Ccnd1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000088588 0.06 0.08 6.0e-03 0.01 0.01 0.01 0.01 6.8e-02 3.2e-02 6.5e-02 1.2e-02
2 Adipose alternative polyA ENSRNOT00000108193 0.1 0.12 3.5e-03 0.01 0.01 0.01 0.03 8.1e-03 2.1e-02 8.7e-03 4.8e-04
3 Adipose gene expression ENSRNOG00000020918 0.03 0.02 3.7e-03 0.02 0.02 0.01 0.01 6.4e-03 2.6e-03 2.2e-02 1.4e-02
4 BLA gene expression ENSRNOG00000020918 0.16 0.07 4.7e-08 0.13 0.13 0.14 0.12 2.3e-07 1.8e-07 9.7e-08 4.1e-07
5 Liver gene expression ENSRNOG00000020918 0.03 0.02 1.3e-03 0 0.02 0 0 2.1e-01 3.6e-03 2.8e-01 8.2e-02
6 NAcc alternative polyA ENSRNOT00000088588 0.27 0.14 4.7e-05 0.04 0.05 0.04 0.03 6.7e-04 1.2e-04 2.7e-04 4.2e-03
7 NAcc alternative polyA ENSRNOT00000108193 0.31 0.15 3.9e-05 0.04 0.06 0.04 0.03 1.1e-03 5.6e-05 2.8e-04 5.1e-03
8 OFC gene expression ENSRNOG00000020918 0.64 0.13 1.6e-10 0.28 0.28 0.34 0.31 1.7e-07 2.3e-07 7.5e-09 4.5e-08
9 PL alternative polyA ENSRNOT00000088588 0.05 0.03 2.6e-03 0.03 0.03 0.02 0.03 2.4e-03 4.3e-03 7.3e-03 1.7e-03
10 PL alternative polyA ENSRNOT00000108193 0.04 0.03 4.0e-03 0.03 0.02 0.02 0.03 4.2e-03 7.3e-03 1.1e-02 4.7e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail1.65.19.51.9-2.00.50.2-2.82.9-2.80.83.1-3.1
BMI without tail0.81.83.91.4-1.50.50.2-2.01.2-1.10.81.7-1.7
Body weight0.73.010.40.2-0.5-1.51.9-1.31.5-1.43.21.9-1.9
Epididymis fat weight1.43.211.50.9-0.42.3-3.40.2-1.11.1-3.2-0.90.9
Glucose1.72.75.71.5-1.41.9-2.1-1.21.6-1.7-2.41.0-1.0
Heart weight0.50.82.60.8-0.71.3-1.6-0.30.1-0.1-1.60.0-0.0
Left kidney weight0.61.84.3-0.20.41.0-1.40.8-2.02.1-1.3-1.51.5
Right kidney weight0.92.55.6-1.01.30.3-0.91.5-2.42.4-0.7-2.02.0
Tail length0.82.36.4-1.21.0-1.82.11.0-1.41.52.5-0.90.9
Length with tail0.93.414.7-1.41.1-2.72.90.7-0.40.43.8-0.10.1
Length without tail0.71.65.9-1.00.8-1.91.70.30.6-0.72.40.6-0.6
Liver weight, left0.20.30.70.5-0.30.7-0.9-0.1-0.70.8-0.6-0.40.4
Liver weight, right0.40.61.4-0.10.30.4-0.90.6-1.21.1-0.5-0.90.9
Parametrial fat weight0.91.74.51.4-1.22.1-2.0-0.90.00.0-2.10.1-0.1
Retroperitoneal fat weight1.85.919.31.1-0.53.1-4.40.4-1.61.5-4.4-1.41.4
Intraocular pressure0.70.92.1-1.11.2-0.60.11.4-0.50.4-0.4-1.41.4
Extensor digitorum longus weight1.66.328.0-1.61.2-3.54.00.00.10.05.31.3-1.3
Soleus weight1.44.18.9-0.71.01.1-1.51.6-2.93.0-2.1-2.42.4
Tibialis anterior weight2.69.131.8-2.72.5-4.24.01.5-2.12.25.6-0.50.5
Tibia length0.41.22.7-0.70.8-0.70.11.2-1.61.60.7-1.31.3
Number of licking bursts0.20.20.50.6-0.70.5-0.1-0.6-0.10.2-0.10.5-0.5
Food consumed during 24 hour testing period0.30.40.90.3-0.20.6-0.80.2-0.90.9-0.7-0.60.6
Times rat made contact with spout0.80.91.71.2-1.30.50.2-1.30.8-0.80.21.2-1.2
Mean time between licks in bursts0.40.62.2-0.20.0-1.01.5-0.10.4-0.41.50.4-0.4
Mean num. licks in bursts0.10.20.50.3-0.40.10.0-0.40.7-0.7-0.00.4-0.4
Std. dev. time between licks in bursts1.41.63.0-1.31.2-1.51.71.2-1.00.91.6-1.11.1
Water consumed over 24 hours0.70.81.81.2-1.30.30.1-1.20.4-0.30.61.2-1.2
Indifference point 0 sec0.00.00.20.1-0.20.4-0.3-0.30.0-0.0-0.10.2-0.2
Indifference point AUC0.40.52.1-0.30.1-0.71.20.1-0.60.71.4-0.10.1
Indifference point function ln k0.81.14.50.10.11.1-1.50.6-0.70.7-2.1-1.01.0
Indifference point function log k0.81.14.50.10.11.1-1.50.6-0.70.7-2.1-1.01.0
Delay discounting total patch changes 0 sec0.10.10.2-0.30.2-0.20.40.1-0.40.40.5-0.20.2
Delay discounting total patch changes 12 sec0.91.14.1-0.90.6-1.41.5-0.10.7-0.72.00.7-0.7
Delay discounting total patch changes 18 sec0.20.30.70.4-0.50.00.4-0.70.00.10.80.8-0.8
Delay discounting total patch changes 24 sec0.70.83.60.1-0.3-0.51.3-0.3-1.11.21.9-0.00.0
Delay discounting total patch changes 6 sec0.60.91.70.8-1.00.10.4-1.21.0-1.00.81.3-1.3
Delay discounting time to switch 0 sec1.42.14.70.9-0.80.2-0.1-1.72.0-1.90.32.2-2.2
Delay discounting water rate 0 sec2.54.08.6-1.01.10.1-0.42.1-2.92.8-0.9-2.82.8
Delay discounting water rate 12 sec3.75.510.1-0.91.10.8-1.62.3-3.23.1-2.2-3.23.2
Delay discounting water rate 18 sec0.91.22.20.10.00.9-1.00.6-1.51.5-1.1-1.41.4
Delay discounting water rate 24 sec2.43.35.9-1.51.7-0.4-0.22.2-2.32.2-0.7-2.42.4
Delay discounting water rate 6 sec1.72.55.8-0.91.0-0.2-0.21.7-2.42.3-0.2-2.12.1
Locomotor activity0.91.43.70.20.01.1-1.50.4-1.91.9-0.9-1.01.0
Locomotor testing distance0.81.32.8-0.20.40.7-1.20.7-1.71.7-1.0-1.31.3
Locomotor testing rearing0.81.23.81.1-0.91.6-1.8-0.5-0.10.1-2.00.0-0.0
Light reinforcement 10.20.41.4-0.30.30.3-0.70.6-0.30.2-1.2-0.60.6
Light reinforcement 20.81.13.1-0.20.31.0-1.40.7-1.01.0-1.7-1.11.1
Reaction time number correct0.10.20.4-0.20.2-0.5-0.10.60.5-0.70.1-0.40.4
Reaction time mean minus median0.60.71.70.4-0.5-0.20.2-0.81.2-1.10.51.3-1.3
Reaction time mean minus median AUC0.20.30.50.2-0.3-0.40.3-0.30.7-0.70.60.7-0.7
Reaction time num false alarms0.91.23.1-0.80.7-0.81.10.9-1.71.80.9-1.01.0
Reaction time num false alarms AUC0.81.12.6-0.70.5-1.11.60.6-1.21.31.6-0.50.5
Reaction time trials correct on left0.10.20.4-0.20.2-0.5-0.10.60.5-0.70.1-0.40.4
Reaction time trials on left0.10.20.4-0.30.3-0.6-0.00.60.5-0.60.2-0.40.4
Reaction time mean0.30.40.80.6-0.50.5-0.6-0.50.6-0.6-0.50.9-0.9
Reaction time mean AUC0.40.50.80.8-0.60.6-0.8-0.60.5-0.5-0.60.9-0.9
Median of all reaction times0.40.50.80.7-0.50.6-0.7-0.50.7-0.7-0.70.9-0.9
Reaction time omissions0.30.51.3-0.30.2-0.91.0-0.20.7-0.71.20.5-0.5
Reaction time false alarm rate0.81.22.9-0.80.6-0.81.50.5-1.61.71.3-0.50.5
Reaction time premature initiation rate1.21.63.5-1.21.1-1.91.40.41.4-1.61.60.3-0.3
Reaction time premature initiations1.41.95.0-1.41.3-2.21.60.81.4-1.61.8-0.00.0
Std. dev. reaction times0.30.40.90.4-0.50.00.1-0.50.8-0.80.11.0-1.0
Reaction time trials completed0.10.20.4-0.30.3-0.6-0.00.60.5-0.60.2-0.40.4
Reaction time trials AUC0.10.10.4-0.10.1-0.5-0.10.50.5-0.60.1-0.40.4
Social response proportion1.31.45.90.0-0.2-0.40.6-0.52.3-2.40.11.0-1.0
Social responses0.10.20.4-0.40.3-0.50.60.20.3-0.30.60.2-0.2
Social time0.20.30.6-0.30.2-0.50.7-0.10.8-0.80.50.5-0.5
Conditioned locomotion2.12.54.7-2.01.8-2.22.01.5-0.60.62.0-1.01.0
Cocaine response after cond. corrected0.10.10.30.5-0.60.5-0.1-0.3-0.10.1-0.30.2-0.2
Cocaine response after cond. not corrected0.70.81.91.3-1.41.1-0.6-1.00.2-0.1-0.70.6-0.6
Cocaine response before conditioning0.60.71.51.2-1.21.0-0.7-1.00.3-0.2-0.50.7-0.7
Saline control response0.71.02.90.2-0.4-0.91.3-0.61.0-1.01.70.9-0.9
Condit. Reinf. active minus inactive responses2.02.43.71.9-1.91.9-1.6-1.51.3-1.3-1.61.2-1.2
Condit. Reinf. active-inactive response ratio1.51.64.31.2-1.01.9-2.0-0.70.4-0.4-2.10.4-0.4
Condit. Reinf. active responses2.23.15.81.7-1.91.3-0.9-1.82.3-2.4-1.11.7-1.7
Condit. Reinf. inactive responses1.41.84.80.9-1.2-0.00.4-1.32.1-2.20.41.5-1.5
Condit. Reinf. lever presses1.41.94.21.9-2.01.1-0.3-1.90.9-0.80.01.6-1.6
Condit. Reinf. lever reinforcers received2.33.26.51.8-1.91.2-0.7-1.92.5-2.5-0.81.8-1.8
Pavlov. Cond. lever latency0.40.61.0-1.01.0-1.00.50.80.8-1.00.2-0.30.3
Pavlov. Cond. magazine entry latency1.82.14.31.0-1.2-0.00.8-1.71.6-1.51.02.1-2.1
Pavlov. Cond. change in total contacts0.81.12.21.4-1.50.9-0.2-1.40.6-0.5-0.11.3-1.3
Pavlov. Cond. index score0.60.81.71.1-1.20.6-0.0-1.30.5-0.40.31.3-1.3
Pavlov. Cond. latency score0.50.71.51.1-1.10.7-0.2-1.20.2-0.10.21.1-1.1
Pavlov. Cond. lever contacts0.30.51.40.8-0.80.7-0.2-0.4-1.11.2-0.1-0.20.2
Pavlov. Cond. magazine entry number2.12.65.3-1.31.4-0.1-0.51.9-1.91.8-1.0-2.32.3
Pavlov. Cond. intertrial magazine entries0.30.41.2-0.50.6-0.1-0.10.9-0.30.2-0.6-1.11.1
Pavlov. Cond. lever-magazine prob. diff.0.70.91.91.1-1.20.40.2-1.30.7-0.60.51.4-1.4
Pavlov. Cond. response bias0.50.71.71.2-1.30.60.1-1.20.2-0.10.31.0-1.0
Conditioned reinforcement - actives0.70.72.2-1.41.5-0.6-0.11.2-0.60.5-0.0-0.60.6
Conditioned reinforcement - inactives1.92.25.40.7-0.41.9-2.10.2-1.51.5-2.3-1.31.3
Conditioned locomotion3.23.96.9-0.50.91.3-2.21.6-2.52.4-2.6-2.12.1
Intermittent access intake day 1-15 change1.01.04.0-0.00.10.7-0.40.4-1.92.0-0.7-0.80.8
Intermittent access intake escalation0.70.72.10.2-0.00.9-0.60.2-1.41.5-0.9-0.60.6
Intermittent access intake escalation 20.40.40.9-0.30.40.1-0.10.6-0.90.9-0.6-0.90.9
Intermitt. access day 1 inactive lever presses0.60.61.30.4-0.31.1-1.1-0.1-0.70.7-1.1-0.80.8
Intermitt. access day 15 inactive lever presses0.91.02.31.0-0.81.5-1.2-0.4-1.01.1-1.5-0.30.3
Intermitt. access escalation Index1.00.91.70.10.00.8-0.70.5-1.21.3-1.3-1.11.1
Intermittent access day 1 total infusions3.64.18.32.5-2.42.9-2.6-2.00.9-0.9-2.51.0-1.0
Intermittent access day 15 total infusions3.13.59.01.8-1.53.0-2.7-0.9-1.31.4-2.9-0.40.4
Intermittent access terminal intake (last 3 days)2.42.67.01.7-1.52.6-2.3-1.0-0.70.8-2.5-0.10.1
Intermittent access total infusions2.02.25.91.8-1.72.4-2.0-1.3-0.20.3-2.10.2-0.2
Intermittent access day 1 locomotion2.12.13.71.8-1.71.9-1.5-1.71.0-1.0-1.41.0-1.0
Intermittent access day 15 total locomotion1.81.95.31.2-1.12.2-2.2-0.5-0.50.5-2.3-0.20.2
Intermittent access total locomotion3.33.79.62.1-1.93.1-2.9-1.5-0.00.1-2.90.2-0.2
Intermittent access standard deviation0.40.40.90.1-0.10.7-0.70.1-0.70.7-0.7-0.90.9
Cocaine induced anxiety0.10.10.30.1-0.00.2-0.1-0.1-0.40.5-0.2-0.10.1
Post-drug Anxiety0.91.02.2-1.41.3-1.51.20.8-0.10.01.2-0.30.3
Baseline Anxiety1.31.43.3-1.31.1-1.81.70.60.8-0.81.80.1-0.1
Lifetime Intake1.51.74.51.5-1.42.1-1.8-1.2-0.00.1-1.80.2-0.2
Incentive Sensitization - Responses0.10.10.50.1-0.00.3-0.60.10.1-0.2-0.7-0.20.2
Incentive Sensitization - Breakpoint0.20.20.80.2-0.10.5-0.70.1-0.10.0-0.9-0.30.3
Progressive ratio test 1 active lever presses0.60.61.30.3-0.30.9-0.70.1-1.11.1-0.9-0.80.8
Progressive ratio test 1 breakpoint0.50.51.30.2-0.10.7-0.50.3-1.11.1-0.7-0.90.9
Progressive ratio test 1 inactive lever presses0.30.30.60.00.00.7-0.7-0.1-0.70.8-0.5-0.50.5
Progressive ratio test 2 active lever presses0.90.93.10.4-0.21.2-1.60.2-0.60.6-1.8-0.80.8
Progressive ratio test 2 breakpoint1.21.33.10.00.21.1-1.50.7-1.31.3-1.7-1.21.2
Progressive ratio test 2 inactive lever presses3.03.58.71.5-1.12.8-3.0-0.4-1.51.5-2.9-0.80.8
Total sessions with >9 infusions0.40.41.20.6-0.61.1-0.9-0.5-0.50.6-0.6-0.00.0
Short access day 1 total inactive lever presses0.91.02.80.9-0.71.7-1.5-0.4-0.70.8-1.6-0.20.2
Short access day 10 total inactive lever presses0.91.03.10.8-0.71.5-1.8-0.3-0.80.8-1.3-0.50.5
Short access day 1 total infusions0.90.92.90.8-0.61.6-1.7-0.70.2-0.2-1.60.1-0.1
Short access day 10 total infusions2.93.25.42.2-2.32.0-1.2-2.21.5-1.5-1.31.6-1.6
Short access total infusions0.80.91.91.2-1.21.4-0.9-1.30.4-0.3-0.80.8-0.8
Short access day 1 locomotion1.31.43.21.5-1.41.8-1.4-1.20.10.0-1.30.9-0.9
Short access day 10 total locomotion1.01.01.61.0-1.01.1-1.1-1.01.2-1.3-1.10.6-0.6
Short access total locomotion0.60.61.00.7-0.71.0-0.8-0.90.8-0.8-0.70.7-0.7
Compulsive drug intake2.32.35.6-1.81.6-2.42.11.00.3-0.32.3-0.30.3
One hour access (0.3 mA shock)2.73.18.71.1-0.82.5-2.9-0.1-1.31.3-3.0-1.01.0
One hour access (shock baseline)3.03.511.41.0-0.62.5-3.10.2-1.21.2-3.4-1.31.3
Number of responses in last shaping day0.40.41.0-0.10.20.4-0.60.4-1.01.0-0.4-0.80.8
Context. condit. distance diff. score0.20.31.3-0.20.30.4-0.90.10.5-0.5-1.1-0.00.0
Locomotion velocity, session 10.10.10.20.1-0.10.2-0.2-0.20.4-0.5-0.10.3-0.3
Locomotion distance, session 11.52.03.41.6-1.61.3-1.0-1.91.0-0.9-0.31.8-1.8
Locomotion velocity, session 20.70.83.50.2-0.4-0.61.4-0.6-0.40.51.90.8-0.8
Locomotion distance, session 20.71.02.21.4-1.40.9-0.3-1.50.10.00.31.2-1.2
Locomotion velocity, session 31.72.03.61.8-1.91.5-0.8-1.90.8-0.7-0.41.6-1.6
Locomotion distance, session 30.10.10.30.2-0.10.2-0.4-0.30.5-0.5-0.20.3-0.3
Stereotopy head waving bouts, day 31.21.52.61.6-1.61.5-0.9-1.60.5-0.4-0.71.2-1.2
Stereotopy head waving duration, day 31.11.43.01.6-1.51.7-1.5-1.20.2-0.1-1.30.6-0.6
Locomotion velocity, session 70.60.71.30.7-0.70.5-0.4-1.01.0-0.9-0.01.1-1.1
Locomotion distance, session 70.20.20.8-0.10.1-0.30.0-0.20.8-0.90.40.5-0.5
Stereotopy head waving bouts, day 71.61.82.71.5-1.41.6-1.6-1.31.1-1.1-1.41.1-1.1
Stereotopy head waving duration, day 71.82.23.51.5-1.60.9-0.4-1.81.8-1.80.01.9-1.9
Locomotion velocity, session 80.50.62.20.1-0.3-0.71.1-0.50.6-0.61.50.8-0.8
Locomotion distance, session 80.40.61.40.9-0.71.2-1.2-0.7-0.20.3-0.80.4-0.4
Degree of sensitization distance0.30.30.60.3-0.4-0.10.2-0.50.8-0.80.30.6-0.6
Degree of sensitization stereotypy0.91.01.90.8-0.80.7-0.7-1.01.3-1.4-0.41.2-1.2
Condit. Reinf. active minus inactive responses0.50.60.80.8-0.80.8-0.7-0.80.6-0.6-0.40.9-0.9
Condit. Reinf. active-inactive response ratio0.40.41.30.7-0.50.8-1.1-0.50.2-0.2-0.70.6-0.6
Condit. Reinf. active responses0.10.10.30.4-0.30.5-0.5-0.4-0.20.2-0.30.3-0.3
Condit. Reinf. inactive responses0.10.10.4-0.20.10.00.30.1-0.60.60.2-0.40.4
Incentive salience index mean0.40.50.80.9-0.80.9-0.7-0.9-0.00.1-0.20.8-0.8
Condit. Reinf. lever presses0.20.21.20.0-0.00.30.0-0.0-1.01.10.2-0.10.1
Time in familiar zone, hab. session 11.31.22.71.4-1.41.6-1.1-1.0-0.91.1-0.90.3-0.3
Time in novel zone, hab. session 10.60.61.3-1.11.0-1.10.80.70.7-0.80.5-0.20.2
Total zone transitions, hab. session 10.50.71.61.2-1.11.0-1.0-1.0-0.30.4-0.10.6-0.6
Total locomotion distance, hab. session 10.91.33.51.1-0.81.6-1.9-0.5-1.11.2-1.3-0.10.1
Locomotion velocity, hab. session 10.50.72.00.8-0.51.2-1.4-0.3-0.91.0-1.0-0.10.1
Time in familiar zone, hab. session 20.70.71.5-1.00.9-1.21.20.8-0.20.10.9-0.60.6
Time in novel zone, hab. session 20.90.91.41.1-1.10.9-0.6-1.20.9-0.8-0.51.2-1.2
Total zone transitions, hab. session 24.05.29.02.8-2.91.8-0.9-3.01.9-1.8-0.12.8-2.8
Total locomotion distance, hab. session 21.21.52.61.6-1.51.4-1.0-1.60.7-0.6-0.71.4-1.4
Locomotion velocity, hab. session 21.31.73.01.7-1.61.7-1.4-1.60.4-0.3-1.11.2-1.2
Novel to familiar place preference ratio0.60.62.00.4-0.5-0.00.1-0.61.4-1.40.00.8-0.8
Novelty place preference0.60.61.80.6-0.60.3-0.3-0.71.3-1.3-0.20.8-0.8
Time in novel zone, NPP test0.70.72.00.6-0.70.3-0.3-0.71.4-1.4-0.20.8-0.8
Total zone transitions, NPP test1.21.83.71.7-1.81.0-0.2-1.90.5-0.40.51.7-1.7
Total locomotion distance, NPP test0.50.71.21.1-1.11.1-0.5-1.1-0.40.6-0.30.8-0.8
Locomotion velocity, NPP test0.40.61.11.0-0.91.0-0.4-0.9-0.70.9-0.30.5-0.5
Pavlov. Cond. lever latency0.50.61.4-1.21.2-0.80.30.90.5-0.6-0.3-0.60.6
Pavlov. Cond. magazine entry latency1.01.21.81.1-1.21.0-0.6-1.31.2-1.2-0.51.3-1.3
Pavlov. Cond. change in total contacts0.70.81.81.2-1.21.4-0.9-1.0-0.20.3-0.80.5-0.5
Pavlov. Cond. index score0.30.40.90.8-0.80.9-0.6-0.5-0.60.6-0.40.2-0.2
Pavlov. Cond. latency score0.30.40.90.9-0.90.9-0.6-0.7-0.30.4-0.30.4-0.4
Pavlov. Cond. lever contacts0.50.51.21.1-1.10.9-0.4-0.8-0.60.7-0.00.5-0.5
Pavlov. Cond. magazine entry number0.00.00.1-0.10.1-0.20.3-0.00.00.00.30.1-0.1
Pavlov. Cond. intertrial magazine entries0.70.82.7-0.40.3-0.00.40.6-1.61.60.1-1.01.0
Pavlov. Cond. lever-magazine prob. diff.0.30.40.80.8-0.80.9-0.6-0.6-0.60.7-0.20.2-0.2
Pavlov. Cond. response bias0.20.30.60.8-0.70.8-0.5-0.5-0.50.6-0.30.2-0.2
Bone: apparent density3.45.612.13.4-3.52.4-1.3-3.21.1-1.0-0.62.5-2.5
Bone surface3.35.911.43.2-3.41.8-0.8-3.21.7-1.50.23.0-3.0
Bone volume2.94.911.23.3-3.42.3-1.2-3.00.8-0.6-0.42.3-2.3
Bone: connectivity density3.55.48.92.7-2.91.4-0.5-3.02.3-2.20.13.0-3.0
Bone: cortical apparent density0.91.13.0-1.41.2-1.51.70.60.5-0.51.3-0.10.1
Bone: cortical area0.81.25.40.3-0.30.00.7-0.0-2.12.31.0-0.50.5
Bone: cortical porosity0.10.10.40.2-0.10.3-0.6-0.20.4-0.5-0.40.2-0.2
Bone: cortical porosity0.10.10.3-0.10.2-0.30.0-0.00.5-0.50.20.3-0.3
Bone: cortical thickness2.03.37.8-1.51.3-2.12.61.1-1.92.12.8-0.90.9
Bone: cortical thickness0.70.92.5-0.90.7-1.31.60.5-0.50.51.6-0.20.2
Bone: cortical tissue density1.01.33.5-1.51.3-1.71.90.70.6-0.61.4-0.10.1
Bone: elastic displacement2.42.74.4-1.81.9-1.20.42.1-1.81.70.4-2.12.1
Bone: elastic work1.11.42.5-1.11.1-1.41.21.0-1.31.31.6-0.80.8
Bone: endosteal estimation1.94.19.02.9-2.73.0-2.4-1.9-0.81.0-1.90.8-0.8
Bone: endosteal perimeter2.85.712.73.2-3.03.6-3.1-2.20.10.0-2.91.1-1.1
Bone: final force0.71.12.31.1-1.30.11.0-1.3-0.20.41.51.2-1.2
Bone: final moment0.61.12.01.2-1.30.20.9-1.3-0.50.71.41.1-1.1
Bone: marrow area1.94.19.02.9-2.73.0-2.5-1.9-0.91.1-1.90.8-0.8
Bone: maximum diameter0.81.45.61.0-1.01.1-0.5-0.4-2.22.4-0.2-0.40.4
Bone: maximum force2.13.77.72.7-2.81.4-0.2-2.80.5-0.30.72.4-2.4
Bone: maximum moment1.93.47.32.6-2.71.5-0.3-2.60.20.10.62.2-2.2
Bone: minimum diameter2.64.910.43.2-3.23.1-2.0-2.5-0.30.6-1.71.5-1.5
Bone: periosteal estimation1.12.25.11.9-1.81.8-0.9-1.1-2.02.2-0.40.1-0.1
Bone: periosteal perimeter0.81.33.41.8-1.91.5-0.7-1.3-0.50.6-0.50.6-0.6
Bone: post-yield work7.810.618.44.3-4.23.8-2.7-4.11.7-1.5-2.03.4-3.4
Bone: stiffness2.33.77.92.6-2.81.5-0.2-2.70.6-0.40.42.3-2.3
Bone: tissue strength1.61.63.21.6-1.51.8-1.3-1.1-1.21.4-1.00.3-0.3
Bone: trabecular number2.84.38.42.8-2.91.9-1.0-2.71.5-1.4-0.52.3-2.3
Bone: trabecular spacing1.01.32.4-1.51.5-1.00.51.4-1.01.00.5-1.31.3
Bone: trabecular thickness2.42.96.32.5-2.52.3-1.5-2.00.3-0.2-1.31.3-1.3
Bone: trabecular tissue density2.63.79.4-0.81.00.7-0.91.6-3.03.1-1.5-2.32.3
Breakpoint value in progressive ratio session0.70.82.7-0.30.1-0.81.4-0.50.6-0.61.61.0-1.0
Distance traveled before self-admin0.20.20.4-0.20.40.2-0.6-0.20.4-0.4-0.10.7-0.7
Distance traveled after self-admin0.20.20.30.3-0.30.6-0.6-0.5-0.40.5-0.10.5-0.5
Delta time in closed arm before/after self-admin1.01.01.7-1.21.2-1.31.20.8-0.70.71.3-0.20.2
Delta time in open arm before/after self-admin0.30.30.70.7-0.70.8-0.7-0.50.2-0.2-0.70.1-0.1
Diff in mean of infusions in LGA sessions0.50.51.2-1.11.1-1.00.70.60.5-0.60.60.2-0.2
Extinction: sum of active levers before priming0.90.92.40.0-0.2-0.61.0-0.90.8-0.71.51.3-1.3
Active lever presses in extinction session 61.21.22.5-1.21.2-1.21.10.8-1.01.01.6-0.80.8
Delta distance traveled before/after self-admin0.10.10.20.4-0.50.30.0-0.3-0.40.5-0.00.0-0.0
Delta ambulatory time before/after self-admin0.10.10.30.3-0.50.00.5-0.2-0.50.50.4-0.10.1
Time in closed arm before self-admin0.10.10.30.4-0.50.40.1-0.40.4-0.3-0.50.0-0.0
Time in closed arm after self-admin0.40.41.1-0.50.3-0.51.00.3-0.80.80.8-0.30.3
Time in open arm before self-admin0.30.41.1-0.91.0-0.80.00.7-0.0-0.10.5-0.40.4
Time in open arm after self-admin0.20.20.5-0.60.7-0.2-0.50.50.1-0.2-0.1-0.60.6
Sum of active levers in priming session hrs 5-62.42.44.0-1.71.7-1.10.71.7-2.02.01.0-1.51.5
Time to tail flick, vehicle, before self-admin3.03.15.61.7-1.90.9-0.1-2.02.0-2.00.02.4-2.4
Time to tail flick, vehicle, after self-admin1.01.01.80.4-0.7-0.61.0-0.91.3-1.41.21.2-1.2
Time to tail flick, test, before self-admin2.02.03.31.6-1.71.5-0.7-1.81.0-0.9-0.61.7-1.7
Time to tail flick, test, after self-admin0.20.20.80.4-0.6-0.20.9-0.30.1-0.00.50.2-0.2
Delta time to tail flick, vehicle, before/after SA0.20.20.9-0.10.0-0.60.70.0-0.20.31.0-0.10.1
Delta time to tail flick, test, before/after SA2.92.65.5-1.61.3-2.12.31.7-1.21.21.8-1.31.3
Ambulatory time before self-admin0.30.30.8-0.30.50.3-0.9-0.30.5-0.6-0.20.7-0.7
Ambulatory time after self-admin1.11.22.51.1-1.01.6-1.6-1.20.4-0.3-1.21.0-1.0
Total heroin consumption1.61.95.6-1.21.0-1.92.10.11.1-1.22.40.7-0.7
Area under the delay curve1.01.11.61.2-1.20.9-0.9-1.21.1-1.2-0.60.9-0.9
Delay disc. indifference point, 0s delay2.22.43.11.6-1.61.3-1.4-1.71.7-1.8-0.91.7-1.7
Delay disc. indifference point, 16s delay0.80.93.00.9-0.71.3-1.7-0.3-0.20.2-1.5-0.40.4
Delay disc. indifference point, 2s delay0.70.81.51.2-1.11.1-1.1-0.90.6-0.6-0.80.7-0.7
Delay disc. indifference point, 24s delay0.30.30.6-0.50.5-0.70.50.6-0.30.30.6-0.80.8
Delay disc. indifference point, 4s delay0.50.61.60.6-0.70.4-0.3-0.71.2-1.3-0.20.7-0.7
Delay disc. indifference point, 8s delay0.30.30.90.5-0.50.2-0.3-0.60.9-0.9-0.00.5-0.5
Delay discount exponential model param0.70.81.2-1.11.1-0.70.71.0-1.01.10.4-0.70.7
Delay discount hyperbolic model param0.80.81.2-1.11.1-0.80.71.0-1.11.10.4-0.80.8
Fecal boli incidents, locomotor time 10.30.30.70.8-0.80.8-0.5-0.5-0.50.5-0.30.3-0.3
Change in fecal boli incidents, locomotor task0.40.41.0-0.40.3-0.70.8-0.11.0-1.00.40.4-0.4
Time >=10cm from walls, locomotor time 12.93.05.72.4-2.32.4-1.4-2.10.00.2-1.41.5-1.5
Bouts of movement, locomotor time 11.01.13.0-1.10.9-1.61.70.80.2-0.31.5-0.40.4
Total resting periods, locomotor time 10.60.71.7-0.90.7-1.31.30.80.1-0.11.1-0.40.4
Rest time, locomotor task time 11.21.32.8-0.70.80.0-0.51.3-1.31.3-0.9-1.71.7
Distance moved, locomotor task time 11.01.12.10.8-0.80.6-0.3-1.11.4-1.4-0.31.3-1.3
Vertical activity count, locomotor time 10.40.51.80.6-0.40.9-1.0-0.30.5-0.5-1.30.1-0.1
Time >=10cm from walls, locomotor time 20.20.20.4-0.50.5-0.20.10.4-0.60.60.1-0.50.5
Bouts of movement, locomotor time 20.40.41.0-0.70.6-1.00.70.40.5-0.50.8-0.40.4
Total resting periods, locomotor time 20.20.20.4-0.50.4-0.70.50.20.4-0.50.5-0.20.2
Rest time, locomotor task time 21.41.64.11.6-1.51.9-1.7-0.9-0.10.2-2.00.2-0.2
Distance moved, locomotor task time 20.91.02.2-1.41.4-1.51.01.00.3-0.41.2-0.30.3
Vertical activity count, locomotor time 22.32.54.5-2.02.1-1.61.02.0-1.31.21.0-1.61.6
Weight adjusted by age0.80.91.9-1.11.1-1.40.90.41.1-1.21.10.1-0.1
Seeking ratio, delayed vs. immediate footshock0.60.71.40.7-0.80.50.1-1.10.9-0.8-0.01.2-1.2
Locomotion in novel chamber2.22.76.81.7-1.52.6-2.4-0.6-1.01.1-2.6-0.20.2
Locomotion in novel chamber post-restriction1.01.23.60.10.21.1-1.90.5-0.70.7-1.9-1.01.0
Progressive ratio3.64.28.01.7-2.00.60.4-2.62.4-2.30.82.8-2.8
Food seeking constrained by brief footshock0.20.30.6-0.40.3-0.60.6-0.00.7-0.70.60.1-0.1
Seeking ratio, punishment vs. effort2.42.95.7-1.61.8-0.7-0.22.2-1.81.7-0.6-2.42.4
Run reversals in cocaine runway, females1.41.42.70.7-0.90.10.4-1.41.7-1.60.41.6-1.6
Run reversals in cocaine runway, males0.80.81.4-0.70.6-0.70.80.8-1.11.20.8-1.01.0
Latency to leave start box in cocaine runway0.90.91.71.3-1.21.0-0.8-1.10.7-0.6-0.81.0-1.0
Latency to leave start box in cocaine runway, F0.50.50.70.9-0.80.6-0.5-0.80.7-0.7-0.60.8-0.8
Latency to leave start box in cocaine runway, M0.20.20.40.6-0.60.4-0.1-0.3-0.40.40.00.2-0.2
Cd content in liver0.40.51.2-0.20.30.4-0.70.7-0.50.5-1.1-1.01.0
Co content in liver1.11.32.2-1.51.5-0.80.61.4-0.90.9-0.0-1.31.3
Cu content in liver0.20.30.7-0.40.5-0.40.20.3-0.80.90.6-0.30.3
Fe content in liver0.20.20.50.6-0.60.6-0.5-0.4-0.60.70.10.2-0.2
K content in liver1.31.32.81.5-1.50.9-0.4-1.70.7-0.50.21.4-1.4
Mg content in liver2.82.94.62.1-2.01.9-1.7-2.01.3-1.2-1.31.7-1.7
Mn content in liver0.20.30.80.6-0.7-0.10.3-0.70.3-0.20.90.5-0.5
Na content in liver0.30.30.8-0.70.9-0.4-0.30.7-0.50.40.1-0.60.6
Rb content in liver1.62.03.51.4-1.41.7-1.3-1.41.3-1.3-1.91.1-1.1
Se content in liver0.70.92.10.8-0.70.8-1.4-0.71.1-1.1-0.80.7-0.7
Sr content in liver0.90.82.3-1.00.9-1.51.30.60.1-0.21.5-0.20.2
Zn content in liver0.30.30.7-0.40.5-0.60.60.1-0.70.80.80.2-0.2