Stereotopy head waving bouts, day 31.41.72.0-1.4-1.1-1.31.2-1.31.3-1.4-1.4
Stereotopy head waving duration, day 30.60.81.1-1.0-0.7-0.80.8-0.70.8-1.0-0.9
Locomotion velocity, session 72.32.52.81.71.51.5-1.61.5-1.51.71.7
Locomotion distance, session 70.30.40.50.70.60.5-0.60.6-0.60.70.7
Stereotopy head waving bouts, day 70.00.00.10.10.10.3-0.10.2-0.20.10.1
Stereotopy head waving duration, day 70.10.10.20.20.30.4-0.30.3-0.30.20.2
Locomotion velocity, session 81.11.41.6-1.2-1.2-1.01.2-1.31.2-1.2-1.0
Locomotion distance, session 80.00.00.1-0.1-0.10.00.2-0.40.3-0.10.0
Degree of sensitization distance0.20.20.4-0.6-0.4-0.60.4-0.30.4-0.6-0.5
Degree of sensitization stereotypy1.41.51.71.21.11.3-1.21.2-1.21.21.2
Condit. Reinf. active minus inactive responses0.30.30.5-0.7-0.3-0.70.5-0.40.5-0.7-0.7
Condit. Reinf. active-inactive response ratio0.10.10.1-0.4-0.0-0.30.1-0.10.1-0.4-0.3
Condit. Reinf. active responses0.20.30.5-0.60.0-0.60.3-0.50.4-0.6-0.7
Condit. Reinf. inactive responses0.20.20.4-0.50.1-0.30.2-0.60.4-0.5-0.6
Incentive salience index mean0.20.20.4-0.60.0-0.60.3-0.40.4-0.6-0.6
Condit. Reinf. lever presses0.10.10.2-0.30.5-0.3-0.1-0.30.1-0.3-0.3
Time in familiar zone, hab. session 11.71.62.01.30.91.4-1.21.3-1.21.31.4
Time in novel zone, hab. session 10.10.10.1-0.2-0.3-0.30.3-0.20.2-0.2-0.3
Total zone transitions, hab. session 10.20.20.4-0.4-0.3-0.40.4-0.70.6-0.4-0.5
Total locomotion distance, hab. session 10.30.40.8-0.7-0.3-0.60.6-0.90.7-0.7-0.7
Locomotion velocity, hab. session 10.71.01.6-1.0-0.5-1.00.9-1.31.1-1.0-1.1
Time in familiar zone, hab. session 20.20.20.30.40.60.5-0.50.5-0.50.40.6
Time in novel zone, hab. session 20.50.50.9-0.6-0.9-0.70.8-0.60.7-0.6-0.8
Total zone transitions, hab. session 21.82.33.1-1.5-1.2-1.51.4-1.81.6-1.5-1.4
Total locomotion distance, hab. session 22.33.04.0-1.7-1.4-1.71.7-2.01.8-1.7-1.7
Locomotion velocity, hab. session 21.82.43.5-1.5-1.2-1.51.5-1.91.7-1.5-1.5
Novel to familiar place preference ratio1.21.31.81.10.91.0-1.11.3-1.21.11.2
Novelty place preference1.81.92.41.31.21.3-1.31.5-1.41.31.4
Time in novel zone, NPP test2.12.22.81.51.31.4-1.41.7-1.61.51.5
Total zone transitions, NPP test1.62.22.8-1.5-1.3-1.51.5-1.71.6-1.5-1.5
Total locomotion distance, NPP test1.41.92.6-1.4-1.0-1.51.3-1.61.5-1.4-1.4
Locomotion velocity, NPP test2.02.93.9-1.7-1.3-1.81.6-2.01.8-1.7-1.7
Pavlov. Cond. lever latency1.41.82.31.30.91.5-1.21.5-1.41.31.5
Pavlov. Cond. magazine entry latency0.00.00.0-0.00.1-0.0-0.0-0.10.0-0.0-0.1
Pavlov. Cond. change in total contacts1.71.82.1-1.3-1.0-1.41.2-1.41.4-1.3-1.5
Pavlov. Cond. index score0.30.40.6-0.6-0.3-0.70.5-0.80.6-0.6-0.7
Pavlov. Cond. latency score0.50.70.9-0.8-0.4-1.00.7-1.00.8-0.8-0.9
Pavlov. Cond. lever contacts2.93.44.2-1.8-1.3-2.11.7-2.01.9-1.8-2.0
Pavlov. Cond. magazine entry number0.30.30.7-0.6-0.8-0.50.7-0.40.5-0.6-0.5
Pavlov. Cond. intertrial magazine entries2.32.73.2-1.7-1.7-1.71.7-1.41.5-1.7-1.8
Pavlov. Cond. lever-magazine prob. diff.0.60.70.9-0.9-0.5-0.90.8-0.90.8-0.9-0.9
Pavlov. Cond. response bias0.40.40.7-0.7-0.2-0.70.5-0.80.7-0.7-0.7
Bone: apparent density0.10.10.3-0.4-0.1-0.30.3-0.60.4-0.4-0.3
Bone surface0.00.00.1-0.10.1-0.10.0-0.30.2-0.1-0.1
Bone volume0.00.10.2-0.30.1-0.20.1-0.50.3-0.3-0.2
Bone: connectivity density0.00.10.10.20.40.3-0.30.1-0.20.20.3
Bone: cortical apparent density2.73.53.91.91.81.9-1.92.0-1.91.91.9
Bone: cortical area0.71.11.81.01.31.1-1.10.7-0.91.01.1
Bone: cortical porosity0.80.81.2-1.1-0.6-1.00.8-0.90.8-1.1-1.0
Bone: cortical porosity1.71.82.3-1.5-1.0-1.51.2-1.31.2-1.5-1.4
Bone: cortical thickness0.50.91.01.01.01.0-0.90.7-0.81.01.0
Bone: cortical thickness0.20.20.3-0.3-0.5-0.30.5-0.60.5-0.3-0.3
Bone: cortical tissue density2.53.23.61.81.71.8-1.81.9-1.81.81.8
Bone: elastic displacement0.10.10.1-0.3-0.1-0.30.2-0.40.3-0.3-0.3
Bone: elastic work0.00.00.00.10.0-0.0-0.0-0.10.10.10.0
Bone: endosteal estimation0.30.71.70.71.30.6-0.90.6-0.70.70.7
Bone: endosteal perimeter0.10.30.6-0.60.0-0.60.3-0.80.5-0.6-0.5
Bone: final force1.42.22.71.61.61.4-1.51.3-1.41.61.6
Bone: final moment0.91.51.91.31.41.1-1.31.0-1.11.31.3
Bone: marrow area0.30.71.60.71.30.6-0.90.6-0.70.70.7
Bone: maximum diameter0.30.51.20.71.10.7-0.80.4-0.60.70.7
Bone: maximum force0.71.22.01.11.41.0-1.20.8-1.01.11.2
Bone: maximum moment0.40.61.30.81.10.6-0.90.5-0.70.80.8
Bone: minimum diameter0.91.73.41.11.91.1-1.51.1-1.31.11.2
Bone: periosteal estimation0.61.22.51.01.61.0-1.20.7-1.01.01.0
Bone: periosteal perimeter0.20.30.90.41.00.5-0.60.1-0.40.40.5
Bone: post-yield work0.00.00.1-0.00.4-0.1-0.1-0.0-0.1-0.0-0.0
Bone: stiffness0.81.22.11.11.41.0-1.20.8-1.01.11.1
Bone: tissue strength0.10.10.1-0.3-0.0-0.30.1-0.30.2-0.3-0.3
Bone: trabecular number0.40.60.8-0.8-0.7-0.70.8-0.90.8-0.8-0.7
Bone: trabecular spacing0.00.00.0-0.1-0.10.10.10.1-0.0-0.1-0.1
Bone: trabecular thickness1.01.21.51.01.21.1-1.11.0-1.11.01.1
Bone: trabecular tissue density0.60.91.00.91.00.9-1.00.9-1.00.91.0
Breakpoint value in progressive ratio session1.61.82.01.41.21.3-1.31.4-1.31.41.4
Distance traveled before self-admin7.68.28.83.02.82.8-2.82.8-2.83.03.0
Distance traveled after self-admin2.83.13.41.81.81.7-1.71.6-1.71.81.8
Delta time in closed arm before/after self-admin0.10.10.1-0.30.1-0.20.1-0.20.2-0.3-0.3
Delta time in open arm before/after self-admin0.20.20.30.40.40.4-0.40.5-0.50.40.4
Diff in mean of infusions in LGA sessions0.00.00.0-0.10.1-0.1-0.0-0.00.0-0.1-0.0
Extinction: sum of active levers before priming0.60.60.70.80.90.7-0.80.7-0.80.80.8
Active lever presses in extinction session 60.30.30.40.50.60.5-0.60.7-0.60.50.6
Delta distance traveled before/after self-admin0.20.20.3-0.5-0.3-0.50.4-0.60.5-0.5-0.5
Delta ambulatory time before/after self-admin0.50.50.6-0.8-0.6-0.70.7-0.80.7-0.8-0.8
Time in closed arm before self-admin5.86.67.02.72.42.6-2.52.5-2.52.72.6
Time in closed arm after self-admin1.41.42.01.11.41.2-1.31.2-1.21.11.1
Time in open arm before self-admin1.41.41.5-1.2-1.1-1.21.2-1.21.2-1.2-1.2
Time in open arm after self-admin0.50.50.6-0.8-0.8-0.80.7-0.60.7-0.8-0.8
Sum of active levers in priming session hrs 5-60.30.30.40.60.50.6-0.60.6-0.60.60.6
Time to tail flick, vehicle, before self-admin1.61.62.2-1.2-1.5-1.31.3-1.11.2-1.2-1.2
Time to tail flick, vehicle, after self-admin0.00.00.10.10.30.1-0.30.3-0.30.10.1
Time to tail flick, test, before self-admin0.00.00.1-0.1-0.2-0.10.2-0.20.2-0.1-0.2
Time to tail flick, test, after self-admin0.40.40.70.50.80.6-0.70.6-0.70.50.5
Delta time to tail flick, vehicle, before/after SA1.21.21.51.01.21.1-1.21.1-1.11.01.0
Delta time to tail flick, test, before/after SA0.00.00.0-0.20.2-0.2-0.0-0.10.0-0.2-0.1
Ambulatory time before self-admin5.25.45.82.42.42.2-2.42.2-2.32.42.4
Ambulatory time after self-admin2.32.53.21.61.81.5-1.61.4-1.51.61.6
Total heroin consumption1.61.92.21.41.11.4-1.31.4-1.31.41.5
Area under the delay curve0.60.60.7-0.8-0.8-0.70.8-0.80.8-0.8-0.8
Delay disc. indifference point, 0s delay1.71.82.1-1.3-1.4-1.21.4-1.51.4-1.3-1.3
Delay disc. indifference point, 16s delay0.00.00.00.0-0.0-0.00.0-0.10.00.00.0
Delay disc. indifference point, 2s delay0.30.30.4-0.5-0.7-0.50.6-0.50.5-0.5-0.5
Delay disc. indifference point, 24s delay0.00.00.0-0.10.0-0.20.0-0.10.1-0.1-0.1
Delay disc. indifference point, 4s delay0.60.60.7-0.8-0.8-0.60.8-0.80.8-0.8-0.8
Delay disc. indifference point, 8s delay0.50.50.7-0.7-0.8-0.60.8-0.70.7-0.7-0.7
Delay discount exponential model param0.40.50.50.70.70.6-0.70.7-0.70.70.7
Delay discount hyperbolic model param0.50.50.60.70.80.6-0.80.7-0.70.70.7
Fecal boli incidents, locomotor time 14.95.46.02.42.32.2-2.32.2-2.32.42.2
Change in fecal boli incidents, locomotor task5.45.16.0-2.3-2.4-2.22.3-2.12.2-2.3-2.1
Time >=10cm from walls, locomotor time 12.92.93.51.71.61.7-1.71.9-1.81.71.5
Bouts of movement, locomotor time 10.10.10.4-0.2-0.6-0.10.3-0.10.2-0.2-0.3
Total resting periods, locomotor time 10.00.00.2-0.0-0.40.10.20.10.0-0.0-0.1
Rest time, locomotor task time 10.80.81.50.80.61.0-0.81.2-1.00.80.8
Distance moved, locomotor task time 10.70.81.1-0.9-0.8-0.80.9-1.11.0-0.9-0.7
Vertical activity count, locomotor time 11.61.72.5-1.2-1.0-1.41.2-1.61.4-1.2-1.2
Time >=10cm from walls, locomotor time 22.42.53.11.81.21.5-1.41.7-1.61.81.7
Bouts of movement, locomotor time 20.00.00.20.0-0.4-0.10.20.10.00.0-0.2
Total resting periods, locomotor time 20.10.10.4-0.1-0.6-0.20.30.10.1-0.1-0.4
Rest time, locomotor task time 20.81.01.80.90.71.1-0.91.3-1.10.90.6
Distance moved, locomotor task time 20.00.00.1-0.30.0-0.20.1-0.30.2-0.30.1
Vertical activity count, locomotor time 20.40.40.9-0.6-0.3-0.80.6-1.00.8-0.6-0.5
Weight adjusted by age1.41.62.01.41.01.1-1.21.3-1.21.41.4
Seeking ratio, delayed vs. immediate footshock0.20.20.4-0.3-0.6-0.30.5-0.50.5-0.3-0.3
Locomotion in novel chamber0.10.10.40.3-0.30.6-0.10.2-0.20.30.3
Locomotion in novel chamber post-restriction0.00.00.0-0.00.20.1-0.1-0.0-0.0-0.0-0.0
Progressive ratio0.30.40.50.60.60.6-0.60.6-0.60.60.7
Food seeking constrained by brief footshock2.22.63.01.51.71.6-1.71.7-1.71.51.6
Seeking ratio, punishment vs. effort0.00.00.00.10.20.1-0.20.2-0.20.10.0
Run reversals in cocaine runway, females0.60.60.70.80.50.9-0.60.7-0.70.80.9
Run reversals in cocaine runway, males3.13.03.51.81.31.8-1.61.9-1.71.81.8
Latency to leave start box in cocaine runway0.40.50.6-0.7-0.6-0.80.6-0.60.6-0.7-0.7
Latency to leave start box in cocaine runway, F0.10.10.2-0.2-0.4-0.30.3-0.30.3-0.2-0.2
Latency to leave start box in cocaine runway, M1.71.62.1-1.4-1.0-1.41.1-1.11.1-1.4-1.4
Cd content in liver0.40.40.60.80.40.8-0.60.6-0.60.80.8
Co content in liver0.20.20.3-0.5-0.2-0.40.4-0.60.5-0.5-0.5
Cu content in liver0.10.10.20.20.00.4-0.20.4-0.30.20.2
Fe content in liver0.70.81.0-0.9-0.8-0.80.9-1.00.9-0.9-0.9
K content in liver0.10.10.2-0.3-0.4-0.30.3-0.20.3-0.3-0.3
Mg content in liver0.10.10.20.40.10.4-0.30.4-0.30.40.4
Mn content in liver0.00.10.10.20.40.1-0.30.1-0.20.20.2
Na content in liver0.00.00.1-0.20.1-0.10.1-0.30.2-0.2-0.2
Rb content in liver1.92.32.61.51.41.5-1.51.6-1.61.51.5
Se content in liver0.10.10.4-0.4-0.6-0.30.4-0.10.3-0.4-0.4
Sr content in liver2.72.43.3-1.6-1.2-1.61.5-1.81.6-1.6-1.6
Zn content in liver2.73.03.61.81.51.9-1.71.7-1.71.81.8