Hub : Genes

Trank1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000021091 0.55 0.12 0.0e+00 0.49 0.48 0.49 0.49 4.6e-62 1.9e-60 3.4e-61 5.1e-62
2 Brain gene expression ENSRNOG00000021091 0.06 0.05 9.3e-05 0.05 0.04 0.03 0.04 3.4e-05 2.8e-04 7.8e-04 2.4e-04
3 Brain intron excision ratio chr8:111341205:111344393 0.06 0.04 4.0e-06 0.04 0.05 0.04 0.04 7.3e-05 1.1e-05 1.5e-04 1.7e-04
4 LHb intron excision ratio chr8:111315727:111324306 0.3 0.14 3.1e-03 0.07 0.1 0.06 0.06 8.9e-03 1.9e-03 1.9e-02 1.5e-02
5 Liver gene expression ENSRNOG00000021091 0.24 0.09 0.0e+00 0.26 0.27 0.27 0.27 3.8e-29 2.6e-30 9.2e-30 5.8e-30
6 NAcc intron excision ratio chr8:111341205:111343161 0.05 0.03 3.0e-04 0.05 0.04 0.02 0.05 2.2e-04 5.3e-04 8.9e-03 2.0e-04
7 NAcc intron excision ratio chr8:111341205:111344393 0.1 0.06 2.4e-09 0.13 0.11 0.1 0.11 8.9e-10 2.2e-08 4.5e-08 1.2e-08
8 NAcc mRNA stability ENSRNOG00000021091 0.05 0.04 8.9e-04 0.04 0.03 0.03 0.04 7.2e-04 5.8e-03 2.7e-03 1.1e-03
9 PL intron excision ratio chr8:111341205:111343161 0.07 0.06 7.4e-04 0.01 0.03 0.03 0.02 9.5e-02 2.9e-03 2.9e-03 6.3e-03
10 PL intron excision ratio chr8:111341205:111344393 0.05 0.03 2.7e-04 0.03 0.04 0.03 0.03 1.5e-03 2.6e-04 2.6e-03 2.1e-03
11 PL mRNA stability ENSRNOG00000021091 0.05 0.03 2.5e-04 0.05 0.05 0.05 0.05 9.6e-05 1.2e-04 1.6e-04 1.5e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail0.51.63.7-1.2-1.9-1.20.2-1.31.8-1.8-0.8-0.1-1.2-0.9
BMI without tail1.63.44.9-1.7-2.2-2.00.9-1.92.2-2.2-1.90.8-2.0-1.8
Body weight5.824.434.2-5.5-4.9-4.70.0-5.65.9-5.7-5.13.6-5.3-5.2
Epididymis fat weight0.40.81.4-1.0-1.2-0.90.4-0.81.1-1.1-0.71.0-0.9-0.7
Glucose0.40.72.8-0.5-0.3-1.21.7-0.30.5-0.5-0.60.9-0.8-0.6
Heart weight1.72.44.1-1.7-1.3-0.9-1.3-1.91.6-1.6-2.00.5-1.4-1.9
Left kidney weight0.82.48.1-1.1-1.0-2.22.8-0.71.5-1.4-1.11.3-1.5-1.2
Right kidney weight0.41.15.9-0.7-0.5-1.52.4-0.21.1-0.9-0.40.7-0.9-0.5
Tail length5.617.021.6-4.5-3.2-4.10.7-4.54.5-4.5-4.63.9-4.5-4.6
Length with tail7.928.936.4-5.9-4.5-5.30.6-5.95.9-5.8-6.05.1-5.8-6.0
Length without tail5.812.716.4-4.1-3.2-3.3-0.2-4.04.0-4.0-3.73.6-3.8-3.8
Liver weight, left0.30.52.7-0.3-0.3-0.81.70.20.1-0.0-0.21.1-0.4-0.2
Liver weight, right1.32.13.2-1.4-1.4-1.81.5-1.11.6-1.6-1.11.7-1.5-1.2
Parametrial fat weight0.81.62.5-1.1-1.6-1.51.1-1.10.9-1.0-1.41.1-1.4-1.4
Retroperitoneal fat weight0.72.23.6-1.5-1.5-1.71.1-1.21.5-1.5-1.31.9-1.5-1.3
Intraocular pressure1.01.42.1-1.3-1.4-1.00.2-1.21.1-1.1-1.41.2-1.2-1.4
Extensor digitorum longus weight0.20.82.30.70.41.1-1.00.6-0.70.70.8-1.50.90.8
Soleus weight3.39.612.7-3.4-3.1-3.10.4-3.43.6-3.6-3.32.4-3.3-3.3
Tibialis anterior weight0.00.10.4-0.3-0.40.1-0.6-0.30.3-0.3-0.2-0.5-0.1-0.2
Tibia length6.017.023.2-4.3-3.7-4.31.0-4.44.8-4.8-4.13.8-4.5-4.2
Number of licking bursts0.30.41.80.4-0.20.9-1.30.1-0.50.40.3-0.90.60.3
Food consumed during 24 hour testing period1.41.74.4-1.3-2.1-1.1-0.1-1.41.4-1.4-1.30.6-1.3-1.3
Times rat made contact with spout0.30.30.9-0.6-1.0-0.4-0.2-0.60.6-0.6-0.70.2-0.5-0.6
Mean time between licks in bursts1.01.42.51.11.21.3-0.81.0-1.21.11.1-1.61.31.1
Mean num. licks in bursts0.60.81.8-0.8-0.5-1.21.3-0.50.8-0.8-0.71.0-0.9-0.7
Std. dev. time between licks in bursts3.23.86.41.91.02.4-1.81.6-1.91.91.9-2.52.21.9
Water consumed over 24 hours0.20.31.40.1-0.60.6-1.2-0.2-0.00.00.1-0.90.30.1
Indifference point 0 sec1.42.24.4-1.6-1.2-1.61.0-1.31.5-1.5-1.32.1-1.6-1.4
Indifference point AUC0.60.73.0-0.20.9-1.01.70.10.4-0.3-0.21.4-0.5-0.2
Indifference point function ln k0.20.21.20.5-0.60.4-0.40.2-0.20.20.4-1.10.40.4
Indifference point function log k0.20.21.20.5-0.60.4-0.40.2-0.20.20.4-1.10.40.4
Delay discounting total patch changes 0 sec1.52.43.9-1.7-1.4-1.60.6-1.51.6-1.6-1.52.0-1.6-1.5
Delay discounting total patch changes 12 sec0.70.91.9-1.10.1-1.10.6-0.91.0-0.9-1.01.4-1.1-0.9
Delay discounting total patch changes 18 sec2.93.98.3-2.1-1.0-2.10.9-1.91.9-1.7-2.02.9-2.2-2.1
Delay discounting total patch changes 24 sec2.43.03.9-1.9-1.2-1.80.4-1.91.8-1.8-2.01.8-1.9-1.9
Delay discounting total patch changes 6 sec0.40.62.3-0.4-0.1-0.91.5-0.10.5-0.4-0.31.3-0.6-0.4
Delay discounting time to switch 0 sec0.40.61.40.70.11.0-1.00.4-0.90.90.5-1.20.70.6
Delay discounting water rate 0 sec0.30.40.7-0.8-0.2-0.4-0.4-0.70.8-0.7-0.60.7-0.6-0.7
Delay discounting water rate 12 sec0.30.40.8-0.6-0.8-0.6-0.0-0.70.7-0.8-0.90.2-0.6-0.7
Delay discounting water rate 18 sec0.30.53.0-0.3-1.70.1-0.8-0.40.6-0.7-0.2-0.4-0.1-0.1
Delay discounting water rate 24 sec0.71.01.5-1.0-1.2-0.7-0.3-1.01.2-1.2-1.10.8-0.9-1.1
Delay discounting water rate 6 sec0.30.51.1-0.5-0.1-0.80.4-0.60.6-0.6-0.71.1-0.8-0.8
Locomotor activity5.28.211.4-3.1-2.6-2.7-0.0-3.33.1-3.1-3.32.2-3.1-3.4
Locomotor testing distance5.08.412.1-2.9-2.9-2.80.3-3.23.0-3.1-3.52.0-3.1-3.5
Locomotor testing rearing0.40.61.1-0.8-0.9-0.5-0.3-0.90.7-0.7-1.00.3-0.7-1.0
Light reinforcement 10.61.11.8-0.9-1.4-1.10.7-0.91.2-1.2-1.00.8-1.0-1.0
Light reinforcement 20.40.53.30.5-0.4-0.41.80.8-0.00.00.60.10.20.5
Reaction time number correct0.30.41.20.6-0.30.7-0.30.5-0.70.60.4-1.10.70.3
Reaction time mean minus median0.10.10.60.2-0.2-0.40.80.1-0.10.1-0.3-0.2-0.2-0.2
Reaction time mean minus median AUC0.20.31.1-0.3-0.7-0.81.0-0.20.4-0.3-0.60.1-0.5-0.5
Reaction time num false alarms0.20.20.40.50.30.40.30.6-0.60.60.5-0.30.50.4
Reaction time num false alarms AUC0.10.10.40.2-0.10.00.60.4-0.40.30.30.00.20.1
Reaction time trials correct on left0.30.41.20.6-0.30.7-0.30.5-0.70.60.4-1.10.70.3
Reaction time trials on left0.30.41.20.6-0.30.7-0.30.6-0.80.70.4-1.10.70.4
Reaction time mean0.00.00.20.1-0.0-0.10.1-0.1-0.20.1-0.4-0.0-0.1-0.3
Reaction time mean AUC0.00.00.20.1-0.3-0.20.40.0-0.20.2-0.30.0-0.1-0.2
Median of all reaction times0.00.00.20.00.0-0.0-0.1-0.1-0.20.1-0.40.1-0.1-0.4
Reaction time omissions0.40.61.40.70.00.9-0.40.7-1.21.10.4-0.80.80.4
Reaction time false alarm rate0.00.10.20.10.3-0.00.40.3-0.20.10.30.30.10.2
Reaction time premature initiation rate1.41.82.6-1.2-1.3-1.40.5-1.41.3-1.5-1.51.3-1.5-1.6
Reaction time premature initiations0.60.91.6-0.7-1.3-0.90.2-1.00.9-1.1-1.10.5-0.9-1.3
Std. dev. reaction times0.20.21.0-0.2-0.4-0.71.0-0.20.1-0.1-0.60.3-0.5-0.5
Reaction time trials completed0.30.41.20.6-0.30.7-0.30.6-0.80.70.4-1.10.70.4
Reaction time trials AUC0.30.51.50.7-0.20.8-0.30.6-0.80.80.5-1.20.80.4
Social response proportion0.20.20.4-0.3-0.5-0.40.2-0.50.0-0.1-0.50.6-0.5-0.5
Social responses0.40.51.0-0.5-0.6-0.91.0-0.50.6-0.6-0.61.0-0.7-0.6
Social time1.62.16.51.40.21.8-1.80.7-1.51.41.0-2.51.41.0
Conditioned locomotion2.42.84.01.81.61.50.32.0-1.92.01.9-1.01.81.9
Cocaine response after cond. corrected0.40.41.3-0.5-1.00.2-1.2-0.70.4-0.4-0.5-0.9-0.2-0.5
Cocaine response after cond. not corrected1.51.63.6-1.4-1.9-0.7-0.9-1.61.3-1.3-1.3-0.0-1.2-1.4
Cocaine response before conditioning1.11.41.9-1.1-0.9-1.40.6-1.21.2-1.3-1.11.4-1.3-1.1
Saline control response1.62.13.0-1.5-1.1-1.71.3-1.21.4-1.3-1.41.7-1.5-1.4
Condit. Reinf. active minus inactive responses1.72.13.0-1.7-0.4-1.3-0.4-1.71.7-1.7-1.61.3-1.6-1.6
Condit. Reinf. active-inactive response ratio1.31.32.0-1.3-1.3-0.9-0.4-1.41.4-1.4-1.20.3-1.2-1.2
Condit. Reinf. active responses1.31.82.7-1.6-0.2-1.1-0.6-1.61.6-1.6-1.61.0-1.4-1.6
Condit. Reinf. inactive responses0.20.21.60.11.30.3-0.60.1-0.20.2-0.0-0.10.2-0.0
Condit. Reinf. lever presses2.02.74.2-1.9-0.5-1.70.1-1.82.0-2.0-1.81.4-1.8-1.8
Condit. Reinf. lever reinforcers received1.62.23.2-1.7-0.4-1.3-0.5-1.81.7-1.8-1.71.1-1.6-1.7
Pavlov. Cond. lever latency0.40.60.90.80.00.80.00.9-0.90.90.8-0.70.90.8
Pavlov. Cond. magazine entry latency0.10.10.80.30.90.1-0.10.2-0.10.10.3-0.30.20.3
Pavlov. Cond. change in total contacts2.12.94.1-1.9-0.6-1.6-0.3-2.02.0-2.0-1.91.4-1.9-1.9
Pavlov. Cond. index score0.10.10.3-0.30.5-0.3-0.3-0.40.5-0.5-0.30.2-0.4-0.3
Pavlov. Cond. latency score0.10.10.2-0.20.5-0.3-0.2-0.40.5-0.5-0.20.1-0.3-0.2
Pavlov. Cond. lever contacts0.91.21.7-1.2-0.4-1.30.5-1.21.3-1.3-1.21.0-1.3-1.1
Pavlov. Cond. magazine entry number0.20.31.3-0.5-1.1-0.40.1-0.50.4-0.4-0.60.5-0.4-0.6
Pavlov. Cond. intertrial magazine entries0.30.30.60.50.40.8-0.50.6-0.80.80.5-0.20.70.5
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.30.4-0.3-0.2-0.40.5-0.5-0.20.0-0.3-0.2
Pavlov. Cond. response bias0.10.10.3-0.30.5-0.40.0-0.40.5-0.5-0.30.2-0.4-0.3
Conditioned reinforcement - actives0.10.10.50.30.40.10.40.3-0.10.10.4-0.70.20.3
Conditioned reinforcement - inactives1.21.44.20.90.41.5-1.60.7-0.90.71.1-2.11.21.0
Conditioned locomotion0.30.42.00.50.3-0.11.40.8-0.30.40.6-0.50.40.5
Intermittent access intake day 1-15 change1.01.03.50.50.61.3-1.90.3-0.60.50.8-1.70.90.6
Intermittent access intake escalation0.70.72.70.40.51.1-1.60.2-0.40.40.6-1.40.70.5
Intermittent access intake escalation 20.60.63.9-0.2-0.00.7-2.0-0.5-0.0-0.0-0.1-1.30.1-0.2
Intermitt. access day 1 inactive lever presses0.00.00.20.0-0.50.00.10.10.2-0.00.0-0.30.10.1
Intermitt. access day 15 inactive lever presses1.01.23.00.90.31.5-1.70.6-0.70.71.0-1.31.20.9
Intermitt. access escalation Index0.30.31.2-0.2-0.3-0.61.10.10.00.2-0.21.0-0.3-0.1
Intermittent access day 1 total infusions0.00.00.1-0.1-0.2-0.20.40.10.3-0.10.10.2-0.00.1
Intermittent access day 15 total infusions0.20.20.60.20.30.5-0.50.20.00.20.5-0.80.40.4
Intermittent access terminal intake (last 3 days)0.00.00.2-0.0-0.10.2-0.10.10.10.10.3-0.50.20.2
Intermittent access total infusions0.10.10.30.20.10.4-0.10.40.00.20.5-0.50.40.5
Intermittent access day 1 locomotion0.10.10.50.40.20.00.70.5-0.30.20.3-0.50.30.2
Intermittent access day 15 total locomotion0.40.41.10.70.20.21.00.9-0.60.60.7-0.60.50.6
Intermittent access total locomotion0.70.81.50.90.50.41.11.2-0.60.81.1-0.70.81.0
Intermittent access standard deviation0.70.84.9-0.40.00.5-2.2-0.90.4-0.4-0.6-1.2-0.1-0.6
Cocaine induced anxiety0.80.91.90.80.31.1-0.80.7-0.90.91.1-1.41.00.9
Post-drug Anxiety0.50.51.30.70.10.8-0.40.6-0.70.70.8-1.10.80.7
Baseline Anxiety0.10.10.20.40.30.30.20.5-0.30.40.3-0.10.40.4
Lifetime Intake0.10.10.20.20.10.20.20.40.10.20.5-0.40.40.4
Incentive Sensitization - Responses1.81.83.01.31.11.6-1.01.2-1.11.31.4-1.71.51.3
Incentive Sensitization - Breakpoint1.71.82.91.31.11.6-1.11.2-1.11.31.4-1.71.51.2
Progressive ratio test 1 active lever presses0.20.21.3-0.1-0.3-0.61.10.10.1-0.1-0.10.4-0.3-0.1
Progressive ratio test 1 breakpoint0.20.21.4-0.0-0.3-0.51.20.20.10.00.10.4-0.20.1
Progressive ratio test 1 inactive lever presses0.60.62.10.70.51.0-1.00.4-0.60.50.5-1.40.80.5
Progressive ratio test 2 active lever presses0.60.61.00.80.70.80.00.9-0.60.80.9-1.00.90.8
Progressive ratio test 2 breakpoint0.50.50.90.70.60.8-0.20.8-0.60.70.9-0.90.80.8
Progressive ratio test 2 inactive lever presses2.12.45.61.41.02.0-1.81.0-1.11.11.6-2.41.61.5
Total sessions with >9 infusions0.30.31.1-0.1-0.90.6-1.0-0.10.5-0.3-0.1-0.90.3-0.1
Short access day 1 total inactive lever presses2.22.44.01.50.91.7-0.71.6-1.31.32.0-1.91.81.8
Short access day 10 total inactive lever presses0.60.73.20.40.31.0-1.8-0.1-0.10.50.2-1.50.60.3
Short access day 1 total infusions0.60.61.00.80.30.9-0.20.9-0.40.70.9-1.00.90.9
Short access day 10 total infusions0.10.10.3-0.3-0.6-0.30.60.00.6-0.30.00.3-0.20.0
Short access total infusions0.20.20.50.4-0.00.20.70.7-0.10.40.6-0.40.50.6
Short access day 1 locomotion0.20.20.7-0.1-0.8-0.10.60.20.8-0.70.2-0.20.10.1
Short access day 10 total locomotion0.50.52.5-0.3-0.8-0.91.60.00.6-0.5-0.30.9-0.5-0.3
Short access total locomotion0.40.43.0-0.1-0.6-0.71.70.30.5-0.4-0.00.2-0.2-0.1
Compulsive drug intake0.20.21.60.0-0.1-0.41.30.4-0.10.30.10.7-0.10.2
One hour access (0.3 mA shock)0.10.11.00.1-0.2-0.31.00.3-0.00.20.2-0.10.00.2
One hour access (shock baseline)0.00.10.40.00.30.1-0.3-0.0-0.00.00.1-0.60.1-0.0
Number of responses in last shaping day0.60.61.50.40.61.1-1.20.5-0.30.40.8-1.00.90.8
Context. condit. distance diff. score0.10.10.6-0.00.80.2-0.6-0.10.0-0.00.0-0.00.0-0.0
Locomotion velocity, session 10.10.10.30.40.4-0.00.50.3-0.30.20.3-0.20.10.2
Locomotion distance, session 11.11.42.8-0.9-0.1-1.71.7-0.81.2-1.3-0.91.2-1.3-1.0
Locomotion velocity, session 20.20.30.90.61.00.30.10.5-0.40.40.6-0.30.50.6
Locomotion distance, session 20.30.53.70.10.4-0.91.90.30.2-0.20.10.5-0.40.0
Locomotion velocity, session 30.40.42.2-0.10.2-1.01.5-0.10.4-0.5-0.10.9-0.6-0.2
Locomotion distance, session 30.90.93.01.01.70.21.11.1-0.70.71.10.30.61.1
Stereotopy head waving bouts, day 30.60.74.2-0.3-0.90.7-2.1-0.60.2-0.2-0.3-1.20.2-0.3
Stereotopy head waving duration, day 30.50.61.6-0.7-1.30.1-1.3-0.80.5-0.5-0.7-0.6-0.3-0.7
Locomotion velocity, session 70.70.82.5-0.6-0.1-1.21.6-0.30.6-0.6-0.51.4-0.9-0.6
Locomotion distance, session 70.50.71.60.71.20.11.31.0-0.70.70.8-0.10.50.8
Stereotopy head waving bouts, day 70.20.21.10.40.3-0.11.00.6-0.40.40.30.40.20.4
Stereotopy head waving duration, day 70.30.30.9-0.3-0.3-0.80.9-0.30.4-0.4-0.41.0-0.6-0.4
Locomotion velocity, session 80.50.61.4-0.40.9-1.00.8-0.50.7-0.8-0.31.2-0.8-0.4
Locomotion distance, session 80.71.14.5-0.40.7-1.52.1-0.30.8-0.9-0.41.2-1.0-0.5
Degree of sensitization distance1.01.02.0-1.2-1.4-0.80.1-1.10.9-0.9-1.30.4-1.0-1.2
Degree of sensitization stereotypy0.40.53.00.20.3-0.61.70.4-0.20.20.11.1-0.20.2
Condit. Reinf. active minus inactive responses0.10.10.3-0.3-0.30.0-0.6-0.40.1-0.1-0.4-0.0-0.2-0.4
Condit. Reinf. active-inactive response ratio0.20.20.8-0.5-0.40.0-0.9-0.60.3-0.3-0.6-0.0-0.3-0.6
Condit. Reinf. active responses0.10.10.10.2-0.10.3-0.20.2-0.30.30.2-0.30.30.2
Condit. Reinf. inactive responses0.60.71.21.00.40.60.51.0-0.90.91.1-0.60.91.0
Incentive salience index mean0.10.10.20.20.10.3-0.10.2-0.30.30.2-0.40.30.2
Condit. Reinf. lever presses1.11.52.11.40.90.90.51.4-1.31.31.4-1.11.21.4
Time in familiar zone, hab. session 11.31.22.30.80.91.5-1.50.8-1.01.10.9-1.11.20.9
Time in novel zone, hab. session 10.40.31.2-0.4-1.1-0.60.5-0.50.5-0.6-0.6-0.1-0.6-0.5
Total zone transitions, hab. session 10.91.33.8-0.8-0.9-1.62.0-0.61.1-1.1-0.80.9-1.1-0.7
Total locomotion distance, hab. session 10.30.41.1-0.5-0.4-0.91.1-0.40.7-0.7-0.60.5-0.7-0.4
Locomotion velocity, hab. session 10.40.61.9-0.5-0.1-1.11.4-0.40.7-0.7-0.61.0-0.8-0.5
Time in familiar zone, hab. session 20.60.72.30.51.31.1-1.50.3-0.60.60.5-0.60.70.5
Time in novel zone, hab. session 20.20.21.6-0.1-1.3-0.40.9-0.00.0-0.0-0.1-0.2-0.2-0.2
Total zone transitions, hab. session 20.20.31.9-0.1-0.2-0.81.4-0.10.5-0.5-0.1-0.0-0.4-0.1
Total locomotion distance, hab. session 20.40.51.2-0.40.0-1.01.1-0.40.7-0.7-0.60.8-0.7-0.4
Locomotion velocity, hab. session 20.30.41.6-0.30.4-0.91.3-0.20.5-0.5-0.40.8-0.6-0.3
Novel to familiar place preference ratio2.02.17.1-1.0-1.0-2.02.7-0.61.0-1.0-1.01.9-1.4-1.0
Novelty place preference2.12.17.6-1.0-1.0-2.02.8-0.51.0-0.9-1.02.0-1.4-0.9
Time in novel zone, NPP test2.12.26.2-1.2-1.3-2.02.5-0.71.1-1.1-1.21.9-1.5-1.1
Total zone transitions, NPP test2.73.87.3-1.6-1.4-2.72.6-1.42.2-2.2-1.61.5-2.1-1.6
Total locomotion distance, NPP test0.91.32.1-1.0-0.8-1.51.1-1.01.4-1.3-1.11.0-1.2-1.0
Locomotion velocity, NPP test1.11.62.8-1.1-0.6-1.71.4-1.01.5-1.4-1.11.4-1.4-1.0
Pavlov. Cond. lever latency4.25.47.3-2.6-2.7-2.10.0-2.62.4-2.5-2.61.7-2.4-2.6
Pavlov. Cond. magazine entry latency5.97.610.83.03.32.7-0.92.8-3.02.92.9-2.32.92.9
Pavlov. Cond. change in total contacts1.41.54.01.22.01.2-0.61.2-1.21.31.2-0.21.21.2
Pavlov. Cond. index score5.67.211.12.93.32.6-0.82.7-2.92.92.8-2.02.82.8
Pavlov. Cond. latency score5.46.911.32.93.42.5-0.52.8-2.82.82.8-1.92.72.8
Pavlov. Cond. lever contacts2.42.94.21.92.01.40.11.9-1.81.81.9-1.11.71.9
Pavlov. Cond. magazine entry number6.48.010.3-3.1-3.2-2.80.7-3.03.1-3.1-3.02.4-3.0-3.0
Pavlov. Cond. intertrial magazine entries0.40.40.6-0.7-0.8-0.60.1-0.70.7-0.7-0.60.4-0.7-0.8
Pavlov. Cond. lever-magazine prob. diff.5.26.59.82.73.12.7-1.22.5-2.72.72.6-2.12.72.6
Pavlov. Cond. response bias6.27.59.03.03.02.8-0.92.8-3.02.92.9-2.52.92.9
Bone: apparent density0.20.31.3-0.20.4-0.71.10.00.2-0.2-0.20.9-0.4-0.2
Bone surface0.10.10.70.30.90.00.30.3-0.20.20.3-0.10.20.3
Bone volume0.10.10.50.10.7-0.20.50.2-0.00.00.20.4-0.10.1
Bone: connectivity density0.30.51.50.50.80.01.20.8-0.70.70.60.10.40.5
Bone: cortical apparent density0.40.52.30.71.50.40.20.7-0.80.80.60.20.60.6
Bone: cortical area0.30.53.00.40.41.0-1.70.1-0.40.40.4-0.50.60.3
Bone: cortical porosity0.40.43.30.1-0.1-0.51.80.5-0.40.40.10.7-0.10.1
Bone: cortical porosity0.40.42.80.3-0.3-0.31.70.7-0.50.50.30.30.10.3
Bone: cortical thickness0.30.53.9-0.40.20.4-2.0-0.70.4-0.4-0.40.1-0.1-0.4
Bone: cortical thickness0.00.00.0-0.1-0.1-0.10.0-0.10.1-0.1-0.10.2-0.1-0.1
Bone: cortical tissue density0.40.62.40.71.60.40.20.8-0.80.80.60.30.60.7
Bone: elastic displacement0.20.21.7-0.2-0.00.3-1.3-0.50.2-0.2-0.3-0.0-0.1-0.3
Bone: elastic work0.60.71.3-0.8-0.3-0.4-1.1-1.10.9-1.0-0.80.8-0.8-0.8
Bone: endosteal estimation0.10.30.6-0.5-0.7-0.60.4-0.50.4-0.4-0.50.7-0.6-0.5
Bone: endosteal perimeter0.91.82.41.50.61.3-0.01.5-1.51.51.5-1.31.51.5
Bone: final force0.71.11.8-1.1-1.0-0.6-1.0-1.31.1-1.1-1.00.9-1.0-1.1
Bone: final moment0.91.52.4-1.3-1.2-0.7-1.1-1.61.3-1.3-1.20.9-1.1-1.3
Bone: marrow area0.20.30.6-0.6-0.8-0.60.5-0.50.5-0.5-0.50.8-0.6-0.6
Bone: maximum diameter0.50.91.40.90.81.2-1.20.6-0.80.80.9-1.01.00.8
Bone: maximum force0.61.11.6-1.1-1.1-0.8-0.6-1.31.1-1.1-1.01.2-1.0-1.1
Bone: maximum moment0.71.31.9-1.2-1.3-0.8-0.7-1.41.2-1.2-1.11.1-1.1-1.2
Bone: minimum diameter0.20.40.60.7-0.10.8-0.40.6-0.70.70.8-0.70.70.7
Bone: periosteal estimation0.00.10.4-0.2-0.20.1-0.7-0.40.2-0.2-0.10.3-0.1-0.2
Bone: periosteal perimeter0.91.51.91.31.01.4-0.61.3-1.31.41.4-1.11.41.3
Bone: post-yield work0.10.10.6-0.2-0.8-0.30.3-0.20.3-0.2-0.10.1-0.2-0.2
Bone: stiffness0.10.20.5-0.5-0.3-0.40.1-0.40.4-0.4-0.40.7-0.5-0.5
Bone: tissue strength2.82.74.2-1.9-1.0-1.1-1.2-2.11.9-1.9-1.81.6-1.6-1.8
Bone: trabecular number0.60.92.30.91.50.21.11.1-0.90.91.0-0.10.70.9
Bone: trabecular spacing1.11.42.6-1.3-1.6-0.6-1.0-1.51.3-1.3-1.30.6-1.0-1.2
Bone: trabecular thickness0.30.31.3-0.10.8-0.71.20.10.2-0.2-0.01.1-0.4-0.0
Bone: trabecular tissue density0.20.30.8-0.4-0.1-0.80.9-0.30.5-0.5-0.50.5-0.6-0.5
Breakpoint value in progressive ratio session0.10.10.50.00.2-0.40.5-0.10.3-0.2-0.40.7-0.3-0.4
Distance traveled before self-admin0.30.32.2-0.3-0.60.5-1.5-0.50.5-0.2-0.0-0.60.0-0.1
Distance traveled after self-admin0.50.61.10.51.00.8-0.80.4-1.00.90.6-1.10.60.5
Delta time in closed arm before/after self-admin0.10.10.30.4-0.20.00.50.4-0.00.30.20.20.20.2
Delta time in open arm before/after self-admin0.30.30.5-0.60.6-0.60.4-0.40.0-0.4-0.50.7-0.6-0.5
Diff in mean of infusions in LGA sessions0.40.42.50.20.10.8-1.6-0.1-0.20.10.0-1.00.40.0
Extinction: sum of active levers before priming0.40.41.3-0.2-0.9-0.71.1-0.10.7-0.5-0.21.0-0.5-0.2
Active lever presses in extinction session 60.80.71.2-0.4-1.1-1.01.1-0.51.0-0.8-0.61.1-0.8-0.7
Delta distance traveled before/after self-admin0.40.41.20.61.10.20.60.7-1.00.60.5-0.30.50.5
Delta ambulatory time before/after self-admin0.20.20.7-0.30.3-0.60.8-0.2-0.40.1-0.60.4-0.5-0.5
Time in closed arm before self-admin1.41.62.6-1.6-1.2-1.1-0.4-1.61.1-1.4-1.30.6-1.4-1.4
Time in closed arm after self-admin0.10.10.5-0.1-0.7-0.1-0.1-0.20.2-0.1-0.2-0.2-0.2-0.2
Time in open arm before self-admin1.11.22.11.40.51.1-0.01.3-1.01.11.0-1.21.31.1
Time in open arm after self-admin0.60.62.90.41.4-0.31.70.8-0.70.50.40.40.20.4
Sum of active levers in priming session hrs 5-60.40.40.6-0.6-0.3-0.80.8-0.40.6-0.6-0.60.5-0.7-0.6
Time to tail flick, vehicle, before self-admin1.91.93.4-1.4-1.8-1.30.2-1.41.7-1.4-1.41.1-1.4-1.4
Time to tail flick, vehicle, after self-admin0.30.41.2-0.90.2-0.1-1.1-0.80.30.0-0.70.1-0.5-0.7
Time to tail flick, test, before self-admin0.40.43.30.3-0.8-0.61.80.5-0.00.1-0.10.3-0.10.0
Time to tail flick, test, after self-admin0.10.10.50.10.20.5-0.70.20.1-0.00.3-0.40.40.4
Delta time to tail flick, vehicle, before/after SA1.11.12.70.61.61.1-1.30.6-1.21.30.7-0.90.90.7
Delta time to tail flick, test, before/after SA0.20.21.1-0.10.60.5-1.0-0.00.2-0.10.5-0.00.30.4
Ambulatory time before self-admin0.30.32.0-0.2-0.30.6-1.4-0.20.20.10.4-0.70.30.3
Ambulatory time after self-admin0.10.20.60.20.60.10.10.2-0.70.60.3-0.40.20.2
Total heroin consumption0.91.02.1-1.0-0.6-0.7-0.7-1.31.0-1.1-1.30.6-1.0-1.5
Area under the delay curve1.92.03.21.51.40.90.91.7-1.51.51.8-0.71.41.8
Delay disc. indifference point, 0s delay0.10.10.3-0.1-0.4-0.10.30.10.4-0.50.40.10.00.3
Delay disc. indifference point, 16s delay1.01.12.01.11.10.60.61.2-1.31.41.1-0.50.91.1
Delay disc. indifference point, 2s delay0.30.30.80.50.60.40.20.6-0.40.30.8-0.30.50.9
Delay disc. indifference point, 24s delay1.01.01.61.01.10.60.51.1-1.31.21.1-0.80.91.1
Delay disc. indifference point, 4s delay1.92.03.21.51.61.20.21.6-1.31.31.7-1.01.51.8
Delay disc. indifference point, 8s delay1.81.83.11.41.20.90.81.7-1.41.61.7-0.71.31.8
Delay discount exponential model param2.22.43.8-1.6-1.6-1.1-0.7-1.81.6-1.6-1.90.9-1.5-1.9
Delay discount hyperbolic model param2.22.33.8-1.6-1.6-1.1-0.7-1.81.6-1.6-1.90.9-1.5-1.9
Fecal boli incidents, locomotor time 10.40.50.7-0.9-0.3-0.5-0.5-0.80.8-0.8-0.60.8-0.7-0.5
Change in fecal boli incidents, locomotor task0.20.20.5-0.2-0.4-0.40.5-0.10.6-0.7-0.30.5-0.3-0.2
Time >=10cm from walls, locomotor time 10.20.20.70.50.20.00.90.6-0.70.80.30.10.30.3
Bouts of movement, locomotor time 10.00.00.20.00.50.0-0.2-0.1-0.30.4-0.1-0.0-0.0-0.1
Total resting periods, locomotor time 10.00.00.2-0.00.3-0.0-0.2-0.1-0.20.4-0.20.0-0.1-0.1
Rest time, locomotor task time 10.30.30.70.50.10.40.40.8-0.40.50.9-0.50.60.9
Distance moved, locomotor task time 11.31.42.2-1.1-1.0-0.8-0.8-1.51.3-1.4-1.40.9-1.2-1.4
Vertical activity count, locomotor time 10.60.61.2-0.6-0.4-0.6-0.2-0.80.8-0.8-1.10.7-0.8-1.1
Time >=10cm from walls, locomotor time 21.61.72.5-1.3-1.1-1.20.2-1.31.6-1.5-1.31.5-1.3-1.3
Bouts of movement, locomotor time 20.20.20.7-0.4-0.50.1-0.8-0.50.5-0.4-0.10.2-0.2-0.1
Total resting periods, locomotor time 20.10.10.5-0.2-0.20.2-0.7-0.20.2-0.10.20.10.10.2
Rest time, locomotor task time 20.00.10.2-0.00.3-0.10.30.1-0.20.30.10.4-0.00.4
Distance moved, locomotor task time 20.60.71.1-0.8-1.0-0.5-0.6-1.01.0-1.0-0.80.2-0.7-1.0
Vertical activity count, locomotor time 20.00.00.10.0-0.4-0.1-0.0-0.10.1-0.0-0.3-0.3-0.1-0.4
Weight adjusted by age0.40.41.4-0.6-0.80.0-1.2-0.80.6-0.5-0.50.1-0.4-0.6
Seeking ratio, delayed vs. immediate footshock1.41.73.11.20.81.00.91.8-1.21.11.6-0.81.41.8
Locomotion in novel chamber0.20.20.70.20.60.6-0.80.2-0.0-0.10.5-0.60.40.5
Locomotion in novel chamber post-restriction0.81.01.7-1.0-0.6-1.20.9-0.91.0-0.8-0.91.3-1.1-0.9
Progressive ratio3.84.45.8-2.3-2.2-2.31.1-2.02.4-2.4-2.02.0-2.2-2.0
Food seeking constrained by brief footshock0.50.61.00.60.30.8-0.20.8-0.50.60.9-1.00.90.9
Seeking ratio, punishment vs. effort5.06.17.72.62.12.8-1.32.5-2.52.62.5-2.72.82.5
Run reversals in cocaine runway, females1.81.72.51.40.71.5-0.81.3-1.31.41.6-1.21.51.5
Run reversals in cocaine runway, males0.30.31.0-0.00.10.1-1.0-0.60.0-0.4-0.9-0.3-0.3-0.8
Latency to leave start box in cocaine runway0.20.20.4-0.30.3-0.3-0.3-0.50.4-0.5-0.60.2-0.4-0.6
Latency to leave start box in cocaine runway, F0.91.02.2-0.8-0.2-0.3-1.5-1.40.9-1.0-1.30.0-0.8-1.3
Latency to leave start box in cocaine runway, M0.40.41.40.60.7-0.01.20.9-0.40.30.90.40.40.7
Cd content in liver2.12.33.4-1.8-1.5-0.9-1.0-1.81.5-1.5-1.81.1-1.5-1.8
Co content in liver0.10.21.3-0.2-0.20.3-1.1-0.40.1-0.1-0.20.2-0.1-0.2
Cu content in liver4.04.95.7-2.4-2.4-2.20.5-2.32.2-2.2-2.32.3-2.4-2.3
Fe content in liver1.51.82.8-1.6-0.5-0.7-1.3-1.61.1-1.1-1.61.7-1.2-1.6
K content in liver0.80.82.2-0.71.0-1.00.5-0.70.9-0.9-0.71.5-0.9-0.7
Mg content in liver0.40.43.10.11.8-0.30.40.00.2-0.20.10.7-0.20.1
Mn content in liver1.01.12.8-0.80.6-1.41.2-0.71.0-1.0-0.71.7-1.1-0.7
Na content in liver0.40.41.6-0.60.6-0.5-0.1-0.50.4-0.4-0.71.3-0.6-0.7
Rb content in liver1.11.43.3-1.3-1.3-0.1-1.8-1.40.8-0.8-1.40.9-0.9-1.4
Se content in liver0.10.21.60.01.3-0.1-0.1-0.00.2-0.20.00.3-0.00.0
Sr content in liver0.10.10.80.1-0.3-0.50.90.00.3-0.30.1-0.1-0.20.1
Zn content in liver4.75.27.4-2.3-2.2-2.40.9-2.32.4-2.4-2.32.7-2.5-2.3