Hub : Genes

Sbsn

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000021015 0.63 0.11 0.0e+00 0.43 0.44 0.44 0.44 3.2e-52 6.3e-54 2.8e-54 7.3e-54
2 Adipose isoform ratio ENSRNOT00000111530 0.04 0.03 1.9e-04 0.03 0.02 0.03 0.03 4.0e-04 2.0e-03 5.5e-04 4.7e-04
3 Adipose intron excision ratio chr1:85993611:86004764 0.17 0.09 9.3e-12 0.09 0.09 0.08 0.08 9.7e-10 6.6e-10 4.3e-09 1.9e-09
4 Adipose intron excision ratio chr1:86001941:86004764 0.11 0.06 3.9e-07 0.05 0.05 0.05 0.06 1.1e-06 2.1e-06 2.4e-06 8.7e-07
5 Adipose mRNA stability ENSRNOG00000021015 0.17 0.07 0.0e+00 0.15 0.15 0.15 0.15 5.3e-16 1.3e-16 4.3e-16 5.3e-16
6 Brain gene expression ENSRNOG00000021015 0.03 0.02 4.5e-04 0.03 0.03 0.04 0.03 5.0e-04 6.9e-04 2.8e-04 6.9e-04
7 Brain isoform ratio ENSRNOT00000028526 0.04 0.03 1.7e-04 0.03 0.02 0.01 0.02 5.0e-04 4.0e-03 1.5e-02 5.4e-03
8 Brain isoform ratio ENSRNOT00000111530 0.05 0.03 5.0e-05 0.04 0.03 0.03 0.04 6.8e-05 3.6e-04 2.2e-03 3.0e-04
9 Brain intron excision ratio chr1:85983801:85989017 0.03 0.02 1.2e-03 0.02 0.02 0.01 0.01 4.1e-03 5.2e-03 2.3e-02 2.5e-02
10 IL isoform ratio ENSRNOT00000028526 0.72 0.15 3.1e-03 0.06 0.07 0.06 0.06 1.8e-02 1.1e-02 1.5e-02 1.2e-02
11 IL isoform ratio ENSRNOT00000111530 0.64 0.19 2.4e-03 0.06 0.08 0.06 0.06 1.7e-02 5.1e-03 1.6e-02 1.3e-02
12 Liver gene expression ENSRNOG00000021015 0.03 0.02 3.5e-04 0.01 0.01 0 0.01 2.7e-02 1.8e-02 1.9e-01 6.2e-02
13 NAcc gene expression ENSRNOG00000021015 0.1 0.05 1.4e-09 0.1 0.13 0.12 0.11 9.4e-08 1.1e-09 3.6e-09 1.2e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail0.10.50.7-0.80.80.80.2-0.7-0.80.5-0.90.80.1-0.4-0.7-0.8
BMI without tail0.10.20.50.4-0.3-0.50.40.30.3-0.30.4-0.30.7-0.50.20.2
Body weight1.87.612.92.3-3.0-1.6-1.52.13.6-2.63.0-3.0-3.13.22.83.2
Epididymis fat weight0.10.10.5-0.1-0.20.3-0.5-0.20.40.10.2-0.2-0.70.6-0.00.2
Glucose0.30.51.11.1-0.8-1.00.90.8-0.2-0.40.8-0.80.10.20.50.4
Heart weight0.40.61.3-1.20.81.0-1.1-1.00.20.6-0.60.8-0.60.2-0.6-0.4
Left kidney weight3.911.217.03.1-3.5-2.3-0.23.13.6-3.33.4-3.5-3.94.13.73.8
Right kidney weight5.014.320.03.5-4.0-2.6-0.73.44.5-3.73.9-4.0-4.24.44.14.4
Tail length2.98.816.03.0-3.4-2.6-1.22.74.0-2.83.6-3.4-1.62.33.13.5
Length with tail4.115.031.23.3-4.2-2.4-2.83.05.6-3.54.2-4.2-3.53.94.04.7
Length without tail2.65.812.41.4-2.2-0.7-2.41.43.5-1.92.1-2.2-3.33.22.32.8
Liver weight, left0.40.62.20.6-0.6-0.91.50.9-0.3-0.70.7-0.6-0.80.90.60.5
Liver weight, right0.20.32.10.5-0.5-0.71.40.5-0.10.10.6-0.5-0.40.60.20.3
Parametrial fat weight3.36.59.12.7-2.6-2.93.02.90.8-2.82.6-2.6-2.12.62.52.3
Retroperitoneal fat weight0.41.27.70.9-0.6-1.02.80.9-1.4-0.50.7-0.6-0.80.90.3-0.0
Intraocular pressure0.40.52.0-0.30.60.4-0.6-0.6-0.40.2-0.70.61.4-1.4-0.6-0.7
Extensor digitorum longus weight0.72.69.11.1-1.2-0.81.31.40.0-2.11.1-1.2-3.02.81.41.2
Soleus weight0.10.20.60.4-0.3-0.20.70.4-0.3-0.50.2-0.3-0.80.70.30.2
Tibialis anterior weight1.03.36.01.8-1.8-1.71.32.00.4-2.21.7-1.8-2.32.41.81.6
Tibia length1.64.48.81.2-2.0-0.8-1.91.13.0-2.12.0-2.0-2.92.81.92.4
Number of licking bursts3.64.35.6-2.12.21.9-0.2-2.1-2.22.4-2.22.21.7-2.1-2.2-2.3
Food consumed during 24 hour testing period0.40.52.5-0.50.40.8-1.6-0.90.50.6-0.50.40.7-0.8-0.6-0.3
Times rat made contact with spout0.70.81.21.0-1.0-1.01.10.8-0.6-1.01.0-1.0-0.60.90.60.5
Mean time between licks in bursts0.30.40.7-0.80.70.7-0.3-0.9-0.00.4-0.70.70.4-0.5-0.8-0.6
Mean num. licks in bursts4.04.86.52.3-2.5-2.20.82.21.5-2.62.5-2.5-2.02.52.22.3
Std. dev. time between licks in bursts2.63.16.0-1.81.71.6-1.4-1.90.02.0-1.71.72.3-2.4-1.8-1.5
Water consumed over 24 hours0.40.51.40.4-0.7-0.1-0.50.20.7-0.70.6-0.7-1.21.10.40.6
Indifference point 0 sec0.20.31.8-0.30.30.1-0.3-0.30.10.5-0.30.31.3-1.2-0.3-0.3
Indifference point AUC0.10.10.80.0-0.2-0.10.90.2-0.50.30.1-0.2-0.00.0-0.0-0.2
Indifference point function ln k0.10.10.40.4-0.3-0.3-0.4-0.00.4-0.70.4-0.3-0.30.40.10.4
Indifference point function log k0.10.10.40.4-0.3-0.3-0.4-0.00.4-0.70.4-0.3-0.30.40.10.4
Delay discounting total patch changes 0 sec0.20.31.5-0.30.20.1-0.5-0.30.20.5-0.30.21.2-1.1-0.3-0.2
Delay discounting total patch changes 12 sec0.10.10.60.2-0.2-0.30.70.20.10.50.2-0.20.8-0.60.1-0.0
Delay discounting total patch changes 18 sec0.40.51.5-0.70.50.5-0.5-0.5-0.31.1-0.50.51.2-1.2-0.5-0.5
Delay discounting total patch changes 24 sec0.30.43.0-0.50.00.6-1.7-0.30.90.4-0.10.00.2-0.30.10.1
Delay discounting total patch changes 6 sec0.10.10.60.0-0.0-0.20.30.10.10.3-0.0-0.00.8-0.60.0-0.0
Delay discounting time to switch 0 sec0.20.31.60.40.2-0.51.30.7-0.5-0.0-0.10.20.8-0.60.4-0.1
Delay discounting water rate 0 sec0.60.91.8-1.10.91.00.2-1.3-1.20.9-1.00.90.1-0.3-1.3-1.1
Delay discounting water rate 12 sec0.20.42.0-0.2-0.00.2-1.4-0.60.50.50.1-0.00.9-0.7-0.5-0.1
Delay discounting water rate 18 sec0.10.20.5-0.20.30.20.1-0.5-0.50.4-0.30.30.5-0.4-0.7-0.5
Delay discounting water rate 24 sec2.33.26.4-2.11.72.2-2.1-2.5-0.71.8-1.71.70.7-1.2-2.2-1.7
Delay discounting water rate 6 sec0.50.84.3-0.90.51.2-2.1-1.20.80.6-0.50.5-0.0-0.2-0.7-0.2
Locomotor activity0.81.35.91.5-1.1-1.62.41.2-0.5-0.71.1-1.10.10.50.60.5
Locomotor testing distance0.40.62.81.1-0.7-1.21.70.7-0.6-0.30.6-0.70.6-0.10.20.1
Locomotor testing rearing0.50.73.10.00.4-0.21.2-0.5-1.70.7-0.50.41.1-0.8-1.0-1.0
Light reinforcement 10.50.91.4-1.01.00.8-0.3-1.1-0.61.2-1.01.01.1-1.1-1.1-0.9
Light reinforcement 21.11.53.3-1.31.41.01.1-1.2-1.80.7-1.41.40.1-0.4-1.5-1.4
Reaction time number correct0.20.21.40.2-0.2-0.00.20.10.0-0.60.2-0.2-1.21.00.20.3
Reaction time mean minus median0.40.61.20.9-0.9-0.6-0.60.81.1-0.60.8-0.9-0.20.30.90.9
Reaction time mean minus median AUC1.11.52.51.2-1.3-1.0-0.71.21.6-1.21.3-1.3-0.70.91.41.4
Reaction time num false alarms0.40.50.9-0.50.70.50.3-0.4-0.90.7-0.80.70.9-1.0-0.6-0.8
Reaction time num false alarms AUC0.50.71.6-0.50.80.40.5-0.4-1.10.7-0.80.81.2-1.3-0.7-1.0
Reaction time trials correct on left0.20.21.40.2-0.2-0.00.20.10.0-0.60.2-0.2-1.21.00.20.3
Reaction time trials on left0.20.31.40.3-0.3-0.10.30.20.1-0.60.3-0.3-1.21.10.20.3
Reaction time mean0.10.20.70.4-0.5-0.4-0.90.20.5-0.10.5-0.50.5-0.30.30.4
Reaction time mean AUC0.20.20.50.5-0.5-0.5-0.60.30.4-0.10.5-0.50.7-0.40.30.3
Median of all reaction times0.10.10.80.1-0.1-0.2-0.7-0.10.10.20.2-0.10.9-0.6-0.1-0.0
Reaction time omissions0.30.41.00.8-0.6-1.00.40.70.2-0.60.7-0.60.6-0.20.50.4
Reaction time false alarm rate0.60.82.6-0.60.80.40.2-0.5-0.90.9-0.80.81.6-1.6-0.7-1.0
Reaction time premature initiation rate1.01.32.7-1.11.11.0-0.9-1.1-0.21.4-1.11.11.6-1.7-1.1-1.0
Reaction time premature initiations0.60.81.2-0.90.91.0-0.8-1.0-0.21.1-0.90.90.8-1.0-0.9-0.8
Std. dev. reaction times0.40.51.80.6-0.7-0.4-1.30.41.1-0.50.7-0.70.2-0.00.60.7
Reaction time trials completed0.20.31.40.3-0.3-0.10.30.20.1-0.60.3-0.3-1.21.10.20.3
Reaction time trials AUC0.30.51.70.6-0.5-0.40.60.40.0-0.90.5-0.5-1.31.30.40.5
Social response proportion0.60.72.20.3-0.40.2-0.90.31.5-1.00.3-0.4-1.41.10.70.8
Social responses0.10.20.70.1-0.00.2-0.20.10.8-0.3-0.1-0.0-0.70.50.30.4
Social time0.70.95.9-0.2-0.20.6-2.4-0.31.6-0.80.2-0.2-1.10.90.30.7
Conditioned locomotion0.70.81.3-0.91.10.80.1-0.7-0.90.6-1.11.10.8-1.0-0.8-1.0
Cocaine response after cond. corrected1.01.22.91.2-1.0-1.41.71.50.2-1.01.0-1.0-0.30.61.20.9
Cocaine response after cond. not corrected2.12.34.61.9-1.6-2.22.12.00.3-1.31.5-1.60.00.61.51.2
Cocaine response before conditioning0.60.81.41.1-1.2-1.1-0.60.71.1-0.31.1-1.20.6-0.10.70.9
Saline control response0.20.20.50.7-0.5-0.70.60.50.0-0.60.5-0.5-0.20.40.40.4
Condit. Reinf. active minus inactive responses0.30.41.10.3-0.6-0.3-0.40.21.0-0.40.7-0.6-0.60.70.50.8
Condit. Reinf. active-inactive response ratio0.00.00.1-0.20.1-0.00.2-0.1-0.40.20.00.1-0.20.2-0.2-0.1
Condit. Reinf. active responses0.60.83.50.4-0.9-0.3-1.40.31.9-0.50.8-0.9-0.60.70.71.1
Condit. Reinf. inactive responses0.60.74.6-0.0-0.30.4-2.1-0.22.00.10.2-0.30.3-0.30.30.6
Condit. Reinf. lever presses2.93.99.31.6-2.1-1.3-1.21.43.1-2.12.1-2.1-1.61.92.02.4
Condit. Reinf. lever reinforcers received0.50.73.30.1-0.60.0-1.7-0.01.8-0.20.6-0.6-0.40.50.50.9
Pavlov. Cond. lever latency1.41.96.2-0.61.20.31.7-0.6-2.51.1-1.21.21.5-1.5-1.2-1.6
Pavlov. Cond. magazine entry latency0.50.62.80.4-0.7-0.3-0.90.41.7-0.50.8-0.7-0.30.40.81.0
Pavlov. Cond. change in total contacts1.72.39.50.4-1.10.0-2.80.43.1-1.21.1-1.1-1.31.21.31.8
Pavlov. Cond. index score1.21.65.80.6-1.1-0.3-1.80.52.4-1.01.1-1.1-1.11.11.11.5
Pavlov. Cond. latency score1.01.35.30.4-1.0-0.2-1.70.42.3-0.81.0-1.0-1.01.01.01.4
Pavlov. Cond. lever contacts1.11.65.50.4-1.0-0.1-1.90.42.3-0.91.0-1.0-1.41.31.01.4
Pavlov. Cond. magazine entry number1.31.64.5-0.71.20.51.4-0.6-2.11.1-1.31.21.3-1.4-1.1-1.5
Pavlov. Cond. intertrial magazine entries0.20.20.9-0.30.60.20.6-0.1-1.00.3-0.60.60.3-0.4-0.3-0.6
Pavlov. Cond. lever-magazine prob. diff.1.41.86.00.7-1.3-0.5-1.60.72.4-1.11.3-1.3-1.11.21.21.6
Pavlov. Cond. response bias1.21.66.00.2-0.90.1-2.30.22.4-0.80.9-0.9-1.41.30.91.4
Conditioned reinforcement - actives0.30.31.7-0.40.30.20.3-0.4-0.51.3-0.20.30.8-0.6-0.5-0.5
Conditioned reinforcement - inactives3.03.46.0-2.41.92.4-2.0-2.30.02.1-1.91.90.8-1.4-1.8-1.4
Conditioned locomotion3.54.27.2-2.32.32.00.2-2.0-2.02.7-2.22.31.2-1.7-2.1-2.2
Intermittent access intake day 1-15 change1.31.32.40.8-1.1-0.4-1.30.81.5-1.21.0-1.1-1.31.21.21.3
Intermittent access intake escalation1.11.12.30.5-0.9-0.1-1.50.51.5-1.00.8-0.9-1.31.21.01.2
Intermittent access intake escalation 21.01.01.61.0-1.1-0.8-0.71.01.3-0.91.1-1.1-0.40.61.21.2
Intermitt. access day 1 inactive lever presses0.80.94.50.4-0.7-0.1-0.70.62.1-0.80.5-0.7-1.10.91.11.2
Intermitt. access day 15 inactive lever presses0.70.81.9-1.31.01.4-1.1-0.90.60.6-1.01.0-0.3-0.2-0.5-0.4
Intermitt. access escalation Index1.11.01.6-1.31.20.9-0.8-1.1-0.70.7-1.01.20.7-0.9-1.0-0.9
Intermittent access day 1 total infusions5.66.39.7-2.62.62.3-0.8-2.7-2.23.1-2.62.62.2-2.6-2.8-2.7
Intermittent access day 15 total infusions3.13.54.9-2.21.92.2-1.9-2.2-0.72.2-1.91.91.2-1.7-1.9-1.7
Intermittent access terminal intake (last 3 days)3.94.35.7-2.32.12.1-1.6-2.4-1.12.4-2.12.11.9-2.2-2.2-2.0
Intermittent access total infusions4.65.17.3-2.32.22.1-1.4-2.5-1.42.7-2.22.22.4-2.7-2.4-2.3
Intermittent access day 1 locomotion5.65.88.3-2.72.52.7-1.1-2.7-1.62.9-2.62.51.7-2.3-2.6-2.5
Intermittent access day 15 total locomotion3.03.25.0-2.11.72.2-1.8-2.2-0.82.1-1.81.71.1-1.6-1.9-1.6
Intermittent access total locomotion3.94.47.3-2.22.12.1-0.6-2.3-1.62.7-2.22.11.8-2.2-2.3-2.2
Intermittent access standard deviation0.90.96.3-0.1-0.30.3-2.5-0.02.00.20.4-0.3-0.10.00.60.9
Cocaine induced anxiety0.70.82.10.4-0.6-0.40.10.81.0-1.00.8-0.6-1.51.31.00.9
Post-drug Anxiety0.10.20.7-0.10.1-0.20.80.50.3-0.50.00.1-0.50.40.40.2
Baseline Anxiety1.51.62.5-1.11.40.90.3-1.0-1.21.5-1.41.41.5-1.6-1.2-1.4
Lifetime Intake2.93.24.9-1.71.71.5-0.8-2.0-1.42.2-1.71.72.0-2.1-2.0-1.9
Incentive Sensitization - Responses0.50.50.9-0.70.60.8-0.5-0.9-0.70.9-0.70.60.3-0.4-0.9-0.7
Incentive Sensitization - Breakpoint0.30.40.7-0.60.50.7-0.6-0.8-0.60.7-0.60.50.1-0.3-0.7-0.6
Progressive ratio test 1 active lever presses1.61.63.7-1.51.11.5-1.9-1.50.11.7-1.01.10.8-1.1-1.2-0.9
Progressive ratio test 1 breakpoint0.90.93.1-1.10.71.2-1.8-1.10.41.3-0.60.70.5-0.7-0.7-0.5
Progressive ratio test 1 inactive lever presses2.32.44.2-2.01.62.0-1.7-2.00.01.9-1.71.60.5-1.1-1.5-1.2
Progressive ratio test 2 active lever presses1.61.73.3-1.41.21.4-1.4-1.6-0.51.8-1.11.21.0-1.2-1.4-1.2
Progressive ratio test 2 breakpoint1.41.53.2-1.31.11.3-1.2-1.5-0.61.8-1.01.11.1-1.3-1.3-1.1
Progressive ratio test 2 inactive lever presses4.34.99.0-3.02.43.0-2.5-2.7-0.12.1-2.52.40.6-1.5-2.1-1.7
Total sessions with >9 infusions0.80.92.1-0.50.60.20.7-0.8-1.31.2-0.70.61.4-1.3-1.1-1.1
Short access day 1 total inactive lever presses3.53.97.8-2.72.22.8-1.9-2.4-0.22.1-2.22.20.1-1.0-1.9-1.6
Short access day 10 total inactive lever presses0.50.52.0-0.70.30.8-1.4-0.31.0-0.2-0.40.3-1.10.70.10.3
Short access day 1 total infusions0.50.51.0-0.80.60.6-0.2-1.0-0.60.9-0.70.60.5-0.5-1.0-0.8
Short access day 10 total infusions0.70.71.1-0.80.90.6-0.3-0.8-0.81.1-0.80.91.0-1.1-0.9-0.9
Short access total infusions0.70.71.5-0.60.60.30.4-0.8-1.21.1-0.60.61.1-1.0-1.0-1.0
Short access day 1 locomotion0.20.20.4-0.60.60.50.3-0.5-0.40.6-0.50.60.2-0.4-0.5-0.5
Short access day 10 total locomotion1.21.32.6-1.10.91.1-1.3-1.20.31.4-0.90.91.5-1.6-1.0-0.8
Short access total locomotion1.41.42.5-1.01.10.80.4-1.1-1.11.6-1.11.11.4-1.5-1.3-1.3
Compulsive drug intake0.00.00.1-0.1-0.1-0.1-0.0-0.00.10.30.3-0.1-0.10.2-0.00.1
One hour access (0.3 mA shock)1.82.14.4-1.41.01.4-2.1-1.80.21.9-1.01.01.8-1.9-1.5-1.0
One hour access (shock baseline)1.61.93.1-1.31.11.4-1.2-1.7-0.51.6-1.31.11.6-1.8-1.5-1.3
Number of responses in last shaping day2.62.74.5-1.91.61.7-1.3-2.0-1.02.1-1.51.61.3-1.5-1.9-1.6
Context. condit. distance diff. score0.60.81.3-1.11.01.0-1.1-1.0-0.40.8-0.91.00.4-0.7-0.9-0.8
Locomotion velocity, session 10.30.41.30.5-0.5-0.71.20.4-0.6-0.20.7-0.5-0.60.80.20.2
Locomotion distance, session 10.20.31.5-0.50.00.6-1.2-0.70.30.3-0.00.0-0.80.6-0.40.0
Locomotion velocity, session 20.40.51.3-0.20.40.10.8-0.5-1.01.1-0.50.40.9-0.7-0.7-0.7
Locomotion distance, session 21.92.74.9-1.71.51.8-0.3-2.2-1.82.1-1.51.50.3-0.7-2.2-1.9
Locomotion velocity, session 30.20.30.8-0.30.30.20.2-0.6-0.80.9-0.10.30.6-0.5-0.7-0.6
Locomotion distance, session 31.11.26.3-1.30.71.5-2.5-1.41.01.0-0.60.7-0.3-0.2-0.7-0.2
Stereotopy head waving bouts, day 31.01.25.41.2-0.8-1.52.31.4-0.3-1.01.1-0.8-0.10.50.90.6
Stereotopy head waving duration, day 30.91.16.51.1-0.7-1.32.61.2-0.7-1.00.8-0.7-0.00.40.60.2
Locomotion velocity, session 70.50.61.7-0.90.51.1-1.3-0.90.30.7-0.30.5-0.90.5-0.5-0.2
Locomotion distance, session 70.10.20.80.1-0.40.2-0.6-0.30.20.00.5-0.4-0.90.8-0.10.2
Stereotopy head waving bouts, day 72.02.34.0-1.41.61.1-0.1-1.4-1.31.7-1.61.61.9-2.0-1.5-1.6
Stereotopy head waving duration, day 71.41.72.8-1.21.50.80.8-0.9-1.71.2-1.51.51.4-1.5-1.3-1.5
Locomotion velocity, session 83.84.56.5-2.22.31.80.1-2.2-2.52.4-2.22.31.6-1.9-2.5-2.5
Locomotion distance, session 82.74.06.7-2.21.92.2-1.4-2.6-1.72.3-2.01.91.1-1.6-2.5-2.2
Degree of sensitization distance0.80.81.51.2-1.0-1.11.21.1-0.3-0.90.9-1.0-0.20.50.70.5
Degree of sensitization stereotypy3.33.65.6-1.82.01.6-0.6-1.8-1.52.1-2.02.02.1-2.4-1.9-2.0
Condit. Reinf. active minus inactive responses0.10.10.2-0.40.30.30.3-0.4-0.40.4-0.30.3-0.1-0.1-0.4-0.4
Condit. Reinf. active-inactive response ratio0.50.51.90.7-0.6-0.81.40.80.0-0.90.6-0.6-0.50.60.60.4
Condit. Reinf. active responses1.62.02.9-1.61.61.40.4-1.5-1.71.6-1.61.60.2-0.6-1.6-1.6
Condit. Reinf. inactive responses3.84.56.7-2.62.52.4-0.6-2.4-2.12.5-2.32.50.4-1.0-2.3-2.3
Incentive salience index mean0.30.40.7-0.80.70.70.1-0.7-0.50.8-0.60.7-0.0-0.2-0.7-0.7
Condit. Reinf. lever presses0.50.61.5-1.10.91.0-0.5-0.9-0.11.2-0.80.90.1-0.4-0.7-0.6
Time in familiar zone, hab. session 14.03.89.11.6-1.9-1.30.71.71.0-2.31.9-1.9-3.03.01.81.8
Time in novel zone, hab. session 14.74.611.0-1.61.91.4-0.3-2.0-1.52.4-1.81.93.3-3.3-2.2-2.3
Total zone transitions, hab. session 10.40.61.3-0.90.70.9-0.7-1.1-0.51.1-0.50.70.1-0.3-1.0-0.8
Total locomotion distance, hab. session 10.30.52.90.2-0.2-0.3-0.6-0.20.60.90.3-0.21.7-1.3-0.2-0.0
Locomotion velocity, hab. session 10.30.42.50.5-0.4-0.7-0.20.10.50.60.5-0.41.6-1.10.00.2
Time in familiar zone, hab. session 22.22.33.91.8-1.7-1.60.31.81.7-2.01.6-1.7-0.30.71.81.6
Time in novel zone, hab. session 20.80.91.9-0.91.00.70.2-1.0-1.21.4-0.81.00.3-0.5-1.1-1.0
Total zone transitions, hab. session 22.53.26.0-1.31.51.20.7-2.0-2.52.0-1.61.51.7-1.8-2.4-2.3
Total locomotion distance, hab. session 21.52.05.3-0.91.00.8-0.4-1.5-0.91.6-1.21.02.3-2.2-1.6-1.5
Locomotion velocity, hab. session 21.11.54.4-0.70.90.7-0.1-1.3-0.91.3-1.00.92.1-2.0-1.5-1.4
Novel to familiar place preference ratio0.10.10.4-0.50.40.4-0.7-0.30.30.1-0.40.40.1-0.2-0.1-0.1
Novelty place preference0.20.20.6-0.50.50.5-0.8-0.40.20.3-0.40.50.4-0.5-0.3-0.3
Time in novel zone, NPP test0.30.30.5-0.70.70.6-0.7-0.6-0.10.5-0.60.70.4-0.6-0.5-0.5
Total zone transitions, NPP test0.10.10.3-0.1-0.00.10.1-0.4-0.50.50.1-0.0-0.30.2-0.5-0.3
Total locomotion distance, NPP test0.81.12.21.3-1.4-1.2-0.50.81.5-0.51.4-1.40.30.20.91.2
Locomotion velocity, NPP test1.01.42.61.4-1.5-1.4-0.41.01.6-0.71.5-1.50.50.11.11.3
Pavlov. Cond. lever latency0.91.23.00.7-0.9-0.4-0.31.00.9-1.60.9-0.9-1.71.51.21.0
Pavlov. Cond. magazine entry latency1.11.57.60.40.0-0.50.8-0.7-1.21.3-0.20.02.8-2.1-1.2-1.0
Pavlov. Cond. change in total contacts2.93.06.0-1.31.41.2-0.5-1.9-1.22.5-1.51.42.4-2.3-2.0-1.8
Pavlov. Cond. index score1.31.77.0-0.20.5-0.00.8-1.0-1.31.6-0.60.52.6-2.1-1.4-1.3
Pavlov. Cond. latency score1.21.55.8-0.40.60.20.5-1.1-1.11.6-0.70.62.4-2.0-1.4-1.2
Pavlov. Cond. lever contacts0.60.83.1-0.40.60.20.1-0.8-0.41.2-0.60.61.7-1.5-0.9-0.7
Pavlov. Cond. magazine entry number1.31.67.20.0-0.30.1-0.71.01.3-1.50.5-0.3-2.72.11.41.3
Pavlov. Cond. intertrial magazine entries0.50.62.2-0.90.70.80.4-0.4-0.90.2-0.50.7-1.51.0-0.4-0.4
Pavlov. Cond. lever-magazine prob. diff.1.72.18.5-0.30.70.10.7-1.2-1.41.8-0.80.72.9-2.4-1.6-1.5
Pavlov. Cond. response bias0.70.84.50.5-0.2-0.71.0-0.3-0.80.90.1-0.22.1-1.5-0.7-0.6
Bone: apparent density1.32.13.31.3-1.5-1.30.41.51.4-1.51.5-1.5-1.61.81.61.7
Bone surface0.50.92.60.5-0.8-0.3-1.20.51.6-0.80.9-0.8-1.11.10.91.2
Bone volume0.91.53.00.8-1.2-0.7-0.80.81.7-1.11.2-1.2-1.51.61.21.5
Bone: connectivity density0.20.30.60.4-0.6-0.50.20.50.8-0.50.6-0.6-0.50.60.60.7
Bone: cortical apparent density1.11.42.9-1.31.31.20.3-1.3-1.71.2-1.31.3-0.0-0.4-1.4-1.4
Bone: cortical area0.91.31.91.2-1.4-1.0-0.60.91.4-1.11.4-1.4-0.91.21.11.4
Bone: cortical porosity4.44.79.0-2.02.21.7-0.2-2.1-1.63.0-2.22.22.6-2.7-2.3-2.3
Bone: cortical porosity5.25.610.6-2.32.42.0-0.4-2.4-1.83.3-2.52.42.5-2.7-2.5-2.5
Bone: cortical thickness0.61.01.51.2-1.2-1.10.31.00.8-0.81.2-1.2-0.70.91.01.1
Bone: cortical thickness0.20.21.20.3-0.2-0.41.10.3-0.7-0.20.2-0.2-0.30.40.0-0.1
Bone: cortical tissue density1.31.73.4-1.51.51.30.3-1.4-1.81.4-1.41.50.0-0.4-1.5-1.5
Bone: elastic displacement0.40.41.11.0-0.8-0.90.60.80.2-0.30.8-0.80.20.10.60.5
Bone: elastic work1.41.83.11.3-1.5-0.9-0.41.21.8-1.11.4-1.5-1.31.41.41.6
Bone: endosteal estimation0.41.02.70.8-1.0-0.6-1.40.51.6-1.01.0-1.0-0.40.70.81.2
Bone: endosteal perimeter0.30.53.00.3-0.5-0.1-1.70.11.4-0.60.5-0.5-0.10.20.40.7
Bone: final force0.61.02.70.4-0.8-0.3-0.90.51.7-0.90.9-0.8-1.31.20.91.2
Bone: final moment0.91.43.50.7-1.1-0.5-0.90.71.9-1.01.2-1.1-1.51.51.21.5
Bone: marrow area0.51.12.90.9-1.1-0.7-1.30.61.7-1.01.1-1.1-0.40.70.91.2
Bone: maximum diameter0.71.22.60.9-1.1-0.7-1.00.81.6-1.21.1-1.1-0.91.01.11.3
Bone: maximum force0.91.64.50.6-1.1-0.3-1.30.62.1-1.11.1-1.1-1.71.61.21.5
Bone: maximum moment1.22.05.20.8-1.3-0.5-1.30.82.3-1.11.3-1.3-1.81.81.31.7
Bone: minimum diameter0.50.95.50.1-0.50.2-2.4-0.12.0-0.20.5-0.5-0.30.20.50.9
Bone: periosteal estimation0.91.83.81.2-1.5-1.0-1.30.91.9-1.41.5-1.5-1.01.31.31.6
Bone: periosteal perimeter0.71.11.71.2-1.3-1.1-0.60.91.3-1.11.3-1.3-0.20.61.01.2
Bone: post-yield work0.50.64.0-0.80.41.0-2.0-0.81.10.3-0.30.4-0.2-0.1-0.30.1
Bone: stiffness0.50.92.80.0-0.50.1-1.00.21.4-1.00.5-0.5-1.71.40.71.0
Bone: tissue strength0.70.73.4-0.4-0.00.7-1.8-0.31.70.10.0-0.0-0.90.60.40.6
Bone: trabecular number0.71.12.90.4-0.8-0.3-0.70.61.7-1.00.8-0.8-1.51.51.01.3
Bone: trabecular spacing0.50.71.81.0-0.7-1.20.51.00.5-0.20.7-0.71.3-0.80.70.5
Bone: trabecular thickness0.30.42.6-0.1-0.10.2-0.10.00.1-0.30.1-0.1-1.61.30.20.3
Bone: trabecular tissue density1.11.67.01.4-1.0-1.72.61.4-1.3-0.81.1-1.0-0.30.80.70.3
Breakpoint value in progressive ratio session0.30.31.6-0.50.21.0-1.2-0.50.8-0.0-0.20.2-0.70.3-0.10.1
Distance traveled before self-admin0.00.00.10.3-0.1-0.2-0.10.2-0.10.20.1-0.10.00.00.10.1
Distance traveled after self-admin0.70.83.60.7-0.9-0.4-1.10.51.9-0.21.0-0.9-0.10.30.91.1
Delta time in closed arm before/after self-admin2.42.33.61.2-1.5-0.9-0.91.21.9-1.61.5-1.5-1.81.81.61.7
Delta time in open arm before/after self-admin0.60.51.9-0.30.5-0.31.1-0.2-0.90.7-0.40.51.4-1.1-0.5-0.6
Diff in mean of infusions in LGA sessions1.21.31.9-1.11.31.4-0.3-1.2-1.10.9-1.31.30.9-1.3-1.3-1.4
Extinction: sum of active levers before priming3.43.44.91.8-1.9-1.20.11.72.0-2.21.8-1.9-2.02.12.12.1
Active lever presses in extinction session 65.85.67.62.6-2.6-2.30.62.72.0-2.12.6-2.6-1.92.42.82.6
Delta distance traveled before/after self-admin1.11.24.80.6-1.0-0.4-1.30.62.2-0.81.1-1.0-0.60.71.11.4
Delta ambulatory time before/after self-admin1.21.35.50.6-1.0-0.3-1.80.52.3-0.81.1-1.0-0.50.61.11.4
Time in closed arm before self-admin3.03.45.3-1.92.11.6-0.0-1.8-1.92.3-2.02.11.5-1.8-2.0-2.1
Time in closed arm after self-admin0.20.20.5-0.60.60.7-0.7-0.50.20.4-0.60.6-0.40.0-0.3-0.3
Time in open arm before self-admin4.04.36.32.3-2.5-1.9-0.62.02.5-2.22.4-2.5-0.91.42.22.4
Time in open arm after self-admin0.91.01.81.2-1.2-1.3-0.11.01.1-0.81.3-1.20.50.01.01.1
Sum of active levers in priming session hrs 5-60.20.20.70.3-0.4-0.1-0.20.30.3-0.50.5-0.4-0.80.70.40.4
Time to tail flick, vehicle, before self-admin0.80.81.4-1.01.10.80.1-0.9-1.20.7-1.01.10.3-0.5-1.0-1.0
Time to tail flick, vehicle, after self-admin0.40.43.00.00.3-0.50.40.1-0.10.5-0.20.31.7-1.3-0.2-0.3
Time to tail flick, test, before self-admin3.23.25.5-2.32.02.1-1.5-2.2-0.81.9-1.92.00.6-1.1-1.9-1.6
Time to tail flick, test, after self-admin0.10.10.2-0.40.40.3-0.1-0.5-0.2-0.1-0.40.40.4-0.4-0.5-0.3
Delta time to tail flick, vehicle, before/after SA0.40.42.20.5-0.3-0.7-0.10.50.90.20.3-0.31.5-1.00.40.3
Delta time to tail flick, test, before/after SA1.71.53.71.6-1.2-1.71.91.5-0.1-1.31.2-1.20.20.31.00.8
Ambulatory time before self-admin0.00.00.10.20.10.00.20.1-0.20.3-0.10.10.2-0.2-0.0-0.1
Ambulatory time after self-admin1.41.57.10.6-1.0-0.0-1.90.52.7-0.51.1-1.0-0.80.81.11.5
Total heroin consumption0.20.20.7-0.60.40.8-0.7-0.60.20.4-0.40.4-0.2-0.1-0.3-0.2
Area under the delay curve0.50.51.3-0.80.61.1-1.0-0.80.50.9-0.80.6-0.0-0.3-0.5-0.4
Delay disc. indifference point, 0s delay2.42.65.7-2.31.72.4-2.1-1.8-0.11.4-1.71.7-1.10.1-1.3-1.1
Delay disc. indifference point, 16s delay0.70.71.5-1.00.81.2-1.1-0.80.90.9-0.90.80.0-0.5-0.4-0.3
Delay disc. indifference point, 2s delay0.70.83.2-0.90.41.3-1.8-0.80.90.3-0.40.4-1.40.8-0.20.1
Delay disc. indifference point, 24s delay0.50.52.5-0.3-0.10.7-1.6-0.31.40.2-0.0-0.1-0.90.50.30.5
Delay disc. indifference point, 4s delay1.01.12.7-1.01.01.1-0.3-1.2-0.31.7-1.11.00.9-1.1-1.1-1.0
Delay disc. indifference point, 8s delay0.10.10.40.0-0.00.1-0.6-0.10.40.5-0.1-0.00.5-0.5-0.0-0.0
Delay discount exponential model param0.30.30.90.5-0.3-0.80.90.6-0.6-0.70.5-0.3-0.00.30.30.2
Delay discount hyperbolic model param0.30.41.00.6-0.4-1.01.00.7-0.6-0.70.6-0.40.20.20.40.3
Fecal boli incidents, locomotor time 10.70.82.7-0.30.70.21.6-0.2-1.51.1-0.70.70.7-0.7-0.6-0.9
Change in fecal boli incidents, locomotor task1.51.52.21.3-1.3-1.31.11.40.8-1.51.2-1.3-0.91.11.31.1
Time >=10cm from walls, locomotor time 10.00.00.1-0.30.2-0.20.30.10.0-0.30.10.20.1-0.10.10.0
Bouts of movement, locomotor time 10.91.02.7-1.10.81.5-1.6-1.30.11.2-1.00.80.0-0.4-0.9-0.6
Total resting periods, locomotor time 10.60.71.8-0.90.71.2-1.3-1.10.11.1-0.90.70.1-0.5-0.8-0.6
Rest time, locomotor task time 10.40.41.4-0.50.70.51.2-0.2-0.90.6-0.60.7-0.50.2-0.4-0.6
Distance moved, locomotor task time 10.10.10.60.2-0.30.0-0.8-0.20.0-0.50.2-0.3-0.00.0-0.10.0
Vertical activity count, locomotor time 10.50.51.90.6-0.9-0.1-1.40.11.3-0.50.5-0.9-0.00.10.40.7
Time >=10cm from walls, locomotor time 21.21.22.7-0.91.00.70.8-1.0-1.61.3-1.11.00.9-1.0-1.3-1.4
Bouts of movement, locomotor time 20.20.20.7-0.10.10.2-0.3-0.5-0.30.6-0.40.10.8-0.7-0.5-0.4
Total resting periods, locomotor time 20.30.31.30.00.0-0.00.1-0.4-0.40.6-0.30.01.2-0.9-0.5-0.5
Rest time, locomotor task time 20.20.20.8-0.20.40.10.9-0.1-0.70.5-0.40.40.6-0.5-0.4-0.5
Distance moved, locomotor task time 20.20.30.7-0.40.30.7-0.8-0.8-0.40.4-0.40.3-0.0-0.2-0.7-0.5
Vertical activity count, locomotor time 20.30.31.8-0.1-0.20.6-1.3-0.40.80.1-0.0-0.2-0.70.4-0.00.2
Weight adjusted by age0.20.30.50.7-0.7-0.3-0.10.30.4-0.60.6-0.7-0.60.60.40.5
Seeking ratio, delayed vs. immediate footshock0.80.95.4-1.00.51.3-2.3-0.91.00.6-0.70.5-0.50.1-0.3-0.1
Locomotion in novel chamber0.20.21.10.30.1-0.51.00.2-0.6-0.1-0.10.10.9-0.6-0.1-0.3
Locomotion in novel chamber post-restriction0.00.00.10.1-0.1-0.10.20.1-0.0-0.4-0.0-0.10.1-0.10.1-0.0
Progressive ratio0.30.31.5-0.30.4-0.00.1-0.3-0.20.9-0.20.41.2-1.0-0.4-0.3
Food seeking constrained by brief footshock0.60.83.10.6-0.8-0.6-1.00.61.8-0.31.0-0.80.10.20.91.1
Seeking ratio, punishment vs. effort0.20.20.9-0.2-0.00.4-1.0-0.10.8-0.10.0-0.0-0.70.50.20.3
Run reversals in cocaine runway, females0.30.31.0-0.0-0.30.5-1.0-0.10.8-0.40.1-0.3-0.90.70.20.4
Run reversals in cocaine runway, males3.02.96.22.1-1.7-2.52.42.20.5-1.21.9-1.7-0.20.91.71.4
Latency to leave start box in cocaine runway0.60.61.8-1.00.61.2-1.4-0.70.20.5-0.60.6-1.10.6-0.2-0.2
Latency to leave start box in cocaine runway, F0.70.71.8-1.20.81.3-1.0-1.0-0.00.7-0.90.8-1.10.5-0.6-0.4
Latency to leave start box in cocaine runway, M0.10.10.20.2-0.1-0.2-0.40.40.1-0.20.3-0.10.00.00.40.3
Cd content in liver0.30.30.60.8-0.6-0.80.10.70.3-0.00.6-0.60.4-0.10.60.5
Co content in liver0.10.10.4-0.20.30.20.60.0-0.3-0.2-0.30.3-0.20.1-0.1-0.2
Cu content in liver0.40.52.0-0.2-0.20.3-0.70.20.9-0.60.2-0.2-1.41.10.50.6
Fe content in liver0.10.10.2-0.40.40.2-0.1-0.3-0.20.4-0.40.40.4-0.4-0.3-0.3
K content in liver0.10.10.3-0.20.30.20.1-0.20.20.3-0.30.30.5-0.5-0.2-0.2
Mg content in liver0.20.21.2-0.30.40.11.1-0.2-0.50.1-0.40.40.0-0.0-0.3-0.4
Mn content in liver0.50.63.30.6-0.1-0.91.80.5-0.80.00.1-0.11.3-0.9-0.0-0.3
Na content in liver0.30.32.3-0.4-0.00.4-1.5-0.31.00.30.0-0.00.2-0.20.00.2
Rb content in liver0.81.02.3-1.51.31.5-0.7-1.0-0.20.5-1.31.3-0.5-0.1-0.8-0.8
Se content in liver1.92.37.8-1.11.50.62.4-0.9-2.81.0-1.51.50.6-0.8-1.5-1.8
Sr content in liver0.30.31.10.3-0.0-0.51.10.1-0.80.50.0-0.00.9-0.6-0.3-0.4
Zn content in liver0.20.20.8-0.60.40.60.2-0.2-0.00.1-0.40.4-0.90.6-0.1-0.1