Dhcr7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000020776 0.14 0.06 2.8e-16 0.13 0.13 0.13 0.13 3.1e-14 1.7e-14 2.2e-14 2.3e-14
2 Adipose isoform ratio ENSRNOT00000028195 0.07 0.04 5.1e-07 0.05 0.05 0.06 0.06 3.8e-06 1.7e-06 5.6e-07 7.7e-07
3 Adipose isoform ratio ENSRNOT00000078979 0.08 0.04 2.9e-07 0.04 0.05 0.06 0.06 3.9e-05 1.2e-06 3.6e-07 4.8e-07
4 BLA gene expression ENSRNOG00000020776 0.08 0.05 5.3e-04 0.03 0.03 0.02 0.03 1.2e-02 6.6e-03 4.4e-02 1.2e-02
5 BLA isoform ratio ENSRNOT00000028195 0.11 0.05 1.5e-05 0.08 0.06 0.07 0.08 4.0e-05 4.9e-04 1.6e-04 7.2e-05
6 BLA isoform ratio ENSRNOT00000078979 0.1 0.05 2.4e-05 0.08 0.06 0.07 0.07 4.8e-05 6.6e-04 1.5e-04 8.0e-05
7 BLA intron excision ratio chr1:199015270:199020916 0.19 0.07 5.5e-09 0.16 0.15 0.14 0.16 9.2e-09 2.6e-08 5.1e-08 4.2e-09
8 BLA intron excision ratio chr1:199015270:199021037 0.2 0.07 9.4e-10 0.17 0.16 0.15 0.15 1.1e-09 1.2e-08 2.3e-08 2.1e-08
9 Brain isoform ratio ENSRNOT00000028195 0.19 0.09 5.6e-17 0.2 0.19 0.18 0.2 1.2e-18 4.3e-17 7.3e-17 5.8e-18
10 Brain isoform ratio ENSRNOT00000078979 0.19 0.09 5.6e-17 0.2 0.19 0.19 0.2 1.0e-18 3.4e-17 4.8e-17 4.1e-18
11 Brain intron excision ratio chr1:199015270:199020916 0.07 0.04 3.1e-06 0.02 0.06 0.04 0.06 2.8e-03 2.9e-06 1.5e-04 4.7e-06
12 Brain intron excision ratio chr1:199015270:199021037 0.12 0.06 1.3e-10 0.06 0.12 0.12 0.13 1.2e-06 2.3e-11 2.4e-11 6.7e-12
13 IL gene expression ENSRNOG00000020776 0.15 0.09 5.4e-03 0.03 0.03 0.01 0.01 5.3e-02 6.7e-02 1.9e-01 2.1e-01
14 Liver gene expression ENSRNOG00000020776 0.25 0.12 7.6e-04 0.01 0.03 0.04 0 1.9e-02 3.5e-04 8.9e-05 1.1e-01
15 Liver isoform ratio ENSRNOT00000028195 0.32 0.1 0.0e+00 0.22 0.26 0.29 0.25 6.5e-24 2.5e-29 9.0e-33 1.0e-27
16 Liver isoform ratio ENSRNOT00000078979 0.37 0.11 0.0e+00 0.24 0.29 0.32 0.26 6.0e-26 6.7e-32 6.3e-36 1.3e-28
17 Liver intron excision ratio chr1:199015270:199020916 0.2 0.07 0.0e+00 0.23 0.22 0.2 0.23 7.2e-25 9.7e-24 8.6e-22 1.4e-25
18 Liver intron excision ratio chr1:199015270:199021037 0.18 0.07 0.0e+00 0.25 0.22 0.22 0.25 2.6e-27 2.3e-24 1.7e-24 2.2e-27
19 Liver intron excision ratio chr1:199018307:199020916 0.06 0.06 1.4e-03 0.02 0.02 0.02 0.01 4.7e-03 5.9e-03 6.5e-03 8.3e-03
20 NAcc isoform ratio ENSRNOT00000078979 0.05 0.03 9.6e-03 0.02 0.01 0.02 0.01 2.3e-02 2.4e-02 2.2e-02 4.5e-02
21 NAcc intron excision ratio chr1:199015270:199021037 0.05 0.03 1.7e-03 0.01 0.03 0.03 0.02 1.1e-01 1.5e-03 5.6e-03 1.9e-02
22 PL isoform ratio ENSRNOT00000028195 0.07 0.04 8.1e-05 0.05 0.03 0.03 0.03 8.5e-05 3.1e-03 2.5e-03 4.1e-03
23 PL isoform ratio ENSRNOT00000078979 0.07 0.04 9.6e-05 0.04 0.03 0.03 0.03 2.8e-04 3.9e-03 3.5e-03 5.2e-03
24 PL intron excision ratio chr1:199015270:199020916 0.1 0.05 1.1e-06 0.06 0.08 0.09 0.09 1.6e-05 9.5e-07 1.6e-07 1.3e-07
25 PL intron excision ratio chr1:199015270:199021037 0.09 0.04 1.0e-06 0.04 0.07 0.06 0.08 2.5e-04 6.3e-06 1.5e-05 2.0e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
BMI with tail0.41.43.21.10.7-0.7-1.11.6-1.50.5-0.41.8-1.81.1-1.3-1.3-0.41.4-1.30.3-0.3-1.5-1.0-1.21.6-1.60.6-1.0
BMI without tail1.02.04.31.81.4-1.4-0.91.7-1.21.3-1.11.9-1.91.8-1.6-0.9-1.11.4-1.11.0-1.0-0.9-0.7-2.11.4-1.41.3-1.8
Body weight0.10.30.90.60.4-0.40.10.6-0.60.2-0.20.9-0.90.3-0.70.0-0.90.5-0.40.1-0.2-0.8-0.7-0.40.6-0.60.3-0.3
Epididymis fat weight0.61.36.1-0.90.6-0.6-1.71.4-1.40.4-0.31.7-1.70.5-1.0-2.51.81.1-1.00.2-0.4-1.0-0.4-0.41.3-1.30.5-0.8
Glucose1.01.53.1-1.2-1.11.1-1.81.0-1.6-1.21.31.2-1.2-0.50.2-1.61.21.3-1.3-1.31.4-1.5-0.40.51.7-1.7-1.10.6
Heart weight0.71.12.5-1.1-0.50.5-1.00.9-1.5-0.70.71.0-1.0-0.5-0.3-1.31.51.2-1.4-0.90.9-1.2-0.70.61.6-1.6-0.70.7
Left kidney weight1.23.48.01.72.3-2.3-0.22.0-1.02.0-2.11.8-1.82.3-2.8-1.41.01.3-1.32.1-2.1-1.3-2.8-2.00.8-0.82.1-1.9
Right kidney weight1.43.98.31.82.5-2.5-0.22.1-1.52.1-2.12.3-2.32.2-2.9-0.90.21.5-1.52.1-2.1-1.1-2.8-2.21.4-1.42.3-2.1
Tail length0.51.43.51.31.0-1.01.6-0.91.51.1-1.2-0.80.80.6-0.31.8-1.9-1.11.21.2-1.21.1-0.0-0.7-1.61.61.1-0.8
Length with tail0.31.04.1-0.0-0.30.31.9-1.31.3-0.30.1-1.31.3-0.90.72.0-0.5-1.21.0-0.0-0.00.90.00.9-1.51.5-0.31.0
Length without tail0.40.92.4-1.0-0.90.91.1-1.00.7-1.00.8-1.11.1-1.30.90.90.7-0.90.7-0.70.70.20.11.5-0.80.8-0.91.5
Liver weight, left0.71.13.5-0.3-0.30.3-0.91.3-1.7-0.50.51.6-1.60.1-0.8-0.80.51.3-1.1-0.60.6-1.9-1.5-0.11.8-1.8-0.40.1
Liver weight, right0.81.34.9-0.60.0-0.0-1.11.7-1.7-0.20.31.7-1.70.1-1.1-0.8-0.41.5-1.7-0.30.3-2.2-1.3-0.21.7-1.7-0.1-0.4
Parametrial fat weight1.32.67.31.11.2-1.2-1.11.8-1.71.0-0.92.3-2.31.6-1.7-1.62.71.8-1.90.9-0.9-1.0-2.0-1.42.0-2.00.8-1.0
Retroperitoneal fat weight1.24.09.50.01.5-1.5-2.02.5-2.21.2-1.12.8-2.81.7-2.4-3.12.82.1-2.11.1-1.2-1.7-2.0-1.52.3-2.31.4-1.7
Intraocular pressure0.50.82.5-0.60.0-0.01.0-1.11.20.2-0.2-0.90.9-0.70.71.2-1.6-1.21.20.0-0.01.21.00.6-1.21.20.00.1
Extensor digitorum longus weight0.51.85.11.70.5-0.51.8-1.61.90.8-0.9-1.61.60.40.12.3-1.7-1.71.70.9-1.01.20.7-0.5-1.91.90.8-0.4
Soleus weight0.61.83.01.41.7-1.7-0.41.2-0.71.6-1.51.5-1.51.7-1.7-0.81.01.0-1.01.4-1.5-0.2-1.5-1.60.9-0.91.6-1.6
Tibialis anterior weight1.55.115.52.62.2-2.22.3-1.62.42.6-2.6-1.51.51.5-1.12.6-3.9-2.12.52.3-2.41.80.3-1.7-2.62.62.6-2.2
Tibia length0.00.10.3-0.10.4-0.40.5-0.20.40.4-0.5-0.20.20.0-0.20.20.1-0.50.30.5-0.40.5-0.40.1-0.40.40.3-0.0
Number of licking bursts0.10.10.30.50.1-0.1-0.40.1-0.10.2-0.10.1-0.10.5-0.3-0.40.20.2-0.20.1-0.1-0.3-0.3-0.50.2-0.20.2-0.4
Food consumed during 24 hour testing period0.40.51.3-0.4-0.40.4-1.00.7-0.9-0.50.51.0-1.00.1-0.2-0.91.20.9-1.0-0.60.6-1.0-0.7-0.11.0-1.0-0.40.1
Times rat made contact with spout0.30.34.60.3-0.30.30.2-0.70.6-0.30.2-0.40.4-0.00.4-0.42.2-0.40.2-0.20.20.6-0.80.3-0.20.2-0.40.7
Mean time between licks in bursts1.21.74.3-0.3-0.70.71.2-2.01.6-0.60.4-2.12.1-1.01.51.0-0.0-1.71.7-0.40.41.51.21.2-1.71.7-0.71.2
Mean num. licks in bursts0.20.31.3-0.5-0.60.60.2-0.30.2-0.60.6-0.20.2-0.60.7-0.11.1-0.20.0-0.60.60.4-0.10.7-0.00.0-0.70.9
Std. dev. time between licks in bursts1.41.65.20.80.7-0.72.1-1.51.80.7-1.0-1.61.6-0.10.61.70.2-1.71.61.0-1.02.30.10.4-1.81.80.50.5
Water consumed over 24 hours0.70.91.9-0.9-1.31.3-0.6-0.2-0.3-1.41.30.1-0.1-0.90.9-0.61.20.4-0.5-1.41.4-0.3-0.50.90.6-0.6-1.41.3
Indifference point 0 sec0.20.30.7-0.3-0.80.8-0.2-0.1-0.3-0.80.8-0.20.2-0.30.3-0.1-0.10.3-0.4-0.70.7-0.8-0.40.30.2-0.2-0.90.6
Indifference point AUC0.10.11.70.1-0.30.30.2-0.20.1-0.30.2-0.10.1-0.40.20.7-1.30.0-0.3-0.10.0-0.0-0.50.10.4-0.4-0.20.3
Indifference point function ln k0.20.35.9-0.10.4-0.40.2-0.10.30.4-0.5-0.10.10.3-0.0-0.32.4-0.20.20.4-0.40.7-0.10.1-0.30.30.30.1
Indifference point function log k0.20.35.9-0.10.4-0.40.2-0.10.30.4-0.5-0.10.10.3-0.0-0.32.4-0.20.20.4-0.40.7-0.10.1-0.30.30.30.1
Delay discounting total patch changes 0 sec0.20.30.6-0.1-0.70.70.5-0.70.3-0.70.6-0.70.7-0.50.60.6-0.4-0.30.2-0.50.6-0.1-0.30.5-0.40.4-0.80.8
Delay discounting total patch changes 12 sec0.30.41.41.00.3-0.30.8-0.80.70.4-0.4-0.60.60.4-0.41.0-1.2-0.50.50.6-0.5-0.1-0.6-0.5-0.50.50.4-0.3
Delay discounting total patch changes 18 sec0.40.51.80.6-0.00.0-0.40.8-0.7-0.10.20.7-0.70.5-0.6-0.4-0.91.1-1.30.10.0-1.2-1.3-0.71.0-1.0-0.1-0.2
Delay discounting total patch changes 24 sec0.20.31.00.3-0.30.30.6-0.81.0-0.20.2-0.90.9-0.20.60.7-0.2-0.60.50.0-0.00.70.30.2-0.60.6-0.30.4
Delay discounting total patch changes 6 sec0.91.34.5-1.1-1.51.5-0.80.2-1.2-1.61.60.2-0.2-1.10.6-0.1-2.10.8-1.0-1.51.4-1.7-0.30.81.0-1.0-1.51.0
Delay discounting time to switch 0 sec1.52.24.71.61.1-1.1-1.22.2-1.71.0-0.81.7-1.71.9-1.9-1.1-1.71.7-1.40.9-0.8-2.1-0.7-2.11.1-1.11.2-1.9
Delay discounting water rate 0 sec0.81.34.6-0.9-0.40.41.1-1.71.4-0.30.1-1.21.2-1.11.21.02.2-1.41.2-0.30.32.00.21.4-1.11.1-0.51.2
Delay discounting water rate 12 sec0.40.65.8-0.80.1-0.1-0.1-0.91.00.2-0.2-0.60.6-0.20.5-0.32.4-0.91.00.1-0.21.40.70.5-0.60.60.10.1
Delay discounting water rate 18 sec0.40.54.70.50.8-0.80.3-0.40.70.8-0.9-0.10.10.5-0.20.22.2-0.40.40.7-0.71.2-0.1-0.4-0.50.50.8-0.4
Delay discounting water rate 24 sec1.62.27.50.71.5-1.51.9-1.41.91.6-1.8-0.90.90.4-0.21.32.3-1.71.71.7-1.82.7-0.6-0.1-1.71.71.3-0.3
Delay discounting water rate 6 sec1.01.45.2-0.40.3-0.30.7-1.61.70.5-0.6-1.21.2-0.40.80.32.2-1.61.60.3-0.42.31.40.6-1.81.80.40.2
Locomotor activity0.40.61.60.30.4-0.4-0.91.3-1.00.3-0.31.1-1.10.8-0.8-1.1-0.20.9-0.90.3-0.3-0.7-0.8-0.80.7-0.70.4-0.7
Locomotor testing distance0.30.50.90.60.8-0.8-0.11.0-0.70.7-0.71.0-1.00.9-0.9-0.40.20.4-0.30.6-0.7-0.1-1.0-0.70.5-0.50.7-0.6
Locomotor testing rearing0.00.10.6-0.4-0.00.0-0.5-0.20.10.00.00.1-0.10.10.1-0.80.3-0.30.50.0-0.10.50.20.1-0.20.20.0-0.1
Light reinforcement 10.50.93.4-1.4-0.90.9-0.2-1.21.0-0.70.7-1.41.4-1.11.20.0-0.1-1.01.1-0.70.70.91.91.0-0.60.6-0.60.6
Light reinforcement 20.10.10.4-0.6-0.10.1-0.60.20.10.00.10.1-0.10.0-0.0-0.6-0.10.00.1-0.1-0.0-0.10.4-0.00.3-0.30.1-0.3
Reaction time number correct2.73.88.5-2.9-2.42.40.2-1.60.7-2.42.2-1.51.5-2.82.80.71.6-1.11.0-2.32.21.31.82.9-0.50.5-2.42.7
Reaction time mean minus median0.40.56.20.20.2-0.2-0.60.8-0.60.3-0.10.6-0.60.3-0.70.2-2.50.5-0.10.00.0-1.10.5-0.60.3-0.30.4-0.9
Reaction time mean minus median AUC0.40.59.4-0.3-0.10.1-0.20.1-0.10.10.1-0.00.0-0.2-0.10.6-3.1-0.20.7-0.20.2-0.70.8-0.1-0.40.40.2-0.6
Reaction time num false alarms1.31.73.61.91.7-1.71.0-0.21.11.9-1.9-0.50.51.3-1.01.1-1.3-0.80.91.7-1.71.2-0.1-1.4-0.90.91.9-1.6
Reaction time num false alarms AUC0.91.33.21.81.4-1.41.2-0.20.81.5-1.6-0.50.51.0-0.81.3-1.4-0.70.81.3-1.41.1-0.3-1.0-0.90.91.5-1.1
Reaction time trials correct on left2.73.88.5-2.9-2.42.40.2-1.60.7-2.42.2-1.51.5-2.82.80.71.6-1.11.0-2.32.21.31.82.9-0.50.5-2.42.7
Reaction time trials on left2.63.78.0-2.8-2.32.30.3-1.60.7-2.32.1-1.61.6-2.72.80.81.4-1.21.0-2.22.11.41.82.8-0.60.6-2.32.7
Reaction time mean0.50.72.20.60.8-0.8-1.10.7-0.60.9-0.70.9-0.91.0-1.0-0.9-1.00.40.10.6-0.6-0.70.6-1.10.4-0.41.0-1.5
Reaction time mean AUC0.81.02.90.91.1-1.1-1.10.9-0.81.1-0.91.1-1.11.3-1.3-1.1-0.90.6-0.10.8-0.9-0.80.2-1.40.5-0.51.3-1.7
Median of all reaction times0.30.51.50.60.6-0.6-1.10.3-0.50.7-0.60.6-0.60.9-0.7-1.2-0.00.20.20.5-0.5-0.30.9-0.90.3-0.30.9-1.2
Reaction time omissions0.30.41.00.60.8-0.80.6-0.30.50.8-0.8-0.20.20.2-0.40.8-1.0-0.60.80.6-0.70.5-0.0-0.3-0.80.80.8-0.6
Reaction time false alarm rate2.73.910.63.32.7-2.71.20.60.62.8-2.80.3-0.32.5-2.20.9-2.0-0.20.32.6-2.60.5-1.4-2.5-0.60.62.8-2.5
Reaction time premature initiation rate1.11.42.3-1.2-1.11.11.0-1.41.2-1.00.9-1.41.4-1.51.41.40.2-1.21.1-1.01.00.81.21.5-1.41.4-1.01.3
Reaction time premature initiations3.24.68.6-2.6-2.32.31.2-2.31.6-2.11.9-2.22.2-2.92.81.90.7-1.81.7-2.22.11.42.12.9-1.81.8-2.22.6
Std. dev. reaction times0.30.44.40.30.3-0.3-0.60.5-0.40.4-0.30.5-0.50.4-0.5-0.0-2.10.20.20.1-0.1-0.70.4-0.70.1-0.10.6-1.0
Reaction time trials completed2.63.78.0-2.8-2.32.30.3-1.60.7-2.32.1-1.61.6-2.72.80.81.4-1.21.0-2.22.11.41.82.8-0.60.6-2.32.7
Reaction time trials AUC2.53.67.9-2.8-2.42.40.1-1.60.6-2.32.1-1.51.5-2.72.80.61.2-1.11.0-2.22.21.31.92.7-0.50.5-2.32.5
Social response proportion4.44.710.0-3.1-3.03.0-0.3-1.3-0.0-2.92.8-1.61.6-3.22.90.4-1.3-0.70.6-3.02.90.02.13.0-0.40.4-2.92.7
Social responses0.20.24.3-0.3-0.20.20.20.1-0.3-0.20.2-0.20.2-0.40.20.4-2.1-0.00.0-0.40.4-0.2-0.40.3-0.30.3-0.20.2
Social time0.70.91.8-1.2-1.21.2-0.1-0.40.1-1.11.1-0.90.9-1.41.10.7-1.1-0.40.3-1.31.2-0.21.21.2-0.30.3-1.11.0
Conditioned locomotion1.41.75.00.70.6-0.62.2-1.51.70.7-0.9-1.51.5-0.00.22.2-1.1-1.81.81.1-1.01.40.20.1-2.02.00.6-0.0
Cocaine response after cond. corrected0.00.00.2-0.00.0-0.0-0.1-0.0-0.1-0.0-0.00.1-0.1-0.10.00.10.20.1-0.1-0.10.20.20.50.00.1-0.10.00.0
Cocaine response after cond. not corrected0.40.51.2-0.8-0.80.8-0.80.3-0.8-0.90.90.2-0.2-0.60.5-0.70.30.6-0.7-1.01.1-0.50.60.60.8-0.8-0.80.7
Cocaine response before conditioning0.81.01.9-1.1-1.21.2-1.20.6-1.1-1.31.40.2-0.2-0.70.6-1.20.10.9-0.9-1.41.3-1.10.10.71.0-1.0-1.30.9
Saline control response1.52.03.6-1.5-1.91.90.4-1.40.5-1.81.7-1.41.4-1.91.90.9-1.5-0.80.7-1.61.60.41.01.7-0.70.7-1.81.7
Condit. Reinf. active minus inactive responses1.21.54.6-1.5-1.51.5-1.50.4-1.0-1.61.60.3-0.3-1.00.9-1.42.10.7-0.6-1.71.6-0.71.01.11.2-1.2-1.51.2
Condit. Reinf. active-inactive response ratio0.70.74.2-0.30.0-0.0-1.31.0-1.0-0.10.20.9-0.90.3-0.4-1.42.00.9-0.8-0.30.2-0.80.5-0.21.2-1.2-0.0-0.2
Condit. Reinf. active responses2.33.27.0-2.5-2.52.5-1.2-0.4-0.6-2.62.6-0.40.4-2.22.1-0.81.50.2-0.3-2.62.5-0.51.22.20.8-0.8-2.62.3
Condit. Reinf. inactive responses2.12.75.8-2.2-2.42.4-0.4-0.9-0.1-2.42.4-0.80.8-2.32.10.2-0.6-0.20.1-2.42.3-0.40.72.10.0-0.0-2.42.2
Condit. Reinf. lever presses0.81.02.8-1.0-1.41.4-1.40.1-0.6-1.31.50.1-0.1-0.81.0-0.91.10.4-0.3-1.51.4-0.61.70.80.8-0.8-1.20.7
Condit. Reinf. lever reinforcers received2.33.37.1-2.5-2.62.6-1.0-0.5-0.5-2.72.6-0.60.6-2.32.2-0.71.40.1-0.2-2.72.6-0.41.22.30.7-0.7-2.72.4
Pavlov. Cond. lever latency0.91.22.3-1.4-1.11.10.9-1.30.8-1.00.8-1.31.3-1.51.21.0-1.4-1.00.8-0.91.00.40.01.5-0.90.9-1.11.4
Pavlov. Cond. magazine entry latency0.10.11.11.00.4-0.40.20.20.10.4-0.40.2-0.20.6-0.3-0.10.60.1-0.10.4-0.40.2-0.3-0.5-0.00.00.3-0.1
Pavlov. Cond. change in total contacts0.10.10.30.40.1-0.1-0.60.4-0.30.10.00.3-0.30.4-0.2-0.50.50.3-0.20.0-0.1-0.10.6-0.40.4-0.40.1-0.4
Pavlov. Cond. index score0.50.61.41.20.8-0.8-0.51.0-0.60.7-0.60.9-0.91.1-1.0-0.60.90.7-0.60.7-0.7-0.4-0.2-1.10.6-0.60.7-0.9
Pavlov. Cond. latency score1.01.32.71.61.2-1.3-0.51.3-0.71.1-1.01.3-1.31.6-1.5-0.80.91.0-0.81.1-1.1-0.5-0.6-1.50.8-0.81.2-1.3
Pavlov. Cond. lever contacts0.20.31.70.80.4-0.4-0.60.6-0.30.4-0.30.5-0.50.8-0.4-0.61.30.4-0.20.4-0.50.10.6-0.70.4-0.40.5-0.7
Pavlov. Cond. magazine entry number0.10.20.7-0.10.4-0.40.2-0.20.40.5-0.5-0.20.20.1-0.20.3-0.8-0.30.30.5-0.40.3-0.0-0.3-0.40.40.6-0.6
Pavlov. Cond. intertrial magazine entries0.20.31.1-0.7-0.40.40.2-0.50.5-0.30.3-0.50.5-0.60.60.6-0.2-0.60.7-0.30.40.51.10.5-0.50.5-0.30.3
Pavlov. Cond. lever-magazine prob. diff.0.30.31.11.00.6-0.6-0.30.7-0.30.6-0.50.6-0.60.9-0.7-0.40.80.4-0.30.6-0.6-0.10.2-0.80.4-0.40.6-0.7
Pavlov. Cond. response bias0.10.21.90.50.0-0.0-0.40.3-0.20.00.10.3-0.30.4-0.1-0.51.40.3-0.10.0-0.10.10.5-0.30.4-0.4-0.0-0.1
Conditioned reinforcement - actives2.52.55.41.61.7-1.7-0.21.7-1.21.5-1.42.0-2.01.8-2.1-0.1-1.01.4-1.41.4-1.4-1.3-2.3-2.01.0-1.01.6-1.9
Conditioned reinforcement - inactives2.32.66.8-0.00.2-0.2-2.42.0-2.6-0.00.32.5-2.50.9-1.3-2.00.72.2-2.0-0.30.3-2.2-0.7-1.22.4-2.40.4-1.2
Conditioned locomotion1.92.37.21.32.0-2.0-0.60.30.32.0-1.90.9-0.92.0-1.9-1.02.70.20.21.9-1.80.1-1.1-2.00.0-0.02.2-2.3
Intermittent access intake day 1-15 change1.61.510.31.81.5-1.50.30.30.31.4-1.40.6-0.61.6-1.4-0.43.20.2-0.21.6-1.60.1-1.2-1.2-0.00.01.3-0.8
Intermittent access intake escalation1.41.314.41.41.2-1.20.30.10.41.1-1.20.4-0.41.3-1.2-0.73.80.1-0.31.4-1.40.1-1.2-0.8-0.10.11.1-0.5
Intermittent access intake escalation 20.70.77.40.30.5-0.51.0-0.91.10.4-0.6-0.50.50.1-0.10.52.7-0.80.50.8-0.80.9-0.20.3-0.90.90.40.4
Intermitt. access day 1 inactive lever presses1.81.95.90.40.4-0.4-1.51.7-2.00.2-0.12.1-2.10.8-1.4-1.50.81.6-1.40.2-0.2-2.0-1.4-0.92.4-2.40.3-0.7
Intermitt. access day 15 inactive lever presses0.50.51.50.50.7-0.7-1.00.5-0.60.7-0.60.8-0.80.8-0.8-1.21.20.4-0.20.7-0.7-0.40.4-0.80.5-0.50.8-1.0
Intermitt. access escalation Index0.90.82.30.81.3-1.30.90.10.61.3-1.4-0.20.20.9-0.90.10.3-0.40.31.5-1.50.4-0.8-0.6-0.90.91.1-0.8
Intermittent access day 1 total infusions3.84.311.7-0.9-0.80.8-3.32.3-3.4-1.01.32.4-2.40.3-0.7-3.21.12.8-2.7-1.61.6-3.2-1.0-0.63.1-3.1-1.0-0.3
Intermittent access day 15 total infusions3.53.915.20.90.9-0.9-2.32.0-2.30.7-0.62.5-2.51.8-2.0-3.13.92.3-2.30.5-0.5-2.3-2.1-1.72.3-2.30.7-1.3
Intermittent access terminal intake (last 3 days)2.32.58.20.60.6-0.6-2.21.7-2.20.4-0.32.0-2.01.4-1.5-2.72.91.9-1.80.2-0.2-2.0-1.1-1.31.8-1.80.5-1.1
Intermittent access total infusions1.92.16.7-0.0-0.10.1-2.51.6-2.4-0.20.41.8-1.80.7-0.9-2.61.61.9-1.8-0.60.6-2.1-0.7-0.82.0-2.0-0.2-0.6
Intermittent access day 1 locomotion2.52.66.6-0.2-0.70.7-2.51.6-2.6-0.81.01.8-1.80.4-0.6-2.51.12.2-2.1-1.21.2-2.5-1.1-0.72.5-2.5-0.7-0.2
Intermittent access day 15 total locomotion2.12.221.6-1.0-0.70.7-1.90.5-1.5-0.91.01.1-1.1-0.2-0.2-2.14.71.3-1.3-1.11.1-1.7-0.70.31.8-1.8-0.90.6
Intermittent access total locomotion3.64.011.5-0.4-0.40.4-3.22.0-3.0-0.60.92.4-2.40.8-1.1-3.43.02.5-2.4-0.91.0-2.9-1.3-0.82.9-2.9-0.4-0.4
Intermittent access standard deviation0.50.54.50.1-0.10.1-1.00.4-0.9-0.20.20.6-0.60.2-0.1-1.22.10.5-0.4-0.30.3-0.40.5-0.11.1-1.1-0.20.1
Cocaine induced anxiety1.82.06.81.21.0-1.0-0.41.8-1.30.9-0.82.0-2.01.4-1.6-0.5-2.61.6-1.70.9-0.9-1.7-2.0-1.61.2-1.20.8-1.3
Post-drug Anxiety0.40.53.90.50.4-0.41.4-0.20.90.4-0.5-0.30.30.1-0.11.1-2.0-0.50.10.6-0.60.6-0.60.0-0.80.80.30.1
Baseline Anxiety5.55.811.1-1.4-1.41.42.3-3.12.8-1.30.9-3.33.3-2.42.72.12.3-3.02.9-0.90.93.32.72.8-2.82.8-1.32.6
Lifetime Intake1.61.85.6-0.1-0.20.2-2.11.5-2.2-0.30.51.7-1.70.6-0.8-2.42.01.8-1.7-0.60.6-1.9-0.7-0.61.7-1.7-0.3-0.3
Incentive Sensitization - Responses0.10.11.4-0.20.1-0.1-0.7-0.20.20.2-0.10.0-0.00.20.0-0.71.20.0-0.0-0.00.00.10.6-0.2-0.10.10.1-0.4
Incentive Sensitization - Breakpoint0.20.21.7-0.10.2-0.2-0.8-0.00.10.3-0.20.2-0.20.3-0.1-0.81.30.2-0.20.0-0.0-0.10.4-0.30.0-0.00.2-0.5
Progressive ratio test 1 active lever presses0.30.30.90.50.3-0.3-0.80.5-0.80.3-0.20.6-0.60.7-0.6-0.5-0.80.5-0.30.2-0.2-0.6-0.1-0.90.2-0.20.5-0.9
Progressive ratio test 1 breakpoint0.30.30.90.40.2-0.2-0.70.4-0.80.3-0.10.6-0.60.7-0.5-0.4-1.00.5-0.30.2-0.2-0.5-0.1-0.90.2-0.20.5-0.9
Progressive ratio test 1 inactive lever presses2.32.55.71.41.1-1.1-1.32.0-2.20.8-0.72.4-2.41.7-1.9-1.2-0.31.9-1.70.7-0.7-1.9-1.4-1.81.9-1.91.1-1.5
Progressive ratio test 2 active lever presses0.70.82.40.20.4-0.4-1.50.8-0.90.4-0.21.0-1.01.0-0.8-1.51.21.0-0.90.1-0.1-0.8-0.3-1.10.9-0.90.5-1.1
Progressive ratio test 2 breakpoint1.31.43.80.91.3-1.3-1.21.0-0.81.3-1.11.3-1.31.7-1.5-1.30.70.9-0.81.0-1.0-0.7-0.7-1.80.6-0.61.4-2.0
Progressive ratio test 2 inactive lever presses3.43.98.50.50.9-0.9-2.62.2-2.60.6-0.42.9-2.91.7-2.1-2.92.32.5-2.50.4-0.4-2.4-1.7-1.72.5-2.50.9-1.6
Total sessions with >9 infusions1.01.12.20.80.6-0.6-1.31.2-1.20.6-0.41.2-1.21.3-1.2-1.4-0.91.3-1.10.4-0.4-1.4-0.7-1.50.9-0.90.8-1.4
Short access day 1 total inactive lever presses1.41.66.6-0.6-0.60.6-1.91.5-1.9-0.70.91.4-1.40.1-0.6-1.7-0.61.7-1.5-0.90.9-2.6-0.3-0.31.6-1.6-0.5-0.3
Short access day 10 total inactive lever presses2.12.36.3-1.5-1.21.2-2.21.0-1.9-1.31.51.4-1.4-0.80.1-2.11.31.5-1.4-1.61.6-2.00.00.62.5-2.5-1.30.6
Short access day 1 total infusions0.80.83.4-0.4-0.30.3-1.50.9-1.4-0.40.61.2-1.20.4-0.5-1.80.41.2-1.1-0.50.5-1.6-0.3-0.41.0-1.0-0.1-0.4
Short access day 10 total infusions2.22.55.4-1.0-1.51.5-1.81.2-2.2-1.61.61.0-1.0-0.60.5-2.12.31.7-1.7-1.91.9-1.9-0.40.71.8-1.8-1.91.3
Short access total infusions0.91.03.10.2-0.20.2-1.31.2-1.8-0.40.51.2-1.20.5-0.6-1.71.11.5-1.4-0.50.4-1.6-0.7-0.41.1-1.1-0.3-0.0
Short access day 1 locomotion0.40.43.40.50.1-0.1-1.40.3-0.50.3-0.10.6-0.61.0-0.3-1.80.90.5-0.10.2-0.2-0.60.3-0.90.0-0.00.4-1.0
Short access day 10 total locomotion2.52.74.7-1.4-1.81.8-1.60.9-1.9-2.12.10.8-0.8-1.00.5-1.81.81.4-1.7-2.12.1-2.2-0.81.02.1-2.1-1.81.6
Short access total locomotion0.60.72.0-0.2-0.60.6-1.30.6-1.4-0.70.80.8-0.80.1-0.0-1.40.71.0-0.9-0.70.7-1.1-0.3-0.21.1-1.1-0.50.1
Compulsive drug intake1.01.03.40.70.6-0.61.7-1.01.60.6-0.7-0.90.9-0.20.31.80.0-1.21.30.8-0.91.70.40.2-1.21.20.50.1
One hour access (0.3 mA shock)2.32.617.50.10.5-0.5-2.41.6-1.80.3-0.12.0-2.01.2-1.3-2.74.21.7-1.60.1-0.1-1.3-0.8-1.12.0-2.00.5-1.0
One hour access (shock baseline)2.22.66.7-0.20.4-0.4-2.21.9-2.30.3-0.12.1-2.11.1-1.5-2.62.31.9-2.00.0-0.0-2.1-1.5-1.22.0-2.00.4-1.1
Number of responses in last shaping day0.40.41.00.80.6-0.6-0.30.8-0.50.4-0.40.7-0.71.0-0.8-0.60.80.4-0.20.5-0.5-0.3-0.1-0.80.0-0.00.8-0.8
Context. condit. distance diff. score0.60.82.00.71.1-1.1-0.40.9-0.41.1-1.00.9-0.91.1-1.2-0.4-0.00.6-0.51.0-1.0-0.2-0.5-1.20.4-0.41.2-1.4
Locomotion velocity, session 10.10.20.4-0.5-0.50.5-0.30.1-0.3-0.50.50.0-0.0-0.50.3-0.20.2-0.10.2-0.50.5-0.30.60.50.2-0.2-0.50.5
Locomotion distance, session 12.02.66.20.60.4-0.4-1.72.3-2.50.10.02.4-2.41.1-1.5-1.81.52.3-2.3-0.00.0-2.0-1.4-1.12.3-2.30.2-0.6
Locomotion velocity, session 20.20.31.71.00.5-0.50.8-0.00.20.4-0.6-0.10.10.4-0.20.51.3-0.20.20.6-0.60.6-0.2-0.2-0.30.30.30.2
Locomotion distance, session 21.21.85.41.41.1-1.1-0.51.6-1.50.8-0.81.7-1.71.5-1.6-1.22.31.5-1.70.8-0.8-1.0-1.9-1.21.3-1.30.7-0.6
Locomotion velocity, session 32.12.54.51.61.2-1.2-1.22.0-1.71.0-0.82.1-2.11.9-2.0-1.70.51.9-1.80.8-0.8-1.8-2.1-1.81.5-1.51.0-1.4
Locomotion distance, session 30.30.31.70.30.5-0.50.10.8-0.70.3-0.40.8-0.80.4-0.7-0.30.60.6-0.70.4-0.4-0.4-1.3-0.30.5-0.50.2-0.1
Stereotopy head waving bouts, day 31.41.73.90.5-0.10.1-2.01.8-1.9-0.10.31.8-1.80.9-0.9-1.9-0.31.9-1.7-0.30.3-1.8-0.7-1.11.9-1.90.1-0.9
Stereotopy head waving duration, day 31.82.25.4-0.4-0.60.6-2.31.9-2.3-0.70.91.8-1.80.3-0.6-2.20.52.1-2.0-0.90.9-2.3-0.5-0.42.2-2.2-0.6-0.3
Locomotion velocity, session 70.40.40.80.70.6-0.6-0.30.9-0.50.5-0.40.7-0.70.8-0.9-0.60.70.7-0.70.4-0.4-0.7-0.5-0.70.5-0.50.5-0.5
Locomotion distance, session 70.10.10.8-0.4-0.20.20.10.0-0.1-0.20.2-0.00.0-0.30.10.00.90.1-0.2-0.20.2-0.10.10.40.1-0.1-0.30.4
Stereotopy head waving bouts, day 71.21.44.4-0.9-0.60.6-2.11.4-1.7-0.70.91.4-1.40.0-0.2-2.1-0.61.5-1.3-0.90.9-1.40.1-0.21.7-1.7-0.5-0.3
Stereotopy head waving duration, day 70.80.91.6-0.8-1.11.1-1.20.6-1.2-1.21.30.6-0.6-0.60.5-1.20.20.9-1.0-1.31.3-0.90.10.61.2-1.2-1.20.8
Locomotion velocity, session 80.20.30.5-0.4-0.70.70.1-0.2-0.2-0.70.7-0.30.3-0.70.60.5-0.5-0.0-0.0-0.70.7-0.10.30.6-0.10.1-0.70.7
Locomotion distance, session 82.94.38.22.32.4-2.4-0.72.4-1.62.2-2.12.3-2.32.7-2.9-1.31.01.9-1.92.1-2.1-1.2-2.4-2.61.4-1.42.2-2.4
Degree of sensitization distance0.20.21.1-0.5-0.60.6-0.2-0.40.2-0.50.6-0.50.5-0.50.6-0.00.5-0.10.2-0.60.6-0.01.00.5-0.00.0-0.50.4
Degree of sensitization stereotypy0.30.31.0-0.7-0.50.5-1.00.5-0.7-0.50.60.5-0.5-0.30.2-1.0-0.40.5-0.5-0.60.6-0.30.30.20.7-0.7-0.40.1
Condit. Reinf. active minus inactive responses0.60.62.20.10.1-0.1-1.01.0-1.0-0.00.11.0-1.00.5-0.5-1.50.51.1-1.3-0.10.1-1.0-1.3-0.41.1-1.1-0.0-0.2
Condit. Reinf. active-inactive response ratio1.01.13.10.20.4-0.4-1.31.3-1.20.3-0.11.4-1.40.8-1.1-1.8-0.11.4-1.40.1-0.1-1.5-1.3-0.91.3-1.30.4-0.8
Condit. Reinf. active responses0.91.13.41.31.2-1.2-0.31.0-0.61.0-1.11.1-1.11.4-1.3-1.00.80.9-1.11.1-1.1-0.4-1.9-1.30.6-0.61.0-1.0
Condit. Reinf. inactive responses0.60.71.81.31.1-1.10.70.00.41.1-1.10.2-0.21.0-0.70.41.1-0.20.01.1-1.10.7-0.9-0.8-0.40.41.0-0.6
Incentive salience index mean1.01.23.90.90.6-0.6-0.81.4-1.30.4-0.41.4-1.41.0-1.1-1.51.51.4-1.70.4-0.4-1.0-2.0-0.91.3-1.30.4-0.4
Condit. Reinf. lever presses1.01.34.11.61.4-1.40.41.0-0.61.1-1.21.1-1.11.4-1.3-0.32.00.8-1.01.2-1.2-0.0-2.0-1.10.5-0.51.0-0.6
Time in familiar zone, hab. session 10.90.92.40.30.2-0.2-1.11.3-1.30.10.01.2-1.20.7-0.8-1.50.61.4-1.5-0.00.0-1.2-0.9-0.71.2-1.20.1-0.4
Time in novel zone, hab. session 10.60.53.20.10.1-0.10.6-0.80.90.3-0.3-0.60.6-0.10.31.2-1.8-1.01.30.3-0.30.81.0-0.0-0.90.90.3-0.4
Total zone transitions, hab. session 10.81.23.3-0.4-0.20.2-1.61.4-1.8-0.30.41.4-1.40.2-0.5-1.60.71.5-1.6-0.40.4-1.2-0.6-0.31.7-1.7-0.2-0.2
Total locomotion distance, hab. session 12.33.36.31.21.6-1.6-1.72.5-2.01.4-1.22.3-2.32.1-2.3-2.10.12.1-1.91.2-1.2-1.6-1.7-2.21.9-1.91.6-2.1
Locomotion velocity, hab. session 11.42.03.51.01.3-1.3-1.31.9-1.41.2-1.01.7-1.71.7-1.8-1.60.21.5-1.41.0-1.0-1.2-1.2-1.71.3-1.31.3-1.7
Time in familiar zone, hab. session 21.41.53.60.00.0-0.01.6-1.61.90.3-0.4-1.91.9-0.40.81.3-0.9-1.81.70.4-0.41.70.80.6-1.91.90.10.4
Time in novel zone, hab. session 20.80.82.0-0.1-0.40.4-1.31.0-1.4-0.50.71.3-1.30.1-0.3-0.8-0.11.3-1.2-0.70.7-1.3-0.1-0.31.4-1.4-0.4-0.2
Total zone transitions, hab. session 21.82.35.5-0.8-1.21.2-1.81.4-2.2-1.51.51.4-1.4-0.40.2-2.02.31.9-2.0-1.51.5-1.6-0.50.52.0-2.0-1.41.1
Total locomotion distance, hab. session 21.41.83.91.41.3-1.3-0.81.8-1.31.1-1.01.6-1.61.7-1.7-1.51.01.5-1.51.0-1.0-0.9-2.0-1.51.1-1.11.1-1.1
Locomotion velocity, hab. session 21.82.44.31.41.4-1.4-1.12.1-1.61.2-1.11.9-1.91.9-1.9-1.91.11.7-1.71.1-1.1-1.1-2.1-1.71.4-1.41.2-1.3
Novel to familiar place preference ratio1.01.02.3-1.4-1.51.5-0.3-0.60.1-1.51.5-0.60.6-1.31.00.10.5-0.0-0.0-1.51.5-0.70.81.30.3-0.3-1.51.3
Novelty place preference1.21.22.7-1.5-1.61.6-0.6-0.4-0.2-1.61.6-0.30.3-1.31.0-0.20.40.2-0.2-1.61.6-1.10.81.30.6-0.6-1.61.2
Time in novel zone, NPP test1.31.43.1-1.6-1.81.8-0.7-0.4-0.3-1.71.8-0.30.3-1.41.1-0.20.60.2-0.3-1.81.8-1.10.81.40.7-0.7-1.71.3
Total zone transitions, NPP test0.71.04.10.60.1-0.1-0.91.2-1.6-0.10.11.3-1.30.6-0.5-1.22.01.3-1.5-0.10.1-0.6-1.2-0.41.4-1.4-0.10.1
Total locomotion distance, NPP test1.82.55.12.21.9-1.9-0.41.5-0.91.7-1.71.6-1.62.2-2.0-1.10.91.2-1.21.7-1.7-0.3-2.0-2.10.8-0.81.7-1.7
Locomotion velocity, NPP test1.62.35.02.21.9-1.9-0.31.4-0.81.8-1.71.4-1.42.2-1.9-1.00.41.0-1.01.7-1.7-0.1-1.8-2.10.6-0.61.8-1.7
Pavlov. Cond. lever latency0.70.94.00.30.6-0.60.8-0.91.40.8-0.8-0.80.80.2-0.11.1-2.0-1.11.30.8-0.80.70.6-0.4-1.31.30.8-0.8
Pavlov. Cond. magazine entry latency0.20.33.2-0.3-0.40.4-0.30.1-0.4-0.50.50.2-0.2-0.30.3-0.51.80.3-0.5-0.50.50.0-0.30.50.4-0.4-0.60.8
Pavlov. Cond. change in total contacts1.21.33.41.10.9-0.9-0.61.4-1.10.7-0.71.4-1.41.2-1.1-1.11.81.3-1.50.7-0.7-0.3-1.9-1.01.1-1.10.7-0.5
Pavlov. Cond. index score0.40.56.4-0.1-0.00.0-0.30.7-0.8-0.20.10.7-0.70.1-0.1-0.82.50.7-0.9-0.10.1-0.1-0.80.20.8-0.8-0.30.6
Pavlov. Cond. latency score0.50.65.0-0.2-0.30.3-0.50.8-1.0-0.50.40.7-0.7-0.1-0.0-0.92.20.8-1.1-0.40.4-0.3-0.80.31.0-1.0-0.50.7
Pavlov. Cond. lever contacts0.60.84.7-0.0-0.20.2-0.71.0-1.3-0.50.41.0-1.00.1-0.2-0.92.21.1-1.3-0.40.4-0.7-0.80.11.2-1.2-0.50.6
Pavlov. Cond. magazine entry number0.50.66.10.80.6-0.6-0.30.5-0.20.6-0.50.4-0.40.8-0.9-0.0-2.50.4-0.10.5-0.5-1.0-0.0-1.00.1-0.10.8-1.3
Pavlov. Cond. intertrial magazine entries0.10.20.50.70.6-0.60.20.10.20.6-0.60.1-0.10.6-0.5-0.20.20.0-0.10.6-0.6-0.0-0.4-0.5-0.10.10.6-0.4
Pavlov. Cond. lever-magazine prob. diff.0.40.55.20.20.2-0.2-0.20.7-0.70.0-0.10.7-0.70.3-0.3-0.72.30.7-0.90.1-0.1-0.1-1.0-0.10.7-0.7-0.10.3
Pavlov. Cond. response bias0.40.47.4-0.1-0.00.0-0.10.4-0.6-0.20.10.5-0.5-0.00.0-0.62.70.4-0.7-0.10.10.2-0.70.30.5-0.5-0.30.6
Bone: apparent density1.82.95.7-1.0-1.61.6-2.41.1-1.9-1.81.91.4-1.4-0.50.3-2.41.92.0-2.1-1.92.0-2.4-0.20.52.2-2.2-1.70.9
Bone surface2.34.18.1-1.8-2.32.3-2.51.1-2.3-2.52.71.2-1.2-1.20.8-2.10.32.1-2.4-2.62.8-2.9-0.21.02.4-2.4-2.41.4
Bone volume2.03.38.1-0.9-1.51.5-2.61.5-2.2-1.71.91.7-1.7-0.4-0.0-2.51.42.3-2.5-1.82.0-2.8-0.50.22.5-2.5-1.60.7
Bone: connectivity density2.33.68.6-2.1-2.62.6-2.00.4-1.6-2.72.80.4-0.4-1.81.5-1.40.31.3-1.4-2.82.9-1.91.01.61.6-1.6-2.61.8
Bone: cortical apparent density0.81.02.50.2-0.30.31.3-1.31.3-0.10.0-1.41.4-0.60.91.6-1.4-1.31.4-0.0-0.11.40.70.5-1.31.3-0.20.6
Bone: cortical area2.13.27.82.82.4-2.40.41.2-0.12.3-2.31.3-1.32.5-2.40.0-0.50.7-0.72.3-2.1-0.3-2.3-2.50.1-0.12.3-2.2
Bone: cortical porosity0.70.72.0-1.1-1.01.0-0.2-0.0-0.5-1.21.1-0.00.0-0.90.7-0.51.40.3-0.6-1.01.0-0.5-0.71.10.6-0.6-1.31.3
Bone: cortical porosity0.60.72.1-1.0-1.01.00.4-0.70.3-1.10.9-0.70.7-1.01.00.11.3-0.50.2-0.80.80.2-0.21.2-0.10.1-1.21.4
Bone: cortical thickness2.13.47.72.82.2-2.22.1-0.71.92.4-2.5-0.60.61.8-1.31.9-1.4-1.21.42.5-2.41.6-0.9-1.8-1.81.82.3-1.7
Bone: cortical thickness0.80.93.41.10.9-0.90.8-0.51.01.1-1.0-0.50.50.7-0.41.1-1.8-0.70.91.1-0.91.00.2-0.9-1.01.01.1-1.1
Bone: cortical tissue density1.01.32.90.0-0.50.51.4-1.51.4-0.30.2-1.61.6-0.91.21.7-1.5-1.51.6-0.20.11.50.90.8-1.41.4-0.40.8
Bone: elastic displacement0.80.91.70.40.9-0.91.1-0.91.31.1-1.1-0.80.80.4-0.21.1-0.4-1.21.31.1-1.21.30.6-0.4-1.31.31.0-0.8
Bone: elastic work0.91.22.11.11.2-1.20.9-0.61.21.4-1.4-0.50.50.8-0.51.1-1.1-0.91.21.3-1.31.20.7-1.0-1.21.21.5-1.3
Bone: endosteal estimation2.35.010.91.01.0-1.0-2.23.1-2.90.7-0.53.1-3.11.9-2.3-2.81.73.1-3.30.5-0.3-2.7-3.0-1.82.9-2.90.8-1.3
Bone: endosteal perimeter2.34.812.30.20.3-0.4-2.53.0-3.1-0.10.23.0-3.01.2-1.8-3.01.53.2-3.5-0.20.4-3.0-2.7-1.23.1-3.10.1-0.7
Bone: final force0.81.24.52.11.4-1.40.10.60.11.4-1.40.6-0.61.7-1.30.0-0.00.5-0.51.4-1.20.1-1.3-1.70.0-0.01.4-1.4
Bone: final moment0.71.24.32.11.4-1.40.00.7-0.11.4-1.30.8-0.81.7-1.3-0.10.20.6-0.71.4-1.20.0-1.3-1.70.2-0.21.4-1.4
Bone: marrow area2.45.211.11.11.2-1.2-2.23.1-2.90.8-0.63.2-3.22.0-2.4-2.81.63.2-3.30.6-0.5-2.7-3.2-2.02.9-2.90.9-1.5
Bone: maximum diameter2.03.79.72.52.3-2.3-0.31.8-0.92.1-2.11.9-1.92.6-2.6-0.8-0.41.5-1.62.1-1.9-0.9-3.1-2.60.8-0.82.2-2.2
Bone: maximum force1.22.13.61.81.0-1.0-1.31.8-1.40.9-0.71.8-1.81.8-1.6-1.50.81.9-1.90.7-0.5-1.5-1.6-1.81.5-1.51.0-1.4
Bone: maximum moment1.22.23.71.81.1-1.1-1.31.8-1.40.9-0.81.9-1.91.9-1.7-1.50.91.9-1.90.8-0.6-1.4-1.6-1.81.5-1.51.0-1.4
Bone: minimum diameter2.95.411.81.91.6-1.6-1.93.2-2.61.1-1.13.1-3.12.5-2.7-2.61.53.1-3.11.0-0.8-2.5-3.4-2.32.7-2.71.2-1.7
Bone: periosteal estimation2.45.011.92.62.3-2.3-1.02.5-1.72.0-1.92.6-2.62.9-3.0-1.60.72.3-2.41.9-1.7-1.7-3.5-2.81.7-1.72.1-2.3
Bone: periosteal perimeter0.81.44.51.31.0-1.0-0.61.4-1.00.8-0.81.5-1.51.4-1.5-0.90.41.4-1.50.8-0.6-1.0-2.1-1.41.1-1.10.9-1.0
Bone: post-yield work4.76.416.30.3-0.20.2-3.23.3-3.6-0.60.83.3-3.31.2-1.5-3.72.83.8-4.0-0.80.9-3.4-2.3-1.13.7-3.7-0.5-0.3
Bone: stiffness1.21.84.21.50.7-0.7-1.01.7-1.50.4-0.41.7-1.71.5-1.4-1.51.31.9-2.00.5-0.3-1.5-2.1-1.31.6-1.60.5-0.6
Bone: tissue strength2.22.15.01.21.1-1.1-1.01.8-1.40.9-0.82.0-2.01.6-1.6-1.72.21.7-1.80.9-0.7-1.1-2.0-1.41.5-1.50.9-1.0
Bone: trabecular number1.82.85.4-1.5-1.91.9-1.80.7-1.7-2.12.10.9-0.9-1.10.8-1.81.71.5-1.8-2.22.3-1.9-0.11.21.8-1.8-2.11.6
Bone: trabecular spacing0.50.61.30.80.9-0.91.0-0.20.81.0-1.0-0.60.60.6-0.40.60.5-0.60.71.2-1.11.00.0-0.5-0.80.80.9-0.5
Bone: trabecular thickness1.41.64.1-0.5-0.70.7-2.01.1-1.6-0.91.01.5-1.5-0.0-0.2-2.01.51.6-1.7-1.11.1-1.9-0.3-0.01.8-1.8-0.70.2
Bone: trabecular tissue density1.92.65.42.02.1-2.10.11.4-0.52.0-2.01.5-1.52.1-2.2-0.50.80.9-0.92.0-2.1-0.2-2.3-2.00.7-0.71.9-1.8
Breakpoint value in progressive ratio session0.40.51.40.1-0.50.50.5-0.90.8-0.40.3-1.21.2-0.40.80.2-1.0-0.90.9-0.40.40.50.80.4-0.90.9-0.40.4
Distance traveled before self-admin0.10.10.30.00.4-0.4-0.30.10.10.4-0.40.2-0.20.4-0.2-0.6-0.20.1-0.00.2-0.20.30.2-0.3-0.30.30.5-0.6
Distance traveled after self-admin1.11.23.21.51.5-1.5-0.40.4-0.21.6-1.40.6-0.61.6-1.0-0.8-0.00.10.11.5-1.50.60.1-1.6-0.10.11.7-1.8
Delta time in closed arm before/after self-admin5.75.510.82.82.7-2.71.9-1.12.63.0-3.1-1.41.42.2-1.11.1-1.3-2.22.53.3-3.32.50.3-2.0-2.82.83.0-2.3
Delta time in open arm before/after self-admin1.31.28.7-0.9-1.51.4-1.0-1.00.1-1.41.4-0.10.1-0.81.3-0.73.0-0.1-0.1-1.31.30.51.10.80.4-0.4-1.31.0
Diff in mean of infusions in LGA sessions1.11.22.41.11.3-1.30.9-1.21.51.5-1.5-0.40.40.9-0.50.30.7-1.11.20.8-0.81.30.3-0.7-1.61.61.5-1.1
Extinction: sum of active levers before priming0.20.20.90.90.3-0.30.50.2-0.00.3-0.30.1-0.10.5-0.4-0.2-0.20.1-0.20.6-0.6-0.4-0.9-0.4-0.40.40.2-0.0
Active lever presses in extinction session 60.80.86.61.00.9-0.90.8-0.00.51.0-1.0-0.30.30.7-0.80.7-2.6-0.0-0.10.7-0.7-0.1-0.6-0.8-0.50.51.0-1.0
Delta distance traveled before/after self-admin0.20.20.70.80.5-0.5-0.2-0.1-0.20.5-0.50.1-0.10.6-0.3-0.20.7-0.10.10.6-0.60.3-0.0-0.70.2-0.20.5-0.5
Delta ambulatory time before/after self-admin0.20.20.80.90.5-0.50.20.4-0.70.3-0.30.5-0.50.5-0.40.0-0.30.3-0.40.6-0.6-0.0-0.7-0.60.6-0.60.3-0.4
Time in closed arm before self-admin0.50.51.4-0.1-0.30.3-1.11.1-0.9-0.40.50.9-0.9-0.0-0.3-0.5-0.61.2-1.1-0.40.4-1.00.1-0.31.2-1.2-0.3-0.2
Time in closed arm after self-admin2.22.35.82.22.1-2.10.10.60.82.2-2.10.2-0.21.9-1.6-0.1-1.4-0.10.62.1-2.10.50.0-2.1-0.40.42.3-2.4
Time in open arm before self-admin0.60.65.90.40.8-0.81.10.20.40.8-0.9-0.10.10.4-0.70.8-2.4-0.20.10.7-0.7-0.1-1.0-0.3-0.60.60.7-0.4
Time in open arm after self-admin0.20.20.5-0.5-0.60.6-0.2-0.60.2-0.50.50.1-0.1-0.20.5-0.00.7-0.20.1-0.70.70.40.40.20.0-0.0-0.40.3
Sum of active levers in priming session hrs 5-60.20.20.90.60.5-0.50.9-0.30.30.5-0.5-0.20.20.3-0.10.5-0.9-0.50.50.6-0.60.5-0.5-0.2-0.50.50.4-0.2
Time to tail flick, vehicle, before self-admin5.45.430.6-2.0-3.03.0-1.1-0.7-0.4-3.13.0-0.60.6-2.12.2-2.05.50.4-0.8-3.03.0-0.60.22.41.0-1.0-3.23.2
Time to tail flick, vehicle, after self-admin1.81.93.8-1.6-1.81.8-0.3-1.10.2-1.81.7-1.01.0-1.91.7-0.01.8-0.40.4-1.71.70.01.71.8-0.10.1-1.81.7
Time to tail flick, test, before self-admin1.01.02.8-0.4-1.01.0-1.40.8-1.2-1.21.20.9-0.9-0.20.3-1.70.71.0-1.2-0.80.8-1.0-0.10.21.6-1.6-1.10.7
Time to tail flick, test, after self-admin1.51.55.2-1.3-1.61.60.6-0.70.1-1.81.7-0.60.6-1.81.70.7-0.1-0.30.1-1.41.40.30.51.8-0.20.2-2.02.3
Delta time to tail flick, vehicle, before/after SA0.50.53.90.50.9-0.90.30.2-0.10.9-0.80.3-0.30.3-0.60.8-2.0-0.00.20.9-0.90.10.4-0.6-0.30.30.9-1.0
Delta time to tail flick, test, before/after SA2.62.48.8-0.0-0.10.12.7-1.92.20.0-0.3-1.81.8-1.11.13.0-0.1-2.01.90.2-0.22.10.51.2-2.32.3-0.31.1
Ambulatory time before self-admin1.21.23.01.21.5-1.5-0.51.0-0.21.6-1.50.9-0.91.6-1.5-0.8-0.40.6-0.41.2-1.2-0.3-0.6-1.50.2-0.21.6-1.7
Ambulatory time after self-admin1.31.42.71.01.1-1.1-1.31.2-1.31.0-0.91.5-1.51.4-1.2-1.71.21.0-0.91.0-1.0-0.4-0.6-1.41.4-1.41.1-1.5
Total heroin consumption1.51.85.2-1.0-2.02.00.8-1.00.6-2.01.8-1.01.0-1.71.80.8-0.3-0.50.2-1.61.60.20.21.7-0.50.5-2.12.3
Area under the delay curve1.81.94.3-2.1-2.12.0-0.8-0.3-0.4-2.02.0-0.30.3-1.71.6-0.81.20.0-0.0-1.91.9-0.41.01.70.4-0.4-2.11.7
Delay disc. indifference point, 0s delay1.61.84.2-1.6-1.71.7-2.00.7-1.3-1.61.70.6-0.6-1.01.0-1.60.61.0-0.9-1.91.9-1.00.90.81.4-1.4-1.60.7
Delay disc. indifference point, 16s delay1.31.43.3-1.8-1.61.6-1.3-0.2-0.4-1.51.60.1-0.1-1.11.2-1.41.50.1-0.1-1.51.5-0.31.41.10.7-0.7-1.51.1
Delay disc. indifference point, 2s delay1.01.13.2-1.8-1.51.5-0.9-0.4-0.4-1.41.4-0.40.4-1.41.2-0.61.2-0.20.1-1.51.50.01.11.20.3-0.3-1.30.9
Delay disc. indifference point, 24s delay1.41.43.9-0.8-0.40.41.2-2.01.6-0.20.1-1.51.5-1.01.21.40.6-1.81.9-0.10.01.71.31.1-1.31.3-0.40.8
Delay disc. indifference point, 4s delay1.92.03.9-1.6-1.91.9-0.2-1.00.5-1.81.8-1.11.1-1.61.8-0.32.0-0.80.9-1.51.50.31.51.7-0.50.5-1.81.8
Delay disc. indifference point, 8s delay0.50.51.4-1.2-0.90.90.10.2-0.3-1.00.90.0-0.0-1.00.70.0-0.90.2-0.4-1.01.0-0.5-0.51.00.0-0.0-1.21.1
Delay discount exponential model param1.92.04.42.12.1-2.10.60.60.12.0-2.00.5-0.51.8-1.70.5-1.10.2-0.21.9-1.90.2-1.1-1.8-0.10.12.1-1.8
Delay discount hyperbolic model param2.22.35.02.22.2-2.20.70.60.12.2-2.20.6-0.61.9-1.80.6-1.20.2-0.22.1-2.10.2-1.3-1.9-0.10.12.2-1.9
Fecal boli incidents, locomotor time 10.60.61.1-0.8-0.80.8-0.70.4-0.7-1.01.00.8-0.8-0.80.4-0.40.60.8-1.0-0.90.9-0.5-0.60.71.0-1.0-0.80.8
Change in fecal boli incidents, locomotor task0.50.51.70.1-0.00.00.9-0.91.30.2-0.3-1.01.0-0.20.41.1-0.8-1.11.20.1-0.10.70.50.2-0.90.9-0.10.1
Time >=10cm from walls, locomotor time 13.63.68.51.41.2-1.2-1.72.5-2.20.9-0.72.9-2.91.7-2.1-2.11.52.5-2.40.5-0.5-2.1-2.0-1.82.4-2.40.9-1.3
Bouts of movement, locomotor time 11.01.22.5-0.6-0.70.71.1-1.41.6-0.40.2-1.51.5-1.21.31.5-0.4-1.21.2-0.70.71.20.91.2-1.11.1-0.81.0
Total resting periods, locomotor time 11.11.22.4-0.9-0.80.80.8-1.51.5-0.60.4-1.41.4-1.31.31.20.8-1.21.3-0.80.81.21.31.2-1.01.0-0.91.0
Rest time, locomotor task time 10.40.44.3-0.5-0.20.20.5-0.70.9-0.10.1-0.50.5-0.40.50.52.1-0.70.8-0.10.00.7-0.20.5-0.40.4-0.30.5
Distance moved, locomotor task time 10.30.31.10.00.0-0.0-0.20.6-0.6-0.20.10.5-0.50.2-0.4-1.01.10.7-1.0-0.10.2-0.7-1.00.10.6-0.6-0.20.3
Vertical activity count, locomotor time 10.70.71.30.40.9-0.9-0.41.1-0.60.8-0.90.9-0.90.9-1.1-0.8-1.00.8-1.10.7-0.7-0.4-1.1-0.90.7-0.70.9-0.9
Time >=10cm from walls, locomotor time 20.80.82.91.21.3-1.30.90.50.41.2-1.30.5-0.50.9-1.10.41.50.2-0.31.0-1.00.2-1.7-0.70.1-0.10.9-0.5
Bouts of movement, locomotor time 23.23.58.5-1.1-0.90.91.4-2.92.5-0.60.5-2.42.4-1.62.11.20.9-2.62.8-0.50.52.62.81.8-2.32.3-0.71.4
Total resting periods, locomotor time 21.92.15.6-0.5-0.40.41.1-2.32.0-0.20.1-1.91.9-1.01.50.90.7-2.12.4-0.10.12.22.21.2-1.91.9-0.20.8
Rest time, locomotor task time 20.40.42.2-0.3-0.40.4-1.20.6-0.8-0.40.40.8-0.80.2-0.2-1.51.20.5-0.2-0.20.1-0.9-0.3-0.20.9-0.9-0.30.0
Distance moved, locomotor task time 20.20.21.5-0.10.1-0.11.2-0.00.2-0.1-0.1-0.20.2-0.40.21.00.50.0-0.5-0.10.10.4-1.20.5-0.20.2-0.30.8
Vertical activity count, locomotor time 20.80.83.00.71.1-1.11.70.10.61.0-1.1-0.00.00.3-0.51.7-1.5-0.3-0.11.0-1.00.9-1.5-0.3-0.70.70.8-0.1
Weight adjusted by age0.40.41.4-0.9-0.60.60.3-0.80.1-0.70.5-0.20.2-1.20.70.50.3-0.40.2-0.60.60.70.01.20.2-0.2-0.81.2
Seeking ratio, delayed vs. immediate footshock0.40.51.80.1-0.50.5-0.1-1.01.0-0.20.2-1.11.1-0.10.7-0.01.1-0.81.1-0.20.30.81.40.2-0.60.6-0.10.1
Locomotion in novel chamber1.62.05.0-0.5-0.10.1-1.91.9-2.2-0.30.41.8-1.80.4-0.9-2.21.61.9-1.8-0.40.4-2.2-1.2-0.42.0-2.0-0.2-0.4
Locomotion in novel chamber post-restriction1.21.53.70.31.0-1.0-1.31.5-1.20.9-0.71.9-1.91.0-1.5-1.20.71.3-1.10.7-0.8-1.3-1.0-1.21.4-1.40.9-1.4
Progressive ratio1.31.53.7-0.8-1.81.8-1.20.4-0.9-1.81.9-0.20.2-0.90.9-1.20.60.8-0.8-1.91.9-1.60.60.80.7-0.7-1.71.2
Food seeking constrained by brief footshock0.30.40.9-0.4-0.60.60.4-0.20.1-0.70.6-0.70.7-0.60.90.5-0.8-0.30.2-0.60.50.30.80.7-0.90.9-0.70.8
Seeking ratio, punishment vs. effort0.81.03.80.41.1-1.11.1-0.71.01.2-1.3-0.40.40.4-0.01.2-0.7-1.11.01.2-1.32.00.4-0.3-1.21.21.1-0.6
Run reversals in cocaine runway, females0.20.21.00.4-0.30.3-0.50.0-0.5-0.40.40.4-0.40.10.5-0.20.90.2-0.2-0.30.20.51.0-0.20.5-0.5-0.30.1
Run reversals in cocaine runway, males2.92.816.92.21.9-1.90.50.70.12.0-1.90.5-0.52.0-1.80.7-4.10.10.11.9-1.9-0.3-0.5-2.2-0.70.72.2-2.4
Latency to leave start box in cocaine runway0.10.10.7-0.00.2-0.2-0.70.3-0.10.3-0.2-0.10.10.4-0.3-0.8-0.10.2-0.00.0-0.0-0.30.6-0.4-0.10.10.4-0.7
Latency to leave start box in cocaine runway, F0.10.11.6-0.00.2-0.2-0.40.10.20.3-0.2-0.20.20.2-0.1-0.3-1.3-0.1-0.00.1-0.1-0.00.7-0.3-0.20.20.5-0.7
Latency to leave start box in cocaine runway, M0.50.51.40.60.6-0.6-0.30.9-0.90.5-0.40.8-0.80.8-1.0-0.60.40.9-0.70.4-0.4-1.0-1.2-0.70.5-0.50.5-0.6
Cd content in liver0.10.11.1-0.4-0.00.0-0.40.0-0.4-0.00.10.2-0.2-0.1-0.2-0.3-1.10.1-0.1-0.10.1-0.40.2-0.10.3-0.30.1-0.4
Co content in liver0.70.82.60.40.5-0.51.6-0.71.10.5-0.7-1.01.0-0.10.21.4-0.2-1.21.10.7-0.71.40.10.2-1.41.40.40.2
Cu content in liver0.70.91.91.11.4-1.40.70.40.21.3-1.40.3-0.31.1-1.30.3-0.3-0.10.11.4-1.4-0.0-1.2-1.0-0.30.31.3-1.0
Fe content in liver0.70.81.60.90.8-0.8-0.81.1-0.60.8-0.70.9-0.91.1-1.2-0.8-0.80.9-0.80.7-0.7-0.8-0.7-1.30.7-0.70.9-1.3
K content in liver1.01.03.50.2-0.00.0-1.01.4-1.5-0.20.31.3-1.30.5-0.9-1.11.01.5-1.4-0.30.3-1.9-0.9-0.51.5-1.5-0.2-0.2
Mg content in liver2.52.58.0-0.6-0.60.6-2.52.1-2.4-0.81.02.0-2.00.2-0.8-2.0-0.02.3-2.1-1.01.0-2.80.1-0.52.4-2.4-0.6-0.5
Mn content in liver0.40.45.4-0.2-0.40.40.5-0.30.1-0.60.4-0.20.2-0.40.20.12.3-0.10.0-0.40.4-0.3-0.60.80.0-0.0-0.81.2
Na content in liver0.20.21.0-0.10.7-0.70.10.20.20.6-0.60.3-0.30.3-0.6-0.10.10.0-0.10.6-0.60.1-1.0-0.40.1-0.10.6-0.5
Rb content in liver1.01.37.0-0.5-0.60.6-1.41.3-1.7-0.70.91.2-1.2-0.0-0.7-1.2-0.51.5-1.5-0.90.9-2.6-0.7-0.11.5-1.5-0.6-0.1
Se content in liver1.31.63.0-1.3-1.11.1-1.50.9-1.7-1.31.31.0-1.0-0.70.3-1.51.71.4-1.5-1.31.3-1.2-0.10.71.7-1.7-1.30.8
Sr content in liver1.11.02.3-0.2-0.40.41.5-1.21.3-0.40.2-1.41.4-0.91.21.4-0.4-1.31.2-0.20.21.50.21.1-1.31.3-0.51.2
Zn content in liver0.70.82.51.31.2-1.20.40.60.11.2-1.20.2-0.21.1-1.00.4-1.60.00.11.2-1.20.2-0.1-1.2-0.30.31.3-1.3