Hub : Genes

Pip5k1c

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000020577 0.04 0.03 2.0e-04 0.03 0.03 0.02 0.03 1.1e-04 6.0e-04 1.4e-03 2.0e-04
2 BLA mRNA stability ENSRNOG00000020577 0.16 0.1 2.0e-08 0.13 0.16 0.13 0.13 1.6e-07 1.1e-08 1.7e-07 2.3e-07
3 Brain alternative polyA ENSRNOT00000107025 0.13 0.08 2.9e-11 0.1 0.1 0.09 0.09 2.4e-09 5.9e-10 1.1e-08 5.8e-09
4 Brain gene expression ENSRNOG00000020577 0.18 0.12 1.8e-05 0.06 0.06 0.05 0.06 3.8e-06 2.2e-06 1.8e-05 5.8e-06
5 Brain mRNA stability ENSRNOG00000020577 0.18 0.1 5.6e-17 0.12 0.16 0.14 0.15 1.8e-11 9.8e-15 4.6e-13 9.8e-14
6 Eye isoform ratio ENSRNOT00000061159 0.25 0.19 8.3e-03 0.04 0.06 -0.01 0.04 8.5e-02 4.0e-02 4.2e-01 9.2e-02
7 IL gene expression ENSRNOG00000020577 0.18 0.12 1.6e-03 0.03 0.03 0.03 0.03 5.6e-02 7.6e-02 6.1e-02 5.8e-02
8 IL isoform ratio ENSRNOT00000061159 0.16 0.12 2.8e-03 0.01 0.03 0 0.02 1.5e-01 5.6e-02 3.2e-01 1.1e-01
9 IL mRNA stability ENSRNOG00000020577 0.5 0.21 5.2e-09 0.2 0.19 0.26 0.27 1.4e-05 2.0e-05 5.4e-07 3.4e-07
10 LHb gene expression ENSRNOG00000020577 0.18 0.12 8.6e-04 0.09 0.02 0.03 0.07 4.4e-03 9.6e-02 7.6e-02 1.1e-02
11 NAcc mRNA stability ENSRNOG00000020577 0.1 0.07 4.9e-07 0.08 0.06 0.08 0.07 8.8e-07 2.3e-05 2.2e-06 2.9e-06
12 OFC mRNA stability ENSRNOG00000020577 0.36 0.18 8.0e-09 0.23 0.3 0.27 0.28 4.0e-06 8.2e-08 3.5e-07 3.1e-07
13 PL mRNA stability ENSRNOG00000020577 0.38 0.24 0.0e+00 0.27 0.31 0.3 0.32 1.2e-20 2.5e-24 2.4e-23 3.9e-25

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail6.220.122.7-4.64.7-4.6-0.54.7-4.8-4.64.64.8-4.74.54.74.7
BMI without tail2.34.96.9-2.02.4-2.40.62.4-2.3-2.02.02.3-2.62.42.22.4
Body weight1.14.85.8-2.22.3-2.3-0.12.3-2.3-2.22.22.4-2.22.42.32.4
Epididymis fat weight0.10.30.80.8-0.40.30.9-0.40.50.7-0.7-0.50.1-0.3-0.7-0.4
Glucose1.11.72.0-1.31.4-1.4-0.01.4-1.4-1.31.31.4-1.41.41.41.4
Heart weight0.30.40.90.8-0.50.41.0-0.50.60.9-0.8-0.60.2-0.4-0.7-0.6
Left kidney weight0.10.31.10.0-0.60.7-1.1-0.60.40.1-0.1-0.50.6-0.8-0.2-0.6
Right kidney weight1.54.25.22.0-2.22.2-0.1-2.22.22.0-2.0-2.22.0-2.3-2.1-2.3
Tail length2.88.510.83.3-2.92.81.4-3.03.13.3-3.3-3.02.7-2.6-3.2-2.9
Length with tail1.86.68.32.6-2.72.70.2-2.72.72.6-2.6-2.72.9-2.5-2.7-2.6
Length without tail0.20.41.5-0.0-0.60.7-1.2-0.60.40.0-0.0-0.41.0-0.7-0.2-0.5
Liver weight, left2.64.15.5-1.92.2-2.20.32.2-2.1-1.91.92.2-2.32.12.02.1
Liver weight, right1.62.73.2-1.81.7-1.6-0.51.7-1.7-1.81.81.7-1.61.61.81.7
Parametrial fat weight0.40.81.11.0-0.80.80.6-0.90.91.0-1.0-0.90.9-0.6-1.0-0.7
Retroperitoneal fat weight0.51.73.0-1.01.4-1.40.51.4-1.3-1.11.11.5-1.21.71.21.6
Intraocular pressure0.20.32.70.40.3-0.41.70.20.00.5-0.50.1-0.70.4-0.20.1
Extensor digitorum longus weight4.518.222.1-3.94.7-4.70.84.6-4.5-3.94.04.6-4.74.64.34.6
Soleus weight8.524.828.3-5.25.2-5.1-0.95.2-5.3-5.25.25.3-5.05.05.35.2
Tibialis anterior weight0.93.13.7-1.91.8-1.8-0.41.8-1.9-1.91.91.9-1.81.61.91.7
Tibia length0.82.22.91.7-1.51.50.7-1.51.61.7-1.7-1.51.4-1.3-1.7-1.4
Number of licking bursts0.30.41.90.20.6-0.61.40.5-0.30.1-0.10.5-0.60.80.10.6
Food consumed during 24 hour testing period0.50.60.7-0.70.8-0.8-0.10.8-0.8-0.70.70.8-0.80.80.80.8
Times rat made contact with spout0.30.30.6-0.30.7-0.70.80.6-0.5-0.30.30.6-0.80.70.40.6
Mean time between licks in bursts3.65.06.52.6-2.22.11.2-2.22.42.5-2.5-2.32.1-2.0-2.5-2.2
Mean num. licks in bursts0.00.10.4-0.3-0.10.1-0.6-0.0-0.1-0.20.2-0.00.0-0.20.1-0.2
Std. dev. time between licks in bursts1.11.32.00.8-1.31.3-0.9-1.21.10.8-0.8-1.21.4-1.3-0.9-1.2
Water consumed over 24 hours0.50.51.7-1.00.4-0.4-1.30.5-0.7-1.01.00.6-0.30.30.80.5
Indifference point 0 sec0.10.20.3-0.50.4-0.4-0.40.4-0.5-0.60.60.5-0.20.50.50.5
Indifference point AUC1.01.11.41.2-1.01.00.5-1.11.11.2-1.2-1.10.8-1.1-1.2-1.1
Indifference point function ln k0.20.30.5-0.50.6-0.6-0.00.6-0.6-0.60.60.7-0.50.70.60.7
Indifference point function log k0.20.30.5-0.50.6-0.6-0.00.6-0.6-0.60.60.7-0.50.70.60.7
Delay discounting total patch changes 0 sec0.10.20.3-0.40.4-0.4-0.20.4-0.4-0.50.50.5-0.30.50.50.5
Delay discounting total patch changes 12 sec0.40.51.1-0.40.8-0.90.80.8-0.7-0.40.40.7-1.10.90.50.8
Delay discounting total patch changes 18 sec0.91.21.51.2-1.11.10.3-1.11.21.2-1.2-1.11.1-1.0-1.2-1.1
Delay discounting total patch changes 24 sec0.10.10.20.3-0.40.4-0.1-0.40.30.3-0.3-0.40.3-0.5-0.3-0.5
Delay discounting total patch changes 6 sec0.10.20.40.6-0.50.50.1-0.50.50.5-0.5-0.50.7-0.4-0.5-0.4
Delay discounting time to switch 0 sec1.42.13.5-1.91.2-1.1-1.61.3-1.5-1.81.81.3-0.91.01.71.2
Delay discounting water rate 0 sec0.20.32.70.70.2-0.31.60.10.10.5-0.50.1-0.40.5-0.30.2
Delay discounting water rate 12 sec1.32.03.3-0.71.6-1.71.51.5-1.3-0.80.81.5-1.81.81.11.6
Delay discounting water rate 18 sec0.81.08.01.00.4-0.62.80.30.10.9-0.90.1-0.90.8-0.50.4
Delay discounting water rate 24 sec1.41.98.80.21.4-1.53.01.2-0.80.0-0.01.1-1.61.90.41.4
Delay discounting water rate 6 sec0.50.74.41.1-0.20.12.1-0.30.61.1-1.1-0.30.00.0-0.8-0.3
Locomotor activity3.75.98.82.1-2.72.7-0.9-2.62.52.1-2.1-2.63.0-2.7-2.3-2.6
Locomotor testing distance2.13.55.01.7-2.12.1-0.5-2.02.01.7-1.7-2.02.2-2.0-1.9-1.9
Locomotor testing rearing0.00.00.20.3-0.10.10.4-0.10.20.3-0.3-0.1-0.00.1-0.2-0.0
Light reinforcement 15.49.911.43.1-3.33.30.3-3.33.33.2-3.2-3.33.4-3.2-3.3-3.3
Light reinforcement 21.72.22.81.5-1.61.60.1-1.61.61.5-1.5-1.51.7-1.4-1.6-1.5
Reaction time number correct0.81.12.0-0.51.2-1.21.21.1-0.9-0.60.61.1-1.41.30.81.2
Reaction time mean minus median0.91.11.41.1-1.11.1-0.0-1.11.11.1-1.0-1.21.1-1.1-1.1-1.0
Reaction time mean minus median AUC0.30.42.6-0.2-0.60.7-1.6-0.50.3-0.10.2-0.50.8-0.7-0.1-0.4
Reaction time num false alarms0.10.10.3-0.00.3-0.30.50.3-0.2-0.10.10.3-0.40.30.10.2
Reaction time num false alarms AUC0.20.30.8-0.10.5-0.60.90.5-0.4-0.10.10.4-0.80.60.20.5
Reaction time trials correct on left0.81.12.0-0.51.2-1.21.21.1-0.9-0.60.61.1-1.41.30.81.2
Reaction time trials on left0.81.11.9-0.51.2-1.21.11.1-0.9-0.60.61.1-1.41.30.81.2
Reaction time mean0.10.21.5-0.2-0.40.4-1.2-0.30.1-0.20.2-0.20.5-0.40.1-0.2
Reaction time mean AUC0.10.21.5-0.3-0.30.3-1.2-0.20.0-0.30.3-0.10.4-0.30.2-0.1
Median of all reaction times0.30.41.8-0.70.2-0.1-1.30.3-0.5-0.80.80.3-0.00.10.60.3
Reaction time omissions0.30.40.60.6-0.70.7-0.2-0.70.70.5-0.5-0.70.8-0.6-0.6-0.6
Reaction time false alarm rate0.00.00.0-0.10.0-0.0-0.10.0-0.0-0.10.10.0-0.1-0.10.1-0.0
Reaction time premature initiation rate0.81.12.11.4-0.80.81.2-0.91.11.3-1.3-0.90.8-0.6-1.2-0.8
Reaction time premature initiations0.50.73.91.3-0.20.22.0-0.30.61.1-1.1-0.40.10.1-0.9-0.3
Std. dev. reaction times0.40.50.70.5-0.80.9-0.6-0.80.70.5-0.5-0.80.8-0.8-0.6-0.7
Reaction time trials completed0.81.11.9-0.51.2-1.21.11.1-0.9-0.60.61.1-1.41.30.81.2
Reaction time trials AUC0.81.12.1-0.41.2-1.31.41.1-0.9-0.50.51.0-1.41.40.71.2
Social response proportion0.70.71.20.6-0.90.9-0.4-0.90.80.7-0.7-1.00.9-1.1-0.8-1.0
Social responses7.810.113.42.8-3.43.4-0.6-3.43.32.9-2.9-3.53.4-3.7-3.1-3.6
Social time0.71.01.3-0.91.1-1.10.21.0-1.0-0.90.91.1-1.01.11.01.1
Conditioned locomotion2.12.53.9-1.11.8-1.91.21.7-1.5-1.11.11.7-2.02.01.31.8
Cocaine response after cond. corrected5.66.38.6-2.02.8-2.81.12.7-2.6-2.12.12.7-2.92.92.32.8
Cocaine response after cond. not corrected6.16.89.4-2.12.9-2.91.22.8-2.6-2.12.12.8-3.03.12.42.9
Cocaine response before conditioning0.50.60.90.6-0.90.9-0.4-0.90.80.7-0.7-0.90.9-0.9-0.7-0.9
Saline control response0.10.10.2-0.20.4-0.40.40.3-0.3-0.20.20.3-0.40.40.20.3
Condit. Reinf. active minus inactive responses2.02.53.81.9-1.41.31.4-1.51.71.9-1.9-1.51.2-1.2-1.8-1.5
Condit. Reinf. active-inactive response ratio0.40.43.10.70.2-0.31.80.10.20.6-0.60.0-0.40.4-0.40.1
Condit. Reinf. active responses2.23.03.51.9-1.81.70.5-1.81.91.9-1.9-1.81.7-1.7-1.9-1.8
Condit. Reinf. inactive responses1.41.82.41.1-1.51.5-0.5-1.41.41.1-1.1-1.51.5-1.6-1.3-1.5
Condit. Reinf. lever presses2.12.93.92.0-1.61.51.1-1.61.82.0-2.0-1.71.4-1.4-1.9-1.7
Condit. Reinf. lever reinforcers received1.62.32.91.7-1.41.40.8-1.51.61.7-1.7-1.61.3-1.4-1.7-1.6
Pavlov. Cond. lever latency0.91.21.4-1.01.2-1.20.01.2-1.2-1.11.11.2-1.11.21.11.2
Pavlov. Cond. magazine entry latency0.60.71.00.7-0.90.9-0.3-0.90.90.7-0.7-0.91.0-0.9-0.8-0.8
Pavlov. Cond. change in total contacts0.81.21.41.1-1.11.10.3-1.11.11.2-1.2-1.21.0-1.1-1.2-1.2
Pavlov. Cond. index score1.01.31.51.1-1.21.20.1-1.21.21.2-1.1-1.21.1-1.1-1.2-1.2
Pavlov. Cond. latency score0.91.21.41.0-1.21.2-0.1-1.21.21.0-1.0-1.21.2-1.1-1.1-1.1
Pavlov. Cond. lever contacts0.71.01.31.1-1.01.00.4-1.01.11.1-1.1-1.10.9-1.0-1.1-1.0
Pavlov. Cond. magazine entry number1.01.21.6-1.01.2-1.20.31.2-1.1-1.01.01.2-1.31.21.11.2
Pavlov. Cond. intertrial magazine entries0.50.71.2-0.40.9-1.00.70.9-0.8-0.50.50.9-0.91.10.71.0
Pavlov. Cond. lever-magazine prob. diff.1.01.31.51.1-1.21.2-0.1-1.21.21.1-1.1-1.21.2-1.2-1.2-1.2
Pavlov. Cond. response bias1.82.43.01.7-1.61.50.6-1.61.71.7-1.7-1.61.4-1.5-1.7-1.6
Conditioned reinforcement - actives2.72.73.21.7-1.71.70.1-1.71.71.6-1.7-1.81.6-1.7-1.7-1.8
Conditioned reinforcement - inactives0.91.01.9-0.61.1-1.20.91.1-0.9-0.60.61.1-1.01.40.81.2
Conditioned locomotion7.89.310.73.2-3.13.10.7-3.23.33.2-3.2-3.23.0-3.0-3.3-3.2
Intermittent access intake day 1-15 change6.36.28.02.8-2.52.41.1-2.52.72.8-2.8-2.52.5-2.2-2.8-2.4
Intermittent access intake escalation5.65.68.62.9-2.12.02.1-2.22.52.9-2.9-2.22.0-1.7-2.7-2.1
Intermittent access intake escalation 27.06.910.23.2-2.42.32.1-2.52.83.2-3.2-2.62.2-2.1-3.0-2.4
Intermitt. access day 1 inactive lever presses0.40.41.30.9-0.40.31.1-0.50.60.9-0.8-0.50.3-0.3-0.7-0.5
Intermitt. access day 15 inactive lever presses0.30.40.60.8-0.50.40.8-0.50.60.8-0.8-0.50.5-0.2-0.7-0.4
Intermitt. access escalation Index0.30.32.2-0.7-0.00.1-1.50.1-0.3-0.70.70.10.1-0.20.50.0
Intermittent access day 1 total infusions0.10.10.1-0.30.2-0.2-0.20.3-0.3-0.30.30.3-0.10.30.30.3
Intermittent access day 15 total infusions1.51.72.81.7-1.21.11.1-1.21.41.6-1.6-1.21.2-0.9-1.5-1.1
Intermittent access terminal intake (last 3 days)1.01.11.51.2-1.11.10.4-1.11.21.2-1.2-1.11.0-1.0-1.2-1.0
Intermittent access total infusions0.10.20.30.6-0.30.30.5-0.30.40.5-0.5-0.30.4-0.1-0.5-0.2
Intermittent access day 1 locomotion0.20.20.40.6-0.40.40.5-0.40.50.6-0.6-0.40.5-0.2-0.6-0.3
Intermittent access day 15 total locomotion3.13.34.62.2-1.81.71.0-1.82.02.1-2.1-1.81.8-1.5-2.0-1.7
Intermittent access total locomotion0.91.11.41.2-1.01.00.4-1.11.11.1-1.1-1.01.2-0.9-1.1-0.9
Intermittent access standard deviation2.93.14.32.1-1.71.61.1-1.71.92.0-2.0-1.81.5-1.5-2.0-1.7
Cocaine induced anxiety1.11.22.20.6-1.31.3-1.1-1.21.00.7-0.7-1.21.2-1.5-0.9-1.3
Post-drug Anxiety0.91.02.40.3-1.11.2-1.6-1.00.80.3-0.3-1.11.0-1.5-0.6-1.2
Baseline Anxiety0.10.10.50.30.1-0.10.70.00.10.2-0.30.0-0.10.2-0.20.1
Lifetime Intake0.00.10.10.3-0.20.20.1-0.20.30.3-0.3-0.20.3-0.1-0.3-0.1
Incentive Sensitization - Responses0.30.30.60.8-0.40.40.7-0.50.60.7-0.7-0.60.2-0.4-0.7-0.5
Incentive Sensitization - Breakpoint0.40.40.60.8-0.60.50.6-0.60.70.8-0.8-0.70.3-0.6-0.7-0.6
Progressive ratio test 1 active lever presses0.20.20.4-0.20.5-0.50.40.5-0.4-0.30.30.5-0.50.70.30.6
Progressive ratio test 1 breakpoint0.20.30.4-0.30.6-0.60.30.5-0.5-0.40.40.6-0.60.70.40.6
Progressive ratio test 1 inactive lever presses0.00.00.00.1-0.10.1-0.0-0.10.10.0-0.1-0.00.1-0.0-0.1-0.0
Progressive ratio test 2 active lever presses0.20.20.50.7-0.30.30.7-0.40.50.6-0.6-0.40.2-0.2-0.6-0.3
Progressive ratio test 2 breakpoint0.30.30.50.7-0.60.60.2-0.60.60.6-0.6-0.60.5-0.6-0.6-0.6
Progressive ratio test 2 inactive lever presses0.10.10.10.2-0.30.3-0.1-0.30.30.2-0.2-0.30.3-0.2-0.3-0.2
Total sessions with >9 infusions0.10.10.9-0.1-0.30.4-0.9-0.30.2-0.10.1-0.30.3-0.5-0.0-0.3
Short access day 1 total inactive lever presses0.00.00.00.2-0.10.10.1-0.20.20.2-0.2-0.20.1-0.1-0.2-0.1
Short access day 10 total inactive lever presses0.10.10.80.40.0-0.00.9-0.10.20.4-0.4-0.0-0.00.2-0.30.0
Short access day 1 total infusions0.30.31.00.1-0.60.6-1.0-0.50.40.1-0.1-0.50.6-0.7-0.3-0.5
Short access day 10 total infusions0.00.00.00.2-0.00.10.1-0.10.10.1-0.1-0.1-0.00.0-0.10.0
Short access total infusions0.00.00.3-0.0-0.20.2-0.6-0.20.1-0.10.0-0.20.1-0.3-0.0-0.1
Short access day 1 locomotion0.90.91.90.9-1.11.1-0.4-1.11.00.8-0.9-1.01.4-0.9-0.9-0.9
Short access day 10 total locomotion3.84.25.72.4-2.01.91.1-2.02.22.3-2.4-2.02.0-1.7-2.3-1.9
Short access total locomotion1.01.01.31.0-1.11.1-0.0-1.11.11.0-1.0-1.01.1-1.0-1.0-0.9
Compulsive drug intake0.80.81.4-1.20.8-0.8-0.70.9-1.0-1.11.10.9-0.70.71.10.8
One hour access (0.3 mA shock)0.20.30.4-0.40.5-0.50.10.5-0.5-0.50.40.6-0.40.70.50.6
One hour access (shock baseline)0.10.10.60.40.1-0.10.80.00.10.3-0.30.00.00.3-0.20.2
Number of responses in last shaping day0.20.20.30.4-0.50.5-0.1-0.50.50.4-0.4-0.40.5-0.4-0.5-0.4
Context. condit. distance diff. score0.30.40.5-0.50.7-0.70.10.7-0.6-0.60.60.7-0.60.70.60.7
Locomotion velocity, session 10.91.01.80.5-1.21.2-1.2-1.10.90.5-0.5-1.11.2-1.3-0.7-1.2
Locomotion distance, session 10.50.63.1-0.1-0.80.8-1.8-0.70.4-0.10.1-0.61.0-1.0-0.2-0.8
Locomotion velocity, session 24.04.77.11.6-2.52.5-1.5-2.42.21.6-1.6-2.32.6-2.7-1.9-2.5
Locomotion distance, session 22.02.84.61.0-1.92.0-1.7-1.81.61.0-1.0-1.82.1-2.1-1.3-1.9
Locomotion velocity, session 35.76.77.72.7-2.62.60.7-2.72.72.7-2.7-2.72.5-2.5-2.8-2.7
Locomotion distance, session 30.00.00.10.1-0.0-0.00.3-0.00.00.1-0.1-0.0-0.1-0.0-0.1-0.1
Stereotopy head waving bouts, day 34.65.56.42.2-2.52.5-0.2-2.52.52.2-2.2-2.52.5-2.5-2.4-2.5
Stereotopy head waving duration, day 35.26.37.22.5-2.72.70.0-2.72.72.5-2.5-2.72.6-2.6-2.6-2.7
Locomotion velocity, session 70.80.91.20.8-1.11.1-0.3-1.01.00.8-0.8-1.01.1-1.1-0.9-1.1
Locomotion distance, session 70.10.20.7-0.10.5-0.50.80.4-0.3-0.00.10.4-0.60.50.20.4
Stereotopy head waving bouts, day 70.20.32.0-0.3-0.40.5-1.4-0.30.1-0.30.3-0.20.6-0.50.1-0.3
Stereotopy head waving duration, day 70.50.62.30.1-0.80.9-1.5-0.80.50.1-0.1-0.71.0-0.9-0.3-0.7
Locomotion velocity, session 80.91.13.40.3-1.21.3-1.8-1.10.80.3-0.3-1.01.4-1.4-0.6-1.1
Locomotion distance, session 80.10.20.30.2-0.50.5-0.6-0.50.40.2-0.2-0.40.6-0.6-0.3-0.5
Degree of sensitization distance0.40.40.4-0.60.6-0.6-0.20.6-0.6-0.60.60.6-0.60.60.60.6
Degree of sensitization stereotypy1.51.62.6-1.61.0-1.0-1.41.1-1.3-1.61.61.2-0.90.91.51.2
Condit. Reinf. active minus inactive responses4.04.55.02.2-2.22.20.3-2.22.22.2-2.2-2.22.2-2.2-2.2-2.2
Condit. Reinf. active-inactive response ratio1.92.02.81.7-1.31.31.0-1.41.51.7-1.7-1.41.2-1.2-1.6-1.4
Condit. Reinf. active responses3.84.65.91.9-2.42.4-0.6-2.32.21.9-1.9-2.32.4-2.4-2.1-2.3
Condit. Reinf. inactive responses1.11.32.10.7-1.31.4-1.2-1.21.10.7-0.7-1.21.5-1.5-0.9-1.3
Incentive salience index mean2.42.83.81.5-1.91.9-0.6-1.81.71.5-1.5-1.81.9-1.9-1.6-1.8
Condit. Reinf. lever presses0.50.63.9-0.2-0.70.8-2.0-0.60.3-0.20.2-0.51.0-0.9-0.0-0.6
Time in familiar zone, hab. session 11.81.72.31.5-1.31.20.7-1.31.41.5-1.5-1.41.1-1.2-1.5-1.4
Time in novel zone, hab. session 10.80.82.0-1.10.6-0.5-1.40.7-0.9-1.21.20.7-0.40.51.00.7
Total zone transitions, hab. session 11.21.72.70.8-1.51.5-1.3-1.41.20.8-0.8-1.41.6-1.6-1.0-1.5
Total locomotion distance, hab. session 11.72.54.90.6-1.81.9-2.2-1.71.30.7-0.7-1.62.0-2.1-1.0-1.8
Locomotion velocity, hab. session 11.92.84.61.0-1.92.0-1.7-1.81.61.0-1.0-1.82.0-2.1-1.3-1.9
Time in familiar zone, hab. session 25.45.77.72.7-2.22.21.6-2.32.52.8-2.8-2.42.0-2.1-2.7-2.4
Time in novel zone, hab. session 23.93.95.7-2.41.8-1.7-1.71.9-2.1-2.42.42.0-1.51.62.31.9
Total zone transitions, hab. session 20.40.53.9-0.8-0.10.2-2.00.0-0.3-0.80.80.10.3-0.40.6-0.1
Total locomotion distance, hab. session 21.11.42.50.7-1.41.4-1.2-1.31.10.7-0.7-1.31.4-1.6-0.9-1.4
Locomotion velocity, hab. session 21.21.62.80.6-1.41.5-1.5-1.31.10.6-0.6-1.31.5-1.7-0.9-1.5
Novel to familiar place preference ratio3.23.35.2-2.31.5-1.4-1.91.6-1.9-2.32.31.7-1.31.32.11.6
Novelty place preference1.91.93.2-1.81.1-1.0-1.71.2-1.4-1.81.81.3-0.90.91.61.2
Time in novel zone, NPP test2.12.23.6-1.91.2-1.2-1.61.3-1.6-1.91.91.4-1.01.01.71.3
Total zone transitions, NPP test0.10.11.0-0.3-0.20.2-1.0-0.1-0.0-0.30.3-0.10.2-0.30.2-0.2
Total locomotion distance, NPP test0.20.32.1-0.5-0.20.3-1.4-0.2-0.1-0.40.4-0.10.3-0.50.3-0.3
Locomotion velocity, NPP test0.20.31.8-0.2-0.50.6-1.3-0.40.2-0.10.1-0.40.6-0.7-0.0-0.5
Pavlov. Cond. lever latency0.20.21.90.40.3-0.41.40.2-0.00.3-0.30.2-0.40.5-0.20.3
Pavlov. Cond. magazine entry latency2.53.23.92.0-1.81.70.7-1.81.92.0-2.0-1.91.7-1.7-2.0-1.8
Pavlov. Cond. change in total contacts0.10.10.10.2-0.30.3-0.1-0.30.30.2-0.2-0.30.3-0.3-0.2-0.3
Pavlov. Cond. index score0.50.60.90.5-0.90.9-0.7-0.80.70.5-0.5-0.81.0-1.0-0.6-0.9
Pavlov. Cond. latency score0.60.71.20.4-1.01.0-1.1-0.90.70.4-0.4-0.81.1-1.1-0.6-0.9
Pavlov. Cond. lever contacts0.40.42.5-0.2-0.60.7-1.6-0.50.3-0.10.1-0.50.8-0.8-0.1-0.6
Pavlov. Cond. magazine entry number0.60.70.8-0.90.9-0.9-0.10.9-0.9-0.90.90.9-0.90.80.90.9
Pavlov. Cond. intertrial magazine entries0.10.21.20.6-0.0-0.01.1-0.10.20.5-0.5-0.1-0.00.1-0.4-0.0
Pavlov. Cond. lever-magazine prob. diff.0.81.01.40.8-1.11.2-0.6-1.11.00.8-0.8-1.11.2-1.2-0.9-1.1
Pavlov. Cond. response bias1.01.21.31.1-1.11.10.1-1.21.21.1-1.1-1.21.1-1.1-1.1-1.2
Bone: apparent density0.71.17.8-0.6-0.80.9-2.8-0.60.2-0.50.5-0.51.1-1.20.2-0.8
Bone surface1.73.015.4-0.3-1.71.8-3.9-1.40.9-0.20.2-1.32.2-2.2-0.3-1.6
Bone volume1.83.015.3-0.3-1.71.8-3.9-1.40.9-0.20.2-1.32.2-2.2-0.3-1.6
Bone: connectivity density0.40.75.1-1.0-0.20.3-2.2-0.0-0.3-0.90.90.00.4-0.60.6-0.2
Bone: cortical apparent density0.91.21.9-1.01.2-1.1-0.11.2-1.2-1.11.11.2-1.01.31.11.4
Bone: cortical area0.50.73.0-1.10.4-0.3-1.70.5-0.7-1.11.10.6-0.10.20.90.5
Bone: cortical porosity0.60.71.00.6-0.91.0-0.5-0.90.80.6-0.6-0.91.0-1.0-0.7-0.9
Bone: cortical porosity0.20.21.4-0.1-0.50.5-1.2-0.40.2-0.10.1-0.30.6-0.6-0.0-0.4
Bone: cortical thickness0.91.62.3-1.51.1-1.1-1.01.2-1.3-1.51.51.2-0.91.01.41.2
Bone: cortical thickness0.10.10.80.30.2-0.20.90.1-0.00.2-0.20.1-0.30.3-0.10.1
Bone: cortical tissue density0.70.91.4-0.81.0-1.0-0.01.0-1.0-0.90.91.0-0.81.10.91.2
Bone: elastic displacement0.30.30.40.5-0.60.6-0.0-0.60.60.5-0.5-0.60.6-0.6-0.6-0.6
Bone: elastic work0.10.20.6-0.60.2-0.2-0.80.3-0.4-0.60.60.3-0.10.20.50.3
Bone: endosteal estimation0.20.41.0-0.80.4-0.3-1.00.4-0.6-0.80.80.5-0.20.30.70.4
Bone: endosteal perimeter0.40.91.60.4-1.11.1-1.2-1.00.80.4-0.4-0.91.3-1.2-0.6-1.0
Bone: final force0.91.52.7-1.60.9-0.9-1.61.0-1.3-1.61.61.1-0.60.71.51.0
Bone: final moment0.71.22.4-1.40.8-0.7-1.50.9-1.1-1.41.41.0-0.50.61.30.9
Bone: marrow area0.20.41.0-0.80.4-0.4-1.00.5-0.6-0.80.80.5-0.20.30.70.5
Bone: maximum diameter0.91.73.20.8-1.51.6-1.5-1.41.20.7-0.8-1.31.8-1.6-1.0-1.4
Bone: maximum force1.01.72.7-1.61.1-1.0-1.41.2-1.4-1.61.61.3-0.80.91.51.2
Bone: maximum moment0.81.42.3-1.51.0-0.9-1.31.1-1.2-1.51.51.1-0.70.81.41.1
Bone: minimum diameter0.10.21.4-0.3-0.30.3-1.2-0.20.0-0.30.3-0.10.5-0.40.1-0.1
Bone: periosteal estimation0.30.73.5-1.10.3-0.2-1.90.4-0.6-1.11.10.50.10.10.90.4
Bone: periosteal perimeter0.30.52.8-0.0-0.70.8-1.7-0.60.4-0.10.0-0.51.0-0.9-0.2-0.6
Bone: post-yield work0.60.81.1-0.80.9-0.9-0.11.0-1.0-0.90.91.0-0.81.00.91.0
Bone: stiffness2.64.25.6-2.31.9-1.9-1.32.0-2.2-2.42.42.1-1.71.72.32.0
Bone: tissue strength1.61.62.0-1.41.2-1.2-0.61.3-1.3-1.41.41.3-1.01.21.41.4
Bone: trabecular number1.21.93.50.6-1.51.6-1.7-1.41.20.7-0.7-1.41.7-1.9-0.9-1.6
Bone: trabecular spacing1.31.76.3-0.11.4-1.52.51.3-0.9-0.20.21.1-1.71.70.51.3
Bone: trabecular thickness1.61.912.9-0.7-1.11.2-3.6-0.90.4-0.60.6-0.71.6-1.60.1-1.0
Bone: trabecular tissue density2.53.55.6-1.42.1-2.10.92.0-1.9-1.51.52.0-2.02.41.72.3
Breakpoint value in progressive ratio session4.75.27.02.6-2.22.21.3-2.32.52.6-2.6-2.32.0-2.0-2.6-2.2
Distance traveled before self-admin0.20.20.3-0.50.3-0.3-0.50.4-0.5-0.60.60.3-0.30.30.50.4
Distance traveled after self-admin0.91.01.31.0-1.11.1-0.1-1.11.11.0-0.9-1.11.0-1.2-1.0-1.2
Delta time in closed arm before/after self-admin1.41.34.0-0.31.3-1.42.01.2-0.9-0.30.31.0-1.61.40.61.1
Delta time in open arm before/after self-admin1.21.11.5-1.21.0-1.0-0.51.1-1.1-1.21.21.1-0.81.11.21.2
Diff in mean of infusions in LGA sessions1.41.61.91.4-1.31.30.4-1.31.41.4-1.4-1.31.1-1.2-1.4-1.3
Extinction: sum of active levers before priming1.11.12.31.4-0.70.71.5-0.81.11.4-1.4-0.90.6-0.5-1.2-0.8
Active lever presses in extinction session 63.13.03.51.8-1.81.80.2-1.81.91.8-1.8-1.81.7-1.8-1.8-1.8
Delta distance traveled before/after self-admin1.51.61.91.3-1.31.30.1-1.31.31.3-1.3-1.31.2-1.3-1.3-1.4
Delta ambulatory time before/after self-admin1.81.92.51.3-1.51.5-0.2-1.51.51.3-1.3-1.51.3-1.6-1.4-1.6
Time in closed arm before self-admin0.70.82.1-1.30.6-0.5-1.40.7-0.9-1.21.20.8-0.30.51.10.7
Time in closed arm after self-admin0.00.00.00.1-0.00.00.1-0.10.10.1-0.1-0.1-0.2-0.2-0.1-0.2
Time in open arm before self-admin1.11.11.51.2-1.01.00.7-1.01.11.2-1.2-1.10.9-1.0-1.2-1.1
Time in open arm after self-admin0.70.81.3-0.81.0-1.00.21.0-0.9-0.80.81.0-0.71.10.91.1
Sum of active levers in priming session hrs 5-60.00.00.10.10.1-0.10.30.1-0.00.0-0.10.1-0.10.2-0.00.1
Time to tail flick, vehicle, before self-admin1.01.02.00.4-1.21.2-1.3-1.10.90.5-0.5-1.21.1-1.4-0.7-1.2
Time to tail flick, vehicle, after self-admin0.20.21.30.40.1-0.11.10.00.20.4-0.4-0.1-0.30.1-0.3-0.1
Time to tail flick, test, before self-admin0.50.51.90.0-0.80.8-1.4-0.70.50.1-0.1-0.70.8-1.0-0.3-0.8
Time to tail flick, test, after self-admin0.30.30.70.3-0.70.7-0.8-0.60.50.3-0.3-0.60.7-0.8-0.4-0.7
Delta time to tail flick, vehicle, before/after SA1.11.02.3-0.41.2-1.21.51.1-0.8-0.40.41.0-1.31.30.61.1
Delta time to tail flick, test, before/after SA0.20.11.00.5-0.0-0.01.0-0.10.20.5-0.5-0.0-0.00.1-0.3-0.0
Ambulatory time before self-admin0.20.20.2-0.40.4-0.4-0.30.4-0.4-0.50.50.4-0.30.40.50.4
Ambulatory time after self-admin0.50.60.70.8-0.80.8-0.0-0.80.80.7-0.7-0.90.7-0.8-0.8-0.8
Total heroin consumption1.92.32.81.5-1.61.60.1-1.61.61.5-1.5-1.71.5-1.6-1.6-1.6
Area under the delay curve1.92.02.7-1.61.3-1.3-0.91.4-1.5-1.61.61.4-1.21.21.61.4
Delay disc. indifference point, 0s delay6.16.610.0-3.12.2-2.1-2.52.4-2.7-3.23.12.5-2.02.02.92.4
Delay disc. indifference point, 16s delay0.10.10.2-0.40.3-0.3-0.30.3-0.4-0.40.40.3-0.20.30.40.3
Delay disc. indifference point, 2s delay5.05.67.6-2.72.2-2.1-1.62.3-2.5-2.72.72.4-2.12.02.62.3
Delay disc. indifference point, 24s delay0.50.50.6-0.80.7-0.7-0.00.7-0.7-0.70.70.7-0.80.60.70.6
Delay disc. indifference point, 4s delay0.90.91.8-1.30.7-0.6-1.40.8-1.0-1.31.30.8-0.60.51.10.7
Delay disc. indifference point, 8s delay1.11.21.5-1.01.2-1.20.31.2-1.1-1.01.01.2-1.21.21.11.2
Delay discount exponential model param1.71.82.41.5-1.31.20.7-1.31.41.5-1.5-1.41.2-1.2-1.5-1.3
Delay discount hyperbolic model param2.42.63.41.9-1.51.50.9-1.61.71.8-1.9-1.61.4-1.4-1.8-1.6
Fecal boli incidents, locomotor time 12.22.43.6-1.21.7-1.70.71.7-1.5-1.31.21.7-1.71.91.41.8
Change in fecal boli incidents, locomotor task0.70.71.60.3-0.91.0-1.3-0.90.70.3-0.3-0.81.0-1.1-0.5-0.9
Time >=10cm from walls, locomotor time 10.30.31.2-0.60.2-0.2-1.10.3-0.4-0.70.70.3-0.10.10.60.3
Bouts of movement, locomotor time 10.10.10.30.5-0.30.30.3-0.40.40.5-0.5-0.40.3-0.3-0.4-0.3
Total resting periods, locomotor time 10.20.20.30.6-0.50.50.1-0.50.50.5-0.5-0.50.5-0.4-0.5-0.4
Rest time, locomotor task time 10.20.20.30.5-0.50.5-0.2-0.50.50.4-0.4-0.60.5-0.5-0.4-0.5
Distance moved, locomotor task time 10.40.41.6-0.90.3-0.2-1.30.4-0.5-0.80.80.5-0.10.10.70.3
Vertical activity count, locomotor time 10.10.10.1-0.20.3-0.30.30.3-0.3-0.20.20.3-0.30.30.20.3
Time >=10cm from walls, locomotor time 21.11.21.6-0.81.2-1.20.41.2-1.1-0.90.91.1-1.21.31.01.2
Bouts of movement, locomotor time 20.60.71.10.4-0.91.0-1.0-0.90.70.4-0.4-0.81.0-1.0-0.6-0.9
Total resting periods, locomotor time 20.60.61.20.4-0.91.0-1.1-0.90.70.4-0.3-0.81.0-1.1-0.5-0.9
Rest time, locomotor task time 20.60.71.00.7-1.01.0-0.6-0.90.80.6-0.6-0.91.0-1.0-0.7-0.9
Distance moved, locomotor task time 20.91.01.5-0.81.2-1.20.61.1-1.0-0.80.81.1-1.11.20.91.1
Vertical activity count, locomotor time 21.11.22.0-0.51.2-1.31.21.2-1.0-0.60.61.1-1.31.40.81.2
Weight adjusted by age0.40.51.1-0.40.8-0.80.80.8-0.6-0.40.40.7-1.00.80.50.7
Seeking ratio, delayed vs. immediate footshock5.15.87.12.2-2.62.6-0.2-2.62.52.3-2.3-2.62.6-2.7-2.4-2.7
Locomotion in novel chamber0.40.50.80.8-0.60.50.8-0.60.70.9-0.8-0.80.3-0.7-0.8-0.8
Locomotion in novel chamber post-restriction0.70.91.11.0-0.90.90.2-0.91.00.9-1.0-1.00.9-1.0-1.0-1.1
Progressive ratio0.20.30.8-0.40.6-0.60.60.6-0.5-0.30.30.5-0.90.50.40.5
Food seeking constrained by brief footshock0.10.10.20.3-0.30.30.0-0.30.30.3-0.3-0.40.2-0.5-0.3-0.5
Seeking ratio, punishment vs. effort0.10.20.40.3-0.40.5-0.3-0.40.40.3-0.3-0.40.7-0.4-0.3-0.4
Run reversals in cocaine runway, females0.80.81.70.5-1.01.0-0.7-1.00.90.6-0.6-1.00.8-1.3-0.7-1.2
Run reversals in cocaine runway, males1.51.42.41.0-1.31.3-0.5-1.31.21.0-1.0-1.31.3-1.6-1.1-1.5
Latency to leave start box in cocaine runway1.41.62.90.9-1.41.5-1.2-1.41.20.8-0.8-1.31.7-1.4-1.0-1.2
Latency to leave start box in cocaine runway, F0.60.64.4-0.2-0.70.8-2.1-0.50.2-0.30.3-0.51.0-0.90.0-0.5
Latency to leave start box in cocaine runway, M2.52.43.81.9-1.31.31.5-1.41.61.9-1.9-1.51.2-1.0-1.8-1.3
Cd content in liver0.20.20.2-0.50.4-0.4-0.30.4-0.4-0.50.50.4-0.30.30.50.4
Co content in liver0.50.60.90.9-0.70.60.7-0.70.80.9-0.9-0.70.7-0.7-0.9-0.8
Cu content in liver0.20.21.6-0.5-0.10.2-1.3-0.0-0.2-0.50.50.00.3-0.20.3-0.0
Fe content in liver0.00.10.50.20.1-0.10.70.10.00.2-0.20.0-0.20.2-0.10.1
K content in liver0.20.21.3-0.2-0.40.4-1.1-0.30.1-0.20.2-0.20.5-0.70.0-0.4
Mg content in liver0.30.32.0-0.2-0.50.5-1.4-0.40.2-0.20.2-0.30.6-0.80.0-0.5
Mn content in liver2.02.35.60.5-1.71.8-2.4-1.61.20.5-0.5-1.52.0-2.0-0.9-1.7
Na content in liver0.80.91.4-1.20.8-0.7-1.00.8-1.0-1.21.20.9-0.50.61.10.8
Rb content in liver0.40.52.6-0.90.2-0.1-1.60.3-0.5-0.90.90.30.0-0.00.70.3
Se content in liver0.20.20.40.4-0.50.5-0.2-0.50.50.4-0.4-0.50.5-0.7-0.4-0.6
Sr content in liver0.20.21.60.30.3-0.41.30.3-0.10.3-0.30.2-0.40.4-0.10.2
Zn content in liver1.82.05.01.9-0.90.82.2-1.01.31.9-1.8-1.20.6-0.8-1.6-1.1