Hub : Genes

Ccdc51

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability ENSRNOG00000020688 0.05 0.03 8.9e-07 0.05 0.05 0.05 0.05 1.7e-06 1.1e-06 1.9e-06 2.3e-06
2 BLA mRNA stability ENSRNOG00000020688 0.12 0.08 2.7e-06 0.11 0.09 0.1 0.09 1.2e-06 1.1e-05 3.8e-06 1.4e-05
3 Brain mRNA stability ENSRNOG00000020688 0.16 0.08 5.6e-16 0.16 0.16 0.15 0.17 1.9e-14 3.8e-15 3.7e-14 3.6e-15
4 IL mRNA stability ENSRNOG00000020688 0.24 0.16 1.7e-03 0.07 0.09 -0 0.06 8.5e-03 3.8e-03 4.5e-01 1.8e-02
5 LHb intron excision ratio chr8:109723207:109738090 0.15 0.1 9.2e-03 -0 0.04 -0.01 0.03 4.5e-01 4.9e-02 6.8e-01 8.6e-02
6 Liver gene expression ENSRNOG00000020688 0.08 0.05 3.2e-11 0.1 0.09 0.09 0.09 8.2e-11 8.3e-10 4.7e-10 3.1e-10
7 Liver mRNA stability ENSRNOG00000020688 0.16 0.08 0.0e+00 0.2 0.18 0.19 0.2 3.1e-22 4.3e-20 1.0e-20 2.4e-21
8 NAcc gene expression ENSRNOG00000020688 0.05 0.04 4.3e-04 0.03 0.04 0.03 0.02 4.4e-03 1.1e-03 2.1e-03 6.2e-03
9 NAcc mRNA stability ENSRNOG00000020688 0.1 0.06 3.9e-08 0.1 0.1 0.09 0.09 1.5e-07 1.1e-07 2.0e-07 1.7e-07
10 PL intron excision ratio chr8:109723207:109738090 0.06 0.05 7.3e-03 0.02 0.01 0.02 0.02 6.2e-03 4.4e-02 1.2e-02 9.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail0.30.82.11.11.51.10.5-0.90.80.70.70.70.7
BMI without tail1.42.84.71.82.21.81.5-1.81.61.41.71.71.2
Body weight4.820.228.85.25.45.13.7-4.35.04.84.44.40.6
Epididymis fat weight0.20.40.60.70.80.80.4-0.50.80.70.50.50.0
Glucose0.60.92.30.60.80.61.1-1.10.70.60.90.91.5
Heart weight1.92.84.32.11.82.10.9-1.22.02.11.41.5-1.2
Left kidney weight1.13.26.31.51.91.51.9-2.01.41.31.81.72.5
Right kidney weight0.51.45.30.71.00.71.3-1.30.60.71.11.12.3
Tail length5.717.221.24.54.44.53.9-4.24.64.44.34.31.0
Length with tail7.627.834.85.95.85.84.7-5.25.95.85.45.40.7
Length without tail5.211.415.53.93.73.82.8-3.23.83.93.33.4-0.1
Liver weight, left0.20.41.30.20.20.31.0-0.70.30.40.70.61.1
Liver weight, right1.62.73.61.41.51.61.9-1.91.41.51.81.71.7
Parametrial fat weight1.22.32.71.51.61.51.6-1.61.61.41.61.61.1
Retroperitoneal fat weight0.51.72.21.21.11.21.4-1.41.51.31.31.31.1
Intraocular pressure0.91.32.01.00.81.21.4-1.21.41.21.31.30.3
Extensor digitorum longus weight0.20.81.3-0.7-0.7-0.8-1.11.1-0.7-0.9-1.0-1.0-1.1
Soleus weight3.08.711.73.33.43.32.5-2.93.23.23.03.00.5
Tibialis anterior weight0.00.10.30.20.20.2-0.30.10.10.0-0.1-0.1-0.6
Tibia length5.816.222.14.44.74.33.7-4.24.24.14.14.11.7
Number of licking bursts0.70.93.4-0.4-0.6-0.4-1.11.0-0.5-0.6-0.9-0.8-1.8
Food consumed during 24 hour testing period1.21.52.01.41.41.31.0-1.21.41.31.21.20.1
Times rat made contact with spout0.60.70.91.01.00.90.6-0.71.01.00.80.8-0.4
Mean time between licks in bursts1.21.72.0-1.4-1.4-1.4-1.31.3-1.3-1.3-1.4-1.4-0.4
Mean num. licks in bursts1.41.73.11.01.21.01.6-1.51.11.21.41.31.8
Std. dev. time between licks in bursts5.66.78.7-2.3-2.5-2.4-3.02.9-2.5-2.4-2.8-2.8-2.3
Water consumed over 24 hours0.20.21.50.20.10.1-0.60.40.00.1-0.3-0.3-1.2
Indifference point 0 sec1.62.53.81.41.41.42.0-1.81.31.41.81.81.4
Indifference point AUC0.30.42.20.10.30.30.8-0.70.30.20.50.51.5
Indifference point function ln k0.20.30.6-0.6-0.6-0.8-0.70.6-0.6-0.5-0.7-0.70.1
Indifference point function log k0.20.30.6-0.6-0.6-0.8-0.70.6-0.6-0.5-0.7-0.70.1
Delay discounting total patch changes 0 sec1.52.53.41.51.51.51.9-1.71.51.51.81.81.0
Delay discounting total patch changes 12 sec1.11.41.71.21.11.21.3-1.31.21.21.31.30.5
Delay discounting total patch changes 18 sec2.43.24.31.61.61.72.1-1.91.91.71.91.91.2
Delay discounting total patch changes 24 sec2.53.13.71.91.91.91.7-1.81.91.91.81.80.5
Delay discounting total patch changes 6 sec0.60.92.60.50.50.61.3-1.10.60.61.01.01.6
Delay discounting time to switch 0 sec0.30.52.2-0.3-0.5-0.4-0.90.8-0.3-0.5-0.7-0.6-1.5
Delay discounting water rate 0 sec0.10.20.40.50.40.50.4-0.40.50.60.50.50.0
Delay discounting water rate 12 sec0.10.20.20.50.50.50.3-0.40.40.40.40.40.2
Delay discounting water rate 18 sec0.10.10.40.10.10.0-0.50.3-0.2-0.1-0.3-0.2-0.6
Delay discounting water rate 24 sec0.50.71.21.00.91.10.7-0.81.01.00.80.8-0.1
Delay discounting water rate 6 sec0.20.30.50.50.60.50.6-0.60.60.70.50.60.7
Locomotor activity4.77.59.23.03.02.92.7-2.82.82.92.92.90.8
Locomotor testing distance4.16.88.12.82.82.72.6-2.72.62.72.82.81.0
Locomotor testing rearing0.00.10.10.30.20.20.3-0.20.10.30.30.3-0.3
Light reinforcement 10.50.91.21.11.01.10.9-1.00.90.91.01.00.4
Light reinforcement 20.20.32.1-0.5-0.4-0.50.1-0.1-0.5-0.4-0.1-0.21.5
Reaction time number correct0.50.81.0-0.9-1.0-0.9-0.91.0-0.7-0.7-1.0-0.9-0.8
Reaction time mean minus median0.10.20.50.30.50.40.4-0.50.00.20.40.40.7
Reaction time mean minus median AUC0.30.40.70.50.70.60.7-0.70.30.40.60.60.8
Reaction time num false alarms0.20.30.5-0.7-0.7-0.6-0.40.6-0.6-0.7-0.5-0.5-0.2
Reaction time num false alarms AUC0.00.00.1-0.3-0.3-0.20.00.1-0.2-0.3-0.1-0.10.2
Reaction time trials correct on left0.50.81.0-0.9-1.0-0.9-0.91.0-0.7-0.7-1.0-0.9-0.8
Reaction time trials on left0.60.81.1-0.9-1.1-1.0-0.91.0-0.7-0.7-1.0-0.9-0.8
Reaction time mean0.00.00.2-0.1-0.20.00.2-0.10.00.20.10.10.4
Reaction time mean AUC0.00.10.4-0.2-0.2-0.10.2-0.1-0.00.10.10.10.6
Median of all reaction times0.00.00.1-0.1-0.3-0.10.1-0.00.10.20.00.00.2
Reaction time omissions0.20.20.5-0.5-0.7-0.4-0.30.5-0.4-0.4-0.4-0.4-0.6
Reaction time false alarm rate0.00.00.0-0.00.00.00.2-0.1-0.1-0.20.10.10.2
Reaction time premature initiation rate2.02.73.91.82.01.71.6-1.71.61.61.71.70.7
Reaction time premature initiations0.81.11.81.21.31.01.0-1.11.11.11.11.10.2
Std. dev. reaction times0.20.30.90.30.30.40.7-0.60.20.30.50.51.0
Reaction time trials completed0.60.81.1-0.9-1.1-1.0-0.91.0-0.7-0.7-1.0-0.9-0.8
Reaction time trials AUC0.71.01.4-1.1-1.2-1.1-1.01.1-0.8-0.8-1.1-1.1-0.7
Social response proportion0.40.51.10.70.70.60.6-0.60.71.00.70.7-0.2
Social responses0.40.60.70.80.90.60.8-0.80.40.80.80.80.5
Social time0.81.02.6-0.5-0.7-0.8-1.31.1-0.9-0.7-1.0-1.0-1.6
Conditioned locomotion2.22.63.8-1.9-1.9-1.9-1.21.5-1.8-1.8-1.6-1.60.2
Cocaine response after cond. corrected0.40.42.70.70.40.7-0.30.10.50.60.10.1-1.6
Cocaine response after cond. not corrected1.31.52.41.61.41.50.6-0.91.31.41.01.1-0.9
Cocaine response before conditioning1.41.72.41.11.41.01.4-1.51.11.11.31.31.5
Saline control response2.02.74.21.31.31.32.1-1.81.51.51.81.81.7
Condit. Reinf. active minus inactive responses1.51.92.91.51.71.51.2-1.31.61.51.31.30.3
Condit. Reinf. active-inactive response ratio1.11.22.01.31.41.30.8-1.01.21.11.01.0-0.0
Condit. Reinf. active responses1.52.12.91.61.71.51.3-1.41.71.61.41.40.2
Condit. Reinf. inactive responses0.00.00.0-0.1-0.0-0.10.1-0.00.00.10.00.0-0.0
Condit. Reinf. lever presses1.82.54.11.82.01.81.3-1.51.81.71.51.50.4
Condit. Reinf. lever reinforcers received1.62.33.21.71.81.61.3-1.51.71.71.51.50.2
Pavlov. Cond. lever latency0.20.30.6-0.6-0.8-0.7-0.40.6-0.5-0.6-0.5-0.5-0.3
Pavlov. Cond. magazine entry latency0.20.20.4-0.4-0.3-0.4-0.60.5-0.6-0.5-0.6-0.6-0.1
Pavlov. Cond. change in total contacts1.62.23.31.71.81.71.2-1.41.61.61.41.40.1
Pavlov. Cond. index score0.00.00.10.30.30.3-0.2-0.00.00.1-0.0-0.0-0.1
Pavlov. Cond. latency score0.00.00.10.20.30.2-0.2-0.0-0.10.0-0.1-0.1-0.1
Pavlov. Cond. lever contacts0.71.01.51.11.21.11.0-1.10.91.01.01.00.7
Pavlov. Cond. magazine entry number0.40.50.80.70.60.70.9-0.80.80.80.80.80.3
Pavlov. Cond. intertrial magazine entries0.40.50.7-0.7-0.8-0.7-0.60.8-0.5-0.6-0.7-0.7-0.7
Pavlov. Cond. lever-magazine prob. diff.0.00.00.10.20.30.2-0.20.0-0.00.0-0.1-0.1-0.1
Pavlov. Cond. response bias0.00.00.10.20.30.2-0.1-0.1-0.00.0-0.0-0.00.1
Conditioned reinforcement - actives0.30.20.4-0.6-0.5-0.5-0.40.4-0.6-0.6-0.5-0.50.2
Conditioned reinforcement - inactives1.92.14.6-1.0-1.1-1.1-1.81.7-1.1-1.2-1.6-1.5-2.1
Conditioned locomotion0.20.31.2-0.6-0.4-0.50.10.1-0.5-0.6-0.2-0.21.1
Intermittent access intake day 1-15 change1.41.43.8-0.7-0.9-0.8-1.51.3-0.7-0.8-1.2-1.2-2.0
Intermittent access intake escalation1.21.22.9-0.7-0.9-0.9-1.41.2-0.8-0.8-1.1-1.1-1.7
Intermittent access intake escalation 20.50.53.50.0-0.2-0.2-0.90.70.10.0-0.5-0.5-1.9
Intermitt. access day 1 inactive lever presses0.00.00.00.10.20.1-0.0-0.00.0-0.00.00.0-0.2
Intermitt. access day 15 inactive lever presses1.01.12.2-0.7-0.7-0.8-1.31.2-0.9-1.0-1.1-1.1-1.5
Intermitt. access escalation Index0.10.10.7-0.00.1-0.00.4-0.3-0.10.00.20.20.8
Intermittent access day 1 total infusions0.00.00.1-0.10.0-0.00.1-0.0-0.2-0.20.0-0.00.3
Intermittent access day 15 total infusions0.50.50.7-0.6-0.5-0.7-0.80.8-0.7-0.8-0.8-0.8-0.8
Intermittent access terminal intake (last 3 days)0.20.20.3-0.4-0.3-0.4-0.40.4-0.5-0.6-0.4-0.4-0.3
Intermittent access total infusions0.40.40.7-0.7-0.5-0.7-0.60.7-0.8-0.8-0.7-0.7-0.3
Intermittent access day 1 locomotion0.10.10.2-0.4-0.2-0.3-0.00.1-0.5-0.5-0.2-0.20.5
Intermittent access day 15 total locomotion0.70.71.2-1.1-1.0-1.1-0.50.6-0.9-0.9-0.7-0.80.7
Intermittent access total locomotion0.80.91.4-1.2-1.1-1.2-0.50.7-1.1-1.1-0.8-0.80.8
Intermittent access standard deviation0.50.53.80.50.30.3-0.60.40.30.2-0.2-0.1-2.0
Cocaine induced anxiety0.30.30.9-0.2-0.1-0.3-0.70.6-0.7-0.7-0.5-0.5-1.0
Post-drug Anxiety0.10.10.3-0.2-0.1-0.1-0.40.4-0.4-0.4-0.3-0.3-0.6
Baseline Anxiety0.50.50.9-0.9-1.0-0.9-0.60.7-0.6-0.6-0.7-0.70.2
Lifetime Intake0.30.40.5-0.7-0.6-0.7-0.50.6-0.7-0.7-0.6-0.60.0
Incentive Sensitization - Responses1.51.51.8-1.1-1.1-1.1-1.41.3-1.3-1.3-1.3-1.3-1.0
Incentive Sensitization - Breakpoint1.51.51.8-1.1-1.0-1.1-1.31.3-1.3-1.3-1.3-1.3-1.0
Progressive ratio test 1 active lever presses0.10.11.0-0.2-0.0-0.10.4-0.3-0.2-0.20.20.11.0
Progressive ratio test 1 breakpoint0.10.11.0-0.3-0.1-0.10.3-0.2-0.3-0.30.10.11.0
Progressive ratio test 1 inactive lever presses0.50.60.9-0.6-0.6-0.5-0.90.9-0.7-0.8-0.8-0.8-1.0
Progressive ratio test 2 active lever presses0.70.71.2-0.9-0.7-0.9-0.70.8-1.1-1.1-0.8-0.9-0.1
Progressive ratio test 2 breakpoint0.40.50.8-0.7-0.6-0.7-0.70.7-0.9-0.9-0.7-0.7-0.2
Progressive ratio test 2 inactive lever presses2.32.74.2-1.2-1.1-1.3-2.01.8-1.6-1.6-1.7-1.7-2.1
Total sessions with >9 infusions0.40.41.5-0.3-0.4-0.3-0.90.8-0.4-0.4-0.7-0.6-1.2
Short access day 1 total inactive lever presses5.25.76.8-2.5-2.6-2.4-2.52.6-2.3-2.3-2.6-2.6-1.2
Short access day 10 total inactive lever presses0.50.53.90.30.20.2-0.80.6-0.1-0.2-0.4-0.4-2.0
Short access day 1 total infusions1.11.11.4-1.1-1.1-1.0-1.11.2-1.1-1.1-1.2-1.2-0.5
Short access day 10 total infusions0.10.10.1-0.4-0.3-0.3-0.10.2-0.3-0.3-0.2-0.20.4
Short access total infusions0.60.71.0-1.0-1.0-0.9-0.60.7-0.9-0.8-0.8-0.80.4
Short access day 1 locomotion0.00.00.1-0.2-0.0-0.1-0.20.2-0.2-0.2-0.2-0.20.0
Short access day 10 total locomotion0.20.21.30.00.10.10.6-0.40.20.20.30.31.1
Short access total locomotion0.20.21.5-0.10.10.00.5-0.4-0.0-0.10.30.31.2
Compulsive drug intake0.20.21.5-0.5-0.5-0.40.2-0.1-0.2-0.2-0.1-0.11.2
One hour access (0.3 mA shock)0.20.30.5-0.6-0.5-0.6-0.10.3-0.6-0.6-0.3-0.40.7
One hour access (shock baseline)0.10.10.1-0.10.1-0.1-0.20.2-0.4-0.4-0.2-0.2-0.3
Number of responses in last shaping day0.90.91.2-0.8-0.7-0.8-1.11.0-1.1-1.1-1.0-1.0-1.0
Context. condit. distance diff. score0.00.00.00.00.10.0-0.10.1-0.0-0.0-0.0-0.0-0.2
Locomotion velocity, session 10.10.10.3-0.3-0.1-0.20.00.0-0.2-0.3-0.1-0.10.6
Locomotion distance, session 11.11.42.71.01.31.01.3-1.30.90.91.21.11.7
Locomotion velocity, session 20.30.30.4-0.5-0.4-0.5-0.70.6-0.6-0.7-0.6-0.6-0.1
Locomotion distance, session 20.20.32.1-0.2-0.0-0.20.2-0.3-0.3-0.30.0-0.01.5
Locomotion velocity, session 30.40.53.30.10.50.10.7-0.70.10.10.50.41.8
Locomotion distance, session 31.01.11.6-1.2-0.9-1.2-0.60.7-1.3-1.3-0.9-1.01.2
Stereotopy head waving bouts, day 30.30.43.20.30.10.3-0.60.40.20.2-0.2-0.2-1.8
Stereotopy head waving duration, day 30.20.31.20.60.30.60.1-0.10.60.60.30.3-1.1
Locomotion velocity, session 70.30.42.00.10.30.10.8-0.60.20.20.50.51.4
Locomotion distance, session 70.81.11.6-1.3-1.1-1.3-0.60.8-1.2-1.2-0.9-0.90.8
Stereotopy head waving bouts, day 70.00.00.2-0.2-0.2-0.10.1-0.1-0.1-0.00.00.00.4
Stereotopy head waving duration, day 70.40.40.60.60.60.60.7-0.70.60.70.70.70.6
Locomotion velocity, session 80.40.52.40.40.70.40.7-0.80.30.30.50.51.6
Locomotion distance, session 80.71.05.80.30.70.41.1-1.10.30.20.80.72.4
Degree of sensitization distance1.01.01.41.10.91.10.9-0.91.21.11.01.0-0.2
Degree of sensitization stereotypy0.30.31.20.20.20.20.7-0.60.30.30.50.51.1
Condit. Reinf. active minus inactive responses0.10.21.10.30.20.3-0.10.10.40.40.00.0-1.0
Condit. Reinf. active-inactive response ratio0.30.42.10.50.40.5-0.10.10.60.60.10.2-1.5
Condit. Reinf. active responses0.10.10.6-0.1-0.2-0.1-0.40.4-0.1-0.1-0.3-0.3-0.8
Condit. Reinf. inactive responses0.40.50.8-0.8-0.8-0.8-0.60.6-0.9-0.9-0.7-0.70.4
Incentive salience index mean0.10.10.4-0.2-0.2-0.2-0.50.4-0.2-0.3-0.4-0.4-0.6
Condit. Reinf. lever presses1.21.72.2-1.4-1.3-1.3-1.31.3-1.4-1.5-1.4-1.4-0.3
Time in familiar zone, hab. session 11.91.82.6-1.2-1.5-1.2-1.41.5-1.1-1.2-1.3-1.3-1.6
Time in novel zone, hab. session 10.80.81.20.91.10.90.9-0.90.91.00.90.90.6
Total zone transitions, hab. session 10.81.13.30.71.00.81.1-1.20.70.71.01.01.8
Total locomotion distance, hab. session 10.40.51.20.50.70.60.8-0.80.50.50.70.71.1
Locomotion velocity, hab. session 10.50.71.90.60.80.70.9-0.90.50.50.80.81.4
Time in familiar zone, hab. session 21.11.12.1-0.8-1.0-0.8-1.31.2-0.8-0.8-1.1-1.1-1.5
Time in novel zone, hab. session 20.20.20.50.20.30.10.6-0.50.30.20.40.40.7
Total zone transitions, hab. session 20.10.10.80.20.40.20.2-0.30.00.00.20.20.9
Total locomotion distance, hab. session 20.40.51.20.60.80.70.8-0.80.50.50.70.71.1
Locomotion velocity, hab. session 20.40.51.50.50.70.60.7-0.80.40.40.70.61.2
Novel to familiar place preference ratio2.12.27.90.60.70.72.0-1.70.90.91.51.42.8
Novelty place preference2.22.38.50.60.70.72.0-1.70.91.01.51.52.9
Time in novel zone, NPP test2.22.37.00.80.80.82.0-1.81.01.11.61.62.6
Total zone transitions, NPP test2.84.07.91.62.11.82.1-2.31.51.52.01.92.8
Total locomotion distance, NPP test1.11.62.01.21.41.31.3-1.41.11.11.31.31.3
Locomotion velocity, NPP test1.31.92.81.21.51.31.4-1.61.11.11.41.41.7
Pavlov. Cond. lever latency4.86.27.82.62.42.62.6-2.52.72.82.72.70.7
Pavlov. Cond. magazine entry latency6.58.39.7-2.8-2.9-2.9-3.13.1-2.9-3.0-3.1-3.1-1.6
Pavlov. Cond. change in total contacts1.92.12.5-1.3-1.4-1.4-1.61.6-1.3-1.4-1.5-1.5-1.3
Pavlov. Cond. index score6.48.29.5-2.8-2.8-2.8-3.13.0-2.9-3.0-3.1-3.1-1.6
Pavlov. Cond. latency score6.17.89.1-2.8-2.8-2.8-2.92.9-2.9-3.0-3.0-3.0-1.3
Pavlov. Cond. lever contacts2.73.24.0-1.8-1.7-1.8-1.91.8-1.9-2.0-1.9-1.9-0.6
Pavlov. Cond. magazine entry number7.39.110.33.03.13.03.2-3.23.13.13.23.21.6
Pavlov. Cond. intertrial magazine entries0.30.30.40.50.50.60.7-0.60.60.60.60.60.4
Pavlov. Cond. lever-magazine prob. diff.6.07.69.4-2.6-2.6-2.6-3.13.0-2.7-2.8-3.0-3.0-1.9
Pavlov. Cond. response bias7.08.610.3-2.9-2.9-2.9-3.23.2-3.0-3.0-3.2-3.2-1.8
Bone: apparent density0.20.31.8-0.00.1-0.10.7-0.50.20.20.40.41.3
Bone surface0.10.10.2-0.3-0.3-0.5-0.20.2-0.4-0.4-0.3-0.30.5
Bone volume0.00.10.6-0.2-0.1-0.30.1-0.1-0.2-0.2-0.0-0.00.7
Bone: connectivity density0.20.42.0-0.7-0.6-0.60.4-0.1-0.4-0.4-0.0-0.11.4
Bone: cortical apparent density0.10.20.3-0.5-0.6-0.5-0.20.3-0.5-0.4-0.3-0.30.2
Bone: cortical area0.71.04.1-0.3-0.5-0.4-1.41.1-0.5-0.5-1.0-0.9-2.0
Bone: cortical porosity0.20.21.4-0.3-0.3-0.20.6-0.3-0.10.00.30.31.2
Bone: cortical porosity0.20.31.5-0.5-0.5-0.40.5-0.1-0.3-0.20.10.01.2
Bone: cortical thickness0.40.74.70.50.30.3-0.90.50.30.3-0.3-0.3-2.2
Bone: cortical thickness0.00.00.1-0.0-0.1-0.1-0.20.2-0.0-0.0-0.2-0.1-0.4
Bone: cortical tissue density0.10.20.3-0.6-0.6-0.5-0.10.3-0.5-0.4-0.3-0.30.3
Bone: elastic displacement0.10.21.10.30.20.2-0.30.20.30.3-0.1-0.0-1.0
Bone: elastic work0.30.30.60.80.80.60.0-0.30.60.70.30.4-0.6
Bone: endosteal estimation0.10.20.60.20.20.20.6-0.50.30.30.40.40.8
Bone: endosteal perimeter0.91.82.3-1.5-1.5-1.5-1.21.3-1.5-1.5-1.4-1.4-0.1
Bone: final force0.61.01.81.31.21.20.4-0.61.21.20.80.8-1.0
Bone: final moment0.81.32.31.51.41.40.4-0.71.31.30.90.9-1.1
Bone: marrow area0.10.20.70.20.20.30.6-0.50.30.30.50.50.8
Bone: maximum diameter0.61.12.3-0.7-0.8-0.7-1.41.2-0.8-0.8-1.1-1.1-1.5
Bone: maximum force0.50.81.31.11.01.10.5-0.71.11.10.80.8-0.5
Bone: maximum moment0.50.91.51.21.11.20.5-0.71.11.20.80.9-0.6
Bone: minimum diameter0.50.91.1-0.9-0.9-0.9-1.01.0-0.9-0.9-1.0-1.0-0.5
Bone: periosteal estimation0.00.00.20.00.00.0-0.30.2-0.00.0-0.1-0.1-0.5
Bone: periosteal perimeter1.22.02.4-1.4-1.4-1.4-1.61.5-1.4-1.4-1.5-1.5-0.9
Bone: post-yield work0.00.00.20.10.20.10.2-0.20.10.10.20.20.4
Bone: stiffness0.10.20.30.50.40.40.3-0.40.50.50.40.4-0.1
Bone: tissue strength2.01.93.01.71.61.70.8-1.11.61.61.21.3-0.8
Bone: trabecular number0.60.92.3-1.2-1.0-1.2-0.20.4-1.0-1.0-0.6-0.61.5
Bone: trabecular spacing1.11.42.31.51.31.50.4-0.71.31.30.90.9-1.4
Bone: trabecular thickness0.30.42.60.10.20.00.7-0.70.10.20.50.41.6
Bone: trabecular tissue density0.30.40.60.60.70.60.8-0.70.60.50.70.70.6
Breakpoint value in progressive ratio session0.20.20.50.30.40.50.6-0.50.20.30.50.50.7
Distance traveled before self-admin0.30.31.5-0.1-0.3-0.3-0.70.6-0.1-0.0-0.5-0.4-1.2
Distance traveled after self-admin0.40.50.7-0.6-0.5-0.8-0.80.7-0.6-0.6-0.7-0.7-0.7
Delta time in closed arm before/after self-admin0.20.20.6-0.6-0.7-0.5-0.30.4-0.4-0.3-0.4-0.40.4
Delta time in open arm before/after self-admin0.20.20.30.40.50.30.5-0.50.40.30.50.50.4
Diff in mean of infusions in LGA sessions0.40.43.10.30.10.3-0.70.5-0.1-0.1-0.3-0.3-1.8
Extinction: sum of active levers before priming0.20.20.80.10.10.20.5-0.4-0.10.00.30.30.9
Active lever presses in extinction session 60.70.71.90.50.70.41.0-0.90.50.60.80.81.4
Delta distance traveled before/after self-admin0.10.10.3-0.30.1-0.30.00.0-0.4-0.5-0.1-0.10.5
Delta ambulatory time before/after self-admin0.40.40.80.60.90.50.8-0.80.40.30.70.70.8
Time in closed arm before self-admin1.21.32.01.31.21.21.0-1.11.41.31.21.2-0.0
Time in closed arm after self-admin0.00.00.1-0.0-0.30.0-0.20.10.20.2-0.1-0.1-0.3
Time in open arm before self-admin0.80.91.4-1.0-0.9-1.0-0.90.9-1.2-1.0-1.0-1.0-0.3
Time in open arm after self-admin0.40.42.4-0.6-0.3-0.70.4-0.1-0.5-0.5-0.0-0.11.6
Sum of active levers in priming session hrs 5-60.80.80.90.80.90.81.0-1.00.80.80.90.90.7
Time to tail flick, vehicle, before self-admin1.71.82.61.41.21.51.3-1.31.41.61.41.40.4
Time to tail flick, vehicle, after self-admin0.70.81.31.21.01.00.3-0.51.00.90.70.7-1.1
Time to tail flick, test, before self-admin0.60.62.50.30.40.41.0-0.90.50.30.70.71.6
Time to tail flick, test, after self-admin0.10.10.6-0.0-0.0-0.1-0.40.3-0.3-0.2-0.3-0.3-0.8
Delta time to tail flick, vehicle, before/after SA0.70.71.9-0.4-0.5-0.5-1.00.9-0.6-0.7-0.8-0.8-1.4
Delta time to tail flick, test, before/after SA0.50.51.0-0.5-0.5-0.5-0.90.8-0.7-0.6-0.7-0.7-1.0
Ambulatory time before self-admin0.50.51.4-0.4-0.6-0.6-0.90.8-0.4-0.4-0.7-0.7-1.2
Ambulatory time after self-admin0.10.10.3-0.3-0.1-0.5-0.10.2-0.3-0.3-0.2-0.20.2
Total heroin consumption0.70.91.91.21.41.00.6-0.80.90.90.90.9-0.6
Area under the delay curve1.41.52.4-1.5-1.2-1.4-0.80.9-1.5-1.5-1.1-1.10.8
Delay disc. indifference point, 0s delay0.00.00.1-0.2-0.2-0.10.00.0-0.2-0.1-0.0-0.10.4
Delay disc. indifference point, 16s delay0.70.71.0-1.0-0.9-1.0-0.50.6-1.0-1.0-0.7-0.70.6
Delay disc. indifference point, 2s delay0.20.20.3-0.5-0.3-0.5-0.30.3-0.6-0.6-0.4-0.40.3
Delay disc. indifference point, 24s delay0.60.60.9-0.9-0.8-1.0-0.50.6-0.9-0.9-0.7-0.70.5
Delay disc. indifference point, 4s delay1.51.52.4-1.4-1.2-1.3-1.01.1-1.6-1.6-1.2-1.20.0
Delay disc. indifference point, 8s delay1.51.62.3-1.5-1.3-1.5-0.81.0-1.5-1.5-1.1-1.20.7
Delay discount exponential model param1.71.82.81.61.41.60.9-1.11.71.71.31.3-0.6
Delay discount hyperbolic model param1.71.82.81.61.31.50.9-1.11.71.71.21.3-0.6
Fecal boli incidents, locomotor time 10.40.40.70.80.60.80.5-0.60.60.60.70.7-0.2
Change in fecal boli incidents, locomotor task0.00.00.2-0.10.2-0.00.2-0.10.10.10.00.00.5
Time >=10cm from walls, locomotor time 10.20.20.6-0.6-0.6-0.6-0.00.2-0.2-0.3-0.3-0.30.8
Bouts of movement, locomotor time 10.00.00.10.30.30.20.1-0.20.10.10.20.2-0.1
Total resting periods, locomotor time 10.00.00.10.20.20.20.1-0.10.10.00.10.1-0.1
Rest time, locomotor task time 10.50.50.8-0.8-0.9-0.7-0.50.6-0.8-0.8-0.7-0.70.2
Distance moved, locomotor task time 11.21.42.21.41.31.30.8-0.91.51.51.01.1-0.5
Vertical activity count, locomotor time 10.80.81.21.11.01.00.8-0.91.11.10.90.9-0.1
Time >=10cm from walls, locomotor time 21.21.31.71.21.01.21.1-1.11.31.31.21.20.4
Bouts of movement, locomotor time 20.10.10.6-0.1-0.1-0.1-0.50.4-0.1-0.2-0.4-0.4-0.8
Total resting periods, locomotor time 20.30.30.5-0.4-0.4-0.4-0.70.6-0.4-0.5-0.6-0.6-0.7
Rest time, locomotor task time 20.10.10.2-0.3-0.2-0.1-0.00.1-0.4-0.4-0.1-0.10.4
Distance moved, locomotor task time 20.91.01.91.21.01.00.6-0.81.41.40.90.9-0.5
Vertical activity count, locomotor time 20.10.10.20.30.20.20.2-0.20.50.50.20.3-0.1
Weight adjusted by age0.40.41.20.80.90.70.1-0.20.50.50.40.4-1.1
Seeking ratio, delayed vs. immediate footshock1.92.23.6-1.7-1.5-1.7-1.01.2-1.9-1.9-1.3-1.40.6
Locomotion in novel chamber0.20.20.7-0.2-0.3-0.4-0.60.5-0.4-0.2-0.5-0.4-0.8
Locomotion in novel chamber post-restriction0.80.91.20.80.80.81.1-1.11.01.01.01.01.0
Progressive ratio3.64.14.82.12.12.02.1-2.22.02.12.22.21.1
Food seeking constrained by brief footshock0.70.91.3-1.0-1.1-1.1-1.01.0-0.7-0.7-1.0-1.0-0.4
Seeking ratio, punishment vs. effort5.46.77.8-2.6-2.7-2.6-2.82.8-2.4-2.6-2.8-2.8-1.5
Run reversals in cocaine runway, females2.32.32.9-1.5-1.7-1.6-1.71.7-1.2-1.2-1.7-1.6-1.0
Run reversals in cocaine runway, males0.70.71.21.11.10.90.4-0.60.80.90.70.7-0.8
Latency to leave start box in cocaine runway0.50.50.80.80.80.90.6-0.70.80.70.70.7-0.0
Latency to leave start box in cocaine runway, F1.11.21.91.41.21.30.5-0.71.41.30.90.9-1.0
Latency to leave start box in cocaine runway, M0.20.21.2-0.4-0.2-0.30.2-0.1-0.4-0.5-0.0-0.11.1
Cd content in liver2.02.23.21.71.41.71.1-1.11.81.81.41.4-1.1
Co content in liver0.20.21.1-0.1-0.1-0.1-0.60.5-0.1-0.1-0.4-0.4-1.0
Cu content in liver3.84.65.42.22.22.22.3-2.32.22.22.32.31.0
Fe content in liver1.61.92.81.51.11.71.0-1.01.71.71.31.3-1.1
K content in liver1.01.01.40.91.01.11.0-1.10.80.81.01.01.2
Mg content in liver0.10.10.90.00.20.20.1-0.3-0.2-0.20.10.11.0
Mn content in liver0.91.12.90.61.00.81.2-1.20.60.61.01.01.7
Na content in liver0.50.50.90.60.50.70.9-0.80.70.70.80.80.5
Rb content in liver0.91.12.81.10.61.10.5-0.41.31.30.80.8-1.7
Se content in liver0.10.10.20.30.10.40.2-0.30.20.20.30.30.3
Sr content in liver0.10.10.70.00.3-0.00.1-0.2-0.1-0.10.00.00.8
Zn content in liver4.44.85.92.32.22.42.2-2.32.22.22.32.31.1