Cpeb3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability ENSRNOG00000020689 0.06 0.04 4.7e-07 0.04 0.06 0.05 0.05 1.1e-05 3.1e-07 2.5e-06 2.1e-06
2 BLA gene expression ENSRNOG00000020689 0.17 0.12 4.1e-05 0.03 0.07 0.06 0.05 8.6e-03 1.7e-04 3.6e-04 1.4e-03
3 Brain alternative TSS ENSRNOT00000047387 0.04 0.03 5.4e-04 0.04 0.04 0.04 0.04 8.9e-05 1.1e-04 1.9e-04 1.1e-04
4 Brain alternative TSS ENSRNOT00000114370 0.04 0.03 6.9e-04 0.04 0.04 0.04 0.04 1.2e-04 1.7e-04 3.1e-04 1.8e-04
5 Brain mRNA stability ENSRNOG00000020689 0.23 0.12 6.5e-15 0.15 0.16 0.17 0.16 7.0e-14 1.2e-14 3.3e-15 6.7e-15
6 Eye gene expression ENSRNOG00000020689 0.37 0.2 6.2e-03 0.21 0.08 0.04 0.12 4.1e-04 2.2e-02 7.7e-02 8.0e-03
7 Eye mRNA stability ENSRNOG00000020689 0.35 0.2 5.3e-03 0.3 0.13 0.23 0.29 1.5e-05 5.1e-03 1.7e-04 2.5e-05
8 Liver intron excision ratio chr1:234774205:234783376 0.05 0.04 3.3e-04 0.03 0.03 0.03 0.02 4.4e-04 3.8e-04 2.6e-04 8.8e-04
9 Liver intron excision ratio chr1:234783490:234795956 0.05 0.04 1.6e-04 0.03 0.03 0.03 0.03 2.8e-04 2.3e-04 6.5e-04 3.7e-04
10 Liver mRNA stability ENSRNOG00000020689 0.06 0.05 4.6e-04 0.01 0.02 0.02 0.02 1.3e-02 1.0e-03 5.8e-03 4.5e-03
11 NAcc mRNA stability ENSRNOG00000020689 0.06 0.04 2.9e-04 0.03 0.04 0.04 0.03 3.2e-03 5.7e-04 5.3e-04 1.4e-03
12 PL gene expression ENSRNOG00000020689 0.04 0.03 8.0e-03 0.03 0.01 0.02 0.01 3.6e-03 2.8e-02 1.5e-02 2.3e-02
13 PL mRNA stability ENSRNOG00000020689 0.04 0.03 2.8e-03 0 0.01 0.01 0 1.2e-01 4.0e-02 5.6e-02 2.0e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail0.10.31.8-0.6-0.10.4-0.40.9-0.4-0.41.3-0.5-0.40.2-0.1-0.5
BMI without tail0.10.31.7-0.4-0.50.2-0.20.0-0.3-0.31.3-0.4-0.60.3-0.4-0.5
Body weight1.14.810.7-2.11.22.4-2.42.4-2.3-2.33.3-2.1-1.2-2.12.1-1.5
Epididymis fat weight0.20.51.6-0.11.20.5-0.51.3-0.4-0.40.6-0.00.5-0.61.10.4
Glucose0.30.52.1-0.40.00.6-0.60.3-0.6-0.61.4-0.6-0.6-0.90.7-0.5
Heart weight0.81.13.6-0.5-1.90.1-0.1-1.1-0.1-0.11.4-0.9-1.70.3-1.3-1.4
Left kidney weight0.72.06.3-1.00.71.5-1.51.2-1.4-1.42.5-1.3-0.9-1.81.5-0.9
Right kidney weight0.30.82.8-0.30.20.8-0.80.6-0.8-0.81.7-0.9-0.7-1.50.9-0.5
Tail length0.61.73.6-0.91.11.4-1.41.0-1.4-1.41.8-1.1-0.4-1.81.9-0.5
Length with tail1.45.28.8-1.91.72.5-2.52.1-2.5-2.52.9-2.1-1.0-3.02.8-1.2
Length without tail1.83.98.3-1.42.32.1-2.12.7-2.0-2.01.6-1.3-0.0-2.62.9-0.4
Liver weight, left2.94.77.4-1.82.02.4-2.42.5-2.4-2.42.7-1.7-0.5-2.62.7-0.9
Liver weight, right0.91.64.3-0.51.91.1-1.11.7-1.1-1.11.0-0.40.6-1.62.10.3
Parametrial fat weight0.40.82.2-0.60.70.9-0.90.9-0.9-0.91.5-0.8-0.4-1.21.0-0.4
Retroperitoneal fat weight0.10.40.7-0.60.40.7-0.70.8-0.7-0.70.8-0.6-0.3-0.70.6-0.4
Intraocular pressure0.30.51.0-0.9-0.40.7-0.7-0.3-0.7-0.70.3-0.9-1.0-0.4-0.1-1.0
Extensor digitorum longus weight0.62.47.9-0.32.61.3-1.32.2-1.1-1.10.9-0.11.1-1.82.80.8
Soleus weight0.92.54.8-2.1-0.61.6-1.60.2-1.7-1.71.2-2.1-2.1-1.20.6-2.2
Tibialis anterior weight0.93.211.8-0.03.40.9-0.92.8-0.9-0.9-0.30.42.0-1.73.21.4
Tibia length0.20.51.1-0.7-0.50.8-0.8-0.2-0.8-0.80.9-1.0-1.0-0.50.0-0.9
Number of licking bursts2.63.14.72.10.1-2.12.1-0.52.12.1-1.32.21.91.8-1.12.0
Food consumed during 24 hour testing period0.10.10.30.1-0.40.0-0.0-0.4-0.2-0.20.1-0.2-0.30.1-0.5-0.2
Times rat made contact with spout0.60.72.10.71.1-0.50.50.80.40.4-1.01.01.40.7-0.21.2
Mean time between licks in bursts0.81.13.10.7-1.8-0.90.9-1.71.11.10.50.3-0.61.0-1.5-0.2
Mean num. licks in bursts1.31.62.8-1.50.51.6-1.60.9-1.7-1.70.6-1.4-0.9-1.20.9-1.1
Std. dev. time between licks in bursts1.61.93.51.4-1.6-1.61.6-1.91.71.7-0.41.10.11.6-1.70.5
Water consumed over 24 hours1.21.44.21.31.6-0.80.80.80.80.8-0.91.52.10.50.31.9
Indifference point 0 sec0.20.31.0-0.3-1.00.1-0.1-0.8-0.3-0.30.1-0.6-1.0-0.0-0.5-0.8
Indifference point AUC0.60.71.51.20.0-1.01.0-0.51.01.0-0.21.00.90.4-0.41.0
Indifference point function ln k1.21.72.7-1.60.31.6-1.60.9-1.7-1.70.7-1.5-1.2-1.21.0-1.4
Indifference point function log k1.21.72.7-1.60.31.6-1.60.9-1.7-1.70.7-1.5-1.2-1.21.0-1.4
Delay discounting total patch changes 0 sec0.20.41.3-0.4-1.00.2-0.2-0.8-0.4-0.40.2-0.7-1.1-0.1-0.4-0.9
Delay discounting total patch changes 12 sec1.11.42.11.3-0.9-1.51.5-1.31.41.4-0.61.10.51.3-1.40.8
Delay discounting total patch changes 18 sec0.20.30.60.6-0.4-0.60.6-0.60.60.6-0.60.50.30.7-0.80.4
Delay discounting total patch changes 24 sec0.10.10.40.40.0-0.10.1-0.60.20.2-0.10.20.1-0.20.40.3
Delay discounting total patch changes 6 sec0.50.82.20.8-1.4-1.01.0-1.50.90.9-0.10.3-0.40.6-1.3-0.1
Delay discounting time to switch 0 sec1.01.52.01.3-0.2-1.41.4-0.61.41.4-1.41.41.11.3-0.91.2
Delay discounting water rate 0 sec0.30.50.8-0.70.20.9-0.90.4-0.8-0.80.1-0.8-0.6-0.80.6-0.6
Delay discounting water rate 12 sec0.81.23.2-1.1-0.11.3-1.30.5-1.3-1.31.8-1.2-1.1-0.60.4-1.1
Delay discounting water rate 18 sec1.11.42.3-1.20.61.4-1.40.8-1.5-1.51.2-1.2-0.7-1.01.3-0.9
Delay discounting water rate 24 sec1.52.03.7-1.11.31.5-1.51.8-1.5-1.51.9-1.1-0.3-1.51.8-0.6
Delay discounting water rate 6 sec0.20.30.9-0.6-0.70.6-0.6-0.3-0.4-0.40.3-0.7-0.9-0.1-0.1-0.9
Locomotor activity0.40.71.10.8-0.6-0.90.9-1.01.01.0-1.00.80.41.0-1.00.5
Locomotor testing distance0.61.01.80.9-0.9-1.11.1-1.31.11.1-1.10.80.21.1-1.20.4
Locomotor testing rearing0.10.20.6-0.00.80.0-0.00.5-0.1-0.1-0.20.10.5-0.50.70.4
Light reinforcement 10.10.10.5-0.7-0.30.3-0.30.0-0.3-0.3-0.0-0.4-0.50.1-0.1-0.6
Light reinforcement 22.63.56.01.6-1.3-2.32.3-1.52.32.3-1.31.91.02.5-2.11.2
Reaction time number correct0.71.02.0-1.11.01.0-1.01.4-1.0-1.00.2-0.8-0.2-1.21.4-0.5
Reaction time mean minus median0.81.13.2-1.0-1.40.7-0.7-0.5-0.7-0.70.9-1.3-1.8-0.2-0.5-1.6
Reaction time mean minus median AUC0.60.72.7-0.5-1.60.0-0.0-1.00.00.00.4-0.7-1.40.4-1.2-1.2
Reaction time num false alarms0.70.93.2-0.31.70.6-0.61.2-0.8-0.80.3-0.10.7-1.31.80.4
Reaction time num false alarms AUC0.40.62.3-0.11.40.5-0.50.9-0.6-0.60.3-0.10.6-1.11.50.4
Reaction time trials correct on left0.71.02.0-1.11.01.0-1.01.4-1.0-1.00.2-0.8-0.2-1.21.4-0.5
Reaction time trials on left0.71.02.1-1.11.01.0-1.01.4-1.0-1.00.2-0.8-0.2-1.21.4-0.5
Reaction time mean1.11.53.51.1-1.7-1.21.2-1.91.21.2-0.60.7-0.21.5-1.70.2
Reaction time mean AUC1.41.94.21.3-1.9-1.41.4-2.11.41.4-0.80.9-0.11.6-1.90.3
Median of all reaction times1.82.44.61.6-1.7-1.61.6-2.11.71.7-1.21.30.31.9-1.90.7
Reaction time omissions0.10.10.3-0.0-0.50.2-0.2-0.5-0.2-0.20.3-0.3-0.5-0.20.1-0.4
Reaction time false alarm rate0.20.20.80.20.90.2-0.20.3-0.3-0.30.30.10.5-0.60.90.5
Reaction time premature initiation rate1.11.53.1-1.20.81.4-1.41.2-1.4-1.41.8-1.1-0.6-0.91.4-0.8
Reaction time premature initiations2.53.65.3-2.01.32.2-2.22.0-2.1-2.12.1-1.8-0.9-1.82.3-1.3
Std. dev. reaction times0.71.04.1-0.2-2.0-0.00.0-1.40.10.10.8-0.7-1.60.6-1.4-1.2
Reaction time trials completed0.71.02.1-1.11.01.0-1.01.4-1.0-1.00.2-0.8-0.2-1.21.4-0.5
Reaction time trials AUC0.50.71.8-0.81.10.7-0.71.4-0.7-0.70.0-0.40.2-1.01.3-0.1
Social response proportion0.10.10.1-0.4-0.4-0.30.30.20.20.20.1-0.1-0.30.1-0.2-0.3
Social responses0.81.13.0-1.5-0.90.7-0.7-0.2-0.7-0.70.5-1.4-1.7-0.80.1-1.7
Social time0.50.71.20.9-0.3-1.11.1-0.71.01.0-0.90.80.50.5-0.50.7
Conditioned locomotion0.40.51.1-0.70.90.7-0.71.0-0.8-0.80.7-0.50.0-0.80.9-0.2
Cocaine response after cond. corrected0.00.00.1-0.2-0.30.0-0.0-0.2-0.1-0.10.2-0.2-0.30.2-0.3-0.3
Cocaine response after cond. not corrected0.10.10.4-0.20.50.4-0.40.5-0.4-0.40.3-0.20.1-0.50.60.0
Cocaine response before conditioning0.20.30.80.50.9-0.00.00.50.00.00.10.40.8-0.50.80.7
Saline control response0.60.72.20.81.3-0.50.50.90.40.4-0.61.01.50.30.51.3
Condit. Reinf. active minus inactive responses0.70.93.0-0.01.70.6-0.61.2-0.6-0.60.40.10.8-1.31.70.6
Condit. Reinf. active-inactive response ratio0.30.30.90.41.0-0.10.10.40.10.1-0.20.50.8-0.50.90.7
Condit. Reinf. active responses1.62.23.9-1.21.41.6-1.61.4-1.7-1.71.4-1.2-0.4-2.02.0-0.6
Condit. Reinf. inactive responses1.72.13.4-1.50.31.7-1.70.9-1.7-1.71.8-1.7-1.3-1.41.0-1.4
Condit. Reinf. lever presses0.10.10.5-0.3-0.00.3-0.30.1-0.3-0.30.7-0.4-0.3-0.30.0-0.3
Condit. Reinf. lever reinforcers received0.91.32.6-0.81.31.2-1.21.2-1.2-1.21.1-0.8-0.1-1.61.6-0.3
Pavlov. Cond. lever latency0.20.31.10.11.10.2-0.20.8-0.2-0.2-0.30.30.7-0.31.00.6
Pavlov. Cond. magazine entry latency0.50.61.21.10.1-0.90.9-0.10.80.8-0.21.00.90.6-0.41.0
Pavlov. Cond. change in total contacts0.20.20.60.60.5-0.30.30.30.30.3-0.50.60.70.1-0.10.8
Pavlov. Cond. index score0.00.00.10.30.1-0.20.20.10.10.10.20.20.2-0.0-0.10.3
Pavlov. Cond. latency score0.00.00.00.10.20.0-0.00.2-0.0-0.00.20.00.1-0.20.10.1
Pavlov. Cond. lever contacts0.10.10.4-0.1-0.60.0-0.0-0.40.00.00.4-0.3-0.5-0.0-0.5-0.4
Pavlov. Cond. magazine entry number1.11.32.7-1.6-0.11.3-1.30.4-1.3-1.30.6-1.5-1.3-0.90.7-1.5
Pavlov. Cond. intertrial magazine entries0.81.02.5-0.61.51.0-1.01.4-0.9-0.90.4-0.40.4-1.01.60.1
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.50.3-0.30.30.20.30.30.20.40.50.0-0.00.5
Pavlov. Cond. response bias0.30.40.70.9-0.3-0.70.7-0.40.70.7-0.30.70.40.5-0.70.6
Conditioned reinforcement - actives2.32.23.5-1.90.41.8-1.80.7-1.8-1.80.8-1.8-1.3-1.61.3-1.5
Conditioned reinforcement - inactives1.82.13.9-2.00.11.7-1.70.7-1.7-1.70.5-1.8-1.5-1.11.0-1.7
Conditioned locomotion1.61.94.0-1.8-0.91.4-1.4-0.2-1.3-1.31.1-1.8-2.0-1.00.1-2.0
Intermittent access intake day 1-15 change3.63.56.9-2.4-0.91.9-1.90.0-2.0-2.01.1-2.5-2.6-1.80.5-2.6
Intermittent access intake escalation3.73.77.7-2.4-1.21.9-1.9-0.1-2.0-2.01.1-2.6-2.7-1.70.3-2.8
Intermittent access intake escalation 21.71.63.6-1.7-0.91.1-1.1-0.2-1.3-1.30.6-1.7-1.9-1.20.1-1.9
Intermitt. access day 1 inactive lever presses0.20.30.8-0.1-0.7-0.30.3-0.70.20.2-0.8-0.0-0.40.7-0.9-0.3
Intermitt. access day 15 inactive lever presses1.71.94.9-1.8-1.41.2-1.2-0.4-1.1-1.10.3-1.8-2.2-0.3-0.4-2.2
Intermitt. access escalation Index0.30.20.50.50.7-0.30.30.60.30.30.40.50.7-0.20.30.7
Intermittent access day 1 total infusions0.70.81.8-0.91.01.0-1.00.9-1.0-1.00.2-0.8-0.2-1.01.3-0.4
Intermittent access day 15 total infusions5.25.89.4-3.0-0.12.7-2.70.8-2.7-2.71.5-3.1-2.7-2.51.6-2.9
Intermittent access terminal intake (last 3 days)2.83.05.3-2.3-0.21.9-1.90.5-2.0-2.00.8-2.3-2.0-1.81.0-2.2
Intermittent access total infusions2.02.23.3-1.80.61.7-1.71.0-1.7-1.70.7-1.7-1.2-1.71.5-1.4
Intermittent access day 1 locomotion0.40.50.7-0.70.50.8-0.80.6-0.8-0.80.4-0.7-0.3-0.80.8-0.4
Intermittent access day 15 total locomotion1.81.94.0-1.8-0.81.4-1.40.0-1.5-1.50.8-1.9-1.9-1.00.2-2.0
Intermittent access total locomotion0.20.30.4-0.70.40.6-0.60.6-0.6-0.60.2-0.5-0.2-0.50.5-0.4
Intermittent access standard deviation1.92.13.8-1.8-0.61.5-1.50.2-1.4-1.41.2-1.9-1.9-1.40.5-1.9
Cocaine induced anxiety0.80.92.60.91.2-0.70.70.90.70.7-0.11.21.60.40.61.4
Post-drug Anxiety0.50.61.00.80.1-0.90.9-0.10.90.9-0.31.00.91.0-0.40.9
Baseline Anxiety0.30.31.1-0.2-1.0-0.00.0-0.90.10.1-0.1-0.3-0.80.3-0.8-0.6
Lifetime Intake1.51.72.8-1.70.41.5-1.50.7-1.5-1.50.5-1.6-1.1-1.51.2-1.4
Incentive Sensitization - Responses4.34.37.9-2.8-0.12.3-2.30.8-2.3-2.31.2-2.7-2.3-2.01.4-2.6
Incentive Sensitization - Breakpoint4.54.58.2-2.9-0.12.3-2.30.8-2.4-2.41.3-2.7-2.4-2.01.4-2.6
Progressive ratio test 1 active lever presses1.21.32.2-1.50.31.3-1.30.6-1.4-1.40.3-1.4-1.0-1.20.9-1.2
Progressive ratio test 1 breakpoint1.11.12.1-1.40.21.2-1.20.5-1.3-1.30.3-1.3-1.0-1.10.8-1.2
Progressive ratio test 1 inactive lever presses1.51.63.2-1.80.21.5-1.50.8-1.5-1.50.3-1.5-1.2-1.00.9-1.4
Progressive ratio test 2 active lever presses4.64.98.2-2.90.02.5-2.50.7-2.5-2.51.0-2.8-2.4-2.41.5-2.6
Progressive ratio test 2 breakpoint5.35.89.9-3.10.12.7-2.70.9-2.8-2.81.2-3.0-2.5-2.61.7-2.8
Progressive ratio test 2 inactive lever presses1.61.94.1-2.0-0.21.4-1.40.4-1.5-1.50.5-1.8-1.6-1.10.6-1.8
Total sessions with >9 infusions0.40.50.9-0.9-0.20.7-0.70.1-0.6-0.60.5-0.9-0.9-0.70.2-1.0
Short access day 1 total inactive lever presses0.70.82.3-1.4-1.10.5-0.5-0.2-0.5-0.5-0.2-1.1-1.40.3-0.5-1.5
Short access day 10 total inactive lever presses1.21.32.21.1-0.3-1.21.2-0.71.31.3-1.21.31.01.5-1.11.1
Short access day 1 total infusions0.00.00.1-0.2-0.20.1-0.1-0.2-0.1-0.10.1-0.2-0.3-0.3-0.1-0.3
Short access day 10 total infusions0.10.10.3-0.4-0.40.3-0.3-0.4-0.2-0.2-0.3-0.4-0.6-0.2-0.1-0.5
Short access total infusions0.70.71.3-1.20.30.9-0.90.4-1.0-1.00.3-1.0-0.8-1.00.7-0.9
Short access day 1 locomotion0.00.00.10.10.1-0.10.10.20.10.10.20.10.1-0.3-0.10.1
Short access day 10 total locomotion0.20.20.30.50.1-0.50.5-0.00.50.5-0.50.60.50.5-0.40.5
Short access total locomotion0.20.20.50.5-0.4-0.50.5-0.30.60.6-0.40.50.30.6-0.70.3
Compulsive drug intake1.11.12.5-0.90.71.2-1.21.1-1.0-1.01.6-0.9-0.5-1.01.3-0.6
One hour access (0.3 mA shock)8.09.314.5-3.80.63.4-3.41.6-3.6-3.62.3-3.7-2.8-3.32.6-3.3
One hour access (shock baseline)2.12.44.3-2.1-0.01.7-1.70.5-1.9-1.90.6-1.9-1.7-1.61.0-1.9
Number of responses in last shaping day2.02.03.5-1.9-0.41.5-1.50.3-1.4-1.40.9-1.8-1.8-1.40.6-1.9
Context. condit. distance diff. score2.12.64.9-1.31.71.7-1.72.2-1.8-1.81.6-1.1-0.1-1.82.2-0.5
Locomotion velocity, session 13.33.59.11.5-2.3-2.12.1-1.82.02.0-0.81.30.12.7-3.00.5
Locomotion distance, session 10.30.41.20.4-0.5-0.70.7-0.50.60.6-1.10.50.10.8-0.90.2
Locomotion velocity, session 20.81.02.50.9-1.1-1.11.1-1.21.01.0-0.50.70.11.4-1.60.4
Locomotion distance, session 20.20.30.60.80.3-0.50.5-0.20.50.5-0.70.70.70.2-0.10.8
Locomotion velocity, session 30.20.30.5-0.30.40.6-0.60.3-0.6-0.60.6-0.4-0.2-0.70.6-0.2
Locomotion distance, session 31.01.12.6-0.51.41.1-1.11.2-1.1-1.10.8-0.60.2-1.51.60.0
Stereotopy head waving bouts, day 30.30.41.7-0.2-1.3-0.20.2-0.90.30.30.0-0.3-0.80.6-1.0-0.7
Stereotopy head waving duration, day 30.20.20.8-0.1-0.9-0.40.4-0.50.40.4-0.1-0.0-0.40.6-0.7-0.4
Locomotion velocity, session 70.91.03.8-0.22.00.7-0.71.6-0.7-0.70.10.11.1-0.91.50.7
Locomotion distance, session 70.81.03.1-0.41.70.8-0.81.6-0.9-0.90.2-0.20.7-1.01.40.4
Stereotopy head waving bouts, day 70.20.20.9-0.1-0.9-0.10.1-0.90.20.20.4-0.3-0.70.1-0.5-0.5
Stereotopy head waving duration, day 70.70.92.4-0.6-1.50.2-0.2-1.0-0.2-0.21.5-0.9-1.5-0.1-0.6-1.3
Locomotion velocity, session 80.20.20.4-0.60.40.6-0.60.5-0.6-0.60.3-0.5-0.3-0.50.5-0.4
Locomotion distance, session 80.60.82.9-0.21.70.6-0.61.5-0.7-0.70.10.10.9-0.91.40.6
Degree of sensitization distance0.60.61.50.60.8-0.60.60.60.60.6-1.01.01.20.50.11.1
Degree of sensitization stereotypy0.50.51.4-0.6-0.90.4-0.4-0.7-0.4-0.41.0-0.9-1.2-0.4-0.1-1.0
Condit. Reinf. active minus inactive responses0.60.61.51.20.2-0.80.8-0.00.80.8-0.21.11.00.7-0.41.2
Condit. Reinf. active-inactive response ratio0.70.71.30.9-1.0-0.90.9-1.01.01.0-0.30.70.11.0-1.10.4
Condit. Reinf. active responses0.30.41.20.51.10.2-0.21.1-0.2-0.20.50.40.9-0.30.70.8
Condit. Reinf. inactive responses0.81.02.6-0.51.51.0-1.01.6-1.1-1.10.8-0.40.4-0.91.30.1
Incentive salience index mean0.91.13.01.60.9-0.80.80.50.90.9-0.21.51.70.40.11.7
Condit. Reinf. lever presses1.21.63.81.80.9-1.21.20.41.11.1-0.81.71.90.7-0.11.9
Time in familiar zone, hab. session 10.20.20.6-0.4-0.80.2-0.2-0.4-0.0-0.00.2-0.5-0.70.3-0.6-0.7
Time in novel zone, hab. session 10.60.61.20.90.4-0.80.8-0.40.70.7-1.11.01.00.20.11.0
Total zone transitions, hab. session 10.00.10.4-0.2-0.10.0-0.0-0.0-0.2-0.2-0.7-0.1-0.2-0.1-0.1-0.2
Total locomotion distance, hab. session 10.91.33.81.20.3-1.21.2-0.31.01.0-1.91.41.30.9-0.61.3
Locomotion velocity, hab. session 11.31.95.01.50.6-1.41.4-0.21.21.2-2.21.71.71.0-0.61.7
Time in familiar zone, hab. session 20.40.41.10.3-1.1-0.60.6-0.80.70.70.10.1-0.40.9-1.0-0.2
Time in novel zone, hab. session 20.00.00.1-0.20.10.2-0.20.1-0.3-0.3-0.2-0.2-0.1-0.40.1-0.1
Total zone transitions, hab. session 20.20.30.90.4-1.0-0.60.6-0.90.50.5-0.10.2-0.30.4-0.6-0.1
Total locomotion distance, hab. session 20.30.50.80.8-0.4-0.90.9-0.70.70.7-0.60.70.40.6-0.60.6
Locomotion velocity, hab. session 20.50.61.01.00.1-0.90.9-0.50.80.8-0.91.00.80.6-0.30.9
Novel to familiar place preference ratio0.40.51.6-0.61.10.6-0.60.8-0.6-0.6-1.3-0.10.4-0.50.70.1
Novelty place preference0.50.51.8-0.71.00.6-0.60.7-0.7-0.7-1.3-0.20.3-0.50.7-0.0
Time in novel zone, NPP test0.40.42.0-0.50.90.5-0.50.6-0.5-0.5-1.4-0.10.4-0.40.60.1
Total zone transitions, NPP test0.50.71.31.10.1-1.01.0-0.20.90.9-0.61.00.90.6-0.21.0
Total locomotion distance, NPP test1.72.44.51.90.2-1.71.7-0.61.51.5-2.11.91.71.3-1.01.8
Locomotion velocity, NPP test1.62.34.21.90.6-1.61.6-0.31.41.4-2.11.91.91.2-0.72.0
Pavlov. Cond. lever latency1.11.44.3-1.3-1.80.5-0.5-1.2-0.5-0.50.5-1.4-2.1-0.1-0.8-1.9
Pavlov. Cond. magazine entry latency0.60.82.11.40.1-0.90.90.10.90.90.51.11.00.8-0.61.2
Pavlov. Cond. change in total contacts0.60.61.71.3-0.2-0.90.9-0.20.80.80.50.90.70.5-0.60.9
Pavlov. Cond. index score0.91.13.11.41.4-0.50.51.10.50.50.41.31.80.10.51.7
Pavlov. Cond. latency score1.21.54.31.41.8-0.50.51.40.50.50.11.42.1-0.00.92.0
Pavlov. Cond. lever contacts1.21.44.11.41.6-0.60.61.00.60.6-0.31.52.00.10.82.0
Pavlov. Cond. magazine entry number0.20.31.7-0.70.10.3-0.3-0.3-0.3-0.3-1.3-0.4-0.3-0.40.4-0.4
Pavlov. Cond. intertrial magazine entries0.40.40.9-0.51.00.7-0.70.8-0.7-0.70.3-0.30.2-0.81.0-0.0
Pavlov. Cond. lever-magazine prob. diff.1.11.43.71.61.3-0.80.80.90.80.80.21.51.90.40.41.9
Pavlov. Cond. response bias0.60.71.81.3-0.0-0.90.90.00.80.80.71.10.90.9-0.71.1
Bone: apparent density5.99.816.7-4.10.03.6-3.61.8-3.6-3.63.2-3.8-3.2-2.31.5-3.6
Bone surface3.96.811.4-3.3-0.82.8-2.80.6-2.8-2.82.9-3.3-3.2-1.70.7-3.4
Bone volume4.88.112.0-3.50.13.2-3.21.6-3.2-3.23.5-3.4-2.8-2.21.4-3.2
Bone: connectivity density3.35.110.0-3.2-0.62.4-2.40.7-2.5-2.52.0-2.9-2.7-1.30.6-3.0
Bone: cortical apparent density1.82.33.31.5-0.9-1.81.8-1.51.81.8-1.61.50.91.7-1.41.1
Bone: cortical area3.65.511.2-2.21.12.6-2.62.0-2.7-2.73.3-2.4-1.5-2.62.1-1.7
Bone: cortical porosity0.20.20.40.50.2-0.50.5-0.30.40.4-0.50.60.60.3-0.20.6
Bone: cortical porosity0.00.00.00.00.2-0.00.00.0-0.1-0.10.20.00.1-0.10.10.1
Bone: cortical thickness0.50.95.2-0.30.80.7-0.71.2-0.8-0.82.3-0.5-0.0-0.90.9-0.1
Bone: cortical thickness0.50.51.21.00.5-0.80.80.40.70.7-0.11.01.10.5-0.21.1
Bone: cortical tissue density1.82.43.41.5-0.9-1.81.8-1.51.81.8-1.61.50.91.8-1.51.1
Bone: elastic displacement3.13.56.21.4-1.7-2.02.0-2.22.12.1-1.91.50.52.4-2.50.8
Bone: elastic work1.92.45.00.9-1.5-1.61.6-2.01.61.6-2.01.10.22.1-2.20.4
Bone: endosteal estimation4.18.913.9-3.70.13.5-3.51.1-3.5-3.51.7-3.7-3.1-3.02.1-3.4
Bone: endosteal perimeter4.69.414.7-3.80.23.6-3.61.5-3.6-3.62.2-3.8-3.1-2.92.0-3.5
Bone: final force1.21.92.8-1.40.21.5-1.50.6-1.6-1.61.7-1.6-1.3-1.61.1-1.4
Bone: final moment1.21.93.1-1.5-0.31.5-1.50.2-1.5-1.51.6-1.7-1.7-1.40.7-1.7
Bone: marrow area4.39.314.6-3.80.13.6-3.61.1-3.6-3.61.7-3.8-3.2-3.02.1-3.5
Bone: maximum diameter7.814.219.8-4.50.94.4-4.42.5-4.4-4.43.6-4.4-3.3-3.83.0-3.8
Bone: maximum force2.54.46.9-2.4-0.12.3-2.30.8-2.4-2.42.1-2.6-2.3-2.21.3-2.4
Bone: maximum moment2.54.47.4-2.5-0.62.2-2.20.3-2.3-2.32.0-2.7-2.6-1.90.8-2.7
Bone: minimum diameter8.014.820.2-4.20.94.5-4.52.2-4.5-4.53.6-4.4-3.4-4.43.3-3.7
Bone: periosteal estimation5.310.915.5-3.90.53.8-3.81.8-3.9-3.92.9-3.9-3.1-3.42.4-3.4
Bone: periosteal perimeter4.87.911.4-3.21.13.3-3.32.0-3.4-3.42.4-3.1-2.2-3.12.5-2.6
Bone: post-yield work3.75.07.0-2.30.32.5-2.51.3-2.5-2.52.5-2.6-2.1-2.62.0-2.2
Bone: stiffness3.25.09.0-2.11.52.5-2.52.1-2.5-2.52.3-2.2-1.2-3.02.6-1.4
Bone: tissue strength0.50.52.1-0.3-1.5-0.20.2-1.10.20.20.2-0.5-1.20.1-0.8-0.9
Bone: trabecular number4.77.412.6-3.6-0.53.0-3.01.3-3.0-3.03.1-3.4-3.1-1.81.0-3.4
Bone: trabecular spacing1.82.34.72.20.4-1.71.7-0.31.71.7-0.92.01.80.9-0.52.0
Bone: trabecular thickness4.14.97.7-2.8-0.12.5-2.51.0-2.6-2.62.6-2.7-2.3-1.50.9-2.6
Bone: trabecular tissue density0.81.11.6-1.20.91.2-1.21.1-1.2-1.20.8-0.9-0.3-1.01.3-0.7
Breakpoint value in progressive ratio session0.80.92.6-0.61.40.9-0.91.6-0.9-0.91.1-0.30.4-0.91.30.1
Distance traveled before self-admin0.40.51.70.80.6-0.50.5-0.10.50.5-1.30.80.90.10.10.9
Distance traveled after self-admin0.10.10.4-0.3-0.2-0.10.10.10.20.2-0.10.0-0.00.6-0.5-0.2
Delta time in closed arm before/after self-admin0.20.20.50.70.2-0.40.40.10.40.4-0.10.40.4-0.40.20.6
Delta time in open arm before/after self-admin0.30.20.70.30.6-0.40.40.40.30.3-0.60.60.80.50.10.7
Diff in mean of infusions in LGA sessions0.30.30.9-0.20.90.5-0.51.0-0.4-0.40.5-0.10.3-0.60.70.2
Extinction: sum of active levers before priming0.50.51.2-0.30.60.7-0.71.0-0.7-0.71.1-0.4-0.0-0.70.8-0.1
Active lever presses in extinction session 61.11.03.1-0.71.80.8-0.81.6-0.6-0.60.4-0.20.7-1.21.70.3
Delta distance traveled before/after self-admin0.80.92.0-1.3-0.10.9-0.90.9-0.9-0.91.4-1.0-0.8-0.20.3-1.1
Delta ambulatory time before/after self-admin1.61.73.5-1.70.21.4-1.41.3-1.4-1.41.9-1.4-1.0-0.70.9-1.3
Time in closed arm before self-admin0.40.51.00.50.4-0.60.6-0.10.70.7-0.80.91.00.8-0.10.9
Time in closed arm after self-admin1.71.74.31.61.4-1.11.10.41.11.1-1.11.72.10.30.62.0
Time in open arm before self-admin0.20.20.9-0.2-1.0-0.10.1-0.6-0.0-0.00.3-0.4-0.80.2-0.7-0.6
Time in open arm after self-admin0.40.41.0-1.0-0.40.6-0.60.2-0.7-0.70.3-0.9-0.9-0.1-0.2-1.0
Sum of active levers in priming session hrs 5-60.60.62.10.3-0.9-0.80.8-0.50.80.80.20.4-0.01.2-1.50.1
Time to tail flick, vehicle, before self-admin1.11.12.60.8-0.9-1.31.3-0.81.21.2-0.50.90.41.5-1.60.5
Time to tail flick, vehicle, after self-admin1.31.35.3-0.12.30.6-0.61.6-0.6-0.6-0.40.31.3-1.02.10.9
Time to tail flick, test, before self-admin1.71.74.7-1.11.61.3-1.32.2-1.5-1.51.0-0.80.1-1.11.6-0.3
Time to tail flick, test, after self-admin0.40.40.60.70.1-0.80.8-0.10.70.7-0.30.80.70.8-0.50.7
Delta time to tail flick, vehicle, before/after SA3.83.712.8-0.93.11.8-1.82.4-1.6-1.60.3-0.70.9-2.43.60.4
Delta time to tail flick, test, before/after SA0.20.10.30.4-0.2-0.40.4-0.50.60.6-0.20.40.20.1-0.20.3
Ambulatory time before self-admin1.01.01.71.30.2-1.01.0-0.41.11.1-1.31.21.20.6-0.51.3
Ambulatory time after self-admin0.10.10.3-0.40.20.0-0.00.60.00.00.10.00.20.5-0.1-0.1
Total heroin consumption0.60.71.3-1.00.71.1-1.10.9-0.9-0.90.6-0.9-0.4-0.80.9-0.6
Area under the delay curve0.50.51.10.90.5-0.70.70.10.80.8-0.21.01.10.6-0.11.1
Delay disc. indifference point, 0s delay1.21.34.50.62.1-0.10.11.70.20.20.01.01.8-0.21.31.5
Delay disc. indifference point, 16s delay0.00.00.1-0.2-0.20.2-0.2-0.0-0.1-0.10.3-0.2-0.3-0.0-0.2-0.3
Delay disc. indifference point, 2s delay0.30.40.70.6-0.0-0.70.7-0.20.70.7-0.80.70.60.8-0.60.6
Delay disc. indifference point, 24s delay0.70.71.51.20.4-0.80.8-0.00.90.9-0.81.01.10.4-0.11.2
Delay disc. indifference point, 4s delay0.60.61.90.81.2-0.40.40.70.50.5-0.00.91.40.30.41.3
Delay disc. indifference point, 8s delay2.22.33.21.8-0.3-1.81.8-0.81.81.8-0.91.81.41.6-1.31.5
Delay discount exponential model param0.50.61.1-1.0-0.40.8-0.8-0.0-0.8-0.80.3-1.0-1.0-0.60.2-1.1
Delay discount hyperbolic model param0.60.61.1-1.0-0.30.8-0.80.0-0.9-0.90.4-1.0-1.0-0.70.3-1.0
Fecal boli incidents, locomotor time 10.30.41.20.21.1-0.10.10.90.10.1-0.40.50.9-0.11.00.7
Change in fecal boli incidents, locomotor task0.10.10.50.1-0.50.0-0.0-0.7-0.0-0.0-0.3-0.1-0.40.2-0.5-0.2
Time >=10cm from walls, locomotor time 14.04.07.2-1.51.82.2-2.22.1-2.3-2.32.3-1.7-0.6-2.42.7-0.8
Bouts of movement, locomotor time 10.30.31.1-0.70.70.4-0.40.8-0.4-0.40.3-0.5-0.1-0.81.0-0.3
Total resting periods, locomotor time 10.40.41.3-0.70.80.5-0.50.9-0.5-0.50.4-0.5-0.0-0.81.1-0.2
Rest time, locomotor task time 10.00.00.1-0.20.1-0.20.20.30.10.10.10.10.20.30.10.0
Distance moved, locomotor task time 10.10.20.50.70.5-0.00.0-0.3-0.0-0.0-0.50.40.5-0.30.20.7
Vertical activity count, locomotor time 10.10.10.2-0.0-0.30.3-0.3-0.3-0.2-0.2-0.2-0.3-0.5-0.2-0.4-0.3
Time >=10cm from walls, locomotor time 20.70.72.60.21.60.3-0.31.1-0.5-0.50.30.20.9-0.71.60.8
Bouts of movement, locomotor time 22.83.04.61.90.3-2.02.0-0.32.12.1-1.42.12.01.9-0.92.0
Total resting periods, locomotor time 22.83.04.71.90.5-2.02.0-0.22.02.0-1.42.22.11.6-0.62.1
Rest time, locomotor task time 20.30.41.30.21.1-0.10.10.70.20.2-0.20.50.9-0.51.10.7
Distance moved, locomotor task time 20.10.10.30.10.40.4-0.4-0.1-0.5-0.5-0.3-0.10.1-0.30.20.1
Vertical activity count, locomotor time 20.40.41.70.4-0.8-0.40.4-0.90.30.3-0.50.2-0.21.0-1.3-0.0
Weight adjusted by age0.30.30.90.3-0.1-0.60.60.30.60.6-0.30.60.51.0-0.60.4
Seeking ratio, delayed vs. immediate footshock0.10.10.5-0.00.70.1-0.10.5-0.2-0.2-0.1-0.00.3-0.60.70.2
Locomotion in novel chamber1.01.22.2-1.50.41.3-1.30.8-1.3-1.31.0-1.2-0.9-1.00.8-1.1
Locomotion in novel chamber post-restriction2.02.44.8-1.41.71.8-1.81.6-1.7-1.70.9-1.3-0.3-1.82.2-0.6
Progressive ratio0.60.72.2-0.41.30.7-0.71.0-0.7-0.7-0.2-0.30.3-1.11.50.1
Food seeking constrained by brief footshock2.83.56.5-1.90.62.2-2.21.1-2.2-2.21.0-2.1-1.6-2.61.8-1.7
Seeking ratio, punishment vs. effort0.20.20.6-0.3-0.60.4-0.4-0.5-0.4-0.40.5-0.6-0.8-0.3-0.3-0.7
Run reversals in cocaine runway, females0.50.51.90.4-0.9-0.70.7-0.50.70.7-0.30.50.01.3-1.40.1
Run reversals in cocaine runway, males0.00.00.20.20.0-0.10.1-0.20.10.1-0.30.00.0-0.30.40.1
Latency to leave start box in cocaine runway0.30.40.6-0.70.40.7-0.70.3-0.8-0.8-0.1-0.7-0.4-0.80.5-0.5
Latency to leave start box in cocaine runway, F0.10.10.4-0.30.30.3-0.3-0.1-0.2-0.2-0.6-0.3-0.1-0.60.5-0.1
Latency to leave start box in cocaine runway, M0.50.51.0-0.80.20.8-0.80.5-1.0-1.00.4-0.8-0.6-0.50.1-0.7
Cd content in liver0.30.31.30.1-1.1-0.20.2-1.10.20.20.2-0.2-0.80.2-0.7-0.5
Co content in liver1.41.74.90.4-2.0-1.11.1-1.81.11.1-0.90.3-0.71.7-2.2-0.4
Cu content in liver3.03.67.41.3-2.1-2.02.0-2.32.02.0-2.21.20.12.4-2.70.4
Fe content in liver3.13.74.92.2-1.1-2.22.2-2.02.22.2-2.21.91.11.9-1.91.5
K content in liver1.61.63.91.21.2-1.11.10.51.11.1-1.81.62.00.70.21.8
Mg content in liver1.71.72.81.50.2-1.51.5-0.51.51.5-1.41.71.51.2-0.71.6
Mn content in liver1.61.82.71.6-0.1-1.51.5-0.71.51.5-1.41.61.41.2-1.01.5
Na content in liver3.23.46.82.21.2-1.81.80.11.81.8-1.82.42.61.2-0.22.6
Rb content in liver0.20.20.70.00.80.2-0.20.4-0.2-0.2-0.70.10.5-0.50.80.4
Se content in liver19.123.131.55.3-2.9-5.65.6-4.55.65.6-4.54.92.75.1-5.23.7
Sr content in liver1.00.92.5-1.0-1.50.3-0.3-0.8-0.3-0.31.1-1.0-1.60.2-0.9-1.5
Zn content in liver8.59.313.73.7-0.6-3.53.5-1.93.53.5-3.13.62.73.0-2.53.2