Vps51

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000020996 0.1 0.05 3.8e-08 0.04 0.04 0.04 0.03 5.2e-05 3.6e-05 3.5e-05 1.1e-04
2 BLA gene expression ENSRNOG00000020996 0.59 0.13 5.1e-14 0.22 0.23 0.23 0.23 6.3e-12 2.7e-12 1.1e-12 9.1e-13
3 Brain gene expression ENSRNOG00000020996 0.47 0.13 0.0e+00 0.26 0.29 0.3 0.3 1.1e-23 2.4e-27 6.9e-28 2.0e-28
4 Brain mRNA stability ENSRNOG00000020996 0.06 0.06 8.9e-03 0.02 0.02 0.02 0.02 7.2e-03 1.0e-02 2.7e-03 5.9e-03
5 Eye mRNA stability ENSRNOG00000020996 0.43 0.19 3.4e-03 -0 0.01 -0.01 -0.01 3.6e-01 1.9e-01 5.0e-01 5.0e-01
6 Liver gene expression ENSRNOG00000020996 0.1 0.05 9.0e-10 0.03 0.06 0.06 0.04 1.7e-04 8.9e-07 5.8e-07 9.2e-06
7 Liver intron excision ratio chr1:203364141:203369571 0.18 0.08 1.5e-15 0.1 0.09 0.08 0.1 3.2e-11 8.5e-10 1.6e-09 7.9e-11
8 Liver intron excision ratio chr1:203365440:203369571 0.14 0.06 2.1e-13 0.09 0.07 0.07 0.08 8.2e-10 2.1e-08 5.4e-08 9.0e-09
9 Liver mRNA stability ENSRNOG00000020996 0.09 0.04 8.2e-09 0.06 0.05 0.05 0.05 2.8e-07 5.5e-06 4.1e-06 2.8e-06
10 NAcc gene expression ENSRNOG00000020996 0.17 0.1 1.7e-07 0.1 0.06 0.06 0.07 1.2e-07 5.0e-05 3.1e-05 7.3e-06
11 PL gene expression ENSRNOG00000020996 0.33 0.12 3.4e-15 0.14 0.17 0.16 0.17 8.3e-11 4.9e-13 2.5e-12 7.7e-13

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail4.113.325.9-4.1-5.1-4.2-4.02.0-4.1-3.03.02.7-2.1-4.3
BMI without tail1.53.15.4-2.0-2.3-1.9-1.71.4-2.2-1.41.41.5-0.5-2.0
Body weight2.29.418.7-1.2-3.0-1.7-1.73.8-4.3-4.24.24.00.4-1.6
Epididymis fat weight2.15.08.4-1.7-1.1-1.8-1.8-2.72.12.7-2.7-2.7-2.9-1.5
Glucose2.33.65.0-2.0-1.6-2.0-1.9-2.01.31.8-1.8-2.0-2.2-1.9
Heart weight2.13.06.1-0.90.0-0.8-0.6-2.12.42.5-2.5-2.4-1.7-0.6
Left kidney weight0.41.22.5-0.7-0.4-0.7-0.7-1.61.01.4-1.4-1.5-1.2-0.6
Right kidney weight0.10.31.0-0.0-0.3-0.2-0.6-0.90.30.5-0.5-0.6-1.0-0.2
Tail length1.23.55.92.41.72.12.12.1-0.5-1.21.21.52.42.3
Length with tail1.34.910.11.90.41.31.23.2-2.1-2.92.93.02.21.5
Length without tail1.22.77.10.5-0.80.0-0.02.2-1.9-2.72.72.30.70.3
Liver weight, left0.10.20.7-0.5-0.5-0.5-0.6-0.20.20.2-0.2-0.2-0.8-0.4
Liver weight, right0.20.30.7-0.5-0.9-0.8-0.70.20.50.3-0.3-0.2-0.8-0.4
Parametrial fat weight2.65.18.9-2.3-1.8-2.5-2.3-2.51.22.1-2.1-2.2-3.0-2.3
Retroperitoneal fat weight3.812.521.3-2.6-1.2-2.4-2.2-4.63.84.5-4.5-4.6-4.2-1.9
Intraocular pressure0.70.91.81.20.80.60.3-1.21.31.1-1.1-1.3-0.20.6
Extensor digitorum longus weight4.015.935.10.1-2.2-0.3-0.55.4-5.7-5.85.85.92.1-0.6
Soleus weight2.36.714.2-1.1-0.0-1.0-0.8-3.43.43.7-3.7-3.8-2.2-0.6
Tibialis anterior weight5.719.842.61.8-1.30.80.46.3-5.8-6.56.56.53.30.8
Tibia length0.51.53.70.6-1.1-0.2-0.81.2-1.9-1.81.81.70.3-0.3
Number of licking bursts0.20.20.60.0-0.10.0-0.00.4-0.8-0.70.70.70.4-0.1
Food consumed during 24 hour testing period0.30.41.01.00.80.90.70.1-0.0-0.20.20.20.70.8
Times rat made contact with spout0.50.61.60.50.70.81.00.8-0.6-0.70.70.71.30.5
Mean time between licks in bursts0.60.82.10.80.70.90.91.40.1-1.01.00.51.00.9
Mean num. licks in bursts0.20.30.50.30.70.50.7-0.20.70.6-0.6-0.50.30.5
Std. dev. time between licks in bursts0.30.41.30.50.70.60.80.51.10.1-0.1-0.50.30.9
Water consumed over 24 hours1.31.63.01.31.31.51.61.1-0.7-1.01.01.01.71.3
Indifference point 0 sec0.00.00.1-0.20.0-0.10.0-0.30.10.1-0.1-0.2-0.1-0.1
Indifference point AUC1.92.24.70.90.20.80.31.8-2.2-2.12.12.11.10.4
Indifference point function ln k4.56.315.0-1.00.5-0.7-0.2-2.93.93.7-3.7-3.6-2.0-0.2
Indifference point function log k4.56.315.0-1.00.5-0.7-0.2-2.93.93.7-3.7-3.6-2.0-0.2
Delay discounting total patch changes 0 sec0.10.10.20.30.40.30.5-0.00.30.0-0.0-0.20.30.4
Delay discounting total patch changes 12 sec2.53.47.70.5-0.20.50.32.2-2.8-2.72.72.61.50.1
Delay discounting total patch changes 18 sec0.30.41.4-0.2-0.5-0.3-0.50.5-1.2-0.90.90.80.0-0.5
Delay discounting total patch changes 24 sec1.62.03.51.20.40.90.71.9-1.5-1.81.81.81.40.8
Delay discounting total patch changes 6 sec0.40.71.8-0.0-0.20.0-0.01.1-1.1-1.41.41.00.4-0.1
Delay discounting time to switch 0 sec2.33.46.9-1.9-2.4-1.9-1.80.9-2.6-1.81.81.7-0.6-2.0
Delay discounting water rate 0 sec2.84.512.01.32.01.31.2-2.03.52.6-2.6-2.8-0.31.6
Delay discounting water rate 12 sec5.68.422.41.42.81.71.8-2.54.73.9-3.9-3.7-0.22.1
Delay discounting water rate 18 sec1.82.47.60.30.90.20.4-1.42.82.2-2.2-2.1-0.70.6
Delay discounting water rate 24 sec2.53.410.10.61.30.60.6-1.73.22.6-2.6-2.5-0.81.0
Delay discounting water rate 6 sec2.74.013.11.01.70.91.1-1.53.62.5-2.5-2.8-0.31.4
Locomotor activity1.42.26.60.91.61.01.0-1.02.61.8-1.8-2.0-0.11.2
Locomotor testing distance2.13.410.11.22.01.31.3-1.13.22.2-2.2-2.3-0.11.6
Locomotor testing rearing1.52.46.20.81.61.01.0-1.12.52.1-2.1-1.9-0.21.1
Light reinforcement 10.30.61.40.91.20.91.0-0.30.60.6-0.6-0.50.60.9
Light reinforcement 20.60.81.9-0.3-0.5-0.7-0.8-1.40.71.2-1.2-1.0-1.1-0.4
Reaction time number correct0.30.41.01.00.30.50.50.9-0.1-0.50.50.70.60.7
Reaction time mean minus median1.82.36.1-0.0-1.2-0.4-0.61.5-2.5-2.32.32.20.2-0.5
Reaction time mean minus median AUC0.91.12.50.5-0.50.1-0.11.2-1.5-1.61.61.60.40.1
Reaction time num false alarms0.30.41.60.40.80.50.80.01.30.5-0.5-0.60.30.7
Reaction time num false alarms AUC0.20.30.90.50.80.60.90.60.5-0.20.20.10.70.7
Reaction time trials correct on left0.30.41.01.00.30.50.50.9-0.1-0.50.50.70.60.7
Reaction time trials on left0.30.51.21.10.30.60.51.0-0.2-0.60.60.70.70.7
Reaction time mean0.00.10.20.2-0.10.00.0-0.2-0.5-0.30.30.4-0.1-0.1
Reaction time mean AUC0.10.10.30.1-0.2-0.1-0.1-0.4-0.5-0.20.20.3-0.2-0.2
Median of all reaction times0.00.10.40.10.0-0.10.0-0.6-0.00.2-0.2-0.1-0.2-0.1
Reaction time omissions0.60.91.90.7-0.10.40.51.1-1.2-1.41.41.10.80.3
Reaction time false alarm rate0.10.20.7-0.10.40.10.4-0.10.90.4-0.4-0.60.10.3
Reaction time premature initiation rate1.92.66.41.20.71.41.42.5-1.1-1.81.81.91.81.3
Reaction time premature initiations3.34.79.82.01.12.01.93.1-1.4-2.32.32.52.51.9
Std. dev. reaction times0.50.61.80.3-0.5-0.0-0.00.6-1.3-1.21.21.20.2-0.1
Reaction time trials completed0.30.51.21.10.30.60.51.0-0.2-0.60.60.70.70.7
Reaction time trials AUC0.20.30.80.90.20.50.40.80.0-0.40.40.50.50.6
Social response proportion0.60.61.60.0-0.40.1-0.10.9-1.1-1.31.31.10.7-0.1
Social responses0.30.41.00.60.30.60.60.7-0.2-0.60.60.61.00.6
Social time0.40.51.00.80.30.70.61.0-0.2-0.60.60.70.90.7
Conditioned locomotion0.81.02.40.3-0.40.10.11.6-1.0-1.51.51.40.80.2
Cocaine response after cond. corrected0.91.02.7-0.5-0.1-0.5-0.2-0.91.61.5-1.5-1.4-0.8-0.1
Cocaine response after cond. not corrected0.80.92.1-0.5-0.3-0.6-0.4-0.81.41.3-1.3-1.3-1.0-0.3
Cocaine response before conditioning0.30.41.30.3-0.30.1-0.10.6-1.1-1.01.00.80.2-0.1
Saline control response2.22.96.80.5-0.40.30.32.6-2.0-2.62.62.31.40.3
Condit. Reinf. active minus inactive responses0.30.41.0-0.4-0.6-0.7-0.8-0.80.10.4-0.4-0.5-1.0-0.7
Condit. Reinf. active-inactive response ratio1.92.04.2-1.2-1.7-1.7-1.9-1.40.20.9-0.9-0.9-2.0-1.6
Condit. Reinf. active responses0.10.10.2-0.2-0.3-0.3-0.2-0.2-0.4-0.20.20.0-0.3-0.4
Condit. Reinf. inactive responses0.30.41.00.20.70.60.90.6-0.6-0.60.60.51.00.4
Condit. Reinf. lever presses1.11.53.6-0.1-1.1-0.4-0.71.2-1.9-1.81.81.60.1-0.6
Condit. Reinf. lever reinforcers received0.10.10.60.0-0.2-0.0-0.10.1-0.8-0.60.60.40.0-0.2
Pavlov. Cond. lever latency0.40.61.30.41.10.70.9-0.50.90.8-0.8-0.70.40.7
Pavlov. Cond. magazine entry latency1.92.15.6-0.1-0.60.0-0.01.7-2.4-2.12.12.11.1-0.3
Pavlov. Cond. change in total contacts1.01.55.0-0.4-1.1-0.5-0.80.7-2.2-1.61.61.50.1-0.9
Pavlov. Cond. index score1.31.74.9-0.4-1.2-0.5-0.71.2-2.2-1.81.81.80.3-0.7
Pavlov. Cond. latency score1.21.54.0-0.5-1.3-0.7-0.91.0-2.0-1.61.61.60.1-0.9
Pavlov. Cond. lever contacts0.20.30.70.3-0.5-0.1-0.30.6-0.7-0.90.90.70.2-0.0
Pavlov. Cond. magazine entry number3.34.110.7-0.20.7-0.3-0.1-2.33.33.0-3.0-2.9-1.50.2
Pavlov. Cond. intertrial magazine entries0.70.91.8-0.3-0.1-0.5-0.4-1.21.31.4-1.4-1.2-0.9-0.2
Pavlov. Cond. lever-magazine prob. diff.1.62.05.7-0.3-1.1-0.4-0.61.4-2.4-2.02.02.00.5-0.6
Pavlov. Cond. response bias0.91.23.00.2-0.7-0.1-0.31.2-1.7-1.71.71.50.6-0.2
Conditioned reinforcement - actives0.20.20.40.4-0.1-0.2-0.4-0.70.40.6-0.6-0.4-0.6-0.1
Conditioned reinforcement - inactives3.33.89.40.31.0-0.0-0.1-3.12.52.7-2.7-2.8-1.6-0.0
Conditioned locomotion4.65.511.30.51.20.20.1-3.33.43.4-3.4-3.3-1.70.4
Intermittent access intake day 1-15 change0.50.51.00.90.70.50.3-0.91.00.8-0.8-0.9-0.10.6
Intermittent access intake escalation0.40.40.90.60.40.30.1-0.90.80.7-0.7-0.8-0.30.3
Intermittent access intake escalation 20.40.41.31.10.90.80.6-0.50.50.3-0.3-0.40.30.7
Intermitt. access day 1 inactive lever presses1.41.53.6-0.40.3-0.2-0.2-1.91.51.7-1.7-1.7-1.2-0.3
Intermitt. access day 15 inactive lever presses1.71.84.7-0.20.2-0.5-0.6-2.21.51.8-1.8-1.8-1.7-0.4
Intermitt. access escalation Index2.21.93.9-1.7-0.3-0.9-0.5-1.71.42.0-2.0-1.8-1.0-0.8
Intermittent access day 1 total infusions6.97.815.1-2.7-2.0-2.9-2.8-3.11.62.8-2.8-2.6-3.9-2.7
Intermittent access day 15 total infusions6.37.013.1-1.3-0.8-1.8-1.9-3.62.73.4-3.4-3.3-3.5-1.6
Intermittent access terminal intake (last 3 days)5.76.213.0-1.7-1.5-2.2-2.4-3.11.92.8-2.8-2.7-3.6-1.9
Intermittent access total infusions5.66.212.6-2.1-1.7-2.5-2.5-3.01.62.6-2.6-2.5-3.5-2.3
Intermittent access day 1 locomotion5.45.510.3-2.5-1.8-2.6-2.4-2.31.42.3-2.3-2.1-3.2-2.4
Intermittent access day 15 total locomotion3.84.08.3-0.9-0.5-1.3-1.4-2.91.92.5-2.5-2.5-2.6-1.3
Intermittent access total locomotion7.48.316.5-2.5-2.0-2.9-2.9-3.41.82.9-2.9-2.9-4.1-2.8
Intermittent access standard deviation0.70.81.60.40.40.1-0.1-1.31.21.3-1.3-1.2-0.70.2
Cocaine induced anxiety0.00.00.20.1-0.3-0.3-0.4-0.0-0.10.0-0.00.1-0.2-0.2
Post-drug Anxiety0.60.71.50.7-0.40.1-0.21.1-1.0-1.21.21.20.40.2
Baseline Anxiety1.61.63.31.00.20.70.51.8-1.3-1.81.81.61.30.6
Lifetime Intake5.15.711.2-2.1-1.7-2.5-2.4-2.71.52.4-2.4-2.3-3.4-2.2
Incentive Sensitization - Responses0.60.61.2-0.4-0.4-0.7-0.8-1.10.40.7-0.7-0.8-1.1-0.7
Incentive Sensitization - Breakpoint0.70.71.7-0.4-0.3-0.7-0.8-1.30.60.9-0.9-1.0-1.2-0.7
Progressive ratio test 1 active lever presses2.02.14.3-0.50.1-0.6-0.6-2.01.72.1-2.1-1.9-1.5-0.4
Progressive ratio test 1 breakpoint1.71.83.9-0.40.2-0.4-0.4-1.91.72.0-2.0-1.8-1.3-0.2
Progressive ratio test 1 inactive lever presses0.70.81.8-0.30.4-0.10.1-1.31.11.3-1.3-1.2-0.6-0.1
Progressive ratio test 2 active lever presses3.33.57.4-0.7-0.3-1.1-1.2-2.71.92.5-2.5-2.4-2.4-1.0
Progressive ratio test 2 breakpoint3.53.98.4-0.30.3-0.6-0.7-2.92.42.8-2.8-2.8-2.1-0.5
Progressive ratio test 2 inactive lever presses5.86.715.0-1.2-0.1-1.3-1.3-3.92.73.5-3.5-3.4-3.0-1.2
Total sessions with >9 infusions2.42.75.1-1.7-1.3-1.8-1.7-1.61.21.5-1.5-1.6-2.3-1.6
Short access day 1 total inactive lever presses2.52.85.7-0.70.1-0.8-0.7-2.42.12.2-2.2-2.4-1.8-0.7
Short access day 10 total inactive lever presses2.02.25.10.11.10.20.4-1.92.32.1-2.1-2.2-0.80.3
Short access day 1 total infusions3.53.75.5-2.2-1.4-2.1-1.8-2.21.12.0-2.0-1.8-2.3-2.0
Short access day 10 total infusions4.75.29.8-2.7-2.4-3.0-2.8-1.90.41.5-1.5-1.4-3.1-2.8
Short access total infusions3.03.36.4-2.0-1.7-2.2-2.1-1.50.71.5-1.5-1.3-2.5-2.0
Short access day 1 locomotion3.03.25.5-1.7-1.4-1.9-1.8-1.91.11.8-1.8-1.7-2.3-1.8
Short access day 10 total locomotion2.32.53.6-1.9-1.3-1.8-1.6-1.70.91.6-1.6-1.5-1.8-1.7
Short access total locomotion2.22.33.8-1.8-1.3-1.7-1.5-1.50.71.5-1.5-1.3-1.9-1.7
Compulsive drug intake3.53.47.61.21.42.02.22.2-1.1-1.81.81.72.81.8
One hour access (0.3 mA shock)6.57.614.9-0.70.0-1.2-1.3-3.93.33.8-3.8-3.8-3.1-0.9
One hour access (shock baseline)6.67.615.9-0.8-0.5-1.6-1.9-4.02.83.6-3.6-3.5-3.5-1.4
Number of responses in last shaping day0.90.92.30.40.80.50.5-0.91.51.4-1.4-1.2-0.20.6
Context. condit. distance diff. score1.11.32.6-0.7-0.0-0.6-0.2-1.41.51.6-1.6-1.6-1.0-0.3
Locomotion velocity, session 10.10.10.30.50.30.30.40.50.2-0.00.00.20.20.5
Locomotion distance, session 10.60.71.3-0.9-1.1-1.0-0.70.7-1.1-0.70.70.7-0.1-1.0
Locomotion velocity, session 21.61.94.5-0.5-1.0-0.5-0.61.7-2.1-1.81.81.90.7-0.7
Locomotion distance, session 20.40.61.5-0.7-0.7-0.6-0.30.9-1.2-0.80.80.90.4-0.7
Locomotion velocity, session 31.21.43.1-1.5-1.7-1.8-1.5-0.40.10.4-0.4-0.5-1.5-1.5
Locomotion distance, session 30.00.10.1-0.1-0.2-0.3-0.2-0.10.20.2-0.2-0.3-0.3-0.2
Stereotopy head waving bouts, day 31.51.93.6-1.7-1.7-1.9-1.6-0.60.70.8-0.8-0.8-1.9-1.5
Stereotopy head waving duration, day 30.91.11.7-1.1-1.0-1.2-1.1-0.80.90.9-0.9-1.0-1.3-1.0
Locomotion velocity, session 71.92.14.4-2.0-1.7-2.1-1.7-1.1-0.00.8-0.8-0.7-1.5-1.9
Locomotion distance, session 70.30.41.2-1.0-0.8-1.1-0.5-0.20.10.2-0.2-0.3-0.5-0.8
Stereotopy head waving bouts, day 70.50.61.0-1.0-0.9-0.9-1.0-0.7-0.20.4-0.4-0.3-0.9-1.0
Stereotopy head waving duration, day 70.80.92.8-0.8-0.9-0.5-0.80.6-1.7-1.11.11.20.0-0.9
Locomotion velocity, session 80.60.72.30.50.10.50.41.5-0.5-1.11.11.10.70.6
Locomotion distance, session 80.81.22.9-1.4-1.5-1.7-1.4-0.50.00.5-0.5-0.5-1.2-1.4
Degree of sensitization distance0.70.71.8-1.2-1.2-1.4-1.1-0.2-0.20.0-0.0-0.1-0.8-1.1
Degree of sensitization stereotypy0.40.51.6-0.5-0.7-0.4-0.70.2-1.3-0.70.70.8-0.2-0.7
Condit. Reinf. active minus inactive responses0.10.10.4-0.10.10.00.10.3-0.6-0.40.40.40.4-0.1
Condit. Reinf. active-inactive response ratio0.20.20.60.40.80.70.80.1-0.2-0.20.20.10.60.4
Condit. Reinf. active responses0.20.30.7-0.6-0.7-0.7-0.6-0.1-0.6-0.20.20.1-0.2-0.8
Condit. Reinf. inactive responses1.11.32.9-1.3-1.6-1.7-1.7-0.5-0.30.2-0.2-0.2-1.1-1.6
Incentive salience index mean0.40.41.0-0.7-0.7-0.7-0.60.4-1.0-0.60.60.6-0.0-0.8
Condit. Reinf. lever presses0.60.81.9-0.8-1.4-1.1-1.20.4-1.0-0.70.70.6-0.5-1.1
Time in familiar zone, hab. session 10.60.51.1-0.9-0.7-0.8-0.9-0.60.20.5-0.5-0.5-1.1-0.8
Time in novel zone, hab. session 10.70.71.31.01.10.91.10.11.00.3-0.3-0.40.61.1
Total zone transitions, hab. session 10.40.51.80.1-0.10.10.20.7-1.3-1.01.01.10.8-0.1
Total locomotion distance, hab. session 10.50.81.6-1.0-1.0-1.3-1.0-0.80.00.7-0.7-0.6-0.9-1.1
Locomotion velocity, hab. session 10.20.40.9-0.7-0.8-1.0-0.7-0.3-0.40.2-0.2-0.1-0.3-0.9
Time in familiar zone, hab. session 20.20.20.60.40.40.50.50.60.70.0-0.0-0.10.40.7
Time in novel zone, hab. session 20.10.10.5-0.3-0.2-0.2-0.1-0.2-0.7-0.20.20.2-0.1-0.5
Total zone transitions, hab. session 21.41.84.3-1.3-1.6-1.4-1.01.0-2.1-1.31.31.40.1-1.5
Total locomotion distance, hab. session 21.01.33.2-1.7-1.6-1.8-1.4-0.2-0.60.1-0.1-0.0-0.9-1.7
Locomotion velocity, hab. session 21.41.94.4-1.9-1.9-2.1-1.8-0.5-0.50.3-0.3-0.2-1.2-2.0
Novel to familiar place preference ratio0.70.83.2-0.0-0.6-0.3-0.40.5-1.8-1.11.11.20.1-0.6
Novelty place preference0.40.41.9-0.1-0.4-0.2-0.30.1-1.4-0.70.70.8-0.0-0.5
Time in novel zone, NPP test0.30.31.4-0.1-0.4-0.1-0.30.1-1.2-0.60.60.7-0.1-0.4
Total zone transitions, NPP test1.42.05.6-0.4-1.0-0.5-0.51.6-2.4-1.91.92.00.7-0.7
Total locomotion distance, NPP test0.40.51.2-1.0-1.0-1.1-0.80.1-0.7-0.20.20.2-0.5-1.1
Locomotion velocity, NPP test0.30.40.9-0.9-0.8-0.9-0.70.1-0.8-0.30.30.3-0.2-0.9
Pavlov. Cond. lever latency0.40.50.90.70.90.80.8-0.40.90.5-0.5-0.60.20.8
Pavlov. Cond. magazine entry latency0.40.51.4-0.9-0.8-0.8-0.70.0-1.2-0.40.40.5-0.4-1.1
Pavlov. Cond. change in total contacts0.30.31.1-0.6-0.6-0.5-0.6-0.4-1.1-0.20.20.3-0.2-0.8
Pavlov. Cond. index score0.10.10.7-0.2-0.3-0.2-0.20.2-0.8-0.40.40.50.2-0.3
Pavlov. Cond. latency score0.10.20.5-0.5-0.5-0.5-0.40.1-0.7-0.20.20.3-0.1-0.6
Pavlov. Cond. lever contacts0.10.10.3-0.5-0.5-0.5-0.40.1-0.3-0.10.10.1-0.2-0.5
Pavlov. Cond. magazine entry number0.20.20.8-0.4-0.2-0.3-0.3-0.20.90.5-0.5-0.6-0.5-0.1
Pavlov. Cond. intertrial magazine entries0.40.50.90.50.80.60.5-1.00.80.7-0.7-0.90.30.5
Pavlov. Cond. lever-magazine prob. diff.0.20.31.3-0.3-0.4-0.3-0.30.4-1.1-0.60.60.70.2-0.4
Pavlov. Cond. response bias0.10.10.40.10.10.10.10.1-0.6-0.30.30.40.3-0.0
Bone: apparent density1.21.93.9-1.9-2.0-1.7-1.60.2-1.5-0.70.70.7-0.9-1.8
Bone surface3.15.412.7-1.2-2.7-1.6-2.02.0-3.6-2.82.82.8-0.4-1.8
Bone volume1.93.26.3-1.6-2.4-1.8-2.10.7-2.5-1.51.51.6-1.0-2.0
Bone: connectivity density1.82.86.2-1.4-2.0-1.4-1.41.4-2.5-1.91.91.9-0.1-1.5
Bone: cortical apparent density0.81.02.01.11.41.41.40.5-0.4-0.60.60.51.31.0
Bone: cortical area0.40.51.1-0.1-0.9-0.3-0.60.8-1.1-1.01.01.0-0.1-0.3
Bone: cortical porosity0.20.20.5-0.7-0.6-0.5-0.40.1-0.6-0.30.30.3-0.1-0.6
Bone: cortical porosity0.40.41.1-0.5-0.5-0.2-0.20.7-1.0-0.90.90.80.3-0.4
Bone: cortical thickness2.03.45.61.61.11.71.62.4-1.4-2.12.12.12.11.5
Bone: cortical thickness1.21.42.41.41.31.51.51.3-0.0-0.70.70.71.21.5
Bone: cortical tissue density1.01.22.31.21.51.51.50.7-0.5-0.70.70.61.41.1
Bone: elastic displacement1.61.84.41.31.71.31.4-0.42.11.2-1.2-1.30.41.6
Bone: elastic work0.81.02.11.10.81.11.11.5-0.0-0.80.80.71.01.2
Bone: endosteal estimation2.86.010.6-2.9-3.2-3.2-3.3-1.60.31.3-1.3-1.3-3.2-2.9
Bone: endosteal perimeter3.36.812.6-2.9-3.3-3.3-3.5-2.00.31.5-1.5-1.4-3.5-3.0
Bone: final force1.72.85.8-0.4-1.6-0.7-0.92.0-2.4-2.42.42.30.2-0.7
Bone: final moment1.52.55.1-0.4-1.5-0.7-0.91.9-2.3-2.22.22.20.2-0.7
Bone: marrow area2.86.110.6-3.0-3.2-3.2-3.3-1.60.41.4-1.4-1.3-3.2-2.9
Bone: maximum diameter0.50.92.6-0.5-1.6-1.0-1.50.2-0.8-0.50.50.5-1.1-0.9
Bone: maximum force2.84.99.4-1.5-2.8-1.9-2.11.8-3.1-2.62.62.4-0.8-2.0
Bone: maximum moment2.54.38.1-1.5-2.7-1.8-2.01.7-2.8-2.32.32.2-0.8-1.9
Bone: minimum diameter2.44.48.0-2.8-2.5-2.6-2.6-1.60.01.2-1.2-1.1-2.6-2.7
Bone: periosteal estimation1.42.86.8-1.9-2.6-2.2-2.5-0.5-0.50.2-0.2-0.1-2.1-2.0
Bone: periosteal perimeter0.81.43.7-1.2-1.9-1.5-1.8-0.0-0.8-0.30.30.4-1.3-1.4
Bone: post-yield work7.09.518.8-3.9-4.3-4.2-4.1-0.8-2.5-0.70.70.6-3.0-4.3
Bone: stiffness2.33.68.3-1.3-2.3-1.5-1.71.4-2.9-2.22.22.2-0.4-1.7
Bone: tissue strength0.10.10.1-0.2-0.3-0.3-0.3-0.1-0.2-0.20.2-0.0-0.2-0.3
Bone: trabecular number1.11.63.4-1.5-1.8-1.6-1.50.1-1.6-0.80.80.9-0.7-1.6
Bone: trabecular spacing0.40.51.20.71.10.80.9-0.10.90.6-0.6-0.50.50.8
Bone: trabecular thickness0.70.91.6-1.3-0.7-0.9-0.9-1.10.30.8-0.8-0.8-1.0-1.0
Bone: trabecular tissue density1.82.55.4-0.10.60.0-0.0-2.22.22.3-2.3-2.3-1.10.1
Breakpoint value in progressive ratio session1.71.94.50.4-0.30.30.11.6-2.0-2.12.11.91.10.0
Distance traveled before self-admin0.40.41.4-0.1-0.6-0.3-0.30.5-1.2-0.80.81.00.4-0.3
Distance traveled after self-admin0.20.20.50.20.20.40.20.2-0.6-0.60.60.50.70.1
Delta time in closed arm before/after self-admin0.10.10.50.50.40.20.40.70.4-0.10.10.10.30.4
Delta time in open arm before/after self-admin0.10.10.30.30.40.50.2-0.2-0.4-0.30.30.30.40.2
Diff in mean of infusions in LGA sessions0.50.61.61.30.60.70.70.7-0.5-0.70.70.60.90.7
Extinction: sum of active levers before priming2.72.77.6-0.3-0.8-0.2-0.21.8-2.8-2.42.42.31.0-0.5
Active lever presses in extinction session 61.51.43.01.1-0.10.50.11.6-1.6-1.51.51.71.10.5
Delta distance traveled before/after self-admin0.20.20.50.30.70.60.50.00.60.1-0.1-0.30.30.5
Delta ambulatory time before/after self-admin0.30.30.80.50.90.70.70.20.5-0.00.0-0.20.60.7
Time in closed arm before self-admin0.20.30.6-0.6-0.8-0.6-0.7-0.2-0.5-0.20.20.2-0.4-0.7
Time in closed arm after self-admin0.10.10.3-0.3-0.3-0.5-0.3-0.10.20.0-0.0-0.3-0.3-0.4
Time in open arm before self-admin0.70.71.50.61.10.71.2-0.11.20.9-0.9-0.80.40.9
Time in open arm after self-admin0.80.91.90.91.41.31.4-0.20.70.5-0.5-0.31.01.2
Sum of active levers in priming session hrs 5-61.21.23.31.80.40.80.30.9-1.1-1.31.31.31.10.8
Time to tail flick, vehicle, before self-admin0.80.81.6-0.5-1.3-1.0-1.10.5-1.2-0.60.60.9-0.6-1.0
Time to tail flick, vehicle, after self-admin1.11.11.9-1.0-1.3-0.9-0.81.4-1.2-1.11.11.30.0-0.9
Time to tail flick, test, before self-admin1.61.62.9-1.7-1.2-1.6-1.4-0.80.70.9-0.9-0.9-1.7-1.5
Time to tail flick, test, after self-admin0.10.10.30.50.20.30.20.20.1-0.10.10.10.30.3
Delta time to tail flick, vehicle, before/after SA0.30.20.6-0.5-0.4-0.2-0.10.8-0.5-0.70.70.60.3-0.2
Delta time to tail flick, test, before/after SA3.32.95.52.31.62.21.91.3-0.6-1.11.11.22.42.0
Ambulatory time before self-admin0.40.41.0-0.3-0.7-0.4-0.60.2-1.0-0.70.70.7-0.1-0.5
Ambulatory time after self-admin0.20.20.5-0.6-0.2-0.4-0.6-0.7-0.30.1-0.1-0.2-0.2-0.7
Total heroin consumption3.23.88.00.7-0.30.60.62.5-2.7-2.82.82.71.90.3
Area under the delay curve0.10.10.3-0.5-0.1-0.3-0.2-0.2-0.20.3-0.3-0.1-0.3-0.5
Delay disc. indifference point, 0s delay0.40.40.9-0.8-0.2-0.6-0.5-0.40.31.0-1.0-0.5-0.9-0.7
Delay disc. indifference point, 16s delay0.60.61.8-0.70.0-0.4-0.3-1.30.40.9-0.9-1.1-0.7-0.6
Delay disc. indifference point, 2s delay0.20.30.5-0.6-0.5-0.6-0.7-0.30.00.4-0.4-0.3-0.6-0.6
Delay disc. indifference point, 24s delay0.40.30.90.70.90.70.80.20.50.3-0.3-0.20.50.7
Delay disc. indifference point, 4s delay0.10.10.3-0.10.4-0.10.1-0.10.30.5-0.5-0.3-0.0-0.2
Delay disc. indifference point, 8s delay0.00.00.1-0.30.1-0.10.30.10.20.3-0.3-0.10.00.0
Delay discount exponential model param0.00.00.10.3-0.00.20.10.10.2-0.30.30.10.10.4
Delay discount hyperbolic model param0.00.00.10.3-0.00.10.10.00.2-0.20.20.00.10.4
Fecal boli incidents, locomotor time 10.30.30.8-0.2-0.9-0.7-0.9-0.3-0.7-0.20.20.3-0.8-0.7
Change in fecal boli incidents, locomotor task0.10.10.2-0.4-0.2-0.4-0.40.40.4-0.00.0-0.1-0.5-0.3
Time >=10cm from walls, locomotor time 13.93.98.9-1.8-2.3-2.7-2.9-1.4-0.30.8-0.8-0.7-3.0-2.6
Bouts of movement, locomotor time 12.02.25.51.11.31.71.91.0-1.1-1.41.41.32.31.4
Total resting periods, locomotor time 11.21.43.80.80.91.31.40.7-1.1-1.21.21.02.00.9
Rest time, locomotor task time 10.70.82.10.30.30.1-0.1-1.11.41.3-1.3-1.3-0.50.2
Distance moved, locomotor task time 10.40.51.0-0.9-1.0-1.0-0.70.1-0.6-0.30.30.3-0.4-0.9
Vertical activity count, locomotor time 10.80.81.7-0.10.3-0.3-0.1-1.21.21.2-1.2-1.3-0.9-0.1
Time >=10cm from walls, locomotor time 20.10.10.4-0.0-0.2-0.2-0.3-0.2-0.6-0.10.10.4-0.1-0.4
Bouts of movement, locomotor time 20.60.71.10.70.91.01.10.5-0.6-0.90.90.70.90.6
Total resting periods, locomotor time 20.30.30.60.40.70.70.80.2-0.4-0.60.60.40.50.4
Rest time, locomotor task time 21.82.14.3-0.7-0.2-0.7-0.9-1.71.71.9-1.9-1.8-2.1-0.7
Distance moved, locomotor task time 20.91.02.10.70.20.60.81.2-1.1-1.21.21.21.50.6
Vertical activity count, locomotor time 21.01.12.21.51.31.31.40.50.8-0.00.0-0.21.11.5
Weight adjusted by age1.21.32.90.9-0.30.20.11.5-1.6-1.61.61.70.80.2
Seeking ratio, delayed vs. immediate footshock0.10.10.8-0.9-0.1-0.30.2-0.4-0.0-0.00.0-0.30.2-0.3
Locomotion in novel chamber3.03.77.7-0.7-0.4-1.1-1.2-2.82.22.6-2.6-2.5-2.2-0.8
Locomotion in novel chamber post-restriction1.82.24.4-0.80.0-0.5-0.6-2.11.82.0-2.0-2.1-1.5-0.4
Progressive ratio2.63.06.0-1.7-2.2-1.9-1.61.1-2.4-1.61.61.7-0.3-1.9
Food seeking constrained by brief footshock0.20.30.50.40.50.50.70.70.0-0.50.50.30.70.5
Seeking ratio, punishment vs. effort2.32.96.11.42.21.81.8-0.82.51.5-1.5-1.70.51.9
Run reversals in cocaine runway, females0.90.91.8-1.3-1.2-1.3-0.90.7-0.9-0.70.70.6-0.5-1.3
Run reversals in cocaine runway, males0.70.61.41.01.01.00.7-0.11.20.5-0.5-0.6-0.01.1
Latency to leave start box in cocaine runway0.80.82.2-1.5-1.1-1.2-1.1-0.5-0.40.0-0.0-0.2-1.0-1.3
Latency to leave start box in cocaine runway, F0.10.20.7-0.9-0.3-0.3-0.2-0.3-0.5-0.10.10.0-0.1-0.6
Latency to leave start box in cocaine runway, M0.60.61.4-0.8-1.2-1.2-1.1-0.10.0-0.00.0-0.2-1.0-0.9
Cd content in liver0.70.81.70.40.50.30.0-1.31.11.2-1.2-1.2-0.80.3
Co content in liver3.03.58.01.82.82.22.4-0.62.01.3-1.3-1.31.32.2
Cu content in liver0.20.20.9-0.10.20.20.40.3-0.9-0.50.50.60.7-0.1
Fe content in liver0.10.10.40.1-0.6-0.4-0.50.4-0.4-0.30.30.4-0.4-0.3
K content in liver1.91.93.6-1.4-1.9-1.4-1.41.0-1.7-1.31.31.2-0.5-1.5
Mg content in liver1.31.33.1-1.8-1.5-1.5-1.3-0.1-1.0-0.20.20.2-1.0-1.7
Mn content in liver1.31.53.60.2-0.8-0.1-0.41.4-1.9-1.81.81.70.3-0.3
Na content in liver0.60.71.60.3-0.50.0-0.21.1-1.1-1.11.11.30.30.0
Rb content in liver1.11.42.4-1.1-0.2-0.7-0.5-1.51.11.5-1.5-1.5-1.5-0.8
Se content in liver0.40.41.0-0.6-0.9-0.8-1.0-0.6-0.60.1-0.1-0.1-0.6-0.9
Sr content in liver2.92.73.81.51.01.51.31.8-1.4-1.91.92.01.91.3
Zn content in liver0.70.82.6-0.0-0.00.10.20.9-1.6-1.21.21.30.8-0.1