Hub : Genes

Vps16

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain alternative polyA ENSRNOT00000028821 0.04 0.03 8.8e-04 0.01 0.02 0.02 0.02 5.4e-02 2.6e-03 4.8e-03 1.1e-02
2 Brain alternative polyA ENSRNOT00000114809 0.04 0.03 7.1e-04 0.02 0.03 0.02 0.02 7.5e-03 1.7e-03 5.2e-03 6.1e-03
3 Brain alternative polyA ENSRNOT00000028821 0.03 0.03 1.7e-03 0.01 0.02 0.02 0.01 8.4e-02 5.3e-03 1.1e-02 2.5e-02
4 Brain alternative polyA ENSRNOT00000114809 0.03 0.03 1.2e-03 0.02 0.02 0.02 0.02 4.6e-03 2.7e-03 8.8e-03 1.1e-02
5 Brain isoform ratio ENSRNOT00000028821 0.02 0.02 4.4e-03 0.02 0.02 0.02 0.02 5.3e-03 4.6e-03 3.1e-03 7.0e-03
6 Brain isoform ratio ENSRNOT00000114809 0.02 0.02 4.3e-03 0.01 0.02 0.02 0.01 1.6e-02 3.8e-03 9.0e-03 1.3e-02
7 Brain mRNA stability ENSRNOG00000021222 0.03 0.02 2.0e-03 0.01 0.02 0.01 0.01 3.0e-02 9.4e-03 2.2e-02 4.1e-02
8 Liver gene expression ENSRNOG00000021222 0.15 0.09 0.0e+00 0.13 0.13 0.13 0.13 3.0e-14 5.6e-14 2.5e-14 4.1e-14

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail1.13.55.11.9-1.91.9-1.92.2-1.91.9-0.9
BMI without tail3.67.510.12.8-2.82.8-2.83.2-2.82.8-1.6
Body weight5.824.427.54.9-5.04.9-5.05.2-5.15.0-4.3
Epididymis fat weight1.32.93.61.7-1.81.7-1.71.9-1.81.8-1.3
Glucose0.20.30.50.5-0.50.4-0.50.7-0.60.5-0.5
Heart weight2.23.14.91.6-1.71.6-1.72.2-2.01.8-1.5
Left kidney weight0.72.03.31.3-1.41.3-1.41.8-1.61.4-1.1
Right kidney weight0.61.82.71.2-1.31.2-1.31.6-1.51.3-1.2
Tail length5.115.517.04.0-4.04.0-4.04.1-4.04.0-3.5
Length with tail4.516.717.84.0-4.14.0-4.04.2-4.24.1-4.2
Length without tail1.32.84.61.5-1.61.5-1.61.6-1.71.6-2.2
Liver weight, left0.20.30.4-0.60.6-0.70.6-0.30.4-0.60.3
Liver weight, right0.10.10.20.4-0.30.4-0.30.4-0.20.30.0
Parametrial fat weight0.20.42.2-0.40.4-0.40.4-0.00.4-0.41.5
Retroperitoneal fat weight0.10.42.7-0.20.2-0.20.20.30.2-0.21.6
Intraocular pressure0.10.10.30.3-0.30.3-0.3-0.1-0.20.2-0.6
Extensor digitorum longus weight0.10.20.30.5-0.50.5-0.50.5-0.50.5-0.6
Soleus weight0.00.00.2-0.0-0.0-0.00.00.1-0.10.0-0.4
Tibialis anterior weight0.72.62.91.6-1.61.6-1.61.7-1.71.6-1.3
Tibia length4.813.513.93.7-3.73.7-3.73.7-3.73.7-3.4
Number of licking bursts0.10.10.3-0.10.2-0.10.2-0.60.4-0.20.3
Food consumed during 24 hour testing period0.91.11.2-1.11.0-1.11.1-1.11.0-1.10.9
Times rat made contact with spout0.00.10.1-0.30.2-0.30.3-0.30.1-0.2-0.1
Mean time between licks in bursts0.00.00.20.0-0.00.0-0.00.30.0-0.00.4
Mean num. licks in bursts0.00.00.1-0.1-0.0-0.10.00.4-0.30.0-0.4
Std. dev. time between licks in bursts0.30.40.90.6-0.60.6-0.61.0-0.70.6-0.3
Water consumed over 24 hours0.10.10.3-0.20.2-0.20.2-0.60.3-0.2-0.2
Indifference point 0 sec0.10.10.8-0.1-0.0-0.10.0-0.0-0.30.1-0.9
Indifference point AUC0.50.60.80.8-0.80.8-0.80.9-0.80.8-0.3
Indifference point function ln k0.00.00.10.0-0.10.0-0.10.3-0.20.1-0.1
Indifference point function log k0.00.00.10.0-0.10.0-0.10.3-0.20.1-0.1
Delay discounting total patch changes 0 sec0.10.10.7-0.1-0.0-0.10.00.1-0.30.1-0.8
Delay discounting total patch changes 12 sec0.30.40.50.6-0.70.6-0.70.7-0.70.7-0.4
Delay discounting total patch changes 18 sec0.81.11.3-1.11.1-1.11.1-1.11.0-1.10.7
Delay discounting total patch changes 24 sec1.82.22.6-1.61.5-1.61.6-1.51.4-1.51.2
Delay discounting total patch changes 6 sec0.30.41.30.3-0.50.3-0.40.7-0.70.5-1.1
Delay discounting time to switch 0 sec1.42.12.9-1.31.4-1.31.4-1.61.7-1.51.4
Delay discounting water rate 0 sec2.84.56.01.9-2.11.9-2.02.3-2.42.2-2.2
Delay discounting water rate 12 sec0.00.00.1-0.10.0-0.10.0-0.1-0.20.0-0.3
Delay discounting water rate 18 sec0.30.30.40.5-0.60.5-0.60.6-0.70.6-0.5
Delay discounting water rate 24 sec0.60.81.10.9-0.90.9-0.90.7-0.90.9-1.0
Delay discounting water rate 6 sec2.02.93.61.6-1.71.6-1.71.5-1.81.7-1.9
Locomotor activity0.20.41.00.5-0.50.5-0.50.4-0.50.5-1.0
Locomotor testing distance0.10.20.3-0.40.4-0.40.4-0.50.3-0.3-0.3
Locomotor testing rearing0.20.31.40.3-0.40.3-0.30.3-0.50.4-1.2
Light reinforcement 11.22.13.41.4-1.41.4-1.41.2-1.41.4-1.8
Light reinforcement 20.81.01.51.0-1.01.0-1.00.9-1.01.0-1.2
Reaction time number correct0.10.20.40.4-0.40.4-0.40.3-0.60.5-0.4
Reaction time mean minus median0.70.91.4-1.01.0-1.01.0-1.21.0-1.00.2
Reaction time mean minus median AUC0.50.71.1-0.90.8-0.90.9-1.00.8-0.8-0.1
Reaction time num false alarms1.52.03.31.3-1.41.3-1.31.8-1.51.4-1.3
Reaction time num false alarms AUC1.82.53.61.5-1.61.5-1.51.9-1.71.6-1.4
Reaction time trials correct on left0.10.20.40.4-0.40.4-0.40.3-0.60.5-0.4
Reaction time trials on left0.20.30.50.4-0.50.4-0.50.4-0.70.6-0.5
Reaction time mean0.10.10.60.0-0.00.1-0.0-0.20.10.0-0.8
Reaction time mean AUC0.10.10.5-0.10.1-0.10.1-0.20.1-0.1-0.7
Median of all reaction times0.10.20.80.3-0.30.3-0.30.2-0.20.3-0.9
Reaction time omissions0.40.51.80.5-0.60.5-0.50.6-0.70.6-1.4
Reaction time false alarm rate0.91.32.21.1-1.11.1-1.11.5-1.11.1-1.0
Reaction time premature initiation rate0.10.10.4-0.20.3-0.20.3-0.60.4-0.30.3
Reaction time premature initiations0.00.10.3-0.20.2-0.20.2-0.50.2-0.10.2
Std. dev. reaction times0.30.41.70.5-0.50.5-0.50.2-0.40.5-1.3
Reaction time trials completed0.20.30.50.4-0.50.4-0.50.4-0.70.6-0.5
Reaction time trials AUC0.20.30.50.5-0.60.5-0.50.4-0.70.6-0.6
Social response proportion1.21.32.11.0-1.11.0-1.11.1-1.31.1-1.5
Social responses4.86.36.72.4-2.52.4-2.52.5-2.62.5-2.6
Social time0.60.71.20.8-0.80.8-0.80.8-0.80.8-1.1
Conditioned locomotion3.34.05.21.8-2.01.8-1.92.3-2.22.0-1.9
Cocaine response after cond. corrected0.20.20.3-0.60.5-0.60.5-0.30.4-0.50.3
Cocaine response after cond. not corrected0.30.30.4-0.60.6-0.60.6-0.50.5-0.60.4
Cocaine response before conditioning0.10.10.3-0.20.3-0.20.3-0.60.4-0.3-0.1
Saline control response6.78.911.02.9-3.02.9-3.03.3-3.13.0-2.5
Condit. Reinf. active minus inactive responses2.02.53.81.4-1.51.4-1.51.5-1.71.6-1.9
Condit. Reinf. active-inactive response ratio2.12.22.81.4-1.41.4-1.41.4-1.61.5-1.7
Condit. Reinf. active responses3.34.56.51.9-2.11.9-2.02.0-2.32.1-2.5
Condit. Reinf. inactive responses0.50.61.00.7-0.80.7-0.70.8-0.90.8-1.0
Condit. Reinf. lever presses1.72.33.11.5-1.51.5-1.51.3-1.51.5-1.8
Condit. Reinf. lever reinforcers received2.43.45.11.7-1.81.7-1.71.7-2.01.8-2.3
Pavlov. Cond. lever latency4.46.16.2-2.52.5-2.52.5-2.42.5-2.52.5
Pavlov. Cond. magazine entry latency0.00.10.30.1-0.10.1-0.10.2-0.20.2-0.5
Pavlov. Cond. change in total contacts4.35.96.12.4-2.52.4-2.52.3-2.42.5-2.5
Pavlov. Cond. index score3.44.54.62.1-2.12.1-2.12.1-2.12.1-2.1
Pavlov. Cond. latency score2.63.33.41.8-1.81.8-1.81.8-1.81.8-1.8
Pavlov. Cond. lever contacts4.15.75.92.4-2.42.4-2.42.3-2.42.4-2.4
Pavlov. Cond. magazine entry number0.70.81.3-0.90.9-0.90.9-0.80.9-0.91.2
Pavlov. Cond. intertrial magazine entries1.21.52.0-1.21.2-1.21.2-1.01.2-1.21.4
Pavlov. Cond. lever-magazine prob. diff.3.03.94.01.9-2.01.9-2.02.0-2.02.0-2.0
Pavlov. Cond. response bias4.35.96.42.4-2.42.4-2.42.4-2.52.5-2.5
Conditioned reinforcement - actives0.00.00.00.1-0.10.1-0.1-0.1-0.10.1-0.1
Conditioned reinforcement - inactives0.10.10.40.1-0.30.1-0.20.3-0.50.3-0.6
Conditioned locomotion0.10.10.1-0.30.3-0.30.3-0.30.3-0.3-0.1
Intermittent access intake day 1-15 change0.30.30.50.5-0.50.5-0.50.7-0.60.5-0.4
Intermittent access intake escalation0.10.10.20.2-0.20.2-0.20.3-0.30.2-0.5
Intermittent access intake escalation 20.30.30.3-0.50.5-0.50.5-0.40.5-0.50.5
Intermitt. access day 1 inactive lever presses0.40.40.5-0.70.7-0.70.7-0.70.5-0.60.4
Intermitt. access day 15 inactive lever presses0.10.10.2-0.50.4-0.50.4-0.10.2-0.40.4
Intermitt. access escalation Index0.00.00.20.1-0.10.1-0.10.10.00.00.4
Intermittent access day 1 total infusions0.10.10.4-0.10.2-0.10.2-0.00.3-0.20.6
Intermittent access day 15 total infusions0.00.00.0-0.00.0-0.00.00.1-0.0-0.00.1
Intermittent access terminal intake (last 3 days)0.10.10.2-0.20.2-0.20.20.10.1-0.20.4
Intermittent access total infusions0.10.10.5-0.30.3-0.30.30.00.2-0.30.7
Intermittent access day 1 locomotion0.10.10.2-0.40.4-0.40.4-0.40.3-0.40.1
Intermittent access day 15 total locomotion0.20.30.4-0.70.6-0.70.6-0.30.4-0.50.1
Intermittent access total locomotion0.20.20.2-0.50.5-0.50.5-0.30.4-0.50.2
Intermittent access standard deviation0.20.20.50.4-0.30.4-0.30.2-0.30.3-0.7
Cocaine induced anxiety5.86.67.4-2.72.7-2.72.7-2.72.6-2.61.8
Post-drug Anxiety1.71.92.5-1.51.4-1.51.4-1.61.4-1.40.4
Baseline Anxiety0.80.81.00.9-0.90.9-0.90.8-0.80.9-1.0
Lifetime Intake0.10.10.30.2-0.20.2-0.20.5-0.30.20.3
Incentive Sensitization - Responses0.20.20.50.3-0.30.3-0.30.6-0.30.30.7
Incentive Sensitization - Breakpoint0.10.10.80.1-0.10.1-0.10.4-0.10.00.9
Progressive ratio test 1 active lever presses2.42.53.61.6-1.61.6-1.61.9-1.61.6-0.9
Progressive ratio test 1 breakpoint3.13.24.61.8-1.81.8-1.82.1-1.81.8-1.1
Progressive ratio test 1 inactive lever presses0.10.10.20.2-0.30.2-0.30.4-0.40.3-0.3
Progressive ratio test 2 active lever presses0.10.10.40.2-0.20.2-0.20.6-0.30.20.6
Progressive ratio test 2 breakpoint0.10.20.60.2-0.20.2-0.20.6-0.30.20.8
Progressive ratio test 2 inactive lever presses0.00.00.1-0.1-0.0-0.10.00.2-0.20.00.2
Total sessions with >9 infusions0.50.60.90.8-0.80.8-0.80.9-0.70.7-0.5
Short access day 1 total inactive lever presses0.50.60.9-0.70.8-0.70.7-0.90.8-0.80.7
Short access day 10 total inactive lever presses4.95.45.9-2.42.3-2.42.4-2.22.1-2.32.4
Short access day 1 total infusions0.00.00.10.1-0.10.1-0.10.3-0.10.10.3
Short access day 10 total infusions0.00.00.10.2-0.10.2-0.10.4-0.00.10.3
Short access total infusions0.30.30.60.6-0.60.6-0.60.8-0.50.5-0.1
Short access day 1 locomotion1.41.51.7-1.31.2-1.31.3-1.01.1-1.21.3
Short access day 10 total locomotion0.10.10.70.2-0.20.2-0.2-0.0-0.10.2-0.9
Short access total locomotion0.00.00.3-0.10.1-0.10.1-0.0-0.0-0.1-0.6
Compulsive drug intake3.53.55.1-1.81.9-1.81.8-2.32.0-1.91.4
One hour access (0.3 mA shock)0.10.10.1-0.40.3-0.40.4-0.30.2-0.30.4
One hour access (shock baseline)0.20.20.40.4-0.50.4-0.40.6-0.60.4-0.2
Number of responses in last shaping day0.20.20.3-0.40.4-0.40.4-0.50.4-0.40.4
Context. condit. distance diff. score0.00.00.1-0.20.1-0.20.20.2-0.0-0.1-0.1
Locomotion velocity, session 10.30.41.20.4-0.50.4-0.50.6-0.60.5-1.1
Locomotion distance, session 10.10.10.3-0.1-0.1-0.1-0.00.5-0.30.1-0.5
Locomotion velocity, session 20.10.10.2-0.40.4-0.40.4-0.30.3-0.40.2
Locomotion distance, session 20.70.91.70.7-0.90.7-0.81.3-1.10.9-1.1
Locomotion velocity, session 31.31.52.01.2-1.21.2-1.21.4-1.21.2-1.0
Locomotion distance, session 36.36.89.32.6-2.62.6-2.63.0-2.72.6-2.0
Stereotopy head waving bouts, day 31.41.72.2-1.51.4-1.51.4-1.51.2-1.30.3
Stereotopy head waving duration, day 30.81.01.5-1.11.0-1.11.0-1.20.9-1.00.2
Locomotion velocity, session 70.80.81.20.8-0.90.8-0.81.0-1.00.9-1.1
Locomotion distance, session 70.30.41.00.4-0.50.4-0.51.0-0.70.5-0.8
Stereotopy head waving bouts, day 70.70.81.30.9-0.90.9-0.90.6-0.80.9-1.1
Stereotopy head waving duration, day 70.30.30.50.6-0.60.6-0.60.3-0.50.6-0.7
Locomotion velocity, session 80.10.10.30.1-0.20.1-0.20.6-0.50.3-0.6
Locomotion distance, session 80.91.43.20.8-1.00.8-0.91.8-1.41.0-1.3
Degree of sensitization distance2.52.52.9-1.71.7-1.71.7-1.61.6-1.60.9
Degree of sensitization stereotypy3.03.33.71.9-1.91.9-1.91.6-1.81.9-1.6
Condit. Reinf. active minus inactive responses0.80.91.11.0-1.01.0-1.01.0-1.01.0-0.3
Condit. Reinf. active-inactive response ratio0.60.70.80.8-0.90.8-0.80.9-0.90.9-0.4
Condit. Reinf. active responses0.60.81.01.0-0.91.0-0.91.0-0.80.9-0.2
Condit. Reinf. inactive responses0.00.00.0-0.00.0-0.00.00.1-0.0-0.00.0
Incentive salience index mean0.50.61.00.8-0.80.8-0.81.0-0.70.80.1
Condit. Reinf. lever presses0.10.20.40.4-0.40.4-0.40.6-0.30.30.5
Time in familiar zone, hab. session 11.51.41.5-1.21.2-1.21.2-1.21.2-1.20.9
Time in novel zone, hab. session 10.40.40.50.6-0.60.6-0.60.7-0.70.6-0.6
Total zone transitions, hab. session 10.00.00.30.0-0.10.0-0.10.5-0.20.1-0.0
Total locomotion distance, hab. session 10.00.00.1-0.30.2-0.30.30.10.0-0.2-0.0
Locomotion velocity, hab. session 10.00.00.1-0.10.1-0.10.10.3-0.1-0.00.0
Time in familiar zone, hab. session 21.81.91.9-1.41.4-1.41.4-1.31.4-1.41.3
Time in novel zone, hab. session 21.91.92.11.4-1.41.4-1.41.3-1.41.4-1.4
Total zone transitions, hab. session 22.22.84.11.6-1.71.6-1.62.0-1.71.7-1.4
Total locomotion distance, hab. session 20.30.40.90.4-0.50.4-0.50.9-0.80.6-0.9
Locomotion velocity, hab. session 20.10.10.30.0-0.10.0-0.10.6-0.40.2-0.6
Novel to familiar place preference ratio0.20.30.3-0.60.5-0.60.6-0.50.5-0.50.2
Novelty place preference0.50.50.6-0.80.7-0.80.8-0.70.7-0.70.4
Time in novel zone, NPP test0.30.30.4-0.60.6-0.60.6-0.50.5-0.60.2
Total zone transitions, NPP test0.10.10.40.4-0.40.4-0.40.6-0.40.4-0.2
Total locomotion distance, NPP test0.10.10.2-0.0-0.1-0.0-0.00.5-0.30.1-0.5
Locomotion velocity, NPP test0.00.10.1-0.30.2-0.30.30.10.0-0.2-0.3
Pavlov. Cond. lever latency0.50.72.20.8-0.70.8-0.70.1-0.60.7-1.5
Pavlov. Cond. magazine entry latency0.00.00.10.2-0.20.2-0.20.3-0.20.20.1
Pavlov. Cond. change in total contacts0.00.00.10.1-0.10.1-0.10.3-0.10.10.2
Pavlov. Cond. index score0.10.10.5-0.10.1-0.10.10.20.1-0.10.7
Pavlov. Cond. latency score0.20.31.0-0.40.4-0.40.4-0.00.4-0.41.0
Pavlov. Cond. lever contacts0.10.10.60.0-0.00.0-0.00.5-0.10.00.8
Pavlov. Cond. magazine entry number0.70.91.0-1.01.0-1.01.0-0.90.9-1.00.5
Pavlov. Cond. intertrial magazine entries0.00.10.20.2-0.20.2-0.20.2-0.30.2-0.4
Pavlov. Cond. lever-magazine prob. diff.0.00.10.4-0.10.1-0.10.10.10.1-0.10.6
Pavlov. Cond. response bias0.30.40.80.7-0.70.7-0.70.9-0.70.6-0.1
Bone: apparent density0.20.30.60.4-0.50.4-0.40.8-0.70.5-0.1
Bone surface0.40.81.30.7-0.80.7-0.81.1-1.00.8-0.8
Bone volume0.40.71.10.7-0.80.7-0.81.1-1.00.8-0.6
Bone: connectivity density0.00.10.20.1-0.20.1-0.20.4-0.40.2-0.1
Bone: cortical apparent density1.01.31.61.3-1.21.3-1.21.0-1.01.2-1.1
Bone: cortical area3.14.76.62.1-2.22.1-2.22.6-2.32.2-1.6
Bone: cortical porosity0.40.40.60.8-0.70.8-0.70.6-0.40.60.0
Bone: cortical porosity0.91.01.41.2-1.11.2-1.11.0-0.81.0-0.3
Bone: cortical thickness1.52.43.51.6-1.61.6-1.61.9-1.61.6-0.9
Bone: cortical thickness0.30.40.40.7-0.70.7-0.70.6-0.60.7-0.2
Bone: cortical tissue density0.81.11.31.2-1.11.2-1.10.8-0.91.1-1.0
Bone: elastic displacement0.10.10.10.3-0.30.3-0.30.0-0.10.20.2
Bone: elastic work0.10.10.20.4-0.40.4-0.40.2-0.20.30.0
Bone: endosteal estimation0.40.91.30.9-0.90.9-0.91.1-1.00.9-1.0
Bone: endosteal perimeter1.94.05.21.9-2.01.9-1.92.3-2.12.0-1.8
Bone: final force3.55.77.42.4-2.42.4-2.42.7-2.52.4-1.8
Bone: final moment2.64.35.92.1-2.12.1-2.12.4-2.22.1-1.5
Bone: marrow area0.40.81.20.8-0.90.8-0.81.1-1.00.9-0.9
Bone: maximum diameter4.07.39.52.6-2.72.6-2.73.1-2.92.7-2.3
Bone: maximum force0.61.01.51.0-1.01.0-1.01.2-1.11.0-0.7
Bone: maximum moment0.20.40.70.6-0.60.6-0.60.9-0.70.6-0.4
Bone: minimum diameter1.42.64.11.5-1.61.5-1.62.0-1.71.6-1.1
Bone: periosteal estimation2.24.56.02.1-2.12.1-2.12.5-2.22.1-1.8
Bone: periosteal perimeter2.84.66.72.0-2.12.0-2.12.6-2.32.1-1.8
Bone: post-yield work0.60.81.0-0.90.9-0.90.9-1.00.9-0.90.8
Bone: stiffness1.72.63.81.6-1.61.6-1.62.0-1.71.6-1.4
Bone: tissue strength0.20.20.30.3-0.40.3-0.40.4-0.40.4-0.6
Bone: trabecular number0.40.71.00.8-0.90.8-0.81.0-1.00.9-0.5
Bone: trabecular spacing0.00.10.1-0.20.2-0.20.2-0.30.3-0.20.3
Bone: trabecular thickness0.20.30.60.4-0.50.4-0.50.8-0.60.5-0.4
Bone: trabecular tissue density1.21.72.71.2-1.31.2-1.31.6-1.41.3-1.0
Breakpoint value in progressive ratio session3.23.64.11.9-1.91.9-1.92.0-1.91.9-1.7
Distance traveled before self-admin3.94.15.71.9-2.11.9-2.02.4-2.32.1-1.5
Distance traveled after self-admin2.52.73.31.6-1.61.6-1.61.8-1.81.6-1.6
Delta time in closed arm before/after self-admin0.30.30.7-0.40.5-0.40.5-0.40.5-0.50.8
Delta time in open arm before/after self-admin0.20.20.50.3-0.40.3-0.40.6-0.70.4-0.5
Diff in mean of infusions in LGA sessions0.00.00.30.00.00.00.00.00.1-0.00.5
Extinction: sum of active levers before priming0.70.70.80.9-0.90.9-0.90.8-0.90.9-0.5
Active lever presses in extinction session 60.30.31.2-0.40.4-0.40.4-0.30.4-0.41.1
Delta distance traveled before/after self-admin0.30.30.70.5-0.50.5-0.50.4-0.50.5-0.8
Delta ambulatory time before/after self-admin0.30.30.5-0.50.6-0.50.6-0.60.7-0.60.3
Time in closed arm before self-admin0.20.20.3-0.50.5-0.50.5-0.40.5-0.50.5
Time in closed arm after self-admin0.50.61.6-0.60.7-0.60.6-0.50.8-0.71.3
Time in open arm before self-admin0.10.10.2-0.30.3-0.30.3-0.30.4-0.30.4
Time in open arm after self-admin0.00.00.2-0.1-0.0-0.1-0.00.0-0.30.1-0.5
Sum of active levers in priming session hrs 5-61.00.91.30.9-0.90.9-0.90.9-1.11.0-1.1
Time to tail flick, vehicle, before self-admin2.32.32.6-1.61.6-1.61.6-1.61.5-1.61.0
Time to tail flick, vehicle, after self-admin0.00.00.00.1-0.00.1-0.00.00.00.00.2
Time to tail flick, test, before self-admin1.31.31.51.2-1.21.2-1.21.0-1.11.2-1.0
Time to tail flick, test, after self-admin2.72.82.9-1.71.7-1.71.7-1.71.6-1.71.6
Delta time to tail flick, vehicle, before/after SA3.63.64.31.9-1.91.9-1.92.1-1.91.9-1.5
Delta time to tail flick, test, before/after SA3.53.23.7-1.91.8-1.91.9-1.91.7-1.81.2
Ambulatory time before self-admin3.73.84.61.9-2.01.9-2.02.2-2.12.0-1.5
Ambulatory time after self-admin3.33.74.41.9-1.91.9-1.92.1-2.01.9-1.7
Total heroin consumption3.74.55.42.0-2.12.0-2.12.1-2.12.1-2.3
Area under the delay curve0.10.10.2-0.30.3-0.30.3-0.40.5-0.30.4
Delay disc. indifference point, 0s delay2.62.85.4-1.51.6-1.51.5-1.61.7-1.62.3
Delay disc. indifference point, 16s delay0.50.50.7-0.60.7-0.60.7-0.70.8-0.70.6
Delay disc. indifference point, 2s delay0.00.00.2-0.10.1-0.10.1-0.10.1-0.10.4
Delay disc. indifference point, 24s delay2.12.12.5-1.41.5-1.41.4-1.51.6-1.51.1
Delay disc. indifference point, 4s delay0.10.10.20.4-0.30.4-0.40.3-0.20.30.0
Delay disc. indifference point, 8s delay0.10.10.2-0.10.2-0.10.2-0.50.4-0.30.2
Delay discount exponential model param0.10.10.20.2-0.30.2-0.30.3-0.40.3-0.3
Delay discount hyperbolic model param0.10.10.20.2-0.30.2-0.20.3-0.40.3-0.4
Fecal boli incidents, locomotor time 10.10.10.10.4-0.30.4-0.40.3-0.30.30.1
Change in fecal boli incidents, locomotor task0.10.10.2-0.30.3-0.30.3-0.40.3-0.3-0.0
Time >=10cm from walls, locomotor time 10.10.10.30.4-0.30.4-0.30.2-0.30.3-0.6
Bouts of movement, locomotor time 12.12.35.7-1.31.4-1.31.3-1.41.5-1.42.4
Total resting periods, locomotor time 11.51.74.2-1.01.1-1.01.1-1.31.3-1.22.0
Rest time, locomotor task time 10.20.20.6-0.30.4-0.30.3-0.50.4-0.40.8
Distance moved, locomotor task time 10.10.10.7-0.0-0.0-0.0-0.00.1-0.10.0-0.9
Vertical activity count, locomotor time 10.10.10.50.1-0.10.1-0.10.5-0.30.1-0.7
Time >=10cm from walls, locomotor time 20.00.00.10.00.00.00.00.10.1-0.00.4
Bouts of movement, locomotor time 20.50.52.2-0.40.5-0.40.5-0.60.7-0.51.5
Total resting periods, locomotor time 20.30.41.4-0.30.4-0.30.4-0.60.6-0.41.2
Rest time, locomotor task time 20.20.21.0-0.20.3-0.20.2-1.00.5-0.2-0.3
Distance moved, locomotor task time 20.20.20.3-0.50.4-0.50.50.20.2-0.40.6
Vertical activity count, locomotor time 20.10.10.4-0.20.1-0.20.10.6-0.2-0.10.5
Weight adjusted by age3.23.54.31.8-1.91.8-1.91.9-2.11.9-1.6
Seeking ratio, delayed vs. immediate footshock0.20.20.3-0.40.5-0.40.5-0.50.5-0.5-0.1
Locomotion in novel chamber0.10.10.2-0.30.3-0.30.3-0.40.3-0.3-0.3
Locomotion in novel chamber post-restriction1.21.42.51.1-1.11.1-1.11.1-1.21.1-1.6
Progressive ratio2.12.43.6-1.51.6-1.51.6-1.91.7-1.60.8
Food seeking constrained by brief footshock0.10.10.50.0-0.1-0.0-0.10.7-0.40.2-0.2
Seeking ratio, punishment vs. effort1.82.34.21.4-1.51.3-1.42.0-1.71.5-0.8
Run reversals in cocaine runway, females0.10.10.1-0.30.2-0.30.3-0.20.1-0.2-0.3
Run reversals in cocaine runway, males0.80.71.50.7-0.80.7-0.80.9-0.90.8-1.2
Latency to leave start box in cocaine runway0.70.72.4-0.70.8-0.70.7-0.40.8-0.81.5
Latency to leave start box in cocaine runway, F1.41.63.7-1.11.2-1.11.2-0.91.2-1.21.9
Latency to leave start box in cocaine runway, M0.00.00.10.2-0.20.2-0.20.3-0.20.2-0.0
Cd content in liver0.10.20.4-0.30.4-0.30.4-0.20.4-0.40.6
Co content in liver0.60.70.90.8-0.90.8-0.80.9-0.90.9-0.7
Cu content in liver1.92.32.91.4-1.51.4-1.51.5-1.61.5-1.7
Fe content in liver0.00.00.0-0.20.2-0.20.2-0.00.1-0.1-0.1
K content in liver0.20.20.40.4-0.50.4-0.50.7-0.50.5-0.1
Mg content in liver1.31.42.01.1-1.21.1-1.21.4-1.31.2-0.8
Mn content in liver1.92.12.61.4-1.51.4-1.51.6-1.51.5-1.2
Na content in liver0.10.10.2-0.30.3-0.30.3-0.00.3-0.30.4
Rb content in liver2.43.04.41.5-1.71.5-1.62.1-2.01.7-1.6
Se content in liver0.70.81.20.8-0.90.8-0.80.9-0.90.9-1.1
Sr content in liver0.50.50.60.7-0.70.7-0.70.8-0.70.7-0.3
Zn content in liver0.10.20.40.3-0.40.3-0.40.6-0.40.40.1