Hub : Genes

Mrpl54

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000020464 0.12 0.07 2.2e-13 0.11 0.11 0.11 0.11 7.6e-12 2.2e-12 2.1e-12 8.1e-12
2 Adipose mRNA stability ENSRNOG00000020464 0.04 0.03 1.8e-04 0.03 0.03 0.02 0.03 1.7e-04 5.9e-04 1.5e-03 6.4e-04
3 BLA gene expression ENSRNOG00000020464 0.53 0.17 0.0e+00 0.28 0.35 0.34 0.35 2.1e-15 1.6e-19 1.2e-18 2.0e-19
4 BLA mRNA stability ENSRNOG00000020464 0.1 0.07 9.4e-07 0.12 0.12 0.11 0.11 1.0e-06 8.7e-07 1.9e-06 2.1e-06
5 Brain gene expression ENSRNOG00000020464 0.4 0.16 0.0e+00 0.23 0.29 0.28 0.29 5.3e-21 4.3e-27 1.5e-25 8.2e-27
6 Brain mRNA stability ENSRNOG00000020464 0.07 0.05 6.6e-06 0.05 0.04 0.04 0.04 1.6e-05 7.3e-05 5.2e-05 8.4e-05
7 IL gene expression ENSRNOG00000020464 0.27 0.17 3.3e-04 0.11 0.08 0.04 0.09 1.3e-03 5.1e-03 4.6e-02 3.0e-03
8 Liver gene expression ENSRNOG00000020464 0.07 0.04 4.4e-08 0.07 0.06 0.07 0.06 5.5e-08 2.3e-07 6.1e-08 1.6e-07
9 NAcc gene expression ENSRNOG00000020464 0.29 0.18 1.8e-14 0.17 0.16 0.18 0.16 9.5e-13 2.8e-12 3.4e-13 6.9e-12
10 NAcc mRNA stability ENSRNOG00000020464 0.04 0.03 1.5e-03 0.03 0.03 0.03 0.03 3.7e-03 4.1e-03 5.2e-03 4.6e-03
11 OFC gene expression ENSRNOG00000020464 0.5 0.19 3.0e-08 0.26 0.28 0.29 0.26 8.0e-07 2.3e-07 1.0e-07 8.5e-07
12 OFC mRNA stability ENSRNOG00000020464 0.12 0.1 5.8e-03 0.09 0.1 0.03 0.06 3.7e-03 2.7e-03 6.2e-02 1.4e-02
13 PL gene expression ENSRNOG00000020464 0.37 0.19 0.0e+00 0.19 0.22 0.22 0.23 3.3e-14 1.5e-16 1.5e-16 1.5e-17
14 PL mRNA stability ENSRNOG00000020464 0.11 0.07 1.9e-10 0.13 0.13 0.13 0.13 4.4e-10 2.7e-10 2.4e-10 2.3e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail5.317.022.54.44.53.24.73.14.64.64.64.04.63.64.7-0.74.6
BMI without tail1.53.25.61.71.90.92.10.82.42.02.01.42.01.22.4-1.02.0
Body weight0.93.95.42.02.21.52.31.42.32.22.21.82.21.62.3-0.62.2
Epididymis fat weight0.30.61.0-0.9-0.7-1.0-0.6-1.0-0.3-0.8-0.8-1.0-0.8-0.9-0.4-0.7-0.8
Glucose0.91.42.01.21.30.91.40.91.41.31.41.11.31.01.4-0.41.2
Heart weight0.50.71.2-1.0-0.9-1.1-0.7-1.1-0.4-0.8-0.8-1.0-0.9-1.0-0.5-0.7-0.9
Left kidney weight0.10.31.80.2-0.10.5-0.20.6-0.8-0.00.00.4-0.00.4-0.51.3-0.0
Right kidney weight1.13.24.8-1.8-2.0-1.2-2.1-1.2-2.2-2.0-1.9-1.5-1.9-1.4-2.20.8-2.0
Tail length3.09.211.3-3.4-3.3-2.9-3.2-2.8-2.7-3.3-3.2-3.2-3.3-3.1-3.0-0.6-3.3
Length with tail1.55.57.5-2.5-2.6-1.8-2.7-1.7-2.6-2.6-2.5-2.3-2.6-2.1-2.70.4-2.6
Length without tail0.10.21.20.2-0.00.7-0.20.7-0.60.0-0.00.4-0.00.5-0.51.1-0.0
Liver weight, left1.82.94.81.71.91.12.01.02.21.91.91.51.81.32.2-0.81.9
Liver weight, right1.52.53.21.71.81.41.81.41.51.81.81.61.71.51.7-0.11.7
Parametrial fat weight0.51.01.3-1.1-1.0-1.0-1.0-1.0-0.7-1.0-1.1-1.1-1.1-1.1-0.9-0.4-1.0
Retroperitoneal fat weight0.31.02.60.91.10.41.20.31.61.01.00.51.10.51.3-1.11.2
Intraocular pressure0.50.62.0-0.8-0.5-1.2-0.2-1.30.4-0.4-0.5-0.9-0.5-1.00.2-1.4-0.5
Extensor digitorum longus weight3.212.821.83.53.92.14.32.04.73.94.13.03.92.54.6-2.04.0
Soleus weight7.622.128.25.05.23.95.33.74.95.25.24.75.24.35.3-0.65.2
Tibialis anterior weight0.93.04.31.81.81.51.91.51.71.92.11.81.81.61.9-0.11.8
Tibia length0.92.53.1-1.7-1.7-1.5-1.7-1.4-1.4-1.7-1.7-1.7-1.8-1.6-1.6-0.3-1.7
Number of licking bursts0.30.41.9-0.4-0.1-0.80.1-0.90.8-0.2-0.2-0.6-0.0-0.70.4-1.40.1
Food consumed during 24 hour testing period0.40.50.60.70.70.50.80.50.80.70.70.60.80.60.8-0.20.8
Times rat made contact with spout0.20.20.80.10.3-0.20.4-0.30.80.30.3-0.00.3-0.10.6-0.90.2
Mean time between licks in bursts4.05.56.9-2.6-2.5-2.3-2.5-2.3-2.1-2.6-2.6-2.5-2.5-2.4-2.3-0.5-2.5
Mean num. licks in bursts0.10.10.30.30.20.50.10.5-0.10.30.30.50.20.50.00.50.0
Std. dev. time between licks in bursts0.50.61.8-0.5-0.70.0-0.90.1-1.3-0.8-0.8-0.3-0.7-0.2-1.21.2-0.7
Water consumed over 24 hours0.91.11.91.21.01.40.81.40.31.01.01.31.01.30.51.11.0
Indifference point 0 sec0.20.30.40.60.60.60.50.60.50.50.50.50.60.60.50.10.6
Indifference point AUC1.01.21.4-1.2-1.2-1.0-1.2-1.0-1.1-1.2-1.1-1.1-1.2-1.1-1.10.0-1.1
Indifference point function ln k0.20.30.50.50.60.40.60.40.70.60.50.40.60.40.6-0.30.6
Indifference point function log k0.20.30.50.50.60.40.60.40.70.60.50.40.60.40.6-0.30.6
Delay discounting total patch changes 0 sec0.10.20.30.40.50.40.50.40.50.40.40.40.50.40.4-0.10.5
Delay discounting total patch changes 12 sec0.20.30.90.20.4-0.20.6-0.21.00.40.40.10.5-0.00.8-0.90.4
Delay discounting total patch changes 18 sec0.91.21.6-1.2-1.2-1.0-1.2-1.0-1.1-1.2-1.3-1.1-1.2-1.1-1.20.1-1.1
Delay discounting total patch changes 24 sec0.10.10.2-0.2-0.3-0.1-0.3-0.1-0.4-0.3-0.3-0.1-0.2-0.1-0.40.3-0.4
Delay discounting total patch changes 6 sec0.10.20.3-0.5-0.5-0.4-0.5-0.4-0.3-0.6-0.6-0.5-0.4-0.4-0.5-0.1-0.4
Delay discounting time to switch 0 sec2.13.14.32.01.82.11.72.11.11.81.82.01.92.01.31.01.7
Delay discounting water rate 0 sec0.50.72.1-0.9-0.6-1.3-0.3-1.30.5-0.5-0.6-1.0-0.5-1.10.1-1.5-0.4
Delay discounting water rate 12 sec0.60.92.90.50.8-0.31.1-0.41.70.80.80.10.8-0.01.5-1.60.9
Delay discounting water rate 18 sec1.62.16.5-1.4-0.9-2.1-0.5-2.20.8-0.9-1.0-1.7-0.8-1.90.2-2.5-0.8
Delay discounting water rate 24 sec1.31.79.8-0.7-0.1-1.70.4-1.81.9-0.1-0.1-1.1-0.1-1.41.1-3.1-0.1
Delay discounting water rate 6 sec1.21.83.6-1.5-1.1-1.9-0.8-1.90.1-1.1-1.1-1.6-1.1-1.7-0.4-1.8-1.2
Locomotor activity2.33.67.4-1.8-2.1-0.9-2.3-0.7-2.7-2.1-2.1-1.4-2.0-1.2-2.61.4-2.0
Locomotor testing distance1.42.44.4-1.5-1.7-0.9-1.9-0.8-2.1-1.7-1.8-1.3-1.7-1.1-2.00.9-1.6
Locomotor testing rearing0.10.10.2-0.3-0.3-0.4-0.2-0.4-0.1-0.3-0.3-0.4-0.3-0.4-0.1-0.3-0.2
Light reinforcement 14.58.211.1-3.1-3.2-2.2-3.3-2.1-3.1-3.1-3.1-2.6-3.1-2.6-3.30.5-3.2
Light reinforcement 21.41.82.5-1.4-1.5-1.0-1.6-1.0-1.5-1.5-1.5-1.3-1.5-1.2-1.60.2-1.4
Reaction time number correct0.40.51.90.30.5-0.30.8-0.41.40.50.50.00.6-0.11.1-1.30.6
Reaction time mean minus median0.70.91.5-0.9-1.1-0.7-1.1-0.6-1.2-1.0-1.0-0.8-1.0-0.7-1.10.5-0.9
Reaction time mean minus median AUC0.50.63.10.50.21.0-0.11.1-0.90.20.20.70.10.8-0.51.70.4
Reaction time num false alarms0.00.00.2-0.00.0-0.20.1-0.30.30.00.1-0.10.1-0.20.3-0.40.0
Reaction time num false alarms AUC0.10.10.7-0.10.1-0.40.2-0.50.60.10.1-0.20.1-0.30.5-0.80.1
Reaction time trials correct on left0.40.51.90.30.5-0.30.8-0.41.40.50.50.00.6-0.11.1-1.30.6
Reaction time trials on left0.40.51.80.30.6-0.30.8-0.31.30.60.50.10.6-0.01.1-1.20.6
Reaction time mean0.30.41.70.50.20.80.10.9-0.60.20.20.60.30.7-0.21.30.4
Reaction time mean AUC0.30.41.60.60.30.90.20.9-0.50.30.30.70.40.8-0.11.30.5
Median of all reaction times0.60.91.61.10.81.30.61.3-0.00.80.81.10.81.20.31.20.9
Reaction time omissions0.20.20.6-0.4-0.5-0.2-0.6-0.2-0.7-0.6-0.5-0.4-0.5-0.3-0.70.5-0.4
Reaction time false alarm rate0.00.00.00.10.10.10.10.1-0.10.00.10.10.10.10.00.20.1
Reaction time premature initiation rate1.31.82.5-1.5-1.3-1.5-1.2-1.6-0.5-1.4-1.4-1.6-1.3-1.6-0.9-1.0-1.4
Reaction time premature initiations1.31.93.6-1.5-1.1-1.8-0.9-1.90.1-1.2-1.3-1.7-1.1-1.7-0.4-1.8-1.2
Std. dev. reaction times0.20.31.0-0.3-0.50.0-0.60.1-1.0-0.5-0.5-0.2-0.5-0.1-0.81.0-0.2
Reaction time trials completed0.40.51.80.30.6-0.30.8-0.31.30.60.50.10.6-0.01.1-1.20.6
Reaction time trials AUC0.40.52.20.10.5-0.50.7-0.61.40.50.4-0.10.5-0.21.1-1.50.5
Social response proportion0.40.41.1-0.5-0.7-0.2-0.8-0.2-1.1-0.7-0.6-0.4-0.7-0.3-0.90.6-0.8
Social responses5.47.013.2-2.6-2.9-1.5-3.1-1.4-3.6-2.9-2.8-2.1-3.0-1.8-3.41.5-3.0
Social time0.50.61.20.80.90.51.00.41.10.90.90.60.90.61.0-0.50.9
Conditioned locomotion1.11.34.00.71.1-0.01.3-0.12.01.11.00.41.10.31.7-1.61.1
Cocaine response after cond. corrected3.43.88.71.72.10.72.30.62.92.02.11.32.11.12.7-1.72.1
Cocaine response after cond. not corrected3.64.09.41.72.10.72.40.63.12.12.11.32.11.12.8-1.92.1
Cocaine response before conditioning0.30.40.9-0.5-0.6-0.2-0.7-0.2-1.0-0.6-0.7-0.4-0.7-0.3-0.90.6-0.7
Saline control response0.00.10.20.10.2-0.10.2-0.10.50.20.1-0.00.2-0.00.3-0.50.1
Condit. Reinf. active minus inactive responses2.73.44.4-2.1-1.9-2.0-1.8-2.0-1.2-1.9-1.9-2.1-1.9-2.0-1.5-0.8-1.9
Condit. Reinf. active-inactive response ratio0.90.92.6-1.0-0.7-1.4-0.4-1.40.4-0.7-0.6-1.1-0.7-1.30.0-1.6-0.7
Condit. Reinf. active responses2.12.93.6-1.9-1.9-1.5-1.9-1.4-1.7-1.9-1.8-1.7-1.8-1.6-1.80.0-1.9
Condit. Reinf. inactive responses0.81.02.2-0.9-1.1-0.4-1.3-0.4-1.5-1.1-1.1-0.7-1.0-0.6-1.40.9-1.1
Condit. Reinf. lever presses2.53.44.4-2.1-2.0-1.9-1.9-1.9-1.4-2.0-2.0-2.0-2.0-2.0-1.7-0.6-2.0
Condit. Reinf. lever reinforcers received1.82.53.1-1.8-1.7-1.5-1.7-1.5-1.3-1.7-1.7-1.6-1.7-1.6-1.5-0.3-1.8
Pavlov. Cond. lever latency0.70.91.41.01.10.71.10.61.21.01.10.91.10.81.2-0.31.1
Pavlov. Cond. magazine entry latency0.40.41.1-0.6-0.7-0.3-0.8-0.2-1.0-0.7-0.7-0.5-0.8-0.4-0.90.5-0.6
Pavlov. Cond. change in total contacts0.81.11.5-1.2-1.2-0.9-1.2-0.9-1.1-1.1-1.1-1.0-1.2-1.0-1.1-0.0-1.2
Pavlov. Cond. index score0.81.11.5-1.1-1.1-0.8-1.2-0.8-1.2-1.1-1.1-1.0-1.2-0.9-1.20.2-1.1
Pavlov. Cond. latency score0.70.91.5-0.9-1.0-0.6-1.1-0.5-1.2-1.0-1.0-0.8-1.1-0.7-1.20.4-1.0
Pavlov. Cond. lever contacts0.81.11.4-1.2-1.1-1.0-1.1-0.9-1.0-1.1-1.1-1.1-1.2-1.0-1.0-0.2-1.2
Pavlov. Cond. magazine entry number0.60.81.70.81.00.41.10.41.31.00.90.71.00.61.2-0.60.9
Pavlov. Cond. intertrial magazine entries0.30.41.40.30.5-0.10.7-0.21.20.40.40.10.70.00.9-0.90.6
Pavlov. Cond. lever-magazine prob. diff.0.81.01.6-1.0-1.1-0.7-1.2-0.6-1.3-1.1-1.1-0.9-1.2-0.8-1.20.4-1.1
Pavlov. Cond. response bias1.82.53.2-1.7-1.7-1.5-1.7-1.4-1.5-1.7-1.7-1.6-1.8-1.5-1.6-0.2-1.7
Conditioned reinforcement - actives2.32.33.2-1.6-1.6-1.2-1.7-1.1-1.8-1.7-1.7-1.4-1.7-1.2-1.70.5-1.6
Conditioned reinforcement - inactives0.40.51.80.40.6-0.10.8-0.21.30.60.50.10.6-0.01.0-1.30.6
Conditioned locomotion7.18.510.7-3.2-3.2-2.5-3.3-2.4-3.0-3.2-3.2-2.9-3.2-2.7-3.20.3-3.2
Intermittent access intake day 1-15 change6.76.68.1-2.8-2.8-2.4-2.8-2.4-2.3-2.8-2.8-2.7-2.8-2.6-2.6-0.4-2.8
Intermittent access intake escalation7.87.710.2-3.1-2.9-3.0-2.7-3.0-1.8-2.9-2.9-3.2-3.0-3.1-2.3-1.3-2.9
Intermittent access intake escalation 29.19.011.5-3.4-3.2-3.2-3.0-3.2-2.1-3.2-3.1-3.4-3.2-3.3-2.6-1.2-3.2
Intermitt. access day 1 inactive lever presses0.80.81.3-1.0-0.9-1.2-0.7-1.2-0.2-0.9-0.9-1.1-0.9-1.1-0.5-0.9-0.9
Intermitt. access day 15 inactive lever presses0.60.61.0-0.9-0.8-0.9-0.7-1.0-0.3-0.8-0.8-1.0-0.8-1.0-0.5-0.6-0.7
Intermitt. access escalation Index0.90.82.01.00.71.30.51.3-0.30.70.61.10.71.20.11.40.8
Intermittent access day 1 total infusions0.10.10.20.40.30.30.30.30.10.30.20.30.20.30.30.10.4
Intermittent access day 15 total infusions2.22.43.3-1.7-1.6-1.7-1.5-1.7-1.1-1.7-1.7-1.8-1.7-1.8-1.3-0.7-1.5
Intermittent access terminal intake (last 3 days)1.11.21.6-1.1-1.2-1.0-1.2-1.0-1.2-1.2-1.3-1.1-1.3-1.1-1.10.1-1.1
Intermittent access total infusions0.30.30.5-0.6-0.5-0.6-0.5-0.7-0.3-0.6-0.6-0.7-0.6-0.7-0.4-0.4-0.4
Intermittent access day 1 locomotion0.40.40.5-0.7-0.6-0.7-0.6-0.7-0.4-0.6-0.7-0.7-0.7-0.7-0.4-0.4-0.5
Intermittent access day 15 total locomotion3.63.94.9-2.2-2.1-1.9-2.0-1.9-1.7-2.2-2.1-2.1-2.2-2.1-1.9-0.5-2.0
Intermittent access total locomotion1.01.11.5-1.1-1.1-1.0-1.1-0.9-1.1-1.2-1.2-1.1-1.2-1.1-1.1-0.1-1.0
Intermittent access standard deviation3.43.64.5-2.1-2.0-1.9-2.0-1.9-1.6-2.1-2.0-2.1-2.1-2.0-1.8-0.4-2.0
Cocaine induced anxiety0.50.62.0-0.4-0.70.2-0.90.2-1.4-0.6-0.6-0.1-0.60.0-1.21.4-0.7
Post-drug Anxiety0.60.63.70.1-0.30.6-0.60.7-1.4-0.3-0.30.3-0.30.5-1.01.9-0.4
Baseline Anxiety0.10.10.3-0.4-0.3-0.6-0.2-0.60.2-0.3-0.3-0.5-0.2-0.5-0.0-0.6-0.2
Lifetime Intake0.10.10.1-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.4-0.3-0.4-0.3-0.2-0.0-0.1
Incentive Sensitization - Responses0.50.50.8-0.8-0.8-0.9-0.7-0.9-0.5-0.8-0.7-0.8-0.8-0.8-0.5-0.4-0.7
Incentive Sensitization - Breakpoint0.50.50.7-0.8-0.8-0.8-0.7-0.8-0.6-0.8-0.8-0.8-0.8-0.7-0.6-0.1-0.8
Progressive ratio test 1 active lever presses0.10.10.30.20.3-0.10.3-0.10.50.20.1-0.00.2-0.00.5-0.50.3
Progressive ratio test 1 breakpoint0.10.10.30.30.40.10.40.00.50.30.30.20.30.10.5-0.40.5
Progressive ratio test 1 inactive lever presses0.00.00.0-0.0-0.0-0.0-0.1-0.0-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.0-0.0
Progressive ratio test 2 active lever presses0.40.40.7-0.7-0.6-0.8-0.6-0.8-0.3-0.7-0.7-0.8-0.7-0.8-0.4-0.5-0.5
Progressive ratio test 2 breakpoint0.30.40.5-0.6-0.6-0.6-0.6-0.5-0.7-0.7-0.7-0.6-0.7-0.6-0.60.1-0.6
Progressive ratio test 2 inactive lever presses0.00.10.1-0.2-0.2-0.1-0.3-0.1-0.4-0.2-0.3-0.2-0.3-0.1-0.30.2-0.2
Total sessions with >9 infusions0.20.21.20.30.10.5-0.00.6-0.60.10.00.40.10.5-0.31.10.2
Short access day 1 total inactive lever presses0.00.00.1-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.1-0.2
Short access day 10 total inactive lever presses0.30.30.7-0.6-0.4-0.7-0.3-0.80.2-0.4-0.4-0.7-0.4-0.8-0.1-0.8-0.4
Short access day 1 total infusions0.20.21.30.1-0.10.4-0.30.4-0.9-0.1-0.10.2-0.20.3-0.51.10.0
Short access day 10 total infusions0.00.00.1-0.1-0.1-0.2-0.1-0.2-0.2-0.2-0.3-0.2-0.2-0.2-0.10.10.1
Short access total infusions0.10.10.60.20.10.3-0.00.3-0.50.0-0.10.3-0.00.3-0.10.80.2
Short access day 1 locomotion0.60.61.3-0.7-0.8-0.4-0.9-0.3-1.1-0.9-0.9-0.6-0.9-0.6-1.10.5-0.7
Short access day 10 total locomotion4.44.96.0-2.5-2.3-2.2-2.3-2.2-1.8-2.4-2.4-2.4-2.4-2.3-2.1-0.5-2.3
Short access total locomotion0.80.81.4-0.9-1.0-0.7-1.0-0.6-1.2-1.0-1.1-0.8-1.1-0.8-1.10.3-0.8
Compulsive drug intake1.11.11.41.11.11.11.11.10.91.21.11.21.21.20.90.20.9
One hour access (0.3 mA shock)0.10.20.30.40.50.20.50.20.50.40.40.30.40.30.5-0.30.5
One hour access (shock baseline)0.20.20.6-0.5-0.3-0.7-0.2-0.70.1-0.4-0.4-0.6-0.4-0.6-0.0-0.7-0.2
Number of responses in last shaping day0.10.10.2-0.4-0.4-0.3-0.5-0.3-0.5-0.4-0.5-0.4-0.4-0.3-0.50.2-0.3
Context. condit. distance diff. score0.20.30.40.50.60.30.60.30.60.50.60.40.60.40.6-0.20.7
Locomotion velocity, session 10.50.51.9-0.2-0.50.3-0.70.4-1.3-0.5-0.40.0-0.60.1-1.01.4-0.6
Locomotion distance, session 10.50.63.40.50.11.1-0.21.1-0.90.10.20.70.10.9-0.61.80.0
Locomotion velocity, session 22.12.57.0-1.2-1.6-0.2-1.9-0.1-2.6-1.6-1.5-0.8-1.6-0.5-2.32.1-1.7
Locomotion distance, session 20.91.34.5-0.5-1.00.3-1.30.4-2.0-1.0-0.9-0.2-0.90.0-1.72.1-1.1
Locomotion velocity, session 35.36.27.6-2.7-2.7-2.1-2.8-2.0-2.6-2.7-2.7-2.5-2.8-2.3-2.70.2-2.8
Locomotion distance, session 30.00.00.1-0.2-0.1-0.2-0.1-0.2-0.0-0.1-0.0-0.1-0.2-0.2-0.0-0.2-0.2
Stereotopy head waving bouts, day 33.44.16.4-2.0-2.2-1.3-2.4-1.2-2.5-2.2-2.2-1.8-2.2-1.5-2.50.9-2.2
Stereotopy head waving duration, day 34.25.17.2-2.3-2.5-1.7-2.6-1.6-2.6-2.5-2.5-2.1-2.5-1.9-2.70.7-2.5
Locomotion velocity, session 70.50.61.1-0.7-0.8-0.4-0.9-0.3-1.0-0.8-0.8-0.6-0.8-0.5-1.00.6-0.9
Locomotion distance, session 70.10.10.8-0.10.0-0.40.2-0.40.50.10.1-0.20.0-0.30.4-0.90.0
Stereotopy head waving bouts, day 70.40.42.00.60.31.00.11.0-0.60.30.30.70.20.8-0.31.40.3
Stereotopy head waving duration, day 70.40.42.70.3-0.10.8-0.30.8-1.0-0.1-0.10.4-0.10.6-0.71.7-0.0
Locomotion velocity, session 80.60.74.10.2-0.20.8-0.60.9-1.4-0.3-0.30.4-0.30.6-1.02.0-0.3
Locomotion distance, session 80.10.10.5-0.0-0.20.2-0.30.2-0.5-0.2-0.20.1-0.10.1-0.40.7-0.2
Degree of sensitization distance0.30.30.50.60.60.50.60.50.60.60.60.60.70.50.6-0.00.7
Degree of sensitization stereotypy2.32.53.41.81.61.81.51.80.91.61.61.81.61.81.21.01.6
Condit. Reinf. active minus inactive responses3.43.85.0-2.1-2.2-1.5-2.2-1.5-2.1-2.2-2.1-1.9-2.1-1.7-2.20.4-2.2
Condit. Reinf. active-inactive response ratio2.32.43.1-1.8-1.7-1.6-1.6-1.6-1.2-1.7-1.6-1.7-1.7-1.7-1.4-0.5-1.7
Condit. Reinf. active responses2.53.05.6-1.6-1.9-0.9-2.1-0.8-2.4-1.9-1.9-1.4-1.9-1.2-2.31.2-1.9
Condit. Reinf. inactive responses0.50.62.3-0.4-0.60.3-0.90.3-1.4-0.7-0.6-0.1-0.60.0-1.21.5-0.7
Incentive salience index mean1.51.83.6-1.2-1.4-0.6-1.6-0.5-1.9-1.5-1.4-1.0-1.4-0.8-1.81.1-1.4
Condit. Reinf. lever presses0.60.84.10.70.31.3-0.01.4-0.90.20.40.90.31.0-0.52.00.3
Time in familiar zone, hab. session 12.12.02.5-1.6-1.5-1.4-1.5-1.4-1.2-1.5-1.6-1.5-1.5-1.4-1.3-0.3-1.6
Time in novel zone, hab. session 11.51.52.41.41.21.51.01.60.51.11.21.41.21.50.71.21.2
Total zone transitions, hab. session 10.60.82.5-0.4-0.70.2-1.00.3-1.6-0.8-0.7-0.2-0.70.0-1.31.6-0.8
Total locomotion distance, hab. session 10.91.36.3-0.1-0.60.8-1.00.9-2.0-0.6-0.60.3-0.60.5-1.62.5-0.8
Locomotion velocity, hab. session 10.91.34.2-0.6-1.00.3-1.30.4-2.1-1.0-1.0-0.2-1.00.0-1.72.1-1.1
Time in familiar zone, hab. session 26.56.78.6-2.9-2.8-2.7-2.7-2.6-2.1-2.7-2.8-2.8-2.8-2.7-2.4-0.8-2.8
Time in novel zone, hab. session 25.25.26.72.62.42.52.32.51.62.42.42.52.42.51.91.02.4
Total zone transitions, hab. session 21.01.33.41.20.81.60.61.7-0.20.80.81.40.91.50.11.80.7
Total locomotion distance, hab. session 20.50.72.0-0.4-0.70.2-0.90.3-1.4-0.7-0.7-0.1-0.70.0-1.21.4-0.9
Locomotion velocity, hab. session 20.50.73.2-0.3-0.60.5-0.90.5-1.5-0.6-0.60.1-0.60.3-1.31.8-0.8
Novel to familiar place preference ratio4.74.96.52.52.32.52.12.51.32.32.32.52.22.51.71.32.3
Novelty place preference3.03.14.52.01.82.11.62.10.91.81.92.11.72.11.21.31.8
Time in novel zone, NPP test3.33.44.62.11.92.11.72.11.01.92.02.11.82.11.41.21.9
Total zone transitions, NPP test0.20.30.90.50.30.70.20.8-0.20.30.30.60.40.7-0.10.90.2
Total locomotion distance, NPP test0.40.61.90.70.51.10.31.1-0.30.50.50.90.51.0-0.11.40.3
Locomotion velocity, NPP test0.20.41.80.40.20.8-0.00.9-0.60.20.20.60.20.7-0.41.30.0
Pavlov. Cond. lever latency0.40.51.8-0.6-0.4-1.0-0.2-1.00.5-0.4-0.4-0.8-0.3-0.90.2-1.3-0.3
Pavlov. Cond. magazine entry latency2.53.24.1-2.0-2.0-1.7-2.0-1.6-1.7-2.0-2.0-1.9-1.9-1.8-1.8-0.1-1.9
Pavlov. Cond. change in total contacts0.00.00.1-0.2-0.2-0.1-0.2-0.1-0.3-0.2-0.2-0.1-0.2-0.1-0.30.2-0.3
Pavlov. Cond. index score0.20.30.9-0.3-0.50.1-0.60.1-0.9-0.5-0.5-0.2-0.5-0.0-0.80.9-0.5
Pavlov. Cond. latency score0.30.41.7-0.1-0.40.4-0.60.4-1.1-0.4-0.40.1-0.40.2-0.91.3-0.4
Pavlov. Cond. lever contacts0.40.52.60.50.21.0-0.11.0-0.80.20.20.70.10.8-0.51.60.1
Pavlov. Cond. magazine entry number0.50.60.80.80.90.60.90.60.80.90.90.80.80.70.9-0.10.8
Pavlov. Cond. intertrial magazine entries0.40.41.0-0.7-0.5-0.9-0.4-1.00.2-0.6-0.6-0.8-0.4-0.9-0.1-1.0-0.5
Pavlov. Cond. lever-magazine prob. diff.0.40.61.4-0.6-0.8-0.2-0.9-0.1-1.2-0.8-0.8-0.5-0.8-0.3-1.10.9-0.8
Pavlov. Cond. response bias0.81.01.3-1.0-1.1-0.8-1.1-0.7-1.1-1.1-1.1-0.9-1.1-0.8-1.20.3-1.1
Bone: apparent density1.11.87.01.10.61.90.22.0-1.20.60.61.50.61.7-0.52.60.5
Bone surface1.73.015.11.10.32.3-0.32.5-2.20.30.31.70.31.9-1.33.90.3
Bone volume1.72.915.11.10.32.3-0.32.5-2.20.30.31.70.31.9-1.33.90.3
Bone: connectivity density1.01.63.91.30.91.80.61.9-0.51.01.01.60.91.70.02.00.8
Bone: cortical apparent density0.81.01.91.11.10.71.10.71.11.01.00.81.20.81.2-0.21.4
Bone: cortical area1.11.63.01.51.21.70.91.70.11.11.11.51.21.60.61.41.3
Bone: cortical porosity0.30.41.0-0.5-0.6-0.1-0.7-0.1-1.0-0.6-0.6-0.3-0.6-0.2-0.90.8-0.6
Bone: cortical porosity0.30.31.30.40.10.7-0.00.8-0.60.10.10.50.10.6-0.31.20.1
Bone: cortical thickness1.22.02.61.61.51.51.41.51.01.51.51.61.61.51.20.61.6
Bone: cortical thickness0.20.20.7-0.4-0.2-0.6-0.1-0.70.3-0.3-0.3-0.5-0.2-0.60.1-0.8-0.3
Bone: cortical tissue density0.50.71.40.90.90.60.90.50.90.80.80.60.90.61.0-0.21.2
Bone: elastic displacement0.20.20.4-0.5-0.5-0.3-0.6-0.3-0.6-0.5-0.5-0.4-0.6-0.4-0.60.2-0.6
Bone: elastic work0.30.40.70.70.60.80.50.80.10.60.60.70.60.70.30.60.6
Bone: endosteal estimation0.30.71.21.00.81.10.71.10.20.80.81.00.81.00.50.80.9
Bone: endosteal perimeter0.20.42.0-0.1-0.40.4-0.60.5-1.2-0.4-0.40.1-0.40.2-0.91.4-0.3
Bone: final force1.62.73.91.91.62.01.52.00.71.61.61.91.71.91.11.21.7
Bone: final moment1.32.23.21.71.51.81.31.80.61.41.41.81.51.71.01.11.5
Bone: marrow area0.30.71.21.00.81.10.71.10.20.80.81.00.81.00.50.80.9
Bone: maximum diameter0.50.83.0-0.4-0.70.3-1.00.4-1.7-0.8-0.8-0.2-0.70.0-1.41.7-0.6
Bone: maximum force1.52.63.41.81.71.81.51.80.91.61.61.81.71.81.20.91.8
Bone: maximum moment1.22.22.91.71.51.71.41.70.81.51.51.71.61.61.10.91.6
Bone: minimum diameter0.20.31.30.50.30.80.10.9-0.40.30.30.60.30.7-0.11.10.4
Bone: periosteal estimation0.81.63.11.41.11.70.91.80.01.11.11.51.21.60.41.61.3
Bone: periosteal perimeter0.30.52.90.40.10.9-0.21.0-1.00.00.00.60.10.7-0.61.70.2
Bone: post-yield work0.50.71.10.90.90.60.90.60.90.80.80.71.00.70.9-0.11.1
Bone: stiffness3.14.96.22.52.42.22.32.21.82.32.32.42.52.32.10.62.5
Bone: tissue strength1.71.72.51.51.41.31.41.21.11.41.41.31.51.31.30.21.6
Bone: trabecular number0.60.93.6-0.2-0.60.5-0.90.6-1.8-0.6-0.60.2-0.70.3-1.41.9-0.8
Bone: trabecular spacing0.91.26.8-0.40.1-1.30.5-1.41.70.10.1-0.80.1-1.01.2-2.60.1
Bone: trabecular thickness2.32.811.91.40.72.40.12.5-1.60.70.71.90.72.1-0.73.50.6
Bone: trabecular tissue density1.42.04.81.21.50.41.70.32.21.41.40.81.60.62.0-1.41.7
Breakpoint value in progressive ratio session5.46.07.5-2.7-2.6-2.4-2.6-2.4-2.1-2.7-2.7-2.7-2.7-2.5-2.3-0.4-2.5
Distance traveled before self-admin0.30.30.50.60.50.70.50.70.30.60.60.70.60.70.40.40.6
Distance traveled after self-admin0.60.71.2-0.8-0.8-0.5-1.0-0.5-1.1-0.9-0.8-0.7-0.9-0.6-1.10.4-1.0
Delta time in closed arm before/after self-admin0.80.84.4-0.20.3-0.90.6-1.01.50.30.3-0.40.3-0.71.1-2.10.2
Delta time in open arm before/after self-admin1.31.31.61.31.21.11.21.11.01.21.21.11.21.11.10.11.3
Diff in mean of infusions in LGA sessions1.41.52.0-1.3-1.3-1.1-1.4-1.1-1.2-1.4-1.3-1.3-1.4-1.2-1.30.0-1.3
Extinction: sum of active levers before priming2.12.13.2-1.6-1.5-1.8-1.2-1.8-0.6-1.4-1.5-1.7-1.4-1.7-0.9-1.2-1.3
Active lever presses in extinction session 62.62.53.5-1.6-1.7-1.3-1.8-1.2-1.9-1.8-1.7-1.6-1.8-1.4-1.90.4-1.7
Delta distance traveled before/after self-admin1.21.31.8-1.2-1.2-0.9-1.3-0.9-1.3-1.3-1.2-1.1-1.3-1.0-1.30.1-1.3
Delta ambulatory time before/after self-admin1.21.32.4-1.0-1.1-0.7-1.4-0.7-1.5-1.3-1.2-0.9-1.3-0.8-1.50.6-1.3
Time in closed arm before self-admin1.41.52.51.41.21.61.11.60.51.21.21.41.21.50.70.91.2
Time in closed arm after self-admin0.00.00.1-0.1-0.0-0.2-0.1-0.20.0-0.0-0.1-0.1-0.0-0.1-0.1-0.1-0.3
Time in open arm before self-admin1.21.31.7-1.3-1.2-1.1-1.2-1.1-0.9-1.2-1.2-1.2-1.2-1.2-1.1-0.2-1.3
Time in open arm after self-admin0.50.51.00.70.70.50.90.41.00.70.80.60.80.41.0-0.50.9
Sum of active levers in priming session hrs 5-60.00.00.1-0.1-0.0-0.2-0.0-0.20.1-0.1-0.1-0.3-0.1-0.20.0-0.30.0
Time to tail flick, vehicle, before self-admin0.50.52.4-0.2-0.50.4-0.70.5-1.4-0.5-0.40.1-0.50.2-1.01.5-0.5
Time to tail flick, vehicle, after self-admin0.40.40.9-0.7-0.5-0.9-0.3-1.00.1-0.4-0.5-0.7-0.4-0.8-0.0-1.0-0.5
Time to tail flick, test, before self-admin0.40.42.80.2-0.10.6-0.30.7-1.1-0.2-0.20.4-0.10.5-0.61.7-0.1
Time to tail flick, test, after self-admin0.20.20.9-0.1-0.30.2-0.40.3-0.9-0.3-0.30.2-0.30.1-0.60.9-0.3
Delta time to tail flick, vehicle, before/after SA0.60.52.9-0.00.3-0.60.6-0.71.30.40.3-0.20.4-0.41.0-1.70.3
Delta time to tail flick, test, before/after SA0.40.41.1-0.7-0.5-0.9-0.3-0.90.1-0.5-0.4-0.7-0.5-0.8-0.1-1.0-0.5
Ambulatory time before self-admin0.20.20.30.50.50.50.50.50.30.50.50.50.40.50.40.20.5
Ambulatory time after self-admin0.40.40.7-0.6-0.6-0.4-0.8-0.4-0.8-0.7-0.6-0.6-0.7-0.4-0.80.3-0.7
Total heroin consumption1.61.92.9-1.4-1.5-1.1-1.6-1.0-1.7-1.6-1.6-1.4-1.5-1.1-1.60.5-1.4
Area under the delay curve2.22.32.91.71.61.61.61.61.31.71.61.71.61.61.40.41.6
Delay disc. indifference point, 0s delay8.59.212.13.53.23.42.93.42.03.13.23.33.13.42.41.73.1
Delay disc. indifference point, 16s delay0.20.20.30.40.40.40.40.40.30.50.40.60.40.40.30.20.4
Delay disc. indifference point, 2s delay5.96.68.52.92.82.62.62.62.12.72.82.72.72.82.40.92.7
Delay disc. indifference point, 24s delay0.40.40.70.60.70.50.70.50.70.80.70.80.70.50.70.10.7
Delay disc. indifference point, 4s delay1.61.72.61.51.31.61.11.60.61.31.21.61.31.60.81.11.2
Delay disc. indifference point, 8s delay0.80.81.50.81.00.51.10.51.21.01.00.71.00.61.2-0.70.9
Delay discount exponential model param1.92.02.5-1.6-1.5-1.4-1.5-1.4-1.2-1.6-1.5-1.6-1.5-1.5-1.4-0.4-1.5
Delay discount hyperbolic model param2.82.93.6-1.9-1.8-1.7-1.8-1.7-1.5-1.9-1.8-1.9-1.8-1.8-1.6-0.5-1.8
Fecal boli incidents, locomotor time 11.21.32.91.01.20.41.40.31.71.11.20.61.20.61.6-1.21.3
Change in fecal boli incidents, locomotor task0.40.42.20.0-0.30.5-0.50.6-1.1-0.3-0.30.1-0.30.4-0.81.5-0.3
Time >=10cm from walls, locomotor time 10.60.61.20.90.71.10.61.10.20.60.71.00.71.00.31.00.7
Bouts of movement, locomotor time 10.20.20.3-0.5-0.5-0.5-0.4-0.5-0.4-0.5-0.5-0.5-0.5-0.5-0.4-0.2-0.4
Total resting periods, locomotor time 10.20.20.3-0.5-0.5-0.4-0.5-0.4-0.6-0.6-0.5-0.4-0.5-0.4-0.50.1-0.4
Rest time, locomotor task time 10.10.20.3-0.3-0.4-0.1-0.4-0.1-0.6-0.6-0.4-0.4-0.4-0.2-0.50.5-0.3
Distance moved, locomotor task time 10.80.91.71.00.91.30.71.30.21.00.81.20.81.20.41.00.8
Vertical activity count, locomotor time 10.00.00.20.10.2-0.00.2-0.00.40.20.20.00.2-0.00.3-0.40.1
Time >=10cm from walls, locomotor time 20.70.71.70.80.90.41.00.31.30.80.90.60.90.51.2-0.71.0
Bouts of movement, locomotor time 20.30.31.4-0.2-0.40.3-0.60.4-1.0-0.4-0.40.1-0.40.2-0.81.2-0.5
Total resting periods, locomotor time 20.30.31.8-0.1-0.30.4-0.50.5-1.0-0.3-0.30.2-0.30.3-0.81.3-0.4
Rest time, locomotor task time 20.30.41.2-0.4-0.6-0.1-0.7-0.0-1.1-0.6-0.6-0.2-0.6-0.2-0.91.0-0.5
Distance moved, locomotor task time 20.50.61.60.60.80.20.90.11.30.80.80.40.80.31.1-1.00.8
Vertical activity count, locomotor time 20.50.62.20.30.6-0.30.8-0.41.40.50.6-0.10.6-0.11.1-1.50.7
Weight adjusted by age0.20.20.60.20.3-0.30.5-0.30.70.40.2-0.10.3-0.00.7-0.80.4
Seeking ratio, delayed vs. immediate footshock3.74.26.9-2.1-2.3-1.3-2.4-1.2-2.6-2.2-2.2-1.7-2.3-1.6-2.60.9-2.4
Locomotion in novel chamber0.50.71.0-0.9-0.9-1.0-0.8-1.0-0.5-0.8-0.8-0.8-0.9-0.9-0.6-0.2-0.9
Locomotion in novel chamber post-restriction0.60.70.9-0.9-0.9-0.7-1.0-0.7-1.0-1.0-1.0-0.8-0.9-0.8-1.00.2-0.9
Progressive ratio0.10.10.30.20.3-0.10.4-0.10.50.40.40.20.20.10.6-0.50.3
Food seeking constrained by brief footshock0.10.10.1-0.3-0.3-0.2-0.3-0.2-0.3-0.3-0.3-0.2-0.2-0.2-0.30.0-0.4
Seeking ratio, punishment vs. effort0.00.10.2-0.2-0.2-0.0-0.3-0.0-0.3-0.3-0.3-0.2-0.1-0.1-0.40.2-0.2
Run reversals in cocaine runway, females0.40.41.0-0.4-0.6-0.0-0.70.1-1.0-0.5-0.5-0.1-0.5-0.1-0.91.0-0.8
Run reversals in cocaine runway, males0.80.81.9-0.8-0.9-0.3-1.1-0.3-1.4-1.0-1.0-0.5-0.9-0.4-1.30.9-1.0
Latency to leave start box in cocaine runway0.70.82.5-0.5-0.80.1-1.00.2-1.6-0.9-0.8-0.3-0.8-0.1-1.31.5-0.7
Latency to leave start box in cocaine runway, F0.80.94.70.80.41.30.01.4-0.90.20.21.00.41.1-0.52.20.5
Latency to leave start box in cocaine runway, M3.73.54.8-2.1-2.0-2.1-1.8-2.1-1.2-1.9-1.9-2.2-2.0-2.1-1.5-1.0-1.9
Cd content in liver0.20.20.30.50.50.50.50.50.30.50.50.50.50.50.40.10.5
Co content in liver0.70.81.1-1.0-0.9-1.0-0.9-1.0-0.5-0.9-0.9-1.0-0.9-1.0-0.7-0.5-0.9
Cu content in liver0.40.51.30.70.51.00.31.1-0.20.50.60.90.50.90.01.10.5
Fe content in liver0.10.10.4-0.4-0.2-0.6-0.1-0.60.2-0.2-0.3-0.4-0.2-0.50.0-0.6-0.2
K content in liver0.30.31.60.40.20.80.00.8-0.50.20.30.60.20.6-0.31.30.2
Mg content in liver0.50.52.40.50.21.00.01.0-0.60.20.40.80.20.8-0.31.60.2
Mn content in liver1.11.37.00.1-0.51.0-0.91.1-2.0-0.5-0.40.5-0.50.7-1.52.6-0.5
Na content in liver1.31.41.91.31.21.41.11.40.71.21.31.41.21.30.90.71.2
Rb content in liver0.91.22.31.20.91.50.71.5-0.00.90.91.30.91.40.31.50.9
Se content in liver0.10.10.3-0.3-0.4-0.2-0.4-0.1-0.5-0.4-0.4-0.3-0.4-0.2-0.50.3-0.4
Sr content in liver0.40.41.8-0.5-0.3-0.9-0.1-0.90.5-0.3-0.3-0.6-0.3-0.80.2-1.3-0.3
Zn content in liver3.33.76.0-2.2-1.9-2.4-1.6-2.4-0.6-1.9-1.8-2.2-1.9-2.3-1.1-1.7-1.9