Hub : Genes

Cspg5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000020833 0.26 0.14 0.0e+00 0.24 0.24 0.23 0.23 6.0e-26 4.6e-26 3.0e-25 8.9e-26
2 Adipose mRNA stability ENSRNOG00000020833 0.04 0.03 1.6e-04 0.04 0.03 0.03 0.03 5.5e-05 1.5e-04 1.0e-04 9.4e-05
3 BLA gene expression ENSRNOG00000020833 0.29 0.25 1.6e-10 0.14 0.18 0.15 0.17 3.4e-08 8.5e-10 2.5e-08 2.0e-09
4 BLA intron excision ratio chr8:110227983:110234131 0.05 0.06 8.8e-03 0.02 0.01 0.01 0.01 3.1e-02 5.2e-02 7.8e-02 5.2e-02
5 BLA intron excision ratio chr8:110228064:110234131 0.06 0.06 5.6e-03 0.02 0.02 0.02 0.02 1.9e-02 2.7e-02 3.9e-02 3.2e-02
6 Brain gene expression ENSRNOG00000020833 0.25 0.18 5.3e-15 0.15 0.16 0.16 0.16 1.1e-13 1.8e-14 2.7e-14 2.1e-14
7 Brain intron excision ratio chr8:110227983:110234131 0.05 0.04 2.3e-04 0.03 0.04 0.02 0.03 1.1e-03 2.0e-04 2.4e-03 1.2e-03
8 Brain intron excision ratio chr8:110228064:110234131 0.05 0.05 9.9e-05 0.03 0.04 0.03 0.03 5.1e-04 7.9e-05 6.3e-04 5.5e-04
9 Brain mRNA stability ENSRNOG00000020833 0.05 0.05 5.4e-04 0.03 0.03 0.04 0.03 4.3e-04 6.8e-04 3.4e-04 7.2e-04
10 IL gene expression ENSRNOG00000020833 0.46 0.22 2.7e-08 0.24 0.24 0.21 0.23 2.2e-06 1.7e-06 9.4e-06 2.4e-06
11 LHb gene expression ENSRNOG00000020833 0.73 0.16 4.9e-11 0.31 0.3 0.32 0.32 4.6e-08 8.2e-08 2.1e-08 3.1e-08
12 Liver gene expression ENSRNOG00000020833 0.18 0.12 1.0e-14 0.13 0.13 0.12 0.13 1.2e-14 3.0e-14 3.5e-13 2.2e-14
13 NAcc gene expression ENSRNOG00000020833 0.19 0.2 9.2e-09 0.1 0.1 0.1 0.09 3.3e-08 8.1e-08 1.6e-07 2.2e-07
14 OFC gene expression ENSRNOG00000020833 0.7 0.19 3.7e-06 0.14 0.14 0.16 0.15 3.2e-04 2.9e-04 1.3e-04 1.9e-04
15 PL gene expression ENSRNOG00000020833 0.59 0.22 3.0e-10 0.13 0.13 0.14 0.13 7.8e-10 5.5e-10 4.6e-11 8.3e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail0.51.75.2-0.6-1.0-0.91.5-1.5-1.31.0-1.0-1.5-1.0-1.5-0.7-1.4-1.4-2.3
BMI without tail1.94.19.8-1.6-1.4-1.92.2-2.2-2.11.9-1.9-1.6-1.9-2.1-1.6-2.3-2.1-3.1
Body weight6.728.237.3-4.9-4.6-5.35.4-5.4-5.45.2-5.2-5.1-5.2-5.4-5.1-5.7-5.4-6.1
Epididymis fat weight0.30.82.5-0.8-1.3-0.80.8-0.8-0.80.8-0.8-1.6-0.8-0.9-0.5-1.1-0.8-0.4
Glucose0.30.51.0-0.6-1.0-0.60.8-0.8-0.70.6-0.6-0.4-0.6-0.8-0.5-0.7-0.7-0.7
Heart weight2.73.86.0-1.8-1.6-1.91.8-1.8-1.91.9-1.9-2.5-1.9-2.0-2.0-1.9-2.0-2.4
Left kidney weight0.92.67.0-1.2-1.1-1.41.9-1.9-1.71.4-1.4-1.1-1.4-1.9-1.2-1.7-1.7-2.6
Right kidney weight0.30.73.2-0.5-0.2-0.71.0-1.0-0.90.7-0.70.1-0.7-1.0-0.4-1.0-0.9-1.8
Tail length6.720.322.3-4.6-4.0-4.74.4-4.4-4.64.7-4.7-3.8-4.7-4.5-4.5-4.7-4.6-4.5
Length with tail9.334.137.0-5.9-5.1-6.15.8-5.8-6.06.0-6.0-5.1-6.0-5.9-6.0-6.1-6.0-5.9
Length without tail6.313.814.6-3.7-3.5-3.83.7-3.7-3.83.8-3.8-3.8-3.8-3.8-3.8-3.7-3.8-3.2
Liver weight, left0.10.10.3-0.5-0.5-0.30.2-0.2-0.20.3-0.30.3-0.3-0.2-0.2-0.2-0.30.5
Liver weight, right1.32.22.6-1.5-1.5-1.51.5-1.5-1.61.5-1.5-1.1-1.5-1.5-1.2-1.6-1.6-1.4
Parametrial fat weight1.22.32.6-1.5-1.4-1.51.6-1.6-1.61.5-1.5-1.1-1.5-1.6-1.4-1.5-1.6-1.6
Retroperitoneal fat weight0.61.94.0-1.4-1.0-1.51.1-1.1-1.41.4-1.4-1.0-1.4-1.4-1.4-1.6-1.5-2.0
Intraocular pressure0.91.32.3-1.4-1.5-1.30.8-0.8-1.01.2-1.2-1.3-1.2-1.0-1.3-1.0-1.1-0.1
Extensor digitorum longus weight0.20.61.60.80.70.8-0.70.70.8-0.80.80.40.80.80.70.70.81.3
Soleus weight4.011.616.3-3.1-3.2-3.33.4-3.4-3.43.3-3.3-3.2-3.3-3.4-3.4-3.5-3.4-4.0
Tibialis anterior weight0.00.00.1-0.1-0.1-0.10.2-0.2-0.20.1-0.1-0.4-0.1-0.1-0.2-0.4-0.1-0.0
Tibia length7.019.929.4-4.0-3.8-4.34.7-4.7-4.64.3-4.3-3.9-4.3-4.6-4.2-4.7-4.6-5.4
Number of licking bursts0.20.31.00.40.20.5-0.60.60.5-0.50.5-0.10.50.60.30.50.61.0
Food consumed during 24 hour testing period1.51.82.7-1.2-1.2-1.31.4-1.4-1.41.3-1.3-1.2-1.3-1.4-1.3-1.3-1.3-1.6
Times rat made contact with spout0.50.60.9-0.8-0.7-0.71.0-1.0-0.80.7-0.7-0.9-0.8-0.9-0.5-0.6-0.7-0.1
Mean time between licks in bursts1.21.61.91.41.11.3-1.41.41.3-1.31.31.21.31.31.11.31.30.8
Mean num. licks in bursts0.70.81.4-0.8-0.6-0.91.2-1.2-1.00.9-0.9-0.3-0.9-1.2-0.6-0.8-1.0-1.0
Std. dev. time between licks in bursts4.25.16.32.32.22.3-2.52.52.4-2.32.31.62.42.51.92.32.41.6
Water consumed over 24 hours0.00.00.10.10.20.10.1-0.1-0.0-0.10.1-0.40.1-0.10.10.10.0-0.0
Indifference point 0 sec1.01.62.3-1.4-0.9-1.31.4-1.4-1.31.3-1.3-0.5-1.3-1.3-1.5-1.2-1.3-0.6
Indifference point AUC0.10.10.4-0.3-0.7-0.30.3-0.3-0.30.3-0.3-0.2-0.3-0.30.0-0.5-0.4-0.3
Indifference point function ln k0.30.41.20.81.10.6-0.60.60.4-0.60.60.90.60.40.30.50.4-0.9
Indifference point function log k0.30.41.20.81.10.6-0.60.60.4-0.60.60.90.60.40.30.50.4-0.9
Delay discounting total patch changes 0 sec1.11.82.7-1.5-1.1-1.41.5-1.5-1.41.4-1.4-0.8-1.4-1.4-1.7-1.3-1.4-0.7
Delay discounting total patch changes 12 sec0.91.21.5-1.2-1.1-1.21.1-1.1-1.11.2-1.2-0.7-1.2-1.1-1.2-1.1-1.1-0.7
Delay discounting total patch changes 18 sec2.22.94.7-1.9-2.2-1.81.6-1.6-1.61.8-1.8-1.6-1.8-1.6-1.8-1.6-1.6-0.5
Delay discounting total patch changes 24 sec3.03.84.5-1.9-2.1-2.01.9-1.9-2.02.0-2.0-1.9-2.0-1.9-2.0-2.0-2.0-1.8
Delay discounting total patch changes 6 sec0.10.20.3-0.6-0.4-0.50.5-0.5-0.50.5-0.5-0.0-0.5-0.5-0.5-0.4-0.50.2
Delay discounting time to switch 0 sec0.10.20.60.40.50.4-0.50.50.5-0.40.40.10.40.50.30.40.50.7
Delay discounting water rate 0 sec0.10.20.3-0.4-0.5-0.40.4-0.4-0.40.4-0.4-0.4-0.4-0.5-0.5-0.1-0.5-0.2
Delay discounting water rate 12 sec0.30.51.7-0.5-0.7-0.60.5-0.5-0.60.6-0.6-0.9-0.6-0.6-0.8-0.7-0.7-1.3
Delay discounting water rate 18 sec0.10.22.30.10.1-0.00.1-0.1-0.20.0-0.0-0.3-0.0-0.2-0.1-0.1-0.3-1.5
Delay discounting water rate 24 sec0.71.01.4-1.0-1.2-1.00.9-0.9-1.01.0-1.0-1.1-1.0-1.0-0.8-0.9-1.0-0.9
Delay discounting water rate 6 sec0.40.63.1-0.5-0.5-0.60.6-0.6-0.70.6-0.6-0.4-0.6-0.7-0.8-0.6-0.8-1.8
Locomotor activity5.58.810.5-3.0-2.5-3.03.0-3.0-3.03.0-3.0-2.5-3.0-2.9-3.1-2.9-3.0-3.2
Locomotor testing distance5.18.511.4-2.9-2.6-3.02.8-2.8-3.03.0-3.0-2.3-3.0-2.8-3.1-3.0-3.0-3.4
Locomotor testing rearing0.10.20.7-0.6-0.5-0.50.2-0.2-0.30.5-0.5-0.3-0.5-0.1-0.8-0.4-0.3-0.3
Light reinforcement 10.81.43.6-1.1-1.0-1.21.0-1.0-1.11.1-1.2-0.9-1.1-1.1-1.0-1.4-1.2-1.9
Light reinforcement 20.20.32.40.40.60.3-0.40.40.2-0.30.30.90.30.20.3-0.10.2-1.6
Reaction time number correct0.40.61.10.71.00.7-1.01.00.8-0.70.70.90.70.80.50.70.80.4
Reaction time mean minus median0.10.10.4-0.1-0.4-0.20.5-0.5-0.30.2-0.2-0.3-0.2-0.30.0-0.3-0.3-0.6
Reaction time mean minus median AUC0.30.41.0-0.4-1.0-0.50.7-0.7-0.60.5-0.5-0.6-0.5-0.5-0.4-0.6-0.6-0.7
Reaction time num false alarms0.40.51.40.51.20.6-0.70.70.7-0.60.61.00.60.70.50.60.70.8
Reaction time num false alarms AUC0.10.20.90.10.90.2-0.30.30.3-0.20.20.80.20.30.10.30.30.4
Reaction time trials correct on left0.40.61.10.71.00.7-1.01.00.8-0.70.70.90.70.80.50.70.80.4
Reaction time trials on left0.50.71.10.71.10.7-1.11.10.9-0.80.80.90.80.90.50.80.90.5
Reaction time mean0.00.00.1-0.1-0.3-0.1-0.20.20.00.1-0.1-0.0-0.10.10.1-0.10.00.3
Reaction time mean AUC0.00.00.1-0.0-0.20.0-0.20.20.1-0.00.00.20.00.10.20.00.10.4
Median of all reaction times0.00.00.2-0.1-0.1-0.1-0.30.30.10.0-0.00.1-0.00.10.0-0.00.10.4
Reaction time omissions0.40.64.20.30.20.5-0.70.70.7-0.50.50.40.50.60.60.80.72.0
Reaction time false alarm rate0.00.00.30.00.50.10.0-0.00.1-0.10.10.40.10.10.10.10.10.4
Reaction time premature initiation rate2.23.03.9-1.7-1.6-1.82.0-2.0-1.81.8-1.8-1.5-1.8-1.8-1.5-1.8-1.8-1.4
Reaction time premature initiations1.01.41.8-1.2-0.8-1.31.3-1.3-1.21.2-1.2-0.9-1.2-1.2-1.1-1.3-1.2-1.3
Std. dev. reaction times0.10.10.3-0.3-0.5-0.30.3-0.3-0.30.3-0.3-0.1-0.3-0.3-0.1-0.4-0.3-0.0
Reaction time trials completed0.50.71.10.71.10.7-1.11.10.9-0.80.80.90.80.90.50.80.90.5
Reaction time trials AUC0.60.91.40.81.10.8-1.21.21.0-0.90.91.00.91.00.60.91.00.5
Social response proportion0.50.50.8-0.9-0.4-0.80.7-0.7-0.70.8-0.8-0.3-0.8-0.7-0.8-0.7-0.8-0.6
Social responses0.40.50.8-0.7-0.4-0.70.9-0.9-0.70.7-0.7-0.3-0.7-0.7-0.7-0.7-0.8-0.9
Social time0.40.51.90.71.40.7-0.70.70.7-0.70.70.90.70.70.80.70.60.0
Conditioned locomotion3.03.64.11.81.91.8-1.91.91.9-1.91.92.01.91.91.91.91.91.9
Cocaine response after cond. corrected0.30.31.5-0.5-0.6-0.50.4-0.4-0.50.5-0.5-1.2-0.5-0.4-0.4-0.5-0.5-0.3
Cocaine response after cond. not corrected1.82.03.6-1.4-1.4-1.41.4-1.4-1.41.4-1.4-1.9-1.4-1.4-1.3-1.4-1.4-1.2
Cocaine response before conditioning1.21.52.4-1.0-0.9-1.11.4-1.4-1.31.2-1.2-0.6-1.2-1.4-1.1-1.2-1.3-1.6
Saline control response1.31.72.1-1.4-1.3-1.41.3-1.3-1.31.4-1.4-0.8-1.4-1.4-1.4-1.2-1.3-0.8
Condit. Reinf. active minus inactive responses2.12.72.9-1.5-1.7-1.61.7-1.7-1.71.6-1.6-1.7-1.6-1.6-1.7-1.7-1.6-1.5
Condit. Reinf. active-inactive response ratio1.81.92.5-1.2-1.4-1.31.4-1.4-1.41.3-1.3-1.6-1.3-1.4-1.3-1.5-1.4-1.4
Condit. Reinf. active responses1.82.52.9-1.5-1.6-1.61.7-1.7-1.61.6-1.6-1.7-1.6-1.6-1.6-1.6-1.6-1.1
Condit. Reinf. inactive responses0.00.10.50.10.20.1-0.00.00.1-0.10.10.20.10.10.10.30.20.7
Condit. Reinf. lever presses2.53.54.1-1.7-1.8-1.82.0-2.0-1.91.8-1.8-1.9-1.8-1.9-1.8-2.0-1.9-1.8
Condit. Reinf. lever reinforcers received2.02.83.2-1.6-1.6-1.61.8-1.8-1.71.7-1.7-1.7-1.7-1.7-1.7-1.7-1.7-1.1
Pavlov. Cond. lever latency0.40.61.10.60.70.6-0.80.80.8-0.70.70.70.70.70.80.80.81.0
Pavlov. Cond. magazine entry latency0.10.10.30.60.40.5-0.30.30.3-0.40.40.20.40.30.40.30.3-0.6
Pavlov. Cond. change in total contacts2.33.34.2-1.6-1.8-1.71.8-1.8-1.91.7-1.7-1.9-1.7-1.8-1.9-1.8-1.8-2.0
Pavlov. Cond. index score0.10.20.9-0.1-0.3-0.20.3-0.3-0.40.2-0.2-0.6-0.2-0.3-0.3-0.4-0.4-1.0
Pavlov. Cond. latency score0.10.10.90.0-0.2-0.10.3-0.3-0.30.1-0.1-0.4-0.1-0.3-0.2-0.3-0.3-1.0
Pavlov. Cond. lever contacts1.01.42.0-1.0-1.2-1.11.2-1.2-1.21.1-1.1-1.1-1.1-1.2-1.2-1.2-1.2-1.4
Pavlov. Cond. magazine entry number0.30.40.7-0.9-0.7-0.80.6-0.6-0.60.8-0.8-0.4-0.8-0.6-0.6-0.7-0.6-0.0
Pavlov. Cond. intertrial magazine entries0.50.72.30.50.80.6-0.80.80.8-0.70.70.90.70.90.50.90.81.5
Pavlov. Cond. lever-magazine prob. diff.0.10.11.0-0.0-0.2-0.10.3-0.3-0.30.2-0.2-0.5-0.2-0.3-0.2-0.3-0.3-1.0
Pavlov. Cond. response bias0.10.10.8-0.0-0.3-0.10.3-0.3-0.30.1-0.1-0.4-0.2-0.3-0.3-0.3-0.3-0.9
Conditioned reinforcement - actives0.40.41.30.70.20.7-0.50.50.7-0.70.70.40.70.60.70.70.71.2
Conditioned reinforcement - inactives0.91.01.41.01.21.0-1.11.11.1-1.01.00.51.11.11.01.11.00.6
Conditioned locomotion0.40.51.90.70.10.8-0.40.40.7-0.70.70.60.70.50.80.80.71.4
Intermittent access intake day 1-15 change0.70.72.10.81.40.8-0.90.90.8-0.80.80.40.80.80.80.70.80.3
Intermittent access intake escalation0.60.62.10.71.50.7-0.90.90.8-0.70.70.50.70.80.70.60.80.1
Intermittent access intake escalation 20.10.10.8-0.10.8-0.1-0.20.2-0.00.1-0.1-0.1-0.10.0-0.1-0.2-0.1-0.9
Intermitt. access day 1 inactive lever presses0.00.00.00.10.10.10.2-0.2-0.0-0.00.00.20.0-0.10.00.2-0.00.1
Intermitt. access day 15 inactive lever presses0.60.71.40.81.20.8-0.70.70.8-0.80.80.60.80.90.80.90.80.5
Intermitt. access escalation Index0.00.00.4-0.00.2-0.00.1-0.1-0.00.0-0.00.7-0.0-0.0-0.00.0-0.0-0.1
Intermittent access day 1 total infusions0.00.00.20.10.10.20.0-0.00.1-0.20.20.20.20.20.20.30.10.4
Intermittent access day 15 total infusions0.40.51.60.61.30.7-0.50.50.7-0.70.70.70.70.70.70.60.70.3
Intermittent access terminal intake (last 3 days)0.20.31.00.41.00.5-0.30.30.4-0.50.50.70.40.50.50.50.40.3
Intermittent access total infusions0.60.71.30.71.10.8-0.50.50.8-0.80.81.00.80.80.80.90.80.8
Intermittent access day 1 locomotion0.10.10.40.30.20.4-0.20.20.3-0.40.40.40.40.40.30.50.30.6
Intermittent access day 15 total locomotion0.80.81.90.81.00.8-1.01.00.9-0.80.81.40.91.00.80.80.80.4
Intermittent access total locomotion1.31.42.11.21.11.2-1.11.11.2-1.21.21.41.21.11.21.31.21.3
Intermittent access standard deviation0.20.20.5-0.40.2-0.40.3-0.3-0.40.4-0.4-0.7-0.4-0.3-0.4-0.4-0.4-0.7
Cocaine induced anxiety0.40.51.80.60.90.8-0.10.10.6-0.70.70.50.70.50.80.80.71.4
Post-drug Anxiety0.10.10.50.40.50.4-0.10.10.3-0.40.40.10.40.40.40.40.40.7
Baseline Anxiety0.30.30.90.50.50.4-1.01.00.6-0.40.40.70.50.70.30.30.5-0.5
Lifetime Intake0.40.50.70.70.80.7-0.60.60.7-0.70.70.90.70.70.70.80.70.6
Incentive Sensitization - Responses1.71.72.31.31.21.4-1.11.11.3-1.31.31.21.31.31.41.31.31.5
Incentive Sensitization - Breakpoint1.61.62.21.31.31.3-1.01.01.3-1.31.31.21.31.31.41.31.31.5
Progressive ratio test 1 active lever presses0.00.00.10.10.00.1-0.00.00.1-0.10.10.40.10.10.20.20.10.3
Progressive ratio test 1 breakpoint0.10.10.20.20.10.2-0.10.10.2-0.20.20.40.20.20.20.30.20.5
Progressive ratio test 1 inactive lever presses0.40.40.70.70.40.7-0.60.60.7-0.70.70.10.70.70.70.70.70.9
Progressive ratio test 2 active lever presses1.01.11.71.01.11.1-0.70.71.0-1.01.01.11.01.01.11.11.01.3
Progressive ratio test 2 breakpoint0.80.91.80.91.01.0-0.60.60.9-0.90.91.00.90.81.01.00.91.4
Progressive ratio test 2 inactive lever presses2.12.43.51.61.91.7-1.11.11.5-1.61.61.21.61.51.61.81.61.7
Total sessions with >9 infusions0.10.10.20.3-0.10.3-0.40.40.4-0.30.3-0.50.30.40.30.20.40.5
Short access day 1 total inactive lever presses4.14.66.82.21.72.1-2.62.62.3-2.22.21.52.22.42.02.12.21.3
Short access day 10 total inactive lever presses0.00.00.20.00.20.10.2-0.2-0.0-0.00.0-0.50.00.0-0.00.10.00.1
Short access day 1 total infusions0.91.01.21.00.41.0-1.11.11.1-1.01.00.41.01.11.01.01.01.0
Short access day 10 total infusions0.10.10.20.30.30.3-0.30.30.3-0.30.30.50.30.30.30.40.30.3
Short access total infusions0.60.70.90.80.60.8-1.01.00.9-0.80.80.90.80.90.80.80.80.6
Short access day 1 locomotion0.10.10.30.3-0.20.3-0.00.00.2-0.30.3-0.10.20.20.30.30.20.6
Short access day 10 total locomotion0.00.00.3-0.1-0.6-0.10.1-0.1-0.10.1-0.1-0.1-0.1-0.2-0.1-0.1-0.20.2
Short access total locomotion0.10.10.60.1-0.50.20.1-0.10.1-0.10.10.00.1-0.00.20.20.10.8
Compulsive drug intake0.10.10.50.10.00.0-0.50.50.2-0.10.10.70.10.3-0.0-0.00.1-0.6
One hour access (0.3 mA shock)0.30.31.20.50.80.5-0.50.50.5-0.50.51.10.50.60.50.40.50.1
One hour access (shock baseline)0.10.20.60.30.80.40.1-0.10.3-0.30.30.50.30.30.40.40.30.6
Number of responses in last shaping day0.80.81.50.91.20.9-0.70.70.9-0.90.90.70.90.90.90.90.90.8
Context. condit. distance diff. score0.00.00.0-0.00.2-0.00.1-0.1-0.00.0-0.0-0.0-0.00.0-0.0-0.1-0.0-0.2
Locomotion velocity, session 10.10.10.10.30.30.3-0.10.10.2-0.30.30.30.30.20.20.30.30.3
Locomotion distance, session 10.91.22.4-0.8-0.9-0.91.3-1.3-1.20.9-0.9-0.7-1.0-1.2-1.0-1.2-1.1-1.6
Locomotion velocity, session 20.20.30.50.70.70.6-0.40.40.5-0.60.60.40.60.50.60.50.50.0
Locomotion distance, session 20.10.10.30.40.40.2-0.00.00.0-0.20.20.50.20.00.10.00.0-0.6
Locomotion velocity, session 30.20.21.3-0.10.1-0.20.5-0.5-0.40.3-0.30.5-0.3-0.5-0.1-0.5-0.5-1.1
Locomotion distance, session 31.01.12.31.21.31.1-0.90.90.9-1.11.11.51.10.91.20.90.9-0.0
Stereotopy head waving bouts, day 30.10.10.8-0.2-0.2-0.20.1-0.1-0.10.2-0.2-0.9-0.2-0.1-0.2-0.1-0.10.0
Stereotopy head waving duration, day 30.20.30.6-0.6-0.5-0.60.3-0.3-0.40.5-0.5-0.8-0.5-0.4-0.7-0.4-0.4-0.1
Locomotion velocity, session 70.20.31.4-0.5-0.1-0.50.3-0.3-0.40.5-0.50.4-0.5-0.2-0.6-0.6-0.5-1.2
Locomotion distance, session 70.81.02.60.91.20.9-1.11.11.0-0.90.91.60.91.10.80.80.9-0.0
Stereotopy head waving bouts, day 70.00.00.10.20.20.2-0.20.20.2-0.20.20.20.20.10.30.20.20.1
Stereotopy head waving duration, day 70.30.30.4-0.5-0.6-0.60.6-0.6-0.60.6-0.6-0.5-0.6-0.7-0.4-0.6-0.6-0.6
Locomotion velocity, session 80.30.31.7-0.2-0.3-0.40.7-0.7-0.60.4-0.4-0.1-0.4-0.6-0.4-0.7-0.6-1.3
Locomotion distance, session 80.30.52.8-0.2-0.0-0.40.7-0.7-0.70.4-0.40.3-0.4-0.6-0.4-0.7-0.7-1.7
Degree of sensitization distance1.11.11.7-1.3-1.2-1.20.9-0.9-1.01.2-1.2-1.1-1.1-0.9-1.3-1.0-1.0-0.7
Degree of sensitization stereotypy0.00.00.1-0.2-0.2-0.20.2-0.2-0.20.2-0.20.1-0.2-0.30.1-0.2-0.2-0.0
Condit. Reinf. active minus inactive responses0.10.10.2-0.4-0.2-0.40.2-0.2-0.20.3-0.3-0.4-0.3-0.2-0.4-0.2-0.20.1
Condit. Reinf. active-inactive response ratio0.20.30.6-0.6-0.5-0.50.4-0.4-0.40.5-0.5-0.8-0.5-0.4-0.6-0.4-0.40.2
Condit. Reinf. active responses0.00.00.10.00.30.1-0.20.20.2-0.10.1-0.00.10.20.20.10.10.1
Condit. Reinf. inactive responses0.60.71.30.91.00.8-0.80.80.8-0.80.80.80.80.81.10.70.80.1
Incentive salience index mean0.10.10.10.20.40.3-0.20.20.3-0.30.30.20.20.30.20.30.20.3
Condit. Reinf. lever presses1.52.02.31.51.51.5-1.31.31.4-1.51.51.31.51.31.41.41.41.1
Time in familiar zone, hab. session 11.71.62.61.01.21.1-1.51.51.3-1.21.20.81.21.40.91.31.31.6
Time in novel zone, hab. session 10.80.81.2-0.8-0.6-0.81.1-1.1-0.90.8-0.8-0.6-0.8-1.0-0.6-0.9-0.9-0.9
Total zone transitions, hab. session 10.60.93.1-0.7-0.5-0.81.0-1.0-1.00.8-0.8-0.2-0.8-1.0-0.8-1.1-1.0-1.8
Total locomotion distance, hab. session 10.30.40.8-0.4-0.6-0.50.7-0.7-0.70.6-0.6-0.4-0.6-0.7-0.4-0.7-0.7-0.9
Locomotion velocity, hab. session 10.30.40.8-0.5-0.6-0.60.8-0.8-0.70.6-0.6-0.3-0.6-0.8-0.4-0.7-0.7-0.9
Time in familiar zone, hab. session 20.60.61.00.80.70.8-1.01.00.9-0.80.80.30.80.90.60.80.90.6
Time in novel zone, hab. session 20.00.00.1-0.2-0.1-0.20.3-0.3-0.20.2-0.20.2-0.2-0.2-0.2-0.1-0.20.1
Total zone transitions, hab. session 20.20.21.90.00.1-0.10.4-0.4-0.40.2-0.20.0-0.2-0.4-0.2-0.4-0.4-1.4
Total locomotion distance, hab. session 20.30.40.9-0.4-0.7-0.50.8-0.8-0.70.5-0.5-0.5-0.5-0.8-0.4-0.7-0.7-1.0
Locomotion velocity, hab. session 20.20.30.6-0.3-0.6-0.40.7-0.7-0.60.4-0.4-0.4-0.5-0.7-0.3-0.6-0.6-0.8
Novel to familiar place preference ratio0.70.81.7-0.8-1.0-0.90.7-0.7-0.90.9-0.90.1-0.9-0.9-1.0-0.9-0.9-1.3
Novelty place preference0.70.81.4-0.9-1.0-0.90.7-0.7-0.90.9-0.90.1-0.9-0.9-1.0-0.9-0.9-1.2
Time in novel zone, NPP test0.91.01.4-1.0-1.1-1.10.8-0.8-1.01.0-1.0-0.1-1.0-1.0-1.2-1.0-1.0-1.2
Total zone transitions, NPP test2.43.58.7-1.4-1.4-1.62.1-2.1-2.01.7-1.7-1.0-1.7-2.1-1.5-2.1-2.0-2.9
Total locomotion distance, NPP test1.11.52.6-0.9-1.2-1.11.4-1.4-1.31.1-1.1-1.1-1.1-1.4-0.9-1.3-1.3-1.6
Locomotion velocity, NPP test1.21.73.3-1.0-1.2-1.11.5-1.5-1.41.2-1.2-1.0-1.2-1.5-1.0-1.4-1.4-1.8
Pavlov. Cond. lever latency5.06.37.8-2.8-2.4-2.72.4-2.4-2.52.7-2.7-2.0-2.7-2.4-2.7-2.6-2.5-2.0
Pavlov. Cond. magazine entry latency6.58.49.23.03.03.0-2.92.92.9-3.03.02.33.02.92.93.03.02.6
Pavlov. Cond. change in total contacts1.81.92.91.41.11.4-1.41.41.5-1.41.40.81.41.41.31.51.51.7
Pavlov. Cond. index score6.48.29.13.02.73.0-2.82.82.9-3.03.02.23.02.82.93.02.92.7
Pavlov. Cond. latency score6.28.09.03.02.73.0-2.82.82.9-3.03.02.23.02.82.92.92.92.6
Pavlov. Cond. lever contacts2.93.44.32.11.72.0-1.71.71.8-2.02.01.42.01.72.01.91.81.6
Pavlov. Cond. magazine entry number7.69.510.4-3.2-3.0-3.23.1-3.1-3.13.2-3.2-2.4-3.2-3.1-3.0-3.2-3.2-2.8
Pavlov. Cond. intertrial magazine entries0.40.41.1-0.7-0.5-0.70.5-0.5-0.60.7-0.7-0.3-0.7-0.5-0.7-0.7-0.7-1.0
Pavlov. Cond. lever-magazine prob. diff.5.77.18.02.82.52.8-2.62.62.7-2.82.81.82.82.72.72.82.82.5
Pavlov. Cond. response bias6.98.59.53.12.83.1-2.92.93.0-3.13.12.23.12.93.03.03.02.6
Bone: apparent density0.10.11.0-0.1-0.1-0.20.1-0.1-0.20.2-0.20.4-0.2-0.2-0.2-0.2-0.2-1.0
Bone surface0.10.20.90.40.60.3-0.30.30.2-0.30.30.60.30.20.30.10.2-0.9
Bone volume0.10.11.40.20.40.1-0.10.10.1-0.10.10.50.10.00.2-0.00.0-1.2
Bone: connectivity density0.20.31.40.50.50.5-0.60.60.6-0.50.51.20.50.50.60.60.50.4
Bone: cortical apparent density0.30.30.60.50.60.5-0.60.60.6-0.50.50.70.50.50.60.60.50.7
Bone: cortical area0.10.20.70.50.90.5-0.50.50.5-0.50.5-0.00.50.50.30.40.5-0.0
Bone: cortical porosity0.10.10.8-0.0-0.10.1-0.30.30.3-0.10.10.70.10.30.10.20.30.9
Bone: cortical porosity0.30.31.40.20.20.4-0.50.50.5-0.40.41.00.40.60.30.50.51.2
Bone: cortical thickness0.10.20.9-0.30.0-0.40.3-0.3-0.30.3-0.3-1.0-0.3-0.3-0.4-0.4-0.3-0.9
Bone: cortical thickness0.00.00.2-0.0-0.0-0.1-0.10.1-0.00.0-0.0-0.1-0.00.0-0.1-0.1-0.0-0.4
Bone: cortical tissue density0.30.30.60.50.60.5-0.60.60.6-0.50.50.80.50.50.70.60.60.8
Bone: elastic displacement0.10.10.4-0.2-0.3-0.20.2-0.2-0.20.2-0.2-0.6-0.2-0.2-0.3-0.2-0.1-0.2
Bone: elastic work0.60.72.9-0.6-0.5-0.70.8-0.8-0.80.7-0.7-1.0-0.7-0.8-0.8-0.9-0.8-1.7
Bone: endosteal estimation0.10.10.3-0.4-0.3-0.40.2-0.2-0.30.4-0.40.1-0.4-0.1-0.6-0.3-0.3-0.4
Bone: endosteal perimeter1.22.43.51.61.91.6-1.51.51.5-1.61.61.71.61.51.41.61.61.2
Bone: final force0.91.42.1-1.1-0.8-1.11.2-1.2-1.21.2-1.2-1.4-1.2-1.1-1.2-1.2-1.2-1.4
Bone: final moment1.11.82.8-1.3-0.9-1.31.4-1.4-1.41.3-1.3-1.7-1.3-1.3-1.4-1.4-1.3-1.6
Bone: marrow area0.10.10.4-0.5-0.3-0.40.2-0.2-0.30.4-0.40.1-0.4-0.2-0.6-0.4-0.3-0.5
Bone: maximum diameter0.40.71.30.91.10.9-0.80.80.9-0.90.90.40.90.80.81.00.90.7
Bone: maximum force0.71.21.9-1.1-0.7-1.11.0-1.0-1.11.1-1.1-1.0-1.1-1.0-1.2-1.1-1.0-1.4
Bone: maximum moment0.81.42.2-1.2-0.7-1.21.1-1.1-1.21.2-1.2-1.2-1.2-1.1-1.3-1.2-1.1-1.5
Bone: minimum diameter0.40.71.50.91.20.8-0.90.90.8-0.90.90.90.90.90.70.80.90.0
Bone: periosteal estimation0.00.00.3-0.10.3-0.10.0-0.0-0.10.1-0.10.0-0.10.1-0.3-0.1-0.0-0.6
Bone: periosteal perimeter1.22.03.21.41.81.5-1.41.41.4-1.41.41.41.41.51.31.51.51.0
Bone: post-yield work0.00.10.5-0.10.0-0.20.2-0.2-0.20.2-0.20.0-0.2-0.1-0.3-0.2-0.2-0.7
Bone: stiffness0.10.20.3-0.5-0.2-0.50.4-0.4-0.40.5-0.5-0.3-0.5-0.3-0.5-0.5-0.4-0.4
Bone: tissue strength2.92.83.5-1.7-1.4-1.71.6-1.6-1.71.7-1.7-1.9-1.7-1.6-1.8-1.7-1.7-1.7
Bone: trabecular number0.61.02.91.01.11.0-1.01.00.9-1.01.01.71.00.91.00.90.9-0.1
Bone: trabecular spacing1.41.93.6-1.4-1.3-1.41.3-1.3-1.31.4-1.4-1.9-1.4-1.2-1.3-1.4-1.3-0.9
Bone: trabecular thickness0.10.11.1-0.0-0.2-0.10.2-0.2-0.20.1-0.10.3-0.1-0.3-0.0-0.3-0.2-1.0
Bone: trabecular tissue density0.20.30.4-0.6-0.4-0.60.7-0.7-0.60.6-0.6-0.3-0.6-0.6-0.5-0.6-0.6-0.6
Breakpoint value in progressive ratio session0.10.10.5-0.3-0.7-0.30.4-0.4-0.30.3-0.3-0.6-0.3-0.2-0.1-0.3-0.30.5
Distance traveled before self-admin0.00.10.5-0.00.2-0.1-0.30.30.00.0-0.00.10.00.2-0.3-0.10.0-0.7
Distance traveled after self-admin0.20.30.80.50.90.4-0.50.50.5-0.50.50.60.50.60.10.40.5-0.4
Delta time in closed arm before/after self-admin0.20.20.60.40.10.4-0.70.70.5-0.40.40.10.40.50.40.40.40.0
Delta time in open arm before/after self-admin0.40.41.7-0.50.4-0.50.5-0.5-0.50.5-0.50.4-0.5-0.5-0.6-0.6-0.5-1.3
Diff in mean of infusions in LGA sessions0.10.10.50.0-0.20.10.1-0.10.0-0.10.1-0.70.00.00.30.10.10.6
Extinction: sum of active levers before priming0.00.00.3-0.1-0.3-0.10.1-0.1-0.10.1-0.1-0.0-0.10.0-0.0-0.2-0.00.5
Active lever presses in extinction session 60.30.30.4-0.6-0.1-0.60.7-0.7-0.50.5-0.50.6-0.5-0.5-0.4-0.6-0.5-0.2
Delta distance traveled before/after self-admin0.10.20.60.40.80.40.1-0.10.3-0.40.40.60.40.20.20.40.30.3
Delta ambulatory time before/after self-admin0.30.40.8-0.5-0.0-0.50.9-0.9-0.60.5-0.5-0.2-0.5-0.6-0.7-0.5-0.6-0.8
Time in closed arm before self-admin1.41.71.9-1.3-1.0-1.41.2-1.2-1.31.3-1.3-1.2-1.3-1.3-1.3-1.4-1.3-1.3
Time in closed arm after self-admin0.10.10.4-0.0-0.2-0.1-0.30.3-0.00.1-0.1-0.7-0.1-0.0-0.1-0.1-0.1-0.3
Time in open arm before self-admin1.11.21.81.10.81.1-0.90.91.1-1.11.10.91.11.11.31.21.11.3
Time in open arm after self-admin0.40.42.50.41.20.4-0.30.30.4-0.40.41.60.40.40.40.40.4-0.2
Sum of active levers in priming session hrs 5-60.50.50.8-0.8-0.7-0.70.9-0.9-0.80.8-0.8-0.3-0.8-0.9-0.5-0.7-0.7-0.0
Time to tail flick, vehicle, before self-admin2.12.14.2-1.5-1.9-1.41.2-1.2-1.41.4-1.4-2.0-1.4-1.4-1.3-1.4-1.4-0.8
Time to tail flick, vehicle, after self-admin0.60.71.0-0.8-0.8-0.81.0-1.0-0.90.8-0.8-0.6-0.8-1.0-0.8-0.7-0.9-0.3
Time to tail flick, test, before self-admin0.10.10.2-0.3-0.2-0.30.4-0.4-0.40.3-0.30.3-0.3-0.5-0.1-0.2-0.3-0.2
Time to tail flick, test, after self-admin0.20.21.10.30.10.4-0.00.00.3-0.30.3-0.00.30.20.50.50.31.1
Delta time to tail flick, vehicle, before/after SA0.40.40.70.70.80.7-0.50.50.6-0.70.70.90.70.60.50.70.60.7
Delta time to tail flick, test, before/after SA0.40.30.90.50.30.6-0.50.50.6-0.60.60.10.60.60.60.60.60.9
Ambulatory time before self-admin0.10.10.40.30.50.2-0.60.60.4-0.30.30.20.30.50.10.20.3-0.4
Ambulatory time after self-admin0.10.10.50.20.70.1-0.10.10.1-0.10.10.50.10.2-0.20.00.1-0.7
Total heroin consumption1.21.41.9-1.2-0.8-1.21.4-1.4-1.21.2-1.2-1.2-1.2-1.1-1.2-1.2-1.2-1.3
Area under the delay curve2.02.23.01.51.31.5-1.21.21.5-1.51.51.71.51.51.51.51.51.7
Delay disc. indifference point, 0s delay0.00.00.10.2-0.30.2-0.20.20.2-0.20.20.10.20.20.20.20.20.4
Delay disc. indifference point, 16s delay1.11.12.21.01.31.1-0.90.91.0-1.01.01.51.00.91.01.21.00.8
Delay disc. indifference point, 2s delay0.30.30.70.50.60.6-0.30.30.5-0.50.50.80.50.50.70.40.50.7
Delay disc. indifference point, 24s delay0.90.92.00.91.20.9-0.80.80.9-0.90.91.40.90.90.90.90.90.7
Delay disc. indifference point, 4s delay2.02.13.31.41.31.5-1.21.21.4-1.51.51.51.51.51.61.51.51.8
Delay disc. indifference point, 8s delay2.02.12.81.41.31.5-1.31.31.4-1.51.51.71.41.51.51.51.51.6
Delay discount exponential model param2.42.53.3-1.6-1.4-1.61.4-1.4-1.61.6-1.6-1.7-1.6-1.6-1.7-1.7-1.6-1.8
Delay discount hyperbolic model param2.32.53.4-1.6-1.4-1.61.3-1.3-1.61.6-1.6-1.7-1.6-1.6-1.7-1.6-1.6-1.9
Fecal boli incidents, locomotor time 10.40.51.4-0.7-0.9-0.60.6-0.6-0.60.6-0.6-1.2-0.6-0.6-0.7-0.6-0.6-0.2
Change in fecal boli incidents, locomotor task0.10.10.6-0.1-0.8-0.20.2-0.2-0.10.1-0.1-0.5-0.1-0.1-0.1-0.2-0.10.1
Time >=10cm from walls, locomotor time 10.20.20.30.40.30.3-0.60.60.4-0.30.30.60.30.40.30.30.4-0.1
Bouts of movement, locomotor time 10.00.00.2-0.1-0.5-0.10.3-0.3-0.10.1-0.1-0.3-0.1-0.2-0.1-0.1-0.10.1
Total resting periods, locomotor time 10.00.10.4-0.1-0.6-0.10.2-0.2-0.10.1-0.1-0.4-0.1-0.1-0.1-0.1-0.10.2
Rest time, locomotor task time 10.60.71.40.8-0.30.8-0.90.90.9-0.80.80.20.80.90.80.90.91.2
Distance moved, locomotor task time 11.61.82.3-1.3-0.9-1.41.3-1.3-1.41.4-1.4-1.2-1.4-1.4-1.4-1.4-1.4-1.5
Vertical activity count, locomotor time 10.90.91.1-0.9-0.8-0.91.0-1.0-1.01.0-1.0-1.0-1.0-1.1-0.9-1.0-1.0-0.8
Time >=10cm from walls, locomotor time 21.41.51.7-1.2-1.3-1.31.0-1.0-1.21.3-1.3-1.1-1.3-1.2-1.3-1.3-1.3-1.3
Bouts of movement, locomotor time 20.00.00.1-0.00.2-0.0-0.10.10.00.0-0.0-0.10.00.1-0.1-0.0-0.0-0.2
Total resting periods, locomotor time 20.10.10.20.20.40.3-0.40.40.3-0.30.30.20.30.40.20.20.3-0.0
Rest time, locomotor task time 20.10.10.20.2-0.40.2-0.20.20.3-0.20.2-0.20.20.30.10.20.30.5
Distance moved, locomotor task time 21.01.11.8-1.1-0.4-1.11.0-1.0-1.11.1-1.1-0.6-1.1-1.2-1.1-1.1-1.1-1.4
Vertical activity count, locomotor time 20.10.10.3-0.20.1-0.30.2-0.2-0.30.3-0.30.1-0.3-0.4-0.2-0.3-0.3-0.5
Weight adjusted by age0.30.30.9-0.50.1-0.50.9-0.9-0.60.5-0.5-0.1-0.5-0.6-0.5-0.5-0.6-0.5
Seeking ratio, delayed vs. immediate footshock2.42.74.51.70.71.8-1.51.51.8-1.81.80.91.81.91.71.41.92.1
Locomotion in novel chamber0.20.20.70.5-0.30.5-0.30.30.4-0.50.5-0.50.50.30.50.60.40.8
Locomotion in novel chamber post-restriction0.80.92.0-0.9-1.4-1.00.8-0.8-0.90.9-0.9-1.3-0.9-1.0-0.9-0.9-0.9-0.9
Progressive ratio3.54.15.3-1.9-2.3-2.02.1-2.1-2.02.0-2.0-2.1-2.0-2.0-2.1-1.9-2.0-1.7
Food seeking constrained by brief footshock0.81.01.91.11.41.0-1.11.11.0-1.01.01.31.00.80.91.00.90.2
Seeking ratio, punishment vs. effort5.56.89.12.63.02.6-2.72.72.6-2.62.62.62.62.52.72.62.61.9
Run reversals in cocaine runway, females1.91.92.91.41.61.3-1.71.71.4-1.31.31.41.31.31.51.31.30.2
Run reversals in cocaine runway, males0.80.71.2-0.8-0.6-0.81.1-1.1-0.90.8-0.8-1.1-0.8-0.8-0.9-0.8-0.8-0.5
Latency to leave start box in cocaine runway0.50.51.5-0.6-1.1-0.60.8-0.8-0.70.6-0.6-1.2-0.6-0.8-0.7-0.5-0.7-0.1
Latency to leave start box in cocaine runway, F1.41.52.7-1.2-1.0-1.21.2-1.2-1.31.2-1.2-1.6-1.2-1.3-1.4-1.1-1.2-1.1
Latency to leave start box in cocaine runway, M0.40.42.30.5-0.40.6-0.20.20.5-0.50.50.10.50.30.80.60.51.5
Cd content in liver2.22.43.7-1.8-1.8-1.61.4-1.4-1.51.6-1.6-1.9-1.6-1.4-1.8-1.4-1.40.3
Co content in liver0.10.10.6-0.10.8-0.0-0.10.10.00.0-0.00.4-0.00.2-0.30.10.0-0.5
Cu content in liver3.94.77.1-2.2-2.7-2.22.2-2.2-2.22.2-2.2-2.3-2.2-2.1-2.3-2.1-2.1-1.4
Fe content in liver1.62.03.7-1.7-1.9-1.51.1-1.1-1.21.5-1.5-1.9-1.5-1.2-1.6-1.0-1.20.7
K content in liver0.90.91.9-0.7-1.1-0.81.0-1.0-1.00.8-0.8-1.0-0.9-1.1-0.7-0.9-1.0-1.4
Mg content in liver0.10.11.30.2-0.00.10.2-0.2-0.2-0.00.00.00.0-0.20.1-0.1-0.2-1.2
Mn content in liver0.70.83.4-0.6-0.4-0.81.0-1.0-1.00.8-0.80.0-0.8-1.0-0.8-0.9-1.0-1.8
Na content in liver0.30.30.6-0.8-0.7-0.70.5-0.5-0.50.7-0.7-0.4-0.7-0.5-0.6-0.4-0.50.3
Rb content in liver0.91.12.5-1.5-1.2-1.20.6-0.6-0.81.2-1.2-1.3-1.2-0.6-1.6-0.6-0.80.5
Se content in liver0.10.10.2-0.1-0.4-0.20.1-0.1-0.30.2-0.2-0.5-0.2-0.40.2-0.3-0.3-0.5
Sr content in liver0.20.22.10.20.10.00.3-0.3-0.2-0.00.00.1-0.0-0.30.1-0.3-0.2-1.5
Zn content in liver4.44.96.7-2.1-2.6-2.12.2-2.2-2.32.2-2.2-2.3-2.2-2.3-2.3-2.1-2.2-1.7