Nucb2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS ENSRNOT00000027752 0.04 0.03 4.2e-05 0.03 0.03 0.03 0.03 2.1e-04 6.2e-04 3.0e-04 2.0e-04
2 Adipose alternative TSS ENSRNOT00000107803 0.04 0.03 7.2e-05 0.03 0.03 0.03 0.03 3.0e-04 8.2e-04 4.1e-04 2.8e-04
3 Liver gene expression ENSRNOG00000020456 0.8 0.09 0.0e+00 0.06 0.26 0.26 0.26 7.9e-07 1.4e-28 6.6e-29 4.1e-28
4 Liver isoform ratio ENSRNOT00000027752 0.03 0.03 5.3e-04 0.02 0 0 0.01 6.1e-03 1.0e-01 1.3e-01 1.1e-02
5 Liver isoform ratio ENSRNOT00000107803 0.03 0.02 2.5e-03 0.01 0 0 0.01 1.5e-02 1.1e-01 2.8e-01 3.0e-02
6 Liver intron excision ratio chr1:170750971:170769341 0.03 0.03 3.1e-03 0 0.01 0.01 0 1.7e-01 1.3e-02 4.8e-02 1.2e-01
7 Liver intron excision ratio chr1:170756101:170769341 0.04 0.04 9.6e-04 0.02 0.02 0.01 0.01 4.7e-03 5.1e-03 3.0e-02 3.7e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail5.818.720.74.5-4.62.84.5-4.5-4.54.5
BMI without tail10.922.824.55.0-5.03.94.9-4.9-4.94.9
Body weight4.820.422.64.8-4.83.04.8-4.8-4.54.7
Epididymis fat weight1.53.54.02.0-2.00.92.0-2.0-2.02.0
Glucose0.00.00.0-0.20.20.2-0.20.20.1-0.2
Heart weight0.20.30.30.5-0.50.60.5-0.5-0.50.5
Left kidney weight7.120.423.64.9-4.92.54.8-4.8-4.54.8
Right kidney weight8.123.026.65.1-5.12.25.2-5.2-4.95.2
Tail length2.78.09.12.9-2.93.02.8-2.8-2.72.8
Length with tail1.03.64.02.0-2.01.42.0-2.0-1.82.0
Length without tail0.30.52.0-0.60.6-1.4-0.50.50.7-0.5
Liver weight, left2.64.25.12.3-2.30.82.2-2.2-1.82.2
Liver weight, right3.76.17.32.7-2.71.42.6-2.6-2.42.6
Parametrial fat weight9.718.922.04.7-4.72.04.6-4.6-4.54.6
Retroperitoneal fat weight2.58.29.83.0-3.00.63.1-3.1-3.13.1
Intraocular pressure0.40.61.30.7-0.71.10.6-0.6-0.80.6
Extensor digitorum longus weight2.39.310.43.2-3.21.93.2-3.2-3.23.2
Soleus weight1.02.93.31.8-1.81.11.8-1.8-1.81.8
Tibialis anterior weight3.913.614.83.8-3.82.63.8-3.8-3.83.8
Tibia length0.00.10.10.4-0.40.10.3-0.3-0.10.3
Number of licking bursts5.76.77.6-2.82.8-1.3-2.82.82.7-2.8
Food consumed during 24 hour testing period0.00.00.10.1-0.1-0.30.1-0.10.10.1
Times rat made contact with spout0.50.60.7-0.80.8-0.2-0.80.80.8-0.8
Mean time between licks in bursts1.01.51.91.4-1.40.11.4-1.4-0.81.4
Mean num. licks in bursts2.83.43.82.0-2.00.92.0-2.0-1.92.0
Std. dev. time between licks in bursts2.63.13.61.9-1.91.01.9-1.9-1.71.9
Water consumed over 24 hours3.74.34.9-2.22.2-1.4-2.22.22.2-2.2
Indifference point 0 sec0.50.84.60.4-0.42.10.2-0.2-0.70.2
Indifference point AUC1.21.41.71.3-1.30.91.2-1.2-1.11.2
Indifference point function ln k0.00.10.10.2-0.20.10.3-0.3-0.30.3
Indifference point function log k0.00.10.10.2-0.20.10.3-0.3-0.30.3
Delay discounting total patch changes 0 sec0.71.25.50.7-0.72.30.5-0.5-1.10.5
Delay discounting total patch changes 12 sec0.20.21.3-0.20.21.1-0.30.3-0.2-0.3
Delay discounting total patch changes 18 sec0.20.21.3-0.10.11.1-0.30.3-0.0-0.3
Delay discounting total patch changes 24 sec0.50.71.00.8-0.80.70.8-0.8-1.00.8
Delay discounting total patch changes 6 sec0.20.41.0-0.40.41.0-0.60.60.4-0.6
Delay discounting time to switch 0 sec4.06.16.7-2.62.6-1.8-2.62.62.6-2.6
Delay discounting water rate 0 sec1.11.82.81.3-1.31.71.2-1.2-1.51.2
Delay discounting water rate 12 sec4.97.48.32.9-2.91.52.9-2.9-2.92.9
Delay discounting water rate 18 sec2.22.93.61.8-1.80.41.9-1.9-1.71.9
Delay discounting water rate 24 sec0.40.50.70.8-0.80.50.7-0.7-0.80.7
Delay discounting water rate 6 sec0.50.71.10.8-0.80.80.8-0.8-1.00.8
Locomotor activity0.40.60.70.8-0.8-0.20.8-0.8-0.80.8
Locomotor testing distance0.10.20.30.3-0.3-0.40.4-0.4-0.50.4
Locomotor testing rearing0.10.10.30.3-0.3-0.30.4-0.4-0.50.4
Light reinforcement 10.61.11.3-1.21.2-1.1-1.01.00.9-1.0
Light reinforcement 20.20.30.4-0.50.5-0.2-0.60.60.6-0.6
Reaction time number correct0.20.30.40.5-0.5-0.00.6-0.6-0.60.6
Reaction time mean minus median0.70.91.21.1-1.10.41.0-1.0-0.81.0
Reaction time mean minus median AUC0.91.21.71.3-1.30.41.2-1.2-0.91.2
Reaction time num false alarms0.20.30.5-0.40.40.3-0.60.60.7-0.6
Reaction time num false alarms AUC0.10.10.3-0.10.10.5-0.20.20.4-0.2
Reaction time trials correct on left0.20.30.40.5-0.5-0.00.6-0.6-0.60.6
Reaction time trials on left0.20.30.40.6-0.6-0.00.7-0.7-0.70.7
Reaction time mean0.20.20.30.5-0.50.30.5-0.5-0.50.5
Reaction time mean AUC0.10.10.10.3-0.30.10.3-0.3-0.30.3
Median of all reaction times0.00.00.10.1-0.10.10.1-0.1-0.20.1
Reaction time omissions0.00.00.10.1-0.1-0.10.2-0.2-0.30.2
Reaction time false alarm rate0.30.40.8-0.50.50.3-0.70.70.9-0.7
Reaction time premature initiation rate0.00.00.00.1-0.1-0.10.2-0.2-0.10.2
Reaction time premature initiations0.10.10.10.3-0.3-0.10.4-0.4-0.30.4
Std. dev. reaction times0.81.11.31.1-1.10.61.1-1.1-1.11.1
Reaction time trials completed0.20.30.40.6-0.6-0.00.7-0.7-0.70.7
Reaction time trials AUC0.30.50.60.7-0.70.20.8-0.8-0.80.8
Social response proportion0.70.81.00.9-0.90.01.0-1.0-1.01.0
Social responses0.30.40.5-0.60.60.7-0.70.70.6-0.7
Social time0.50.71.6-0.70.7-1.3-0.60.61.0-0.6
Conditioned locomotion0.20.30.5-0.50.5-0.2-0.50.50.7-0.5
Cocaine response after cond. corrected0.40.50.6-0.80.80.3-0.80.80.4-0.8
Cocaine response after cond. not corrected0.50.61.20.7-0.71.10.6-0.6-0.90.6
Cocaine response before conditioning5.26.37.22.7-2.71.42.7-2.7-2.52.7
Saline control response0.50.70.90.8-0.80.90.8-0.8-0.90.8
Condit. Reinf. active minus inactive responses1.21.51.71.3-1.30.41.3-1.3-1.21.3
Condit. Reinf. active-inactive response ratio0.70.70.90.9-0.90.50.9-0.9-0.90.9
Condit. Reinf. active responses1.11.51.91.3-1.4-0.01.4-1.4-1.11.4
Condit. Reinf. inactive responses0.81.01.21.1-1.10.11.1-1.1-0.91.1
Condit. Reinf. lever presses3.44.65.02.2-2.21.52.2-2.2-2.22.2
Condit. Reinf. lever reinforcers received0.91.21.51.2-1.20.21.2-1.2-1.01.2
Pavlov. Cond. lever latency1.82.53.0-1.61.6-1.5-1.61.61.7-1.6
Pavlov. Cond. magazine entry latency0.00.00.00.1-0.10.10.1-0.1-0.10.1
Pavlov. Cond. change in total contacts0.50.70.90.8-0.80.70.9-0.9-1.00.9
Pavlov. Cond. index score0.60.81.00.9-0.90.80.9-0.9-1.00.9
Pavlov. Cond. latency score0.60.70.90.8-0.80.80.8-0.8-1.00.8
Pavlov. Cond. lever contacts3.54.85.82.2-2.22.12.2-2.2-2.42.2
Pavlov. Cond. magazine entry number0.30.40.40.7-0.70.40.7-0.7-0.70.7
Pavlov. Cond. intertrial magazine entries6.98.910.33.2-3.21.53.2-3.2-2.93.2
Pavlov. Cond. lever-magazine prob. diff.0.50.70.90.8-0.80.80.8-0.8-0.90.8
Pavlov. Cond. response bias1.41.92.21.4-1.41.31.4-1.4-1.51.4
Conditioned reinforcement - actives0.40.40.5-0.60.6-0.3-0.70.70.7-0.7
Conditioned reinforcement - inactives0.91.11.8-1.01.0-0.0-1.11.11.4-1.1
Conditioned locomotion1.21.41.6-1.21.2-1.3-1.21.21.3-1.2
Intermittent access intake day 1-15 change0.80.81.3-0.90.9-1.0-0.80.81.2-0.8
Intermittent access intake escalation0.40.40.8-0.70.7-0.5-0.60.60.9-0.6
Intermittent access intake escalation 20.20.20.5-0.30.3-0.4-0.30.30.7-0.3
Intermitt. access day 1 inactive lever presses0.10.10.2-0.20.20.3-0.30.30.5-0.3
Intermitt. access day 15 inactive lever presses0.50.50.6-0.80.8-0.8-0.70.70.7-0.7
Intermitt. access escalation Index2.32.02.41.5-1.50.61.5-1.5-1.51.5
Intermittent access day 1 total infusions0.20.20.60.4-0.4-0.10.5-0.5-0.80.5
Intermittent access day 15 total infusions0.10.10.6-0.10.1-0.80.0-0.00.10.0
Intermittent access terminal intake (last 3 days)0.30.32.00.1-0.1-1.40.3-0.3-0.10.3
Intermittent access total infusions0.20.20.40.4-0.40.20.4-0.4-0.60.4
Intermittent access day 1 locomotion0.60.71.00.8-0.8-0.50.9-0.9-1.00.9
Intermittent access day 15 total locomotion0.20.30.30.5-0.5-0.50.6-0.6-0.40.6
Intermittent access total locomotion0.60.70.90.8-0.8-0.20.9-0.9-1.00.9
Intermittent access standard deviation0.50.61.30.7-0.71.10.7-0.7-0.60.7
Cocaine induced anxiety1.11.31.61.2-1.30.41.2-1.2-1.11.2
Post-drug Anxiety0.30.40.40.7-0.70.10.7-0.7-0.50.7
Baseline Anxiety1.41.51.7-1.31.3-0.7-1.31.31.2-1.3
Lifetime Intake0.50.51.00.7-0.70.50.7-0.7-1.00.7
Incentive Sensitization - Responses0.50.50.7-0.80.8-0.3-0.80.80.6-0.8
Incentive Sensitization - Breakpoint0.50.60.7-0.80.8-0.4-0.80.80.7-0.8
Progressive ratio test 1 active lever presses0.20.20.50.4-0.40.60.4-0.4-0.70.4
Progressive ratio test 1 breakpoint0.40.40.70.6-0.60.80.5-0.5-0.80.5
Progressive ratio test 1 inactive lever presses0.60.61.60.7-0.71.30.6-0.6-0.70.6
Progressive ratio test 2 active lever presses0.00.00.1-0.00.00.2-0.10.1-0.3-0.1
Progressive ratio test 2 breakpoint0.00.00.10.0-0.00.20.0-0.0-0.30.0
Progressive ratio test 2 inactive lever presses0.00.00.1-0.20.20.1-0.30.30.2-0.3
Total sessions with >9 infusions0.80.81.30.9-0.91.10.8-0.8-1.10.8
Short access day 1 total inactive lever presses0.40.52.3-0.30.31.5-0.50.50.2-0.5
Short access day 10 total inactive lever presses0.60.60.9-0.80.80.2-0.90.90.9-0.9
Short access day 1 total infusions0.50.51.30.6-0.61.10.6-0.6-0.90.6
Short access day 10 total infusions0.20.20.50.3-0.30.70.3-0.3-0.60.3
Short access total infusions1.21.32.01.1-1.11.31.0-1.0-1.41.0
Short access day 1 locomotion0.10.10.3-0.30.30.6-0.30.30.0-0.3
Short access day 10 total locomotion1.71.92.11.4-1.40.91.4-1.4-1.41.4
Short access total locomotion1.92.02.51.4-1.41.21.4-1.4-1.61.4
Compulsive drug intake1.51.51.81.3-1.3-0.11.3-1.3-1.21.3
One hour access (0.3 mA shock)1.21.41.81.3-1.3-0.01.4-1.4-1.11.4
One hour access (shock baseline)0.10.20.3-0.40.4-0.4-0.30.30.6-0.3
Number of responses in last shaping day0.00.00.10.1-0.10.10.2-0.2-0.30.2
Context. condit. distance diff. score0.70.91.0-1.01.0-0.5-1.01.01.0-1.0
Locomotion velocity, session 12.83.03.5-1.81.8-0.9-1.91.91.8-1.9
Locomotion distance, session 10.00.10.1-0.20.2-0.2-0.20.20.3-0.2
Locomotion velocity, session 23.54.14.7-2.22.2-1.2-2.12.12.1-2.1
Locomotion distance, session 20.00.10.1-0.20.2-0.1-0.30.30.3-0.3
Locomotion velocity, session 30.00.00.0-0.00.0-0.2-0.00.00.1-0.0
Locomotion distance, session 30.00.00.0-0.00.0-0.2-0.00.00.2-0.0
Stereotopy head waving bouts, day 31.21.41.8-1.31.3-0.4-1.31.31.0-1.3
Stereotopy head waving duration, day 31.41.72.1-1.41.4-0.3-1.41.41.1-1.4
Locomotion velocity, session 70.10.10.2-0.40.40.1-0.40.40.2-0.4
Locomotion distance, session 70.81.01.2-1.11.1-0.4-1.11.11.0-1.1
Stereotopy head waving bouts, day 70.40.40.5-0.70.7-0.4-0.70.70.6-0.7
Stereotopy head waving duration, day 70.10.20.30.4-0.40.40.4-0.4-0.50.4
Locomotion velocity, session 81.82.22.9-1.51.5-1.2-1.51.51.7-1.5
Locomotion distance, session 80.91.31.6-1.21.2-0.7-1.21.21.3-1.2
Degree of sensitization distance0.40.40.6-0.80.8-0.0-0.70.70.4-0.7
Degree of sensitization stereotypy0.00.00.1-0.20.2-0.3-0.20.20.2-0.2
Condit. Reinf. active minus inactive responses0.10.10.20.4-0.40.10.4-0.4-0.30.4
Condit. Reinf. active-inactive response ratio0.91.01.11.0-1.00.71.0-1.0-1.01.0
Condit. Reinf. active responses0.00.00.00.1-0.1-0.10.1-0.1-0.10.1
Condit. Reinf. inactive responses0.00.00.10.2-0.2-0.30.2-0.20.00.2
Incentive salience index mean0.30.40.50.7-0.70.10.7-0.7-0.40.7
Condit. Reinf. lever presses0.00.00.00.2-0.2-0.20.1-0.10.10.1
Time in familiar zone, hab. session 10.30.30.5-0.50.5-0.5-0.50.50.7-0.5
Time in novel zone, hab. session 10.20.20.30.4-0.40.30.4-0.4-0.50.4
Total zone transitions, hab. session 10.10.10.20.4-0.40.20.3-0.3-0.20.3
Total locomotion distance, hab. session 10.40.50.60.8-0.80.30.8-0.8-0.70.8
Locomotion velocity, hab. session 10.40.60.70.8-0.80.40.8-0.8-0.70.8
Time in familiar zone, hab. session 20.40.40.40.6-0.60.70.7-0.7-0.60.7
Time in novel zone, hab. session 20.00.00.0-0.00.0-0.2-0.00.0-0.1-0.0
Total zone transitions, hab. session 20.20.20.40.6-0.6-0.10.5-0.5-0.20.5
Total locomotion distance, hab. session 20.10.10.30.2-0.2-0.60.2-0.20.20.2
Locomotion velocity, hab. session 20.10.10.20.2-0.2-0.50.2-0.20.10.2
Novel to familiar place preference ratio0.40.40.8-0.50.5-0.9-0.50.50.8-0.5
Novelty place preference0.70.71.2-0.70.7-1.1-0.70.71.0-0.7
Time in novel zone, NPP test0.50.51.1-0.60.6-1.0-0.60.60.9-0.6
Total zone transitions, NPP test0.00.00.10.2-0.20.10.2-0.2-0.20.2
Total locomotion distance, NPP test0.10.10.1-0.30.3-0.4-0.20.20.3-0.2
Locomotion velocity, NPP test0.00.00.1-0.20.2-0.3-0.20.20.2-0.2
Pavlov. Cond. lever latency1.51.92.3-1.51.5-0.8-1.51.51.4-1.5
Pavlov. Cond. magazine entry latency6.38.19.23.0-3.01.83.0-3.0-2.93.0
Pavlov. Cond. change in total contacts2.42.62.91.7-1.71.11.6-1.6-1.61.6
Pavlov. Cond. index score4.76.06.92.6-2.61.52.6-2.6-2.52.6
Pavlov. Cond. latency score4.55.76.62.6-2.61.42.5-2.5-2.42.5
Pavlov. Cond. lever contacts3.03.54.12.0-2.01.12.0-2.0-1.92.0
Pavlov. Cond. magazine entry number3.94.95.7-2.42.4-1.3-2.32.32.2-2.3
Pavlov. Cond. intertrial magazine entries0.30.40.5-0.70.7-0.4-0.60.60.6-0.6
Pavlov. Cond. lever-magazine prob. diff.5.36.67.62.8-2.81.62.7-2.7-2.62.7
Pavlov. Cond. response bias3.13.84.62.2-2.21.02.1-2.1-1.92.1
Bone: apparent density0.40.60.70.8-0.80.40.8-0.8-0.80.8
Bone surface0.61.11.31.1-1.10.71.1-1.1-1.11.1
Bone volume0.71.21.41.2-1.20.71.2-1.2-1.11.2
Bone: connectivity density0.71.11.41.1-1.10.71.1-1.1-1.21.1
Bone: cortical apparent density2.02.63.0-1.71.7-0.7-1.71.71.6-1.7
Bone: cortical area1.72.53.21.6-1.61.41.6-1.6-1.81.6
Bone: cortical porosity2.02.22.61.6-1.60.71.6-1.6-1.41.6
Bone: cortical porosity1.01.01.31.1-1.10.31.1-1.1-0.91.1
Bone: cortical thickness0.10.20.50.3-0.30.70.3-0.3-0.50.3
Bone: cortical thickness0.10.10.2-0.40.4-0.2-0.40.40.3-0.4
Bone: cortical tissue density2.02.63.1-1.71.7-0.7-1.81.81.6-1.8
Bone: elastic displacement3.43.84.3-2.12.1-1.1-2.12.12.0-2.1
Bone: elastic work0.40.50.5-0.70.7-0.3-0.70.70.7-0.7
Bone: endosteal estimation1.43.03.41.8-1.81.01.8-1.8-1.81.8
Bone: endosteal perimeter0.81.61.91.4-1.40.61.4-1.4-1.31.4
Bone: final force1.52.52.71.6-1.61.11.6-1.6-1.61.6
Bone: final moment1.21.92.11.4-1.41.01.5-1.5-1.41.5
Bone: marrow area1.32.83.21.8-1.81.01.7-1.7-1.81.7
Bone: maximum diameter2.13.94.52.1-2.11.32.1-2.1-2.12.1
Bone: maximum force1.22.02.31.5-1.50.81.5-1.5-1.41.5
Bone: maximum moment0.91.51.71.3-1.30.71.3-1.3-1.21.3
Bone: minimum diameter0.51.01.31.0-1.00.81.0-1.0-1.11.0
Bone: periosteal estimation2.04.05.12.0-2.01.62.0-2.0-2.32.0
Bone: periosteal perimeter2.13.64.21.9-1.91.31.9-1.9-2.11.9
Bone: post-yield work4.15.66.42.5-2.51.32.5-2.5-2.52.5
Bone: stiffness0.81.21.31.1-1.10.71.1-1.1-1.11.1
Bone: tissue strength0.20.20.6-0.30.3-0.8-0.30.30.6-0.3
Bone: trabecular number0.00.00.0-0.00.0-0.2-0.00.00.1-0.0
Bone: trabecular spacing0.30.40.60.7-0.70.50.7-0.7-0.70.7
Bone: trabecular thickness0.60.80.90.9-1.00.50.9-0.9-0.90.9
Bone: trabecular tissue density0.20.30.4-0.60.6-0.2-0.60.60.6-0.6
Breakpoint value in progressive ratio session4.95.57.3-2.52.5-2.3-2.12.12.7-2.1
Distance traveled before self-admin0.91.01.3-1.21.2-0.6-1.01.00.9-1.0
Distance traveled after self-admin0.00.00.10.0-0.00.2-0.10.10.0-0.1
Delta time in closed arm before/after self-admin0.40.41.0-0.50.5-1.0-0.50.50.4-0.5
Delta time in open arm before/after self-admin3.43.23.71.7-1.71.61.9-1.9-1.91.8
Diff in mean of infusions in LGA sessions0.50.60.7-0.80.8-0.7-0.80.80.8-0.8
Extinction: sum of active levers before priming0.60.61.7-0.60.6-1.3-0.60.61.0-0.6
Active lever presses in extinction session 60.20.20.20.5-0.50.40.4-0.4-0.10.4
Delta distance traveled before/after self-admin0.91.01.31.2-1.10.90.9-0.9-0.90.9
Delta ambulatory time before/after self-admin0.50.60.90.9-0.90.90.6-0.6-0.60.6
Time in closed arm before self-admin0.91.11.91.1-1.11.40.9-0.9-1.00.9
Time in closed arm after self-admin0.70.70.9-0.90.9-0.7-0.90.90.6-0.9
Time in open arm before self-admin1.11.23.3-1.01.0-1.8-0.80.81.0-0.8
Time in open arm after self-admin2.22.53.11.6-1.60.91.8-1.8-1.41.7
Sum of active levers in priming session hrs 5-60.00.00.00.1-0.1-0.20.1-0.10.10.1
Time to tail flick, vehicle, before self-admin1.11.12.01.0-1.01.41.0-1.0-0.71.1
Time to tail flick, vehicle, after self-admin0.50.50.8-0.80.80.1-0.80.80.9-0.8
Time to tail flick, test, before self-admin0.10.10.70.1-0.10.8-0.20.20.0-0.2
Time to tail flick, test, after self-admin0.20.20.90.1-0.20.90.3-0.3-0.20.3
Delta time to tail flick, vehicle, before/after SA0.10.10.1-0.30.3-0.0-0.30.3-0.0-0.3
Delta time to tail flick, test, before/after SA0.50.40.80.3-0.40.10.9-0.9-0.60.9
Ambulatory time before self-admin1.81.92.5-1.61.6-0.9-1.41.41.3-1.4
Ambulatory time after self-admin0.10.20.2-0.40.40.3-0.50.50.4-0.4
Total heroin consumption2.42.85.5-1.61.6-2.3-1.41.41.8-1.4
Area under the delay curve0.40.50.6-0.70.70.5-0.80.80.5-0.7
Delay disc. indifference point, 0s delay0.30.31.2-0.30.31.1-0.40.40.2-0.4
Delay disc. indifference point, 16s delay4.44.45.1-2.22.2-1.1-2.32.32.2-2.2
Delay disc. indifference point, 2s delay0.60.71.70.8-0.81.30.7-0.7-0.80.7
Delay disc. indifference point, 24s delay2.02.02.4-1.51.5-0.2-1.61.61.5-1.5
Delay disc. indifference point, 4s delay0.50.50.6-0.70.70.5-0.80.80.5-0.7
Delay disc. indifference point, 8s delay1.11.11.4-1.11.1-0.3-1.21.21.0-1.1
Delay discount exponential model param0.40.40.50.6-0.6-0.50.7-0.7-0.50.7
Delay discount hyperbolic model param0.30.30.40.5-0.5-0.60.6-0.6-0.40.6
Fecal boli incidents, locomotor time 10.20.21.4-0.10.11.2-0.20.20.1-0.1
Change in fecal boli incidents, locomotor task0.00.00.0-0.10.1-0.0-0.20.20.2-0.1
Time >=10cm from walls, locomotor time 11.01.12.1-0.90.9-1.4-0.90.90.9-0.9
Bouts of movement, locomotor time 10.00.00.1-0.10.1-0.1-0.10.10.3-0.1
Total resting periods, locomotor time 10.40.50.8-0.60.6-0.8-0.60.60.9-0.6
Rest time, locomotor task time 14.95.47.4-2.22.2-2.7-2.22.22.3-2.2
Distance moved, locomotor task time 12.22.42.61.6-1.61.31.6-1.6-1.61.6
Vertical activity count, locomotor time 10.30.31.40.4-0.41.20.3-0.3-0.50.4
Time >=10cm from walls, locomotor time 20.30.31.70.3-0.3-1.30.3-0.3-0.00.3
Bouts of movement, locomotor time 20.40.40.60.7-0.70.40.7-0.7-0.80.7
Total resting periods, locomotor time 20.60.60.80.8-0.80.50.8-0.8-0.90.8
Rest time, locomotor task time 21.11.31.3-1.21.2-0.9-1.11.11.1-1.2
Distance moved, locomotor task time 20.10.10.6-0.20.2-0.8-0.20.20.3-0.2
Vertical activity count, locomotor time 20.70.70.9-0.90.9-0.2-1.01.01.0-0.9
Weight adjusted by age1.01.11.21.1-1.10.81.1-1.1-1.11.1
Seeking ratio, delayed vs. immediate footshock0.10.10.40.3-0.30.70.2-0.2-0.10.1
Locomotion in novel chamber5.06.16.92.6-2.61.82.5-2.5-2.62.6
Locomotion in novel chamber post-restriction0.30.40.50.6-0.60.50.7-0.7-0.60.7
Progressive ratio0.10.10.9-0.00.0-0.90.1-0.10.20.0
Food seeking constrained by brief footshock0.50.61.0-0.70.8-0.3-0.80.81.0-0.8
Seeking ratio, punishment vs. effort0.10.21.10.1-0.11.10.0-0.0-0.10.1
Run reversals in cocaine runway, females1.51.52.01.2-1.2-0.01.4-1.4-1.41.4
Run reversals in cocaine runway, males2.12.02.7-1.31.30.7-1.61.61.5-1.6
Latency to leave start box in cocaine runway0.10.20.3-0.50.5-0.4-0.40.40.2-0.4
Latency to leave start box in cocaine runway, F0.10.10.10.1-0.1-0.30.3-0.3-0.40.3
Latency to leave start box in cocaine runway, M2.12.02.4-1.51.5-1.0-1.51.51.3-1.5
Cd content in liver0.91.01.1-1.01.0-0.7-1.01.01.0-1.0
Co content in liver1.41.72.0-1.41.4-0.6-1.41.41.2-1.4
Cu content in liver0.10.20.20.4-0.40.20.4-0.4-0.40.4
Fe content in liver1.51.82.0-1.41.4-0.9-1.41.41.4-1.4
K content in liver1.21.21.61.3-1.3-0.11.3-1.3-0.81.3
Mg content in liver0.60.60.80.9-0.9-0.10.9-0.9-0.50.9
Mn content in liver0.80.91.11.1-1.10.01.1-1.1-0.81.1
Na content in liver1.31.41.71.3-1.30.41.3-1.3-1.11.3
Rb content in liver0.10.10.10.3-0.30.00.3-0.3-0.20.3
Se content in liver0.30.30.40.7-0.70.10.7-0.7-0.40.7
Sr content in liver2.32.12.31.5-1.51.01.5-1.5-1.51.5
Zn content in liver1.01.11.31.1-1.10.51.1-1.1-1.11.1