Hub : Genes

Naa40

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000021179	0.04	0.03	7.4e-03	0.01	0	0	0.01	4.3e-02	1.2e-01	3.1e-01	6.3e-02
2	Adipose	mRNA stability	ENSRNOG00000021179	0.08	0.05	8.4e-06	0.01	0.01	0.02	0.01	1.6e-02	6.7e-03	1.8e-03	2.7e-02
3	Brain	mRNA stability	ENSRNOG00000021179	0.1	0.05	4.9e-09	0.07	0.08	0.08	0.08	2.5e-07	6.9e-08	6.6e-08	3.5e-08
4	OFC	intron excision ratio	chr1:204416185:204417376	0.21	0.11	2.2e-03	0.07	0.03	0.11	0.04	9.2e-03	8.5e-02	1.7e-03	4.7e-02
5	OFC	intron excision ratio	chr1:204417938:204424043	0.2	0.11	3.7e-03	0.06	0.06	0.09	0.05	1.6e-02	1.4e-02	4.1e-03	2.9e-02
6	PL	mRNA stability	ENSRNOG00000021179	0.05	0.04	1.4e-03	0.04	0.03	0.04	0.04	2.4e-04	2.0e-03	1.1e-03	7.6e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6
BMI with tail	2.0	6.6	13.1	1.7	3.1	1.4	-2.0	3.6	2.8
BMI without tail	1.2	2.5	5.8	0.2	2.3	1.4	-1.0	1.1	2.4
Body weight	2.3	9.7	18.0	-0.6	4.2	3.4	-2.9	2.0	4.0
Epididymis fat weight	1.8	4.3	7.0	2.7	-2.5	-2.1	1.3	0.5	-2.5
Glucose	2.3	3.5	5.9	2.4	-1.9	-2.4	1.4	0.9	-1.8
Heart weight	2.4	3.4	6.0	1.5	-2.2	-1.7	2.4	-0.8	-1.9
Left kidney weight	0.4	1.2	2.5	1.1	-1.4	-1.2	0.3	0.3	-1.6
Right kidney weight	0.3	0.9	1.6	0.9	-0.8	-0.8	-0.6	1.1	-1.3
Tail length	1.3	4.1	6.9	-2.3	1.9	2.6	-0.9	-1.6	2.3
Length with tail	1.6	5.7	10.0	-2.1	2.9	3.2	-2.0	-0.1	2.8
Length without tail	0.9	1.9	3.2	-0.6	1.8	1.7	-1.5	0.7	1.5
Liver weight, left	0.2	0.2	1.1	1.0	-0.4	-0.4	0.2	-0.2	-0.1
Liver weight, right	0.2	0.3	1.1	1.1	0.2	-0.0	0.9	0.2	0.3
Parametrial fat weight	2.1	4.1	8.9	3.0	-1.8	-2.3	1.5	1.3	-1.8
Retroperitoneal fat weight	4.2	13.9	20.1	4.1	-4.4	-4.1	3.1	0.1	-4.5
Intraocular pressure	0.7	1.0	2.7	-0.7	-1.2	-1.0	-0.8	-0.1	-1.7
Extensor digitorum longus weight	4.5	18.3	30.4	-2.4	5.5	4.8	-4.2	2.3	5.3
Soleus weight	2.7	8.0	12.3	2.2	-3.5	-3.0	3.1	-1.2	-3.3
Tibialis anterior weight	7.1	24.6	38.4	-3.6	6.2	5.5	-5.3	2.0	5.8
Tibia length	1.1	3.1	10.5	-0.3	1.1	0.7	-3.2	2.5	0.6
Number of licking bursts	0.1	0.2	0.3	-0.2	0.5	0.2	-0.5	0.5	0.3
Food consumed during 24 hour testing period	0.2	0.3	0.6	-0.7	0.1	-0.1	-0.8	0.8	-0.1
Times rat made contact with spout	0.8	0.9	1.5	-1.2	1.1	1.1	-0.1	-0.8	1.1
Mean time between licks in bursts	1.4	2.0	3.2	-1.3	1.2	1.8	0.9	-1.5	1.7
Mean num. licks in bursts	0.2	0.3	1.2	-0.4	-0.2	0.2	0.6	-1.1	0.0
Std. dev. time between licks in bursts	0.8	1.0	2.8	-0.5	0.1	0.6	1.7	-1.4	0.6
Water consumed over 24 hours	1.1	1.3	3.1	-1.8	1.2	1.3	-0.5	-0.4	1.1
Indifference point 0 sec	0.0	0.0	0.1	-0.1	-0.3	0.1	-0.2	0.2	-0.3
Indifference point AUC	3.0	3.6	6.9	-1.2	2.0	1.8	-2.6	1.2	2.1
Indifference point function ln k	5.7	8.0	17.0	2.1	-3.0	-2.4	4.1	-1.9	-2.8
Indifference point function log k	5.7	8.0	17.0	2.1	-3.0	-2.4	4.1	-1.9	-2.8
Delay discounting total patch changes 0 sec	0.1	0.1	0.2	-0.4	-0.1	0.4	0.1	-0.3	-0.1
Delay discounting total patch changes 12 sec	3.9	5.1	7.3	-1.6	2.6	2.7	-2.6	0.9	2.6
Delay discounting total patch changes 18 sec	0.8	1.0	2.7	-0.6	1.0	0.9	-1.7	0.6	1.0
Delay discounting total patch changes 24 sec	2.6	3.3	5.1	-1.7	2.1	2.3	-1.8	1.0	1.8
Delay discounting total patch changes 6 sec	0.6	0.9	1.7	-0.5	1.2	1.2	-0.6	0.6	1.3
Delay discounting time to switch 0 sec	1.1	1.6	5.1	0.6	1.2	0.2	-1.4	2.2	0.9
Delay discounting water rate 0 sec	1.9	3.0	5.1	0.1	-2.3	-1.1	1.9	-1.8	-2.2
Delay discounting water rate 12 sec	4.6	6.8	13.1	0.3	-2.9	-1.8	3.6	-2.9	-2.8
Delay discounting water rate 18 sec	2.1	2.8	7.3	0.6	-1.7	-1.1	2.7	-1.6	-1.6
Delay discounting water rate 24 sec	1.9	2.7	4.8	0.4	-1.8	-1.4	2.2	-1.5	-1.9
Delay discounting water rate 6 sec	2.5	3.6	8.3	0.1	-2.0	-0.9	2.9	-2.3	-1.6
Locomotor activity	1.3	2.0	4.8	0.1	-1.3	-0.5	2.0	-2.2	-1.1
Locomotor testing distance	1.8	2.9	8.5	0.1	-1.4	-0.5	2.9	-2.4	-1.0
Locomotor testing rearing	1.3	2.0	5.0	0.4	-1.4	-0.7	2.2	-1.7	-1.1
Light reinforcement 1	0.1	0.1	0.4	-0.6	-0.4	0.1	0.0	-0.6	-0.2
Light reinforcement 2	2.0	2.7	3.9	1.6	-1.9	-1.8	-0.5	1.6	-2.0
Reaction time number correct	0.5	0.7	1.2	-1.0	0.7	1.1	-0.5	-0.8	0.7
Reaction time mean minus median	2.1	2.7	8.1	-0.4	1.8	0.9	-2.9	1.5	1.3
Reaction time mean minus median AUC	1.2	1.5	4.2	-0.7	1.5	0.9	-2.0	0.5	1.0
Reaction time num false alarms	1.1	1.5	4.6	-0.4	-0.4	0.4	1.9	-2.2	0.2
Reaction time num false alarms AUC	1.0	1.5	4.1	-0.9	0.3	1.1	1.4	-2.0	0.8
Reaction time trials correct on left	0.5	0.7	1.2	-1.0	0.7	1.1	-0.5	-0.8	0.7
Reaction time trials on left	0.6	0.8	1.4	-1.0	0.8	1.2	-0.6	-0.8	0.8
Reaction time mean	0.3	0.4	1.3	0.4	0.0	-0.4	-1.1	0.6	-0.5
Reaction time mean AUC	0.3	0.4	1.3	0.5	-0.0	-0.5	-1.1	0.7	-0.6
Median of all reaction times	0.3	0.4	0.7	0.7	-0.4	-0.6	-0.5	0.5	-0.8
Reaction time omissions	0.5	0.7	1.3	-0.8	1.2	0.9	-1.0	-0.4	0.7
Reaction time false alarm rate	0.6	0.8	2.8	-0.1	-0.4	0.1	1.7	-1.3	0.1
Reaction time premature initiation rate	2.6	3.5	6.7	-1.7	2.2	2.6	0.1	-0.4	2.5
Reaction time premature initiations	4.1	5.9	10.8	-2.6	2.7	3.3	-0.5	-0.9	3.0
Std. dev. reaction times	0.5	0.7	3.0	-0.2	0.7	0.2	-1.7	0.5	0.4
Reaction time trials completed	0.6	0.8	1.4	-1.0	0.8	1.2	-0.6	-0.8	0.8
Reaction time trials AUC	0.4	0.6	1.1	-0.8	0.6	1.0	-0.3	-0.8	0.7
Social response proportion	0.6	0.6	1.2	-0.2	1.1	0.7	-1.0	0.4	0.9
Social responses	0.7	0.9	1.3	-1.1	1.0	1.1	-0.6	-0.9	0.8
Social time	0.5	0.7	1.0	-0.9	1.0	0.8	-0.5	-0.7	0.8
Conditioned locomotion	0.8	1.0	1.9	-0.7	1.4	1.1	-0.6	0.2	1.4
Cocaine response after cond. corrected	1.2	1.3	3.8	1.0	-1.1	-0.9	1.9	-0.6	-0.8
Cocaine response after cond. not corrected	0.8	0.8	2.3	0.9	-0.9	-0.7	1.5	-0.4	-0.6
Cocaine response before conditioning	0.7	0.8	2.7	-0.6	0.8	0.7	-1.6	0.5	0.7
Saline control response	3.0	4.0	6.9	-1.7	2.5	2.4	-1.6	0.3	2.6
Condit. Reinf. active minus inactive responses	0.5	0.7	0.9	0.9	-0.7	-0.9	-0.7	0.7	-0.9
Condit. Reinf. active-inactive response ratio	2.4	2.5	3.7	1.9	-1.4	-1.9	-0.8	1.6	-1.6
Condit. Reinf. active responses	0.1	0.1	0.4	0.2	0.1	-0.1	-0.7	0.3	-0.2
Condit. Reinf. inactive responses	0.8	1.0	1.6	-1.1	1.2	1.3	0.2	-1.0	1.0
Condit. Reinf. lever presses	1.4	1.9	5.5	0.1	1.4	0.8	-2.3	1.5	1.0
Condit. Reinf. lever reinforcers received	0.2	0.3	1.3	-0.1	0.4	0.2	-1.1	0.5	0.1
Pavlov. Cond. lever latency	0.6	0.9	2.3	-0.6	-0.6	-0.3	1.5	-1.4	-0.3
Pavlov. Cond. magazine entry latency	2.7	3.1	5.0	-1.0	2.1	2.1	-2.2	0.5	1.9
Pavlov. Cond. change in total contacts	1.6	2.2	8.1	0.1	0.9	0.6	-2.8	1.9	0.5
Pavlov. Cond. index score	1.9	2.4	7.0	-0.2	1.5	1.2	-2.7	1.6	1.1
Pavlov. Cond. latency score	1.6	2.0	6.1	0.1	1.3	1.0	-2.5	1.6	0.9
Pavlov. Cond. lever contacts	0.5	0.7	2.6	-0.0	0.6	0.5	-1.6	0.8	0.4
Pavlov. Cond. magazine entry number	4.3	5.3	10.6	1.2	-2.6	-2.4	3.3	-1.3	-2.2
Pavlov. Cond. intertrial magazine entries	0.6	0.8	1.6	0.6	-1.0	-1.3	0.7	-0.4	-1.1
Pavlov. Cond. lever-magazine prob. diff.	2.2	2.8	7.5	-0.4	1.7	1.4	-2.7	1.5	1.4
Pavlov. Cond. response bias	1.3	1.8	5.2	-0.4	1.4	1.2	-2.3	1.1	1.0
Conditioned reinforcement - actives	0.8	0.8	1.4	0.9	-0.9	-1.2	-0.4	0.9	-1.0
Conditioned reinforcement - inactives	4.0	4.5	9.4	1.7	-2.6	-2.5	0.9	0.9	-3.1
Conditioned locomotion	6.2	7.4	13.7	2.0	-3.6	-2.9	2.2	0.2	-3.7
Intermittent access intake day 1-15 change	0.5	0.5	1.0	0.1	-0.8	-0.7	-0.7	0.1	-1.0
Intermittent access intake escalation	0.4	0.4	0.9	0.2	-0.8	-0.6	-0.6	0.0	-0.9
Intermittent access intake escalation 2	0.3	0.3	1.1	-0.4	-0.4	-0.1	-1.1	0.3	-0.6
Intermitt. access day 1 inactive lever presses	1.8	2.0	3.3	1.3	-1.7	-1.7	1.0	0.3	-1.8
Intermitt. access day 15 inactive lever presses	2.6	2.8	5.1	1.7	-2.2	-1.7	0.5	1.1	-2.3
Intermitt. access escalation Index	1.9	1.7	3.9	1.0	-1.4	-1.0	2.0	-0.8	-1.3
Intermittent access day 1 total infusions	7.1	8.1	17.0	4.1	-2.7	-3.1	2.0	1.6	-2.9
Intermittent access day 15 total infusions	7.7	8.6	13.2	3.6	-3.3	-3.4	1.4	1.1	-3.6
Intermittent access terminal intake (last 3 days)	6.4	7.0	13.9	3.7	-2.6	-2.8	0.5	1.8	-3.1
Intermittent access total infusions	6.0	6.7	13.5	3.7	-2.6	-2.8	1.1	1.5	-2.9
Intermittent access day 1 locomotion	4.9	5.0	11.9	3.4	-1.9	-2.1	2.1	1.3	-2.0
Intermittent access day 15 total locomotion	4.5	4.8	7.6	2.8	-2.5	-2.3	1.0	1.2	-2.7
Intermittent access total locomotion	7.7	8.7	17.7	4.2	-2.9	-2.9	1.3	2.4	-3.1
Intermittent access standard deviation	0.8	0.9	2.2	0.7	-1.3	-1.0	-0.1	-0.1	-1.5
Cocaine induced anxiety	0.2	0.2	0.6	0.3	0.1	-0.1	-0.7	0.8	-0.0
Post-drug Anxiety	0.8	0.9	2.7	-0.2	1.0	0.5	-1.6	0.9	0.8
Baseline Anxiety	1.6	1.7	2.9	-1.2	1.5	1.7	-1.1	-0.6	1.5
Lifetime Intake	5.1	5.7	12.7	3.6	-2.4	-2.5	1.3	0.9	-2.6
Incentive Sensitization - Responses	0.9	0.9	1.6	1.2	-1.0	-0.8	-0.1	1.0	-1.1
Incentive Sensitization - Breakpoint	1.2	1.2	1.8	1.3	-1.2	-1.0	-0.0	1.1	-1.3
Progressive ratio test 1 active lever presses	2.8	2.9	4.9	1.7	-2.0	-2.1	1.2	0.0	-2.2
Progressive ratio test 1 breakpoint	2.4	2.5	4.4	1.5	-1.8	-2.0	1.0	0.1	-2.1
Progressive ratio test 1 inactive lever presses	0.7	0.8	1.5	0.7	-1.0	-0.6	1.1	-0.4	-1.2
Progressive ratio test 2 active lever presses	4.7	5.0	7.9	2.6	-2.6	-2.6	1.0	1.0	-2.8
Progressive ratio test 2 breakpoint	5.0	5.5	9.5	2.3	-3.0	-2.8	1.3	0.6	-3.1
Progressive ratio test 2 inactive lever presses	6.8	7.8	15.0	3.0	-3.3	-3.1	1.4	0.9	-3.9
Total sessions with >9 infusions	2.8	3.0	7.3	2.7	-1.5	-1.8	1.7	0.5	-1.6
Short access day 1 total inactive lever presses	3.7	4.1	5.9	2.0	-2.4	-2.1	2.1	0.0	-2.4
Short access day 10 total inactive lever presses	2.6	2.9	6.7	0.7	-1.9	-1.5	2.6	-1.1	-1.7
Short access day 1 total infusions	3.4	3.6	7.7	2.8	-1.9	-1.9	1.7	0.0	-2.0
Short access day 10 total infusions	3.3	3.7	11.2	3.3	-1.7	-1.8	1.2	1.0	-1.6
Short access total infusions	2.5	2.8	8.2	2.9	-1.4	-1.5	1.4	0.3	-1.4
Short access day 1 locomotion	2.6	2.7	7.4	2.7	-1.5	-1.4	1.5	0.7	-1.5
Short access day 10 total locomotion	1.8	2.0	4.3	2.1	-1.4	-1.2	1.2	1.0	-1.3
Short access total locomotion	2.1	2.1	5.4	2.3	-1.3	-1.1	1.4	1.1	-1.2
Compulsive drug intake	4.7	4.6	8.8	-3.0	1.9	2.5	0.1	-1.9	2.3
One hour access (0.3 mA shock)	7.9	9.1	15.2	3.0	-3.7	-3.5	2.1	0.7	-3.9
One hour access (shock baseline)	8.9	10.3	17.6	3.6	-3.7	-3.9	1.1	1.4	-4.2
Number of responses in last shaping day	0.7	0.7	1.4	0.2	-0.9	-0.2	1.2	-1.0	-1.1
Context. condit. distance diff. score	0.9	1.1	2.2	1.0	-1.2	-1.0	1.5	-0.1	-0.9
Locomotion velocity, session 1	0.1	0.1	0.5	0.2	0.3	0.1	0.7	-0.3	0.3
Locomotion distance, session 1	0.2	0.3	0.6	0.8	0.6	0.3	0.2	0.6	0.7
Locomotion velocity, session 2	1.5	1.8	3.2	-0.5	1.8	1.5	-1.2	0.8	1.7
Locomotion distance, session 2	0.2	0.3	0.9	0.1	0.9	0.6	0.2	-0.2	0.9
Locomotion velocity, session 3	1.1	1.3	4.4	2.1	-0.6	-0.9	0.9	1.0	-0.6
Locomotion distance, session 3	0.1	0.1	0.2	0.4	-0.1	-0.1	0.5	0.0	-0.2
Stereotopy head waving bouts, day 3	1.4	1.6	4.7	2.2	-0.8	-1.2	1.3	0.9	-0.7
Stereotopy head waving duration, day 3	0.9	1.1	2.3	1.5	-1.0	-1.2	0.9	0.5	-1.1
Locomotion velocity, session 7	1.0	1.1	3.1	1.8	-1.1	-1.0	0.7	0.6	-0.8
Locomotion distance, session 7	0.3	0.4	1.7	0.7	-0.3	-0.2	1.3	0.0	0.0
Stereotopy head waving bouts, day 7	0.6	0.7	1.4	1.2	-0.5	-0.8	-0.8	0.9	-0.7
Stereotopy head waving duration, day 7	0.9	1.1	3.7	0.2	0.9	0.7	-1.9	1.0	0.7
Locomotion velocity, session 8	0.7	0.8	1.9	-0.5	1.3	0.8	0.0	-0.5	1.4
Locomotion distance, session 8	0.5	0.8	2.7	1.6	-0.4	-0.9	0.7	0.8	-0.3
Degree of sensitization distance	0.4	0.4	0.9	1.0	-0.2	-0.4	0.7	0.8	0.0
Degree of sensitization stereotypy	0.7	0.7	3.0	0.5	0.4	0.1	-1.7	0.9	0.2
Condit. Reinf. active minus inactive responses	0.2	0.2	0.4	-0.5	0.5	0.6	-0.4	-0.1	0.5
Condit. Reinf. active-inactive response ratio	0.2	0.3	0.7	-0.9	0.3	0.5	-0.4	-0.6	0.2
Condit. Reinf. active responses	0.1	0.1	0.3	0.2	-0.0	0.1	-0.5	0.5	-0.0
Condit. Reinf. inactive responses	0.6	0.7	1.8	1.3	-0.6	-0.8	-0.2	1.1	-0.5
Incentive salience index mean	0.2	0.3	0.4	-0.1	0.6	0.6	-0.5	0.5	0.6
Condit. Reinf. lever presses	0.3	0.4	1.1	0.5	0.6	0.3	-0.8	1.0	0.4
Time in familiar zone, hab. session 1	0.1	0.1	0.3	0.5	-0.3	-0.2	0.5	-0.0	-0.3
Time in novel zone, hab. session 1	0.3	0.3	1.1	-0.1	-0.3	-0.3	1.0	-0.7	-0.1
Total zone transitions, hab. session 1	0.3	0.4	0.8	-0.3	0.9	0.6	-0.7	0.2	0.6
Total locomotion distance, hab. session 1	0.6	0.8	1.8	1.3	-0.7	-1.0	0.6	0.6	-0.8
Locomotion velocity, hab. session 1	0.1	0.2	0.5	0.7	-0.2	-0.5	0.2	0.4	-0.4
Time in familiar zone, hab. session 2	0.9	1.0	2.6	-0.8	0.5	0.8	1.0	-1.6	0.8
Time in novel zone, hab. session 2	0.4	0.4	1.8	0.4	-0.1	-0.4	-0.6	1.4	-0.3
Total zone transitions, hab. session 2	0.5	0.6	1.6	0.4	1.3	0.8	-0.5	0.6	1.0
Total locomotion distance, hab. session 2	0.3	0.4	1.2	1.1	0.1	-0.4	0.7	0.5	-0.1
Locomotion velocity, hab. session 2	0.5	0.6	2.0	1.4	-0.2	-0.8	0.6	0.7	-0.5
Novel to familiar place preference ratio	1.3	1.3	4.6	0.0	0.8	0.6	-2.1	1.4	0.6
Novelty place preference	0.9	0.9	3.3	0.1	0.4	0.3	-1.8	1.3	0.3
Time in novel zone, NPP test	0.7	0.7	2.5	0.2	0.4	0.4	-1.6	1.2	0.4
Total zone transitions, NPP test	1.0	1.5	3.1	-0.2	1.8	1.1	-1.3	0.8	1.5
Total locomotion distance, NPP test	0.1	0.2	0.8	0.9	0.1	-0.2	0.5	0.2	-0.0
Locomotion velocity, NPP test	0.1	0.1	0.4	0.7	0.2	-0.3	0.3	0.1	-0.1
Pavlov. Cond. lever latency	0.3	0.4	1.1	-0.2	-0.7	-0.5	0.7	-1.1	-0.6
Pavlov. Cond. magazine entry latency	0.4	0.5	1.6	0.4	0.5	0.3	-0.9	1.3	0.4
Pavlov. Cond. change in total contacts	0.6	0.7	2.1	0.4	-0.1	-0.4	-1.2	1.5	-0.4
Pavlov. Cond. index score	0.2	0.3	0.8	-0.2	0.5	0.4	-0.9	0.7	0.3
Pavlov. Cond. latency score	0.2	0.2	0.5	0.0	0.4	0.3	-0.6	0.7	0.3
Pavlov. Cond. lever contacts	0.1	0.1	0.2	0.2	0.3	0.3	-0.0	0.5	0.3
Pavlov. Cond. magazine entry number	0.4	0.5	1.9	0.5	-0.5	-0.4	1.4	-0.6	-0.2
Pavlov. Cond. intertrial magazine entries	0.4	0.5	1.2	-0.4	-1.1	-0.4	-0.2	-0.6	-1.0
Pavlov. Cond. lever-magazine prob. diff.	0.4	0.5	1.1	-0.3	0.7	0.5	-1.1	0.9	0.5
Pavlov. Cond. response bias	0.2	0.3	0.8	-0.2	0.3	0.4	-0.9	0.7	0.1
Bone: apparent density	0.5	0.8	2.3	1.1	0.6	0.1	-0.9	1.5	0.6
Bone surface	3.0	5.3	11.0	0.6	2.3	1.1	-3.3	3.2	1.9
Bone volume	1.7	2.8	7.7	1.1	1.0	0.2	-2.5	2.8	0.8
Bone: connectivity density	1.5	2.3	4.0	0.3	1.7	1.1	-1.8	2.0	1.6
Bone: cortical apparent density	0.6	0.7	1.8	-1.3	0.6	1.0	-0.3	-0.8	0.7
Bone: cortical area	0.6	0.8	1.9	-0.1	0.8	0.6	-1.4	1.3	0.5
Bone: cortical porosity	0.0	0.0	0.1	-0.1	0.2	0.1	-0.3	-0.3	0.1
Bone: cortical porosity	0.4	0.4	0.6	-0.5	0.8	0.7	-0.7	-0.4	0.7
Bone: cortical thickness	2.7	4.5	7.8	-2.5	2.3	2.8	-1.3	-0.9	2.3
Bone: cortical thickness	1.1	1.2	2.0	-1.2	1.0	1.4	0.4	-1.1	1.2
Bone: cortical tissue density	0.7	0.9	2.2	-1.5	0.7	1.2	-0.3	-0.9	0.8
Bone: elastic displacement	1.4	1.6	4.2	-0.8	-0.9	-0.1	1.9	-2.1	-0.5
Bone: elastic work	1.2	1.6	2.7	-1.4	1.3	1.6	0.4	-1.1	1.4
Bone: endosteal estimation	2.3	4.9	10.9	3.3	-1.4	-2.5	0.6	2.7	-1.6
Bone: endosteal perimeter	3.3	6.8	13.7	3.7	-1.8	-3.1	0.0	3.1	-2.2
Bone: final force	1.8	2.9	4.4	-0.2	2.1	1.3	-2.0	2.0	1.8
Bone: final moment	1.6	2.7	3.8	-0.2	2.0	1.3	-2.0	1.9	1.7
Bone: marrow area	2.3	4.9	10.9	3.3	-1.5	-2.5	0.7	2.6	-1.6
Bone: maximum diameter	0.9	1.6	5.5	1.0	0.2	-0.5	-1.6	2.3	-0.2
Bone: maximum force	2.4	4.1	10.1	0.8	2.0	0.9	-2.5	3.2	1.7
Bone: maximum moment	2.0	3.5	8.6	0.7	1.8	0.9	-2.3	2.9	1.6
Bone: minimum diameter	2.0	3.6	7.5	2.7	-1.3	-2.0	0.5	2.4	-1.5
Bone: periosteal estimation	1.2	2.4	7.4	2.1	-0.4	-1.3	-0.7	2.7	-0.7
Bone: periosteal perimeter	0.8	1.3	4.2	1.4	0.0	-0.7	-1.0	2.0	-0.3
Bone: post-yield work	3.8	5.2	15.2	3.2	-0.2	-1.8	-1.6	3.9	-0.6
Bone: stiffness	1.7	2.7	5.8	0.5	1.7	0.6	-2.4	2.4	1.3
Bone: tissue strength	0.1	0.1	0.3	0.1	-0.2	-0.2	-0.5	-0.0	-0.3
Bone: trabecular number	0.8	1.3	4.3	0.9	0.5	-0.0	-1.5	2.1	0.3
Bone: trabecular spacing	0.9	1.1	3.9	-0.9	-0.2	0.4	1.3	-2.0	0.0
Bone: trabecular thickness	0.7	0.9	1.7	1.3	-1.1	-1.1	0.2	0.5	-1.0
Bone: trabecular tissue density	2.3	3.2	5.3	1.1	-2.3	-2.0	1.3	-1.3	-2.3
Breakpoint value in progressive ratio session	2.0	2.3	4.9	-0.9	1.7	1.6	-2.2	0.4	1.5
Distance traveled before self-admin	0.6	0.6	2.7	0.2	0.5	0.6	-1.6	0.7	0.3
Distance traveled after self-admin	0.2	0.2	1.1	-0.3	0.2	0.2	-1.0	0.1	-0.1
Delta time in closed arm before/after self-admin	1.0	1.0	2.5	-0.2	0.1	1.2	1.6	-1.1	0.9
Delta time in open arm before/after self-admin	0.8	0.7	2.7	-0.7	0.3	0.2	-1.6	0.9	-0.4
Diff in mean of infusions in LGA sessions	0.9	1.0	2.4	-1.0	0.6	1.5	-1.1	-0.9	0.7
Extinction: sum of active levers before priming	3.2	3.3	4.9	-1.2	2.2	2.0	-2.2	0.8	2.0
Active lever presses in extinction session 6	2.4	2.3	5.9	-1.0	1.4	1.6	-2.4	0.7	1.4
Delta distance traveled before/after self-admin	0.2	0.2	0.6	-0.3	0.1	-0.1	0.8	-0.7	-0.1
Delta ambulatory time before/after self-admin	0.3	0.3	0.9	-0.4	0.2	-0.1	1.0	-0.9	0.1
Time in closed arm before self-admin	0.4	0.5	1.2	0.3	0.2	-0.6	-1.0	1.1	-0.2
Time in closed arm after self-admin	0.3	0.3	1.5	0.3	-0.3	-0.4	1.2	-0.1	-0.1
Time in open arm before self-admin	1.6	1.7	5.0	-0.2	-0.3	0.5	2.2	-2.2	0.3
Time in open arm after self-admin	0.5	0.5	1.7	-1.0	-0.0	0.5	0.0	-1.3	-0.2
Sum of active levers in priming session hrs 5-6	1.8	1.8	7.5	-1.2	0.7	0.8	-2.7	0.7	0.4
Time to tail flick, vehicle, before self-admin	1.1	1.1	3.6	0.9	0.8	0.1	-0.9	1.9	0.8
Time to tail flick, vehicle, after self-admin	1.8	1.9	4.7	-0.1	2.1	1.2	-0.4	0.9	2.2
Time to tail flick, test, before self-admin	0.8	0.8	2.1	1.4	-0.5	-0.6	1.3	0.4	-0.6
Time to tail flick, test, after self-admin	0.1	0.1	0.1	-0.2	0.4	0.1	-0.3	-0.1	0.2
Delta time to tail flick, vehicle, before/after SA	0.6	0.5	1.3	-0.4	1.1	0.6	0.1	-0.3	1.2
Delta time to tail flick, test, before/after SA	1.7	1.6	4.0	-2.0	0.9	1.0	-1.6	-0.6	0.9
Ambulatory time before self-admin	0.7	0.8	3.6	0.1	0.2	0.3	-1.9	0.9	-0.1
Ambulatory time after self-admin	0.5	0.5	0.9	0.7	-0.5	-0.7	-0.7	0.8	-0.9
Total heroin consumption	4.3	5.1	7.2	-2.0	2.7	2.7	-2.4	-0.3	2.6
Area under the delay curve	0.2	0.2	0.5	0.7	0.2	-0.0	0.6	0.3	0.4
Delay disc. indifference point, 0s delay	0.5	0.6	1.7	1.2	-0.1	-0.4	1.3	0.0	0.2
Delay disc. indifference point, 16s delay	0.7	0.7	1.0	1.0	-1.0	-0.8	0.4	0.6	-1.0
Delay disc. indifference point, 2s delay	0.3	0.3	0.8	0.8	-0.1	-0.6	0.3	0.9	-0.0
Delay disc. indifference point, 24s delay	0.4	0.4	0.9	-0.8	0.3	0.5	0.9	-0.5	0.3
Delay disc. indifference point, 4s delay	0.3	0.4	1.3	0.1	0.4	0.4	1.1	-0.4	0.6
Delay disc. indifference point, 8s delay	0.3	0.3	0.9	0.6	0.4	0.0	0.9	-0.5	0.6
Delay discount exponential model param	0.1	0.1	0.3	-0.5	-0.3	-0.0	-0.5	-0.3	-0.4
Delay discount hyperbolic model param	0.2	0.2	0.3	-0.5	-0.4	-0.0	-0.5	-0.4	-0.5
Fecal boli incidents, locomotor time 1	0.8	0.8	2.3	0.5	-0.0	-0.6	-1.5	1.4	-0.3
Change in fecal boli incidents, locomotor task	0.7	0.7	3.3	0.0	0.3	-0.1	1.8	-0.8	0.5
Time >=10cm from walls, locomotor time 1	2.6	2.7	5.6	2.4	-1.1	-2.0	-0.5	1.9	-1.1
Bouts of movement, locomotor time 1	2.0	2.2	6.5	-2.5	1.0	1.4	-1.5	-1.0	0.8
Total resting periods, locomotor time 1	1.4	1.6	4.8	-2.2	0.7	1.1	-1.5	-0.7	0.5
Rest time, locomotor task time 1	0.9	1.0	1.6	-0.2	-1.3	-1.2	0.9	-0.7	-1.2
Distance moved, locomotor task time 1	0.2	0.2	0.5	0.7	0.6	0.3	-0.4	0.5	0.2
Vertical activity count, locomotor time 1	1.0	1.1	1.9	1.4	-1.1	-1.0	0.9	-0.3	-1.3
Time >=10cm from walls, locomotor time 2	0.3	0.3	1.3	-0.2	-0.0	-0.3	-1.1	0.6	-0.1
Bouts of movement, locomotor time 2	0.6	0.6	1.2	-1.0	0.6	1.1	-0.7	-0.4	0.6
Total resting periods, locomotor time 2	0.2	0.3	0.5	-0.6	0.3	0.7	-0.6	-0.3	0.4
Rest time, locomotor task time 2	2.1	2.4	3.8	1.5	-1.8	-2.0	1.5	-0.4	-1.6
Distance moved, locomotor task time 2	1.1	1.3	1.7	-1.3	1.3	1.3	-1.3	-0.2	1.0
Vertical activity count, locomotor time 2	0.8	0.9	2.6	-1.3	0.2	0.7	0.5	-1.6	0.1
Weight adjusted by age	1.8	2.1	2.6	-1.2	1.6	1.3	-1.6	1.4	1.5
Seeking ratio, delayed vs. immediate footshock	0.1	0.1	0.2	-0.4	-0.3	0.0	0.5	-0.2	-0.3
Locomotion in novel chamber	4.0	4.9	8.8	2.2	-2.6	-2.6	0.7	1.2	-3.0
Locomotion in novel chamber post-restriction	2.4	2.8	4.9	1.5	-2.2	-2.0	1.2	-0.3	-2.0
Progressive ratio	1.3	1.5	2.4	0.4	1.5	0.6	-1.6	1.5	1.3
Food seeking constrained by brief footshock	0.3	0.4	0.6	-0.6	0.6	0.5	0.6	-0.6	0.8
Seeking ratio, punishment vs. effort	1.5	1.9	5.2	-0.6	-1.2	-0.3	2.3	-1.9	-0.8
Run reversals in cocaine runway, females	0.7	0.6	1.1	0.7	0.8	0.8	1.0	0.2	1.1
Run reversals in cocaine runway, males	0.1	0.1	0.3	-0.2	0.0	-0.4	0.4	-0.5	-0.4
Latency to leave start box in cocaine runway	0.7	0.8	1.8	1.4	-0.5	-0.9	0.4	1.2	-0.2
Latency to leave start box in cocaine runway, F	0.1	0.1	0.4	0.5	-0.3	-0.1	-0.1	0.6	0.1
Latency to leave start box in cocaine runway, M	0.7	0.7	1.4	1.2	-0.4	-1.2	0.6	0.7	-0.2
Cd content in liver	0.9	1.0	2.2	0.7	-0.9	-1.5	-0.2	0.8	-1.4
Co content in liver	1.9	2.3	6.4	-1.4	-0.8	-0.1	2.1	-2.5	-0.5
Cu content in liver	0.3	0.3	0.9	-0.9	0.5	0.6	-0.5	-0.1	0.5
Fe content in liver	0.3	0.3	0.8	0.3	0.2	-0.2	-0.9	0.9	0.2
K content in liver	1.0	1.0	1.8	0.4	1.1	0.8	-0.7	1.2	1.3
Mg content in liver	0.3	0.4	1.3	0.9	-0.0	-0.1	0.1	1.2	0.2
Mn content in liver	1.5	1.7	4.7	-0.6	1.2	1.1	-2.2	1.2	1.1
Na content in liver	0.6	0.6	1.2	-0.2	0.8	0.5	-1.1	1.0	0.8
Rb content in liver	1.3	1.7	2.2	1.5	-1.4	-1.4	1.5	-0.2	-1.3
Se content in liver	1.0	1.3	3.2	0.5	-0.4	-0.8	-1.7	1.8	-0.8
Sr content in liver	2.9	2.7	4.3	-1.6	1.7	2.1	-1.9	0.3	1.7
Zn content in liver	0.9	1.0	1.7	-0.8	0.9	1.3	-1.2	0.8	1.0