Hub : Genes

Lrrfip2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio ENSRNOT00000112179 0.02 0.02 3.1e-03 0.02 0.01 0 0.01 3.0e-03 1.7e-02 9.2e-02 2.0e-02
2 BLA gene expression ENSRNOG00000021047 0.09 0.06 7.5e-06 0.1 0.1 0.09 0.1 8.2e-06 6.0e-06 1.6e-05 6.6e-06
3 Brain gene expression ENSRNOG00000021047 0.09 0.06 4.7e-10 0.1 0.11 0.1 0.1 5.9e-10 2.8e-10 1.1e-09 7.6e-10
4 Brain intron excision ratio chr8:111091763:111093020 0.39 0.16 4.3e-06 0.05 0.04 0.05 0.06 3.6e-05 1.2e-04 3.4e-05 3.8e-06
5 Brain intron excision ratio chr8:111091763:111110799 0.32 0.14 0.0e+00 0.2 0.21 0.2 0.21 2.2e-18 3.4e-19 5.9e-18 7.6e-19
6 Liver gene expression ENSRNOG00000021047 0.05 0.04 5.6e-06 0.05 0.04 0.04 0.04 7.0e-06 1.7e-05 2.7e-05 1.3e-05
7 Liver isoform ratio ENSRNOT00000097509 0.02 0.01 3.9e-03 0.01 0.02 0.01 0.01 1.4e-02 3.4e-03 1.5e-02 1.9e-02
8 Liver intron excision ratio chr8:111091763:111110799 0.24 0.1 2.2e-16 0.13 0.12 0.13 0.14 4.3e-14 1.0e-13 1.7e-14 6.9e-15
9 Liver intron excision ratio chr8:111093091:111110799 0.06 0.04 4.0e-06 0.04 0.04 0.04 0.04 1.4e-05 3.9e-05 7.9e-05 2.4e-05
10 NAcc gene expression ENSRNOG00000021047 0.12 0.09 7.9e-08 0.12 0.09 0.09 0.11 4.7e-09 3.0e-07 1.8e-07 8.0e-09
11 PL gene expression ENSRNOG00000021047 0.09 0.05 4.0e-09 0.1 0.12 0.11 0.11 3.2e-08 5.1e-09 1.0e-08 1.2e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail1.34.17.3-2.5-1.5-1.1-2.72.3-2.4-1.32.1-2.4-1.9-1.4
BMI without tail2.45.16.3-2.5-2.1-1.9-2.42.5-2.5-2.02.4-2.5-2.1-2.0
Body weight7.431.337.2-5.2-5.6-5.2-5.66.1-5.7-5.55.8-5.7-5.5-5.6
Epididymis fat weight0.61.53.2-1.3-0.9-0.8-1.80.8-1.4-0.81.3-1.7-1.3-0.8
Glucose0.20.30.7-0.4-0.5-0.7-0.20.4-0.8-0.60.4-0.3-0.6-0.6
Heart weight1.92.74.5-1.4-1.9-1.7-1.02.1-1.4-1.81.5-1.4-1.5-1.9
Left kidney weight0.72.03.3-1.4-1.3-1.4-1.41.4-1.7-1.21.4-1.2-1.8-1.3
Right kidney weight0.30.72.0-0.9-0.6-0.7-0.80.7-1.4-0.60.6-0.5-1.3-0.6
Tail length5.115.520.4-3.1-4.5-4.5-3.04.2-3.7-4.53.9-3.4-3.7-4.5
Length with tail7.928.934.9-4.4-5.9-5.9-4.65.7-5.2-5.95.4-4.8-5.3-5.9
Length without tail6.414.015.3-3.2-3.9-3.7-3.73.8-3.7-3.93.9-3.6-3.9-3.9
Liver weight, left0.00.10.2-0.2-0.1-0.30.2-0.5-0.3-0.20.1-0.3-0.4-0.1
Liver weight, right1.22.12.5-1.5-1.4-1.4-1.61.2-1.5-1.41.5-1.5-1.4-1.4
Parametrial fat weight0.91.93.0-1.7-1.3-1.4-1.51.3-1.2-1.31.3-1.3-1.1-1.3
Retroperitoneal fat weight0.82.74.4-1.7-1.4-1.4-2.11.3-1.8-1.41.8-2.0-1.7-1.4
Intraocular pressure0.81.11.7-1.0-1.2-1.3-0.60.7-1.3-1.30.7-1.0-1.2-1.2
Extensor digitorum longus weight0.10.51.30.50.60.81.1-0.40.30.7-0.80.50.50.7
Soleus weight4.112.014.9-3.3-3.5-3.4-2.83.7-3.9-3.43.5-3.4-3.7-3.5
Tibialis anterior weight0.10.31.2-0.4-0.3-0.10.00.6-1.1-0.20.3-0.4-0.7-0.3
Tibia length7.521.225.6-4.3-4.5-4.3-5.04.9-4.3-4.45.1-4.8-4.6-4.4
Number of licking bursts0.10.10.2-0.10.30.50.3-0.20.20.3-0.3-0.00.30.3
Food consumed during 24 hour testing period2.12.64.7-2.2-1.5-1.3-1.41.6-1.7-1.41.6-2.0-1.3-1.5
Times rat made contact with spout0.40.50.8-0.9-0.7-0.6-0.10.6-0.9-0.70.5-0.7-0.7-0.7
Mean time between licks in bursts1.01.41.91.21.11.21.4-0.81.01.1-1.41.41.21.1
Mean num. licks in bursts0.40.50.8-0.6-0.7-0.9-0.40.6-0.8-0.80.6-0.5-0.8-0.8
Std. dev. time between licks in bursts2.22.74.31.01.82.11.4-1.41.61.9-1.61.21.81.8
Water consumed over 24 hours0.10.10.5-0.7-0.10.2-0.30.4-0.40.00.2-0.5-0.2-0.0
Indifference point 0 sec1.01.62.1-1.1-1.3-1.5-1.20.9-1.0-1.41.4-1.4-1.4-1.3
Indifference point AUC0.10.10.70.8-0.0-0.3-0.2-0.10.4-0.10.10.5-0.0-0.0
Indifference point function ln k0.10.20.7-0.80.20.4-0.70.3-0.20.30.3-0.60.00.2
Indifference point function log k0.10.20.7-0.80.20.4-0.70.3-0.20.30.3-0.60.00.2
Delay discounting total patch changes 0 sec1.32.12.7-1.3-1.5-1.6-1.41.2-1.2-1.51.6-1.5-1.6-1.5
Delay discounting total patch changes 12 sec0.30.41.10.2-0.9-1.0-0.30.60.2-0.90.6-0.0-0.4-0.9
Delay discounting total patch changes 18 sec1.72.34.1-0.7-1.8-2.0-1.31.3-0.9-1.91.6-1.3-1.5-1.8
Delay discounting total patch changes 24 sec2.43.03.8-1.3-1.9-1.9-1.61.8-1.3-1.91.8-1.5-1.8-1.9
Delay discounting total patch changes 6 sec0.00.10.30.0-0.2-0.5-0.0-0.10.1-0.30.2-0.1-0.4-0.3
Delay discounting time to switch 0 sec0.20.30.50.10.50.50.7-0.40.30.5-0.60.40.70.5
Delay discounting water rate 0 sec0.20.20.4-0.1-0.6-0.6-0.50.60.1-0.60.5-0.3-0.5-0.6
Delay discounting water rate 12 sec0.40.60.9-0.9-0.8-0.7-0.80.9-0.9-0.70.7-0.7-1.0-0.8
Delay discounting water rate 18 sec1.11.43.7-1.9-0.5-0.1-1.90.9-1.2-0.31.2-1.8-1.1-0.4
Delay discounting water rate 24 sec1.01.32.3-1.2-1.0-0.9-1.50.9-1.2-1.01.2-1.4-1.3-1.0
Delay discounting water rate 6 sec0.30.51.4-0.1-0.6-0.7-1.20.7-0.3-0.60.9-0.5-0.5-0.6
Locomotor activity5.28.210.2-2.7-3.2-3.1-2.53.2-2.4-3.22.9-2.7-2.3-3.2
Locomotor testing distance5.38.810.8-3.0-3.2-3.2-2.83.3-2.5-3.22.9-2.8-2.5-3.2
Locomotor testing rearing0.30.40.7-0.7-0.8-0.8-0.00.7-0.5-0.80.4-0.6-0.5-0.8
Light reinforcement 10.71.42.2-1.4-1.1-1.0-1.51.1-1.0-1.01.3-1.4-0.8-1.1
Light reinforcement 20.10.20.7-0.70.40.3-0.8-0.3-0.30.40.2-0.4-0.30.4
Reaction time number correct0.20.30.7-0.20.50.60.8-0.50.30.6-0.60.00.40.5
Reaction time mean minus median0.00.00.2-0.4-0.1-0.2-0.20.2-0.1-0.10.00.0-0.3-0.2
Reaction time mean minus median AUC0.20.30.8-0.9-0.5-0.6-0.30.4-0.6-0.50.3-0.4-0.8-0.5
Reaction time num false alarms0.40.61.70.70.60.51.3-0.80.50.6-0.90.70.60.6
Reaction time num false alarms AUC0.10.20.90.30.30.20.9-0.60.20.3-0.50.30.30.3
Reaction time trials correct on left0.20.30.7-0.20.50.60.8-0.50.30.6-0.60.00.40.5
Reaction time trials on left0.20.30.8-0.20.60.60.9-0.60.40.6-0.60.10.40.6
Reaction time mean0.00.00.0-0.1-0.1-0.2-0.10.00.1-0.1-0.10.00.1-0.1
Reaction time mean AUC0.00.00.1-0.3-0.0-0.1-0.1-0.1-0.1-0.0-0.1-0.1-0.1-0.0
Median of all reaction times0.00.00.00.0-0.1-0.1-0.1-0.00.2-0.1-0.10.00.2-0.1
Reaction time omissions0.60.82.40.40.70.61.5-1.00.80.6-1.20.80.90.6
Reaction time false alarm rate0.10.10.40.60.20.10.6-0.50.20.2-0.40.50.20.2
Reaction time premature initiation rate1.41.93.0-1.3-1.4-1.5-1.71.4-0.7-1.51.6-1.4-0.8-1.5
Reaction time premature initiations0.71.01.5-1.2-1.0-1.0-1.21.0-0.5-1.01.1-1.2-0.5-1.0
Std. dev. reaction times0.10.10.2-0.4-0.3-0.5-0.10.2-0.4-0.30.0-0.1-0.5-0.4
Reaction time trials completed0.20.30.8-0.20.60.60.9-0.60.40.6-0.60.10.40.6
Reaction time trials AUC0.30.41.1-0.10.70.71.1-0.60.40.7-0.80.20.50.6
Social response proportion0.20.20.3-0.5-0.5-0.6-0.50.2-0.1-0.50.4-0.40.3-0.5
Social responses0.40.51.0-0.7-0.6-0.7-1.00.4-0.7-0.60.8-0.8-0.2-0.6
Social time0.50.71.8-0.10.81.10.5-0.30.90.9-0.80.51.40.9
Conditioned locomotion2.93.54.61.72.01.91.5-2.11.91.9-1.71.62.12.0
Cocaine response after cond. corrected0.40.51.5-1.0-0.7-0.4-0.20.8-1.2-0.60.1-0.4-0.8-0.6
Cocaine response after cond. not corrected2.32.53.8-1.9-1.6-1.3-1.41.8-1.9-1.51.2-1.5-1.6-1.6
Cocaine response before conditioning1.31.63.0-1.1-1.2-1.2-1.71.3-0.6-1.21.7-1.6-0.9-1.1
Saline control response0.91.22.3-0.9-1.3-1.5-0.30.8-1.2-1.40.9-0.8-1.2-1.3
Condit. Reinf. active minus inactive responses1.62.03.4-0.5-1.7-1.6-1.11.9-1.5-1.61.4-0.7-1.5-1.6
Condit. Reinf. active-inactive response ratio2.02.13.0-1.5-1.5-1.3-1.31.7-1.7-1.41.3-1.2-1.6-1.4
Condit. Reinf. active responses1.11.62.8-0.2-1.6-1.5-0.41.7-1.4-1.51.0-0.3-1.4-1.5
Condit. Reinf. inactive responses0.50.62.01.40.20.21.3-0.20.50.2-0.71.20.50.2
Condit. Reinf. lever presses1.82.44.3-0.7-1.9-1.8-1.12.1-1.5-1.81.5-0.8-1.6-1.8
Condit. Reinf. lever reinforcers received1.41.93.3-0.4-1.7-1.6-0.61.8-1.5-1.71.2-0.5-1.5-1.7
Pavlov. Cond. lever latency0.40.51.10.20.90.80.7-1.10.60.8-0.80.40.40.8
Pavlov. Cond. magazine entry latency0.20.20.60.60.20.3-0.10.10.80.3-0.10.50.60.3
Pavlov. Cond. change in total contacts1.92.64.8-0.7-2.0-1.9-1.32.2-1.2-1.91.7-1.0-1.5-1.9
Pavlov. Cond. index score0.10.20.60.2-0.4-0.3-0.50.80.2-0.30.5-0.0-0.0-0.4
Pavlov. Cond. latency score0.10.10.50.2-0.3-0.2-0.50.70.2-0.30.50.00.1-0.3
Pavlov. Cond. lever contacts0.81.11.9-0.6-1.2-1.2-1.01.4-1.0-1.21.1-0.6-0.8-1.2
Pavlov. Cond. magazine entry number0.30.41.1-0.9-0.5-0.6-0.30.2-1.1-0.50.5-0.8-0.8-0.5
Pavlov. Cond. intertrial magazine entries0.40.61.10.70.70.61.0-1.10.50.6-0.90.70.60.7
Pavlov. Cond. lever-magazine prob. diff.0.10.20.70.2-0.4-0.2-0.50.80.2-0.30.5-0.0-0.0-0.3
Pavlov. Cond. response bias0.10.10.50.3-0.4-0.3-0.30.7-0.1-0.30.30.2-0.1-0.4
Conditioned reinforcement - actives0.50.51.50.40.40.31.2-0.21.00.3-0.90.70.90.3
Conditioned reinforcement - inactives0.60.71.30.40.81.00.9-0.41.10.9-0.90.61.10.8
Conditioned locomotion0.50.72.30.30.60.41.5-0.70.80.5-1.20.80.80.5
Intermittent access intake day 1-15 change0.50.51.10.60.50.81.0-0.20.80.6-0.90.80.80.6
Intermittent access intake escalation0.40.40.90.60.40.70.9-0.10.70.5-0.70.70.80.4
Intermittent access intake escalation 20.10.10.50.1-0.3-0.00.70.70.3-0.2-0.20.20.3-0.3
Intermitt. access day 1 inactive lever presses0.00.00.2-0.4-0.00.0-0.10.1-0.00.0-0.0-0.30.0-0.0
Intermitt. access day 15 inactive lever presses0.40.51.10.30.81.10.1-0.60.80.9-0.40.20.90.9
Intermitt. access escalation Index0.20.10.4-0.3-0.0-0.2-0.5-0.2-0.6-0.10.3-0.4-0.6-0.1
Intermittent access day 1 total infusions0.00.00.0-0.20.0-0.0-0.0-0.1-0.00.0-0.0-0.2-0.10.0
Intermittent access day 15 total infusions0.20.20.80.30.30.40.9-0.20.40.3-0.60.40.40.3
Intermittent access terminal intake (last 3 days)0.00.00.3-0.20.10.20.5-0.00.20.1-0.3-0.00.10.1
Intermittent access total infusions0.10.10.30.10.40.50.5-0.30.30.4-0.50.20.30.4
Intermittent access day 1 locomotion0.20.31.00.20.30.21.0-0.40.50.3-0.70.50.50.3
Intermittent access day 15 total locomotion0.40.51.20.10.70.51.1-0.70.70.6-0.90.50.70.6
Intermittent access total locomotion0.91.01.70.51.10.91.3-1.10.91.0-1.20.80.91.0
Intermittent access standard deviation0.20.21.00.1-0.6-0.30.51.00.5-0.50.10.10.5-0.5
Cocaine induced anxiety0.50.61.00.40.70.91.0-0.60.80.8-0.80.50.80.8
Post-drug Anxiety0.30.41.00.20.50.61.0-0.50.60.6-0.70.50.60.5
Baseline Anxiety0.10.10.20.20.40.40.3-0.50.30.4-0.30.30.30.4
Lifetime Intake0.10.10.30.00.40.40.6-0.40.40.4-0.50.10.30.4
Incentive Sensitization - Responses1.71.72.41.11.31.41.6-1.01.21.3-1.51.31.21.3
Incentive Sensitization - Breakpoint1.61.62.21.11.31.41.5-1.01.21.3-1.51.31.21.3
Progressive ratio test 1 active lever presses0.00.00.1-0.3-0.0-0.20.0-0.1-0.0-0.10.0-0.3-0.1-0.1
Progressive ratio test 1 breakpoint0.00.00.2-0.40.1-0.10.0-0.2-0.10.0-0.0-0.4-0.10.0
Progressive ratio test 1 inactive lever presses0.40.51.10.50.50.70.9-0.31.00.6-0.70.51.00.6
Progressive ratio test 2 active lever presses0.80.91.70.80.90.91.3-0.80.90.9-1.10.91.00.9
Progressive ratio test 2 breakpoint0.60.71.40.60.80.81.2-0.70.70.8-1.00.80.70.8
Progressive ratio test 2 inactive lever presses1.72.03.01.11.31.51.7-0.91.51.4-1.61.31.51.3
Total sessions with >9 infusions0.20.21.1-1.0-0.10.2-0.10.3-0.3-0.00.0-0.8-0.3-0.1
Short access day 1 total inactive lever presses2.02.23.20.91.61.81.4-1.41.51.7-1.61.11.31.7
Short access day 10 total inactive lever presses0.10.10.20.30.10.40.50.20.50.2-0.30.40.50.2
Short access day 1 total infusions0.50.50.80.20.80.90.7-0.70.80.9-0.80.30.70.8
Short access day 10 total infusions0.10.10.4-0.6-0.1-0.1-0.20.0-0.4-0.10.1-0.5-0.5-0.1
Short access total infusions0.20.20.4-0.10.60.50.6-0.60.40.5-0.60.00.40.5
Short access day 1 locomotion0.10.10.8-0.90.00.00.2-0.0-0.30.0-0.1-0.6-0.3-0.0
Short access day 10 total locomotion0.20.20.6-0.8-0.2-0.4-0.4-0.1-0.5-0.30.3-0.6-0.4-0.2
Short access total locomotion0.10.10.5-0.7-0.0-0.20.5-0.2-0.2-0.0-0.3-0.3-0.2-0.1
Compulsive drug intake0.00.00.2-0.10.2-0.0-0.0-0.4-0.20.1-0.00.0-0.10.1
One hour access (0.3 mA shock)0.10.10.7-0.10.20.10.8-0.20.30.1-0.50.10.30.1
One hour access (shock baseline)0.20.20.90.30.10.10.90.10.60.0-0.50.40.50.1
Number of responses in last shaping day0.40.40.70.60.60.90.8-0.50.20.7-0.70.50.30.7
Context. condit. distance diff. score0.10.10.50.70.00.10.20.10.50.0-0.10.50.20.0
Locomotion velocity, session 10.10.10.10.30.30.20.3-0.20.00.2-0.20.40.20.3
Locomotion distance, session 10.70.91.4-0.4-1.0-1.1-1.21.2-0.8-1.01.2-0.6-0.9-1.0
Locomotion velocity, session 20.20.30.70.80.60.60.1-0.30.50.6-0.20.50.60.6
Locomotion distance, session 20.00.00.10.10.1-0.1-0.20.1-0.20.00.4-0.1-0.20.0
Locomotion velocity, session 30.20.21.2-0.2-0.2-0.3-1.10.4-0.4-0.20.7-0.3-0.4-0.2
Locomotion distance, session 30.70.81.71.31.11.00.1-0.90.81.0-0.40.90.61.1
Stereotopy head waving bouts, day 30.10.20.5-0.7-0.4-0.10.10.6-0.5-0.30.1-0.5-0.2-0.4
Stereotopy head waving duration, day 30.30.41.0-1.0-0.7-0.60.10.7-0.8-0.70.2-0.6-0.4-0.7
Locomotion velocity, session 70.20.20.5-0.0-0.5-0.7-0.30.2-0.6-0.50.5-0.3-0.7-0.5
Locomotion distance, session 70.70.81.61.20.90.71.3-1.00.50.8-0.91.20.40.8
Stereotopy head waving bouts, day 70.10.20.40.30.40.30.2-0.60.50.4-0.20.10.50.4
Stereotopy head waving duration, day 70.20.20.5-0.4-0.3-0.5-0.70.2-0.2-0.40.7-0.6-0.2-0.4
Locomotion velocity, session 80.30.41.50.5-0.4-0.5-1.20.7-0.3-0.40.9-0.2-0.5-0.4
Locomotion distance, session 80.20.30.70.2-0.5-0.6-0.80.7-0.4-0.50.8-0.2-0.5-0.5
Degree of sensitization distance1.01.01.5-1.1-1.2-1.20.10.9-1.0-1.20.5-0.8-1.1-1.2
Degree of sensitization stereotypy0.10.10.40.30.3-0.0-0.0-0.60.50.20.10.00.30.2
Condit. Reinf. active minus inactive responses0.10.10.2-0.1-0.3-0.30.50.1-0.2-0.3-0.1-0.1-0.2-0.3
Condit. Reinf. active-inactive response ratio0.10.10.3-0.3-0.5-0.50.40.3-0.5-0.50.0-0.2-0.3-0.5
Condit. Reinf. active responses0.00.10.3-0.00.20.20.5-0.30.10.2-0.20.00.00.2
Condit. Reinf. inactive responses0.40.50.90.30.90.90.3-0.90.71.0-0.50.30.51.0
Incentive salience index mean0.10.10.30.20.20.20.5-0.20.10.2-0.30.20.10.2
Condit. Reinf. lever presses1.01.41.90.91.41.31.0-1.21.11.4-1.10.91.21.3
Time in familiar zone, hab. session 11.51.42.21.11.01.11.5-1.11.21.0-1.41.21.21.0
Time in novel zone, hab. session 10.60.61.3-1.1-0.7-0.6-0.60.8-1.0-0.60.6-0.8-0.9-0.7
Total zone transitions, hab. session 10.91.32.1-1.3-0.9-1.0-1.31.1-1.5-0.91.2-1.1-1.2-0.9
Total locomotion distance, hab. session 10.30.40.7-0.7-0.5-0.6-0.60.6-0.8-0.50.6-0.5-0.7-0.5
Locomotion velocity, hab. session 10.20.40.6-0.4-0.5-0.6-0.80.6-0.7-0.50.7-0.5-0.6-0.5
Time in familiar zone, hab. session 20.70.71.81.30.60.71.0-0.51.00.6-0.71.00.90.7
Time in novel zone, hab. session 20.20.21.3-1.1-0.2-0.3-0.20.0-0.5-0.20.1-0.7-0.3-0.3
Total zone transitions, hab. session 20.20.30.5-0.6-0.3-0.3-0.70.7-0.6-0.30.5-0.4-0.6-0.3
Total locomotion distance, hab. session 20.20.30.6-0.3-0.5-0.6-0.80.6-0.3-0.50.7-0.5-0.4-0.5
Locomotion velocity, hab. session 20.10.10.40.1-0.3-0.4-0.60.4-0.1-0.30.6-0.2-0.3-0.3
Novel to familiar place preference ratio0.90.91.5-1.0-0.9-1.2-0.90.4-1.0-1.01.0-1.1-0.9-0.9
Novelty place preference0.80.91.5-1.0-0.8-1.2-0.80.4-1.0-1.01.0-1.0-0.9-0.9
Time in novel zone, NPP test1.11.21.8-1.2-1.0-1.4-0.90.5-1.2-1.11.0-1.2-1.1-1.1
Total zone transitions, NPP test2.84.05.2-2.0-1.8-1.9-2.32.2-2.2-1.82.1-1.7-2.0-1.8
Total locomotion distance, NPP test1.01.41.8-1.2-1.1-1.1-1.31.3-1.2-1.11.3-1.1-1.1-1.1
Locomotion velocity, NPP test1.01.42.1-1.0-1.1-1.2-1.41.3-1.2-1.11.4-1.1-1.1-1.1
Pavlov. Cond. lever latency4.55.77.0-2.5-2.6-2.6-1.42.3-2.5-2.62.0-2.2-2.6-2.6
Pavlov. Cond. magazine entry latency6.58.310.93.02.93.02.3-2.63.32.9-2.62.83.13.0
Pavlov. Cond. change in total contacts2.12.34.72.21.41.41.1-1.51.81.4-1.21.41.61.4
Pavlov. Cond. index score6.58.310.53.22.92.92.2-2.63.22.9-2.62.83.13.0
Pavlov. Cond. latency score6.38.010.63.32.92.92.1-2.63.12.9-2.52.83.02.9
Pavlov. Cond. lever contacts2.63.14.01.91.91.91.0-1.71.81.9-1.41.62.02.0
Pavlov. Cond. magazine entry number7.49.311.8-3.1-3.1-3.1-2.62.9-3.4-3.12.8-2.9-3.4-3.1
Pavlov. Cond. intertrial magazine entries0.40.50.9-0.6-0.7-0.7-0.40.6-0.6-0.70.6-0.6-1.0-0.7
Pavlov. Cond. lever-magazine prob. diff.5.97.39.53.12.72.82.1-2.43.12.7-2.42.73.02.8
Pavlov. Cond. response bias6.58.010.42.72.93.02.0-2.63.23.0-2.62.73.23.0
Bone: apparent density0.00.00.10.2-0.1-0.3-0.3-0.10.2-0.10.3-0.1-0.2-0.1
Bone surface0.10.10.40.60.30.30.1-0.10.40.3-0.10.30.10.3
Bone volume0.00.00.20.50.10.1-0.2-0.00.20.10.20.1-0.10.1
Bone: connectivity density0.30.51.00.80.70.40.6-1.01.00.6-0.80.80.60.6
Bone: cortical apparent density1.01.32.71.60.80.71.1-1.01.60.8-0.81.21.40.8
Bone: cortical area0.10.20.40.50.30.60.3-0.10.60.40.0-0.10.60.4
Bone: cortical porosity0.10.10.80.10.3-0.00.3-0.90.30.2-0.30.10.10.2
Bone: cortical porosity0.20.21.0-0.00.50.10.5-1.00.40.3-0.50.10.20.4
Bone: cortical thickness0.10.20.50.3-0.4-0.1-0.10.70.2-0.30.7-0.50.0-0.3
Bone: cortical thickness0.00.00.1-0.1-0.1-0.10.30.10.1-0.10.2-0.20.0-0.1
Bone: cortical tissue density1.01.32.71.60.80.71.1-1.01.70.8-0.81.21.50.8
Bone: elastic displacement0.10.10.20.0-0.3-0.1-0.30.40.3-0.20.4-0.40.3-0.2
Bone: elastic work0.70.92.1-0.4-0.9-0.7-1.41.3-0.2-0.81.4-1.2-0.4-0.8
Bone: endosteal estimation0.20.40.9-0.7-0.5-0.6-0.60.3-0.9-0.50.7-0.9-0.8-0.5
Bone: endosteal perimeter0.61.32.10.51.41.50.6-1.30.81.4-1.00.61.11.4
Bone: final force0.91.52.9-1.0-1.2-1.0-1.21.4-0.9-1.11.6-1.7-1.0-1.1
Bone: final moment1.32.13.8-1.3-1.4-1.2-1.41.6-1.1-1.31.8-2.0-1.3-1.3
Bone: marrow area0.20.50.9-0.7-0.5-0.6-0.70.3-1.0-0.60.7-0.9-0.9-0.5
Bone: maximum diameter0.30.60.90.80.81.00.5-0.60.70.8-0.60.50.90.8
Bone: maximum force0.91.53.2-1.0-1.1-1.0-1.11.1-1.1-1.11.6-1.8-1.1-1.1
Bone: maximum moment1.11.83.7-1.2-1.2-1.1-1.31.3-1.2-1.21.7-1.9-1.3-1.2
Bone: minimum diameter0.10.20.6-0.10.60.80.1-0.50.30.7-0.2-0.20.60.7
Bone: periosteal estimation0.10.10.5-0.2-0.2-0.1-0.40.3-0.4-0.20.6-0.7-0.3-0.2
Bone: periosteal perimeter0.81.32.00.91.31.40.8-1.21.01.3-0.90.61.31.3
Bone: post-yield work0.20.30.9-0.8-0.3-0.3-0.60.3-0.7-0.30.6-1.0-0.7-0.3
Bone: stiffness0.10.20.4-0.2-0.4-0.4-0.10.2-0.5-0.40.5-0.6-0.5-0.4
Bone: tissue strength2.82.73.6-0.9-1.8-1.6-1.61.9-1.4-1.81.8-1.4-1.7-1.8
Bone: trabecular number0.61.01.61.31.00.80.7-1.01.21.0-0.91.20.81.0
Bone: trabecular spacing1.31.72.2-1.5-1.3-1.2-1.11.4-1.3-1.31.3-1.4-1.1-1.3
Bone: trabecular thickness0.10.10.40.50.0-0.1-0.6-0.00.4-0.00.5-0.10.10.0
Bone: trabecular tissue density0.10.10.30.0-0.4-0.60.00.4-0.5-0.50.20.0-0.4-0.5
Breakpoint value in progressive ratio session0.10.10.20.2-0.1-0.2-0.50.00.4-0.10.3-0.00.3-0.1
Distance traveled before self-admin0.20.30.6-0.7-0.3-0.1-0.50.5-0.5-0.30.4-0.8-0.6-0.3
Distance traveled after self-admin0.50.61.11.00.50.50.8-0.30.90.5-0.71.01.00.5
Delta time in closed arm before/after self-admin0.10.10.2-0.20.30.3-0.2-0.4-0.50.3-0.2-0.0-0.40.3
Delta time in open arm before/after self-admin0.20.20.40.6-0.3-0.50.10.20.7-0.40.30.30.6-0.3
Diff in mean of infusions in LGA sessions0.00.00.10.20.10.30.20.20.10.1-0.30.30.20.1
Extinction: sum of active levers before priming0.30.30.8-0.9-0.2-0.3-0.70.0-0.6-0.30.5-0.8-0.8-0.3
Active lever presses in extinction session 60.80.71.4-1.1-0.6-0.7-0.90.4-1.1-0.70.7-1.0-1.2-0.7
Delta distance traveled before/after self-admin0.80.81.81.20.70.51.0-0.71.00.6-0.81.31.10.6
Delta ambulatory time before/after self-admin0.10.10.30.4-0.3-0.50.30.20.1-0.3-0.00.60.3-0.3
Time in closed arm before self-admin1.51.82.4-1.3-1.5-1.5-0.81.5-1.1-1.51.3-1.2-1.2-1.5
Time in closed arm after self-admin0.20.20.6-0.7-0.3-0.2-0.20.3-0.8-0.20.2-0.4-0.8-0.3
Time in open arm before self-admin0.80.91.50.51.11.20.7-1.00.51.2-1.20.80.51.1
Time in open arm after self-admin0.80.91.91.40.70.30.8-0.91.30.6-0.71.11.30.7
Sum of active levers in priming session hrs 5-60.20.20.4-0.2-0.5-0.7-0.00.4-0.3-0.60.3-0.2-0.3-0.6
Time to tail flick, vehicle, before self-admin2.32.33.2-1.8-1.5-1.4-1.31.4-1.7-1.51.4-1.6-1.6-1.5
Time to tail flick, vehicle, after self-admin0.20.30.60.2-0.6-0.6-0.40.80.2-0.60.6-0.20.2-0.6
Time to tail flick, test, before self-admin0.10.10.5-0.70.0-0.2-0.3-0.3-0.40.00.1-0.5-0.4-0.0
Time to tail flick, test, after self-admin0.10.10.20.10.30.4-0.2-0.10.30.3-0.20.20.20.3
Delta time to tail flick, vehicle, before/after SA1.11.12.51.60.80.90.6-0.61.50.8-0.71.11.40.8
Delta time to tail flick, test, before/after SA0.10.10.20.50.30.4-0.2-0.10.40.3-0.20.30.30.3
Ambulatory time before self-admin0.10.10.3-0.4-0.10.2-0.30.2-0.30.00.2-0.5-0.4-0.0
Ambulatory time after self-admin0.10.10.40.60.20.10.4-0.20.40.2-0.30.60.50.2
Total heroin consumption0.81.01.6-0.6-1.2-1.1-1.11.2-0.6-1.11.0-0.7-0.5-1.1
Area under the delay curve2.12.22.91.41.61.51.3-1.71.41.6-1.51.41.41.6
Delay disc. indifference point, 0s delay0.00.00.2-0.40.10.1-0.4-0.1-0.30.10.0-0.3-0.30.1
Delay disc. indifference point, 16s delay1.11.11.41.01.11.01.2-1.20.91.1-1.01.00.91.1
Delay disc. indifference point, 2s delay0.30.30.40.60.60.50.3-0.60.60.6-0.60.60.60.6
Delay disc. indifference point, 24s delay1.11.11.61.01.00.91.3-1.01.01.0-1.11.11.01.0
Delay disc. indifference point, 4s delay2.42.52.61.61.61.51.4-1.61.61.6-1.51.61.61.6
Delay disc. indifference point, 8s delay1.81.92.61.21.51.41.2-1.61.21.5-1.41.31.21.5
Delay discount exponential model param2.52.73.1-1.6-1.7-1.6-1.51.8-1.5-1.71.6-1.6-1.5-1.7
Delay discount hyperbolic model param2.52.73.2-1.6-1.7-1.6-1.51.8-1.6-1.71.6-1.6-1.6-1.7
Fecal boli incidents, locomotor time 10.40.40.7-0.3-0.7-0.6-0.80.7-0.7-0.70.7-0.4-0.7-0.7
Change in fecal boli incidents, locomotor task0.10.10.4-0.4-0.1-0.2-0.70.0-0.2-0.20.4-0.5-0.2-0.2
Time >=10cm from walls, locomotor time 10.10.10.40.20.50.30.3-0.70.20.4-0.30.20.20.4
Bouts of movement, locomotor time 10.10.10.30.6-0.0-0.10.30.00.3-0.0-0.20.50.3-0.0
Total resting periods, locomotor time 10.00.00.10.3-0.1-0.10.10.10.1-0.1-0.10.30.1-0.1
Rest time, locomotor task time 10.30.30.50.10.70.70.5-0.70.50.7-0.70.30.50.7
Distance moved, locomotor task time 11.51.72.4-1.1-1.3-1.2-1.51.4-1.1-1.31.5-1.4-1.1-1.3
Vertical activity count, locomotor time 10.50.60.9-0.5-0.8-0.8-0.80.8-0.6-0.81.0-0.7-0.6-0.8
Time >=10cm from walls, locomotor time 21.51.61.9-1.0-1.3-1.3-1.31.2-1.4-1.31.4-1.3-1.4-1.3
Bouts of movement, locomotor time 20.20.20.7-0.4-0.3-0.1-0.80.5-0.3-0.20.6-0.6-0.3-0.2
Total resting periods, locomotor time 20.10.10.5-0.2-0.00.2-0.70.2-0.00.00.3-0.4-0.00.0
Rest time, locomotor task time 20.00.10.20.20.20.1-0.3-0.20.40.10.00.10.40.2
Distance moved, locomotor task time 20.80.91.1-1.1-1.0-0.9-0.61.1-1.0-0.90.9-1.0-1.0-1.0
Vertical activity count, locomotor time 20.00.10.1-0.3-0.2-0.20.30.3-0.3-0.20.1-0.2-0.3-0.2
Weight adjusted by age0.50.61.1-0.7-0.6-0.5-1.10.8-0.9-0.60.8-0.8-0.9-0.6
Seeking ratio, delayed vs. immediate footshock1.51.72.70.71.61.51.1-1.60.81.6-1.51.00.71.5
Locomotion in novel chamber0.10.10.30.40.30.40.2-0.20.50.3-0.30.40.50.4
Locomotion in novel chamber post-restriction0.60.71.1-0.9-0.9-1.1-0.90.8-0.4-1.01.0-0.9-0.5-0.9
Progressive ratio3.64.24.8-2.2-2.1-2.2-1.81.9-2.0-2.22.0-2.0-1.9-2.1
Food seeking constrained by brief footshock0.50.61.30.50.80.91.1-0.70.20.8-1.00.70.20.8
Seeking ratio, punishment vs. effort4.65.67.32.22.52.72.5-2.22.02.6-2.52.22.02.5
Run reversals in cocaine runway, females1.31.32.20.81.41.50.6-1.20.91.4-1.10.81.11.4
Run reversals in cocaine runway, males0.20.20.40.5-0.5-0.40.30.60.5-0.40.10.40.5-0.5
Latency to leave start box in cocaine runway0.10.10.30.3-0.4-0.40.00.50.3-0.40.20.40.3-0.4
Latency to leave start box in cocaine runway, F0.60.71.8-0.2-1.1-1.0-0.41.4-0.2-1.10.7-0.1-0.1-1.1
Latency to leave start box in cocaine runway, M0.50.40.80.70.70.60.3-0.90.70.7-0.50.60.70.7
Cd content in liver1.71.82.9-1.1-1.7-1.6-0.51.3-1.4-1.71.0-1.0-1.3-1.7
Co content in liver0.10.10.2-0.1-0.2-0.1-0.20.3-0.3-0.20.4-0.5-0.4-0.2
Cu content in liver4.35.26.3-2.3-2.3-2.3-2.52.0-2.2-2.32.4-2.5-1.8-2.3
Fe content in liver0.81.01.9-0.1-1.3-1.3-0.20.8-1.0-1.40.9-0.7-1.0-1.3
K content in liver0.40.40.90.6-0.7-0.7-0.60.8-0.4-0.71.0-0.3-0.3-0.6
Mg content in liver0.20.31.91.40.10.10.10.30.30.10.10.70.40.1
Mn content in liver0.50.51.10.2-0.8-0.9-1.00.9-0.4-0.81.0-0.4-0.6-0.7
Na content in liver0.20.20.60.8-0.4-0.50.40.00.6-0.50.30.00.6-0.4
Rb content in liver0.60.71.5-0.6-1.1-1.10.00.6-0.9-1.20.5-0.6-0.8-1.2
Se content in liver0.10.11.01.00.00.10.10.20.10.10.00.50.10.1
Sr content in liver0.30.31.0-0.7-0.1-0.1-1.00.6-0.5-0.10.6-0.6-0.5-0.1
Zn content in liver5.76.38.2-2.2-2.3-2.3-2.92.2-2.7-2.32.8-2.9-2.5-2.3