Dpf1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000020687 0.21 0.14 1.3e-10 0.21 0.19 0.2 0.18 1.1e-11 1.7e-10 5.1e-11 4.7e-10
2 BLA isoform ratio ENSRNOT00000098222 0.05 0.04 2.2e-03 0.03 0.05 0.04 0.04 7.3e-03 1.4e-03 2.1e-03 5.8e-03
3 BLA intron excision ratio chr1:84609784:84611337 0.06 0.04 9.4e-04 0.05 0.05 0.04 0.04 1.4e-03 9.1e-04 1.9e-03 2.4e-03
4 Brain gene expression ENSRNOG00000020687 0.27 0 0.0e+00 0.22 0.19 0.2 0.2 1.2e-19 2.3e-17 6.0e-18 2.6e-18
5 Brain isoform ratio ENSRNOT00000098222 0.09 0.09 3.1e-05 0.04 0.04 0.04 0.05 7.5e-05 8.1e-05 7.7e-05 2.0e-05
6 Brain intron excision ratio chr1:84609784:84611337 0.1 0.09 2.4e-05 0.05 0.04 0.05 0.05 2.2e-05 6.8e-05 3.0e-05 2.6e-05
7 NAcc gene expression ENSRNOG00000020687 0.13 0.08 2.9e-11 0.13 0.15 0.14 0.15 6.2e-10 5.6e-11 2.1e-10 4.8e-11
8 NAcc isoform ratio ENSRNOT00000028091 0.09 0.1 8.0e-04 0.02 0.03 0.02 0.03 5.8e-03 4.7e-03 1.8e-02 4.7e-03
9 NAcc isoform ratio ENSRNOT00000098222 0.09 0.07 1.3e-06 0.07 0.08 0.07 0.09 3.5e-06 1.0e-06 4.2e-06 6.8e-07
10 NAcc intron excision ratio chr1:84609784:84611337 0.05 0.04 2.6e-04 0.04 0.04 0.03 0.03 6.8e-04 5.2e-04 2.0e-03 2.0e-03
11 OFC gene expression ENSRNOG00000020687 0.46 0.19 4.0e-06 0.2 0.15 0.18 -0.01 1.6e-05 1.7e-04 4.4e-05 5.0e-01
12 PL alternative TSS ENSRNOT00000098222 0.11 0.08 8.5e-03 0.02 0.02 0.01 0.02 1.0e-02 8.7e-03 6.9e-02 1.4e-02
13 PL gene expression ENSRNOG00000020687 0.2 0.11 4.8e-13 0.16 0.16 0.14 0.16 4.4e-12 5.4e-12 2.0e-10 5.5e-12
14 PL intron excision ratio chr1:84609784:84611337 0.04 0.04 2.1e-03 0.03 0.02 0.03 0.03 2.3e-03 5.8e-03 1.5e-03 2.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail0.30.92.2-0.91.01.1-1.20.80.5-1.1-0.50.70.8-1.5-0.5-1.40.7
BMI without tail0.10.30.60.5-0.5-0.50.3-0.7-0.80.50.6-0.4-0.50.5-0.50.5-0.5
Body weight2.510.613.23.2-3.4-3.32.9-3.5-3.63.13.5-3.4-3.52.9-2.73.0-3.5
Epididymis fat weight0.00.00.1-0.10.20.2-0.10.10.1-0.0-0.10.10.1-0.4-0.1-0.30.1
Glucose0.30.40.6-0.60.70.7-0.50.60.6-0.6-0.70.80.7-0.70.5-0.50.7
Heart weight0.50.81.50.7-0.8-0.80.3-0.9-1.00.61.2-1.0-0.90.6-1.20.7-1.1
Left kidney weight2.26.411.72.3-2.3-2.21.6-2.6-3.02.13.2-2.9-2.71.4-3.41.6-2.9
Right kidney weight3.810.813.43.2-3.3-3.33.0-3.4-3.53.43.7-3.5-3.52.7-2.92.9-3.5
Tail length5.516.619.44.3-4.3-4.44.2-4.3-4.04.23.8-3.9-4.24.4-2.04.3-4.0
Length with tail8.129.534.35.5-5.8-5.85.5-5.6-5.45.65.2-5.4-5.65.8-2.85.9-5.5
Length without tail3.78.09.12.8-3.0-3.02.9-2.9-2.72.92.8-3.0-3.02.9-1.63.0-2.9
Liver weight, left0.30.51.2-0.60.70.8-1.10.40.1-1.1-0.10.40.5-1.0-0.8-1.10.2
Liver weight, right0.00.00.2-0.00.10.1-0.3-0.0-0.1-0.40.1-0.1-0.0-0.2-0.5-0.3-0.1
Parametrial fat weight0.71.42.7-1.41.31.3-1.61.21.0-1.2-0.81.01.1-1.50.1-1.31.0
Retroperitoneal fat weight1.44.68.0-2.12.32.4-2.52.01.6-2.6-1.72.02.0-2.8-0.1-2.71.8
Intraocular pressure0.10.10.60.10.0-0.10.60.00.10.2-0.40.30.10.00.80.20.4
Extensor digitorum longus weight0.20.80.9-0.90.90.9-0.80.90.9-0.9-1.00.91.0-0.80.7-0.80.9
Soleus weight0.71.93.6-1.21.31.2-0.81.41.7-1.2-1.71.61.5-0.91.9-0.91.6
Tibialis anterior weight0.00.00.2-0.10.20.2-0.30.0-0.0-0.4-0.00.10.1-0.3-0.4-0.3-0.0
Tibia length1.95.36.62.3-2.3-2.31.9-2.4-2.42.42.6-2.5-2.52.1-1.92.0-2.5
Number of licking bursts2.63.14.3-1.81.81.9-1.71.81.7-2.1-1.61.61.7-2.00.5-2.01.6
Food consumed during 24 hour testing period0.50.61.00.9-0.8-0.80.9-0.7-0.50.90.6-0.7-0.70.9-0.01.0-0.6
Times rat made contact with spout0.80.91.7-0.91.01.1-1.20.80.6-1.3-0.50.70.8-1.3-0.5-1.30.6
Mean time between licks in bursts0.10.10.30.2-0.3-0.30.1-0.3-0.30.30.5-0.5-0.40.3-0.60.2-0.5
Mean num. licks in bursts0.80.91.31.0-1.0-1.00.7-1.1-1.11.01.1-1.0-1.00.9-0.80.9-1.0
Std. dev. time between licks in bursts0.91.12.11.0-1.1-1.21.0-1.0-0.91.30.8-0.8-1.01.40.01.5-0.9
Water consumed over 24 hours0.60.72.40.6-0.6-0.50.2-0.8-1.10.41.1-0.9-0.90.2-1.50.3-1.0
Indifference point 0 sec0.20.30.50.6-0.5-0.50.3-0.6-0.60.20.6-0.6-0.60.4-0.70.4-0.7
Indifference point AUC0.40.51.0-0.60.80.8-1.00.60.5-0.9-0.50.70.7-0.9-0.0-0.80.6
Indifference point function ln k0.40.61.10.8-0.9-0.90.9-0.8-0.61.00.7-0.8-0.80.9-0.10.9-0.8
Indifference point function log k0.40.61.10.8-0.9-0.90.9-0.8-0.61.00.7-0.8-0.80.9-0.10.9-0.8
Delay discounting total patch changes 0 sec0.30.40.60.8-0.7-0.70.6-0.8-0.60.50.7-0.7-0.70.6-0.60.5-0.8
Delay discounting total patch changes 12 sec0.20.30.50.6-0.5-0.50.2-0.7-0.60.30.7-0.6-0.60.4-0.70.4-0.7
Delay discounting total patch changes 18 sec0.20.20.5-0.30.50.5-0.70.30.3-0.7-0.20.30.4-0.6-0.2-0.60.3
Delay discounting total patch changes 24 sec0.70.81.31.1-1.0-1.01.0-1.1-0.80.80.8-0.8-0.91.0-0.40.9-0.9
Delay discounting total patch changes 6 sec0.10.10.40.3-0.2-0.1-0.1-0.4-0.3-0.20.3-0.2-0.20.1-0.6-0.0-0.4
Delay discounting time to switch 0 sec0.91.32.4-1.31.11.0-0.91.31.3-0.7-1.31.31.2-0.61.6-0.61.3
Delay discounting water rate 0 sec0.60.91.7-1.01.01.0-1.01.00.8-1.3-0.80.90.9-1.20.1-1.20.8
Delay discounting water rate 12 sec0.71.11.51.2-1.1-1.11.1-1.1-1.00.80.9-1.0-1.11.0-0.71.0-1.1
Delay discounting water rate 18 sec0.50.72.5-0.70.60.50.10.91.1-0.5-1.20.90.8-0.11.6-0.31.0
Delay discounting water rate 24 sec0.20.30.60.4-0.6-0.50.6-0.4-0.60.10.6-0.7-0.60.4-0.80.3-0.6
Delay discounting water rate 6 sec0.20.30.60.5-0.5-0.60.8-0.3-0.20.80.2-0.3-0.40.70.40.6-0.3
Locomotor activity0.50.91.6-1.01.01.0-1.20.90.5-1.1-0.60.80.9-1.3-0.0-1.10.8
Locomotor testing distance0.91.41.7-1.21.31.3-1.31.31.1-1.1-1.11.21.2-1.30.7-1.21.2
Locomotor testing rearing1.72.74.3-1.81.71.8-2.01.71.3-2.1-1.31.61.6-1.80.3-1.81.5
Light reinforcement 10.10.30.4-0.30.50.5-0.50.30.4-0.6-0.50.60.5-0.60.3-0.50.5
Light reinforcement 25.87.710.1-2.82.82.7-2.43.03.0-2.3-3.13.03.0-2.32.9-2.13.2
Reaction time number correct0.20.31.6-0.30.20.4-0.80.1-0.2-0.60.4-0.2-0.0-0.6-1.3-0.7-0.2
Reaction time mean minus median0.10.20.40.4-0.4-0.40.4-0.4-0.40.30.5-0.6-0.50.3-0.50.3-0.5
Reaction time mean minus median AUC0.20.30.60.4-0.5-0.50.4-0.5-0.60.30.7-0.8-0.60.4-0.80.3-0.7
Reaction time num false alarms1.11.52.0-1.31.31.3-1.41.21.0-1.4-1.11.21.2-1.40.4-1.41.1
Reaction time num false alarms AUC1.52.02.8-1.51.51.6-1.51.41.3-1.5-1.31.41.4-1.70.5-1.61.3
Reaction time trials correct on left0.20.31.6-0.30.20.4-0.80.1-0.2-0.60.4-0.2-0.0-0.6-1.3-0.7-0.2
Reaction time trials on left0.20.31.6-0.40.30.4-0.80.2-0.2-0.60.4-0.10.0-0.6-1.3-0.8-0.2
Reaction time mean0.10.10.2-0.40.30.3-0.10.40.3-0.2-0.30.10.3-0.40.1-0.50.3
Reaction time mean AUC0.20.30.6-0.70.60.6-0.40.60.5-0.4-0.40.30.5-0.70.1-0.80.5
Median of all reaction times0.20.30.5-0.60.60.5-0.30.60.5-0.4-0.50.40.5-0.70.3-0.70.6
Reaction time omissions0.30.40.7-0.90.60.6-0.70.70.5-0.8-0.40.40.5-0.60.1-0.60.5
Reaction time false alarm rate0.91.31.9-1.11.21.1-0.91.11.2-1.0-1.41.31.3-1.01.3-1.01.3
Reaction time premature initiation rate0.10.10.30.3-0.3-0.30.5-0.20.00.3-0.0-0.2-0.10.50.50.6-0.0
Reaction time premature initiations0.00.00.00.0-0.1-0.1-0.0-0.0-0.0-0.10.1-0.2-0.10.1-0.20.1-0.1
Std. dev. reaction times0.10.10.30.1-0.3-0.20.3-0.1-0.30.20.4-0.5-0.30.2-0.50.1-0.3
Reaction time trials completed0.20.31.6-0.40.30.4-0.80.2-0.2-0.60.4-0.10.0-0.6-1.3-0.8-0.2
Reaction time trials AUC0.30.41.7-0.50.40.6-1.10.3-0.0-0.80.3-0.00.2-0.8-1.3-1.0-0.1
Social response proportion4.04.45.61.8-2.2-2.11.7-2.0-2.21.92.4-2.3-2.22.0-1.82.2-2.3
Social responses0.20.30.80.3-0.5-0.60.6-0.3-0.30.80.4-0.4-0.40.80.30.9-0.3
Social time1.11.53.41.2-1.3-1.41.8-1.0-0.71.70.6-0.7-1.01.60.71.6-0.7
Conditioned locomotion0.40.43.00.0-0.2-0.0-0.6-0.3-0.7-0.40.9-0.6-0.4-0.2-1.7-0.3-0.7
Cocaine response after cond. corrected0.30.30.90.4-0.5-0.40.3-0.5-0.80.20.7-0.6-0.60.2-1.00.2-0.7
Cocaine response after cond. not corrected0.50.52.50.3-0.5-0.40.1-0.6-1.00.21.0-0.8-0.70.0-1.60.1-0.9
Cocaine response before conditioning1.21.44.20.8-1.0-0.90.4-1.1-1.40.81.7-1.5-1.30.4-2.10.6-1.5
Saline control response0.30.40.60.7-0.7-0.60.7-0.7-0.80.50.7-0.6-0.70.5-0.70.5-0.7
Condit. Reinf. active minus inactive responses3.94.85.62.2-2.3-2.21.9-2.2-2.32.22.4-2.4-2.32.1-1.82.0-2.4
Condit. Reinf. active-inactive response ratio2.02.15.61.2-1.3-1.10.8-1.4-1.70.81.8-1.7-1.60.7-2.40.7-1.8
Condit. Reinf. active responses4.76.57.42.6-2.7-2.72.4-2.6-2.52.72.6-2.7-2.72.6-1.72.5-2.7
Condit. Reinf. inactive responses2.22.74.31.7-1.7-1.81.9-1.6-1.22.01.3-1.5-1.52.10.12.1-1.4
Condit. Reinf. lever presses7.810.813.93.5-3.5-3.63.7-3.3-2.93.62.9-3.2-3.33.7-1.13.6-3.1
Condit. Reinf. lever reinforcers received5.47.68.72.8-2.9-2.82.5-2.8-2.82.72.9-3.0-2.92.7-2.02.6-2.9
Pavlov. Cond. lever latency3.95.37.3-2.42.52.5-2.62.32.0-2.7-2.02.22.3-2.60.6-2.62.1
Pavlov. Cond. magazine entry latency2.42.74.21.8-1.8-1.81.9-1.7-1.32.11.3-1.4-1.62.0-0.11.9-1.4
Pavlov. Cond. change in total contacts7.410.313.93.3-3.4-3.53.6-3.2-2.83.72.8-3.1-3.23.6-0.93.7-3.0
Pavlov. Cond. index score3.84.97.42.4-2.4-2.52.7-2.2-1.82.71.8-2.0-2.12.6-0.22.6-1.9
Pavlov. Cond. latency score3.64.56.92.3-2.3-2.42.5-2.1-1.72.61.7-1.9-2.12.5-0.22.5-1.9
Pavlov. Cond. lever contacts3.65.17.02.4-2.4-2.52.6-2.2-1.92.61.9-2.1-2.22.6-0.52.5-2.1
Pavlov. Cond. magazine entry number2.12.64.9-1.81.71.8-2.21.51.0-2.2-1.01.21.4-2.0-0.6-2.01.1
Pavlov. Cond. intertrial magazine entries1.41.93.3-1.51.51.5-1.61.41.0-1.7-0.91.01.2-1.8-0.3-1.81.1
Pavlov. Cond. lever-magazine prob. diff.4.05.27.22.5-2.4-2.52.6-2.3-1.92.71.9-2.1-2.22.6-0.42.5-2.1
Pavlov. Cond. response bias4.15.67.92.5-2.5-2.62.8-2.4-2.02.82.1-2.3-2.42.7-0.62.6-2.2
Conditioned reinforcement - actives0.20.20.80.4-0.3-0.2-0.1-0.6-0.5-0.10.5-0.4-0.40.1-0.90.1-0.5
Conditioned reinforcement - inactives1.82.02.51.5-1.5-1.41.4-1.6-1.61.11.5-1.5-1.51.3-1.31.3-1.5
Conditioned locomotion1.61.93.5-1.41.51.6-1.91.21.3-1.6-1.11.21.4-1.60.2-1.61.2
Intermittent access intake day 1-15 change1.61.62.41.5-1.3-1.31.3-1.6-1.21.21.1-1.1-1.21.4-0.51.4-1.2
Intermittent access intake escalation1.21.21.91.3-1.2-1.21.1-1.3-1.01.20.9-0.9-1.11.4-0.21.4-0.9
Intermittent access intake escalation 22.92.93.51.8-1.8-1.71.7-1.9-1.81.51.7-1.7-1.81.5-1.31.6-1.7
Intermitt. access day 1 inactive lever presses1.21.33.71.2-1.0-1.21.3-1.1-0.71.90.6-0.7-0.81.40.81.4-0.6
Intermitt. access day 15 inactive lever presses0.50.51.10.8-0.7-0.81.0-0.8-0.31.00.3-0.4-0.61.00.51.0-0.5
Intermitt. access escalation Index0.10.00.2-0.0-0.2-0.20.30.1-0.3-0.10.2-0.3-0.30.2-0.4-0.0-0.1
Intermittent access day 1 total infusions0.60.71.7-0.70.60.8-1.00.70.0-1.3-0.10.20.4-1.1-1.2-1.20.3
Intermittent access day 15 total infusions0.50.61.10.8-0.8-0.70.4-0.9-1.00.20.9-0.9-0.80.6-1.10.5-0.8
Intermittent access terminal intake (last 3 days)1.01.02.61.0-1.0-0.80.7-1.1-1.30.21.2-1.2-1.10.7-1.60.5-1.1
Intermittent access total infusions0.30.31.70.5-0.4-0.30.0-0.5-0.7-0.30.7-0.6-0.50.0-1.3-0.1-0.6
Intermittent access day 1 locomotion0.30.30.9-0.50.50.6-0.90.4-0.0-0.80.10.10.3-0.9-0.9-0.90.1
Intermittent access day 15 total locomotion0.00.00.1-0.20.20.2-0.30.00.1-0.4-0.10.20.2-0.2-0.0-0.20.2
Intermittent access total locomotion0.60.71.5-0.80.91.0-1.20.60.6-1.1-0.60.70.8-1.1-0.1-1.00.7
Intermittent access standard deviation5.76.07.92.8-2.6-2.72.7-2.6-2.32.62.1-2.3-2.52.7-0.82.7-2.2
Cocaine induced anxiety0.20.20.70.2-0.3-0.40.5-0.20.30.8-0.0-0.2-0.10.60.80.6-0.2
Post-drug Anxiety0.30.42.3-0.30.20.10.10.21.00.2-0.80.50.50.31.50.20.4
Baseline Anxiety0.50.51.3-0.60.70.8-0.90.60.2-1.1-0.20.40.5-1.0-0.7-1.10.4
Lifetime Intake0.20.20.8-0.10.20.3-0.60.1-0.2-0.70.2-0.10.0-0.5-0.9-0.5-0.0
Incentive Sensitization - Responses0.10.10.30.3-0.1-0.20.5-0.30.00.2-0.10.0-0.10.30.40.2-0.0
Incentive Sensitization - Breakpoint0.10.10.40.10.0-0.00.4-0.20.20.1-0.30.20.10.20.60.10.2
Progressive ratio test 1 active lever presses1.11.12.60.8-1.0-0.90.5-0.8-1.40.61.4-1.3-1.20.7-1.60.6-1.1
Progressive ratio test 1 breakpoint1.51.62.91.0-1.2-1.20.8-1.0-1.60.91.6-1.5-1.40.9-1.70.8-1.3
Progressive ratio test 1 inactive lever presses0.60.61.00.9-0.8-0.80.9-0.9-0.70.90.4-0.5-0.61.00.31.0-0.6
Progressive ratio test 2 active lever presses0.50.50.60.8-0.7-0.70.7-0.8-0.80.40.7-0.8-0.80.7-0.60.6-0.7
Progressive ratio test 2 breakpoint0.40.50.70.7-0.7-0.60.7-0.8-0.80.40.7-0.8-0.80.5-0.80.4-0.7
Progressive ratio test 2 inactive lever presses3.23.75.22.2-2.1-2.12.3-2.1-1.72.01.5-1.8-1.92.2-0.52.1-1.7
Total sessions with >9 infusions1.01.12.5-1.00.81.0-1.60.7-0.0-1.40.10.20.5-1.5-1.6-1.60.4
Short access day 1 total inactive lever presses0.70.81.41.1-1.0-1.01.1-1.0-0.60.90.4-0.7-0.81.20.31.2-0.7
Short access day 10 total inactive lever presses1.11.22.91.1-1.0-1.11.4-1.0-0.31.70.3-0.5-0.71.41.11.6-0.6
Short access day 1 total infusions0.20.21.50.1-0.2-0.1-0.3-0.1-0.8-0.30.7-0.5-0.4-0.1-1.2-0.1-0.4
Short access day 10 total infusions0.40.51.3-0.60.70.8-1.00.60.4-0.9-0.20.30.5-1.0-0.6-1.10.4
Short access total infusions0.70.81.9-0.80.91.0-1.30.80.3-1.2-0.20.40.6-1.3-0.9-1.40.5
Short access day 1 locomotion1.92.04.2-1.51.61.7-2.11.31.0-1.5-0.91.31.4-1.8-0.1-1.81.1
Short access day 10 total locomotion0.30.30.70.7-0.4-0.40.2-0.8-0.60.80.8-0.6-0.60.2-0.70.4-0.6
Short access total locomotion0.80.82.0-0.70.91.0-1.40.40.3-1.1-0.20.50.6-1.4-0.9-1.30.3
Compulsive drug intake0.40.41.10.7-0.7-0.70.8-0.6-0.50.40.4-0.4-0.60.80.01.0-0.6
One hour access (0.3 mA shock)1.41.62.31.5-1.3-1.41.4-1.5-1.11.21.0-1.2-1.21.4-0.41.4-1.2
One hour access (shock baseline)0.10.10.20.4-0.4-0.40.3-0.5-0.40.30.4-0.4-0.40.5-0.30.3-0.3
Number of responses in last shaping day1.71.83.11.1-1.4-1.31.0-1.2-1.70.71.6-1.5-1.50.9-1.81.0-1.4
Context. condit. distance diff. score0.10.10.2-0.40.20.2-0.10.40.3-0.1-0.30.20.3-0.00.4-0.10.3
Locomotion velocity, session 12.02.13.0-1.41.51.4-1.01.61.7-1.1-1.71.51.6-1.11.7-1.21.7
Locomotion distance, session 10.71.01.31.2-1.0-1.01.2-1.1-1.00.80.9-1.1-1.00.7-0.80.7-1.0
Locomotion velocity, session 20.40.40.9-0.80.70.7-0.90.70.6-0.6-0.60.70.7-0.50.5-0.50.7
Locomotion distance, session 20.81.22.5-1.01.21.2-1.20.90.6-1.4-0.70.80.9-1.6-0.4-1.60.8
Locomotion velocity, session 30.30.30.9-0.70.60.7-0.90.70.4-0.8-0.30.40.5-0.7-0.2-0.60.4
Locomotion distance, session 35.25.67.22.4-2.4-2.31.9-2.5-2.72.12.7-2.5-2.52.0-2.32.1-2.6
Stereotopy head waving bouts, day 30.91.12.8-1.41.01.1-1.71.20.8-1.3-0.50.50.9-1.1-0.3-1.10.7
Stereotopy head waving duration, day 32.63.14.6-2.11.81.8-2.12.01.7-1.8-1.61.61.8-1.51.1-1.51.8
Locomotion velocity, session 70.00.00.10.0-0.1-0.2-0.0-0.1-0.20.20.1-0.0-0.10.30.20.4-0.0
Locomotion distance, session 70.10.10.20.2-0.2-0.20.2-0.3-0.40.20.3-0.3-0.30.2-0.30.2-0.3
Stereotopy head waving bouts, day 70.20.20.6-0.50.40.5-0.70.40.0-0.8-0.10.30.3-0.5-0.5-0.50.2
Stereotopy head waving duration, day 71.21.52.3-1.31.31.3-1.41.20.9-1.5-1.01.21.2-1.30.2-1.31.1
Locomotion velocity, session 83.74.45.7-2.42.22.3-2.32.32.0-2.4-1.91.82.1-2.30.7-2.32.0
Locomotion distance, session 80.40.60.9-0.80.80.8-0.60.80.6-0.9-0.70.60.8-0.90.2-1.00.7
Degree of sensitization distance2.72.74.5-1.71.61.5-1.21.82.0-1.2-1.91.81.8-1.02.1-1.11.9
Degree of sensitization stereotypy0.20.20.7-0.30.30.4-0.50.2-0.1-0.8-0.00.20.2-0.6-0.8-0.60.0
Condit. Reinf. active minus inactive responses0.30.30.5-0.50.60.5-0.50.60.7-0.4-0.50.40.6-0.60.4-0.50.5
Condit. Reinf. active-inactive response ratio0.20.20.4-0.50.40.4-0.50.60.6-0.3-0.40.30.5-0.40.4-0.30.4
Condit. Reinf. active responses1.41.73.1-1.21.41.5-1.41.21.1-1.4-1.11.21.3-1.80.1-1.71.2
Condit. Reinf. inactive responses1.11.32.9-0.91.21.3-1.10.80.7-1.3-0.91.11.0-1.6-0.2-1.71.0
Incentive salience index mean0.10.10.3-0.20.30.3-0.30.20.1-0.2-0.10.10.2-0.6-0.3-0.50.1
Condit. Reinf. lever presses0.10.10.30.4-0.2-0.20.3-0.4-0.50.40.4-0.4-0.4-0.0-0.6-0.0-0.4
Time in familiar zone, hab. session 10.30.30.50.6-0.5-0.60.7-0.6-0.70.60.5-0.5-0.50.5-0.20.5-0.5
Time in novel zone, hab. session 10.20.20.6-0.60.50.5-0.50.50.3-0.8-0.40.40.4-0.5-0.1-0.50.3
Total zone transitions, hab. session 10.40.61.20.9-0.6-0.60.8-0.9-1.00.40.8-0.8-0.80.2-1.10.3-0.8
Total locomotion distance, hab. session 13.04.36.12.4-2.1-2.12.5-2.3-2.12.01.9-2.0-2.11.9-1.22.0-2.1
Locomotion velocity, hab. session 11.42.03.31.7-1.4-1.51.8-1.6-1.31.51.2-1.4-1.41.3-0.71.3-1.3
Time in familiar zone, hab. session 21.21.22.81.0-1.1-1.21.3-0.9-0.61.50.6-0.8-0.81.60.81.7-0.6
Time in novel zone, hab. session 20.90.91.6-0.91.01.1-1.00.90.7-1.2-0.80.90.9-1.3-0.1-1.30.8
Total zone transitions, hab. session 20.70.92.4-0.70.81.0-1.10.50.1-1.4-0.20.30.5-1.5-1.4-1.50.2
Total locomotion distance, hab. session 20.30.41.10.6-0.5-0.40.4-0.6-0.70.10.7-0.7-0.60.2-1.00.2-0.8
Locomotion velocity, hab. session 20.20.31.60.4-0.3-0.20.1-0.5-0.6-0.10.7-0.7-0.5-0.1-1.3-0.1-0.7
Novel to familiar place preference ratio0.90.91.41.1-1.0-0.90.8-1.2-1.20.61.0-0.9-1.10.6-1.20.6-1.1
Novelty place preference0.80.81.41.1-0.9-0.80.7-1.1-1.10.51.0-0.8-1.00.5-1.20.5-1.0
Time in novel zone, NPP test0.40.51.00.8-0.6-0.60.5-0.9-0.90.30.7-0.6-0.70.3-1.00.3-0.8
Total zone transitions, NPP test0.10.20.3-0.20.50.5-0.20.30.3-0.5-0.50.50.4-0.60.3-0.50.5
Total locomotion distance, NPP test2.02.84.01.9-1.8-1.82.0-1.7-1.41.81.4-1.6-1.61.9-0.41.9-1.5
Locomotion velocity, NPP test2.43.44.62.1-1.9-2.02.1-2.0-1.71.91.6-1.8-1.92.0-0.62.0-1.7
Pavlov. Cond. lever latency0.20.21.5-0.10.0-0.10.30.30.50.3-0.50.40.20.41.20.50.4
Pavlov. Cond. magazine entry latency0.10.20.4-0.30.40.4-0.20.40.4-0.6-0.50.40.4-0.40.3-0.40.4
Pavlov. Cond. change in total contacts0.00.00.1-0.00.10.10.00.0-0.1-0.1-0.00.00.0-0.3-0.2-0.30.0
Pavlov. Cond. index score0.10.20.8-0.20.30.4-0.50.1-0.1-0.60.1-0.00.1-0.7-0.9-0.7-0.0
Pavlov. Cond. latency score0.10.10.7-0.10.10.2-0.3-0.1-0.3-0.30.2-0.2-0.1-0.4-0.9-0.4-0.2
Pavlov. Cond. lever contacts0.50.61.60.8-0.7-0.60.4-0.9-1.00.41.0-0.9-0.80.4-1.30.3-0.9
Pavlov. Cond. magazine entry number0.10.10.50.3-0.4-0.40.3-0.3-0.30.70.3-0.3-0.30.50.10.5-0.3
Pavlov. Cond. intertrial magazine entries0.30.30.7-0.60.60.7-0.80.50.3-0.5-0.20.40.5-0.9-0.4-0.90.3
Pavlov. Cond. lever-magazine prob. diff.0.20.31.5-0.10.20.3-0.5-0.0-0.4-0.60.3-0.2-0.1-0.7-1.2-0.7-0.2
Pavlov. Cond. response bias0.10.10.40.2-0.1-0.00.1-0.2-0.3-0.20.2-0.3-0.2-0.1-0.6-0.2-0.3
Bone: apparent density0.00.10.2-0.30.30.2-0.40.20.20.0-0.20.30.3-0.20.4-0.10.4
Bone surface0.30.50.80.7-0.7-0.70.5-0.7-0.80.90.8-0.7-0.70.7-0.20.8-0.6
Bone volume0.30.40.70.7-0.7-0.70.5-0.7-0.80.80.7-0.7-0.70.7-0.30.7-0.6
Bone: connectivity density0.40.61.4-0.70.70.6-0.60.80.8-0.3-0.80.90.8-0.41.2-0.30.9
Bone: cortical apparent density2.43.14.1-1.81.91.9-1.71.81.7-1.8-1.61.61.8-1.90.8-2.01.8
Bone: cortical area1.92.93.91.7-1.7-1.71.4-1.8-1.91.41.9-2.0-1.81.5-1.61.5-1.9
Bone: cortical porosity1.51.63.4-1.41.31.4-1.81.20.7-1.6-0.60.91.1-1.6-0.6-1.70.8
Bone: cortical porosity1.71.83.8-1.51.41.5-1.91.20.7-1.8-0.70.91.1-1.8-0.7-1.80.9
Bone: cortical thickness0.71.21.91.1-1.1-1.00.7-1.1-1.30.71.3-1.4-1.20.9-1.30.8-1.3
Bone: cortical thickness0.50.51.4-0.70.70.8-1.20.60.2-1.0-0.10.20.5-1.0-0.9-1.10.2
Bone: cortical tissue density2.83.64.7-1.92.02.0-1.92.01.9-2.0-1.81.81.9-2.10.9-2.21.9
Bone: elastic displacement0.00.00.1-0.10.10.1-0.10.20.2-0.2-0.30.30.2-0.00.4-0.10.2
Bone: elastic work2.02.63.31.6-1.6-1.61.3-1.7-1.71.41.8-1.8-1.71.5-1.41.4-1.7
Bone: endosteal estimation1.32.93.71.8-1.8-1.81.8-1.8-1.61.91.6-1.6-1.71.8-0.71.8-1.6
Bone: endosteal perimeter1.42.94.21.9-1.8-1.92.0-1.8-1.52.11.4-1.5-1.62.0-0.22.0-1.5
Bone: final force1.52.53.51.6-1.6-1.61.3-1.7-1.61.41.8-1.9-1.71.4-1.51.4-1.7
Bone: final moment2.23.75.11.9-1.9-1.91.5-2.0-2.01.72.2-2.3-2.11.6-1.81.6-2.1
Bone: marrow area1.43.03.71.8-1.8-1.81.8-1.8-1.71.91.6-1.7-1.81.8-0.71.8-1.7
Bone: maximum diameter1.42.53.01.6-1.6-1.61.4-1.7-1.71.51.7-1.7-1.71.5-1.21.6-1.7
Bone: maximum force2.74.76.02.2-2.2-2.22.0-2.3-2.22.12.3-2.4-2.31.9-1.72.0-2.3
Bone: maximum moment3.56.17.72.6-2.5-2.52.2-2.6-2.62.32.6-2.8-2.62.2-2.02.2-2.6
Bone: minimum diameter5.39.911.63.2-3.3-3.22.9-3.3-3.33.03.3-3.4-3.33.0-2.42.9-3.3
Bone: periosteal estimation2.14.34.92.2-2.2-2.11.9-2.2-2.22.12.1-2.2-2.22.0-1.42.1-2.1
Bone: periosteal perimeter2.03.33.81.9-1.9-1.91.9-1.9-1.81.91.7-1.8-1.91.9-0.82.0-1.8
Bone: post-yield work1.11.52.41.4-1.3-1.41.6-1.2-0.91.50.9-1.1-1.11.50.11.6-1.0
Bone: stiffness1.42.33.01.5-1.5-1.51.4-1.5-1.51.51.5-1.7-1.61.4-1.01.5-1.5
Bone: tissue strength4.24.14.62.1-2.1-2.12.1-2.1-2.11.92.0-2.1-2.12.0-1.41.9-2.1
Bone: trabecular number0.10.20.60.4-0.4-0.50.3-0.5-0.40.80.5-0.4-0.40.50.10.6-0.3
Bone: trabecular spacing1.51.92.41.4-1.5-1.41.4-1.5-1.51.21.4-1.4-1.51.3-1.21.2-1.6
Bone: trabecular thickness0.30.40.9-0.70.70.7-0.90.60.3-0.7-0.30.40.6-0.9-0.2-0.80.5
Bone: trabecular tissue density2.53.53.9-2.02.02.0-1.92.01.8-2.0-1.91.92.0-1.91.1-1.92.0
Breakpoint value in progressive ratio session2.73.15.81.6-1.9-2.02.3-1.4-1.22.11.1-1.5-1.62.40.52.4-1.3
Distance traveled before self-admin1.51.62.31.2-1.3-1.21.1-1.2-1.40.91.5-1.4-1.40.9-1.50.9-1.5
Distance traveled after self-admin5.35.97.32.7-2.6-2.62.5-2.7-2.32.42.4-2.3-2.62.4-1.52.3-2.5
Delta time in closed arm before/after self-admin0.80.81.71.0-0.9-0.90.9-1.1-0.71.30.7-0.7-0.81.1-0.00.9-0.7
Delta time in open arm before/after self-admin0.40.41.0-0.50.50.6-0.70.6-0.0-1.0-0.10.20.3-1.0-0.9-1.00.2
Diff in mean of infusions in LGA sessions0.20.20.70.3-0.5-0.50.9-0.2-0.10.50.2-0.4-0.40.60.20.6-0.3
Extinction: sum of active levers before priming1.61.63.01.4-1.2-1.31.3-1.3-1.21.71.2-1.3-1.21.2-0.41.3-1.1
Active lever presses in extinction session 61.21.22.71.0-1.0-1.21.1-1.0-0.51.60.6-0.8-0.81.50.81.6-0.6
Delta distance traveled before/after self-admin1.61.73.51.3-1.3-1.41.6-1.2-0.71.70.6-0.8-1.01.90.81.8-0.8
Delta ambulatory time before/after self-admin1.61.82.71.4-1.4-1.51.5-1.4-1.11.61.1-1.2-1.31.6-0.11.6-1.2
Time in closed arm before self-admin0.30.41.3-0.80.40.5-0.30.80.4-1.2-0.40.30.4-0.6-0.3-0.70.3
Time in closed arm after self-admin0.40.41.00.4-0.6-0.71.0-0.3-0.10.80.2-0.4-0.50.90.50.8-0.4
Time in open arm before self-admin1.61.73.01.3-1.3-1.31.1-1.5-1.21.71.4-1.4-1.31.2-0.71.2-1.2
Time in open arm after self-admin0.80.93.80.7-0.6-0.5-0.0-0.8-1.40.41.3-1.1-0.90.0-2.0-0.1-1.0
Sum of active levers in priming session hrs 5-60.00.00.2-0.0-0.1-0.20.0-0.0-0.00.30.3-0.5-0.20.1-0.20.1-0.2
Time to tail flick, vehicle, before self-admin0.50.52.8-0.20.40.5-1.0-0.1-0.4-0.80.5-0.20.0-0.9-1.7-1.0-0.3
Time to tail flick, vehicle, after self-admin0.40.41.00.6-0.7-0.71.0-0.4-0.40.70.3-0.3-0.50.90.30.8-0.3
Time to tail flick, test, before self-admin0.30.31.2-0.40.30.4-0.80.1-0.2-0.90.2-0.00.1-0.4-1.1-0.6-0.2
Time to tail flick, test, after self-admin0.10.10.4-0.30.20.3-0.60.00.0-0.60.1-0.10.1-0.4-0.7-0.4-0.1
Delta time to tail flick, vehicle, before/after SA0.40.41.10.5-0.7-0.71.0-0.3-0.20.80.2-0.3-0.51.00.60.9-0.2
Delta time to tail flick, test, before/after SA0.10.10.2-0.20.20.3-0.30.10.1-0.4-0.00.00.1-0.4-0.3-0.40.1
Ambulatory time before self-admin0.90.91.20.9-1.0-0.91.0-0.9-1.00.71.0-1.0-1.10.7-1.00.7-1.1
Ambulatory time after self-admin6.26.98.82.8-2.8-2.83.0-2.7-2.42.92.4-2.5-2.72.8-1.22.6-2.6
Total heroin consumption1.51.82.41.4-1.3-1.31.5-1.4-1.41.21.4-1.6-1.41.1-1.11.0-1.4
Area under the delay curve0.70.72.20.7-0.7-0.81.3-0.50.11.1-0.2-0.2-0.31.31.51.1-0.2
Delay disc. indifference point, 0s delay0.80.91.71.0-1.0-1.01.3-1.0-0.61.10.4-0.7-0.81.20.41.2-0.7
Delay disc. indifference point, 16s delay2.22.24.11.6-1.6-1.72.0-1.5-0.91.90.8-1.1-1.32.00.61.8-1.2
Delay disc. indifference point, 2s delay0.91.04.20.7-0.7-0.91.5-0.40.31.1-0.4-0.0-0.21.52.01.40.1
Delay disc. indifference point, 24s delay1.91.83.11.5-1.4-1.51.7-1.4-1.11.81.0-1.1-1.31.60.01.6-1.2
Delay disc. indifference point, 4s delay0.10.20.50.4-0.4-0.40.7-0.4-0.20.40.0-0.2-0.30.50.40.5-0.2
Delay disc. indifference point, 8s delay0.70.74.2-0.50.40.20.20.71.10.3-1.10.80.70.22.10.00.9
Delay discount exponential model param0.70.71.9-0.70.70.9-1.30.5-0.0-1.10.20.20.4-1.2-1.4-1.10.2
Delay discount hyperbolic model param0.60.62.3-0.60.60.8-1.30.4-0.1-1.00.30.10.2-1.1-1.5-1.00.1
Fecal boli incidents, locomotor time 12.62.84.9-1.61.61.5-1.11.71.9-1.2-2.01.91.8-1.12.2-1.22.0
Change in fecal boli incidents, locomotor task0.10.10.30.2-0.3-0.30.1-0.3-0.40.40.5-0.4-0.40.2-0.60.3-0.5
Time >=10cm from walls, locomotor time 10.00.00.1-0.20.10.1-0.10.20.1-0.0-0.10.20.1-0.10.1-0.30.1
Bouts of movement, locomotor time 11.31.53.71.1-1.2-1.41.9-0.9-0.41.30.1-0.4-0.81.91.51.9-0.6
Total resting periods, locomotor time 11.31.43.61.1-1.2-1.31.8-0.8-0.31.30.0-0.3-0.71.91.61.9-0.4
Rest time, locomotor task time 10.10.10.1-0.20.20.2-0.20.20.2-0.3-0.30.40.3-0.20.3-0.10.3
Distance moved, locomotor task time 10.10.21.2-0.0-0.00.1-0.4-0.2-0.4-0.30.5-0.3-0.2-0.3-1.1-0.3-0.3
Vertical activity count, locomotor time 11.01.01.60.9-1.0-0.90.6-1.1-1.20.91.2-1.1-1.10.8-1.20.8-1.1
Time >=10cm from walls, locomotor time 20.10.10.7-0.10.10.2-0.3-0.0-0.1-0.60.10.00.0-0.5-0.8-0.7-0.2
Bouts of movement, locomotor time 20.40.53.20.0-0.1-0.20.50.10.70.3-0.80.30.30.81.80.80.3
Total resting periods, locomotor time 20.30.32.4-0.10.0-0.10.30.20.70.1-0.70.40.40.61.50.60.3
Rest time, locomotor task time 20.20.21.00.3-0.3-0.20.1-0.3-0.6-0.10.5-0.4-0.40.0-1.0-0.1-0.5
Distance moved, locomotor task time 20.20.20.5-0.40.40.5-0.60.20.2-0.7-0.20.30.3-0.6-0.4-0.50.2
Vertical activity count, locomotor time 20.20.30.50.6-0.5-0.60.6-0.6-0.40.70.3-0.3-0.40.70.20.7-0.3
Weight adjusted by age0.20.20.5-0.50.50.5-0.70.50.2-0.5-0.30.30.5-0.60.0-0.50.4
Seeking ratio, delayed vs. immediate footshock1.41.62.11.3-1.4-1.41.3-1.1-1.31.31.2-1.3-1.31.4-0.61.3-1.1
Locomotion in novel chamber0.20.31.1-0.40.50.4-0.10.50.6-0.1-0.70.70.6-0.21.0-0.20.8
Locomotion in novel chamber post-restriction0.30.41.00.5-0.5-0.70.8-0.2-0.10.80.1-0.3-0.31.00.91.0-0.0
Progressive ratio0.30.31.5-0.10.50.3-0.10.20.60.0-0.70.70.6-0.11.2-0.20.7
Food seeking constrained by brief footshock3.23.94.72.2-2.1-2.12.1-2.0-1.82.21.9-2.0-2.12.0-1.02.0-1.9
Seeking ratio, punishment vs. effort1.51.92.61.2-1.5-1.41.3-1.1-1.41.01.6-1.6-1.51.2-1.41.3-1.5
Run reversals in cocaine runway, females0.20.20.8-0.30.40.3-0.20.40.6-0.1-0.60.50.5-0.10.9-0.10.6
Run reversals in cocaine runway, males1.21.22.1-1.41.11.2-1.41.50.9-0.9-0.70.81.0-1.20.1-1.21.1
Latency to leave start box in cocaine runway0.00.00.1-0.20.20.2-0.30.00.2-0.2-0.20.20.2-0.00.2-0.20.1
Latency to leave start box in cocaine runway, F0.40.40.7-0.80.70.6-0.80.70.7-0.7-0.60.60.7-0.40.5-0.60.6
Latency to leave start box in cocaine runway, M0.10.10.20.4-0.3-0.30.5-0.4-0.40.20.1-0.1-0.30.30.00.4-0.2
Cd content in liver0.20.30.7-0.40.50.4-0.20.60.7-0.3-0.70.50.5-0.30.9-0.30.6
Co content in liver1.61.92.5-1.51.41.4-1.31.61.5-1.0-1.41.31.5-1.31.2-1.31.5
Cu content in liver0.91.11.61.1-1.1-1.00.8-1.1-1.10.61.2-1.3-1.10.9-1.20.7-1.3
Fe content in liver0.20.31.1-0.40.40.3-0.00.50.6-0.1-0.70.60.5-0.21.0-0.20.7
K content in liver0.50.51.60.5-0.5-0.50.2-0.6-0.80.30.9-0.8-0.70.2-1.30.2-0.9
Mg content in liver0.20.21.2-0.30.20.3-0.60.1-0.2-0.60.3-0.2-0.0-0.5-1.1-0.6-0.2
Mn content in liver0.81.06.7-0.20.10.4-1.0-0.2-0.8-0.90.9-0.6-0.3-1.0-2.6-1.1-0.7
Na content in liver4.64.96.52.2-2.2-2.11.8-2.4-2.52.02.5-2.3-2.41.8-2.21.9-2.5
Rb content in liver0.00.00.00.1-0.1-0.10.1-0.10.0-0.0-0.00.1-0.00.20.10.1-0.1
Se content in liver5.36.410.8-2.72.72.9-3.12.41.8-3.2-1.82.02.3-3.2-0.3-3.32.1
Sr content in liver0.90.81.0-1.01.01.0-1.01.00.8-0.9-0.70.80.9-1.00.2-1.00.9
Zn content in liver0.30.30.4-0.60.60.6-0.60.60.6-0.5-0.60.50.6-0.60.4-0.60.6