Hub : Genes

Fads1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000020480 0.13 0.06 1.6e-08 0.03 0.06 0.06 0.05 6.9e-04 7.7e-07 1.0e-06 2.0e-06
2 BLA gene expression ENSRNOG00000020480 0.63 0.13 0.0e+00 0.36 0.36 0.36 0.37 4.5e-20 2.1e-20 1.6e-20 8.5e-21
3 Brain gene expression ENSRNOG00000020480 0.77 0.05 0.0e+00 0.48 0.55 0.56 0.55 1.1e-49 2.6e-61 2.1e-62 3.8e-61
4 Eye gene expression ENSRNOG00000020480 0.66 0.15 1.1e-03 0.06 0.04 0.01 0.1 4.5e-02 7.4e-02 1.9e-01 1.4e-02
5 IL gene expression ENSRNOG00000020480 0.66 0.16 4.3e-08 0.28 0.03 0.23 0.01 2.2e-07 5.5e-02 3.1e-06 2.1e-01
6 LHb gene expression ENSRNOG00000020480 0.35 0.21 5.6e-03 0.05 0 0.19 0 2.7e-02 2.9e-01 3.2e-05 2.8e-01
7 Liver gene expression ENSRNOG00000020480 0.16 0.08 5.8e-10 0.06 0.07 0.07 0.07 1.8e-07 1.2e-08 2.9e-08 5.3e-08
8 Liver isoform ratio ENSRNOT00000027834 0.05 0.04 1.0e-03 0.01 0.02 0.01 0.01 2.4e-02 6.6e-03 2.0e-02 3.3e-02
9 Liver isoform ratio ENSRNOT00000112242 0.06 0.04 5.5e-04 0.01 0.02 0.01 0.01 2.0e-02 5.0e-03 1.2e-02 5.1e-02
10 Liver mRNA stability ENSRNOG00000020480 0.05 0.04 6.3e-03 0.01 0.01 0.01 0.01 2.1e-02 1.4e-02 1.4e-02 1.6e-02
11 NAcc gene expression ENSRNOG00000020480 0.54 0.13 0.0e+00 0.28 0.3 0.31 0.3 2.9e-21 1.3e-22 2.9e-23 7.8e-23
12 NAcc intron excision ratio chr1:206832109:206837056 0.04 0.03 3.3e-03 0.01 0.01 0 0 3.1e-02 3.2e-02 3.0e-01 1.9e-01
13 NAcc intron excision ratio chr1:206837116:206838685 0.04 0.03 4.3e-03 0 0.01 -0 0 1.2e-01 7.8e-02 8.6e-01 3.2e-01
14 OFC gene expression ENSRNOG00000020480 0.75 0.14 8.6e-09 0.22 0.02 0.22 0.05 7.6e-06 1.2e-01 4.6e-06 2.0e-02
15 PL gene expression ENSRNOG00000020480 0.76 0.11 0.0e+00 0.37 0.41 0.39 0.39 9.3e-30 1.2e-33 3.1e-31 1.4e-31

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail1.75.416.13.22.02.63.21.24.03.9-0.60.82.71.81.10.80.41.8
BMI without tail0.30.62.60.80.40.61.0-0.11.61.30.4-0.30.50.2-0.31.0-0.30.3
Body weight0.62.79.82.10.20.62.4-0.83.13.00.8-0.61.7-0.2-0.42.4-0.6-0.2
Epididymis fat weight1.63.75.62.02.01.91.92.01.21.6-2.32.42.12.11.9-1.91.51.9
Glucose2.53.88.01.32.11.90.62.40.40.7-2.52.41.22.22.8-2.61.22.3
Heart weight0.81.12.30.71.11.00.41.10.50.6-1.51.50.71.11.3-1.30.91.2
Left kidney weight0.51.63.21.60.90.91.60.81.21.6-1.41.51.81.01.5-0.70.80.8
Right kidney weight0.41.12.11.40.80.81.40.61.21.4-0.91.01.50.81.2-0.40.60.7
Tail length0.92.94.7-1.3-1.9-1.9-0.9-2.2-0.5-0.81.9-1.8-1.3-2.0-2.22.2-1.2-2.0
Length with tail0.41.45.00.5-1.1-0.90.9-1.61.11.11.2-1.10.5-1.3-1.22.2-0.7-1.4
Length without tail0.30.72.41.20.00.11.2-0.41.41.50.2-0.11.2-0.10.11.0-0.1-0.3
Liver weight, left0.10.20.5-0.20.2-0.1-0.60.3-0.4-0.5-0.50.5-0.20.20.4-0.7-0.10.2
Liver weight, right0.30.41.00.61.00.90.00.90.70.5-0.40.40.30.90.7-0.50.11.0
Parametrial fat weight3.26.311.02.32.42.32.22.61.21.7-3.13.12.72.63.3-2.82.12.3
Retroperitoneal fat weight2.68.717.52.42.92.51.73.10.71.6-4.24.22.83.13.8-3.92.22.7
Intraocular pressure0.40.61.1-1.0-0.8-0.8-0.7-0.6-1.1-1.00.6-0.6-0.9-0.8-0.60.3-0.3-0.6
Extensor digitorum longus weight1.04.114.81.2-1.0-0.32.0-2.02.72.62.4-2.10.9-1.4-2.23.8-1.4-1.5
Soleus weight0.61.86.5-0.01.20.9-0.71.8-0.9-0.9-1.81.70.11.41.5-2.51.11.4
Tibialis anterior weight2.79.430.0-0.2-2.7-2.10.3-3.81.71.44.2-4.0-0.8-3.2-3.75.5-3.3-3.3
Tibia length0.20.71.91.0-0.2-0.11.4-0.61.31.30.6-0.51.0-0.3-0.11.2-0.1-0.6
Number of licking bursts0.10.10.30.30.10.00.50.10.00.3-0.40.40.50.10.3-0.20.1-0.1
Food consumed during 24 hour testing period0.10.10.4-0.40.0-0.1-0.60.2-0.3-0.70.1-0.1-0.40.10.0-0.30.20.1
Times rat made contact with spout0.80.91.6-1.1-0.9-0.9-1.0-0.9-0.7-0.91.1-1.1-1.2-1.0-1.30.9-0.7-0.8
Mean time between licks in bursts0.40.51.9-0.5-0.4-0.3-0.4-0.70.1-0.11.0-0.9-0.8-0.6-1.41.1-0.7-0.5
Mean num. licks in bursts0.81.02.1-1.2-0.7-0.7-1.4-0.6-0.8-1.21.1-1.1-1.5-0.8-1.20.6-0.6-0.5
Std. dev. time between licks in bursts0.10.10.20.00.50.4-0.30.50.1-0.1-0.40.4-0.00.40.2-0.40.10.4
Water consumed over 24 hours0.30.30.8-0.5-0.7-0.7-0.1-0.7-0.3-0.40.6-0.6-0.3-0.7-0.90.7-0.1-0.7
Indifference point 0 sec0.10.20.60.1-0.5-0.40.1-0.70.40.30.5-0.50.0-0.5-0.60.8-0.5-0.6
Indifference point AUC0.60.81.9-0.2-1.0-0.80.1-1.10.40.11.2-1.2-0.3-1.0-0.71.4-0.7-1.0
Indifference point function ln k2.53.56.21.02.22.10.72.50.50.6-2.42.31.12.31.5-2.51.62.5
Indifference point function log k2.53.56.21.02.22.10.72.50.50.6-2.42.31.12.31.5-2.51.62.5
Delay discounting total patch changes 0 sec0.30.40.9-0.2-0.7-0.7-0.3-0.90.1-0.00.7-0.7-0.3-0.7-0.90.9-0.6-0.8
Delay discounting total patch changes 12 sec3.14.19.8-0.8-2.2-2.0-0.3-2.70.3-0.02.6-2.5-0.9-2.4-2.33.1-1.7-2.5
Delay discounting total patch changes 18 sec0.50.71.1-0.6-1.0-0.9-0.6-1.0-0.1-0.41.1-1.1-0.7-1.0-0.71.0-0.8-0.9
Delay discounting total patch changes 24 sec1.31.75.80.6-1.0-0.71.0-1.71.41.41.4-1.30.5-1.2-1.42.4-0.9-1.4
Delay discounting total patch changes 6 sec0.20.30.80.4-0.4-0.30.5-0.60.90.60.4-0.30.4-0.4-0.40.8-0.3-0.6
Delay discounting time to switch 0 sec0.50.81.81.20.70.81.30.61.31.2-0.40.41.10.70.9-0.00.40.6
Delay discounting water rate 0 sec0.20.31.0-0.7-0.3-0.4-0.9-0.1-1.0-1.0-0.0-0.0-0.6-0.2-0.4-0.40.0-0.2
Delay discounting water rate 12 sec0.30.51.6-0.20.70.6-0.40.9-0.6-0.5-0.90.9-0.20.80.2-1.30.40.9
Delay discounting water rate 18 sec0.40.50.90.30.80.7-0.10.90.1-0.0-1.01.00.30.90.2-0.90.70.9
Delay discounting water rate 24 sec0.20.31.0-0.40.30.2-0.40.6-0.8-0.8-0.70.6-0.30.50.0-1.00.50.5
Delay discounting water rate 6 sec0.20.30.7-0.40.30.1-0.70.4-0.8-0.7-0.60.6-0.40.3-0.2-0.80.60.4
Locomotor activity0.30.42.1-0.8-0.2-0.4-1.4-0.0-0.9-0.9-0.10.1-1.0-0.20.4-0.4-0.6-0.1
Locomotor testing distance0.20.31.4-0.40.30.1-1.20.4-0.3-0.5-0.40.4-0.70.30.6-0.7-0.60.5
Locomotor testing rearing0.20.31.1-0.50.40.3-1.10.6-0.4-0.8-0.20.1-0.80.40.3-0.7-0.00.7
Light reinforcement 10.10.10.5-0.3-0.0-0.2-0.70.2-0.2-0.60.2-0.2-0.4-0.00.2-0.3-0.30.2
Light reinforcement 21.11.42.81.21.10.91.21.20.70.8-1.31.31.51.21.7-1.31.21.1
Reaction time number correct0.30.40.9-0.6-0.5-0.5-0.7-0.6-0.1-0.51.0-0.9-0.8-0.6-0.80.9-0.3-0.4
Reaction time mean minus median0.60.81.4-0.7-1.1-1.0-0.4-1.1-0.6-0.61.2-1.2-0.8-1.1-0.81.0-0.8-1.0
Reaction time mean minus median AUC1.72.22.9-1.6-1.6-1.5-1.3-1.5-1.3-1.41.7-1.7-1.6-1.6-1.31.2-1.3-1.4
Reaction time num false alarms0.40.51.5-1.0-0.7-0.8-1.2-0.6-0.9-1.00.2-0.2-0.9-0.6-0.70.2-0.3-0.6
Reaction time num false alarms AUC1.01.42.2-1.3-1.3-1.4-1.5-1.3-1.0-1.20.8-0.8-1.3-1.3-1.30.8-0.7-1.2
Reaction time trials correct on left0.30.40.9-0.6-0.5-0.5-0.7-0.6-0.1-0.51.0-0.9-0.8-0.6-0.80.9-0.3-0.4
Reaction time trials on left0.40.61.1-0.7-0.6-0.6-0.8-0.7-0.2-0.61.1-1.1-0.9-0.7-0.91.0-0.4-0.5
Reaction time mean0.20.20.7-0.6-0.4-0.3-0.3-0.3-0.5-0.50.8-0.8-0.6-0.4-0.50.3-0.4-0.3
Reaction time mean AUC0.10.10.4-0.4-0.1-0.0-0.20.0-0.4-0.50.5-0.6-0.5-0.1-0.40.1-0.10.0
Median of all reaction times0.00.00.2-0.00.00.10.30.00.0-0.00.5-0.5-0.1-0.0-0.40.2-0.00.1
Reaction time omissions1.01.41.9-1.3-1.3-1.4-1.1-1.3-1.0-1.21.1-1.1-1.2-1.3-1.30.9-0.6-1.3
Reaction time false alarm rate0.10.20.4-0.5-0.5-0.6-0.6-0.5-0.6-0.5-0.10.1-0.4-0.5-0.4-0.0-0.2-0.5
Reaction time premature initiation rate0.81.13.81.50.30.41.8-0.31.91.90.10.01.50.2-0.21.20.2-0.1
Reaction time premature initiations0.70.93.80.6-0.5-0.40.9-1.01.41.11.1-1.00.5-0.7-1.11.9-0.3-0.8
Std. dev. reaction times1.01.42.0-1.4-1.3-1.2-1.1-1.1-1.4-1.41.2-1.3-1.4-1.2-1.10.7-0.8-1.1
Reaction time trials completed0.40.61.1-0.7-0.6-0.6-0.8-0.7-0.2-0.61.1-1.1-0.9-0.7-0.91.0-0.4-0.5
Reaction time trials AUC0.20.40.8-0.5-0.4-0.4-0.8-0.5-0.1-0.50.9-0.9-0.8-0.5-0.70.8-0.3-0.3
Social response proportion0.10.10.30.20.20.00.00.20.60.1-0.20.20.30.2-0.1-0.10.40.1
Social responses0.60.81.4-1.0-0.9-1.2-1.2-0.8-0.7-1.10.7-0.8-0.9-0.9-1.10.6-0.4-1.0
Social time1.41.83.2-1.7-1.2-1.3-1.6-1.1-1.2-1.61.3-1.3-1.8-1.3-1.70.9-0.8-1.1
Conditioned locomotion0.20.20.60.0-0.4-0.30.0-0.60.30.30.5-0.5-0.1-0.5-0.70.8-0.7-0.6
Cocaine response after cond. corrected0.20.20.70.00.70.8-0.30.70.20.1-0.30.3-0.30.60.0-0.5-0.10.9
Cocaine response after cond. not corrected0.30.31.10.20.81.0-0.10.90.40.2-0.30.3-0.10.80.4-0.60.11.1
Cocaine response before conditioning0.10.10.30.1-0.1-0.10.3-0.00.0-0.10.5-0.50.2-0.10.40.20.4-0.1
Saline control response1.01.33.4-0.5-1.1-0.9-0.4-1.30.2-0.11.6-1.6-0.7-1.2-1.61.8-1.0-1.2
Condit. Reinf. active minus inactive responses0.00.10.2-0.10.20.3-0.10.4-0.3-0.30.0-0.1-0.20.20.2-0.4-0.10.4
Condit. Reinf. active-inactive response ratio0.70.81.60.80.81.01.31.00.30.8-0.90.80.90.90.8-0.90.61.0
Condit. Reinf. active responses0.00.00.1-0.10.10.2-0.10.20.1-0.20.3-0.3-0.20.1-0.2-0.00.00.3
Condit. Reinf. inactive responses0.20.21.1-0.5-0.2-0.3-1.1-0.1-0.0-0.70.6-0.6-0.7-0.2-0.40.20.0-0.1
Condit. Reinf. lever presses0.20.31.10.70.20.41.00.10.90.80.3-0.20.70.20.30.40.30.2
Condit. Reinf. lever reinforcers received0.10.10.5-0.2-0.2-0.1-0.1-0.10.0-0.20.6-0.7-0.3-0.2-0.50.4-0.2-0.0
Pavlov. Cond. lever latency0.60.82.4-1.1-0.8-1.1-1.5-0.7-1.2-1.20.2-0.2-1.0-0.8-0.9-0.0-0.7-0.9
Pavlov. Cond. magazine entry latency1.01.24.30.1-0.7-0.31.1-1.01.00.71.8-1.80.0-0.9-1.02.1-0.3-0.7
Pavlov. Cond. change in total contacts0.30.41.60.60.20.41.30.01.00.70.8-0.80.50.1-0.00.80.50.2
Pavlov. Cond. index score0.60.73.10.80.10.51.8-0.21.31.20.9-0.90.8-0.00.01.20.40.1
Pavlov. Cond. latency score0.60.83.51.00.30.61.90.01.41.30.7-0.71.00.20.21.00.50.3
Pavlov. Cond. lever contacts0.10.10.50.10.10.40.70.10.50.30.7-0.70.00.00.00.50.10.3
Pavlov. Cond. magazine entry number1.51.86.7-0.30.80.3-1.61.3-1.4-1.1-2.12.0-0.21.01.2-2.60.40.9
Pavlov. Cond. intertrial magazine entries0.30.41.4-0.30.2-0.1-0.90.5-0.9-0.7-0.80.7-0.30.30.7-1.20.00.3
Pavlov. Cond. lever-magazine prob. diff.0.60.82.80.7-0.00.41.7-0.31.31.11.1-1.10.7-0.1-0.11.30.30.0
Pavlov. Cond. response bias0.30.41.30.3-0.10.31.0-0.20.90.71.1-1.10.2-0.2-0.31.10.00.0
Conditioned reinforcement - actives0.30.31.1-0.40.40.4-0.50.8-0.6-0.8-0.40.3-0.40.60.0-1.00.50.8
Conditioned reinforcement - inactives1.11.22.00.91.21.30.81.40.70.6-1.11.11.01.41.0-1.30.91.4
Conditioned locomotion1.82.23.81.21.71.60.71.90.80.7-1.71.71.21.81.3-1.81.21.9
Intermittent access intake day 1-15 change0.40.41.6-0.9-0.3-0.5-1.00.0-1.1-1.30.2-0.3-0.8-0.2-0.3-0.50.0-0.2
Intermittent access intake escalation0.30.31.1-0.8-0.2-0.4-0.80.0-0.9-1.00.3-0.3-0.7-0.2-0.4-0.30.1-0.2
Intermittent access intake escalation 20.50.50.8-0.8-0.7-0.7-0.5-0.6-0.8-0.90.8-0.8-0.7-0.7-0.70.4-0.1-0.8
Intermitt. access day 1 inactive lever presses2.93.14.51.61.91.91.42.11.21.3-1.91.91.62.02.1-1.81.32.1
Intermitt. access day 15 inactive lever presses3.33.75.32.32.02.12.11.92.32.2-1.51.62.32.01.7-1.11.12.0
Intermitt. access escalation Index1.11.02.21.11.01.00.61.00.60.9-1.31.31.11.11.5-1.00.50.8
Intermittent access day 1 total infusions6.37.19.12.92.93.02.52.92.52.6-2.72.72.93.02.4-2.11.52.9
Intermittent access day 15 total infusions3.03.35.91.42.12.00.92.40.90.8-2.12.11.52.21.7-2.31.42.2
Intermittent access terminal intake (last 3 days)2.12.33.31.51.71.81.41.81.31.2-1.41.41.61.81.2-1.41.21.7
Intermittent access total infusions3.23.54.91.92.12.11.62.21.61.6-1.91.91.92.21.8-1.71.22.1
Intermittent access day 1 locomotion5.75.97.82.82.62.72.42.42.62.7-2.22.32.72.62.1-1.51.42.6
Intermittent access day 15 total locomotion2.62.73.71.91.81.91.91.81.81.8-1.31.41.81.81.2-1.01.01.9
Intermittent access total locomotion7.38.311.13.33.13.23.13.03.03.1-2.52.53.33.12.6-1.81.83.1
Intermittent access standard deviation0.80.92.3-1.4-0.5-0.5-1.0-0.2-1.2-1.50.7-0.8-1.4-0.5-1.5-0.0-0.0-0.2
Cocaine induced anxiety0.10.10.4-0.2-0.3-0.10.1-0.30.10.00.6-0.6-0.3-0.3-0.20.6-0.1-0.2
Post-drug Anxiety0.20.20.7-0.1-0.2-0.00.2-0.30.40.20.8-0.8-0.2-0.3-0.50.8-0.2-0.1
Baseline Anxiety0.30.31.1-0.1-0.4-0.40.0-0.60.40.20.8-0.7-0.2-0.5-1.11.0-0.5-0.4
Lifetime Intake2.73.04.31.72.02.11.42.11.51.5-1.81.81.72.11.4-1.61.12.1
Incentive Sensitization - Responses0.60.61.01.00.80.80.80.70.90.9-0.60.61.00.80.9-0.40.50.7
Incentive Sensitization - Breakpoint1.11.11.61.31.11.11.01.01.11.1-0.90.91.31.11.2-0.70.71.0
Progressive ratio test 1 active lever presses0.60.61.60.40.80.70.01.1-0.10.0-1.11.00.50.90.7-1.30.50.9
Progressive ratio test 1 breakpoint0.40.41.40.20.60.5-0.20.9-0.3-0.2-0.90.90.30.80.6-1.20.50.7
Progressive ratio test 1 inactive lever presses0.80.91.91.20.91.01.20.71.31.4-0.60.61.10.80.5-0.10.30.9
Progressive ratio test 2 active lever presses1.71.83.11.11.51.50.71.80.80.7-1.51.51.21.61.3-1.61.01.6
Progressive ratio test 2 breakpoint1.51.73.50.91.41.30.41.70.30.4-1.61.61.01.61.5-1.90.91.5
Progressive ratio test 2 inactive lever presses2.73.14.41.82.02.01.62.01.81.6-1.61.71.82.11.4-1.51.22.1
Total sessions with >9 infusions2.22.43.71.41.71.81.11.91.01.2-1.81.81.41.91.4-1.70.91.9
Short access day 1 total inactive lever presses1.61.82.51.21.41.40.91.50.81.0-1.61.61.31.51.3-1.41.01.5
Short access day 10 total inactive lever presses0.60.71.90.10.90.8-0.31.1-0.1-0.1-1.21.10.11.00.9-1.40.61.1
Short access day 1 total infusions0.90.91.60.71.21.20.61.20.60.6-1.11.10.71.20.7-1.10.61.3
Short access day 10 total infusions5.15.77.72.72.62.82.32.52.42.5-2.22.32.62.62.0-1.71.32.6
Short access total infusions2.12.43.61.61.81.91.31.81.61.5-1.51.51.51.81.0-1.20.91.9
Short access day 1 locomotion0.80.81.71.20.91.11.20.71.11.3-0.70.71.10.90.3-0.20.50.8
Short access day 10 total locomotion3.23.44.92.22.02.22.21.92.02.2-1.51.62.12.01.5-1.00.92.1
Short access total locomotion3.13.25.72.21.92.02.21.62.32.4-1.31.42.11.81.1-0.60.91.9
Compulsive drug intake3.02.94.1-1.8-1.8-1.8-1.6-1.9-1.2-1.31.8-1.8-1.9-1.9-2.01.8-1.2-1.7
One hour access (0.3 mA shock)2.63.05.71.21.91.80.82.30.60.6-2.12.11.32.11.8-2.41.32.1
One hour access (shock baseline)2.73.17.01.11.81.70.82.30.30.3-2.22.21.42.12.2-2.61.41.9
Number of responses in last shaping day0.10.20.5-0.4-0.3-0.3-0.3-0.4-0.2-0.20.4-0.4-0.5-0.4-0.70.5-0.1-0.3
Context. condit. distance diff. score0.20.20.40.20.50.60.40.50.30.3-0.40.40.30.5-0.1-0.40.60.6
Locomotion velocity, session 10.10.10.3-0.10.30.4-0.40.20.4-0.00.5-0.5-0.50.1-0.30.3-0.40.4
Locomotion distance, session 10.20.31.30.40.40.6-0.00.11.10.70.6-0.6-0.10.2-0.40.8-0.40.4
Locomotion velocity, session 20.50.62.00.6-0.20.10.8-0.61.21.10.9-0.80.4-0.4-0.61.4-0.5-0.4
Locomotion distance, session 20.20.30.8-0.2-0.20.0-0.2-0.40.40.30.7-0.7-0.6-0.3-0.60.9-0.9-0.2
Locomotion velocity, session 32.12.44.61.91.61.72.11.21.92.1-1.21.31.91.50.9-0.51.01.4
Locomotion distance, session 30.10.10.20.40.40.30.20.30.40.2-0.40.40.50.40.0-0.30.40.3
Stereotopy head waving bouts, day 31.41.72.71.51.51.61.21.21.51.7-1.21.31.21.41.1-0.70.51.5
Stereotopy head waving duration, day 30.60.71.41.00.80.91.10.60.91.2-0.90.90.90.80.7-0.40.30.8
Locomotion velocity, session 70.30.30.70.70.40.30.80.30.40.7-0.80.80.80.40.5-0.40.30.1
Locomotion distance, session 70.20.30.60.60.60.50.50.50.50.6-0.80.80.50.60.2-0.50.30.5
Stereotopy head waving bouts, day 70.10.10.40.50.10.30.70.00.50.60.00.00.50.10.20.2-0.10.1
Stereotopy head waving duration, day 70.30.41.30.5-0.4-0.30.7-0.70.80.80.7-0.60.4-0.5-0.21.2-0.4-0.6
Locomotion velocity, session 80.40.40.6-0.7-0.7-0.8-0.7-0.7-0.5-0.70.5-0.5-0.7-0.7-0.80.5-0.6-0.7
Locomotion distance, session 80.30.50.90.70.91.00.60.70.70.8-0.60.60.50.80.5-0.50.30.9
Degree of sensitization distance1.01.01.81.11.11.31.20.91.21.4-0.80.90.91.00.8-0.50.31.1
Degree of sensitization stereotypy0.20.20.70.2-0.4-0.20.6-0.60.50.40.7-0.70.2-0.4-0.20.9-0.3-0.4
Condit. Reinf. active minus inactive responses0.30.31.2-0.1-0.10.2-0.1-0.30.70.31.1-1.1-0.5-0.2-0.61.0-0.50.1
Condit. Reinf. active-inactive response ratio1.01.12.6-1.0-0.8-0.5-1.0-0.8-0.3-0.71.6-1.6-1.4-0.9-1.11.2-1.0-0.5
Condit. Reinf. active responses0.30.41.50.70.50.80.70.31.20.90.5-0.50.30.4-0.00.6-0.10.6
Condit. Reinf. inactive responses1.31.52.31.41.41.41.51.21.21.3-1.01.01.41.31.0-0.81.01.2
Incentive salience index mean0.30.41.70.70.50.70.50.31.30.90.5-0.40.30.4-0.10.6-0.00.5
Condit. Reinf. lever presses0.71.02.21.41.01.01.10.81.51.3-0.50.61.30.90.6-0.20.70.8
Time in familiar zone, hab. session 10.10.10.20.30.40.40.40.30.40.3-0.00.00.30.30.1-0.00.40.3
Time in novel zone, hab. session 10.30.20.7-0.50.10.0-0.80.3-0.8-0.8-0.40.3-0.50.20.3-0.80.20.3
Total zone transitions, hab. session 10.50.71.0-0.6-0.8-0.8-0.9-0.9-0.3-0.41.0-1.0-0.8-0.9-0.91.0-0.9-1.0
Total locomotion distance, hab. session 10.30.51.00.70.91.00.50.80.80.8-0.50.50.60.80.7-0.40.30.8
Locomotion velocity, hab. session 10.10.10.40.40.30.40.20.10.60.60.2-0.10.20.10.00.3-0.30.1
Time in familiar zone, hab. session 20.30.31.1-0.8-0.3-0.4-0.8-0.0-0.8-1.00.1-0.2-0.7-0.20.0-0.4-0.0-0.1
Time in novel zone, hab. session 20.20.20.90.70.40.50.70.11.00.90.1-0.00.50.30.10.5-0.00.3
Total zone transitions, hab. session 20.30.31.00.10.00.2-0.5-0.31.00.40.9-0.9-0.3-0.1-0.71.0-0.6-0.1
Total locomotion distance, hab. session 20.20.30.90.50.80.90.10.61.00.60.0-0.00.10.60.20.10.10.8
Locomotion velocity, hab. session 20.40.51.20.71.01.10.40.81.10.8-0.30.30.40.90.5-0.20.30.9
Novel to familiar place preference ratio0.40.41.20.5-0.5-0.40.7-0.80.60.90.4-0.30.5-0.5-0.21.1-0.4-0.7
Novelty place preference0.30.30.70.4-0.4-0.30.8-0.70.40.70.2-0.10.5-0.4-0.00.8-0.2-0.6
Time in novel zone, NPP test0.30.30.80.4-0.3-0.20.8-0.70.50.80.3-0.20.5-0.4-0.10.9-0.3-0.5
Total zone transitions, NPP test0.71.12.5-0.5-0.8-0.7-0.9-1.10.2-0.11.5-1.5-0.9-1.0-1.21.6-1.2-0.9
Total locomotion distance, NPP test0.10.10.20.00.10.2-0.5-0.00.40.20.3-0.3-0.30.0-0.10.4-0.50.1
Locomotion velocity, NPP test0.10.10.5-0.2-0.1-0.1-0.7-0.20.1-0.10.3-0.3-0.4-0.2-0.10.3-0.5-0.2
Pavlov. Cond. lever latency0.30.41.9-1.0-0.6-0.6-0.5-0.3-1.4-1.0-0.10.0-0.8-0.5-0.2-0.3-0.2-0.4
Pavlov. Cond. magazine entry latency0.40.51.41.10.50.61.10.31.21.10.0-0.01.00.40.30.30.40.3
Pavlov. Cond. change in total contacts0.10.10.30.50.30.30.30.20.60.40.2-0.20.40.20.20.10.20.2
Pavlov. Cond. index score0.10.10.30.40.10.10.20.00.60.40.3-0.30.40.1-0.00.40.1-0.0
Pavlov. Cond. latency score0.10.20.70.60.40.40.20.30.80.60.1-0.00.50.40.10.10.30.3
Pavlov. Cond. lever contacts0.20.20.70.70.60.50.30.50.80.6-0.20.30.60.50.4-0.10.30.4
Pavlov. Cond. magazine entry number0.20.20.60.00.40.4-0.00.5-0.1-0.1-0.80.8-0.00.50.5-0.70.10.6
Pavlov. Cond. intertrial magazine entries0.70.91.6-0.9-1.0-1.0-1.3-0.9-0.8-0.90.9-0.9-1.0-1.0-0.30.6-1.0-0.9
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.3-0.00.00.2-0.10.50.40.5-0.40.3-0.1-0.10.5-0.1-0.2
Pavlov. Cond. response bias0.10.10.30.40.00.10.4-0.10.50.50.4-0.40.4-0.00.10.50.1-0.1
Bone: apparent density0.40.61.21.10.70.70.90.61.11.0-0.60.61.10.80.8-0.30.60.6
Bone surface0.50.92.81.50.50.61.30.21.71.6-0.20.31.50.50.80.40.60.3
Bone volume0.61.02.31.40.80.81.30.61.31.3-0.60.61.50.80.9-0.20.90.6
Bone: connectivity density0.40.62.51.20.50.61.00.11.61.40.00.01.00.40.30.60.20.3
Bone: cortical apparent density0.70.91.3-0.7-1.1-1.0-0.4-1.1-0.4-0.51.2-1.1-0.7-1.1-1.11.1-0.8-1.1
Bone: cortical area0.10.10.60.50.00.00.5-0.10.80.50.3-0.30.50.00.20.50.1-0.1
Bone: cortical porosity0.70.71.0-1.0-1.0-1.0-0.9-0.9-0.9-0.90.7-0.7-0.9-0.9-1.00.6-0.6-1.0
Bone: cortical porosity1.21.31.9-1.1-1.3-1.3-1.1-1.2-1.0-0.91.1-1.1-1.1-1.3-1.41.0-0.9-1.3
Bone: cortical thickness2.23.76.6-1.3-2.0-2.0-1.2-2.3-0.3-0.82.5-2.5-1.4-2.2-2.22.6-1.7-2.1
Bone: cortical thickness0.80.91.4-0.9-1.1-1.1-0.7-1.1-0.6-0.81.1-1.1-0.8-1.1-1.21.0-0.6-1.1
Bone: cortical tissue density0.91.11.7-0.8-1.2-1.2-0.5-1.3-0.5-0.61.3-1.3-0.8-1.3-1.21.3-0.9-1.2
Bone: elastic displacement1.01.13.4-1.4-0.8-0.9-1.8-0.6-1.2-1.50.7-0.7-1.5-0.8-1.20.1-0.9-0.6
Bone: elastic work1.31.73.3-1.2-1.3-1.2-1.4-1.4-0.6-0.81.5-1.5-1.3-1.3-1.81.5-1.2-1.2
Bone: endosteal estimation3.77.910.12.63.02.92.43.11.72.0-3.23.22.83.23.1-2.92.73.0
Bone: endosteal perimeter4.89.913.02.93.33.22.83.51.62.1-3.63.63.23.53.6-3.33.03.2
Bone: final force0.20.41.70.70.10.20.7-0.21.30.90.7-0.60.50.0-0.31.0-0.0-0.0
Bone: final moment0.20.41.60.70.10.20.7-0.21.30.90.6-0.60.5-0.0-0.31.0-0.1-0.0
Bone: marrow area3.78.010.62.63.02.92.43.11.62.0-3.23.22.83.23.1-3.02.73.0
Bone: maximum diameter0.61.02.21.30.90.91.50.81.11.1-0.80.81.40.91.1-0.41.00.7
Bone: maximum force1.01.75.31.90.91.12.00.52.32.1-0.20.31.80.80.80.60.70.6
Bone: maximum moment0.81.54.71.80.81.01.80.42.22.0-0.10.21.70.80.70.60.60.6
Bone: minimum diameter3.26.07.72.42.62.62.32.71.81.9-2.62.62.52.72.8-2.32.22.6
Bone: periosteal estimation1.73.54.92.01.91.82.01.81.61.7-1.81.82.22.02.1-1.41.81.8
Bone: periosteal perimeter0.81.42.01.31.31.21.21.31.01.0-1.01.01.31.31.4-0.91.01.2
Bone: post-yield work5.47.410.43.12.82.72.92.72.32.6-2.72.83.22.83.0-2.22.42.5
Bone: stiffness0.30.51.51.00.50.51.20.31.10.9-0.20.21.10.50.80.10.70.3
Bone: tissue strength0.10.10.5-0.00.30.2-0.20.5-0.3-0.3-0.50.40.00.40.3-0.70.20.4
Bone: trabecular number0.50.71.71.20.70.81.30.41.31.3-0.40.51.20.70.50.10.60.5
Bone: trabecular spacing0.91.22.7-1.5-0.7-0.7-1.6-0.5-1.2-1.51.0-1.1-1.6-0.8-1.10.4-0.9-0.5
Bone: trabecular thickness0.50.61.10.60.60.50.60.80.10.3-1.01.00.80.81.0-1.00.80.6
Bone: trabecular tissue density0.60.83.0-0.60.30.0-0.80.8-1.4-1.2-1.11.0-0.40.51.0-1.70.60.4
Breakpoint value in progressive ratio session2.62.94.8-1.3-1.8-1.7-0.6-2.1-0.8-0.82.2-2.2-1.3-2.0-2.12.2-1.2-1.9
Distance traveled before self-admin0.40.41.60.1-0.5-0.40.4-0.70.60.31.1-1.10.0-0.6-0.41.3-0.3-0.7
Distance traveled after self-admin0.00.00.10.0-0.2-0.20.1-0.10.20.00.3-0.30.1-0.20.20.4-0.2-0.3
Delta time in closed arm before/after self-admin0.80.72.6-0.3-0.5-0.4-0.0-1.00.40.41.1-1.0-0.6-0.8-1.41.6-0.7-0.8
Delta time in open arm before/after self-admin0.60.61.4-0.2-0.8-0.70.2-1.0-0.00.01.2-1.2-0.2-0.9-0.61.2-0.4-0.9
Diff in mean of infusions in LGA sessions2.73.05.2-1.4-2.0-1.8-0.8-2.3-1.0-0.92.0-2.0-1.4-2.0-2.12.0-1.2-1.9
Extinction: sum of active levers before priming1.01.13.2-0.1-1.0-0.70.5-1.40.30.41.4-1.3-0.1-1.2-1.21.8-0.5-1.3
Active lever presses in extinction session 61.91.83.5-0.9-1.3-1.4-0.3-1.4-0.5-0.61.9-1.9-0.8-1.6-1.51.8-0.6-1.9
Delta distance traveled before/after self-admin0.10.10.5-0.20.20.1-0.50.4-0.5-0.4-0.50.5-0.20.30.2-0.7-0.00.4
Delta ambulatory time before/after self-admin0.20.20.6-0.50.1-0.0-0.70.2-0.7-0.7-0.40.3-0.50.10.0-0.6-0.10.3
Time in closed arm before self-admin0.20.30.90.60.40.40.50.50.40.4-0.50.50.70.51.0-0.50.30.5
Time in closed arm after self-admin0.10.10.20.10.40.30.00.4-0.1-0.0-0.50.50.00.40.3-0.50.20.3
Time in open arm before self-admin0.30.31.4-0.8-0.1-0.3-1.20.0-0.7-0.9-0.20.2-0.9-0.1-0.6-0.4-0.3-0.0
Time in open arm after self-admin1.41.52.0-1.4-1.3-1.4-1.2-1.2-1.4-1.31.1-1.1-1.4-1.3-1.10.8-0.9-1.3
Sum of active levers in priming session hrs 5-61.31.32.3-0.9-1.3-1.3-0.4-1.3-0.7-0.81.5-1.5-0.8-1.4-1.21.3-0.4-1.5
Time to tail flick, vehicle, before self-admin1.21.22.61.51.01.21.60.81.51.6-0.70.81.41.00.8-0.20.40.8
Time to tail flick, vehicle, after self-admin0.30.31.30.70.50.60.70.31.10.9-0.00.10.50.3-0.30.4-0.10.4
Time to tail flick, test, before self-admin1.01.02.01.30.91.01.10.81.21.4-1.01.11.20.91.1-0.50.00.9
Time to tail flick, test, after self-admin0.10.10.4-0.5-0.3-0.5-0.5-0.2-0.6-0.60.1-0.1-0.4-0.30.2-0.10.0-0.3
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.4-0.2-0.3-0.5-0.2-0.1-0.30.4-0.4-0.5-0.3-0.50.4-0.3-0.2
Delta time to tail flick, test, before/after SA2.42.23.1-1.8-1.6-1.6-1.5-1.4-1.6-1.71.5-1.6-1.7-1.5-1.40.9-0.4-1.5
Ambulatory time before self-admin0.40.51.4-0.1-0.7-0.60.1-0.80.30.11.1-1.1-0.1-0.7-0.61.2-0.2-0.8
Ambulatory time after self-admin0.50.61.11.00.70.70.90.71.00.9-0.40.41.00.70.9-0.30.50.7
Total heroin consumption4.55.48.5-1.8-2.5-2.4-1.0-2.9-1.1-1.12.8-2.8-1.8-2.8-2.92.9-1.6-2.9
Area under the delay curve0.60.61.11.10.70.60.60.60.91.1-0.90.91.00.71.0-0.40.20.5
Delay disc. indifference point, 0s delay2.12.23.01.61.71.71.01.51.61.6-1.51.61.51.71.4-1.00.71.7
Delay disc. indifference point, 16s delay0.40.40.70.80.60.60.80.50.70.8-0.40.50.80.50.8-0.20.20.4
Delay disc. indifference point, 2s delay1.82.03.11.61.51.41.01.41.31.3-1.51.61.51.51.7-1.20.81.4
Delay disc. indifference point, 24s delay0.10.10.30.40.20.20.10.10.50.5-0.30.40.40.20.5-0.00.00.2
Delay disc. indifference point, 4s delay0.60.61.61.20.60.60.70.31.11.3-0.91.01.10.60.7-0.10.10.3
Delay disc. indifference point, 8s delay0.20.20.80.30.20.0-0.10.1-0.10.3-0.80.90.40.20.7-0.5-0.1-0.0
Delay discount exponential model param0.60.71.2-1.1-0.8-0.6-0.6-0.6-0.9-1.10.9-1.0-1.1-0.7-1.00.5-0.2-0.5
Delay discount hyperbolic model param0.80.81.5-1.2-0.9-0.8-0.7-0.7-1.1-1.21.0-1.1-1.2-0.8-1.10.5-0.3-0.6
Fecal boli incidents, locomotor time 10.10.10.2-0.1-0.10.20.40.1-0.3-0.20.1-0.1-0.10.20.4-0.30.50.5
Change in fecal boli incidents, locomotor task1.41.32.30.91.41.10.01.40.90.7-1.51.50.81.41.1-1.20.61.4
Time >=10cm from walls, locomotor time 12.22.23.71.11.61.61.41.90.40.7-1.71.61.31.71.8-1.91.31.6
Bouts of movement, locomotor time 14.24.76.2-2.3-2.4-2.4-1.4-2.3-2.1-2.02.3-2.4-2.2-2.5-2.21.8-1.1-2.4
Total resting periods, locomotor time 12.62.94.0-1.8-1.9-1.9-1.0-1.8-1.7-1.51.9-1.9-1.7-2.0-1.61.5-0.9-2.0
Rest time, locomotor task time 10.20.21.2-0.5-0.2-0.3-0.40.1-1.1-0.7-0.50.5-0.3-0.10.4-0.8-0.2-0.2
Distance moved, locomotor task time 10.30.30.90.70.70.70.70.61.00.7-0.10.10.60.6-0.10.10.40.5
Vertical activity count, locomotor time 10.20.30.60.10.60.4-0.20.7-0.2-0.2-0.60.60.10.60.4-0.80.70.5
Time >=10cm from walls, locomotor time 20.10.10.3-0.3-0.3-0.3-0.2-0.1-0.5-0.60.1-0.1-0.2-0.10.4-0.30.2-0.1
Bouts of movement, locomotor time 21.51.63.8-1.0-1.1-0.7-0.2-1.4-0.2-0.31.9-2.0-1.2-1.3-1.81.8-0.9-1.0
Total resting periods, locomotor time 21.11.22.8-0.9-0.9-0.5-0.1-1.1-0.3-0.31.7-1.7-1.1-1.1-1.61.5-0.7-0.8
Rest time, locomotor task time 20.40.52.0-0.20.60.6-0.00.9-0.9-0.4-1.01.0-0.10.60.6-1.40.20.7
Distance moved, locomotor task time 20.50.51.1-0.6-0.8-0.9-0.6-0.9-0.2-0.60.9-0.9-0.5-0.8-0.60.8-0.4-1.0
Vertical activity count, locomotor time 21.31.42.9-1.4-1.2-1.4-1.7-1.1-1.4-1.50.8-0.8-1.4-1.2-0.70.5-0.7-1.3
Weight adjusted by age0.50.62.10.1-0.20.20.9-0.60.80.71.3-1.2-0.2-0.4-1.01.4-0.1-0.1
Seeking ratio, delayed vs. immediate footshock0.30.30.50.70.50.50.70.40.50.7-0.60.60.70.40.4-0.30.20.4
Locomotion in novel chamber1.92.44.21.21.71.50.82.00.50.6-1.81.81.31.82.0-2.11.21.6
Locomotion in novel chamber post-restriction0.40.51.8-1.0-0.2-0.3-1.00.1-1.3-1.2-0.30.2-0.9-0.1-0.0-0.8-0.1-0.1
Progressive ratio0.30.30.70.70.60.70.80.60.50.6-0.50.50.80.60.2-0.40.60.4
Food seeking constrained by brief footshock0.10.10.4-0.30.10.0-0.70.1-0.1-0.40.1-0.1-0.50.1-0.2-0.10.00.2
Seeking ratio, punishment vs. effort0.20.20.9-0.6-0.3-0.4-0.9-0.3-0.2-0.50.3-0.3-0.8-0.3-0.20.3-0.5-0.1
Run reversals in cocaine runway, females1.01.02.41.40.81.01.20.51.51.5-0.70.81.30.80.7-0.10.50.8
Run reversals in cocaine runway, males0.20.20.8-0.3-0.2-0.5-0.9-0.1-0.6-0.6-0.50.5-0.2-0.10.7-0.7-0.1-0.3
Latency to leave start box in cocaine runway2.62.93.81.81.81.71.41.81.41.5-1.91.91.91.81.9-1.61.11.6
Latency to leave start box in cocaine runway, F0.70.81.31.10.80.80.90.81.01.0-0.80.91.20.81.0-0.50.30.7
Latency to leave start box in cocaine runway, M1.91.84.30.71.31.10.41.6-0.10.1-1.91.90.91.51.6-2.11.31.3
Cd content in liver0.30.30.9-0.10.60.5-0.90.8-0.2-0.5-0.40.4-0.30.60.5-1.00.10.7
Co content in liver1.31.54.5-1.8-0.9-1.1-2.1-0.4-1.9-2.10.5-0.6-1.7-0.8-0.7-0.3-0.4-0.6
Cu content in liver0.20.20.4-0.4-0.6-0.6-0.3-0.6-0.0-0.10.4-0.4-0.3-0.6-0.50.7-0.5-0.4
Fe content in liver0.00.00.10.10.10.20.30.10.20.1-0.00.00.10.1-0.20.0-0.00.1
K content in liver1.01.02.51.50.80.91.50.51.51.6-0.60.61.40.80.4-0.00.40.5
Mg content in liver1.41.43.21.51.31.41.31.11.81.6-0.80.81.31.30.7-0.40.51.2
Mn content in liver0.30.40.90.5-0.4-0.30.6-0.70.60.70.5-0.40.5-0.5-0.61.0-0.6-0.8
Na content in liver0.10.10.50.30.10.20.10.00.70.30.4-0.40.10.10.10.4-0.20.2
Rb content in liver1.01.32.40.61.31.20.21.50.30.3-1.41.40.61.41.1-1.60.91.5
Se content in liver0.20.21.20.60.00.21.1-0.10.50.8-0.20.20.80.00.10.20.1-0.1
Sr content in liver2.82.57.0-0.6-1.5-1.2-0.3-1.90.40.22.3-2.2-0.9-1.8-1.92.7-1.6-1.6
Zn content in liver1.11.24.10.1-0.7-0.40.4-1.11.10.71.7-1.6-0.3-0.9-1.42.0-1.2-0.8