Hub : Genes

Hpn

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative TSS ENSRNOT00000079631 0.16 0.09 1.6e-07 0.07 0.06 0.06 0.07 2.0e-08 3.0e-07 8.1e-07 3.2e-08
2 Liver gene expression ENSRNOG00000021097 0.35 0.17 3.7e-04 0.03 0.05 0.05 0.03 1.7e-04 5.9e-06 1.4e-06 2.5e-04
3 Liver isoform ratio ENSRNOT00000079631 0.4 0.11 0.0e+00 0.27 0.26 0.26 0.26 1.2e-29 2.3e-29 6.1e-29 6.9e-29
4 Liver isoform ratio ENSRNOT00000117697 0.36 0.11 0.0e+00 0.23 0.23 0.22 0.23 4.8e-25 9.2e-25 2.5e-24 7.4e-25
5 Liver intron excision ratio chr1:86347133:86348669 0.17 0.07 2.5e-10 0.09 0.09 0.1 0.09 2.2e-10 2.1e-10 9.8e-11 3.0e-10
6 Liver intron excision ratio chr1:86347133:86352169 0.31 0.11 0.0e+00 0.18 0.18 0.18 0.17 3.6e-19 2.4e-19 2.4e-19 7.2e-19
7 Liver intron excision ratio chr1:86348728:86352169 0.15 0.08 2.3e-08 0.08 0.08 0.07 0.08 8.3e-09 2.5e-09 2.5e-08 5.8e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail0.00.10.4-0.20.5-0.10.60.4-0.20.1
BMI without tail0.10.10.6-0.3-0.0-0.20.8-0.2-0.30.2
Body weight1.25.015.42.20.52.4-1.9-3.91.8-1.4
Epididymis fat weight0.51.31.81.20.81.1-1.3-0.91.2-1.1
Glucose0.81.22.1-1.1-1.5-1.11.20.5-1.11.0
Heart weight2.13.04.12.01.91.7-2.0-0.71.8-1.7
Left kidney weight0.82.311.81.0-1.31.1-0.7-3.40.30.3
Right kidney weight1.54.319.41.9-0.61.9-1.3-4.41.0-0.4
Tail length1.03.111.41.6-0.41.5-1.5-3.41.3-1.0
Length with tail3.211.829.23.50.73.5-3.6-5.43.1-2.5
Length without tail4.29.215.33.21.43.3-3.4-3.92.9-2.4
Liver weight, left0.61.01.7-1.0-0.8-1.10.90.3-1.21.3
Liver weight, right0.10.10.4-0.10.00.00.00.4-0.60.6
Parametrial fat weight2.55.08.9-2.0-2.4-1.92.2-0.7-2.73.0
Retroperitoneal fat weight1.24.05.4-2.0-2.0-2.02.11.2-2.32.3
Intraocular pressure0.10.20.6-0.6-0.2-0.50.70.2-0.1-0.1
Extensor digitorum longus weight0.31.12.5-0.8-0.3-1.30.8-1.0-1.21.6
Soleus weight0.10.30.8-0.4-0.4-0.90.30.1-0.60.7
Tibialis anterior weight0.51.83.0-1.2-0.8-1.71.4-0.8-1.41.7
Tibia length3.08.313.63.12.13.0-3.0-3.72.8-2.4
Number of licking bursts0.60.74.0-0.50.7-0.10.52.0-0.0-0.3
Food consumed during 24 hour testing period1.92.33.31.81.61.6-1.3-0.61.6-1.7
Times rat made contact with spout0.40.40.8-0.5-0.5-0.90.6-0.2-0.80.8
Mean time between licks in bursts0.71.02.41.01.50.8-1.0-0.21.0-1.0
Mean num. licks in bursts0.50.73.40.3-0.7-0.3-0.3-1.8-0.30.6
Std. dev. time between licks in bursts1.62.03.31.11.71.3-1.30.71.6-1.8
Water consumed over 24 hours1.21.52.01.41.31.2-1.2-1.31.1-0.9
Indifference point 0 sec0.00.10.20.40.10.30.20.40.1-0.2
Indifference point AUC0.80.91.5-0.8-1.2-0.90.71.1-1.01.0
Indifference point function ln k1.42.03.41.51.91.3-1.3-1.31.2-1.2
Indifference point function log k1.42.03.41.51.91.3-1.3-1.31.2-1.2
Delay discounting total patch changes 0 sec0.10.10.30.50.10.50.00.30.2-0.3
Delay discounting total patch changes 12 sec0.50.71.4-0.6-1.0-0.70.81.2-0.80.7
Delay discounting total patch changes 18 sec0.20.21.0-0.1-0.7-0.10.41.0-0.1-0.1
Delay discounting total patch changes 24 sec0.40.50.80.9-0.30.8-0.6-0.40.8-0.8
Delay discounting total patch changes 6 sec0.20.31.2-0.2-1.1-0.20.40.7-0.50.4
Delay discounting time to switch 0 sec4.06.18.6-2.8-2.4-2.62.91.7-2.52.4
Delay discounting water rate 0 sec0.91.42.71.31.71.3-1.50.30.9-0.9
Delay discounting water rate 12 sec2.23.34.42.01.12.1-2.1-1.11.9-2.0
Delay discounting water rate 18 sec0.20.30.60.70.40.7-0.80.00.3-0.5
Delay discounting water rate 24 sec6.79.211.73.33.43.3-3.1-0.63.1-3.3
Delay discounting water rate 6 sec5.07.39.73.12.43.1-2.9-1.62.7-2.8
Locomotor activity1.21.92.9-1.2-1.4-1.51.20.5-1.71.7
Locomotor testing distance0.61.11.7-0.8-1.1-1.30.80.7-1.21.1
Locomotor testing rearing0.30.41.3-0.4-0.1-0.90.31.1-0.60.3
Light reinforcement 10.40.72.00.51.40.9-0.60.30.8-0.9
Light reinforcement 20.50.63.5-0.01.90.00.00.9-0.20.1
Reaction time number correct0.30.40.80.50.70.9-0.8-0.80.4-0.3
Reaction time mean minus median0.20.20.8-0.4-0.9-0.50.2-0.6-0.10.2
Reaction time mean minus median AUC0.30.41.6-0.2-0.9-0.10.1-1.2-0.20.3
Reaction time num false alarms0.70.91.5-1.1-0.6-0.91.21.2-0.80.7
Reaction time num false alarms AUC1.11.52.4-1.3-0.9-1.21.51.6-1.10.9
Reaction time trials correct on left0.30.40.80.50.70.9-0.8-0.80.4-0.3
Reaction time trials on left0.30.40.80.50.70.9-0.7-0.80.4-0.2
Reaction time mean0.10.10.20.4-0.20.1-0.1-0.40.4-0.4
Reaction time mean AUC0.00.00.20.1-0.5-0.10.1-0.20.1-0.2
Median of all reaction times0.10.10.30.50.00.2-0.0-0.00.4-0.5
Reaction time omissions0.30.40.9-0.7-0.3-0.90.9-0.1-0.70.6
Reaction time false alarm rate1.21.72.7-1.3-1.1-1.41.61.7-1.00.8
Reaction time premature initiation rate0.10.20.40.3-0.00.2-0.40.60.5-0.7
Reaction time premature initiations0.20.30.60.50.30.6-0.80.20.6-0.7
Std. dev. reaction times0.20.20.80.4-0.30.2-0.1-0.90.5-0.5
Reaction time trials completed0.30.40.80.50.70.9-0.7-0.80.4-0.2
Reaction time trials AUC0.10.20.70.20.40.6-0.4-0.80.00.1
Social response proportion1.11.22.60.90.61.1-1.1-1.61.1-0.8
Social responses0.20.20.50.40.40.3-0.7-0.50.4-0.2
Social time5.36.98.72.82.52.5-3.0-2.42.7-2.5
Conditioned locomotion0.40.51.0-0.8-0.1-0.41.01.0-0.70.6
Cocaine response after cond. corrected3.33.74.9-1.9-2.2-1.62.20.6-2.12.2
Cocaine response after cond. not corrected4.55.06.7-2.2-2.6-2.22.40.7-2.42.5
Cocaine response before conditioning0.30.40.90.6-0.20.1-1.0-0.60.7-0.8
Saline control response0.10.10.2-0.2-0.3-0.00.4-0.1-0.40.4
Condit. Reinf. active minus inactive responses1.51.93.11.51.11.4-1.8-1.11.3-1.2
Condit. Reinf. active-inactive response ratio0.10.10.40.30.60.1-0.60.20.3-0.3
Condit. Reinf. active responses2.73.75.42.11.12.2-2.3-1.81.9-1.8
Condit. Reinf. inactive responses2.53.14.51.90.72.1-1.8-1.52.0-1.9
Condit. Reinf. lever presses3.44.69.62.40.72.1-2.4-3.11.9-1.6
Condit. Reinf. lever reinforcers received3.65.17.22.51.42.5-2.7-1.92.3-2.3
Pavlov. Cond. lever latency3.75.16.9-2.6-1.3-2.42.42.6-2.22.0
Pavlov. Cond. magazine entry latency1.01.22.01.40.31.1-1.2-1.21.1-1.0
Pavlov. Cond. change in total contacts5.27.29.83.01.32.7-2.8-3.12.8-2.6
Pavlov. Cond. index score3.34.36.22.51.12.1-2.3-2.32.1-1.9
Pavlov. Cond. latency score3.13.95.82.41.02.0-2.2-2.12.0-1.8
Pavlov. Cond. lever contacts3.75.26.72.61.42.4-2.4-2.52.3-2.1
Pavlov. Cond. magazine entry number3.03.75.0-2.2-1.1-1.82.22.2-1.91.8
Pavlov. Cond. intertrial magazine entries1.31.72.7-1.6-1.2-1.31.41.0-1.21.2
Pavlov. Cond. lever-magazine prob. diff.3.03.95.52.30.91.9-2.2-2.22.0-1.8
Pavlov. Cond. response bias5.06.98.93.01.72.7-2.9-2.62.7-2.5
Conditioned reinforcement - actives0.30.31.40.1-0.60.2-0.31.2-0.1-0.1
Conditioned reinforcement - inactives5.15.77.42.52.42.6-2.70.12.6-2.7
Conditioned locomotion0.60.74.90.00.10.1-0.12.20.0-0.2
Intermittent access intake day 1-15 change1.11.13.01.00.21.1-1.0-1.71.0-0.8
Intermittent access intake escalation1.61.53.21.30.41.3-1.2-1.81.2-1.0
Intermittent access intake escalation 20.20.21.10.1-0.40.1-0.1-1.10.2-0.1
Intermitt. access day 1 inactive lever presses0.70.81.90.80.30.9-0.9-1.40.9-0.6
Intermitt. access day 15 inactive lever presses1.11.21.51.21.21.2-1.2-0.21.2-1.1
Intermitt. access escalation Index0.50.40.70.60.80.5-0.60.10.7-0.8
Intermittent access day 1 total infusions1.11.24.50.60.90.7-0.72.10.8-1.2
Intermittent access day 15 total infusions2.42.74.21.71.61.7-1.60.61.9-2.0
Intermittent access terminal intake (last 3 days)1.92.13.41.31.61.3-1.30.91.6-1.9
Intermittent access total infusions1.61.73.11.01.31.1-1.11.41.4-1.8
Intermittent access day 1 locomotion1.51.62.31.11.11.1-1.21.51.2-1.5
Intermittent access day 15 total locomotion2.62.84.01.91.01.9-1.90.41.9-2.0
Intermittent access total locomotion0.70.83.00.60.40.6-0.61.70.6-0.9
Intermittent access standard deviation2.83.04.61.61.21.8-1.7-1.42.1-2.1
Cocaine induced anxiety0.20.20.50.3-0.70.3-0.2-0.7-0.20.4
Post-drug Anxiety1.21.32.6-1.0-1.6-1.00.90.4-1.31.4
Baseline Anxiety0.70.72.6-0.90.3-0.90.81.6-0.50.3
Lifetime Intake1.01.11.80.81.00.8-0.91.31.0-1.3
Incentive Sensitization - Responses0.70.71.01.00.60.9-1.00.10.9-1.0
Incentive Sensitization - Breakpoint0.60.60.90.90.50.9-0.90.00.8-0.9
Progressive ratio test 1 active lever presses2.32.33.41.80.51.8-1.8-0.11.7-1.8
Progressive ratio test 1 breakpoint1.92.03.11.60.31.7-1.8-0.41.6-1.6
Progressive ratio test 1 inactive lever presses4.75.08.22.22.92.2-2.30.12.4-2.5
Progressive ratio test 2 active lever presses1.61.72.61.40.71.5-1.50.41.4-1.6
Progressive ratio test 2 breakpoint1.21.32.11.30.61.3-1.30.51.3-1.5
Progressive ratio test 2 inactive lever presses6.27.110.32.63.22.7-2.6-0.13.0-3.1
Total sessions with >9 infusions0.20.21.7-0.20.1-0.10.01.3-0.1-0.1
Short access day 1 total inactive lever presses4.44.95.92.32.32.4-2.4-0.02.4-2.4
Short access day 10 total inactive lever presses1.92.13.11.41.71.4-1.4-1.21.5-1.3
Short access day 1 total infusions1.51.63.21.21.81.2-1.30.31.2-1.3
Short access day 10 total infusions0.10.10.8-0.10.0-0.0-0.10.90.2-0.3
Short access total infusions0.20.21.30.10.00.1-0.21.10.0-0.2
Short access day 1 locomotion0.10.10.60.10.80.2-0.20.40.2-0.3
Short access day 10 total locomotion1.11.22.41.00.81.1-1.10.01.3-1.5
Short access total locomotion0.30.31.9-0.20.4-0.10.01.4-0.0-0.2
Compulsive drug intake0.30.30.70.80.20.7-0.60.20.3-0.3
One hour access (0.3 mA shock)4.14.77.22.41.72.4-2.4-0.02.4-2.7
One hour access (shock baseline)1.31.52.81.11.21.2-1.20.41.4-1.7
Number of responses in last shaping day3.03.14.41.62.11.7-1.80.71.8-2.1
Context. condit. distance diff. score0.70.91.81.01.30.5-0.7-0.01.1-1.2
Locomotion velocity, session 10.20.20.50.1-0.3-0.30.00.7-0.60.6
Locomotion distance, session 14.15.37.52.72.42.4-2.7-1.02.3-2.2
Locomotion velocity, session 20.30.31.9-0.0-0.1-0.20.01.4-0.40.3
Locomotion distance, session 22.84.08.32.12.92.0-2.10.91.6-1.8
Locomotion velocity, session 30.50.61.40.91.20.8-0.60.60.5-0.6
Locomotion distance, session 39.210.013.13.63.33.5-3.2-1.33.3-3.2
Stereotopy head waving bouts, day 33.84.66.2-2.3-2.0-2.12.40.8-2.52.5
Stereotopy head waving duration, day 34.25.16.9-2.3-1.8-2.62.50.9-2.62.6
Locomotion velocity, session 72.73.04.71.91.71.5-2.2-0.71.9-1.8
Locomotion distance, session 71.51.93.71.61.21.1-1.9-0.81.4-1.3
Stereotopy head waving bouts, day 70.50.62.6-0.60.3-0.50.81.6-0.2-0.0
Stereotopy head waving duration, day 71.41.73.8-1.3-0.1-1.41.61.9-1.20.9
Locomotion velocity, session 80.81.04.90.31.1-0.1-0.32.20.3-0.6
Locomotion distance, session 83.04.58.72.33.01.7-2.10.72.1-2.4
Degree of sensitization distance2.92.95.0-1.9-2.2-2.11.30.3-1.61.6
Degree of sensitization stereotypy0.50.63.1-0.30.7-0.30.51.80.1-0.4
Condit. Reinf. active minus inactive responses0.10.10.60.30.80.3-0.00.4-0.00.0
Condit. Reinf. active-inactive response ratio1.01.12.1-0.9-0.5-0.91.30.2-1.31.4
Condit. Reinf. active responses0.40.52.10.21.10.3-0.11.4-0.1-0.0
Condit. Reinf. inactive responses1.21.52.51.01.60.8-1.31.61.0-1.1
Incentive salience index mean0.30.41.30.71.20.5-0.50.50.3-0.3
Condit. Reinf. lever presses0.50.71.41.01.20.6-0.90.60.7-0.7
Time in familiar zone, hab. session 10.70.63.40.6-0.10.2-0.6-1.8-0.10.5
Time in novel zone, hab. session 10.90.84.5-0.70.4-0.40.62.1-0.0-0.4
Total zone transitions, hab. session 11.42.03.51.41.91.3-1.60.31.4-1.5
Total locomotion distance, hab. session 10.40.61.20.60.90.7-0.70.30.9-1.1
Locomotion velocity, hab. session 10.10.10.30.10.20.2-0.10.50.2-0.4
Time in familiar zone, hab. session 21.51.53.4-0.9-1.9-1.31.0-1.1-1.01.2
Time in novel zone, hab. session 20.50.51.10.31.00.8-0.41.00.4-0.6
Total zone transitions, hab. session 20.81.13.40.41.80.3-0.51.80.3-0.7
Total locomotion distance, hab. session 20.50.61.20.41.10.6-0.51.00.7-1.0
Locomotion velocity, hab. session 20.30.40.80.20.90.4-0.30.90.4-0.7
Novel to familiar place preference ratio0.10.20.30.30.00.5-0.3-0.30.5-0.5
Novelty place preference0.20.20.30.3-0.00.5-0.4-0.20.6-0.6
Time in novel zone, NPP test0.20.20.40.30.10.5-0.4-0.00.6-0.7
Total zone transitions, NPP test0.71.12.31.11.51.1-1.00.10.8-0.9
Total locomotion distance, NPP test0.71.01.50.90.41.2-1.0-1.21.0-1.0
Locomotion velocity, NPP test0.40.61.30.70.11.0-0.7-1.10.7-0.7
Pavlov. Cond. lever latency0.40.51.5-0.6-0.8-0.30.4-1.2-0.30.6
Pavlov. Cond. magazine entry latency0.20.21.20.10.40.3-0.01.1-0.1-0.4
Pavlov. Cond. change in total contacts1.61.72.41.21.51.3-1.11.21.2-1.6
Pavlov. Cond. index score0.30.41.80.20.60.3-0.11.40.0-0.5
Pavlov. Cond. latency score0.40.51.50.50.80.5-0.41.20.3-0.7
Pavlov. Cond. lever contacts0.40.40.80.60.90.6-0.50.70.5-0.7
Pavlov. Cond. magazine entry number0.30.41.2-0.3-0.8-0.50.2-1.1-0.10.6
Pavlov. Cond. intertrial magazine entries0.10.10.30.50.2-0.0-0.50.2-0.00.2
Pavlov. Cond. lever-magazine prob. diff.0.40.52.30.30.80.4-0.21.50.1-0.6
Pavlov. Cond. response bias0.10.10.70.00.30.30.00.9-0.2-0.2
Bone: apparent density0.30.52.20.7-0.30.6-0.4-1.50.00.2
Bone surface1.52.73.41.91.11.9-1.6-1.81.6-1.4
Bone volume1.42.33.91.70.91.7-1.6-2.01.3-1.1
Bone: connectivity density0.20.30.60.80.10.7-0.5-0.80.3-0.2
Bone: cortical apparent density0.30.31.00.50.90.3-0.31.00.2-0.2
Bone: cortical area0.50.81.70.80.20.9-1.2-1.30.8-0.7
Bone: cortical porosity1.11.26.80.11.0-0.2-0.02.60.4-0.7
Bone: cortical porosity1.31.47.40.21.30.0-0.22.70.5-0.9
Bone: cortical thickness0.10.10.3-0.2-0.5-0.1-0.1-0.6-0.20.3
Bone: cortical thickness0.40.50.8-0.7-0.1-0.90.50.6-0.90.9
Bone: cortical tissue density0.30.41.30.51.00.3-0.31.10.1-0.2
Bone: elastic displacement0.70.81.7-0.9-1.3-0.61.00.3-1.00.9
Bone: elastic work0.30.41.60.3-0.30.3-0.6-1.30.4-0.2
Bone: endosteal estimation1.12.33.01.71.01.4-1.7-1.71.6-1.5
Bone: endosteal perimeter1.32.63.61.70.91.9-1.7-1.51.7-1.6
Bone: final force1.01.72.51.21.11.0-1.5-1.61.4-1.1
Bone: final moment1.22.03.01.41.21.0-1.7-1.71.5-1.2
Bone: marrow area0.91.92.71.60.81.3-1.5-1.71.4-1.3
Bone: maximum diameter0.51.02.21.0-0.01.0-1.1-1.50.9-0.7
Bone: maximum force1.93.24.61.81.21.7-2.1-2.21.9-1.6
Bone: maximum moment2.13.75.11.91.31.7-2.2-2.32.0-1.7
Bone: minimum diameter2.44.46.02.21.12.4-2.4-1.62.3-2.2
Bone: periosteal estimation1.22.43.91.60.81.5-1.8-2.01.5-1.3
Bone: periosteal perimeter0.30.41.20.5-0.30.7-0.8-1.10.6-0.5
Bone: post-yield work3.34.55.82.41.82.1-2.3-1.42.3-2.3
Bone: stiffness1.82.84.01.61.51.6-1.9-2.01.7-1.4
Bone: tissue strength2.92.84.31.71.11.5-1.9-1.52.1-1.9
Bone: trabecular number1.62.54.42.00.91.9-1.4-2.11.3-1.1
Bone: trabecular spacing1.72.13.6-1.6-1.9-1.71.40.9-1.31.2
Bone: trabecular thickness0.70.81.41.21.01.0-1.0-0.80.7-0.5
Bone: trabecular tissue density4.46.29.7-2.7-2.4-3.12.31.5-2.62.6
Breakpoint value in progressive ratio session1.31.41.81.31.01.3-1.3-0.91.3-1.2
Distance traveled before self-admin0.10.10.6-0.3-0.8-0.20.30.1-0.30.3
Distance traveled after self-admin1.41.62.41.20.61.2-1.1-1.61.5-1.4
Delta time in closed arm before/after self-admin0.80.72.20.80.60.8-0.7-1.50.8-0.5
Delta time in open arm before/after self-admin0.50.40.7-0.7-0.5-0.80.70.8-0.70.5
Diff in mean of infusions in LGA sessions0.20.20.8-0.50.2-0.40.40.9-0.0-0.1
Extinction: sum of active levers before priming0.80.84.20.3-1.00.3-0.4-2.10.20.2
Active lever presses in extinction session 61.51.53.9-0.9-2.0-0.90.9-0.9-1.21.4
Delta distance traveled before/after self-admin2.42.63.91.61.11.5-1.5-2.01.8-1.6
Delta ambulatory time before/after self-admin2.93.14.41.81.11.8-1.7-2.11.9-1.8
Time in closed arm before self-admin0.70.85.2-0.5-0.0-0.50.32.3-0.2-0.0
Time in closed arm after self-admin0.40.41.50.11.20.2-0.30.50.7-0.6
Time in open arm before self-admin1.01.05.70.5-0.80.6-0.4-2.40.2-0.0
Time in open arm after self-admin0.30.31.40.3-0.90.2-0.1-1.2-0.0-0.0
Sum of active levers in priming session hrs 5-60.00.00.10.20.10.3-0.1-0.30.2-0.1
Time to tail flick, vehicle, before self-admin0.00.00.10.20.10.2-0.20.2-0.0-0.1
Time to tail flick, vehicle, after self-admin0.91.01.6-1.3-0.7-1.31.01.0-0.80.6
Time to tail flick, test, before self-admin4.14.05.82.12.42.0-2.10.02.1-2.3
Time to tail flick, test, after self-admin0.30.30.50.50.10.5-0.7-0.40.5-0.6
Delta time to tail flick, vehicle, before/after SA0.50.40.6-0.8-0.6-0.80.80.8-0.30.2
Delta time to tail flick, test, before/after SA3.73.34.9-1.9-2.2-1.81.80.5-2.02.0
Ambulatory time before self-admin0.30.31.0-0.5-1.0-0.40.60.4-0.50.4
Ambulatory time after self-admin3.43.85.12.01.02.0-1.8-2.32.2-2.0
Total heroin consumption0.40.50.70.80.60.8-0.7-0.20.8-0.8
Area under the delay curve0.60.71.40.71.20.7-0.80.21.0-0.9
Delay disc. indifference point, 0s delay3.63.95.32.12.32.1-2.0-0.12.1-2.0
Delay disc. indifference point, 16s delay0.50.50.70.70.80.8-0.70.00.9-0.8
Delay disc. indifference point, 2s delay3.43.74.82.21.82.1-2.2-1.32.0-1.8
Delay disc. indifference point, 24s delay2.01.92.71.51.01.6-1.6-0.81.6-1.4
Delay disc. indifference point, 4s delay0.50.51.10.60.90.6-0.61.00.6-0.8
Delay disc. indifference point, 8s delay0.10.10.1-0.10.30.00.00.40.3-0.3
Delay discount exponential model param0.50.51.0-0.6-1.0-0.60.7-0.0-0.90.8
Delay discount hyperbolic model param0.70.71.2-0.8-1.1-0.80.8-0.0-1.00.9
Fecal boli incidents, locomotor time 12.93.26.2-1.7-1.4-1.71.62.5-1.81.7
Change in fecal boli incidents, locomotor task1.11.01.6-1.1-1.1-1.00.9-0.5-1.11.3
Time >=10cm from walls, locomotor time 10.10.10.1-0.30.3-0.30.30.2-0.10.1
Bouts of movement, locomotor time 12.73.04.42.01.22.1-2.0-0.21.8-1.9
Total resting periods, locomotor time 11.61.72.81.60.81.7-1.5-0.11.4-1.4
Rest time, locomotor task time 11.21.31.8-1.1-1.2-1.10.71.3-1.21.3
Distance moved, locomotor task time 10.80.91.60.81.30.8-0.6-1.11.0-1.0
Vertical activity count, locomotor time 11.92.02.51.41.11.4-1.4-1.61.5-1.5
Time >=10cm from walls, locomotor time 20.60.73.3-0.60.3-0.60.51.8-0.50.3
Bouts of movement, locomotor time 20.20.20.50.40.40.5-0.40.20.5-0.7
Total resting periods, locomotor time 20.10.10.3-0.00.10.1-0.10.60.1-0.3
Rest time, locomotor task time 21.01.11.9-1.0-1.0-1.00.81.4-1.11.0
Distance moved, locomotor task time 21.31.53.41.21.81.1-1.0-0.61.3-1.3
Vertical activity count, locomotor time 22.42.63.21.71.61.8-1.5-1.21.8-1.7
Weight adjusted by age0.30.40.50.60.70.6-0.5-0.50.7-0.6
Seeking ratio, delayed vs. immediate footshock3.23.75.71.81.82.0-2.4-0.92.1-2.1
Locomotion in novel chamber0.81.01.5-1.0-0.8-1.01.20.8-1.11.1
Locomotion in novel chamber post-restriction0.10.20.3-0.5-0.1-0.50.40.0-0.50.5
Progressive ratio0.00.10.2-0.2-0.4-0.10.10.4-0.1-0.0
Food seeking constrained by brief footshock0.70.81.21.10.11.0-0.9-1.01.0-0.9
Seeking ratio, punishment vs. effort0.91.11.71.31.01.1-1.2-0.51.1-1.0
Run reversals in cocaine runway, females1.41.41.91.40.71.4-1.1-1.11.3-1.2
Run reversals in cocaine runway, males4.24.06.0-2.0-2.4-2.01.80.8-2.22.3
Latency to leave start box in cocaine runway0.91.01.61.20.71.2-0.9-0.41.1-1.0
Latency to leave start box in cocaine runway, F1.71.92.81.51.71.6-1.4-0.21.4-1.3
Latency to leave start box in cocaine runway, M0.60.61.3-0.7-1.1-0.81.00.0-0.60.6
Cd content in liver0.60.61.1-0.9-1.1-1.00.90.5-0.60.5
Co content in liver0.40.51.1-1.1-0.5-0.70.70.1-0.70.8
Cu content in liver0.70.81.40.80.61.0-1.2-1.10.9-0.7
Fe content in liver0.10.10.5-0.40.1-0.2-0.20.70.1-0.1
K content in liver0.00.00.10.0-0.10.2-0.20.3-0.0-0.0
Mg content in liver0.20.20.5-0.4-0.2-0.20.20.6-0.70.7
Mn content in liver2.83.24.1-1.7-1.5-2.01.91.6-1.91.8
Na content in liver1.61.72.61.61.11.4-1.3-0.61.3-1.4
Rb content in liver0.40.51.70.41.30.6-0.7-0.00.7-0.6
Se content in liver2.93.56.9-1.7-0.5-2.01.82.6-2.01.9
Sr content in liver1.31.22.2-1.5-0.7-1.10.91.3-1.10.9
Zn content in liver0.10.10.30.10.50.3-0.3-0.00.00.1