Hub : Genes

Scn1b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000021102 0.23 0.14 4.9e-04 0.07 0.07 0.1 0.08 1.4e-04 1.3e-04 4.4e-06 4.8e-05
2 Brain alternative TSS ENSRNOT00000028653 0.24 0.11 9.9e-08 0.1 0.07 0.07 0.09 3.2e-09 2.6e-07 2.8e-07 6.6e-09
3 Brain alternative TSS ENSRNOT00000092133 0.25 0.12 6.1e-08 0.1 0.08 0.08 0.1 2.0e-09 1.3e-07 1.1e-07 3.8e-09
4 Brain gene expression ENSRNOG00000021102 0.21 0.1 1.6e-08 0.09 0.07 0.07 0.08 1.6e-08 4.7e-07 2.4e-07 7.5e-08
5 Brain isoform ratio ENSRNOT00000028653 0.15 0.08 4.7e-06 0.07 0.06 0.07 0.07 3.8e-07 5.3e-06 9.8e-07 8.1e-07
6 Brain isoform ratio ENSRNOT00000092133 0.16 0.08 2.4e-06 0.08 0.06 0.06 0.07 1.6e-07 2.9e-06 4.6e-06 3.8e-07
7 Brain mRNA stability ENSRNOG00000021102 0.12 0.08 4.0e-06 0.05 0.07 0.04 0.06 1.7e-05 1.0e-06 5.4e-05 8.3e-06
8 IL gene expression ENSRNOG00000021102 0.38 0.17 5.9e-03 0.07 0.1 0.05 0.1 8.5e-03 2.1e-03 2.5e-02 2.7e-03
9 Liver gene expression ENSRNOG00000021102 0.36 0.12 0.0e+00 0.22 0.21 0.21 0.21 8.3e-24 1.4e-22 8.0e-23 2.9e-23
10 PL gene expression ENSRNOG00000021102 0.17 0.11 5.9e-05 0.09 0.07 0.07 0.09 4.3e-07 8.5e-06 8.4e-06 4.0e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail0.00.10.60.2-0.40.40.0-0.30.30.40.80.20.2
BMI without tail0.10.20.50.2-0.70.70.2-0.70.70.50.10.40.3
Body weight1.56.213.5-2.42.1-2.1-1.62.1-2.1-3.5-3.7-2.3-2.3
Epididymis fat weight0.61.52.2-0.71.4-1.4-0.71.5-1.5-0.4-1.3-1.4-1.3
Glucose0.50.81.30.5-1.01.00.9-1.11.10.30.51.11.1
Heart weight2.23.25.2-1.42.1-2.1-1.12.0-2.0-0.3-1.2-2.3-2.3
Left kidney weight1.13.216.9-1.60.9-0.9-0.40.8-0.8-4.1-2.6-1.1-1.1
Right kidney weight1.95.520.8-2.01.6-1.6-0.91.4-1.4-4.6-3.6-2.0-2.0
Tail length1.33.812.7-1.91.4-1.4-1.21.4-1.4-2.7-3.6-1.6-1.6
Length with tail4.115.233.4-3.93.5-3.5-2.63.4-3.4-4.8-5.8-3.6-3.6
Length without tail5.511.918.4-3.23.5-3.5-2.33.4-3.4-3.8-4.3-3.4-3.3
Liver weight, left0.60.92.40.7-1.01.01.6-1.01.0-0.00.71.01.0
Liver weight, right0.20.42.21.2-0.00.01.50.0-0.00.30.20.00.0
Parametrial fat weight2.24.28.91.9-2.22.23.0-2.22.2-1.10.82.12.1
Retroperitoneal fat weight1.03.46.81.7-1.81.82.6-1.81.80.61.81.91.9
Intraocular pressure0.30.40.6-0.4-0.80.8-0.7-0.80.80.60.60.50.5
Extensor digitorum longus weight0.20.92.60.4-0.80.81.3-0.80.8-1.60.50.80.8
Soleus weight0.10.20.80.9-0.30.30.8-0.30.3-0.20.50.40.3
Tibialis anterior weight0.41.42.00.5-1.41.41.4-1.31.3-1.40.31.11.1
Tibia length3.29.115.2-3.02.9-2.9-1.93.0-3.0-2.8-3.9-3.2-3.2
Number of licking bursts0.60.73.30.7-0.40.4-0.2-0.30.31.81.50.40.4
Food consumed during 24 hour testing period1.61.93.2-1.21.4-1.4-1.61.4-1.40.1-1.3-1.7-1.8
Times rat made contact with spout0.30.31.20.6-0.60.61.1-0.50.50.20.20.50.5
Mean time between licks in bursts0.60.81.50.01.1-1.1-0.21.0-1.00.7-0.4-1.2-1.1
Mean num. licks in bursts0.40.52.3-0.40.2-0.20.80.2-0.2-1.5-1.3-0.2-0.2
Std. dev. time between licks in bursts1.11.32.0-0.01.3-1.3-1.31.3-1.31.4-0.4-1.1-1.0
Water consumed over 24 hours1.31.62.4-0.61.3-1.3-0.51.5-1.5-0.8-1.4-1.5-1.5
Indifference point 0 sec0.00.00.2-0.20.0-0.0-0.3-0.10.10.50.1-0.3-0.3
Indifference point AUC0.50.60.80.6-0.90.90.8-0.70.70.10.90.90.9
Indifference point function ln k1.11.52.6-0.21.4-1.4-0.41.4-1.40.1-1.4-1.6-1.6
Indifference point function log k1.11.52.6-0.21.4-1.4-0.41.4-1.40.1-1.4-1.6-1.6
Delay discounting total patch changes 0 sec0.10.10.2-0.40.2-0.2-0.50.1-0.10.3-0.1-0.4-0.4
Delay discounting total patch changes 12 sec0.40.50.60.5-0.70.70.7-0.70.70.50.70.80.8
Delay discounting total patch changes 18 sec0.10.20.5-0.7-0.30.3-0.7-0.40.40.30.30.30.3
Delay discounting total patch changes 24 sec0.81.03.1-1.80.5-0.5-1.60.5-0.5-1.1-0.7-0.7-0.8
Delay discounting total patch changes 6 sec0.10.10.20.3-0.40.40.2-0.40.40.10.40.30.3
Delay discounting time to switch 0 sec4.06.19.41.5-2.92.91.3-3.13.10.42.42.82.8
Delay discounting water rate 0 sec0.91.52.50.61.5-1.50.21.6-1.61.0-0.2-1.4-1.3
Delay discounting water rate 12 sec2.23.34.6-0.82.1-2.1-1.52.1-2.10.4-2.0-2.1-2.0
Delay discounting water rate 18 sec0.40.60.90.80.8-0.80.30.9-0.90.9-0.2-0.7-0.7
Delay discounting water rate 24 sec5.17.110.7-1.13.2-3.2-2.03.3-3.31.1-1.8-3.2-3.1
Delay discounting water rate 6 sec4.97.110.0-1.63.1-3.1-2.13.2-3.2-0.4-2.4-3.1-3.1
Locomotor activity1.21.84.82.1-1.01.02.2-1.11.10.80.81.21.3
Locomotor testing distance0.61.02.81.7-0.70.71.5-0.80.81.10.60.80.9
Locomotor testing rearing0.61.03.81.9-0.30.31.1-0.30.31.90.80.30.5
Light reinforcement 10.30.50.90.50.9-0.9-0.40.7-0.71.0-0.2-0.6-0.5
Light reinforcement 20.60.82.81.70.2-0.21.20.1-0.11.51.1-0.1-0.1
Reaction time number correct0.30.40.70.10.8-0.80.20.8-0.8-0.4-0.6-0.8-0.8
Reaction time mean minus median0.20.20.6-0.7-0.30.3-0.3-0.30.3-0.8-0.40.50.4
Reaction time mean minus median AUC0.30.41.9-0.8-0.20.2-0.3-0.30.3-1.4-0.70.30.2
Reaction time num false alarms0.91.21.80.6-1.31.30.2-1.21.20.81.31.21.2
Reaction time num false alarms AUC1.31.82.60.8-1.61.60.4-1.51.51.11.61.51.4
Reaction time trials correct on left0.30.40.70.10.8-0.80.20.8-0.8-0.4-0.6-0.8-0.8
Reaction time trials on left0.30.40.70.10.8-0.80.30.7-0.7-0.4-0.6-0.8-0.8
Reaction time mean0.10.10.4-0.50.1-0.1-0.60.1-0.10.1-0.7-0.2-0.3
Reaction time mean AUC0.00.00.2-0.1-0.20.2-0.3-0.20.20.2-0.40.10.0
Median of all reaction times0.10.10.3-0.20.1-0.1-0.50.1-0.10.5-0.5-0.3-0.3
Reaction time omissions0.30.40.80.5-0.80.80.7-0.90.90.50.20.60.5
Reaction time false alarm rate1.31.92.80.5-1.71.70.1-1.61.61.11.61.51.5
Reaction time premature initiation rate0.20.20.60.50.4-0.4-0.80.4-0.40.70.2-0.3-0.3
Reaction time premature initiations0.30.40.60.50.7-0.7-0.70.7-0.70.3-0.1-0.7-0.7
Std. dev. reaction times0.30.41.3-1.10.2-0.2-1.00.2-0.2-0.7-0.9-0.2-0.3
Reaction time trials completed0.30.40.70.10.8-0.80.30.7-0.7-0.4-0.6-0.8-0.8
Reaction time trials AUC0.20.20.30.30.5-0.50.50.4-0.4-0.5-0.4-0.5-0.5
Social response proportion1.41.53.6-1.91.2-1.2-0.91.2-1.2-1.6-1.1-0.9-0.9
Social responses0.30.40.8-0.50.9-0.9-0.10.9-0.9-0.8-0.4-0.4-0.5
Social time4.96.48.2-2.12.8-2.8-2.02.9-2.9-1.3-2.7-2.7-2.7
Conditioned locomotion0.70.81.90.3-1.01.00.2-1.01.00.61.40.80.9
Cocaine response after cond. corrected2.62.94.20.5-2.02.01.5-2.12.1-0.51.32.02.0
Cocaine response after cond. not corrected3.33.75.21.0-2.22.22.0-2.32.3-0.21.22.22.3
Cocaine response before conditioning0.60.72.10.00.9-0.9-0.40.9-0.90.1-1.5-0.8-0.8
Saline control response0.10.10.40.6-0.20.20.6-0.30.30.10.00.10.1
Condit. Reinf. active minus inactive responses1.82.23.4-0.41.8-1.8-0.61.8-1.8-0.6-1.7-1.6-1.6
Condit. Reinf. active-inactive response ratio0.10.10.20.00.5-0.50.10.4-0.40.3-0.2-0.2-0.2
Condit. Reinf. active responses3.34.66.3-1.12.5-2.5-1.42.4-2.4-1.2-2.5-2.3-2.3
Condit. Reinf. inactive responses3.24.05.0-1.62.1-2.1-2.12.0-2.0-1.1-2.1-2.2-2.2
Condit. Reinf. lever presses4.25.910.8-1.72.6-2.6-1.32.6-2.6-2.2-3.3-2.3-2.4
Condit. Reinf. lever reinforcers received4.36.08.2-1.42.9-2.9-1.82.8-2.8-1.1-2.8-2.6-2.7
Pavlov. Cond. lever latency4.56.28.91.9-2.82.81.8-2.62.62.13.02.52.6
Pavlov. Cond. magazine entry latency1.61.82.5-0.91.4-1.4-1.01.4-1.4-1.0-1.6-1.5-1.5
Pavlov. Cond. change in total contacts6.49.012.4-2.93.1-3.1-3.02.9-2.9-2.5-3.5-2.9-3.0
Pavlov. Cond. index score4.35.68.0-1.72.6-2.6-1.82.5-2.5-1.8-2.8-2.5-2.5
Pavlov. Cond. latency score4.05.06.9-1.62.4-2.4-1.82.4-2.4-1.7-2.6-2.4-2.4
Pavlov. Cond. lever contacts4.56.38.6-2.02.7-2.7-2.02.6-2.6-2.0-2.9-2.5-2.6
Pavlov. Cond. magazine entry number3.94.87.41.4-2.42.41.5-2.42.41.62.72.32.3
Pavlov. Cond. intertrial magazine entries1.41.72.80.5-1.51.50.6-1.51.50.31.61.61.7
Pavlov. Cond. lever-magazine prob. diff.3.95.17.8-1.52.5-2.5-1.62.4-2.4-1.7-2.8-2.3-2.4
Pavlov. Cond. response bias6.18.510.9-2.23.2-3.2-2.43.1-3.1-2.0-3.3-3.0-3.1
Conditioned reinforcement - actives0.10.10.50.70.2-0.20.20.2-0.20.60.1-0.2-0.2
Conditioned reinforcement - inactives4.44.96.9-1.52.6-2.6-2.12.6-2.60.1-1.3-2.6-2.6
Conditioned locomotion0.30.42.00.70.0-0.00.0-0.00.01.21.4-0.0-0.0
Intermittent access intake day 1-15 change1.51.53.1-1.31.0-1.0-1.21.0-1.0-1.8-1.6-1.0-1.0
Intermittent access intake escalation2.01.93.3-1.41.2-1.2-1.51.2-1.2-1.8-1.7-1.2-1.2
Intermittent access intake escalation 20.30.31.1-0.70.1-0.1-0.60.1-0.1-1.1-0.9-0.1-0.1
Intermitt. access day 1 inactive lever presses1.31.43.2-1.71.0-1.0-1.00.9-0.9-1.8-1.2-0.9-0.9
Intermitt. access day 15 inactive lever presses1.11.21.6-0.91.3-1.3-1.11.3-1.3-0.7-0.5-1.2-1.2
Intermitt. access escalation Index0.30.30.5-0.40.6-0.6-0.70.6-0.60.5-0.1-0.5-0.5
Intermittent access day 1 total infusions0.70.74.20.40.6-0.6-0.70.5-0.52.10.9-0.6-0.6
Intermittent access day 15 total infusions1.71.93.4-0.81.6-1.6-1.81.5-1.50.6-0.6-1.5-1.5
Intermittent access terminal intake (last 3 days)1.11.22.1-0.11.2-1.2-1.51.2-1.21.3-0.2-1.2-1.2
Intermittent access total infusions0.91.03.20.01.0-1.0-1.30.9-0.91.80.1-0.9-0.9
Intermittent access day 1 locomotion1.01.01.6-0.11.1-1.1-1.21.1-1.11.30.5-1.1-1.1
Intermittent access day 15 total locomotion2.42.63.6-0.81.9-1.9-1.91.9-1.90.2-0.7-1.9-1.9
Intermittent access total locomotion0.40.51.80.20.5-0.5-0.70.5-0.51.30.8-0.5-0.5
Intermittent access standard deviation3.43.76.5-2.51.7-1.7-2.41.7-1.7-1.3-2.3-1.7-1.7
Cocaine induced anxiety0.30.42.5-0.70.3-0.3-0.00.3-0.3-1.6-0.3-0.3-0.3
Post-drug Anxiety0.70.81.40.4-1.01.00.8-1.01.0-0.81.21.01.0
Baseline Anxiety0.90.92.00.9-0.80.80.4-0.80.81.41.40.80.8
Lifetime Intake0.60.72.90.30.7-0.7-0.80.7-0.71.70.1-0.7-0.7
Incentive Sensitization - Responses0.70.71.10.21.1-1.1-0.61.0-1.00.4-0.5-1.0-1.0
Incentive Sensitization - Breakpoint0.60.61.00.11.0-1.0-0.61.0-1.00.2-0.5-1.0-1.0
Progressive ratio test 1 active lever presses2.32.43.6-1.41.7-1.7-1.91.7-1.7-0.3-1.1-1.7-1.7
Progressive ratio test 1 breakpoint2.12.23.1-1.41.6-1.6-1.81.6-1.6-0.6-1.2-1.5-1.5
Progressive ratio test 1 inactive lever presses3.33.54.9-1.32.2-2.2-1.82.2-2.20.4-1.2-2.1-2.1
Progressive ratio test 2 active lever presses1.41.52.2-0.41.5-1.5-1.41.4-1.40.4-0.7-1.4-1.4
Progressive ratio test 2 breakpoint1.11.21.7-0.21.3-1.3-1.21.2-1.20.6-0.6-1.3-1.3
Progressive ratio test 2 inactive lever presses4.75.47.2-1.62.7-2.7-2.62.7-2.70.1-1.2-2.7-2.7
Total sessions with >9 infusions0.40.52.80.9-0.20.20.5-0.20.21.70.60.20.2
Short access day 1 total inactive lever presses3.74.15.7-1.52.4-2.4-2.02.4-2.4-0.1-0.8-2.4-2.4
Short access day 10 total inactive lever presses1.82.02.9-1.71.5-1.5-1.21.5-1.5-1.1-1.2-1.5-1.5
Short access day 1 total infusions1.01.11.6-0.01.2-1.2-0.31.2-1.21.1-0.7-1.3-1.3
Short access day 10 total infusions0.10.10.90.4-0.10.1-0.1-0.10.11.00.40.10.1
Short access total infusions0.30.31.90.80.1-0.10.30.1-0.11.40.4-0.1-0.1
Short access day 1 locomotion0.00.00.20.30.1-0.10.00.1-0.10.50.2-0.1-0.1
Short access day 10 total locomotion1.01.12.0-0.71.1-1.1-1.41.1-1.10.5-0.8-1.1-1.1
Short access total locomotion0.30.32.10.8-0.20.20.2-0.10.11.40.80.10.1
Compulsive drug intake0.40.40.6-0.30.8-0.80.00.7-0.7-0.0-0.5-0.8-0.8
One hour access (0.3 mA shock)3.64.25.7-0.82.4-2.4-2.22.3-2.30.7-1.8-2.4-2.4
One hour access (shock baseline)0.91.11.80.21.1-1.1-1.41.1-1.11.0-0.6-1.1-1.1
Number of responses in last shaping day2.32.33.2-0.91.7-1.7-1.21.8-1.81.2-0.7-1.8-1.8
Context. condit. distance diff. score0.60.71.7-1.30.7-0.7-1.10.7-0.70.4-0.4-0.9-0.9
Locomotion velocity, session 10.20.31.41.00.1-0.11.2-0.00.00.40.2-0.0-0.1
Locomotion distance, session 14.05.28.0-1.12.7-2.7-1.12.7-2.7-0.3-2.1-2.8-2.8
Locomotion velocity, session 20.50.52.71.60.1-0.10.9-0.00.01.20.60.10.1
Locomotion distance, session 22.13.04.61.02.1-2.1-0.32.1-2.11.6-0.4-2.1-2.1
Locomotion velocity, session 30.40.41.20.70.6-0.60.20.6-0.61.1-0.3-0.7-0.8
Locomotion distance, session 37.78.411.6-2.13.3-3.3-2.53.2-3.2-0.7-2.7-3.4-3.4
Stereotopy head waving bouts, day 33.74.55.71.9-2.42.42.3-2.42.40.21.72.32.3
Stereotopy head waving duration, day 34.25.16.22.2-2.42.42.5-2.52.50.62.12.32.3
Locomotion velocity, session 73.03.35.4-1.32.3-2.3-1.22.2-2.2-0.6-1.5-1.8-1.7
Locomotion distance, session 71.82.44.1-0.32.0-2.0-0.52.0-2.0-0.3-1.6-1.6-1.5
Stereotopy head waving bouts, day 70.60.72.30.4-0.80.8-0.2-0.80.81.51.20.50.5
Stereotopy head waving duration, day 71.82.14.00.9-1.61.60.8-1.71.71.52.01.21.2
Locomotion velocity, session 80.70.95.80.90.4-0.40.10.3-0.32.41.3-0.3-0.3
Locomotion distance, session 82.13.24.9-0.32.1-2.1-1.32.0-2.01.7-0.6-2.2-2.2
Degree of sensitization distance1.71.73.21.2-1.31.31.3-1.31.3-0.01.01.71.8
Degree of sensitization stereotypy0.50.62.90.1-0.50.5-0.6-0.60.61.71.10.20.2
Condit. Reinf. active minus inactive responses0.00.00.10.10.0-0.00.30.0-0.00.30.3-0.3-0.3
Condit. Reinf. active-inactive response ratio1.21.22.00.7-1.31.31.4-1.31.3-0.11.01.00.9
Condit. Reinf. active responses0.20.31.30.50.1-0.10.50.1-0.11.11.1-0.2-0.2
Condit. Reinf. inactive responses0.91.01.70.21.3-1.3-0.41.2-1.21.20.6-0.9-1.0
Incentive salience index mean0.20.20.50.10.5-0.50.10.5-0.50.40.2-0.7-0.7
Condit. Reinf. lever presses0.40.51.0-0.30.9-0.9-0.40.9-0.90.1-0.1-0.9-1.0
Time in familiar zone, hab. session 10.80.73.9-0.30.6-0.60.70.6-0.6-2.0-1.0-0.5-0.5
Time in novel zone, hab. session 11.21.16.50.7-0.60.6-0.3-0.60.62.51.40.70.7
Total zone transitions, hab. session 11.21.62.5-0.61.6-1.6-0.71.6-1.60.6-0.9-1.5-1.5
Total locomotion distance, hab. session 10.40.51.0-0.40.7-0.7-0.60.7-0.70.9-1.0-0.7-0.7
Locomotion velocity, hab. session 10.10.10.70.00.1-0.1-0.10.1-0.10.9-0.5-0.2-0.1
Time in familiar zone, hab. session 20.70.81.5-0.1-1.01.00.3-1.01.0-1.20.01.01.0
Time in novel zone, hab. session 20.20.21.20.40.4-0.40.20.4-0.41.10.1-0.4-0.4
Total zone transitions, hab. session 21.11.48.01.70.5-0.50.70.5-0.52.80.9-0.5-0.5
Total locomotion distance, hab. session 20.50.64.20.50.5-0.5-0.30.5-0.52.10.2-0.5-0.4
Locomotion velocity, hab. session 20.40.53.90.70.3-0.3-0.10.3-0.32.00.3-0.3-0.2
Novel to familiar place preference ratio0.20.20.4-0.70.4-0.4-0.70.3-0.3-0.3-0.3-0.4-0.4
Novelty place preference0.20.20.6-0.60.4-0.4-0.80.3-0.3-0.0-0.3-0.4-0.4
Time in novel zone, NPP test0.20.20.5-0.60.4-0.4-0.70.4-0.40.2-0.2-0.4-0.4
Total zone transitions, NPP test0.60.81.50.21.0-1.00.11.0-1.00.6-0.7-1.2-1.2
Total locomotion distance, NPP test0.71.03.6-0.61.0-1.0-0.51.0-1.0-0.2-1.9-1.0-1.0
Locomotion velocity, NPP test0.40.62.9-0.30.7-0.7-0.40.7-0.7-0.3-1.7-0.8-0.8
Pavlov. Cond. lever latency0.40.63.2-1.1-0.40.4-0.2-0.40.4-1.8-0.10.50.5
Pavlov. Cond. magazine entry latency1.01.37.92.20.0-0.00.80.0-0.02.80.1-0.0-0.1
Pavlov. Cond. change in total contacts1.31.45.10.71.2-1.2-0.51.1-1.12.3-0.2-1.1-1.2
Pavlov. Cond. index score1.01.37.52.10.2-0.20.80.1-0.12.70.3-0.2-0.2
Pavlov. Cond. latency score0.70.95.81.60.4-0.40.40.4-0.42.40.1-0.4-0.4
Pavlov. Cond. lever contacts0.40.52.30.90.5-0.50.10.5-0.51.5-0.2-0.5-0.6
Pavlov. Cond. magazine entry number1.11.37.9-2.2-0.20.2-0.7-0.10.1-2.8-0.10.20.2
Pavlov. Cond. intertrial magazine entries0.20.20.30.20.5-0.50.40.5-0.5-0.50.4-0.5-0.5
Pavlov. Cond. lever-magazine prob. diff.1.11.48.92.20.2-0.20.70.1-0.13.00.4-0.2-0.2
Pavlov. Cond. response bias0.81.04.82.10.0-0.01.0-0.00.02.20.0-0.0-0.0
Bone: apparent density0.30.52.0-0.20.3-0.30.20.3-0.3-1.4-1.1-0.9-0.9
Bone surface1.73.04.6-1.01.8-1.8-1.31.7-1.7-1.3-2.1-2.1-2.1
Bone volume1.62.74.7-0.91.6-1.6-1.01.6-1.6-1.6-2.2-2.0-2.0
Bone: connectivity density0.20.30.70.20.4-0.4-0.00.4-0.4-0.5-0.7-0.9-0.9
Bone: cortical apparent density0.20.30.90.40.4-0.40.30.4-0.41.00.7-0.4-0.4
Bone: cortical area0.71.12.7-0.91.0-1.0-0.41.1-1.1-1.0-1.6-0.9-1.0
Bone: cortical porosity0.70.75.70.70.1-0.1-0.10.1-0.12.41.10.00.1
Bone: cortical porosity0.70.85.60.80.2-0.2-0.20.2-0.22.41.1-0.1-0.0
Bone: cortical thickness0.10.10.4-0.2-0.10.10.40.0-0.0-0.7-0.60.10.1
Bone: cortical thickness0.50.61.41.2-0.70.71.2-0.60.60.50.70.70.7
Bone: cortical tissue density0.20.31.10.40.3-0.30.30.3-0.31.00.9-0.4-0.4
Bone: elastic displacement0.70.81.30.5-1.11.10.7-1.01.0-0.10.41.11.1
Bone: elastic work0.50.72.8-0.80.5-0.5-0.40.6-0.6-1.7-1.3-0.3-0.3
Bone: endosteal estimation1.32.74.7-1.31.8-1.8-1.21.7-1.7-0.9-2.2-1.8-1.8
Bone: endosteal perimeter1.32.83.9-1.21.8-1.8-1.51.7-1.7-0.7-2.0-1.8-1.9
Bone: final force1.32.13.3-1.81.4-1.4-1.01.4-1.4-1.5-1.8-1.3-1.3
Bone: final moment1.62.64.4-1.91.5-1.5-1.01.6-1.6-1.7-2.1-1.5-1.5
Bone: marrow area1.12.34.3-1.21.6-1.6-1.11.6-1.6-0.9-2.1-1.7-1.7
Bone: maximum diameter0.71.32.4-1.11.0-1.0-0.81.1-1.1-1.3-1.6-1.0-1.0
Bone: maximum force2.34.06.0-2.32.0-2.0-1.42.0-2.0-2.0-2.5-1.9-1.9
Bone: maximum moment2.74.77.4-2.42.1-2.1-1.52.2-2.2-2.1-2.7-2.1-2.1
Bone: minimum diameter2.85.16.3-2.22.3-2.3-2.22.4-2.4-1.3-2.5-2.4-2.3
Bone: periosteal estimation1.42.95.7-1.31.8-1.8-1.01.8-1.8-1.3-2.4-1.8-1.8
Bone: periosteal perimeter0.30.61.8-0.40.7-0.7-0.40.7-0.7-0.6-1.3-0.7-0.7
Bone: post-yield work3.64.86.5-2.42.3-2.3-2.12.2-2.2-0.8-2.0-2.5-2.5
Bone: stiffness1.93.13.9-2.01.9-1.9-1.11.9-1.9-1.5-1.9-1.7-1.7
Bone: tissue strength3.93.87.8-2.81.9-1.9-2.01.9-1.9-1.6-2.0-1.6-1.6
Bone: trabecular number1.72.64.2-1.11.5-1.5-1.01.4-1.4-1.7-1.9-2.0-2.1
Bone: trabecular spacing1.31.73.40.5-1.51.50.6-1.51.50.40.71.81.8
Bone: trabecular thickness0.70.81.8-0.21.0-1.0-0.20.9-0.9-0.8-0.7-1.3-1.3
Bone: trabecular tissue density3.44.77.52.4-2.12.12.7-2.12.11.01.82.52.5
Breakpoint value in progressive ratio session1.41.62.3-1.51.2-1.2-1.41.2-1.2-1.1-1.0-1.3-1.3
Distance traveled before self-admin0.00.00.10.2-0.20.20.2-0.20.2-0.00.10.30.3
Distance traveled after self-admin1.71.84.2-1.51.2-1.2-1.61.2-1.2-0.9-2.0-1.2-1.2
Delta time in closed arm before/after self-admin1.31.33.4-1.80.6-0.6-0.70.6-0.6-1.8-1.6-0.8-0.8
Delta time in open arm before/after self-admin0.80.71.91.4-0.60.60.9-0.60.61.30.80.70.7
Diff in mean of infusions in LGA sessions0.30.31.2-0.1-0.50.5-0.4-0.50.50.81.10.50.5
Extinction: sum of active levers before priming1.11.26.3-1.50.3-0.3-0.70.3-0.3-2.5-1.4-0.3-0.3
Active lever presses in extinction session 61.01.03.9-0.3-0.90.90.7-0.90.9-2.0-0.70.90.9
Delta distance traveled before/after self-admin2.62.85.3-2.21.4-1.4-1.71.4-1.4-1.4-2.3-1.5-1.5
Delta ambulatory time before/after self-admin3.23.46.3-2.21.7-1.7-1.91.7-1.7-1.5-2.5-1.8-1.8
Time in closed arm before self-admin0.50.62.60.5-0.30.30.1-0.30.31.61.50.40.4
Time in closed arm after self-admin0.20.21.3-1.10.2-0.2-0.50.2-0.20.0-0.1-0.2-0.2
Time in open arm before self-admin0.70.83.3-0.60.3-0.3-0.40.3-0.3-1.8-1.8-0.5-0.5
Time in open arm after self-admin0.20.21.00.70.2-0.2-0.10.2-0.2-0.4-1.0-0.2-0.2
Sum of active levers in priming session hrs 5-60.10.10.5-0.60.2-0.2-0.30.2-0.2-0.7-0.4-0.3-0.3
Time to tail flick, vehicle, before self-admin0.20.21.11.00.3-0.30.40.3-0.30.70.6-0.2-0.2
Time to tail flick, vehicle, after self-admin1.21.31.70.9-1.31.30.5-1.31.31.20.81.31.3
Time to tail flick, test, before self-admin2.92.94.5-1.31.9-1.9-1.61.9-1.90.5-0.9-2.1-2.1
Time to tail flick, test, after self-admin0.20.20.30.10.5-0.5-0.30.5-0.50.2-0.4-0.5-0.5
Delta time to tail flick, vehicle, before/after SA0.60.60.9-0.4-1.01.0-0.2-1.01.00.50.00.80.8
Delta time to tail flick, test, before/after SA3.02.73.61.8-1.71.71.8-1.71.70.41.11.91.9
Ambulatory time before self-admin0.10.20.20.4-0.40.40.2-0.40.40.00.40.50.5
Ambulatory time after self-admin4.24.77.5-2.61.9-1.9-2.31.9-1.9-2.0-2.7-2.0-2.0
Total heroin consumption0.50.51.1-1.00.7-0.7-1.00.7-0.7-0.5-0.5-0.8-0.8
Area under the delay curve0.60.72.2-1.50.7-0.7-1.10.7-0.7-0.4-0.3-0.7-0.7
Delay disc. indifference point, 0s delay3.53.85.7-2.42.2-2.2-2.02.1-2.1-0.8-0.9-2.1-2.1
Delay disc. indifference point, 16s delay0.60.61.7-1.30.7-0.7-1.20.7-0.7-0.7-0.2-0.7-0.7
Delay disc. indifference point, 2s delay3.64.14.7-2.12.2-2.2-1.92.1-2.1-1.4-1.7-2.2-2.2
Delay disc. indifference point, 24s delay2.72.64.8-2.21.6-1.6-1.61.6-1.6-1.4-1.4-1.5-1.5
Delay disc. indifference point, 4s delay0.30.30.5-0.20.6-0.6-0.60.6-0.60.70.1-0.6-0.6
Delay disc. indifference point, 8s delay0.20.21.4-1.2-0.10.1-0.5-0.10.10.0-0.20.10.1
Delay discount exponential model param0.50.51.71.3-0.60.61.0-0.60.60.40.40.60.6
Delay discount hyperbolic model param0.70.71.81.3-0.80.81.0-0.80.80.50.50.80.8
Fecal boli incidents, locomotor time 12.52.74.91.5-1.71.71.6-1.61.61.12.21.71.7
Change in fecal boli incidents, locomotor task0.80.81.10.7-0.80.81.1-0.90.9-0.70.31.11.1
Time >=10cm from walls, locomotor time 10.10.10.1-0.0-0.20.20.3-0.30.30.30.20.30.3
Bouts of movement, locomotor time 12.83.14.2-1.81.9-1.9-1.81.9-1.9-0.3-1.2-2.0-2.0
Total resting periods, locomotor time 11.71.92.5-1.41.5-1.5-1.51.4-1.4-0.3-0.9-1.6-1.6
Rest time, locomotor task time 10.91.02.60.7-0.80.81.1-0.90.90.11.61.11.1
Distance moved, locomotor task time 10.50.61.0-0.70.7-0.7-0.80.7-0.70.2-1.0-0.8-0.8
Vertical activity count, locomotor time 11.92.03.3-1.21.5-1.5-1.41.5-1.5-0.6-1.8-1.4-1.4
Time >=10cm from walls, locomotor time 20.70.72.40.8-0.50.50.8-0.50.51.51.20.60.6
Bouts of movement, locomotor time 20.20.20.5-0.20.4-0.4-0.30.5-0.50.7-0.4-0.4-0.4
Total resting periods, locomotor time 20.10.11.10.30.1-0.10.10.1-0.11.0-0.10.00.0
Rest time, locomotor task time 20.70.91.61.1-0.80.81.0-0.80.80.61.31.01.0
Distance moved, locomotor task time 20.80.91.4-0.81.0-1.0-0.81.1-1.10.4-0.9-1.2-1.2
Vertical activity count, locomotor time 22.42.63.2-1.51.7-1.7-1.41.8-1.8-0.7-1.7-1.7-1.7
Weight adjusted by age0.30.30.7-0.80.5-0.5-0.20.6-0.6-0.1-0.8-0.6-0.6
Seeking ratio, delayed vs. immediate footshock3.13.65.3-1.72.0-2.0-1.92.3-2.3-0.8-1.7-1.9-1.9
Locomotion in novel chamber0.91.11.30.8-1.11.11.1-1.11.10.81.11.11.1
Locomotion in novel chamber post-restriction0.20.20.30.4-0.40.40.5-0.40.40.10.60.50.5
Progressive ratio0.10.10.50.6-0.20.20.0-0.10.10.70.20.20.2
Food seeking constrained by brief footshock0.91.12.7-0.91.0-1.0-1.01.0-1.0-0.8-1.7-1.0-1.0
Seeking ratio, punishment vs. effort1.11.31.6-1.31.3-1.3-0.81.2-1.2-0.7-1.1-1.3-1.3
Run reversals in cocaine runway, females1.61.61.9-1.41.3-1.3-1.31.2-1.2-1.0-1.3-1.3-1.3
Run reversals in cocaine runway, males2.92.85.61.0-1.91.92.4-1.71.70.20.91.91.9
Latency to leave start box in cocaine runway1.31.41.9-1.41.2-1.2-1.31.1-1.1-1.2-0.7-1.2-1.2
Latency to leave start box in cocaine runway, F1.71.82.4-1.61.5-1.5-1.01.5-1.5-0.7-0.7-1.5-1.5
Latency to leave start box in cocaine runway, M0.50.50.90.1-0.70.7-0.4-0.90.9-0.60.30.80.8
Cd content in liver0.40.50.8-0.5-0.80.8-0.0-0.90.9-0.00.10.90.9
Co content in liver0.50.61.20.6-0.70.70.6-0.70.7-0.11.01.11.1
Cu content in liver0.91.11.6-1.01.1-1.1-0.71.2-1.2-1.3-1.0-0.9-0.9
Fe content in liver0.10.10.2-0.50.1-0.1-0.10.2-0.20.40.20.20.4
K content in liver0.00.00.20.40.2-0.20.10.2-0.20.30.20.10.0
Mg content in liver0.40.41.61.3-0.10.11.1-0.20.20.40.90.50.5
Mn content in liver3.03.43.82.0-1.91.91.9-1.91.91.41.71.91.8
Na content in liver1.61.72.5-0.91.3-1.3-1.51.3-1.3-0.6-1.3-1.6-1.6
Rb content in liver0.30.40.9-1.00.7-0.7-0.60.7-0.7-0.20.3-0.3-0.4
Se content in liver3.64.48.62.6-1.81.82.5-1.81.82.02.91.71.8
Sr content in liver1.31.22.21.2-0.80.81.1-0.90.91.11.01.41.5
Zn content in liver0.10.10.2-0.20.3-0.30.20.3-0.3-0.50.3-0.0-0.1