Hub : Genes

Tkfc

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000020704 0.49 0.11 2.2e-12 0.05 0.1 0.1 0.09 2.6e-06 1.0e-10 8.3e-11 2.9e-10
2 Adipose mRNA stability ENSRNOG00000020704 0.41 0.1 0.0e+00 0.23 0.27 0.26 0.24 1.9e-25 4.9e-30 7.4e-29 3.1e-26
3 BLA mRNA stability ENSRNOG00000020704 0.2 0.09 2.7e-10 0.17 0.16 0.16 0.16 1.4e-09 1.1e-08 1.1e-08 7.1e-09
4 Brain mRNA stability ENSRNOG00000020704 0.22 0.09 0.0e+00 0.2 0.23 0.23 0.23 3.8e-18 4.2e-21 5.9e-21 5.9e-21
5 Eye mRNA stability ENSRNOG00000020704 0.6 0.15 2.9e-04 0.13 0.03 0.01 0.06 5.3e-03 1.2e-01 2.0e-01 4.3e-02
6 IL mRNA stability ENSRNOG00000020704 0.25 0.16 1.6e-03 0.04 0.07 0.1 0.04 4.3e-02 7.9e-03 2.6e-03 3.9e-02
7 LHb mRNA stability ENSRNOG00000020704 0.16 0.09 4.2e-03 0.02 0.03 0.04 0.02 1.0e-01 5.9e-02 5.2e-02 1.3e-01
8 Liver gene expression ENSRNOG00000020704 0.07 0.06 1.2e-03 0 0.02 0.01 0.01 3.3e-01 4.0e-03 1.9e-02 6.3e-02
9 Liver mRNA stability ENSRNOG00000020704 0.23 0.09 0.0e+00 0.1 0.13 0.13 0.13 1.1e-11 1.9e-14 1.1e-14 1.3e-14
10 NAcc mRNA stability ENSRNOG00000020704 0.41 0.13 2.2e-11 0.1 0.13 0.15 0.11 5.6e-08 5.3e-10 5.2e-11 2.8e-08
11 OFC mRNA stability ENSRNOG00000020704 0.16 0.09 9.4e-04 0.05 0.04 0.06 0.06 2.2e-02 3.4e-02 1.8e-02 1.6e-02
12 PL mRNA stability ENSRNOG00000020704 0.27 0.11 2.2e-16 0.21 0.2 0.19 0.2 1.0e-15 7.0e-15 2.8e-14 3.1e-15

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.41.24.50.91.01.10.40.90.80.72.11.8-0.8-1.10.4
BMI without tail0.20.41.2-0.20.4-0.3-0.4-0.6-0.5-0.60.30.7-0.9-1.1-0.5
Body weight0.21.04.00.40.3-0.4-0.4-0.30.40.31.41.4-2.0-2.0-0.2
Epididymis fat weight2.04.77.21.61.92.02.32.22.72.42.32.31.71.92.4
Glucose2.43.67.80.41.92.82.12.61.31.61.21.62.32.31.4
Heart weight0.81.11.9-0.21.21.21.31.20.71.11.01.40.61.11.0
Left kidney weight1.02.84.61.11.51.51.71.52.22.11.92.00.91.11.9
Right kidney weight0.51.42.51.00.91.21.21.21.61.61.51.30.50.61.2
Tail length0.72.14.9-1.2-0.9-2.2-1.5-2.1-1.1-1.2-1.1-0.6-1.7-1.6-1.4
Length with tail0.20.72.70.2-0.2-1.1-0.6-0.90.50.20.50.6-1.7-1.5-0.2
Length without tail0.20.41.30.6-0.10.30.10.41.11.01.10.6-0.6-0.60.5
Liver weight, left0.20.20.9-0.30.40.50.60.60.20.3-0.20.10.70.90.4
Liver weight, right0.20.31.1-1.0-0.60.40.20.60.40.60.5-0.50.50.4-0.1
Parametrial fat weight4.79.212.22.83.03.13.13.03.53.22.63.12.62.93.4
Retroperitoneal fat weight4.214.017.91.83.63.94.24.04.14.13.03.83.74.04.0
Intraocular pressure0.40.61.5-0.2-0.2-0.7-0.7-0.9-1.2-1.1-0.9-0.5-0.8-0.7-0.8
Extensor digitorum longus weight0.93.613.6-0.3-1.3-1.9-2.0-1.8-0.8-0.80.7-0.1-3.6-3.7-1.4
Soleus weight0.82.28.0-0.20.21.81.41.71.31.40.6-0.12.82.31.1
Tibialis anterior weight3.110.827.0-2.0-2.7-3.3-3.7-3.1-2.9-2.7-1.2-1.8-5.1-5.2-3.3
Tibia length0.10.42.31.50.40.1-0.20.40.6-0.00.40.5-0.6-0.90.2
Number of licking bursts0.30.41.00.40.50.60.40.31.00.80.50.80.70.30.7
Food consumed during 24 hour testing period0.10.10.30.2-0.10.1-0.1-0.1-0.1-0.4-0.5-0.60.60.3-0.0
Times rat made contact with spout1.11.31.8-1.3-1.3-1.1-1.2-1.3-1.0-1.0-0.9-1.3-0.8-0.8-1.2
Mean time between licks in bursts1.31.83.8-1.9-1.2-1.5-1.0-1.3-1.7-0.9-0.2-0.9-2.0-1.3-1.4
Mean num. licks in bursts1.61.93.1-1.4-1.5-1.3-1.3-1.3-1.8-1.5-1.2-1.7-1.1-0.7-1.6
Std. dev. time between licks in bursts0.10.10.5-0.7-0.10.10.40.00.10.40.40.00.40.50.2
Water consumed over 24 hours0.20.20.90.0-0.5-1.0-0.4-0.90.50.1-0.1-0.2-0.1-0.30.0
Indifference point 0 sec0.10.20.7-0.6-0.8-0.4-0.3-0.10.10.30.2-0.4-0.5-0.7-0.3
Indifference point AUC0.91.04.7-0.8-2.2-0.4-1.2-0.40.20.00.0-1.6-0.8-1.3-0.7
Indifference point function ln k1.82.65.21.02.31.31.81.31.11.11.11.92.12.11.6
Indifference point function log k1.82.65.21.02.31.31.81.31.11.11.11.92.12.11.6
Delay discounting total patch changes 0 sec0.20.41.1-0.8-1.0-0.7-0.5-0.4-0.20.0-0.1-0.6-0.6-0.8-0.5
Delay discounting total patch changes 12 sec2.83.88.0-1.4-2.5-2.1-2.2-2.0-1.1-1.1-0.7-1.6-2.7-2.8-1.8
Delay discounting total patch changes 18 sec0.70.92.7-1.3-1.6-0.7-1.1-0.5-0.5-0.3-0.5-1.3-0.6-0.9-1.0
Delay discounting total patch changes 24 sec1.21.54.6-1.0-2.0-1.2-1.2-0.90.40.50.9-0.6-1.8-2.1-0.7
Delay discounting total patch changes 6 sec0.10.20.9-0.1-0.4-0.1-0.10.11.00.70.50.1-0.2-0.50.3
Delay discounting time to switch 0 sec0.40.72.41.51.40.80.60.60.10.20.51.3-0.30.10.6
Delay discounting water rate 0 sec0.30.41.2-0.8-1.1-0.4-0.1-0.10.60.4-0.1-1.01.00.50.0
Delay discounting water rate 12 sec0.30.52.7-0.60.00.10.50.30.80.60.30.11.71.20.5
Delay discounting water rate 18 sec0.50.72.2-0.20.20.10.80.21.11.10.80.41.51.30.8
Delay discounting water rate 24 sec0.30.41.80.30.70.10.50.10.40.1-0.10.51.31.00.4
Delay discounting water rate 6 sec0.20.41.9-0.9-0.2-0.30.4-0.10.40.50.20.01.40.90.2
Locomotor activity0.60.95.4-2.3-1.40.3-0.20.20.20.4-0.2-1.11.10.4-0.6
Locomotor testing distance0.50.95.4-2.3-1.30.5-0.00.50.00.40.0-1.01.10.5-0.7
Locomotor testing rearing0.40.72.3-1.5-1.40.1-0.40.1-0.2-0.1-0.3-1.41.10.5-0.7
Light reinforcement 10.10.21.3-0.2-0.80.2-0.30.3-0.3-0.2-0.4-1.10.30.2-0.3
Light reinforcement 21.92.64.22.11.01.71.51.62.01.81.41.01.51.41.9
Reaction time number correct0.60.92.6-0.10.2-1.0-1.2-0.9-1.0-1.6-1.5-0.5-0.2-0.7-0.9
Reaction time mean minus median1.01.33.00.8-0.0-0.9-1.1-0.9-1.6-1.7-1.5-0.7-1.4-1.1-1.0
Reaction time mean minus median AUC2.22.85.80.0-0.6-1.6-1.7-1.5-2.3-2.4-2.2-1.4-1.5-1.3-1.7
Reaction time num false alarms0.30.42.7-1.6-0.8-0.6-0.3-0.8-0.3-0.0-0.4-0.50.00.0-0.4
Reaction time num false alarms AUC0.71.03.6-1.9-1.0-1.2-0.7-1.3-0.8-0.4-0.8-0.7-0.6-0.5-0.8
Reaction time trials correct on left0.60.92.6-0.10.2-1.0-1.2-0.9-1.0-1.6-1.5-0.5-0.2-0.7-0.9
Reaction time trials on left0.81.13.0-0.10.1-1.1-1.3-1.0-1.1-1.7-1.6-0.6-0.2-0.8-1.0
Reaction time mean0.70.92.30.7-0.2-0.8-0.8-0.6-1.5-1.5-1.1-1.0-0.9-0.6-0.9
Reaction time mean AUC0.50.71.70.9-0.1-0.6-0.6-0.5-1.3-1.3-0.9-0.9-0.7-0.3-0.7
Median of all reaction times0.30.40.80.9-0.1-0.5-0.5-0.3-0.9-0.9-0.5-0.6-0.7-0.4-0.5
Reaction time omissions0.81.02.5-0.1-0.1-1.4-1.0-1.1-1.3-1.3-1.6-0.6-0.8-0.6-0.9
Reaction time false alarm rate0.20.32.0-1.4-0.8-0.20.3-0.30.20.80.5-0.1-0.10.20.1
Reaction time premature initiation rate0.60.81.81.20.6-0.30.5-0.11.11.01.21.4-0.8-0.50.9
Reaction time premature initiations0.40.61.70.80.2-1.3-0.7-1.10.1-0.4-0.10.6-1.2-1.2-0.1
Std. dev. reaction times1.31.84.00.2-0.4-1.3-1.2-1.2-2.0-2.0-1.9-1.2-1.1-0.8-1.3
Reaction time trials completed0.81.13.0-0.10.1-1.1-1.3-1.0-1.1-1.7-1.6-0.6-0.2-0.8-1.0
Reaction time trials AUC0.60.82.4-0.20.1-0.9-1.2-0.9-1.0-1.5-1.5-0.5-0.1-0.6-0.9
Social response proportion0.30.30.70.70.60.10.50.10.50.50.00.50.80.70.7
Social responses0.30.41.0-0.6-0.7-1.0-0.5-0.9-0.3-0.2-0.8-0.70.30.1-0.4
Social time1.52.03.2-1.3-1.0-1.6-1.4-1.5-1.8-1.6-1.8-1.3-0.8-0.8-1.6
Conditioned locomotion0.30.42.0-0.3-0.0-0.4-0.2-0.4-0.9-0.4-0.10.2-1.4-0.8-0.4
Cocaine response after cond. corrected0.20.31.4-1.2-0.20.1-0.3-0.2-0.8-0.50.0-0.2-0.0-0.2-0.6
Cocaine response after cond. not corrected0.10.20.5-0.6-0.30.4-0.20.1-0.7-0.40.1-0.50.1-0.0-0.5
Cocaine response before conditioning0.30.32.11.5-0.60.0-0.30.20.2-0.2-0.2-1.00.10.10.0
Saline control response1.31.72.9-0.8-1.2-1.3-1.6-1.5-1.2-1.2-0.9-1.0-1.4-1.7-1.4
Condit. Reinf. active minus inactive responses0.20.21.1-0.1-0.90.1-0.40.1-0.5-0.4-0.1-1.1-0.1-0.1-0.4
Condit. Reinf. active-inactive response ratio0.50.62.21.51.00.90.60.70.50.20.70.80.10.20.6
Condit. Reinf. active responses0.20.31.3-0.2-1.1-0.3-0.5-0.3-0.4-0.2-0.1-1.1-0.1-0.2-0.4
Condit. Reinf. inactive responses0.50.62.1-0.9-1.4-0.6-0.6-0.6-0.4-0.2-0.6-1.50.30.2-0.5
Condit. Reinf. lever presses0.20.21.21.1-0.50.1-0.4-0.20.60.20.4-0.3-0.1-0.50.2
Condit. Reinf. lever reinforcers received0.40.61.7-0.1-1.2-0.7-0.9-0.6-0.6-0.6-0.4-1.3-0.5-0.6-0.7
Pavlov. Cond. lever latency0.30.41.4-0.90.8-0.70.2-0.1-0.9-0.7-1.20.2-0.20.3-0.3
Pavlov. Cond. magazine entry latency2.02.35.30.6-1.8-1.4-2.0-1.8-0.8-1.2-0.1-1.5-1.9-2.3-1.2
Pavlov. Cond. change in total contacts0.50.71.91.3-1.4-0.3-1.1-0.60.2-0.30.3-1.2-0.4-1.1-0.3
Pavlov. Cond. index score0.70.92.31.5-1.1-0.3-1.3-0.90.3-0.40.6-0.8-0.9-1.5-0.3
Pavlov. Cond. latency score0.50.72.41.6-1.0-0.1-1.0-0.70.5-0.20.7-0.6-0.7-1.3-0.2
Pavlov. Cond. lever contacts0.50.72.60.3-1.6-0.2-1.2-0.8-0.1-0.40.2-1.3-0.3-1.0-0.7
Pavlov. Cond. magazine entry number2.32.98.1-1.01.61.62.22.10.71.40.11.22.32.81.3
Pavlov. Cond. intertrial magazine entries0.40.51.6-0.30.80.80.81.0-0.00.2-0.50.21.01.30.3
Pavlov. Cond. lever-magazine prob. diff.0.81.12.81.4-1.3-0.5-1.4-1.10.1-0.60.4-1.0-1.0-1.7-0.5
Pavlov. Cond. response bias0.81.12.80.5-1.7-0.7-1.4-1.2-0.2-0.60.2-1.3-1.0-1.5-0.8
Conditioned reinforcement - actives0.10.10.60.30.0-0.10.1-0.0-0.1-0.3-0.4-0.50.60.80.1
Conditioned reinforcement - inactives1.01.12.30.80.11.00.91.01.51.31.20.21.41.11.1
Conditioned locomotion1.51.83.00.70.71.21.51.21.61.61.50.71.71.71.5
Intermittent access intake day 1-15 change0.30.31.6-0.1-0.7-0.1-0.3-0.1-0.2-0.4-0.7-1.30.70.4-0.1
Intermittent access intake escalation0.30.31.8-0.1-0.9-0.2-0.4-0.2-0.3-0.4-0.6-1.30.40.2-0.3
Intermittent access intake escalation 20.50.52.2-0.1-1.2-0.5-0.8-0.5-0.2-0.5-0.6-1.5-0.1-0.4-0.5
Intermitt. access day 1 inactive lever presses2.42.63.51.21.31.81.61.81.71.61.71.41.91.51.7
Intermitt. access day 15 inactive lever presses2.72.97.51.10.21.71.31.72.72.42.50.91.61.01.8
Intermitt. access escalation Index1.81.63.3-0.30.51.51.51.41.31.81.51.00.91.11.3
Intermittent access day 1 total infusions5.05.78.21.52.02.42.42.52.82.82.92.41.92.02.6
Intermittent access day 15 total infusions2.83.15.00.90.81.81.81.92.12.01.70.72.22.22.0
Intermittent access terminal intake (last 3 days)1.61.73.31.10.31.31.21.41.81.61.70.41.31.21.5
Intermittent access total infusions2.62.84.41.10.91.91.71.92.12.02.01.11.51.61.9
Intermittent access day 1 locomotion4.04.18.31.11.41.92.12.02.52.62.92.11.41.42.2
Intermittent access day 15 total locomotion1.41.53.71.20.51.11.01.11.71.51.90.80.90.71.4
Intermittent access total locomotion5.15.710.92.01.32.52.22.53.12.93.31.91.81.62.6
Intermittent access standard deviation1.21.32.8-0.5-1.0-1.3-1.1-1.3-1.2-1.4-1.2-1.7-0.3-0.4-1.2
Cocaine induced anxiety0.30.30.6-0.0-0.5-0.3-0.7-0.3-0.5-0.7-0.3-0.7-0.8-0.8-0.7
Post-drug Anxiety0.50.61.20.3-0.4-0.6-1.0-0.5-0.8-1.1-0.6-0.7-0.9-1.0-0.9
Baseline Anxiety0.50.61.1-0.0-0.3-1.1-0.8-1.1-0.8-0.9-0.5-0.2-0.8-0.9-0.7
Lifetime Intake1.82.03.20.81.01.41.51.51.61.71.81.11.21.31.5
Incentive Sensitization - Responses0.60.61.10.80.40.90.60.91.10.80.80.40.40.50.9
Incentive Sensitization - Breakpoint1.01.01.91.00.61.20.91.21.41.11.10.70.70.71.2
Progressive ratio test 1 active lever presses0.70.81.60.30.50.81.00.81.01.00.70.41.21.21.0
Progressive ratio test 1 breakpoint0.50.51.40.30.50.60.90.60.70.70.40.31.11.20.8
Progressive ratio test 1 inactive lever presses0.40.41.80.2-0.00.40.40.41.11.01.40.60.3-0.00.5
Progressive ratio test 2 active lever presses1.61.72.51.00.91.41.41.41.51.31.20.71.41.61.5
Progressive ratio test 2 breakpoint1.82.03.30.80.91.51.51.61.71.41.10.61.71.81.6
Progressive ratio test 2 inactive lever presses2.02.35.01.10.41.41.31.52.22.02.00.71.71.31.7
Total sessions with >9 infusions1.71.82.70.71.51.31.61.31.11.31.51.61.11.41.4
Short access day 1 total inactive lever presses1.51.72.10.51.11.31.51.31.31.41.31.41.31.41.4
Short access day 10 total inactive lever presses0.60.71.6-0.60.70.91.00.90.30.70.50.81.31.20.5
Short access day 1 total infusions0.50.50.90.20.90.50.90.60.50.70.71.00.60.90.8
Short access day 10 total infusions3.63.96.61.31.82.02.12.12.12.32.62.21.31.52.1
Short access total infusions1.11.32.30.51.21.01.31.11.11.31.51.40.70.91.2
Short access day 1 locomotion0.40.41.80.40.30.10.60.20.91.01.30.70.10.10.6
Short access day 10 total locomotion1.71.84.71.11.01.21.31.21.61.62.21.50.70.71.4
Short access total locomotion1.41.45.10.90.70.81.10.91.51.62.31.30.30.41.2
Compulsive drug intake3.53.44.8-1.9-1.5-2.0-1.8-2.1-2.2-1.9-1.6-1.4-1.7-1.8-2.2
One hour access (0.3 mA shock)2.63.05.00.50.71.81.81.92.12.11.70.72.22.11.8
One hour access (shock baseline)3.44.06.41.41.22.22.12.32.32.01.40.82.52.52.3
Number of responses in last shaping day0.30.40.7-0.8-0.6-0.8-0.4-0.8-0.7-0.4-0.2-0.5-0.5-0.5-0.6
Context. condit. distance diff. score0.10.10.30.30.4-0.00.3-0.10.50.40.50.60.10.20.4
Locomotion velocity, session 10.80.82.0-1.2-0.9-0.5-0.8-0.5-1.4-1.1-0.5-1.0-0.8-0.6-1.2
Locomotion distance, session 10.91.13.1-1.8-1.7-0.6-1.0-0.6-0.7-0.30.3-1.2-1.0-1.0-1.2
Locomotion velocity, session 20.60.72.5-0.5-1.1-0.7-0.7-0.6-0.3-0.10.6-0.5-1.6-1.4-0.7
Locomotion distance, session 21.01.45.0-2.2-1.8-0.8-1.1-0.7-0.8-0.40.1-1.1-1.3-1.2-1.4
Locomotion velocity, session 31.41.64.80.80.71.11.21.01.81.72.21.50.40.41.2
Locomotion distance, session 30.30.30.60.50.80.10.70.40.60.60.40.80.50.60.7
Stereotopy head waving bouts, day 30.80.92.6-0.50.21.31.01.20.91.41.60.80.40.50.5
Stereotopy head waving duration, day 30.40.51.3-0.20.60.80.80.60.60.91.21.00.10.20.5
Locomotion velocity, session 70.80.81.60.50.90.81.11.21.01.20.91.20.40.61.0
Locomotion distance, session 70.40.51.2-0.10.80.40.90.70.40.90.81.10.30.60.6
Stereotopy head waving bouts, day 70.10.10.50.70.50.20.10.3-0.1-0.10.10.4-0.6-0.20.1
Stereotopy head waving duration, day 70.20.31.50.60.1-0.4-0.4-0.2-0.2-0.3-0.00.3-1.2-0.9-0.2
Locomotion velocity, session 80.30.30.9-0.50.4-0.8-0.3-0.5-0.7-0.7-0.90.2-0.2-0.2-0.5
Locomotion distance, session 80.20.31.0-0.6-0.10.40.40.50.60.81.00.4-0.10.10.2
Degree of sensitization distance0.40.41.4-0.30.11.00.50.90.30.71.20.5-0.0-0.00.1
Degree of sensitization stereotypy0.40.41.41.20.3-0.4-0.5-0.3-0.4-0.7-0.40.1-1.2-0.8-0.2
Condit. Reinf. active minus inactive responses1.51.73.5-1.0-1.8-0.6-1.5-0.9-1.3-1.2-0.4-1.9-1.4-1.4-1.5
Condit. Reinf. active-inactive response ratio3.33.55.8-1.6-2.1-1.2-2.0-1.5-2.3-2.1-1.3-2.4-1.7-1.7-2.2
Condit. Reinf. active responses0.70.83.2-0.6-1.8-0.0-0.9-0.2-0.3-0.20.6-1.5-0.9-1.0-0.9
Condit. Reinf. inactive responses1.01.12.90.7-0.11.10.81.11.71.51.70.40.90.50.9
Incentive salience index mean0.50.62.5-0.6-1.60.0-0.7-0.1-0.2-0.10.5-1.3-0.8-0.8-0.7
Condit. Reinf. lever presses0.50.71.80.6-0.20.80.71.01.21.31.40.20.40.40.8
Time in familiar zone, hab. session 10.30.31.1-0.3-1.00.0-0.2-0.00.90.80.6-0.70.50.10.0
Time in novel zone, hab. session 10.30.30.90.21.00.30.30.1-0.6-0.7-0.80.40.60.70.1
Total zone transitions, hab. session 10.60.81.6-1.3-1.0-0.7-0.9-0.8-1.0-0.8-0.6-0.9-1.0-0.9-1.0
Total locomotion distance, hab. session 10.10.10.6-0.2-0.10.70.20.50.30.30.80.10.0-0.00.1
Locomotion velocity, hab. session 10.10.20.4-0.7-0.70.1-0.30.0-0.2-0.10.4-0.3-0.7-0.7-0.5
Time in familiar zone, hab. session 20.20.21.00.10.2-0.2-0.2-0.1-0.6-0.6-1.0-0.40.60.5-0.3
Time in novel zone, hab. session 20.20.20.6-0.6-0.70.0-0.1-0.10.40.30.8-0.1-0.5-0.5-0.1
Total zone transitions, hab. session 21.01.34.0-1.8-2.0-0.8-1.0-0.6-0.7-0.30.0-1.5-0.9-0.9-1.2
Total locomotion distance, hab. session 20.40.51.9-1.2-1.4-0.1-0.4-0.1-0.10.20.7-1.0-0.3-0.3-0.6
Locomotion velocity, hab. session 20.20.31.2-0.9-1.10.3-0.10.30.20.50.9-0.7-0.1-0.1-0.3
Novel to familiar place preference ratio0.30.31.00.30.4-0.30.1-0.20.20.20.50.9-1.0-0.90.2
Novelty place preference0.30.31.20.50.6-0.20.3-0.10.40.30.61.1-0.7-0.60.4
Time in novel zone, NPP test0.30.31.00.30.5-0.30.0-0.30.20.10.51.0-0.9-0.80.1
Total zone transitions, NPP test1.62.24.1-2.0-2.0-1.2-1.5-1.0-1.4-1.0-0.6-1.6-1.7-1.5-1.7
Total locomotion distance, NPP test0.40.62.5-1.6-1.4-0.1-0.4-0.1-0.30.10.3-0.9-0.5-0.4-0.7
Locomotion velocity, NPP test0.30.52.3-1.5-1.3-0.1-0.30.0-0.30.20.1-0.9-0.5-0.2-0.6
Pavlov. Cond. lever latency0.20.20.6-0.10.8-0.2-0.1-0.5-0.5-0.7-0.80.50.10.1-0.2
Pavlov. Cond. magazine entry latency0.20.21.51.2-0.00.20.10.50.50.40.6-0.1-0.4-0.30.3
Pavlov. Cond. change in total contacts0.20.20.70.4-0.80.2-0.10.30.20.30.4-0.8-0.2-0.20.0
Pavlov. Cond. index score0.10.10.40.6-0.5-0.1-0.20.30.20.10.1-0.7-0.3-0.30.0
Pavlov. Cond. latency score0.10.10.30.6-0.40.10.10.50.40.30.3-0.50.10.00.2
Pavlov. Cond. lever contacts0.20.20.50.3-0.30.40.40.70.60.70.6-0.30.30.40.4
Pavlov. Cond. magazine entry number0.30.40.9-1.00.20.60.50.20.40.70.50.60.90.70.3
Pavlov. Cond. intertrial magazine entries1.01.24.7-1.7-2.2-0.2-1.0-0.4-0.3-0.3-0.5-1.9-0.2-0.6-1.0
Pavlov. Cond. lever-magazine prob. diff.0.10.20.70.4-0.8-0.2-0.30.10.10.00.1-0.8-0.5-0.5-0.1
Pavlov. Cond. response bias0.10.20.50.7-0.6-0.1-0.20.10.10.00.2-0.6-0.7-0.40.0
Bone: apparent density0.40.61.30.80.40.90.70.81.11.01.00.50.50.50.9
Bone surface0.50.93.21.81.11.00.70.90.80.70.81.1-0.20.11.0
Bone volume0.71.23.31.80.91.20.91.11.41.11.00.90.60.61.3
Bone: connectivity density0.10.20.60.70.20.40.30.40.40.40.80.5-0.5-0.30.4
Bone: cortical apparent density0.70.91.7-0.5-1.3-1.2-1.0-1.0-0.5-0.7-0.6-1.2-0.9-1.1-0.8
Bone: cortical area0.20.20.90.3-0.80.2-0.10.10.90.70.5-0.50.2-0.00.3
Bone: cortical porosity0.50.51.1-0.40.1-0.9-0.6-0.8-1.0-0.9-1.1-0.2-0.6-0.5-0.6
Bone: cortical porosity1.01.12.2-0.8-0.1-1.2-0.9-1.1-1.5-1.3-1.3-0.3-1.1-0.8-0.9
Bone: cortical thickness2.33.87.3-1.8-2.7-2.3-2.2-2.2-1.2-1.3-1.3-2.3-1.7-2.0-1.7
Bone: cortical thickness0.60.71.5-0.4-0.8-1.2-0.7-1.2-0.7-0.8-0.7-0.8-0.8-0.7-0.5
Bone: cortical tissue density0.81.01.7-0.5-1.3-1.3-1.1-1.2-0.7-0.8-0.7-1.2-1.1-1.2-0.9
Bone: elastic displacement1.01.22.5-1.6-0.8-1.1-0.7-0.8-1.4-1.3-1.3-1.2-0.3-0.2-1.1
Bone: elastic work1.62.13.1-1.8-1.5-1.7-1.5-1.6-1.3-1.3-1.2-1.4-1.1-1.3-1.4
Bone: endosteal estimation3.98.311.02.52.63.33.02.93.23.12.82.72.72.83.0
Bone: endosteal perimeter5.511.314.83.63.43.83.53.43.43.22.93.23.13.23.5
Bone: final force0.20.30.90.1-1.0-0.2-0.6-0.30.30.20.5-0.6-0.6-0.8-0.2
Bone: final moment0.20.31.0-0.0-1.0-0.1-0.5-0.20.30.20.5-0.6-0.6-0.8-0.2
Bone: marrow area4.18.711.32.52.73.43.13.03.33.22.82.82.82.93.0
Bone: maximum diameter0.81.43.11.60.71.21.00.91.81.51.30.90.80.71.3
Bone: maximum force0.50.92.31.30.10.80.40.71.41.21.50.7-0.2-0.30.9
Bone: maximum moment0.40.72.11.2-0.00.80.40.71.31.11.40.5-0.2-0.30.8
Bone: minimum diameter3.36.210.91.51.02.92.42.63.33.32.91.62.42.42.4
Bone: periosteal estimation2.04.07.71.91.22.21.91.92.82.52.21.51.81.62.2
Bone: periosteal perimeter0.81.32.31.30.61.50.91.21.51.21.10.51.21.01.1
Bone: post-yield work6.28.411.13.32.63.32.93.13.23.02.82.72.22.33.0
Bone: stiffness0.40.62.21.50.20.70.40.51.30.90.90.40.20.20.9
Bone: tissue strength0.20.20.6-0.1-0.10.40.40.60.30.40.2-0.10.80.60.3
Bone: trabecular number0.30.51.30.90.40.70.60.61.00.91.10.7-0.00.10.8
Bone: trabecular spacing1.52.03.5-1.7-1.5-1.3-1.4-1.2-1.5-1.5-1.4-1.9-0.3-0.7-1.6
Bone: trabecular thickness1.11.33.01.00.61.30.91.11.71.20.70.61.51.21.3
Bone: trabecular tissue density0.60.83.4-0.10.50.70.80.70.80.6-0.20.11.81.60.7
Breakpoint value in progressive ratio session3.13.55.0-0.4-1.5-2.1-2.1-2.1-1.9-2.0-1.6-1.6-2.1-2.2-1.9
Distance traveled before self-admin0.40.51.40.8-0.3-0.4-0.9-0.4-0.4-0.8-0.5-0.3-0.9-1.2-0.5
Distance traveled after self-admin0.00.00.10.4-0.30.1-0.30.10.1-0.1-0.1-0.3-0.1-0.3-0.0
Delta time in closed arm before/after self-admin1.71.74.5-2.1-1.5-1.4-1.3-1.4-0.7-0.40.1-0.5-1.2-1.8-1.4
Delta time in open arm before/after self-admin0.90.82.20.3-1.3-0.6-1.0-0.6-0.7-0.7-0.2-1.2-1.5-1.3-0.8
Diff in mean of infusions in LGA sessions2.93.34.7-0.7-1.6-2.1-2.0-2.2-1.8-1.8-1.5-1.6-2.0-2.1-1.9
Extinction: sum of active levers before priming1.01.03.20.2-0.4-1.2-1.0-1.1-1.0-0.8-0.4-0.2-1.8-1.6-1.0
Active lever presses in extinction session 61.81.83.00.3-1.1-1.5-1.5-1.4-1.1-1.4-1.2-1.3-1.7-1.7-1.2
Delta distance traveled before/after self-admin0.10.10.4-0.70.20.10.50.2-0.20.20.10.10.40.60.1
Delta ambulatory time before/after self-admin0.10.10.4-0.60.2-0.10.3-0.0-0.5-0.2-0.3-0.10.40.5-0.1
Time in closed arm before self-admin0.50.62.51.60.90.80.60.80.70.30.20.50.50.60.9
Time in closed arm after self-admin0.20.20.7-0.40.10.30.20.30.70.40.20.20.90.40.4
Time in open arm before self-admin0.40.53.8-1.9-0.1-0.40.2-0.4-0.40.1-0.30.20.60.7-0.3
Time in open arm after self-admin1.01.11.7-1.2-1.1-1.1-0.9-1.1-1.3-1.0-1.1-1.1-0.9-0.7-1.2
Sum of active levers in priming session hrs 5-61.41.41.90.2-1.1-1.4-1.2-1.3-1.2-1.2-1.0-1.3-1.4-1.2-1.1
Time to tail flick, vehicle, before self-admin0.80.81.81.21.10.80.80.70.80.81.11.3-0.00.11.0
Time to tail flick, vehicle, after self-admin0.10.10.60.10.7-0.2-0.1-0.2-0.2-0.20.20.8-0.5-0.5-0.0
Time to tail flick, test, before self-admin1.21.12.20.21.01.21.01.11.41.21.21.50.80.51.2
Time to tail flick, test, after self-admin0.00.00.1-0.20.00.30.10.30.1-0.0-0.4-0.10.20.30.1
Delta time to tail flick, vehicle, before/after SA0.20.20.4-0.7-0.4-0.5-0.5-0.5-0.4-0.5-0.5-0.5-0.2-0.3-0.5
Delta time to tail flick, test, before/after SA2.22.03.9-0.8-1.8-1.4-1.4-1.4-1.5-1.3-1.3-2.0-1.2-0.9-1.6
Ambulatory time before self-admin0.50.51.10.9-0.5-0.4-1.0-0.4-0.3-0.8-0.5-0.6-0.9-1.0-0.5
Ambulatory time after self-admin0.40.51.31.10.20.80.40.81.00.70.80.30.60.30.8
Total heroin consumption4.55.48.1-0.8-1.4-2.8-2.4-2.8-2.6-2.5-2.1-1.4-2.8-2.8-2.4
Area under the delay curve0.90.92.20.31.21.01.21.00.71.10.91.50.30.70.9
Delay disc. indifference point, 0s delay1.51.63.40.21.51.51.31.51.11.31.41.90.90.81.1
Delay disc. indifference point, 16s delay0.40.40.70.50.40.70.60.70.60.80.80.6-0.00.30.6
Delay disc. indifference point, 2s delay2.02.23.41.01.71.71.71.81.21.51.21.71.11.41.4
Delay disc. indifference point, 24s delay0.20.20.5-0.4-0.00.40.50.40.30.70.60.40.00.40.3
Delay disc. indifference point, 4s delay1.01.13.2-0.11.20.81.20.91.01.31.11.80.40.70.9
Delay disc. indifference point, 8s delay0.80.82.7-0.21.50.81.20.60.20.80.41.70.30.80.7
Delay discount exponential model param0.91.02.3-0.4-1.2-1.1-1.3-1.0-0.7-1.1-1.0-1.5-0.3-0.8-0.9
Delay discount hyperbolic model param1.11.22.6-0.4-1.3-1.2-1.3-1.1-0.7-1.2-1.0-1.6-0.4-0.8-1.0
Fecal boli incidents, locomotor time 10.30.31.31.0-0.50.3-0.70.20.0-0.6-0.3-1.20.1-0.3-0.1
Change in fecal boli incidents, locomotor task1.71.64.5-0.41.81.01.60.80.71.10.92.11.31.51.0
Time >=10cm from walls, locomotor time 12.22.24.32.11.51.71.51.61.31.21.21.31.31.51.5
Bouts of movement, locomotor time 14.55.09.2-1.0-2.8-2.3-2.8-2.2-1.6-2.1-2.0-3.0-1.7-2.4-2.2
Total resting periods, locomotor time 12.73.06.3-0.5-2.3-1.7-2.2-1.5-1.1-1.6-1.6-2.5-1.3-1.9-1.6
Rest time, locomotor task time 10.10.10.3-0.10.10.30.20.50.50.3-0.1-0.20.60.40.5
Distance moved, locomotor task time 10.30.31.30.71.00.00.5-0.1-0.2-0.00.31.1-0.30.30.2
Vertical activity count, locomotor time 10.50.51.40.21.20.51.10.4-0.10.30.11.10.51.20.4
Time >=10cm from walls, locomotor time 20.10.11.01.00.30.20.00.1-0.2-0.4-0.5-0.20.00.30.2
Bouts of movement, locomotor time 24.34.67.4-1.3-2.6-2.1-2.6-2.1-1.8-1.9-0.8-2.3-2.3-2.7-2.4
Total resting periods, locomotor time 23.84.17.0-1.4-2.6-1.9-2.4-1.9-1.6-1.7-0.6-2.3-2.0-2.5-2.3
Rest time, locomotor task time 20.20.20.6-0.60.10.40.40.50.50.50.40.10.70.80.4
Distance moved, locomotor task time 20.30.41.10.70.5-0.5-0.2-0.5-0.9-1.0-1.10.2-0.5-0.3-0.1
Vertical activity count, locomotor time 20.60.72.3-0.80.4-0.7-0.2-0.7-1.5-1.2-1.50.0-0.30.0-0.8
Weight adjusted by age1.71.84.60.2-0.6-1.0-1.5-1.3-1.6-1.6-0.4-0.5-2.0-2.1-1.5
Seeking ratio, delayed vs. immediate footshock0.40.41.4-0.2-0.40.50.50.41.11.21.20.20.40.20.6
Locomotion in novel chamber2.53.14.71.81.72.11.72.21.81.40.81.32.12.01.8
Locomotion in novel chamber post-restriction0.20.20.6-0.50.5-0.10.2-0.1-0.6-0.5-0.80.00.20.6-0.2
Progressive ratio0.30.40.80.90.70.40.70.60.30.50.70.8-0.30.30.6
Food seeking constrained by brief footshock0.10.20.9-1.0-0.4-0.2-0.1-0.3-0.7-0.3-0.1-0.3-0.30.1-0.4
Seeking ratio, punishment vs. effort0.40.52.9-1.7-1.0-0.4-0.6-0.7-0.5-0.3-0.3-0.80.0-0.2-0.8
Run reversals in cocaine runway, females0.80.81.80.30.80.70.90.90.91.11.21.40.30.40.8
Run reversals in cocaine runway, males0.50.41.1-0.40.00.90.91.00.30.70.00.00.81.00.6
Latency to leave start box in cocaine runway3.53.85.21.72.02.02.12.12.22.11.72.11.51.72.3
Latency to leave start box in cocaine runway, F0.90.91.90.80.61.00.91.11.41.21.10.80.60.61.2
Latency to leave start box in cocaine runway, M3.33.26.01.72.41.72.01.71.21.20.51.91.92.22.0
Cd content in liver0.20.30.7-0.10.40.70.30.5-0.6-0.4-0.6-0.40.70.8-0.1
Co content in liver0.80.92.4-1.1-0.6-0.8-0.6-1.0-1.2-1.2-1.6-1.20.30.3-0.8
Cu content in liver0.20.21.1-0.70.0-0.8-0.2-1.1-0.2-0.2-0.10.2-0.5-0.4-0.2
Fe content in liver0.00.00.10.10.3-0.2-0.1-0.4-0.0-0.20.10.3-0.2-0.2-0.0
K content in liver0.90.92.70.50.00.80.80.91.41.61.60.60.10.20.8
Mg content in liver0.80.82.4-0.3-0.51.00.61.01.31.51.60.10.50.30.5
Mn content in liver0.20.20.80.2-0.2-0.40.0-0.00.30.70.60.3-0.9-0.70.1
Na content in liver0.20.20.6-0.2-0.70.1-0.4-0.0-0.4-0.2-0.0-0.8-0.5-0.4-0.5
Rb content in liver0.91.12.8-0.10.41.11.01.01.41.30.90.41.71.40.9
Se content in liver0.30.40.80.90.40.10.40.10.70.80.90.8-0.5-0.30.5
Sr content in liver4.44.08.0-1.8-1.9-1.9-2.2-1.9-1.9-1.7-0.9-1.4-2.8-2.8-2.1
Zn content in liver2.52.86.7-1.3-2.6-1.4-1.7-1.2-0.9-0.90.0-2.0-2.2-2.4-1.6