Hub : Genes

Ovol1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000020669 0.12 0.07 2.1e-08 0.06 0.06 0.05 0.05 2.5e-07 7.2e-07 2.7e-06 1.8e-06
2 BLA gene expression ENSRNOG00000020669 0.23 0.13 6.1e-07 0.13 0.14 0.14 0.13 1.4e-07 1.1e-07 1.0e-07 1.2e-07
3 Brain gene expression ENSRNOG00000020669 0.23 0.11 3.4e-12 0.1 0.14 0.13 0.12 1.2e-09 1.8e-12 1.1e-11 1.3e-11
4 IL gene expression ENSRNOG00000020669 0.25 0.13 1.1e-03 0.03 0.06 -0.01 0.03 8.1e-02 1.2e-02 4.7e-01 6.0e-02
5 LHb gene expression ENSRNOG00000020669 0.21 0.11 7.2e-04 0.02 0.1 0.07 0.06 9.0e-02 2.4e-03 9.7e-03 1.6e-02
6 NAcc gene expression ENSRNOG00000020669 0.08 0.04 1.1e-05 0.01 0.05 0.01 0.04 3.9e-02 2.4e-04 2.4e-02 8.4e-04
7 OFC gene expression ENSRNOG00000020669 0.25 0.15 8.6e-03 0.16 0.07 0.08 0.11 1.0e-04 7.6e-03 5.2e-03 1.2e-03
8 PL gene expression ENSRNOG00000020669 0.34 0.11 0.0e+00 0.29 0.29 0.29 0.3 5.7e-22 5.1e-22 6.2e-22 8.9e-23

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail8.427.333.5-4.9-5.8-5.2-5.4-4.4-5.2-5.4-5.3
BMI without tail3.98.29.7-2.6-3.1-3.0-2.9-2.4-2.8-3.1-3.0
Body weight3.615.322.6-2.9-4.4-4.0-4.1-4.8-4.4-3.1-3.2
Epididymis fat weight0.71.65.30.20.61.61.22.31.70.30.4
Glucose0.30.51.5-0.7-0.50.3-0.01.20.4-0.8-0.9
Heart weight1.01.44.60.80.81.21.22.21.60.10.3
Left kidney weight0.30.81.60.10.81.01.01.31.20.50.4
Right kidney weight0.30.81.30.10.81.21.00.61.01.00.9
Tail length0.31.02.41.50.60.40.7-0.70.31.51.3
Length with tail0.41.35.80.4-0.9-0.9-0.8-2.4-1.30.60.3
Length without tail0.81.85.5-0.4-1.5-1.2-1.3-2.3-1.7-0.2-0.5
Liver weight, left0.00.00.10.0-0.30.20.10.20.2-0.0-0.1
Liver weight, right0.10.20.70.7-0.90.30.30.20.30.3-0.1
Parametrial fat weight0.30.72.2-0.9-0.30.30.11.50.6-1.0-0.9
Retroperitoneal fat weight1.65.216.00.81.62.72.34.03.00.80.8
Intraocular pressure2.13.04.21.01.82.01.81.51.81.81.9
Extensor digitorum longus weight5.019.937.6-3.1-4.5-4.9-4.7-6.1-5.2-3.1-3.2
Soleus weight1.85.312.21.41.72.52.63.53.11.21.2
Tibialis anterior weight3.712.737.6-1.7-3.7-3.6-3.6-6.1-4.4-1.1-1.5
Tibia length0.20.72.5-0.9-0.4-0.1-0.6-1.6-0.80.80.5
Number of licking bursts0.20.20.4-0.6-0.2-0.5-0.5-0.6-0.6-0.3-0.2
Food consumed during 24 hour testing period0.50.61.20.51.00.80.60.20.51.01.1
Times rat made contact with spout0.40.51.0-0.3-0.1-1.0-0.8-0.7-0.8-0.6-0.6
Mean time between licks in bursts0.20.30.80.9-0.7-0.4-0.2-0.6-0.4-0.0-0.1
Mean num. licks in bursts0.10.10.30.40.40.10.20.50.30.1-0.0
Std. dev. time between licks in bursts0.40.52.11.5-0.10.40.70.40.60.40.4
Water consumed over 24 hours0.20.20.40.10.5-0.5-0.4-0.7-0.60.10.2
Indifference point 0 sec0.00.00.0-0.00.20.0-0.00.20.0-0.0-0.2
Indifference point AUC1.21.44.0-1.0-0.6-1.2-1.3-2.0-1.6-0.2-0.4
Indifference point function ln k3.54.911.92.11.32.22.53.42.90.90.9
Indifference point function log k3.54.911.92.11.32.22.53.42.90.90.9
Delay discounting total patch changes 0 sec0.10.10.20.50.40.20.30.20.30.30.2
Delay discounting total patch changes 12 sec2.93.87.4-1.6-1.2-2.2-2.2-2.7-2.5-1.2-1.4
Delay discounting total patch changes 18 sec0.60.81.2-1.1-0.6-0.9-1.1-1.0-1.1-0.5-0.8
Delay discounting total patch changes 24 sec0.50.72.5-0.2-0.5-0.7-0.8-1.6-1.10.1-0.1
Delay discounting total patch changes 6 sec0.81.21.9-0.6-1.0-1.2-1.2-1.4-1.4-0.8-1.0
Delay discounting time to switch 0 sec4.36.68.1-2.9-2.4-2.6-2.8-2.3-2.7-2.5-2.4
Delay discounting water rate 0 sec6.39.912.33.12.83.43.53.23.52.92.8
Delay discounting water rate 12 sec10.515.720.34.23.24.14.44.44.53.33.3
Delay discounting water rate 18 sec2.83.75.62.31.12.02.22.42.31.31.3
Delay discounting water rate 24 sec4.96.89.42.71.72.83.02.93.12.12.2
Delay discounting water rate 6 sec4.97.210.43.21.72.83.02.93.12.12.2
Locomotor activity2.53.95.82.41.42.02.32.12.21.51.7
Locomotor testing distance3.45.68.72.91.62.42.62.52.61.91.9
Locomotor testing rearing2.13.35.22.31.41.81.92.22.01.31.3
Light reinforcement 10.40.71.10.81.10.70.80.80.80.90.7
Light reinforcement 20.91.22.20.20.91.51.11.21.21.31.0
Reaction time number correct0.10.20.40.6-0.20.30.3-0.40.10.60.5
Reaction time mean minus median2.02.64.9-1.8-1.2-1.5-1.8-2.2-2.0-0.9-0.9
Reaction time mean minus median AUC0.50.72.1-0.7-0.6-0.7-0.9-1.5-1.1-0.1-0.1
Reaction time num false alarms0.30.31.21.10.20.30.70.60.70.10.2
Reaction time num false alarms AUC0.10.10.40.7-0.2-0.30.2-0.10.1-0.1-0.1
Reaction time trials correct on left0.10.20.40.6-0.20.30.3-0.40.10.60.5
Reaction time trials on left0.10.20.40.6-0.20.20.3-0.50.10.70.5
Reaction time mean0.10.10.4-0.60.5-0.1-0.2-0.2-0.2-0.10.1
Reaction time mean AUC0.10.10.7-0.80.4-0.2-0.3-0.2-0.3-0.3-0.1
Median of all reaction times0.10.10.4-0.50.60.1-0.00.20.1-0.10.0
Reaction time omissions0.70.92.1-0.8-0.5-1.2-1.0-1.4-1.2-0.6-0.6
Reaction time false alarm rate0.10.10.30.50.0-0.10.30.40.4-0.2-0.1
Reaction time premature initiation rate0.60.92.50.5-1.0-1.1-0.7-1.6-1.1-0.3-0.3
Reaction time premature initiations0.71.03.90.7-1.0-1.0-0.7-2.0-1.10.10.0
Std. dev. reaction times0.40.51.1-1.0-0.2-0.7-0.8-1.1-0.9-0.3-0.2
Reaction time trials completed0.10.20.40.6-0.20.20.3-0.50.10.70.5
Reaction time trials AUC0.10.20.40.7-0.30.30.3-0.30.10.60.5
Social response proportion0.50.51.0-0.7-0.6-0.6-0.8-1.0-1.0-0.4-0.3
Social responses0.10.10.30.5-0.00.20.1-0.3-0.10.40.4
Social time0.10.10.30.5-0.10.10.1-0.4-0.10.40.4
Conditioned locomotion0.60.72.0-0.2-1.1-0.9-0.7-1.4-0.9-0.4-0.5
Cocaine response after cond. corrected0.60.71.61.00.10.80.91.31.10.10.2
Cocaine response after cond. not corrected0.40.51.20.9-0.10.70.81.10.90.00.1
Cocaine response before conditioning0.30.40.8-0.7-0.3-0.5-0.7-0.9-0.8-0.3-0.2
Saline control response2.02.75.7-0.6-1.8-1.7-1.7-2.4-2.1-0.8-1.0
Condit. Reinf. active minus inactive responses0.00.10.3-0.50.10.2-0.10.3-0.0-0.00.1
Condit. Reinf. active-inactive response ratio0.20.20.7-0.8-0.20.50.10.50.3-0.00.0
Condit. Reinf. active responses0.20.30.7-0.8-0.1-0.6-0.8-0.3-0.7-0.5-0.5
Condit. Reinf. inactive responses0.60.71.4-0.4-0.2-1.2-1.1-0.7-1.1-0.9-0.9
Condit. Reinf. lever presses1.21.73.5-1.3-1.0-1.2-1.6-1.9-1.7-0.6-0.6
Condit. Reinf. lever reinforcers received0.30.40.8-0.9-0.0-0.7-0.9-0.6-0.9-0.4-0.4
Pavlov. Cond. lever latency0.30.50.90.70.80.50.80.90.80.30.3
Pavlov. Cond. magazine entry latency3.13.65.5-1.7-1.3-2.1-2.2-2.4-2.3-1.4-1.4
Pavlov. Cond. change in total contacts1.72.44.2-2.0-0.7-1.5-1.8-1.9-1.9-1.1-0.9
Pavlov. Cond. index score2.02.64.3-1.7-1.2-1.6-1.8-2.1-2.0-1.1-1.1
Pavlov. Cond. latency score1.82.33.6-1.6-1.2-1.5-1.7-1.9-1.8-1.0-1.0
Pavlov. Cond. lever contacts0.10.10.5-0.1-0.20.0-0.3-0.7-0.40.40.3
Pavlov. Cond. magazine entry number4.55.59.72.21.52.62.73.12.91.51.6
Pavlov. Cond. intertrial magazine entries0.70.91.80.60.51.21.11.31.20.70.7
Pavlov. Cond. lever-magazine prob. diff.2.33.05.0-1.8-1.3-1.8-2.0-2.2-2.1-1.1-1.2
Pavlov. Cond. response bias0.81.12.7-1.0-0.7-1.0-1.3-1.6-1.4-0.4-0.5
Conditioned reinforcement - actives0.60.61.20.40.61.10.70.60.81.00.9
Conditioned reinforcement - inactives4.85.49.01.22.72.72.43.02.61.61.9
Conditioned locomotion7.69.113.32.23.03.43.23.63.52.62.4
Intermittent access intake day 1-15 change2.02.02.71.01.41.61.51.11.41.61.5
Intermittent access intake escalation1.21.11.60.71.21.31.11.01.11.11.0
Intermittent access intake escalation 21.21.21.60.81.31.21.10.71.11.21.2
Intermitt. access day 1 inactive lever presses1.21.32.80.51.41.21.11.71.30.50.7
Intermitt. access day 15 inactive lever presses1.61.83.10.51.51.61.31.81.50.91.1
Intermitt. access escalation Index0.50.42.20.00.40.30.41.50.7-0.4-0.4
Intermittent access day 1 total infusions0.70.83.8-0.8-0.10.70.21.90.8-0.6-0.7
Intermittent access day 15 total infusions3.13.59.00.61.52.31.83.02.31.21.0
Intermittent access terminal intake (last 3 days)1.71.85.40.10.81.81.22.31.60.70.6
Intermittent access total infusions0.70.83.6-0.50.31.10.51.91.0-0.0-0.1
Intermittent access day 1 locomotion0.60.61.9-0.8-0.60.1-0.21.40.3-1.0-1.0
Intermittent access day 15 total locomotion1.71.85.10.21.31.61.22.31.60.70.6
Intermittent access total locomotion0.91.04.7-0.80.31.00.52.21.1-0.3-0.4
Intermittent access standard deviation1.61.82.40.91.31.51.31.41.41.21.3
Cocaine induced anxiety0.10.10.20.1-0.00.40.30.10.20.40.3
Post-drug Anxiety0.20.21.00.0-0.70.1-0.2-1.0-0.40.40.2
Baseline Anxiety0.70.72.4-0.2-0.9-0.8-0.7-1.6-1.0-0.2-0.2
Lifetime Intake0.50.62.9-0.60.10.80.31.70.8-0.3-0.3
Incentive Sensitization - Responses0.10.10.3-0.30.30.50.20.60.30.20.1
Incentive Sensitization - Breakpoint0.20.20.6-0.20.50.70.40.80.50.40.3
Progressive ratio test 1 active lever presses1.51.53.50.61.21.41.21.91.40.80.9
Progressive ratio test 1 breakpoint1.71.73.30.81.31.51.31.81.50.91.0
Progressive ratio test 1 inactive lever presses0.50.51.50.31.00.60.61.20.80.20.4
Progressive ratio test 2 active lever presses2.02.14.90.41.41.81.42.21.71.00.9
Progressive ratio test 2 breakpoint3.53.97.31.01.92.42.02.72.31.51.5
Progressive ratio test 2 inactive lever presses3.54.010.50.52.12.31.93.22.31.01.1
Total sessions with >9 infusions0.20.21.0-0.2-0.50.30.11.00.4-0.4-0.5
Short access day 1 total inactive lever presses1.01.13.80.41.01.11.02.01.40.20.4
Short access day 10 total inactive lever presses1.92.14.61.21.61.31.62.11.80.70.8
Short access day 1 total infusions0.50.51.5-0.8-0.3-0.0-0.21.20.3-0.8-0.9
Short access day 10 total infusions1.41.52.8-1.7-1.2-0.8-1.10.4-0.7-1.6-1.7
Short access total infusions0.50.51.0-0.9-0.8-0.3-0.50.7-0.1-0.9-1.0
Short access day 1 locomotion0.30.31.4-0.5-0.30.1-0.01.20.3-0.6-0.6
Short access day 10 total locomotion0.40.40.9-0.7-0.3-0.2-0.30.80.0-0.9-0.9
Short access total locomotion0.40.40.9-0.7-0.5-0.3-0.40.7-0.1-1.0-0.9
Compulsive drug intake0.50.51.80.4-0.2-1.0-0.6-1.4-0.9-0.2-0.1
One hour access (0.3 mA shock)5.76.613.81.42.33.12.63.73.11.81.8
One hour access (shock baseline)4.65.311.30.82.12.92.33.42.81.61.6
Number of responses in last shaping day1.41.42.01.21.11.21.21.41.31.01.0
Context. condit. distance diff. score0.50.72.10.50.50.70.91.51.10.20.1
Locomotion velocity, session 10.10.10.50.7-0.20.20.30.00.30.30.2
Locomotion distance, session 11.92.53.2-1.3-1.8-1.7-1.6-1.2-1.6-1.6-1.8
Locomotion velocity, session 23.23.85.0-1.5-2.1-2.1-2.0-2.2-2.1-1.7-1.7
Locomotion distance, session 21.72.53.2-1.2-1.6-1.8-1.6-1.4-1.6-1.6-1.7
Locomotion velocity, session 30.70.82.2-0.7-1.5-0.7-0.7-0.2-0.5-1.1-1.3
Locomotion distance, session 30.00.00.00.1-0.10.00.00.10.1-0.0-0.1
Stereotopy head waving bouts, day 30.50.62.3-0.2-1.5-0.3-0.30.3-0.1-1.0-1.2
Stereotopy head waving duration, day 30.10.20.5-0.1-0.60.20.10.70.3-0.4-0.5
Locomotion velocity, session 71.51.63.2-1.4-1.3-1.1-1.1-0.1-0.7-1.7-1.8
Locomotion distance, session 70.60.81.7-0.5-1.1-0.9-0.7-0.2-0.6-1.2-1.3
Stereotopy head waving bouts, day 70.10.20.8-0.9-0.1-0.1-0.30.2-0.2-0.5-0.4
Stereotopy head waving duration, day 71.51.92.9-1.7-1.0-1.3-1.6-1.3-1.5-1.3-1.2
Locomotion velocity, session 80.30.30.80.6-0.9-0.3-0.3-0.9-0.50.20.0
Locomotion distance, session 80.40.51.3-0.7-1.1-0.5-0.50.0-0.3-0.9-1.1
Degree of sensitization distance0.80.81.7-0.7-1.3-0.8-0.8-0.4-0.7-1.2-1.2
Degree of sensitization stereotypy0.70.71.7-1.3-0.4-0.7-1.0-0.8-1.0-0.7-0.6
Condit. Reinf. active minus inactive responses0.40.40.7-0.6-0.4-0.8-0.7-0.6-0.7-0.8-0.7
Condit. Reinf. active-inactive response ratio0.10.10.2-0.20.5-0.3-0.2-0.1-0.2-0.3-0.1
Condit. Reinf. active responses0.50.61.0-0.9-0.7-0.8-0.7-0.5-0.6-1.0-0.9
Condit. Reinf. inactive responses0.50.61.3-1.0-1.1-0.5-0.6-0.3-0.4-0.9-0.9
Incentive salience index mean1.21.52.1-1.2-1.2-1.4-1.2-1.0-1.1-1.4-1.3
Condit. Reinf. lever presses0.81.11.9-1.1-1.4-0.9-0.9-1.0-0.9-1.0-1.0
Time in familiar zone, hab. session 10.10.10.3-0.4-0.4-0.2-0.20.2-0.1-0.5-0.5
Time in novel zone, hab. session 10.90.91.91.40.70.91.00.70.90.90.9
Total zone transitions, hab. session 10.71.01.6-1.0-0.5-1.3-1.1-1.2-1.2-0.8-0.8
Total locomotion distance, hab. session 10.20.30.7-0.7-0.6-0.3-0.30.2-0.1-0.7-0.8
Locomotion velocity, hab. session 10.30.40.8-0.8-0.7-0.6-0.5-0.2-0.4-0.7-0.9
Time in familiar zone, hab. session 20.40.41.91.4-0.20.50.70.30.50.60.4
Time in novel zone, hab. session 20.60.61.5-1.2-0.1-0.8-0.9-0.4-0.8-0.9-0.7
Total zone transitions, hab. session 24.55.86.9-2.2-2.3-2.5-2.6-1.9-2.6-2.5-2.5
Total locomotion distance, hab. session 21.72.33.9-1.4-1.8-1.4-1.4-0.6-1.2-1.9-2.0
Locomotion velocity, hab. session 21.52.13.5-1.5-1.7-1.2-1.3-0.4-1.0-1.8-1.9
Novel to familiar place preference ratio1.01.12.5-1.6-0.3-0.9-1.2-1.2-1.2-0.7-0.5
Novelty place preference0.60.61.9-1.4-0.0-0.7-0.9-0.8-0.9-0.6-0.4
Time in novel zone, NPP test0.50.51.4-1.2-0.0-0.6-0.8-0.7-0.8-0.5-0.4
Total zone transitions, NPP test2.73.94.9-1.8-1.8-2.2-2.1-2.2-2.2-1.7-1.7
Total locomotion distance, NPP test0.91.32.0-1.1-1.2-1.2-1.1-0.7-0.9-1.4-1.4
Locomotion velocity, NPP test0.91.31.9-1.2-1.0-1.2-1.1-0.7-0.9-1.4-1.3
Pavlov. Cond. lever latency0.70.91.21.01.10.90.90.80.91.00.9
Pavlov. Cond. magazine entry latency1.41.82.9-1.7-0.8-1.4-1.4-0.8-1.2-1.6-1.4
Pavlov. Cond. change in total contacts0.70.72.5-1.6-0.1-0.8-0.8-0.5-0.7-1.0-0.7
Pavlov. Cond. index score0.20.30.7-0.8-0.2-0.6-0.5-0.5-0.5-0.6-0.4
Pavlov. Cond. latency score0.30.40.8-0.9-0.5-0.6-0.6-0.5-0.5-0.8-0.6
Pavlov. Cond. lever contacts0.20.30.6-0.6-0.6-0.5-0.4-0.3-0.4-0.8-0.6
Pavlov. Cond. magazine entry number0.10.10.50.7-0.30.30.30.50.40.1-0.0
Pavlov. Cond. intertrial magazine entries0.91.02.00.61.41.01.00.91.00.91.1
Pavlov. Cond. lever-magazine prob. diff.0.50.71.2-1.1-0.5-0.9-0.8-0.8-0.8-0.8-0.7
Pavlov. Cond. response bias0.10.10.3-0.60.1-0.3-0.3-0.3-0.3-0.3-0.1
Bone: apparent density2.03.34.0-1.9-1.8-1.7-2.0-1.2-1.9-1.8-1.9
Bone surface4.17.310.3-2.7-2.8-2.4-3.1-3.1-3.2-1.9-2.1
Bone volume2.54.36.2-2.5-2.0-1.8-2.4-2.0-2.3-1.7-1.8
Bone: connectivity density3.55.47.3-2.2-2.3-2.3-2.7-2.3-2.7-2.0-2.2
Bone: cortical apparent density0.10.10.4-0.20.6-0.6-0.2-0.4-0.3-0.0-0.0
Bone: cortical area0.20.41.2-0.5-0.7-0.4-0.5-1.1-0.7-0.1-0.2
Bone: cortical porosity0.60.71.1-0.9-0.6-0.8-0.9-0.5-0.8-1.0-0.8
Bone: cortical porosity0.91.01.3-0.9-0.9-1.0-1.1-1.0-1.1-1.1-0.9
Bone: cortical thickness0.40.73.40.4-0.3-0.9-0.5-1.9-0.90.30.2
Bone: cortical thickness0.20.31.21.10.3-0.10.3-0.50.00.50.5
Bone: cortical tissue density0.10.20.4-0.10.7-0.6-0.2-0.5-0.30.00.0
Bone: elastic displacement2.93.25.82.41.31.72.01.51.91.71.7
Bone: elastic work0.20.21.21.1-0.3-0.20.1-0.7-0.10.30.2
Bone: endosteal estimation0.51.02.7-1.3-1.7-0.0-0.50.6-0.1-1.2-1.3
Bone: endosteal perimeter0.40.81.9-1.4-1.30.3-0.40.80.0-0.9-1.0
Bone: final force2.03.36.0-1.4-2.1-1.7-1.9-2.5-2.1-1.2-1.3
Bone: final moment1.83.05.3-1.3-2.0-1.6-1.8-2.3-2.0-1.1-1.2
Bone: marrow area0.51.12.9-1.3-1.7-0.1-0.50.6-0.1-1.3-1.4
Bone: maximum diameter0.10.20.6-0.5-0.80.3-0.2-0.5-0.20.30.1
Bone: maximum force4.47.69.2-2.7-3.0-2.6-2.9-3.0-3.0-2.3-2.4
Bone: maximum moment3.86.78.1-2.5-2.9-2.4-2.7-2.8-2.8-2.1-2.3
Bone: minimum diameter0.91.73.2-1.8-1.3-0.7-1.00.3-0.6-1.8-1.8
Bone: periosteal estimation0.30.72.1-1.1-1.4-0.2-0.6-0.4-0.4-0.7-0.8
Bone: periosteal perimeter0.30.61.4-0.9-1.2-0.3-0.7-0.6-0.7-0.5-0.6
Bone: post-yield work8.511.620.6-4.5-3.1-3.0-3.5-2.0-3.1-3.6-3.8
Bone: stiffness3.86.07.4-2.6-2.3-2.4-2.7-2.6-2.7-2.1-2.1
Bone: tissue strength0.10.10.3-0.5-0.1-0.2-0.3-0.2-0.3-0.2-0.2
Bone: trabecular number1.42.23.5-1.9-1.3-1.3-1.8-1.2-1.7-1.3-1.4
Bone: trabecular spacing0.30.30.80.90.50.30.70.60.70.30.4
Bone: trabecular thickness0.20.20.5-0.7-0.0-0.1-0.40.4-0.2-0.6-0.6
Bone: trabecular tissue density2.63.65.91.21.82.12.12.42.41.41.4
Breakpoint value in progressive ratio session1.61.74.1-1.2-0.9-1.4-1.4-2.0-1.7-0.6-0.7
Distance traveled before self-admin0.40.40.8-0.9-0.4-0.5-0.7-0.9-0.7-0.3-0.2
Distance traveled after self-admin0.10.10.2-0.40.2-0.2-0.3-0.4-0.3-0.00.1
Delta time in closed arm before/after self-admin0.20.10.70.8-0.6-0.20.1-0.1-0.0-0.1-0.1
Delta time in open arm before/after self-admin0.20.20.7-0.40.80.40.1-0.00.10.50.5
Diff in mean of infusions in LGA sessions0.10.10.40.30.30.10.1-0.4-0.10.60.4
Extinction: sum of active levers before priming4.84.86.8-2.1-1.7-2.5-2.4-2.6-2.5-1.9-1.8
Active lever presses in extinction session 60.40.41.7-0.1-0.4-0.1-0.3-1.3-0.60.70.6
Delta distance traveled before/after self-admin0.10.10.40.60.30.30.40.30.30.40.3
Delta ambulatory time before/after self-admin0.10.10.60.80.20.20.30.20.30.30.3
Time in closed arm before self-admin0.10.10.6-0.8-0.2-0.1-0.4-0.2-0.3-0.2-0.2
Time in closed arm after self-admin0.10.10.30.0-0.6-0.3-0.2-0.1-0.1-0.4-0.4
Time in open arm before self-admin0.30.31.21.10.3-0.00.50.70.5-0.1-0.2
Time in open arm after self-admin0.70.81.60.91.30.80.90.70.80.80.9
Sum of active levers in priming session hrs 5-60.70.72.00.30.60.70.4-0.80.11.41.4
Time to tail flick, vehicle, before self-admin1.11.11.6-1.1-1.3-1.0-1.1-1.0-1.1-1.1-1.0
Time to tail flick, vehicle, after self-admin2.52.74.4-1.1-2.1-1.7-1.7-1.6-1.7-1.6-1.6
Time to tail flick, test, before self-admin0.70.71.6-0.7-1.1-0.6-0.60.3-0.3-1.3-1.3
Time to tail flick, test, after self-admin0.10.10.10.30.10.30.20.10.20.30.3
Delta time to tail flick, vehicle, before/after SA0.70.71.0-0.5-1.0-1.0-0.9-0.8-0.9-0.7-0.8
Delta time to tail flick, test, before/after SA1.31.22.81.11.20.80.8-0.40.51.71.6
Ambulatory time before self-admin0.30.30.9-0.9-0.2-0.2-0.6-0.7-0.6-0.1-0.1
Ambulatory time after self-admin0.10.10.8-0.90.2-0.1-0.30.0-0.2-0.3-0.2
Total heroin consumption3.03.67.8-1.4-1.5-2.2-2.0-2.8-2.3-1.2-1.2
Area under the delay curve0.50.51.7-0.6-0.4-0.8-0.7-0.0-0.5-1.3-0.8
Delay disc. indifference point, 0s delay0.40.41.4-0.6-0.6-0.6-0.40.4-0.2-1.2-0.9
Delay disc. indifference point, 16s delay0.20.20.6-0.80.7-0.0-0.00.70.2-0.5-0.3
Delay disc. indifference point, 2s delay0.10.10.2-0.2-0.4-0.0-0.10.2-0.0-0.4-0.2
Delay disc. indifference point, 24s delay0.10.10.50.70.40.10.40.40.4-0.10.1
Delay disc. indifference point, 4s delay0.20.31.10.0-0.4-0.5-0.30.2-0.2-1.1-0.6
Delay disc. indifference point, 8s delay0.20.20.80.0-0.3-0.5-0.40.0-0.3-0.9-0.4
Delay discount exponential model param0.40.41.40.50.30.70.60.00.51.20.7
Delay discount hyperbolic model param0.40.41.30.40.30.70.60.10.51.10.6
Fecal boli incidents, locomotor time 10.10.10.5-0.70.10.3-0.1-0.2-0.10.30.2
Change in fecal boli incidents, locomotor task0.50.41.30.2-1.1-0.7-0.5-0.3-0.4-0.7-0.8
Time >=10cm from walls, locomotor time 10.70.72.5-1.6-1.0-0.2-0.70.3-0.3-0.8-0.9
Bouts of movement, locomotor time 10.40.51.1-0.50.7-0.8-0.6-1.0-0.8-0.50.1
Total resting periods, locomotor time 10.40.40.8-0.60.6-0.8-0.7-0.9-0.8-0.5-0.1
Rest time, locomotor task time 11.51.72.31.11.01.51.41.41.51.21.2
Distance moved, locomotor task time 10.91.01.4-1.0-0.9-1.1-1.1-0.6-1.0-1.1-1.2
Vertical activity count, locomotor time 10.60.61.50.50.70.80.91.21.00.30.4
Time >=10cm from walls, locomotor time 20.10.10.5-0.70.1-0.2-0.3-0.2-0.2-0.1-0.2
Bouts of movement, locomotor time 20.30.30.6-0.50.3-0.8-0.6-0.7-0.7-0.5-0.2
Total resting periods, locomotor time 20.30.30.5-0.60.3-0.7-0.6-0.5-0.7-0.6-0.3
Rest time, locomotor task time 20.91.02.60.50.61.21.11.61.30.30.6
Distance moved, locomotor task time 20.30.41.2-0.2-0.3-0.7-0.6-1.1-0.8-0.1-0.3
Vertical activity count, locomotor time 21.11.22.81.70.71.01.20.51.01.31.0
Weight adjusted by age0.70.82.6-0.4-0.9-0.8-0.9-1.6-1.2-0.2-0.2
Seeking ratio, delayed vs. immediate footshock0.50.61.6-0.8-0.2-0.8-0.7-0.2-0.6-1.2-0.9
Locomotion in novel chamber2.73.46.30.81.62.31.92.52.21.41.3
Locomotion in novel chamber post-restriction1.61.93.90.61.41.61.42.01.70.80.9
Progressive ratio5.86.87.8-2.7-2.6-2.6-2.8-2.3-2.7-2.6-2.5
Food seeking constrained by brief footshock0.10.10.20.5-0.2-0.3-0.1-0.4-0.2-0.2-0.0
Seeking ratio, punishment vs. effort3.94.97.22.72.12.12.42.02.31.92.0
Run reversals in cocaine runway, females3.33.24.3-1.4-2.0-2.1-1.8-1.2-1.6-2.0-2.0
Run reversals in cocaine runway, males2.52.43.21.81.01.61.71.01.61.71.7
Latency to leave start box in cocaine runway0.80.81.3-1.2-0.8-0.8-0.9-0.3-0.7-1.1-1.1
Latency to leave start box in cocaine runway, F0.50.61.1-1.0-0.2-0.8-0.8-0.3-0.7-0.9-0.9
Latency to leave start box in cocaine runway, M0.10.10.9-0.2-0.9-0.1-0.2-0.2-0.2-0.2-0.3
Cd content in liver2.32.53.50.91.71.91.61.61.61.61.6
Co content in liver3.23.85.32.22.31.62.01.82.01.71.7
Cu content in liver0.50.71.1-0.9-0.1-1.1-0.9-0.8-0.9-0.8-0.8
Fe content in liver0.10.10.20.1-0.50.1-0.0-0.3-0.10.30.1
K content in liver4.03.95.1-1.7-2.3-2.0-2.0-1.8-2.0-2.0-2.0
Mg content in liver3.23.34.8-2.0-1.5-1.8-1.9-0.9-1.7-2.2-2.1
Mn content in liver1.21.43.2-1.1-1.0-1.1-1.3-1.8-1.5-0.4-0.5
Na content in liver0.20.31.1-0.2-0.6-0.3-0.3-1.1-0.50.10.1
Rb content in liver0.20.31.1-0.40.30.00.01.10.3-0.7-0.6
Se content in liver0.10.10.7-0.9-0.00.1-0.4-0.1-0.3-0.0-0.0
Sr content in liver0.40.41.70.30.2-0.3-0.3-1.3-0.60.60.7
Zn content in liver1.21.31.9-1.1-0.7-1.4-1.2-1.3-1.3-1.0-1.0