Hub : Genes

Kcnk6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000020598 0.04 0.03 2.0e-04 0.02 0.02 0.02 0.02 1.2e-03 4.3e-03 1.4e-03 2.6e-03
2 BLA gene expression ENSRNOG00000020598 0.23 0.13 9.5e-11 0.18 0.16 0.17 0.17 3.6e-10 5.9e-09 2.2e-09 1.5e-09
3 Brain gene expression ENSRNOG00000020598 0.05 0.03 1.4e-08 0.07 0.08 0.08 0.08 2.7e-07 6.2e-08 1.2e-07 4.1e-08
4 Eye gene expression ENSRNOG00000020598 0.37 0.21 1.2e-03 0.06 0.04 0.03 0.05 4.2e-02 8.0e-02 1.3e-01 6.0e-02
5 IL gene expression ENSRNOG00000020598 0.25 0.16 1.4e-04 0.13 0.14 0.16 0.15 5.6e-04 2.6e-04 1.0e-04 1.7e-04
6 Liver gene expression ENSRNOG00000020598 0.04 0.03 2.0e-05 0.02 0.03 0.03 0.03 2.0e-03 1.7e-04 4.9e-04 1.6e-04
7 NAcc gene expression ENSRNOG00000020598 0.06 0.04 9.2e-05 0.06 0.04 0.04 0.04 4.6e-05 5.4e-04 3.7e-04 3.2e-04
8 OFC gene expression ENSRNOG00000020598 0.15 0.11 1.4e-03 0.05 0.14 0.06 0.05 2.6e-02 3.8e-04 1.5e-02 2.5e-02
9 PL gene expression ENSRNOG00000020598 0.24 0.11 4.5e-13 0.17 0.17 0.18 0.18 5.3e-13 3.4e-13 2.3e-13 7.1e-14

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail0.20.60.90.90.60.70.80.6-0.90.60.80.6
BMI without tail0.10.30.5-0.4-0.4-0.6-0.3-0.70.6-0.4-0.6-0.5
Body weight2.711.512.4-3.0-3.4-3.5-3.3-3.53.4-3.4-3.5-3.4
Epididymis fat weight0.00.00.00.10.20.10.20.1-0.00.20.20.2
Glucose0.30.50.70.60.80.60.80.7-0.50.80.70.7
Heart weight0.60.91.4-0.3-1.1-0.9-1.2-1.00.7-1.1-1.0-1.0
Left kidney weight2.67.58.9-1.8-3.0-2.7-3.0-2.92.4-2.9-2.7-3.0
Right kidney weight4.111.612.4-2.9-3.4-3.5-3.5-3.53.4-3.4-3.5-3.4
Tail length5.416.419.2-4.1-3.8-4.2-3.8-4.14.4-3.8-4.2-3.9
Length with tail8.029.533.3-5.3-5.3-5.6-5.3-5.55.8-5.3-5.6-5.3
Length without tail3.88.38.7-2.9-2.9-2.9-2.9-2.82.9-2.9-2.9-2.8
Liver weight, left0.10.21.21.10.30.30.20.3-0.60.30.40.2
Liver weight, right0.00.00.00.1-0.2-0.1-0.1-0.1-0.1-0.2-0.1-0.1
Parametrial fat weight0.71.32.61.61.01.10.91.0-1.41.01.21.0
Retroperitoneal fat weight1.13.75.72.41.81.91.71.8-2.11.82.01.8
Intraocular pressure0.10.10.2-0.20.40.10.50.20.20.40.20.3
Extensor digitorum longus weight0.20.80.90.90.90.90.90.9-0.90.90.91.0
Soleus weight0.82.32.90.91.71.51.71.6-1.31.71.51.7
Tibialis anterior weight0.00.00.10.20.00.0-0.00.0-0.10.00.10.0
Tibia length2.05.66.0-2.0-2.4-2.4-2.4-2.52.3-2.4-2.4-2.4
Number of licking bursts2.22.63.01.71.51.71.51.7-1.71.51.71.6
Food consumed during 24 hour testing period0.40.51.0-1.0-0.6-0.7-0.6-0.60.7-0.6-0.7-0.6
Times rat made contact with spout0.50.51.31.10.60.70.60.7-0.90.60.80.6
Mean time between licks in bursts0.10.20.3-0.1-0.6-0.4-0.6-0.40.3-0.6-0.4-0.5
Mean num. licks in bursts0.80.91.2-0.7-0.9-1.1-0.9-1.10.9-0.9-1.0-1.0
Std. dev. time between licks in bursts0.70.81.1-1.0-0.8-1.1-0.8-0.91.0-0.8-1.0-0.8
Water consumed over 24 hours0.70.81.1-0.2-1.0-0.9-1.0-0.90.7-1.0-0.9-1.0
Indifference point 0 sec0.20.40.5-0.3-0.6-0.6-0.7-0.50.6-0.6-0.6-0.6
Indifference point AUC0.40.40.70.80.60.60.50.6-0.80.60.70.6
Indifference point function ln k0.40.60.8-0.9-0.7-0.7-0.8-0.70.9-0.7-0.8-0.7
Indifference point function log k0.40.60.8-0.9-0.7-0.7-0.8-0.70.9-0.7-0.8-0.7
Delay discounting total patch changes 0 sec0.30.50.6-0.6-0.7-0.7-0.8-0.60.7-0.7-0.7-0.7
Delay discounting total patch changes 12 sec0.30.40.5-0.4-0.7-0.6-0.7-0.60.5-0.7-0.6-0.6
Delay discounting total patch changes 18 sec0.10.10.30.60.30.30.20.3-0.50.30.40.3
Delay discounting total patch changes 24 sec0.70.81.4-1.2-0.8-0.9-0.9-0.91.0-0.8-0.9-0.8
Delay discounting total patch changes 6 sec0.10.10.10.1-0.3-0.3-0.4-0.30.2-0.3-0.3-0.3
Delay discounting time to switch 0 sec1.11.72.11.11.41.21.51.3-1.11.41.31.4
Delay discounting water rate 0 sec0.40.71.01.00.70.90.70.8-1.00.70.90.7
Delay discounting water rate 12 sec0.91.31.6-1.3-1.1-1.1-1.1-1.11.1-1.1-1.2-1.2
Delay discounting water rate 18 sec0.50.70.90.40.91.00.90.9-0.60.90.80.9
Delay discounting water rate 24 sec0.30.50.7-0.3-0.8-0.5-0.7-0.70.5-0.8-0.7-0.8
Delay discounting water rate 6 sec0.10.20.5-0.7-0.3-0.3-0.3-0.30.4-0.3-0.4-0.3
Locomotor activity0.50.71.41.20.80.80.80.7-0.90.80.90.7
Locomotor testing distance0.91.51.71.21.21.31.21.2-1.31.21.21.1
Locomotor testing rearing1.62.54.52.11.41.61.41.4-1.81.41.51.3
Light reinforcement 10.10.30.40.30.60.50.60.5-0.50.60.50.6
Light reinforcement 26.99.110.02.43.23.13.23.1-2.93.23.03.2
Reaction time number correct0.10.10.40.6-0.30.0-0.3-0.2-0.3-0.3-0.1-0.3
Reaction time mean minus median0.20.20.3-0.3-0.6-0.5-0.5-0.50.5-0.6-0.5-0.5
Reaction time mean minus median AUC0.30.40.6-0.2-0.8-0.6-0.7-0.60.5-0.8-0.6-0.7
Reaction time num false alarms0.91.31.51.21.11.11.11.1-1.21.11.21.1
Reaction time num false alarms AUC1.31.82.01.41.31.31.21.4-1.41.31.41.3
Reaction time trials correct on left0.10.10.40.6-0.30.0-0.3-0.2-0.3-0.3-0.1-0.3
Reaction time trials on left0.10.10.40.7-0.30.0-0.3-0.2-0.4-0.3-0.0-0.3
Reaction time mean0.10.10.10.40.20.30.30.3-0.20.20.30.3
Reaction time mean AUC0.20.20.50.70.30.50.50.5-0.40.30.50.4
Median of all reaction times0.20.30.40.50.40.50.60.6-0.40.40.60.5
Reaction time omissions0.30.31.21.10.30.60.50.5-0.60.30.50.4
Reaction time false alarm rate1.01.51.80.81.31.21.31.3-1.01.31.31.3
Reaction time premature initiation rate0.00.00.1-0.4-0.1-0.1-0.0-0.10.2-0.1-0.1-0.1
Reaction time premature initiations0.00.00.10.1-0.2-0.0-0.2-0.1-0.0-0.2-0.1-0.2
Std. dev. reaction times0.10.10.2-0.0-0.5-0.3-0.4-0.30.3-0.5-0.3-0.3
Reaction time trials completed0.10.10.40.7-0.30.0-0.3-0.2-0.4-0.3-0.0-0.3
Reaction time trials AUC0.10.10.80.9-0.20.2-0.2-0.1-0.6-0.20.1-0.2
Social response proportion4.24.65.2-1.3-2.3-2.2-2.3-2.32.0-2.3-2.3-2.3
Social responses0.10.10.2-0.3-0.2-0.4-0.1-0.30.4-0.2-0.4-0.3
Social time0.60.82.5-1.6-0.5-0.8-0.5-0.91.3-0.5-0.9-0.6
Conditioned locomotion0.40.40.70.6-0.8-0.5-0.8-0.70.1-0.8-0.5-0.8
Cocaine response after cond. corrected0.30.40.5-0.2-0.7-0.6-0.7-0.70.5-0.7-0.6-0.7
Cocaine response after cond. not corrected0.60.60.90.1-0.9-0.8-0.9-0.80.5-0.9-0.7-1.0
Cocaine response before conditioning1.41.72.5-0.4-1.5-1.3-1.6-1.40.9-1.5-1.2-1.5
Saline control response0.40.50.6-0.6-0.7-0.7-0.7-0.70.8-0.7-0.7-0.7
Condit. Reinf. active minus inactive responses4.25.25.8-1.9-2.4-2.3-2.4-2.32.1-2.4-2.3-2.4
Condit. Reinf. active-inactive response ratio2.62.83.7-0.8-1.9-1.6-1.9-1.71.3-1.9-1.6-1.9
Condit. Reinf. active responses4.96.87.1-2.4-2.6-2.6-2.7-2.62.5-2.6-2.7-2.6
Condit. Reinf. inactive responses1.72.13.5-1.9-1.3-1.5-1.3-1.31.7-1.3-1.5-1.3
Condit. Reinf. lever presses7.410.213.2-3.6-3.0-3.2-3.1-3.13.4-3.0-3.3-3.0
Condit. Reinf. lever reinforcers received5.78.18.7-2.5-2.9-2.9-2.9-2.92.7-2.9-2.9-2.9
Pavlov. Cond. lever latency3.54.86.42.52.02.22.12.1-2.42.02.32.0
Pavlov. Cond. magazine entry latency2.02.33.9-2.0-1.3-1.5-1.3-1.41.7-1.3-1.5-1.3
Pavlov. Cond. change in total contacts6.89.412.2-3.5-2.9-3.0-2.9-3.03.3-2.9-3.2-2.9
Pavlov. Cond. index score3.24.27.0-2.6-1.8-2.0-1.9-2.02.3-1.8-2.1-1.8
Pavlov. Cond. latency score3.13.96.4-2.5-1.7-2.0-1.8-1.92.2-1.7-2.0-1.7
Pavlov. Cond. lever contacts3.34.66.4-2.5-2.0-2.1-2.0-2.12.4-2.0-2.2-2.0
Pavlov. Cond. magazine entry number1.51.84.82.21.01.31.01.2-1.71.01.31.0
Pavlov. Cond. intertrial magazine entries1.11.42.81.70.91.20.91.1-1.40.91.20.9
Pavlov. Cond. lever-magazine prob. diff.3.64.77.0-2.6-1.9-2.2-2.0-2.12.4-1.9-2.2-2.0
Pavlov. Cond. response bias3.85.27.3-2.7-2.1-2.3-2.2-2.22.5-2.1-2.3-2.1
Conditioned reinforcement - actives0.20.20.4-0.2-0.5-0.6-0.5-0.60.3-0.5-0.4-0.5
Conditioned reinforcement - inactives2.12.42.6-1.3-1.6-1.5-1.5-1.61.6-1.6-1.6-1.6
Conditioned locomotion1.41.62.41.61.21.11.21.2-1.51.21.31.2
Intermittent access intake day 1-15 change1.51.52.2-1.5-1.0-1.3-1.1-1.21.5-1.0-1.2-1.1
Intermittent access intake escalation1.11.11.9-1.4-0.8-1.1-0.8-1.11.3-0.8-1.1-0.9
Intermittent access intake escalation 23.23.23.9-1.7-1.7-1.7-1.7-1.82.0-1.7-1.8-1.8
Intermitt. access day 1 inactive lever presses0.60.61.9-1.4-0.4-0.8-0.4-0.61.2-0.4-0.7-0.5
Intermitt. access day 15 inactive lever presses0.30.31.1-1.1-0.3-0.6-0.3-0.40.8-0.3-0.5-0.3
Intermitt. access escalation Index0.10.10.1-0.1-0.40.1-0.4-0.30.2-0.4-0.3-0.4
Intermittent access day 1 total infusions0.20.20.80.9-0.10.6-0.10.1-0.7-0.10.30.0
Intermittent access day 15 total infusions0.70.81.1-0.8-1.0-0.7-1.0-1.00.7-1.0-0.9-1.0
Intermittent access terminal intake (last 3 days)1.31.41.8-0.8-1.3-1.0-1.3-1.31.0-1.3-1.2-1.3
Intermittent access total infusions0.40.40.7-0.3-0.8-0.4-0.8-0.80.3-0.8-0.6-0.8
Intermittent access day 1 locomotion0.10.10.50.7-0.00.2-0.00.1-0.5-0.00.20.0
Intermittent access day 15 total locomotion0.00.00.00.10.20.20.20.1-0.10.20.20.2
Intermittent access total locomotion0.50.50.70.80.70.60.70.7-0.90.70.80.7
Intermittent access standard deviation5.45.77.9-2.8-2.2-2.4-2.2-2.42.6-2.2-2.5-2.2
Cocaine induced anxiety0.00.00.1-0.2-0.1-0.4-0.10.10.2-0.1-0.10.0
Post-drug Anxiety0.30.30.50.40.60.20.60.7-0.30.60.50.7
Baseline Anxiety0.20.20.80.90.30.50.30.3-0.60.30.50.3
Lifetime Intake0.10.10.10.3-0.30.2-0.3-0.2-0.3-0.3-0.0-0.2
Incentive Sensitization - Responses0.10.10.4-0.60.0-0.00.00.00.30.0-0.00.1
Incentive Sensitization - Breakpoint0.10.10.2-0.50.20.10.20.20.10.20.10.3
Progressive ratio test 1 active lever presses1.31.41.9-0.6-1.3-0.8-1.3-1.40.9-1.3-1.2-1.3
Progressive ratio test 1 breakpoint1.91.92.6-0.8-1.6-1.0-1.6-1.61.2-1.6-1.4-1.6
Progressive ratio test 1 inactive lever presses0.40.41.1-1.1-0.5-0.7-0.5-0.70.8-0.5-0.6-0.5
Progressive ratio test 2 active lever presses0.60.60.8-0.9-0.8-0.6-0.8-0.80.8-0.8-0.8-0.8
Progressive ratio test 2 breakpoint0.60.60.7-0.8-0.8-0.6-0.8-0.80.8-0.8-0.8-0.8
Progressive ratio test 2 inactive lever presses3.13.65.9-2.4-1.7-1.7-1.7-1.92.1-1.7-1.9-1.7
Total sessions with >9 infusions0.30.42.11.50.10.60.10.1-0.80.10.40.1
Short access day 1 total inactive lever presses0.60.61.5-1.2-0.6-0.8-0.6-0.71.0-0.6-0.8-0.6
Short access day 10 total inactive lever presses0.50.52.0-1.4-0.3-1.0-0.3-0.51.0-0.3-0.6-0.3
Short access day 1 total infusions0.20.30.50.0-0.7-0.1-0.6-0.60.1-0.7-0.5-0.7
Short access day 10 total infusions0.20.20.70.70.20.60.20.3-0.80.20.50.3
Short access total infusions0.30.41.21.10.30.70.20.4-1.00.30.60.3
Short access day 1 locomotion1.71.83.11.81.31.21.11.2-1.61.31.41.2
Short access day 10 total locomotion0.30.30.6-0.6-0.5-0.8-0.5-0.50.6-0.5-0.5-0.5
Short access total locomotion0.30.31.11.10.40.30.30.5-0.90.40.60.4
Compulsive drug intake0.40.40.6-0.7-0.5-0.8-0.5-0.60.7-0.5-0.6-0.5
One hour access (0.3 mA shock)1.41.62.7-1.6-1.1-1.4-1.1-1.21.4-1.1-1.3-1.1
One hour access (shock baseline)0.10.20.3-0.5-0.4-0.3-0.4-0.50.4-0.4-0.4-0.4
Number of responses in last shaping day2.32.32.9-1.1-1.6-1.2-1.7-1.71.4-1.6-1.6-1.7
Context. condit. distance diff. score0.10.10.10.30.20.20.30.3-0.20.20.30.2
Locomotion velocity, session 12.32.52.91.11.61.71.71.7-1.51.61.61.7
Locomotion distance, session 10.91.11.5-1.2-1.0-1.0-1.0-1.01.1-1.0-1.0-1.0
Locomotion velocity, session 20.40.50.90.90.70.60.80.6-0.70.70.70.6
Locomotion distance, session 20.50.81.41.20.70.90.80.8-1.00.70.90.7
Locomotion velocity, session 30.20.30.80.90.30.50.30.4-0.80.30.50.4
Locomotion distance, session 35.86.36.9-2.0-2.6-2.6-2.6-2.62.3-2.6-2.5-2.6
Stereotopy head waving bouts, day 30.70.92.81.70.40.90.60.7-1.30.40.80.6
Stereotopy head waving duration, day 32.83.45.12.31.61.91.71.8-2.11.61.81.7
Locomotion velocity, session 70.00.00.00.00.0-0.10.2-0.10.00.0-0.1-0.0
Locomotion distance, session 70.10.10.1-0.1-0.3-0.3-0.2-0.30.3-0.3-0.3-0.3
Stereotopy head waving bouts, day 70.10.10.60.80.10.20.20.2-0.40.10.20.1
Stereotopy head waving duration, day 71.11.32.31.51.01.11.01.1-1.31.01.11.0
Locomotion velocity, session 83.44.05.72.41.72.11.92.0-2.21.72.11.8
Locomotion distance, session 80.30.50.70.80.50.70.70.8-0.70.50.70.6
Degree of sensitization distance3.23.33.91.31.91.82.01.9-1.61.91.81.9
Degree of sensitization stereotypy0.00.00.30.50.00.10.00.0-0.30.00.1-0.0
Condit. Reinf. active minus inactive responses0.20.30.50.40.40.60.40.6-0.70.40.60.5
Condit. Reinf. active-inactive response ratio0.20.20.30.40.20.50.30.5-0.60.20.40.4
Condit. Reinf. active responses1.21.41.91.21.11.21.11.2-1.41.11.31.1
Condit. Reinf. inactive responses0.81.01.11.01.00.91.00.9-1.01.01.00.9
Incentive salience index mean0.00.00.10.30.00.20.10.2-0.30.00.20.1
Condit. Reinf. lever presses0.10.10.2-0.3-0.4-0.4-0.4-0.30.4-0.4-0.3-0.4
Time in familiar zone, hab. session 10.30.30.3-0.6-0.5-0.6-0.4-0.50.6-0.5-0.5-0.5
Time in novel zone, hab. session 10.20.20.40.70.30.40.20.3-0.50.30.40.4
Total zone transitions, hab. session 10.50.60.7-0.8-0.8-0.9-0.8-0.80.8-0.8-0.8-0.8
Total locomotion distance, hab. session 13.14.56.0-2.5-2.0-2.2-2.0-2.02.3-2.0-2.1-2.0
Locomotion velocity, hab. session 11.42.03.3-1.8-1.3-1.4-1.3-1.31.6-1.3-1.4-1.3
Time in familiar zone, hab. session 20.60.61.5-1.2-0.7-0.8-0.6-0.71.0-0.7-0.8-0.6
Time in novel zone, hab. session 20.70.70.90.90.80.80.70.8-0.90.80.90.8
Total zone transitions, hab. session 20.20.21.11.00.00.40.10.3-0.70.00.40.1
Total locomotion distance, hab. session 20.40.50.7-0.5-0.9-0.7-0.8-0.70.5-0.9-0.7-0.8
Locomotion velocity, hab. session 20.30.40.7-0.2-0.8-0.6-0.8-0.60.4-0.8-0.6-0.7
Novel to familiar place preference ratio1.11.11.4-1.0-1.0-1.1-1.0-1.21.1-1.0-1.1-1.1
Novelty place preference0.91.01.2-0.9-0.9-1.0-1.0-1.11.0-0.9-1.0-1.0
Time in novel zone, NPP test0.50.60.8-0.6-0.7-0.8-0.7-0.90.8-0.7-0.8-0.8
Total zone transitions, NPP test0.10.20.30.10.50.40.60.5-0.40.50.50.5
Total locomotion distance, NPP test1.92.64.1-2.0-1.5-1.6-1.4-1.51.8-1.5-1.6-1.5
Locomotion velocity, NPP test2.33.34.9-2.2-1.7-1.9-1.6-1.71.9-1.7-1.8-1.7
Pavlov. Cond. lever latency0.10.10.2-0.20.50.40.40.4-0.10.50.30.5
Pavlov. Cond. magazine entry latency0.10.10.20.30.30.40.40.4-0.30.30.40.4
Pavlov. Cond. change in total contacts0.00.00.00.0-0.00.0-0.00.00.0-0.00.0-0.0
Pavlov. Cond. index score0.00.00.20.5-0.10.0-0.10.0-0.2-0.10.1-0.1
Pavlov. Cond. latency score0.00.00.10.3-0.3-0.1-0.2-0.1-0.0-0.3-0.1-0.3
Pavlov. Cond. lever contacts0.70.81.0-0.5-1.0-1.0-0.9-0.90.8-1.0-0.9-1.0
Pavlov. Cond. magazine entry number0.10.10.1-0.3-0.2-0.3-0.2-0.30.3-0.2-0.3-0.2
Pavlov. Cond. intertrial magazine entries0.20.20.60.80.30.40.30.3-0.60.30.40.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.20.5-0.4-0.1-0.3-0.2-0.0-0.4-0.1-0.4
Pavlov. Cond. response bias0.10.10.1-0.1-0.4-0.3-0.3-0.20.2-0.4-0.2-0.3
Bone: apparent density0.10.10.20.40.40.30.40.3-0.30.40.30.3
Bone surface0.20.30.5-0.5-0.5-0.7-0.5-0.60.7-0.5-0.6-0.6
Bone volume0.20.30.5-0.5-0.5-0.7-0.5-0.60.7-0.5-0.6-0.6
Bone: connectivity density0.50.91.20.71.10.81.00.9-0.71.10.91.0
Bone: cortical apparent density2.22.93.31.71.61.81.71.7-1.81.61.81.6
Bone: cortical area2.23.34.0-1.4-2.0-1.8-1.8-1.81.7-2.0-1.8-1.9
Bone: cortical porosity1.01.13.21.80.81.00.70.8-1.40.81.00.8
Bone: cortical porosity1.21.23.61.90.81.00.80.9-1.40.81.10.8
Bone: cortical thickness0.91.62.2-0.8-1.5-1.2-1.3-1.21.0-1.5-1.2-1.4
Bone: cortical thickness0.20.21.11.10.00.40.20.3-0.70.00.40.1
Bone: cortical tissue density2.63.43.91.81.71.91.81.9-2.01.71.91.8
Bone: elastic displacement0.10.10.10.10.30.20.30.2-0.20.30.20.3
Bone: elastic work2.22.83.2-1.4-1.8-1.7-1.7-1.71.6-1.8-1.7-1.8
Bone: endosteal estimation1.22.73.3-1.8-1.5-1.7-1.5-1.61.8-1.5-1.7-1.6
Bone: endosteal perimeter1.22.53.9-2.0-1.4-1.7-1.4-1.51.8-1.4-1.6-1.4
Bone: final force1.82.93.5-1.4-1.9-1.7-1.7-1.71.6-1.9-1.7-1.8
Bone: final moment2.64.35.1-1.7-2.3-2.1-2.1-2.11.9-2.3-2.1-2.2
Bone: marrow area1.32.83.4-1.8-1.6-1.8-1.5-1.71.8-1.6-1.7-1.6
Bone: maximum diameter1.42.73.0-1.4-1.7-1.7-1.6-1.61.6-1.7-1.7-1.7
Bone: maximum force3.05.25.8-2.1-2.4-2.3-2.3-2.22.2-2.4-2.3-2.3
Bone: maximum moment3.96.97.6-2.4-2.8-2.6-2.6-2.62.6-2.8-2.6-2.7
Bone: minimum diameter5.810.711.6-2.9-3.4-3.3-3.3-3.33.1-3.4-3.3-3.4
Bone: periosteal estimation2.24.54.7-1.9-2.2-2.2-2.0-2.12.1-2.2-2.2-2.2
Bone: periosteal perimeter1.93.23.7-1.9-1.7-1.8-1.7-1.81.9-1.7-1.8-1.7
Bone: post-yield work0.91.22.4-1.6-1.0-1.1-0.9-0.91.3-1.0-1.1-0.9
Bone: stiffness1.62.52.9-1.5-1.7-1.6-1.5-1.51.5-1.7-1.6-1.6
Bone: tissue strength4.54.44.8-2.0-2.0-2.1-2.1-2.12.2-2.0-2.1-2.1
Bone: trabecular number0.10.10.2-0.3-0.2-0.4-0.2-0.30.4-0.2-0.3-0.3
Bone: trabecular spacing1.72.22.4-1.4-1.5-1.5-1.5-1.51.5-1.5-1.5-1.5
Bone: trabecular thickness0.30.31.01.00.40.50.50.5-0.70.40.60.4
Bone: trabecular tissue density2.63.64.01.81.92.02.01.9-2.01.91.91.8
Breakpoint value in progressive ratio session2.02.23.6-1.9-1.4-1.3-1.2-1.41.8-1.4-1.6-1.3
Distance traveled before self-admin1.81.92.5-1.0-1.4-1.2-1.6-1.51.3-1.4-1.4-1.5
Distance traveled after self-admin5.45.96.4-2.5-2.3-2.5-2.4-2.52.5-2.3-2.5-2.3
Delta time in closed arm before/after self-admin0.60.61.0-1.0-0.6-1.0-0.5-0.81.0-0.6-0.8-0.6
Delta time in open arm before/after self-admin0.10.10.50.60.00.50.10.2-0.70.00.30.0
Diff in mean of infusions in LGA sessions0.10.10.2-0.5-0.4-0.2-0.3-0.30.4-0.4-0.4-0.3
Extinction: sum of active levers before priming1.41.42.3-1.5-1.1-1.2-1.0-1.11.2-1.1-1.2-1.1
Active lever presses in extinction session 60.60.51.1-1.1-0.6-0.8-0.4-0.61.0-0.6-0.7-0.6
Delta distance traveled before/after self-admin0.80.92.4-1.5-0.6-1.1-0.5-0.81.2-0.6-0.9-0.6
Delta ambulatory time before/after self-admin1.31.42.0-1.4-1.0-1.4-0.9-1.21.4-1.0-1.2-1.0
Time in closed arm before self-admin0.20.20.70.90.10.60.00.4-0.50.10.30.2
Time in closed arm after self-admin0.20.20.5-0.3-0.3-0.5-0.3-0.40.7-0.3-0.5-0.2
Time in open arm before self-admin1.41.51.9-1.2-1.2-1.4-1.0-1.31.3-1.2-1.2-1.2
Time in open arm after self-admin0.91.01.6-0.4-1.2-0.8-1.1-1.10.5-1.2-0.9-1.3
Sum of active levers in priming session hrs 5-60.10.10.20.1-0.4-0.1-0.2-0.10.0-0.4-0.2-0.3
Time to tail flick, vehicle, before self-admin0.20.20.80.9-0.3-0.3-0.4-0.2-0.2-0.3-0.0-0.3
Time to tail flick, vehicle, after self-admin0.20.20.7-0.8-0.2-0.3-0.4-0.50.6-0.2-0.5-0.3
Time to tail flick, test, before self-admin0.10.10.50.7-0.2-0.2-0.3-0.1-0.1-0.20.0-0.2
Time to tail flick, test, after self-admin0.10.10.50.7-0.2-0.1-0.20.0-0.3-0.20.1-0.1
Delta time to tail flick, vehicle, before/after SA0.20.20.9-0.9-0.2-0.2-0.2-0.40.6-0.2-0.5-0.2
Delta time to tail flick, test, before/after SA0.00.00.20.4-0.00.10.00.1-0.4-0.00.10.0
Ambulatory time before self-admin1.01.01.4-0.8-1.0-0.9-1.2-1.11.0-1.0-1.1-1.0
Ambulatory time after self-admin5.86.47.3-2.7-2.3-2.6-2.5-2.62.7-2.3-2.7-2.4
Total heroin consumption1.72.12.4-1.3-1.6-1.3-1.5-1.41.4-1.6-1.4-1.5
Area under the delay curve0.20.21.2-1.1-0.1-0.4-0.0-0.10.8-0.1-0.3-0.0
Delay disc. indifference point, 0s delay0.70.71.4-1.2-0.7-1.0-0.5-0.71.2-0.7-0.8-0.6
Delay disc. indifference point, 16s delay1.71.83.9-2.0-1.0-1.4-1.0-1.01.8-1.0-1.3-1.0
Delay disc. indifference point, 2s delay0.40.42.7-1.70.1-0.20.30.00.80.1-0.20.2
Delay disc. indifference point, 24s delay1.61.52.5-1.6-1.0-1.3-1.1-1.11.6-1.0-1.2-1.0
Delay disc. indifference point, 4s delay0.10.10.3-0.4-0.2-0.3-0.1-0.20.5-0.2-0.3-0.2
Delay disc. indifference point, 8s delay0.60.71.00.30.90.81.00.9-0.40.90.71.0
Delay discount exponential model param0.20.31.31.10.10.40.10.1-0.80.10.30.1
Delay discount hyperbolic model param0.20.21.21.1-0.00.3-0.10.0-0.7-0.00.2-0.1
Fecal boli incidents, locomotor time 13.33.64.51.62.11.82.11.9-1.62.11.82.0
Change in fecal boli incidents, locomotor task0.20.20.3-0.2-0.5-0.4-0.5-0.40.4-0.5-0.4-0.4
Time >=10cm from walls, locomotor time 10.00.00.30.50.20.10.10.1-0.00.20.10.2
Bouts of movement, locomotor time 10.50.51.6-1.1-0.2-0.7-0.4-0.61.3-0.2-0.8-0.3
Total resting periods, locomotor time 10.40.41.5-1.2-0.1-0.6-0.3-0.51.1-0.1-0.7-0.2
Rest time, locomotor task time 10.10.10.10.40.30.20.30.3-0.20.30.30.3
Distance moved, locomotor task time 10.10.10.20.1-0.4-0.3-0.4-0.40.0-0.4-0.2-0.4
Vertical activity count, locomotor time 11.11.21.6-0.6-1.2-1.1-1.1-1.30.9-1.2-1.1-1.2
Time >=10cm from walls, locomotor time 20.00.00.00.1-0.2-0.1-0.2-0.1-0.1-0.2-0.0-0.1
Bouts of movement, locomotor time 20.10.20.3-0.50.40.10.50.50.10.40.30.5
Total resting periods, locomotor time 20.10.20.3-0.20.40.20.40.5-0.00.40.40.6
Rest time, locomotor task time 20.20.20.40.4-0.5-0.4-0.6-0.50.3-0.5-0.5-0.6
Distance moved, locomotor task time 20.00.10.10.10.20.20.20.2-0.40.20.30.2
Vertical activity count, locomotor time 20.20.20.5-0.7-0.2-0.5-0.2-0.40.5-0.2-0.4-0.3
Weight adjusted by age0.20.20.50.70.40.40.40.4-0.70.30.50.3
Seeking ratio, delayed vs. immediate footshock1.41.62.5-1.6-1.3-1.0-1.2-1.31.2-1.2-1.3-1.2
Locomotion in novel chamber0.40.40.70.10.80.60.80.6-0.40.80.60.7
Locomotion in novel chamber post-restriction0.10.10.9-1.0-0.10.00.0-0.10.4-0.1-0.3-0.1
Progressive ratio0.40.50.8-0.30.90.30.90.7-0.30.80.60.8
Food seeking constrained by brief footshock3.34.05.5-2.3-2.0-2.0-1.9-2.02.0-1.9-2.0-1.9
Seeking ratio, punishment vs. effort1.92.33.2-0.9-1.8-1.2-1.7-1.61.3-1.7-1.6-1.6
Run reversals in cocaine runway, females0.30.30.40.10.60.50.60.6-0.30.60.50.6
Run reversals in cocaine runway, males1.21.22.01.40.81.40.81.0-1.30.81.00.8
Latency to leave start box in cocaine runway0.00.00.10.20.20.10.20.2-0.20.20.20.2
Latency to leave start box in cocaine runway, F0.40.50.70.80.60.70.60.7-0.80.60.70.7
Latency to leave start box in cocaine runway, M0.10.10.3-0.5-0.1-0.3-0.1-0.30.5-0.1-0.3-0.2
Cd content in liver0.30.30.40.20.60.60.60.6-0.50.60.60.6
Co content in liver1.82.22.41.41.41.51.51.5-1.51.41.51.5
Cu content in liver1.21.51.8-0.9-1.4-1.1-1.3-1.21.1-1.4-1.2-1.3
Fe content in liver0.30.40.60.10.70.60.80.6-0.30.70.60.7
K content in liver0.60.60.8-0.3-0.9-0.7-0.9-0.80.6-0.9-0.7-0.9
Mg content in liver0.10.10.20.5-0.4-0.0-0.3-0.1-0.2-0.4-0.1-0.3
Mn content in liver0.50.50.90.9-0.9-0.4-0.9-0.7-0.1-0.9-0.4-0.9
Na content in liver5.25.56.1-1.8-2.4-2.5-2.4-2.52.3-2.4-2.4-2.5
Rb content in liver0.00.00.0-0.10.0-0.1-0.1-0.00.10.0-0.10.0
Se content in liver4.04.88.93.01.82.22.02.0-2.61.82.31.8
Sr content in liver0.90.81.31.10.80.90.80.8-1.00.80.90.8
Zn content in liver0.30.30.40.50.50.60.60.6-0.70.50.60.5