Ptpra

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose intron excision ratio chr3:117705569:117714664 0.02 0.02 8.5e-03 0.01 0 0 0 2.7e-02 8.5e-02 1.9e-01 1.0e-01
2 BLA gene expression ENSRNOG00000021223 0.11 0.08 2.7e-04 0.02 0.05 0.05 0.04 2.1e-02 1.1e-03 1.5e-03 3.8e-03
3 Brain gene expression ENSRNOG00000021223 0.11 0.08 1.6e-07 0.07 0.07 0.06 0.07 6.7e-07 2.9e-07 6.2e-06 3.0e-07
4 IL gene expression ENSRNOG00000021223 0.24 0.18 6.3e-03 0.03 0.1 0.04 0.08 7.5e-02 2.2e-03 3.6e-02 4.7e-03
5 Liver gene expression ENSRNOG00000021223 0.02 0.02 1.4e-03 0.02 0.01 0.01 0.02 1.5e-03 1.6e-02 8.8e-03 3.6e-03
6 NAcc gene expression ENSRNOG00000021223 0.07 0.05 6.9e-06 0.06 0.07 0.07 0.06 1.9e-05 8.5e-06 7.1e-06 1.4e-05
7 PL gene expression ENSRNOG00000021223 0.06 0.05 5.4e-04 0.03 0.04 0.04 0.04 1.3e-03 4.5e-04 9.0e-04 8.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail1.13.75.12.3-1.8-1.9-1.7-1.8-2.1-1.9
BMI without tail3.77.89.83.1-2.6-2.8-2.5-2.7-3.0-2.7
Body weight5.824.427.15.2-4.6-5.1-4.2-5.1-5.2-5.1
Epididymis fat weight1.33.13.71.9-1.6-1.9-1.4-1.8-1.9-1.9
Glucose0.30.40.90.7-0.2-0.9-0.1-0.4-0.6-0.9
Heart weight2.94.16.62.2-1.1-2.6-0.7-2.0-2.2-2.5
Left kidney weight0.92.53.81.8-0.9-1.9-0.7-1.6-1.7-1.9
Right kidney weight0.82.23.71.6-0.8-1.9-0.5-1.4-1.6-1.9
Tail length5.015.016.84.0-3.9-3.8-3.7-4.0-4.1-3.7
Length with tail4.516.418.74.1-3.6-4.3-3.2-4.3-4.3-4.3
Length without tail1.22.63.41.6-1.3-1.8-1.2-1.8-1.7-1.8
Liver weight, left0.20.41.2-0.30.9-0.11.10.50.3-0.1
Liver weight, right0.10.10.30.4-0.50.0-0.6-0.0-0.30.1
Parametrial fat weight0.10.10.40.10.30.40.30.60.30.4
Retroperitoneal fat weight0.00.10.20.40.20.20.20.5-0.00.2
Intraocular pressure0.00.10.2-0.2-0.4-0.0-0.4-0.2-0.0-0.0
Extensor digitorum longus weight0.10.20.30.5-0.4-0.5-0.4-0.6-0.5-0.5
Soleus weight0.00.10.20.00.2-0.40.3-0.2-0.1-0.4
Tibialis anterior weight0.82.63.01.7-1.5-1.7-1.4-1.7-1.7-1.7
Tibia length4.412.513.23.5-3.6-3.5-3.4-3.6-3.6-3.5
Number of licking bursts0.30.30.5-0.7-0.20.7-0.40.50.50.7
Food consumed during 24 hour testing period0.91.11.4-1.21.10.91.11.21.10.9
Times rat made contact with spout0.10.10.3-0.40.4-0.10.50.20.3-0.1
Mean time between licks in bursts0.00.00.10.3-0.10.1-0.10.1-0.10.1
Mean num. licks in bursts0.30.30.70.40.4-0.80.7-0.4-0.3-0.8
Std. dev. time between licks in bursts0.50.61.21.1-0.4-0.8-0.3-0.6-0.9-0.8
Water consumed over 24 hours0.10.10.5-0.70.10.40.00.20.50.4
Indifference point 0 sec0.20.30.6-0.00.4-0.80.7-0.4-0.1-0.8
Indifference point AUC0.50.60.80.9-0.8-0.8-0.8-0.7-0.8-0.8
Indifference point function ln k0.10.10.20.40.1-0.50.3-0.2-0.3-0.5
Indifference point function log k0.10.10.20.40.1-0.50.3-0.2-0.3-0.5
Delay discounting total patch changes 0 sec0.20.30.70.00.4-0.80.7-0.4-0.2-0.8
Delay discounting total patch changes 12 sec0.30.40.70.8-0.5-0.8-0.4-0.5-0.7-0.8
Delay discounting total patch changes 18 sec0.81.01.8-1.11.30.61.30.91.00.7
Delay discounting total patch changes 24 sec1.72.13.5-1.51.81.01.91.41.51.0
Delay discounting total patch changes 6 sec0.40.71.60.60.0-1.30.3-0.8-0.7-1.2
Delay discounting time to switch 0 sec1.82.74.8-1.60.92.20.51.71.72.2
Delay discounting water rate 0 sec3.55.610.02.3-1.3-3.1-0.8-2.4-2.4-3.2
Delay discounting water rate 12 sec0.10.20.3-0.10.3-0.50.5-0.4-0.1-0.6
Delay discounting water rate 18 sec0.30.40.70.6-0.5-0.8-0.4-0.6-0.7-0.8
Delay discounting water rate 24 sec0.50.71.00.7-1.0-0.7-1.0-0.9-0.8-0.8
Delay discounting water rate 6 sec1.82.63.31.4-1.5-1.8-1.4-1.8-1.6-1.8
Locomotor activity0.20.20.30.5-0.6-0.4-0.6-0.5-0.4-0.4
Locomotor testing distance0.10.20.3-0.60.40.30.40.30.40.2
Locomotor testing rearing0.20.30.70.3-0.1-0.80.1-0.6-0.4-0.8
Light reinforcement 11.01.82.71.1-1.5-1.2-1.4-1.7-1.4-1.2
Light reinforcement 20.70.91.60.8-1.0-0.9-0.9-1.3-1.0-0.9
Reaction time number correct0.20.30.90.3-0.2-0.90.0-0.6-0.5-0.9
Reaction time mean minus median0.81.01.4-1.21.01.00.90.91.00.9
Reaction time mean minus median AUC0.50.71.1-1.00.90.70.90.60.80.7
Reaction time num false alarms1.82.53.51.8-1.0-1.9-0.7-1.6-1.7-1.8
Reaction time num false alarms AUC2.02.73.71.9-1.3-1.8-1.1-1.7-1.8-1.8
Reaction time trials correct on left0.20.30.90.3-0.2-0.90.0-0.6-0.5-0.9
Reaction time trials on left0.30.41.00.4-0.2-1.0-0.0-0.7-0.5-1.0
Reaction time mean0.00.00.1-0.2-0.20.2-0.20.10.10.2
Reaction time mean AUC0.00.00.1-0.3-0.00.3-0.10.10.20.3
Median of all reaction times0.00.10.20.1-0.4-0.1-0.4-0.2-0.2-0.1
Reaction time omissions0.40.50.80.5-0.3-0.9-0.2-0.9-0.8-0.9
Reaction time false alarm rate1.01.42.21.5-1.0-1.2-0.9-1.1-1.4-1.1
Reaction time premature initiation rate0.20.20.4-0.60.10.7-0.10.30.50.6
Reaction time premature initiations0.10.10.2-0.50.10.30.10.10.40.2
Std. dev. reaction times0.10.20.60.2-0.7-0.1-0.7-0.5-0.3-0.2
Reaction time trials completed0.30.41.00.4-0.2-1.0-0.0-0.7-0.5-1.0
Reaction time trials AUC0.30.51.10.4-0.3-1.0-0.1-0.7-0.6-1.0
Social response proportion1.51.62.91.0-0.6-1.7-0.3-1.4-1.3-1.7
Social responses4.76.17.32.4-2.2-2.6-2.0-2.7-2.6-2.7
Social time0.50.60.80.7-0.8-0.8-0.7-0.9-0.9-0.8
Conditioned locomotion3.74.56.62.2-1.5-2.6-1.1-2.2-2.2-2.5
Cocaine response after cond. corrected0.20.20.6-0.20.70.20.70.40.30.2
Cocaine response after cond. not corrected0.20.20.4-0.40.60.40.70.40.40.4
Cocaine response before conditioning0.20.20.5-0.70.10.60.00.20.50.5
Saline control response6.79.010.73.2-2.6-3.3-2.3-3.0-3.2-3.3
Condit. Reinf. active minus inactive responses2.02.53.91.3-1.1-2.0-0.9-1.8-1.6-2.0
Condit. Reinf. active-inactive response ratio2.02.13.11.2-1.2-1.7-1.0-1.6-1.4-1.8
Condit. Reinf. active responses3.34.56.91.8-1.6-2.6-1.3-2.4-2.2-2.6
Condit. Reinf. inactive responses0.60.81.40.7-0.4-1.2-0.2-1.0-0.9-1.2
Condit. Reinf. lever presses1.42.02.31.2-1.5-1.4-1.4-1.5-1.4-1.4
Condit. Reinf. lever reinforcers received2.53.55.51.6-1.3-2.3-1.0-2.1-1.9-2.4
Pavlov. Cond. lever latency4.25.76.5-2.42.42.32.32.42.52.3
Pavlov. Cond. magazine entry latency0.10.10.20.30.0-0.50.2-0.2-0.3-0.5
Pavlov. Cond. change in total contacts4.05.66.22.3-2.4-2.2-2.3-2.5-2.5-2.3
Pavlov. Cond. index score3.44.45.22.2-2.0-2.1-1.9-2.1-2.3-2.1
Pavlov. Cond. latency score2.53.23.91.9-1.7-1.8-1.5-1.8-2.0-1.9
Pavlov. Cond. lever contacts3.95.46.22.3-2.3-2.3-2.1-2.4-2.5-2.4
Pavlov. Cond. magazine entry number0.60.70.8-0.80.80.90.70.90.90.9
Pavlov. Cond. intertrial magazine entries1.01.31.5-0.91.21.11.21.21.11.1
Pavlov. Cond. lever-magazine prob. diff.3.03.94.62.1-1.8-2.0-1.7-2.0-2.1-2.0
Pavlov. Cond. response bias4.15.66.42.3-2.2-2.5-2.0-2.5-2.5-2.5
Conditioned reinforcement - actives0.00.00.0-0.1-0.0-0.1-0.0-0.1-0.0-0.1
Conditioned reinforcement - inactives0.40.41.10.30.2-1.00.5-0.6-0.5-1.0
Conditioned locomotion0.10.10.2-0.30.30.20.30.40.30.2
Intermittent access intake day 1-15 change0.40.40.70.7-0.3-0.8-0.2-0.5-0.6-0.8
Intermittent access intake escalation0.10.10.20.2-0.1-0.4-0.0-0.2-0.2-0.4
Intermittent access intake escalation 20.20.20.3-0.40.50.40.60.60.50.4
Intermitt. access day 1 inactive lever presses0.40.41.0-0.80.90.21.00.30.60.1
Intermitt. access day 15 inactive lever presses0.20.20.9-0.20.7-0.30.90.30.2-0.2
Intermitt. access escalation Index0.00.00.10.2-0.20.2-0.30.2-0.00.2
Intermittent access day 1 total infusions0.10.10.2-0.00.10.4-0.00.50.20.5
Intermittent access day 15 total infusions0.00.00.10.10.2-0.20.20.1-0.1-0.2
Intermittent access terminal intake (last 3 days)0.10.10.30.10.4-0.20.50.20.0-0.1
Intermittent access total infusions0.10.10.20.00.40.00.50.40.10.1
Intermittent access day 1 locomotion0.10.10.2-0.50.40.30.40.40.40.3
Intermittent access day 15 total locomotion0.40.41.4-0.31.0-0.21.20.30.4-0.1
Intermittent access total locomotion0.20.20.5-0.30.60.10.70.50.40.2
Intermittent access standard deviation0.10.10.20.1-0.4-0.2-0.4-0.2-0.2-0.2
Cocaine induced anxiety5.76.57.6-2.72.82.22.72.62.72.2
Post-drug Anxiety1.82.02.6-1.61.51.21.41.31.51.2
Baseline Anxiety0.70.70.90.8-0.9-0.7-0.9-1.0-0.9-0.7
Lifetime Intake0.10.10.30.5-0.1-0.4-0.0-0.0-0.4-0.3
Incentive Sensitization - Responses0.20.10.40.7-0.2-0.5-0.1-0.1-0.4-0.4
Incentive Sensitization - Breakpoint0.10.10.20.50.0-0.30.10.1-0.2-0.2
Progressive ratio test 1 active lever presses2.52.63.71.9-1.5-1.6-1.4-1.4-1.7-1.5
Progressive ratio test 1 breakpoint3.23.34.62.2-1.7-1.8-1.5-1.6-2.0-1.8
Progressive ratio test 1 inactive lever presses0.20.20.50.3-0.0-0.70.2-0.5-0.4-0.7
Progressive ratio test 2 active lever presses0.20.20.40.60.1-0.60.2-0.2-0.4-0.5
Progressive ratio test 2 breakpoint0.10.20.40.6-0.0-0.50.1-0.1-0.4-0.4
Progressive ratio test 2 inactive lever presses0.20.20.50.20.4-0.70.7-0.3-0.2-0.7
Total sessions with >9 infusions0.50.50.80.9-0.8-0.6-0.8-0.5-0.8-0.5
Short access day 1 total inactive lever presses0.60.71.0-0.90.61.00.40.80.91.0
Short access day 10 total inactive lever presses4.44.87.5-2.22.61.62.72.22.21.6
Short access day 1 total infusions0.00.00.10.3-0.1-0.1-0.10.1-0.2-0.0
Short access day 10 total infusions0.00.00.10.3-0.20.1-0.30.2-0.20.1
Short access total infusions0.30.30.60.8-0.5-0.5-0.5-0.3-0.7-0.5
Short access day 1 locomotion1.21.32.6-0.91.50.71.61.11.00.7
Short access day 10 total locomotion0.00.00.0-0.1-0.2-0.1-0.2-0.1-0.0-0.1
Short access total locomotion0.00.00.1-0.10.2-0.20.30.00.0-0.2
Compulsive drug intake3.83.84.9-2.21.52.21.31.92.12.2
One hour access (0.3 mA shock)0.10.10.4-0.30.5-0.00.60.40.20.0
One hour access (shock baseline)0.30.30.70.6-0.2-0.8-0.0-0.4-0.6-0.8
Number of responses in last shaping day0.20.20.3-0.60.40.40.40.10.50.4
Context. condit. distance diff. score0.20.20.50.30.5-0.50.7-0.1-0.3-0.4
Locomotion velocity, session 10.30.30.50.6-0.3-0.7-0.2-0.7-0.6-0.7
Locomotion distance, session 10.40.51.00.60.5-1.00.8-0.6-0.5-0.9
Locomotion velocity, session 20.10.10.3-0.10.50.20.50.20.20.2
Locomotion distance, session 21.11.62.91.3-0.3-1.70.0-1.4-1.4-1.6
Locomotion velocity, session 31.41.62.31.5-1.2-1.2-1.1-1.3-1.4-1.2
Locomotion distance, session 36.67.29.53.1-2.4-2.7-2.2-2.7-2.9-2.7
Stereotopy head waving bouts, day 31.41.73.0-1.41.60.81.71.01.30.8
Stereotopy head waving duration, day 30.81.01.6-1.21.10.81.10.81.10.7
Locomotion velocity, session 70.80.91.21.0-0.7-1.1-0.5-1.1-1.0-1.1
Locomotion distance, session 70.60.81.41.2-0.1-1.10.1-1.0-1.1-1.0
Stereotopy head waving bouts, day 70.50.60.80.5-0.9-0.7-0.9-0.8-0.7-0.7
Stereotopy head waving duration, day 70.20.20.50.1-0.7-0.3-0.7-0.4-0.3-0.3
Locomotion velocity, session 80.40.51.10.70.3-1.00.5-0.6-0.7-1.0
Locomotion distance, session 82.02.95.41.9-0.1-2.30.4-1.7-1.9-2.2
Degree of sensitization distance2.32.33.1-1.51.81.31.81.41.51.3
Degree of sensitization stereotypy2.62.94.21.5-2.0-1.4-2.1-1.6-1.6-1.5
Condit. Reinf. active minus inactive responses0.91.01.21.1-1.1-0.8-1.1-1.0-1.0-0.8
Condit. Reinf. active-inactive response ratio0.70.70.90.9-0.8-0.9-0.7-0.9-0.9-0.9
Condit. Reinf. active responses0.70.81.21.1-1.0-0.7-1.0-0.9-1.0-0.7
Condit. Reinf. inactive responses0.00.00.00.10.0-0.00.0-0.1-0.1-0.0
Incentive salience index mean0.60.71.31.1-0.8-0.6-0.8-0.8-0.9-0.6
Condit. Reinf. lever presses0.20.20.60.8-0.4-0.2-0.4-0.3-0.5-0.2
Time in familiar zone, hab. session 11.31.31.4-1.01.21.11.11.11.11.1
Time in novel zone, hab. session 10.40.40.60.6-0.4-0.8-0.3-0.7-0.7-0.8
Total zone transitions, hab. session 10.20.30.50.70.2-0.60.4-0.5-0.5-0.5
Total locomotion distance, hab. session 10.20.20.70.20.6-0.40.8-0.4-0.2-0.4
Locomotion velocity, hab. session 10.10.20.40.30.4-0.50.6-0.4-0.3-0.5
Time in familiar zone, hab. session 21.71.82.2-1.31.41.31.31.51.41.3
Time in novel zone, hab. session 21.71.72.11.2-1.4-1.3-1.3-1.5-1.3-1.3
Total zone transitions, hab. session 22.43.14.32.1-1.5-1.8-1.3-1.8-2.0-1.8
Total locomotion distance, hab. session 20.60.91.61.0-0.0-1.30.2-1.0-1.0-1.2
Locomotion velocity, hab. session 20.40.50.90.60.3-1.00.6-0.6-0.6-0.9
Novel to familiar place preference ratio0.30.30.6-0.50.70.20.80.60.50.3
Novelty place preference0.50.50.8-0.70.90.40.90.80.70.5
Time in novel zone, NPP test0.30.30.5-0.50.70.30.70.70.50.3
Total zone transitions, NPP test0.10.20.40.7-0.4-0.3-0.4-0.6-0.6-0.3
Total locomotion distance, NPP test0.30.40.60.50.4-0.80.6-0.6-0.5-0.7
Locomotion velocity, NPP test0.10.20.70.10.6-0.40.8-0.3-0.1-0.4
Pavlov. Cond. lever latency0.30.40.9-0.1-0.9-0.3-1.0-0.8-0.3-0.4
Pavlov. Cond. magazine entry latency0.00.10.10.3-0.1-0.3-0.0-0.2-0.3-0.3
Pavlov. Cond. change in total contacts0.10.10.20.50.0-0.20.1-0.1-0.3-0.2
Pavlov. Cond. index score0.00.00.10.30.2-0.00.20.2-0.10.0
Pavlov. Cond. latency score0.10.10.30.10.50.20.60.40.10.2
Pavlov. Cond. lever contacts0.10.10.50.70.1-0.30.20.0-0.4-0.2
Pavlov. Cond. magazine entry number0.70.81.3-0.91.10.61.20.80.90.7
Pavlov. Cond. intertrial magazine entries0.10.10.30.1-0.0-0.50.1-0.4-0.2-0.5
Pavlov. Cond. lever-magazine prob. diff.0.00.00.10.30.20.00.20.2-0.10.1
Pavlov. Cond. response bias0.40.50.90.9-0.6-0.7-0.6-0.6-0.8-0.6
Bone: apparent density0.40.61.30.8-0.0-1.10.2-0.7-0.8-1.1
Bone surface0.61.11.91.2-0.5-1.4-0.2-1.0-1.1-1.3
Bone volume0.61.01.81.1-0.4-1.3-0.2-1.0-1.1-1.3
Bone: connectivity density0.20.30.60.40.1-0.80.4-0.4-0.4-0.7
Bone: cortical apparent density0.91.22.50.9-1.5-0.6-1.6-1.1-1.0-0.6
Bone: cortical area3.35.06.92.6-1.9-2.4-1.8-2.1-2.4-2.3
Bone: cortical porosity0.50.51.60.7-1.10.1-1.3-0.2-0.50.1
Bone: cortical porosity0.91.02.61.1-1.4-0.3-1.6-0.6-0.9-0.3
Bone: cortical thickness1.62.63.82.0-1.5-1.5-1.4-1.4-1.8-1.5
Bone: cortical thickness0.30.40.50.6-0.7-0.5-0.7-0.4-0.6-0.5
Bone: cortical tissue density0.81.02.20.8-1.4-0.5-1.5-1.0-0.9-0.5
Bone: elastic displacement0.10.20.6-0.1-0.60.3-0.8-0.10.00.3
Bone: elastic work0.10.10.50.2-0.60.1-0.7-0.2-0.20.1
Bone: endosteal estimation0.51.01.41.2-0.7-1.2-0.6-0.9-1.1-1.1
Bone: endosteal perimeter2.04.15.62.2-1.6-2.4-1.4-1.9-2.2-2.3
Bone: final force3.55.87.42.7-2.2-2.5-2.0-2.3-2.6-2.5
Bone: final moment2.74.56.12.5-1.9-2.2-1.7-2.0-2.3-2.2
Bone: marrow area0.40.91.31.1-0.6-1.1-0.5-0.8-1.0-1.1
Bone: maximum diameter4.17.59.63.0-2.3-3.1-2.0-2.6-2.9-3.1
Bone: maximum force0.61.11.71.3-0.9-1.2-0.8-0.9-1.2-1.1
Bone: maximum moment0.30.50.90.9-0.5-0.8-0.4-0.4-0.8-0.8
Bone: minimum diameter1.62.94.52.1-1.3-1.9-1.1-1.4-1.9-1.9
Bone: periosteal estimation2.34.66.22.5-1.8-2.3-1.6-2.0-2.3-2.3
Bone: periosteal perimeter3.15.16.92.6-1.7-2.6-1.4-2.1-2.5-2.6
Bone: post-yield work0.60.91.3-1.00.80.90.81.11.00.9
Bone: stiffness1.82.84.12.0-1.4-1.8-1.2-1.5-1.8-1.8
Bone: tissue strength0.20.20.20.5-0.3-0.4-0.2-0.5-0.5-0.4
Bone: trabecular number0.60.91.50.9-0.6-1.2-0.4-1.1-0.9-1.2
Bone: trabecular spacing0.10.10.3-0.30.00.5-0.10.40.30.5
Bone: trabecular thickness0.30.40.70.8-0.3-0.8-0.1-0.5-0.7-0.8
Bone: trabecular tissue density1.41.92.71.6-1.0-1.6-0.9-1.3-1.5-1.6
Breakpoint value in progressive ratio session3.13.54.02.0-1.9-1.7-1.9-2.0-1.9-1.7
Distance traveled before self-admin4.34.67.12.4-1.5-2.7-1.2-1.8-2.4-2.6
Distance traveled after self-admin2.72.94.21.7-1.3-2.1-1.0-1.8-1.9-2.0
Delta time in closed arm before/after self-admin0.20.20.3-0.40.40.60.30.40.50.6
Delta time in open arm before/after self-admin0.80.81.90.60.2-1.40.6-0.6-0.8-1.3
Diff in mean of infusions in LGA sessions0.00.00.10.0-0.10.3-0.20.10.10.3
Extinction: sum of active levers before priming0.70.70.80.7-0.9-0.8-0.9-0.8-0.8-0.8
Active lever presses in extinction session 60.20.10.3-0.30.50.20.50.40.30.3
Delta distance traveled before/after self-admin0.30.30.60.4-0.6-0.4-0.6-0.8-0.5-0.4
Delta ambulatory time before/after self-admin0.40.40.9-0.70.30.90.20.30.71.0
Time in closed arm before self-admin0.20.20.3-0.30.40.50.40.50.50.5
Time in closed arm after self-admin0.50.51.1-0.50.41.00.20.70.71.0
Time in open arm before self-admin0.20.20.4-0.40.10.6-0.00.50.40.6
Time in open arm after self-admin0.20.20.5-0.00.4-0.70.6-0.0-0.3-0.7
Sum of active levers in priming session hrs 5-61.01.01.60.9-0.7-1.2-0.6-1.1-1.0-1.3
Time to tail flick, vehicle, before self-admin2.12.12.9-1.61.71.21.71.01.51.3
Time to tail flick, vehicle, after self-admin0.00.00.00.1-0.10.1-0.20.1-0.00.1
Time to tail flick, test, before self-admin1.31.31.91.0-1.3-0.8-1.4-1.2-1.1-0.9
Time to tail flick, test, after self-admin2.42.53.2-1.61.81.31.81.71.61.3
Delta time to tail flick, vehicle, before/after SA3.53.44.22.0-1.8-1.8-1.7-1.6-2.0-1.8
Delta time to tail flick, test, before/after SA3.53.14.7-1.92.11.22.21.71.71.3
Ambulatory time before self-admin3.94.15.12.2-1.7-2.3-1.5-2.0-2.2-2.2
Ambulatory time after self-admin3.53.84.92.0-1.6-2.2-1.4-2.0-2.1-2.1
Total heroin consumption3.54.25.12.0-1.9-2.1-1.8-2.3-2.1-2.1
Area under the delay curve0.20.20.6-0.40.10.8-0.10.40.40.7
Delay disc. indifference point, 0s delay2.52.73.9-1.61.22.01.01.81.72.0
Delay disc. indifference point, 16s delay0.60.61.1-0.60.51.00.30.70.81.0
Delay disc. indifference point, 2s delay0.00.00.0-0.0-0.00.2-0.00.20.20.2
Delay disc. indifference point, 24s delay2.22.23.1-1.41.21.81.01.51.51.7
Delay disc. indifference point, 4s delay0.10.20.50.3-0.60.1-0.7-0.2-0.20.1
Delay disc. indifference point, 8s delay0.30.30.8-0.4-0.10.9-0.30.40.40.8
Delay discount exponential model param0.20.20.50.3-0.0-0.70.1-0.4-0.4-0.7
Delay discount hyperbolic model param0.10.20.40.2-0.0-0.60.1-0.4-0.4-0.6
Fecal boli incidents, locomotor time 10.10.10.20.3-0.4-0.2-0.4-0.3-0.3-0.2
Change in fecal boli incidents, locomotor task0.10.10.1-0.40.40.20.40.20.30.3
Time >=10cm from walls, locomotor time 10.10.10.20.2-0.4-0.2-0.5-0.2-0.2-0.2
Bouts of movement, locomotor time 11.92.23.3-1.41.01.80.71.71.51.8
Total resting periods, locomotor time 11.51.72.7-1.30.81.60.51.41.31.7
Rest time, locomotor task time 10.20.20.4-0.50.20.70.00.40.50.6
Distance moved, locomotor task time 10.00.00.10.10.1-0.30.2-0.2-0.2-0.3
Vertical activity count, locomotor time 10.20.20.40.60.1-0.60.3-0.3-0.4-0.6
Time >=10cm from walls, locomotor time 20.00.00.00.1-0.00.1-0.10.2-0.00.1
Bouts of movement, locomotor time 20.60.61.2-0.60.11.1-0.11.10.81.1
Total resting periods, locomotor time 20.60.71.3-0.7-0.11.1-0.31.00.81.1
Rest time, locomotor task time 20.50.61.2-1.1-0.21.0-0.40.50.80.8
Distance moved, locomotor task time 20.30.31.20.30.9-0.41.10.2-0.1-0.3
Vertical activity count, locomotor time 20.40.50.90.70.6-0.90.9-0.1-0.4-0.8
Weight adjusted by age3.53.95.21.8-1.5-2.3-1.3-2.3-2.1-2.3
Seeking ratio, delayed vs. immediate footshock0.20.20.3-0.50.40.50.30.40.50.5
Locomotion in novel chamber0.10.10.2-0.40.20.40.10.30.40.4
Locomotion in novel chamber post-restriction1.01.21.61.0-1.0-1.1-0.9-1.3-1.1-1.2
Progressive ratio2.52.94.0-1.91.22.01.01.81.82.0
Food seeking constrained by brief footshock0.40.50.90.70.4-1.00.6-0.5-0.5-1.0
Seeking ratio, punishment vs. effort2.63.25.12.1-0.9-2.3-0.6-1.8-1.9-2.2
Run reversals in cocaine runway, females0.10.10.4-0.20.5-0.20.60.10.2-0.3
Run reversals in cocaine runway, males0.90.91.40.9-0.5-1.2-0.3-1.1-1.0-1.2
Latency to leave start box in cocaine runway0.50.50.9-0.40.60.90.51.00.70.9
Latency to leave start box in cocaine runway, F1.21.31.9-0.91.01.30.91.41.11.3
Latency to leave start box in cocaine runway, M0.10.10.10.4-0.1-0.3-0.0-0.1-0.3-0.3
Cd content in liver0.10.10.1-0.10.30.40.30.20.20.4
Co content in liver0.70.81.10.9-0.7-1.0-0.6-1.0-1.0-1.0
Cu content in liver1.92.33.01.5-1.2-1.7-1.0-1.7-1.6-1.7
Fe content in liver0.00.10.20.10.3-0.20.40.1-0.1-0.2
K content in liver0.30.30.50.7-0.4-0.6-0.3-0.4-0.6-0.5
Mg content in liver1.51.62.21.5-0.9-1.5-0.8-1.2-1.4-1.4
Mn content in liver2.02.32.91.7-1.3-1.5-1.2-1.6-1.6-1.5
Na content in liver0.10.10.20.20.30.20.30.40.10.2
Rb content in liver3.24.07.12.0-1.0-2.7-0.5-2.2-2.1-2.6
Se content in liver0.70.91.20.9-0.6-1.1-0.5-1.0-1.0-1.1
Sr content in liver0.50.50.60.7-0.7-0.6-0.7-0.6-0.7-0.6
Zn content in liver0.20.30.50.7-0.2-0.6-0.1-0.4-0.6-0.6