Hub : Genes

Capn1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000020935 0.24 0.09 0.0e+00 0.14 0.18 0.17 0.16 6.0e-15 2.1e-19 1.3e-18 5.9e-18
2 Adipose intron excision ratio chr1:203299476:203300103 0.03 0.02 5.0e-03 0.01 0.01 0 0.01 6.9e-02 3.4e-02 9.0e-02 6.5e-02
3 Adipose mRNA stability ENSRNOG00000020935 0.17 0.07 1.1e-15 0.1 0.13 0.14 0.13 1.1e-10 5.8e-14 1.6e-15 1.3e-14
4 BLA gene expression ENSRNOG00000020935 0.25 0.13 1.1e-07 0.11 0.12 0.15 0.12 1.2e-06 3.3e-07 1.3e-08 6.6e-07
5 Brain gene expression ENSRNOG00000020935 0.44 0.14 5.6e-17 0.11 0.18 0.19 0.18 1.3e-10 7.8e-17 5.3e-17 6.1e-17
6 Brain intron excision ratio chr1:203299476:203300340 0.07 0.04 3.5e-05 0.04 0.05 0.04 0.04 3.4e-04 1.5e-05 2.4e-04 3.3e-04
7 Brain mRNA stability ENSRNOG00000020935 0.1 0.05 1.5e-05 0.05 0.06 0.06 0.06 1.1e-05 2.3e-06 3.3e-06 2.7e-06
8 Liver gene expression ENSRNOG00000020935 0.08 0.04 2.6e-06 0.01 0.04 0.03 0.02 5.3e-02 7.8e-05 2.3e-04 8.7e-04
9 Liver mRNA stability ENSRNOG00000020935 0.13 0.06 1.1e-09 0.08 0.08 0.09 0.09 1.2e-09 1.5e-09 6.4e-10 9.4e-10
10 NAcc gene expression ENSRNOG00000020935 0.44 0.15 0.0e+00 0.2 0.21 0.21 0.22 4.2e-15 1.6e-15 1.9e-15 1.3e-16
11 PL gene expression ENSRNOG00000020935 0.26 0.13 1.7e-08 0.1 0.09 0.08 0.1 3.6e-08 2.7e-07 1.1e-06 8.6e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail3.511.431.02.30.6-3.4-4.0-4.33.4-3.2-2.9-0.5-3.4-5.6
BMI without tail1.43.08.21.20.6-2.1-2.0-2.01.5-2.1-1.1-0.6-1.4-2.9
Body weight0.93.816.8-0.72.9-0.2-2.2-2.20.9-0.4-0.92.1-0.9-4.1
Epididymis fat weight1.22.77.92.2-2.8-1.1-0.1-1.51.4-1.1-1.2-2.2-2.1-0.1
Glucose2.13.35.52.3-2.3-1.8-0.7-1.81.7-1.8-1.4-2.2-2.1-0.9
Heart weight1.21.86.01.7-2.1-1.10.8-0.60.3-1.60.1-2.4-1.00.4
Left kidney weight0.20.62.31.0-1.5-0.10.7-0.30.8-0.1-0.9-0.8-1.00.5
Right kidney weight0.20.51.4-0.1-0.70.81.00.10.61.2-0.90.6-0.50.6
Tail length1.44.26.6-2.62.42.31.51.6-2.41.82.21.92.30.9
Length with tail1.24.310.4-2.83.22.60.30.7-1.72.11.43.11.6-0.7
Length without tail0.81.75.3-1.62.11.5-0.4-0.4-0.51.20.32.30.3-1.4
Liver weight, left0.10.10.20.3-0.30.10.4-0.40.3-0.2-0.2-0.3-0.4-0.4
Liver weight, right0.30.41.20.3-0.00.30.9-1.1-0.3-0.60.6-0.5-0.7-1.1
Parametrial fat weight2.65.08.32.9-2.8-2.2-1.2-2.22.3-2.0-2.0-2.6-2.6-0.9
Retroperitoneal fat weight2.06.621.03.5-4.6-1.60.2-1.81.9-2.0-1.5-3.8-2.90.5
Intraocular pressure0.50.72.9-0.5-0.80.7-0.10.7-0.01.7-0.40.60.01.6
Extensor digitorum longus weight1.45.521.3-2.34.60.6-2.0-1.00.10.8-0.43.70.5-3.7
Soleus weight0.92.710.12.2-3.2-0.70.5-0.60.5-1.3-0.2-2.9-1.41.0
Tibialis anterior weight3.010.333.6-4.25.83.0-1.2-0.1-1.22.90.65.61.5-2.9
Tibia length0.82.27.9-1.41.11.8-0.9-0.20.72.5-1.42.8-0.4-0.5
Number of licking bursts0.10.10.5-0.20.3-0.0-0.70.00.30.3-0.40.50.1-0.1
Food consumed during 24 hour testing period0.70.92.5-1.00.41.60.60.9-0.41.40.11.10.71.1
Times rat made contact with spout0.20.31.0-0.40.8-0.40.10.7-0.4-0.30.50.11.00.2
Mean time between licks in bursts0.71.03.3-0.91.40.30.40.6-1.5-0.21.80.21.1-0.4
Mean num. licks in bursts0.20.30.70.1-0.1-0.30.90.5-0.5-0.50.6-0.70.50.5
Std. dev. time between licks in bursts0.60.73.3-0.40.60.10.40.5-1.5-0.41.8-0.50.7-0.0
Water consumed over 24 hours1.01.22.7-1.21.30.80.61.5-0.90.70.81.01.60.9
Indifference point 0 sec0.00.00.10.3-0.3-0.10.2-0.10.2-0.2-0.2-0.3-0.20.0
Indifference point AUC1.11.34.7-1.51.80.40.10.7-0.11.5-0.42.21.0-0.3
Indifference point function ln k2.33.313.22.2-2.8-0.91.1-0.4-0.3-2.31.0-3.6-1.00.9
Indifference point function log k2.33.313.22.2-2.8-0.91.1-0.4-0.3-2.31.0-3.6-1.00.9
Delay discounting total patch changes 0 sec0.00.10.2-0.20.10.20.50.2-0.40.00.4-0.10.20.2
Delay discounting total patch changes 12 sec0.81.14.1-1.22.0-0.1-0.70.20.10.7-0.41.90.8-1.0
Delay discounting total patch changes 18 sec0.20.30.7-0.10.4-0.7-0.5-0.40.70.2-0.80.6-0.2-0.7
Delay discounting total patch changes 24 sec1.11.43.6-1.71.91.00.60.6-0.81.30.51.91.0-0.3
Delay discounting total patch changes 6 sec0.10.20.9-0.31.00.0-0.1-0.3-0.1-0.20.10.50.2-0.9
Delay discounting time to switch 0 sec1.72.65.30.90.3-1.1-2.3-1.92.1-0.8-2.10.4-1.6-2.3
Delay discounting water rate 0 sec1.32.06.0-0.2-1.30.92.11.4-1.50.81.6-0.90.92.5
Delay discounting water rate 12 sec2.53.88.10.1-1.70.82.61.8-2.4-0.12.8-2.21.32.8
Delay discounting water rate 18 sec0.81.03.00.6-1.20.31.10.1-1.1-0.81.5-1.70.10.8
Delay discounting water rate 24 sec0.81.12.40.3-1.30.31.40.6-1.3-0.01.5-1.40.51.3
Delay discounting water rate 6 sec1.21.75.20.1-1.10.41.41.1-1.9-0.32.3-1.60.71.5
Locomotor activity0.81.23.9-0.1-0.60.31.30.9-1.7-0.22.0-1.10.91.3
Locomotor testing distance1.32.27.0-0.1-0.60.32.01.2-2.2-0.42.6-1.61.11.4
Locomotor testing rearing1.01.53.80.2-0.80.22.00.9-1.5-0.61.9-1.60.91.2
Light reinforcement 10.20.41.2-0.4-0.00.40.71.0-0.70.30.7-0.10.81.1
Light reinforcement 20.50.61.60.4-1.30.70.1-0.50.90.9-1.10.1-1.00.6
Reaction time number correct0.40.61.1-1.01.01.00.40.4-0.90.90.80.90.60.0
Reaction time mean minus median0.91.14.5-0.81.30.3-0.6-0.40.91.1-1.42.1-0.3-0.9
Reaction time mean minus median AUC0.60.83.4-1.01.20.7-0.20.10.21.2-0.61.80.1-0.3
Reaction time num false alarms0.50.62.70.10.10.10.60.3-1.2-0.91.6-1.00.50.2
Reaction time num false alarms AUC0.40.52.4-0.30.60.10.30.3-1.2-0.81.6-0.50.7-0.1
Reaction time trials correct on left0.40.61.1-1.01.01.00.40.4-0.90.90.80.90.60.0
Reaction time trials on left0.50.71.3-1.21.11.10.40.5-0.90.90.81.10.60.0
Reaction time mean0.20.20.9-0.1-0.1-0.20.20.20.60.7-1.00.7-0.10.5
Reaction time mean AUC0.20.31.40.1-0.3-0.50.10.10.90.5-1.20.5-0.30.5
Median of all reaction times0.20.20.90.2-0.5-0.50.20.20.70.3-0.90.1-0.20.6
Reaction time omissions0.20.31.3-0.71.1-0.20.10.20.00.5-0.21.10.4-0.2
Reaction time false alarm rate0.30.41.30.4-0.1-0.20.1-0.1-0.7-1.21.1-1.10.2-0.1
Reaction time premature initiation rate1.72.26.2-1.72.50.90.71.1-1.90.32.01.21.8-0.5
Reaction time premature initiations2.94.110.3-2.53.21.51.01.7-2.41.02.32.02.4-0.2
Std. dev. reaction times0.30.52.1-0.60.60.2-0.00.10.61.0-1.01.4-0.10.1
Reaction time trials completed0.50.71.3-1.21.11.10.40.5-0.90.90.81.10.60.0
Reaction time trials AUC0.40.50.9-0.90.90.90.40.4-0.90.70.80.80.5-0.0
Social response proportion0.30.31.1-0.60.80.3-0.6-0.00.20.6-0.41.10.1-0.4
Social responses0.40.51.8-0.90.81.3-0.20.3-0.70.70.60.80.60.1
Social time0.50.71.6-1.01.11.30.10.4-0.90.70.90.80.7-0.0
Conditioned locomotion0.50.62.0-1.01.40.9-0.2-0.2-0.50.50.41.20.3-0.9
Cocaine response after cond. corrected0.60.72.60.9-0.9-0.30.7-0.6-0.4-1.20.8-1.6-0.4-0.1
Cocaine response after cond. not corrected0.50.62.10.8-0.8-0.30.6-0.6-0.3-1.10.6-1.4-0.6-0.3
Cocaine response before conditioning0.20.31.0-0.50.60.2-0.30.30.30.7-0.61.00.0-0.1
Saline control response1.01.35.4-1.42.30.9-0.50.0-0.70.40.71.70.6-1.4
Condit. Reinf. active minus inactive responses0.30.41.20.6-0.8-0.5-0.2-0.41.00.1-1.1-0.0-0.80.0
Condit. Reinf. active-inactive response ratio1.61.73.71.2-1.6-0.9-1.0-1.41.7-0.0-1.9-0.3-1.9-0.6
Condit. Reinf. active responses0.10.20.80.4-0.3-0.7-0.2-0.10.8-0.1-0.90.0-0.30.0
Condit. Reinf. inactive responses0.20.20.7-0.10.6-0.30.20.6-0.3-0.60.4-0.20.90.1
Condit. Reinf. lever presses0.60.93.2-0.71.00.3-0.8-0.50.81.1-1.21.8-0.4-0.9
Condit. Reinf. lever reinforcers received0.10.20.7-0.00.1-0.4-0.20.10.60.3-0.90.5-0.00.1
Pavlov. Cond. lever latency0.30.51.00.2-0.3-0.30.60.8-0.8-0.61.0-0.90.70.8
Pavlov. Cond. magazine entry latency0.60.72.1-0.61.4-0.5-1.00.00.50.2-0.71.30.2-1.0
Pavlov. Cond. change in total contacts0.81.24.2-0.30.5-0.6-1.2-0.21.51.0-2.01.7-0.5-0.5
Pavlov. Cond. index score0.70.92.4-0.40.9-0.2-1.1-0.51.10.7-1.41.5-0.4-1.0
Pavlov. Cond. latency score0.70.91.9-0.30.7-0.3-1.2-0.71.10.5-1.41.3-0.6-1.1
Pavlov. Cond. lever contacts0.40.51.8-0.70.61.0-0.1-0.20.21.2-0.51.3-0.2-0.2
Pavlov. Cond. magazine entry number1.11.45.21.2-2.00.30.9-0.2-0.6-0.91.1-2.3-0.50.9
Pavlov. Cond. intertrial magazine entries0.20.31.20.7-1.10.2-0.1-0.50.2-0.3-0.1-0.9-0.60.3
Pavlov. Cond. lever-magazine prob. diff.0.70.92.7-0.61.1-0.1-1.1-0.41.00.7-1.31.7-0.2-1.0
Pavlov. Cond. response bias0.50.73.0-0.81.10.4-0.5-0.10.51.1-0.91.7-0.0-0.5
Conditioned reinforcement - actives0.30.31.2-0.2-0.50.40.1-0.20.41.1-0.70.6-0.50.4
Conditioned reinforcement - inactives1.31.56.81.0-2.6-0.10.40.60.70.5-0.9-1.2-0.62.2
Conditioned locomotion1.41.77.30.9-2.7-0.21.40.40.00.5-0.1-1.6-0.42.4
Intermittent access intake day 1-15 change0.50.51.9-0.5-0.60.60.60.6-0.21.4-0.10.50.21.3
Intermittent access intake escalation0.30.31.0-0.1-0.70.20.40.30.10.9-0.30.2-0.01.0
Intermittent access intake escalation 20.70.72.2-0.7-0.10.50.71.0-0.31.5-0.10.90.61.2
Intermitt. access day 1 inactive lever presses0.70.72.91.0-1.7-0.20.4-0.10.6-0.3-0.6-1.2-0.51.1
Intermitt. access day 15 inactive lever presses0.80.93.70.9-1.90.20.0-0.30.90.3-1.1-0.8-0.81.2
Intermitt. access escalation Index2.11.96.61.9-1.8-1.40.3-0.60.6-2.1-0.1-2.6-0.90.2
Intermittent access day 1 total infusions6.06.711.93.3-3.5-2.4-1.3-2.52.6-2.3-2.2-3.1-3.2-0.8
Intermittent access day 15 total infusions3.33.712.62.4-3.5-1.3-0.2-1.41.8-0.7-1.7-2.3-2.40.8
Intermittent access terminal intake (last 3 days)3.43.810.32.3-3.2-1.2-0.8-1.82.1-0.6-2.1-1.9-2.70.1
Intermittent access total infusions4.34.710.12.7-3.2-1.9-1.2-2.12.4-1.3-2.2-2.3-2.8-0.3
Intermittent access day 1 locomotion5.55.79.83.1-2.8-2.4-1.1-2.52.0-2.7-1.5-3.1-2.7-1.1
Intermittent access day 15 total locomotion2.42.57.91.9-2.8-1.50.2-1.11.6-0.6-1.5-1.8-1.80.7
Intermittent access total locomotion6.27.014.03.3-3.7-2.5-1.3-2.62.9-1.8-2.6-2.8-3.3-0.4
Intermittent access standard deviation0.20.31.10.1-1.00.20.20.10.10.7-0.3-0.2-0.21.0
Cocaine induced anxiety0.10.10.4-0.2-0.00.5-0.3-0.30.20.6-0.40.5-0.4-0.1
Post-drug Anxiety0.91.03.7-1.21.11.3-0.2-0.3-0.11.6-0.21.90.1-0.6
Baseline Anxiety1.01.03.1-1.41.81.0-0.10.3-0.80.80.71.50.8-0.6
Lifetime Intake4.24.78.92.7-3.0-2.1-1.3-2.12.2-1.6-2.0-2.5-2.8-0.6
Incentive Sensitization - Responses0.50.51.20.7-1.1-0.5-0.3-0.60.90.0-1.0-0.4-0.90.1
Incentive Sensitization - Breakpoint0.50.51.60.8-1.3-0.5-0.2-0.50.90.1-1.0-0.4-0.90.3
Progressive ratio test 1 active lever presses0.80.83.61.1-1.9-0.6-0.1-0.20.6-0.3-0.6-1.3-0.80.8
Progressive ratio test 1 breakpoint0.60.62.90.9-1.7-0.30.00.00.4-0.1-0.4-1.1-0.70.9
Progressive ratio test 1 inactive lever presses0.50.51.70.9-1.2-0.6-0.10.20.2-0.7-0.1-1.3-0.20.8
Progressive ratio test 2 active lever presses1.71.86.71.6-2.6-0.9-0.2-0.71.3-0.2-1.4-1.4-1.60.8
Progressive ratio test 2 breakpoint1.31.56.91.4-2.6-0.60.3-0.20.80.0-0.9-1.5-1.21.4
Progressive ratio test 2 inactive lever presses3.13.613.52.4-3.7-1.40.0-0.91.8-0.6-1.8-2.4-1.91.5
Total sessions with >9 infusions2.32.54.22.0-1.8-1.5-1.1-1.71.2-1.8-0.7-2.1-1.9-0.9
Short access day 1 total inactive lever presses1.61.85.21.8-2.3-1.5-0.4-0.60.8-1.3-0.5-2.2-1.00.6
Short access day 10 total inactive lever presses1.11.24.31.1-1.6-0.60.70.3-0.4-1.20.7-2.10.01.4
Short access day 1 total infusions3.84.16.92.6-2.5-2.1-1.4-1.81.9-2.2-1.5-2.6-2.1-0.7
Short access day 10 total infusions5.86.39.03.0-2.5-2.6-2.0-2.82.6-2.5-2.2-2.5-3.0-1.7
Short access total infusions3.33.65.42.3-2.0-2.0-1.3-2.11.7-2.0-1.3-2.2-2.3-1.2
Short access day 1 locomotion3.23.46.02.4-2.2-2.1-0.9-1.81.5-2.1-1.0-2.4-2.1-0.7
Short access day 10 total locomotion2.83.05.22.2-2.0-2.1-0.9-1.61.5-1.9-1.2-2.3-1.8-0.6
Short access total locomotion2.82.85.02.1-1.8-2.1-0.6-1.61.4-2.0-1.0-2.2-1.8-0.8
Compulsive drug intake2.92.95.7-1.82.41.41.21.9-2.00.42.11.22.40.3
One hour access (0.3 mA shock)2.63.112.92.1-3.6-1.10.1-0.71.1-0.5-1.0-2.5-1.91.5
One hour access (shock baseline)3.33.814.32.2-3.8-1.4-0.5-1.11.90.0-2.1-1.9-2.41.2
Number of responses in last shaping day0.40.41.10.2-0.7-0.31.10.5-0.6-0.20.8-0.90.31.0
Context. condit. distance diff. score0.70.82.81.2-1.4-0.20.7-0.50.2-1.10.1-1.7-0.60.3
Locomotion velocity, session 10.30.31.0-0.40.50.21.00.1-0.9-0.11.0-0.10.4-0.2
Locomotion distance, session 10.70.92.90.70.3-1.1-0.9-1.20.6-1.4-0.3-0.6-0.7-1.7
Locomotion velocity, session 20.80.93.4-0.21.3-0.4-1.7-0.80.4-0.4-0.40.7-0.2-1.8
Locomotion distance, session 20.50.72.10.40.6-1.0-1.1-0.90.3-1.2-0.1-0.4-0.3-1.4
Locomotion velocity, session 31.51.73.11.4-0.8-1.1-0.5-1.81.0-1.6-0.6-1.3-1.6-1.7
Locomotion distance, session 30.10.10.40.3-0.2-0.20.6-0.40.0-0.30.1-0.4-0.3-0.2
Stereotopy head waving bouts, day 31.62.04.21.6-1.0-1.0-0.5-2.00.8-1.8-0.3-1.6-1.7-1.8
Stereotopy head waving duration, day 30.70.91.51.2-1.0-0.7-0.7-1.20.7-1.1-0.4-1.2-1.2-0.8
Locomotion velocity, session 72.83.14.62.1-1.5-2.0-0.8-2.11.8-2.1-1.4-1.8-1.9-1.4
Locomotion distance, session 70.81.02.91.1-0.5-1.10.2-1.30.5-1.7-0.1-1.3-0.8-1.0
Stereotopy head waving bouts, day 70.50.61.70.8-0.9-0.8-0.6-0.61.2-0.1-1.3-0.2-0.9-0.3
Stereotopy head waving duration, day 70.50.61.70.20.3-0.7-1.3-0.31.10.1-1.30.7-0.5-0.8
Locomotion velocity, session 80.70.92.1-1.11.51.20.20.2-1.20.31.30.80.7-0.7
Locomotion distance, session 81.01.43.41.4-0.9-0.7-0.5-1.81.0-1.4-0.7-1.2-1.5-1.4
Degree of sensitization distance1.01.12.31.1-0.5-0.8-0.9-1.50.8-1.3-0.4-0.9-1.1-1.4
Degree of sensitization stereotypy0.40.41.80.10.0-0.4-0.7-0.11.10.5-1.30.7-0.4-0.3
Condit. Reinf. active minus inactive responses0.10.10.30.20.2-0.5-0.4-0.10.2-0.5-0.1-0.10.1-0.3
Condit. Reinf. active-inactive response ratio0.10.20.7-0.20.2-0.30.10.8-0.2-0.00.10.00.70.6
Condit. Reinf. active responses0.40.51.20.7-0.3-0.7-1.1-0.80.8-0.6-0.7-0.4-0.7-0.7
Condit. Reinf. inactive responses1.31.53.01.2-0.9-0.8-1.4-1.71.3-0.8-1.2-0.6-1.7-1.4
Incentive salience index mean0.50.61.60.60.1-0.9-1.3-0.80.7-0.9-0.5-0.4-0.5-1.1
Condit. Reinf. lever presses0.60.82.40.40.1-0.2-1.5-1.20.9-0.4-0.80.1-1.1-1.5
Time in familiar zone, hab. session 10.50.50.80.9-0.8-0.6-0.4-0.80.7-0.8-0.5-0.8-0.8-0.5
Time in novel zone, hab. session 10.80.81.9-0.60.40.61.40.7-1.30.21.4-0.10.90.8
Total zone transitions, hab. session 10.10.10.4-0.20.6-0.5-0.5-0.00.3-0.1-0.30.40.2-0.3
Total locomotion distance, hab. session 10.81.11.81.3-1.0-1.1-0.5-1.31.0-1.1-0.9-1.1-1.2-0.8
Locomotion velocity, hab. session 10.50.71.00.9-0.5-0.9-0.8-1.00.9-0.8-0.7-0.6-0.9-0.8
Time in familiar zone, hab. session 20.60.62.6-0.50.60.80.70.3-1.3-0.21.6-0.20.6-0.2
Time in novel zone, hab. session 20.40.41.40.4-0.3-1.2-0.6-0.10.9-0.2-1.10.0-0.20.0
Total zone transitions, hab. session 21.41.84.40.90.5-1.8-1.6-1.61.2-1.5-1.0-0.3-1.0-2.1
Total locomotion distance, hab. session 21.82.44.01.6-0.7-1.8-1.3-2.01.3-2.0-0.9-1.4-1.5-1.8
Locomotion velocity, hab. session 22.12.95.01.8-1.0-1.9-1.5-2.21.6-1.9-1.3-1.4-1.8-1.9
Novel to familiar place preference ratio0.60.62.2-0.30.3-0.5-0.8-0.21.10.8-1.51.2-0.3-0.2
Novelty place preference0.40.41.9-0.10.0-0.6-0.6-0.11.00.6-1.40.8-0.20.1
Time in novel zone, NPP test0.30.31.4-0.00.0-0.5-0.5-0.10.90.5-1.20.7-0.20.0
Total zone transitions, NPP test0.50.82.4-0.21.2-0.5-1.4-0.80.6-0.3-0.70.8-0.3-1.6
Total locomotion distance, NPP test0.70.91.60.9-0.2-1.1-1.0-1.20.9-1.3-0.6-0.7-0.9-1.3
Locomotion velocity, NPP test0.50.81.30.8-0.2-1.1-1.1-1.00.9-1.1-0.7-0.6-0.7-1.0
Pavlov. Cond. lever latency0.40.51.7-0.3-0.20.21.30.8-0.70.40.6-0.10.71.1
Pavlov. Cond. magazine entry latency0.70.81.60.8-0.2-1.2-1.2-0.81.3-0.8-1.3-0.3-0.7-0.8
Pavlov. Cond. change in total contacts0.60.72.40.6-0.5-1.0-1.1-0.31.3-0.0-1.50.1-0.6-0.1
Pavlov. Cond. index score0.10.20.80.10.1-0.1-0.9-0.20.50.1-0.70.3-0.2-0.2
Pavlov. Cond. latency score0.20.31.20.3-0.0-0.2-1.1-0.50.6-0.3-0.6-0.0-0.4-0.5
Pavlov. Cond. lever contacts0.20.20.60.4-0.1-0.2-0.8-0.60.4-0.5-0.3-0.3-0.4-0.7
Pavlov. Cond. magazine entry number0.20.30.80.4-0.3-0.20.5-0.4-0.4-0.80.7-0.9-0.3-0.5
Pavlov. Cond. intertrial magazine entries0.30.31.8-0.1-0.70.10.50.9-0.10.7-0.0-0.00.31.3
Pavlov. Cond. lever-magazine prob. diff.0.20.21.10.00.2-0.2-1.0-0.30.60.1-0.80.4-0.2-0.4
Pavlov. Cond. response bias0.10.10.3-0.10.1-0.0-0.40.10.40.3-0.50.40.10.2
Bone: apparent density1.11.93.41.2-0.3-0.9-1.7-1.71.7-1.2-1.5-0.4-1.5-1.8
Bone surface1.52.76.8-0.31.3-0.0-2.1-1.71.80.5-2.11.9-1.4-2.6
Bone volume1.32.25.50.60.2-0.5-1.8-1.72.10.0-2.30.9-1.7-2.0
Bone: connectivity density1.01.64.70.40.8-0.6-1.8-1.61.4-0.6-1.40.6-1.1-2.2
Bone: cortical apparent density0.60.82.3-0.70.7-0.80.61.4-0.60.30.50.41.51.0
Bone: cortical area0.30.41.2-0.50.71.0-0.5-0.30.30.8-0.51.1-0.4-0.7
Bone: cortical porosity0.30.31.10.5-0.1-0.7-1.1-0.30.6-0.6-0.6-0.2-0.5-0.6
Bone: cortical porosity0.20.21.10.00.5-0.3-1.0-0.20.3-0.3-0.30.2-0.2-0.7
Bone: cortical thickness1.72.86.2-2.22.51.80.41.4-1.61.31.42.01.90.2
Bone: cortical thickness1.51.73.5-1.31.51.01.91.1-1.70.41.80.61.60.6
Bone: cortical tissue density0.70.92.7-0.90.9-0.70.71.5-0.70.40.60.61.61.1
Bone: elastic displacement1.51.64.3-0.60.01.21.81.3-1.90.22.1-0.51.21.3
Bone: elastic work1.11.53.3-1.31.51.11.30.8-1.70.21.80.61.30.0
Bone: endosteal estimation2.45.211.42.5-2.2-1.5-1.2-3.12.4-1.7-2.0-1.8-3.4-2.2
Bone: endosteal perimeter2.65.412.82.5-2.5-1.2-1.1-2.92.8-1.1-2.7-1.5-3.6-1.9
Bone: final force0.71.23.4-0.81.60.7-0.9-0.90.50.5-0.71.7-0.4-1.9
Bone: final moment0.61.13.1-0.71.50.7-1.0-0.80.50.5-0.61.6-0.4-1.8
Bone: marrow area2.55.411.42.6-2.2-1.6-1.3-3.12.4-1.9-2.0-1.9-3.4-2.3
Bone: maximum diameter0.50.81.6-0.20.01.0-0.5-0.90.91.1-1.21.1-1.3-0.9
Bone: maximum force1.52.58.10.11.1-0.3-1.7-2.11.8-0.1-1.91.4-1.5-2.9
Bone: maximum moment1.32.37.40.21.0-0.2-1.7-2.01.7-0.2-1.81.2-1.5-2.7
Bone: minimum diameter2.54.77.52.6-2.1-2.1-1.3-2.32.5-2.0-2.2-2.0-2.7-1.6
Bone: periosteal estimation1.02.15.71.1-0.9-0.2-0.9-2.11.7-0.3-1.7-0.2-2.4-1.8
Bone: periosteal perimeter0.61.02.60.5-0.40.1-0.7-1.31.30.1-1.40.3-1.6-1.3
Bone: post-yield work8.411.420.33.1-1.7-3.2-3.7-4.04.5-2.1-4.4-1.0-4.0-3.5
Bone: stiffness1.22.04.60.20.8-0.5-1.7-1.61.8-0.0-2.01.2-1.3-2.2
Bone: tissue strength0.10.10.40.1-0.2-0.0-0.5-0.20.50.2-0.70.3-0.3-0.1
Bone: trabecular number1.01.53.40.8-0.3-0.5-1.5-1.61.7-0.3-1.80.3-1.5-1.4
Bone: trabecular spacing0.40.51.3-0.10.1-0.70.80.8-0.9-0.51.1-0.70.80.6
Bone: trabecular thickness0.80.91.61.3-1.3-0.4-1.0-0.71.2-0.9-1.1-1.0-1.0-0.2
Bone: trabecular tissue density0.60.83.60.9-1.9-0.20.80.30.1-0.0-0.0-1.3-0.41.4
Breakpoint value in progressive ratio session0.80.93.5-1.11.50.8-0.90.30.21.0-0.51.90.4-0.7
Distance traveled before self-admin0.40.41.2-0.30.40.2-1.1-0.30.60.7-0.81.0-0.2-0.4
Distance traveled after self-admin0.30.31.1-0.40.30.4-1.10.60.20.7-0.40.80.40.2
Delta time in closed arm before/after self-admin0.60.62.5-0.10.60.2-0.6-0.2-1.2-1.01.6-0.60.4-0.6
Delta time in open arm before/after self-admin0.60.51.7-0.5-0.00.70.00.80.41.3-0.81.00.30.8
Diff in mean of infusions in LGA sessions0.50.51.1-1.00.80.9-0.20.5-0.60.90.41.00.70.4
Extinction: sum of active levers before priming0.80.82.2-0.51.5-0.1-1.2-0.20.70.1-0.91.30.1-1.3
Active lever presses in extinction session 61.91.85.4-1.71.61.8-1.10.2-0.32.0-0.12.30.4-0.4
Delta distance traveled before/after self-admin0.20.20.6-0.20.10.40.10.7-0.6-0.10.8-0.20.60.3
Delta ambulatory time before/after self-admin0.30.31.1-0.30.40.40.20.8-0.9-0.21.0-0.20.80.3
Time in closed arm before self-admin0.30.31.20.2-0.30.0-0.5-0.50.90.4-1.10.4-0.8-0.3
Time in closed arm after self-admin0.30.41.00.5-0.2-0.3-1.0-0.70.0-0.90.3-0.7-0.5-0.6
Time in open arm before self-admin1.31.43.30.3-0.0-1.11.80.6-1.3-1.51.7-1.51.00.5
Time in open arm after self-admin0.91.02.7-0.70.20.41.61.4-1.00.50.80.11.21.4
Sum of active levers in priming session hrs 5-62.52.58.4-1.91.21.9-0.80.8-0.32.9-0.42.80.60.6
Time to tail flick, vehicle, before self-admin0.60.61.50.30.2-0.8-0.1-1.20.9-0.3-0.80.2-0.9-1.2
Time to tail flick, vehicle, after self-admin0.80.94.10.30.9-0.7-0.9-1.30.3-1.20.0-0.1-0.6-2.0
Time to tail flick, test, before self-admin2.32.34.41.8-1.2-1.8-0.5-1.81.0-2.1-0.5-1.9-1.5-1.3
Time to tail flick, test, after self-admin0.10.10.5-0.40.3-0.20.70.3-0.30.40.30.30.30.1
Delta time to tail flick, vehicle, before/after SA0.20.20.90.10.6-0.1-0.8-0.4-0.1-0.70.3-0.1-0.0-0.9
Delta time to tail flick, test, before/after SA4.23.76.6-2.41.81.81.32.2-1.62.61.02.42.01.5
Ambulatory time before self-admin0.60.61.6-0.20.10.5-1.2-0.30.91.0-1.21.1-0.5-0.3
Ambulatory time after self-admin0.60.62.60.6-0.8-0.3-1.6-0.11.10.1-1.3-0.0-0.50.1
Total heroin consumption1.21.45.5-1.52.40.3-0.40.4-0.20.9-0.12.20.9-1.0
Area under the delay curve0.50.52.00.9-0.4-1.4-0.0-0.20.5-1.3-0.3-1.0-0.2-0.3
Delay disc. indifference point, 0s delay1.01.13.01.2-0.6-1.70.6-0.60.4-1.7-0.0-1.7-0.5-0.5
Delay disc. indifference point, 16s delay0.90.92.61.2-1.3-1.6-0.4-0.31.0-0.8-0.9-1.1-0.60.6
Delay disc. indifference point, 2s delay0.20.30.50.6-0.5-0.70.3-0.50.5-0.5-0.4-0.6-0.6-0.4
Delay disc. indifference point, 24s delay0.40.41.0-0.20.3-0.40.50.6-0.8-0.41.0-0.40.90.5
Delay disc. indifference point, 4s delay0.50.52.00.7-0.2-0.90.0-0.0-0.1-1.40.4-1.30.1-0.3
Delay disc. indifference point, 8s delay0.30.31.20.40.0-0.60.40.0-0.2-1.10.4-0.90.1-0.2
Delay discount exponential model param0.40.41.6-0.70.21.3-0.10.0-0.31.10.10.90.10.2
Delay discount hyperbolic model param0.30.31.4-0.60.21.2-0.30.0-0.31.00.10.80.00.2
Fecal boli incidents, locomotor time 10.50.62.20.1-0.40.2-0.4-0.41.11.0-1.50.9-0.9-0.0
Change in fecal boli incidents, locomotor task0.70.62.20.50.2-0.1-0.6-0.8-0.4-1.50.9-1.0-0.2-1.2
Time >=10cm from walls, locomotor time 14.24.38.52.1-1.9-1.5-2.2-2.62.5-1.0-2.5-1.0-2.9-1.5
Bouts of movement, locomotor time 11.51.64.1-1.51.30.20.22.0-0.61.30.11.61.91.3
Total resting periods, locomotor time 10.91.02.4-1.10.9-0.1-0.21.6-0.21.1-0.31.41.41.1
Rest time, locomotor task time 10.20.20.70.1-0.90.4-0.50.1-0.30.40.2-0.5-0.20.7
Distance moved, locomotor task time 10.50.61.00.8-0.2-1.0-0.1-1.00.8-1.0-0.6-0.5-0.8-0.9
Vertical activity count, locomotor time 10.40.41.20.7-1.1-0.51.00.00.1-0.50.0-1.0-0.40.6
Time >=10cm from walls, locomotor time 20.30.31.10.1-0.2-0.2-0.9-0.10.80.4-1.10.4-0.40.1
Bouts of movement, locomotor time 20.40.41.4-0.60.7-0.00.51.2-0.20.3-0.00.71.20.7
Total resting periods, locomotor time 20.20.20.8-0.20.3-0.30.20.90.10.1-0.20.40.80.6
Rest time, locomotor task time 20.80.92.81.3-1.7-0.4-0.9-0.50.6-0.8-0.4-1.6-0.90.1
Distance moved, locomotor task time 20.50.51.5-1.01.20.30.80.6-0.50.70.31.10.60.0
Vertical activity count, locomotor time 21.31.43.2-1.20.81.01.41.1-1.80.71.80.51.10.9
Weight adjusted by age0.70.83.2-1.21.40.5-0.7-0.0-0.11.1-0.11.80.4-0.7
Seeking ratio, delayed vs. immediate footshock0.30.41.30.8-0.5-1.20.1-0.10.5-1.0-0.4-0.7-0.2-0.0
Locomotion in novel chamber1.31.66.81.4-2.6-0.2-0.1-0.81.10.1-1.2-1.3-1.70.9
Locomotion in novel chamber post-restriction0.80.93.71.2-1.9-0.40.5-0.20.6-0.4-0.5-1.4-0.91.0
Progressive ratio2.42.76.80.90.4-1.2-2.6-2.11.8-1.1-1.80.2-1.5-2.5
Food seeking constrained by brief footshock0.20.31.1-0.40.70.6-0.00.3-0.9-0.21.00.10.5-0.1
Seeking ratio, punishment vs. effort2.22.76.6-0.6-0.30.92.62.0-2.10.32.3-0.81.62.2
Run reversals in cocaine runway, females1.81.85.61.20.1-1.7-1.3-1.50.6-2.4-0.1-1.3-0.8-1.9
Run reversals in cocaine runway, males1.21.12.3-0.90.21.51.41.0-1.31.11.20.50.81.0
Latency to leave start box in cocaine runway1.01.11.51.2-0.8-0.8-1.0-1.21.2-1.1-1.1-0.8-1.1-1.0
Latency to leave start box in cocaine runway, F0.30.30.80.6-0.4-0.9-0.0-0.10.8-0.6-0.8-0.4-0.3-0.1
Latency to leave start box in cocaine runway, M0.90.82.40.6-0.40.3-1.5-1.50.5-0.5-0.3-0.3-1.1-1.3
Cd content in liver0.50.61.9-0.1-1.00.91.10.40.11.1-0.30.2-0.01.4
Co content in liver2.42.86.2-0.7-0.00.62.12.4-2.00.22.1-0.72.12.5
Cu content in liver0.10.10.40.10.3-0.4-0.60.30.3-0.2-0.40.00.30.1
Fe content in liver0.10.10.4-0.30.30.20.0-0.50.10.5-0.10.6-0.4-0.5
K content in liver1.31.34.60.60.5-0.8-1.1-1.51.1-1.0-0.9-0.0-1.2-2.2
Mg content in liver2.02.14.01.5-0.6-2.0-1.2-1.41.6-1.8-1.3-1.1-1.3-1.5
Mn content in liver0.70.83.2-0.91.20.4-0.7-0.30.41.1-0.81.8-0.0-0.8
Na content in liver0.50.61.8-0.91.01.0-0.30.0-0.11.0-0.11.40.0-0.6
Rb content in liver1.11.43.61.6-1.6-1.30.9-0.50.8-1.6-0.5-1.9-0.80.1
Se content in liver0.60.72.50.3-0.7-0.1-1.1-0.51.30.7-1.60.5-1.0-0.1
Sr content in liver2.82.55.6-2.12.01.70.11.6-1.11.90.62.41.60.5
Zn content in liver0.20.20.6-0.30.8-0.3-0.80.10.30.0-0.40.60.3-0.4