Hub : Genes

Lgals12

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	intron excision ratio	chr1:204834342:204836046	0.05	0.03	1.5e-03	0.03	0.02	0.01	0.02	7.3e-04	6.4e-03	1.6e-02	2.6e-03
2	Adipose	intron excision ratio	chr1:204834400:204836046	0.04	0.03	3.9e-03	0.02	0.01	0.01	0.02	1.0e-03	9.9e-03	2.9e-02	2.8e-03
3	Adipose	mRNA stability	ENSRNOG00000021207	0.07	0.04	9.1e-05	0.01	0.03	0.02	0.02	7.0e-02	6.1e-04	3.1e-03	1.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
BMI with tail	0.2	0.6	1.7	-0.2	0.2	1.3
BMI without tail	0.2	0.5	0.6	-0.8	0.8	0.4
Body weight	0.6	2.6	7.1	-0.5	0.5	2.7
Epididymis fat weight	0.1	0.2	0.5	-0.0	0.0	-0.7
Glucose	0.8	1.2	3.6	-0.2	0.2	-1.9
Heart weight	1.8	2.6	4.0	-1.4	1.4	-2.0
Left kidney weight	0.1	0.2	0.3	0.5	-0.5	0.4
Right kidney weight	0.5	1.5	1.5	1.2	-1.2	1.2
Tail length	0.3	0.8	1.6	-0.6	0.6	1.3
Length with tail	0.5	2.0	5.8	-0.3	0.3	2.4
Length without tail	0.5	1.1	3.2	-0.1	0.1	1.8
Liver weight, left	0.6	1.0	1.1	-1.0	1.0	-1.0
Liver weight, right	1.2	2.1	2.6	-1.6	1.6	-1.0
Parametrial fat weight	0.6	1.1	3.3	-0.2	0.2	-1.8
Retroperitoneal fat weight	1.0	3.2	8.7	-0.7	0.7	-2.9
Intraocular pressure	1.9	2.7	3.5	1.9	-1.9	1.0
Extensor digitorum longus weight	1.6	6.3	18.1	0.6	-0.6	4.3
Soleus weight	1.0	3.0	7.9	-0.8	0.8	-2.8
Tibialis anterior weight	3.2	11.1	29.9	1.3	-1.3	5.5
Tibia length	3.5	9.8	11.4	3.0	-3.0	3.4
Number of licking bursts	0.1	0.1	0.1	0.2	-0.2	0.3
Food consumed during 24 hour testing period	0.3	0.4	0.5	0.7	-0.7	0.6
Times rat made contact with spout	0.3	0.3	0.5	-0.7	0.7	0.0
Mean time between licks in bursts	2.3	3.3	4.7	-2.2	2.2	-0.6
Mean num. licks in bursts	0.3	0.4	0.5	-0.7	0.7	-0.5
Std. dev. time between licks in bursts	2.7	3.2	3.8	-2.0	2.0	-1.4
Water consumed over 24 hours	0.2	0.2	0.5	-0.3	0.3	0.7
Indifference point 0 sec	0.1	0.2	0.6	0.2	-0.2	0.8
Indifference point AUC	3.5	4.2	6.7	1.7	-1.7	2.6
Indifference point function ln k	7.2	10.3	15.0	-2.8	2.8	-3.9
Indifference point function log k	7.2	10.3	15.0	-2.8	2.8	-3.9
Delay discounting total patch changes 0 sec	0.1	0.1	0.3	-0.3	0.3	0.5
Delay discounting total patch changes 12 sec	2.6	3.4	8.8	0.9	-0.9	3.0
Delay discounting total patch changes 18 sec	1.0	1.3	2.1	0.9	-0.9	1.4
Delay discounting total patch changes 24 sec	2.2	2.7	7.6	0.5	-0.5	2.8
Delay discounting total patch changes 6 sec	0.2	0.3	0.6	-0.3	0.3	0.8
Delay discounting time to switch 0 sec	0.7	1.0	1.1	1.1	-1.1	0.9
Delay discounting water rate 0 sec	0.4	0.6	0.9	-0.7	0.7	-0.9
Delay discounting water rate 12 sec	4.1	6.1	6.6	-2.4	2.4	-2.6
Delay discounting water rate 18 sec	3.5	4.6	4.7	-2.2	2.2	-2.1
Delay discounting water rate 24 sec	1.6	2.3	3.3	-1.3	1.3	-1.8
Delay discounting water rate 6 sec	3.1	4.5	4.7	-2.2	2.2	-2.0
Locomotor activity	2.2	3.5	3.5	-1.9	1.9	-1.8
Locomotor testing distance	3.7	6.2	6.5	-2.5	2.5	-2.4
Locomotor testing rearing	2.2	3.4	3.6	-1.8	1.8	-1.9
Light reinforcement 1	0.0	0.0	0.1	0.2	-0.2	0.2
Light reinforcement 2	3.4	4.5	6.1	2.5	-2.5	1.2
Reaction time number correct	0.2	0.3	0.5	-0.4	0.4	0.7
Reaction time mean minus median	3.4	4.4	4.7	2.2	-2.2	1.9
Reaction time mean minus median AUC	1.2	1.6	1.6	1.3	-1.3	1.3
Reaction time num false alarms	3.4	4.7	5.5	-2.3	2.3	-1.8
Reaction time num false alarms AUC	2.7	3.8	4.9	-2.2	2.2	-1.3
Reaction time trials correct on left	0.2	0.3	0.5	-0.4	0.4	0.7
Reaction time trials on left	0.2	0.3	0.5	-0.4	0.4	0.7
Reaction time mean	1.2	1.6	2.1	1.5	-1.5	0.8
Reaction time mean AUC	1.2	1.6	2.2	1.5	-1.5	0.7
Median of all reaction times	0.6	0.8	1.0	1.0	-1.0	0.5
Reaction time omissions	0.0	0.1	0.1	0.1	-0.1	0.3
Reaction time false alarm rate	2.1	3.0	3.2	-1.8	1.8	-1.6
Reaction time premature initiation rate	1.6	2.1	2.8	-1.7	1.7	0.8
Reaction time premature initiations	1.7	2.5	2.8	-1.7	1.7	1.3
Std. dev. reaction times	1.5	2.1	2.7	1.6	-1.6	1.0
Reaction time trials completed	0.2	0.3	0.5	-0.4	0.4	0.7
Reaction time trials AUC	0.2	0.3	0.3	-0.5	0.5	0.5
Social response proportion	0.0	0.1	0.1	-0.1	0.1	0.4
Social responses	0.1	0.2	0.2	-0.5	0.5	0.3
Social time	0.2	0.3	0.4	-0.7	0.7	-0.1
Conditioned locomotion	0.1	0.1	0.1	-0.4	0.4	0.4
Cocaine response after cond. corrected	2.9	3.3	4.2	-1.7	1.7	-2.0
Cocaine response after cond. not corrected	1.9	2.1	2.8	-1.4	1.4	-1.7
Cocaine response before conditioning	1.6	1.9	2.4	1.3	-1.3	1.5
Saline control response	0.6	0.7	1.7	-0.5	0.5	1.3
Condit. Reinf. active minus inactive responses	1.1	1.3	1.9	1.4	-1.4	0.4
Condit. Reinf. active-inactive response ratio	3.3	3.5	5.0	2.2	-2.2	0.5
Condit. Reinf. active responses	0.2	0.3	0.3	0.5	-0.5	0.5
Condit. Reinf. inactive responses	1.3	1.6	2.4	-1.6	1.6	-0.4
Condit. Reinf. lever presses	1.4	2.0	3.1	1.2	-1.2	1.8
Condit. Reinf. lever reinforcers received	0.5	0.7	0.8	0.8	-0.8	0.9
Pavlov. Cond. lever latency	0.6	0.8	1.3	-0.8	0.8	-1.1
Pavlov. Cond. magazine entry latency	1.8	2.1	5.4	0.7	-0.7	2.3
Pavlov. Cond. change in total contacts	3.1	4.4	6.0	1.9	-1.9	2.5
Pavlov. Cond. index score	2.7	3.5	6.2	1.5	-1.5	2.5
Pavlov. Cond. latency score	2.5	3.2	5.4	1.5	-1.5	2.3
Pavlov. Cond. lever contacts	0.7	1.0	1.6	0.8	-0.8	1.3
Pavlov. Cond. magazine entry number	4.0	4.9	10.9	-1.4	1.4	-3.3
Pavlov. Cond. intertrial magazine entries	0.3	0.4	1.0	0.2	-0.2	-1.0
Pavlov. Cond. lever-magazine prob. diff.	2.7	3.5	6.5	1.4	-1.4	2.5
Pavlov. Cond. response bias	1.4	2.0	3.9	1.0	-1.0	2.0
Conditioned reinforcement - actives	1.5	1.5	2.2	1.5	-1.5	-0.3
Conditioned reinforcement - inactives	1.1	1.3	1.9	1.4	-1.4	-0.2
Conditioned locomotion	0.6	0.7	1.8	0.4	-0.4	-1.3
Intermittent access intake day 1-15 change	2.1	2.0	2.9	1.7	-1.7	0.5
Intermittent access intake escalation	1.7	1.7	2.3	1.5	-1.5	0.6
Intermittent access intake escalation 2	2.6	2.6	3.0	1.7	-1.7	1.3
Intermitt. access day 1 inactive lever presses	0.4	0.5	1.1	0.4	-0.4	-1.0
Intermitt. access day 15 inactive lever presses	1.2	1.3	1.8	1.3	-1.3	0.7
Intermitt. access escalation Index	2.3	2.0	2.1	-1.5	1.5	-1.3
Intermittent access day 1 total infusions	0.9	1.0	3.0	-0.0	0.0	-1.7
Intermittent access day 15 total infusions	1.4	1.5	1.6	1.3	-1.3	-1.2
Intermittent access terminal intake (last 3 days)	1.8	1.9	2.9	1.7	-1.7	-0.2
Intermittent access total infusions	0.9	0.9	1.1	1.0	-1.0	-0.8
Intermittent access day 1 locomotion	1.2	1.3	2.7	-0.7	0.7	-1.6
Intermittent access day 15 total locomotion	0.5	0.6	0.8	0.9	-0.9	-0.3
Intermittent access total locomotion	0.9	1.0	1.4	1.2	-1.2	-0.5
Intermittent access standard deviation	0.8	0.8	1.2	1.1	-1.1	-0.1
Cocaine induced anxiety	0.8	0.9	1.0	1.0	-1.0	0.8
Post-drug Anxiety	2.1	2.4	2.4	1.5	-1.5	1.5
Baseline Anxiety	0.4	0.4	1.0	-0.3	0.3	1.0
Lifetime Intake	0.5	0.5	1.5	0.3	-0.3	-1.2
Incentive Sensitization - Responses	0.9	0.9	1.2	1.1	-1.1	0.7
Incentive Sensitization - Breakpoint	1.0	1.0	1.3	1.2	-1.2	0.6
Progressive ratio test 1 active lever presses	0.6	0.6	1.6	0.3	-0.3	-1.3
Progressive ratio test 1 breakpoint	0.6	0.7	1.7	0.4	-0.4	-1.3
Progressive ratio test 1 inactive lever presses	0.4	0.4	0.5	-0.7	0.7	-0.5
Progressive ratio test 2 active lever presses	1.0	1.0	1.2	1.1	-1.1	-0.8
Progressive ratio test 2 breakpoint	1.1	1.2	1.2	1.1	-1.1	-1.0
Progressive ratio test 2 inactive lever presses	0.8	1.0	1.3	1.2	-1.2	-0.5
Total sessions with >9 infusions	1.5	1.6	3.7	-0.8	0.8	-1.9
Short access day 1 total inactive lever presses	1.0	1.1	2.4	-0.7	0.7	-1.6
Short access day 10 total inactive lever presses	3.1	3.5	5.6	-1.5	1.5	-2.4
Short access day 1 total infusions	1.2	1.2	2.6	-0.8	0.8	-1.6
Short access day 10 total infusions	0.5	0.5	1.4	-0.3	0.3	-1.2
Short access total infusions	1.1	1.2	2.3	-0.8	0.8	-1.5
Short access day 1 locomotion	0.5	0.6	0.7	-0.7	0.7	-0.8
Short access day 10 total locomotion	0.1	0.1	0.3	-0.2	0.2	-0.6
Short access total locomotion	0.3	0.3	0.4	-0.6	0.6	-0.6
Compulsive drug intake	3.2	3.2	4.8	-2.2	2.2	0.1
One hour access (0.3 mA shock)	1.1	1.3	2.9	0.7	-0.7	-1.7
One hour access (shock baseline)	3.1	3.6	4.7	2.2	-2.2	-1.1
Number of responses in last shaping day	1.0	1.0	1.4	-1.2	1.2	-0.6
Context. condit. distance diff. score	0.6	0.7	1.5	-0.6	0.6	-1.2
Locomotion velocity, session 1	0.8	0.8	1.0	-0.9	0.9	-1.0
Locomotion distance, session 1	0.2	0.3	0.4	-0.6	0.6	-0.3
Locomotion velocity, session 2	0.4	0.5	1.5	0.1	-0.1	1.2
Locomotion distance, session 2	0.5	0.8	1.0	-1.0	1.0	-0.5
Locomotion velocity, session 3	0.2	0.2	0.2	-0.4	0.4	-0.5
Locomotion distance, session 3	0.6	0.7	0.9	-1.0	1.0	-0.4
Stereotopy head waving bouts, day 3	0.6	0.8	1.4	-0.7	0.7	-1.2
Stereotopy head waving duration, day 3	0.2	0.2	0.7	0.1	-0.1	-0.8
Locomotion velocity, session 7	0.1	0.1	0.3	-0.2	0.2	-0.5
Locomotion distance, session 7	1.4	1.8	1.8	-1.3	1.3	-1.3
Stereotopy head waving bouts, day 7	1.5	1.7	2.2	1.5	-1.5	0.8
Stereotopy head waving duration, day 7	2.4	2.9	3.7	1.6	-1.6	1.9
Locomotion velocity, session 8	0.7	0.9	0.9	-1.0	1.0	-0.9
Locomotion distance, session 8	0.3	0.5	1.2	-0.3	0.3	-1.1
Degree of sensitization distance	0.2	0.2	0.4	-0.3	0.3	-0.7
Degree of sensitization stereotypy	2.6	2.9	2.9	1.7	-1.7	1.7
Condit. Reinf. active minus inactive responses	0.5	0.5	1.1	0.5	-0.5	1.0
Condit. Reinf. active-inactive response ratio	0.2	0.3	0.4	0.4	-0.4	0.7
Condit. Reinf. active responses	1.0	1.2	1.6	1.0	-1.0	1.3
Condit. Reinf. inactive responses	0.5	0.5	0.7	0.8	-0.8	0.5
Incentive salience index mean	0.5	0.6	1.1	0.5	-0.5	1.1
Condit. Reinf. lever presses	0.4	0.6	0.9	0.7	-0.7	1.0
Time in familiar zone, hab. session 1	0.3	0.2	0.3	-0.6	0.6	-0.2
Time in novel zone, hab. session 1	0.9	0.9	1.8	-0.6	0.6	-1.3
Total zone transitions, hab. session 1	0.1	0.1	0.2	0.1	-0.1	0.4
Total locomotion distance, hab. session 1	0.1	0.1	0.3	-0.0	0.0	-0.5
Locomotion velocity, hab. session 1	0.0	0.0	0.0	0.1	-0.1	0.0
Time in familiar zone, hab. session 2	2.2	2.3	2.8	-1.7	1.7	-1.1
Time in novel zone, hab. session 2	0.8	0.8	1.0	1.0	-1.0	0.8
Total zone transitions, hab. session 2	0.2	0.3	0.4	-0.6	0.6	0.3
Total locomotion distance, hab. session 2	0.5	0.7	0.9	-0.9	0.9	-0.6
Locomotion velocity, hab. session 2	0.3	0.4	0.4	-0.6	0.6	-0.6
Novel to familiar place preference ratio	2.8	2.9	4.2	1.5	-1.5	2.1
Novelty place preference	2.4	2.5	3.1	1.5	-1.5	1.8
Time in novel zone, NPP test	1.8	1.9	2.7	1.3	-1.3	1.6
Total zone transitions, NPP test	0.1	0.2	0.5	0.0	-0.0	0.7
Total locomotion distance, NPP test	0.4	0.6	0.7	-0.8	0.8	-0.7
Locomotion velocity, NPP test	0.2	0.3	0.4	-0.6	0.6	-0.6
Pavlov. Cond. lever latency	0.5	0.6	1.3	-0.5	0.5	-1.2
Pavlov. Cond. magazine entry latency	0.7	0.9	1.7	0.7	-0.7	1.3
Pavlov. Cond. change in total contacts	1.9	2.0	2.1	1.5	-1.5	1.3
Pavlov. Cond. index score	0.7	0.9	1.6	0.7	-0.7	1.2
Pavlov. Cond. latency score	0.3	0.4	0.9	0.5	-0.5	0.9
Pavlov. Cond. lever contacts	0.1	0.1	0.2	0.0	-0.0	0.4
Pavlov. Cond. magazine entry number	1.4	1.7	2.6	-1.1	1.1	-1.6
Pavlov. Cond. intertrial magazine entries	0.9	1.1	1.3	1.1	-1.1	0.9
Pavlov. Cond. lever-magazine prob. diff.	0.8	1.0	1.9	0.8	-0.8	1.4
Pavlov. Cond. response bias	0.9	1.0	1.9	0.8	-0.8	1.4
Bone: apparent density	0.4	0.6	0.7	0.9	-0.9	0.6
Bone surface	2.9	5.0	5.7	2.2	-2.2	2.4
Bone volume	2.8	4.8	5.4	2.3	-2.3	1.9
Bone: connectivity density	0.8	1.2	2.0	0.9	-0.9	1.4
Bone: cortical apparent density	0.1	0.1	0.4	-0.1	0.1	0.6
Bone: cortical area	1.0	1.5	2.3	1.1	-1.1	1.5
Bone: cortical porosity	0.0	0.0	0.0	0.1	-0.1	-0.0
Bone: cortical porosity	0.0	0.0	0.1	0.0	-0.0	0.2
Bone: cortical thickness	0.7	1.1	3.1	-0.4	0.4	1.8
Bone: cortical thickness	1.1	1.3	2.0	-1.4	1.4	-0.2
Bone: cortical tissue density	0.1	0.2	0.5	-0.1	0.1	0.7
Bone: elastic displacement	1.3	1.5	1.6	-1.2	1.2	-1.3
Bone: elastic work	0.8	1.1	1.6	-1.3	1.3	-0.1
Bone: endosteal estimation	0.4	0.8	1.4	0.7	-0.7	-1.2
Bone: endosteal perimeter	0.9	1.8	2.3	1.5	-1.5	-0.8
Bone: final force	1.1	1.8	3.3	1.0	-1.0	1.8
Bone: final moment	1.1	1.8	3.3	1.0	-1.0	1.8
Bone: marrow area	0.4	0.9	1.8	0.6	-0.6	-1.4
Bone: maximum diameter	1.5	2.7	3.3	1.8	-1.8	1.3
Bone: maximum force	1.8	3.1	4.8	1.5	-1.5	2.2
Bone: maximum moment	1.6	2.7	4.4	1.4	-1.4	2.1
Bone: minimum diameter	0.3	0.5	0.5	0.7	-0.7	-0.6
Bone: periosteal estimation	0.6	1.3	1.8	1.4	-1.4	0.4
Bone: periosteal perimeter	0.6	0.9	1.2	1.1	-1.1	0.6
Bone: post-yield work	1.7	2.4	3.5	1.9	-1.9	0.4
Bone: stiffness	1.3	2.1	2.8	1.3	-1.3	1.7
Bone: tissue strength	0.2	0.2	0.3	0.5	-0.5	0.2
Bone: trabecular number	1.2	1.9	2.0	1.4	-1.4	1.3
Bone: trabecular spacing	1.4	1.8	2.1	-1.5	1.5	-1.1
Bone: trabecular thickness	0.5	0.6	0.9	1.0	-1.0	-0.0
Bone: trabecular tissue density	0.8	1.2	3.4	0.2	-0.2	-1.8
Breakpoint value in progressive ratio session	2.1	2.3	4.1	1.2	-1.2	2.0
Distance traveled before self-admin	2.5	2.6	4.2	1.4	-1.4	2.1
Distance traveled after self-admin	0.9	1.0	1.4	0.9	-0.9	1.2
Delta time in closed arm before/after self-admin	4.0	3.8	5.5	-2.3	2.3	-0.7
Delta time in open arm before/after self-admin	4.0	3.8	4.4	1.9	-1.9	2.1
Diff in mean of infusions in LGA sessions	0.8	0.9	2.5	0.4	-0.4	1.6
Extinction: sum of active levers before priming	1.9	2.0	4.4	0.9	-0.9	2.1
Active lever presses in extinction session 6	3.9	3.8	6.0	1.6	-1.6	2.5
Delta distance traveled before/after self-admin	0.9	0.9	1.2	-0.9	0.9	-1.1
Delta ambulatory time before/after self-admin	1.6	1.7	2.2	-1.2	1.2	-1.5
Time in closed arm before self-admin	1.2	1.3	1.8	1.3	-1.3	0.6
Time in closed arm after self-admin	1.3	1.3	1.8	-1.0	1.0	-1.3
Time in open arm before self-admin	6.3	6.7	7.6	-2.8	2.8	-2.2
Time in open arm after self-admin	0.1	0.1	0.1	-0.3	0.3	0.3
Sum of active levers in priming session hrs 5-6	7.4	7.3	7.8	2.7	-2.7	2.8
Time to tail flick, vehicle, before self-admin	0.4	0.4	0.4	0.6	-0.6	0.6
Time to tail flick, vehicle, after self-admin	0.7	0.7	1.0	-1.0	1.0	-0.4
Time to tail flick, test, before self-admin	1.1	1.1	1.4	-1.2	1.2	-0.8
Time to tail flick, test, after self-admin	0.0	0.0	0.0	0.0	-0.0	-0.1
Delta time to tail flick, vehicle, before/after SA	0.7	0.7	0.9	-0.9	0.9	-0.6
Delta time to tail flick, test, before/after SA	1.3	1.1	1.2	1.0	-1.0	1.1
Ambulatory time before self-admin	4.1	4.3	5.5	1.9	-1.9	2.4
Ambulatory time after self-admin	1.3	1.5	1.6	1.3	-1.3	1.0
Total heroin consumption	1.6	1.9	4.8	0.7	-0.7	2.2
Area under the delay curve	0.4	0.4	0.5	-0.7	0.7	-0.6
Delay disc. indifference point, 0s delay	2.0	2.1	2.7	-1.4	1.4	-1.6
Delay disc. indifference point, 16s delay	0.1	0.1	0.1	0.4	-0.4	0.3
Delay disc. indifference point, 2s delay	0.2	0.2	0.5	-0.1	0.1	-0.7
Delay disc. indifference point, 24s delay	0.9	0.8	1.1	-1.1	1.1	-0.5
Delay disc. indifference point, 4s delay	1.6	1.7	2.2	-1.5	1.5	-0.8
Delay disc. indifference point, 8s delay	1.6	1.7	1.9	-1.3	1.3	-1.4
Delay discount exponential model param	0.4	0.4	0.5	0.7	-0.7	0.6
Delay discount hyperbolic model param	0.4	0.5	0.5	0.7	-0.7	0.6
Fecal boli incidents, locomotor time 1	2.3	2.5	3.3	1.8	-1.8	0.9
Change in fecal boli incidents, locomotor task	4.3	4.1	4.3	-2.0	2.0	-2.1
Time >=10cm from walls, locomotor time 1	1.6	1.6	2.3	1.5	-1.5	-0.4
Bouts of movement, locomotor time 1	1.2	1.3	2.4	0.9	-0.9	1.5
Total resting periods, locomotor time 1	1.5	1.6	2.6	1.1	-1.1	1.6
Rest time, locomotor task time 1	0.2	0.2	0.7	0.0	-0.0	-0.8
Distance moved, locomotor task time 1	0.0	0.0	0.0	-0.1	0.1	0.2
Vertical activity count, locomotor time 1	0.4	0.4	0.9	-0.3	0.3	-1.0
Time >=10cm from walls, locomotor time 2	1.5	1.6	2.1	1.4	-1.4	0.8
Bouts of movement, locomotor time 2	0.6	0.6	1.8	0.2	-0.2	1.3
Total resting periods, locomotor time 2	0.4	0.4	1.0	0.2	-0.2	1.0
Rest time, locomotor task time 2	1.0	1.2	3.5	-0.3	0.3	-1.9
Distance moved, locomotor task time 2	0.4	0.4	1.1	0.3	-0.3	1.1
Vertical activity count, locomotor time 2	0.6	0.7	1.0	-1.0	1.0	-0.4
Weight adjusted by age	1.5	1.6	3.0	1.0	-1.0	1.7
Seeking ratio, delayed vs. immediate footshock	0.1	0.1	0.1	-0.4	0.4	-0.1
Locomotion in novel chamber	1.2	1.5	2.1	1.4	-1.4	-0.5
Locomotion in novel chamber post-restriction	0.5	0.6	1.6	0.4	-0.4	-1.2
Progressive ratio	0.4	0.5	0.5	0.7	-0.7	0.6
Food seeking constrained by brief footshock	0.8	0.9	1.1	-1.0	1.0	-0.8
Seeking ratio, punishment vs. effort	2.0	2.5	2.8	-1.7	1.7	-1.4
Run reversals in cocaine runway, females	3.0	3.0	4.1	-2.0	2.0	-0.9
Run reversals in cocaine runway, males	0.3	0.3	0.6	-0.3	0.3	-0.7
Latency to leave start box in cocaine runway	0.1	0.2	0.4	0.1	-0.1	-0.6
Latency to leave start box in cocaine runway, F	0.1	0.1	0.1	0.3	-0.3	0.1
Latency to leave start box in cocaine runway, M	0.9	0.9	2.6	-0.1	0.1	-1.6
Cd content in liver	0.7	0.8	1.1	1.1	-1.1	-0.4
Co content in liver	3.3	3.8	4.1	-1.9	1.9	-2.0
Cu content in liver	0.0	0.0	0.1	-0.1	0.1	0.2
Fe content in liver	0.4	0.5	0.7	0.8	-0.8	0.3
K content in liver	0.3	0.3	0.7	0.4	-0.4	0.8
Mg content in liver	0.1	0.1	0.1	0.4	-0.4	0.3
Mn content in liver	3.0	3.5	5.1	1.6	-1.6	2.3
Na content in liver	0.8	0.9	1.4	0.8	-0.8	1.2
Rb content in liver	1.0	1.2	2.7	-0.7	0.7	-1.6
Se content in liver	4.2	5.1	6.2	2.5	-2.5	1.7
Sr content in liver	2.8	2.6	6.2	0.9	-0.9	2.5
Zn content in liver	1.3	1.5	4.0	0.4	-0.4	2.0