Hub : Genes

Cnih2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000020247 0.03 0.02 2.3e-03 0.02 0 0 0.01 3.4e-03 1.2e-01 8.6e-02 3.1e-02
2 BLA gene expression ENSRNOG00000020247 0.25 0.12 1.0e-09 0.08 0.17 0.16 0.16 6.5e-05 3.3e-09 3.6e-09 6.0e-09
3 Brain gene expression ENSRNOG00000020247 0.35 0.08 0.0e+00 0.25 0.38 0.38 0.39 6.4e-23 1.6e-37 1.7e-37 1.6e-38
4 Brain intron excision ratio chr1:202400839:202401240 0.03 0.02 7.4e-03 0.02 0.01 0.01 0.01 8.2e-03 3.1e-02 6.7e-02 2.4e-02
5 Brain mRNA stability ENSRNOG00000020247 0.04 0.03 1.9e-03 0.03 0.03 0.03 0.02 1.9e-03 1.4e-03 2.1e-03 4.5e-03
6 IL gene expression ENSRNOG00000020247 0.76 0.13 1.4e-09 0.18 0.34 0.36 0.33 3.3e-05 7.2e-09 1.9e-09 9.2e-09
7 NAcc gene expression ENSRNOG00000020247 0.36 0.17 1.6e-11 0.16 0.16 0.16 0.16 4.0e-12 9.1e-12 3.1e-12 1.1e-11
8 OFC gene expression ENSRNOG00000020247 0.73 0.14 1.1e-07 0.24 0.15 0.28 0.23 2.6e-06 1.9e-04 2.1e-07 3.6e-06
9 OFC mRNA stability ENSRNOG00000020247 0.22 0.15 9.6e-03 0 0.03 0.04 0.03 2.4e-01 6.0e-02 3.3e-02 7.4e-02
10 PL gene expression ENSRNOG00000020247 0.59 0.12 0.0e+00 0.38 0.39 0.36 0.38 1.4e-30 4.0e-31 6.4e-29 5.4e-30

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail4.715.423.4-2.64.84.5-2.73.24.64.14.53.34.0
BMI without tail2.04.37.7-1.42.62.1-1.61.52.42.42.81.32.0
Body weight3.213.717.9-3.94.14.0-4.14.23.92.83.13.72.6
Epididymis fat weight1.53.67.52.5-1.7-1.82.7-2.6-1.9-1.1-0.9-1.9-0.7
Glucose0.71.13.31.7-0.3-0.41.8-1.5-0.40.40.8-0.90.7
Heart weight1.52.24.61.6-1.3-1.52.1-2.1-1.40.2-0.4-2.1-0.4
Left kidney weight0.92.64.01.3-1.6-1.61.5-1.7-2.0-1.9-1.3-1.1-1.9
Right kidney weight0.82.24.80.6-1.5-1.11.2-0.8-1.6-2.0-2.2-0.0-2.0
Tail length0.30.93.3-1.1-0.4-0.4-1.80.8-0.4-0.7-0.7-0.1-1.4
Length with tail1.03.59.9-2.91.31.4-3.12.81.30.20.21.9-0.0
Length without tail1.73.77.3-2.31.82.0-2.42.71.90.80.72.31.1
Liver weight, left0.20.30.90.4-0.4-0.80.2-0.6-0.6-1.0-0.3-0.6-0.5
Liver weight, right0.10.20.70.6-0.2-0.6-0.2-0.4-0.3-0.30.2-0.9-0.2
Parametrial fat weight1.12.15.82.2-0.8-1.12.4-2.2-1.2-0.2-0.2-1.4-0.2
Retroperitoneal fat weight3.310.821.84.7-3.0-3.24.3-4.3-3.3-1.6-1.3-3.5-1.5
Intraocular pressure1.82.56.30.4-1.8-1.41.7-1.1-1.8-1.7-2.5-0.4-1.5
Extensor digitorum longus weight5.120.433.8-5.84.84.4-5.75.74.52.62.84.82.3
Soleus weight3.911.418.44.3-3.3-3.53.1-4.1-3.7-2.9-1.7-3.6-2.8
Tibialis anterior weight5.418.741.1-6.43.93.7-6.16.13.81.00.95.01.1
Tibia length0.61.65.7-1.40.30.9-0.91.70.2-1.5-1.22.4-0.5
Number of licking bursts0.30.30.7-0.50.50.6-0.50.70.60.40.00.80.4
Food consumed during 24 hour testing period0.30.41.8-0.1-0.6-0.30.20.2-0.6-1.0-1.30.4-0.4
Times rat made contact with spout0.91.02.0-0.61.11.0-1.00.91.11.41.30.61.1
Mean time between licks in bursts0.40.51.8-0.40.50.6-1.30.60.61.10.8-0.40.2
Mean num. licks in bursts0.10.10.40.4-0.0-0.20.2-0.4-0.00.40.6-0.60.3
Std. dev. time between licks in bursts0.40.52.40.2-0.5-0.9-0.5-0.6-0.7-0.4-0.2-1.5-0.9
Water consumed over 24 hours0.70.81.2-1.00.80.8-1.01.11.01.00.40.81.0
Indifference point 0 sec0.00.10.20.40.00.20.5-0.1-0.10.40.00.10.2
Indifference point AUC2.42.85.9-2.41.51.7-1.82.21.60.50.32.31.0
Indifference point function ln k6.69.416.43.9-2.9-3.32.8-3.9-3.1-1.6-1.0-4.1-2.5
Indifference point function log k6.69.416.43.9-2.9-3.32.8-3.9-3.1-1.6-1.0-4.1-2.5
Delay discounting total patch changes 0 sec0.00.00.10.3-0.2-0.10.2-0.2-0.30.1-0.1-0.2-0.2
Delay discounting total patch changes 12 sec4.25.68.0-2.62.52.6-2.42.82.51.81.42.71.9
Delay discounting total patch changes 18 sec0.91.11.7-1.31.11.2-0.51.01.11.00.71.31.1
Delay discounting total patch changes 24 sec1.41.83.3-1.71.21.4-1.81.81.30.90.51.50.7
Delay discounting total patch changes 6 sec1.52.33.1-1.51.71.6-1.31.61.61.81.11.31.6
Delay discounting time to switch 0 sec3.35.07.6-1.72.62.8-1.32.12.62.02.22.52.3
Delay discounting water rate 0 sec6.09.512.72.7-3.6-3.52.5-3.0-3.6-2.7-2.9-3.0-3.1
Delay discounting water rate 12 sec9.814.723.63.9-4.2-4.62.8-4.2-4.3-2.8-2.5-4.9-3.3
Delay discounting water rate 18 sec3.34.48.62.6-2.2-2.41.4-2.4-2.3-1.1-0.8-2.9-1.8
Delay discounting water rate 24 sec5.87.911.32.6-3.1-3.32.0-3.0-3.2-2.4-2.0-3.4-2.8
Delay discounting water rate 6 sec4.66.712.62.4-2.9-3.21.4-2.8-3.0-1.6-1.5-3.6-2.6
Locomotor activity2.03.26.91.8-2.0-2.20.9-1.9-1.9-0.8-1.0-2.6-1.8
Locomotor testing distance2.54.210.52.3-2.3-2.50.9-2.3-2.0-0.6-0.9-3.2-1.9
Locomotor testing rearing1.32.05.91.8-1.4-1.71.2-1.8-1.10.3-0.1-2.4-0.2
Light reinforcement 10.20.30.50.7-0.6-0.60.4-0.6-0.6-0.3-0.4-0.6-0.3
Light reinforcement 21.41.93.21.2-1.5-1.21.7-1.1-1.5-1.5-1.8-0.2-1.2
Reaction time number correct0.10.20.6-0.8-0.2-0.2-0.70.5-0.2-0.1-0.30.2-0.7
Reaction time mean minus median2.43.26.8-2.31.71.9-1.42.32.00.70.12.61.2
Reaction time mean minus median AUC1.01.33.4-1.80.90.8-1.21.61.10.1-0.41.60.3
Reaction time num false alarms0.60.83.00.5-0.7-1.1-0.4-0.7-0.9-0.1-0.2-1.7-1.2
Reaction time num false alarms AUC0.20.31.1-0.3-0.1-0.5-1.10.0-0.20.30.1-1.1-0.8
Reaction time trials correct on left0.10.20.6-0.8-0.2-0.2-0.70.5-0.2-0.1-0.30.2-0.7
Reaction time trials on left0.20.30.8-0.9-0.1-0.1-0.80.6-0.2-0.1-0.40.2-0.7
Reaction time mean0.10.10.4-0.3-0.00.10.30.20.4-0.5-0.70.60.1
Reaction time mean AUC0.10.10.4-0.10.00.10.40.20.4-0.4-0.60.60.1
Median of all reaction times0.10.10.40.2-0.3-0.20.6-0.30.1-0.6-0.50.1-0.1
Reaction time omissions0.91.22.7-1.71.11.0-1.31.51.20.60.01.30.3
Reaction time false alarm rate0.30.41.80.4-0.3-0.7-0.4-0.5-0.40.10.0-1.3-0.7
Reaction time premature initiation rate1.21.64.7-1.31.11.0-2.21.61.31.40.70.50.5
Reaction time premature initiations1.62.27.4-2.01.11.0-2.72.11.31.20.50.80.2
Std. dev. reaction times0.60.92.3-1.30.70.9-0.51.21.10.0-0.51.50.5
Reaction time trials completed0.20.30.8-0.9-0.1-0.1-0.80.6-0.2-0.1-0.40.2-0.7
Reaction time trials AUC0.10.20.5-0.7-0.2-0.2-0.70.4-0.2-0.1-0.30.1-0.7
Social response proportion1.11.22.2-0.51.01.5-0.61.21.31.10.61.41.3
Social responses0.20.20.4-0.30.30.5-0.50.70.50.30.10.40.6
Social time0.20.20.8-0.60.30.3-0.90.70.60.40.10.20.4
Conditioned locomotion0.80.93.2-1.50.80.7-1.81.20.40.10.70.7-0.2
Cocaine response after cond. corrected0.91.02.91.1-0.9-1.20.7-1.4-1.00.10.1-1.7-0.7
Cocaine response after cond. not corrected0.60.71.81.0-0.7-1.00.7-1.1-0.70.30.0-1.4-0.3
Cocaine response before conditioning0.60.72.2-0.90.70.9-0.31.11.00.2-0.21.50.8
Saline control response3.34.46.3-2.02.22.2-2.42.52.31.61.51.91.9
Condit. Reinf. active minus inactive responses0.20.20.80.5-0.00.30.9-0.10.30.4-0.20.70.6
Condit. Reinf. active-inactive response ratio0.50.52.01.0-0.6-0.31.4-0.7-0.5-0.6-0.70.4-0.2
Condit. Reinf. active responses0.81.12.7-0.10.91.20.20.61.31.50.81.11.7
Condit. Reinf. inactive responses1.92.45.0-0.81.61.4-0.81.01.82.21.80.72.2
Condit. Reinf. lever presses2.33.27.2-1.91.71.9-1.22.22.10.90.52.71.7
Condit. Reinf. lever reinforcers received1.01.43.1-0.41.11.4-0.11.01.51.40.81.51.7
Pavlov. Cond. lever latency0.50.62.10.8-0.7-0.80.4-1.0-0.80.10.1-1.4-0.6
Pavlov. Cond. magazine entry latency4.34.96.8-2.12.42.5-1.92.62.61.91.52.61.9
Pavlov. Cond. change in total contacts2.13.09.1-1.51.72.0-0.72.11.90.60.43.01.6
Pavlov. Cond. index score2.43.17.1-1.61.82.0-1.32.22.00.70.72.71.5
Pavlov. Cond. latency score1.92.45.9-1.41.61.8-1.22.01.80.60.62.41.2
Pavlov. Cond. lever contacts0.30.51.7-0.70.30.5-0.41.00.6-0.5-0.61.30.3
Pavlov. Cond. magazine entry number6.47.912.52.8-2.9-3.22.4-3.4-3.2-2.0-1.6-3.5-2.4
Pavlov. Cond. intertrial magazine entries1.11.42.21.2-1.3-1.31.4-1.5-1.3-1.0-0.8-1.2-0.9
Pavlov. Cond. lever-magazine prob. diff.2.93.77.9-1.92.02.2-1.52.42.20.90.82.81.6
Pavlov. Cond. response bias1.62.15.0-1.51.41.6-1.11.91.70.50.22.21.3
Conditioned reinforcement - actives0.50.51.10.5-0.8-0.60.8-0.4-0.6-1.1-0.90.0-0.5
Conditioned reinforcement - inactives4.65.28.92.4-2.5-2.33.0-2.6-2.5-2.3-1.8-1.5-1.5
Conditioned locomotion8.29.812.23.4-3.4-3.33.2-3.5-3.5-3.0-2.3-2.9-2.5
Intermittent access intake day 1-15 change1.41.42.90.7-1.4-1.20.9-0.7-1.2-1.7-1.5-0.3-1.3
Intermittent access intake escalation0.80.81.60.7-1.0-0.90.8-0.7-0.9-1.3-1.1-0.2-0.9
Intermittent access intake escalation 21.11.12.70.3-1.2-0.90.6-0.5-1.1-1.6-1.5-0.1-1.3
Intermitt. access day 1 inactive lever presses1.51.74.61.4-1.3-1.12.1-1.5-1.5-0.9-1.0-0.8-0.7
Intermitt. access day 15 inactive lever presses1.41.63.71.4-1.4-1.11.9-1.3-1.2-1.3-1.1-0.3-0.7
Intermitt. access escalation Index2.01.84.62.1-0.7-1.11.5-1.9-1.00.30.6-2.1-0.0
Intermittent access day 1 total infusions1.92.16.92.2-0.5-0.72.6-2.1-0.60.61.1-1.21.0
Intermittent access day 15 total infusions3.84.310.52.7-2.0-2.03.2-2.7-1.9-1.4-0.8-1.6-0.6
Intermittent access terminal intake (last 3 days)2.42.68.52.1-1.4-1.42.9-2.1-1.4-0.9-0.6-1.0-0.2
Intermittent access total infusions1.41.55.91.9-0.7-0.82.4-1.7-0.60.00.5-0.80.6
Intermittent access day 1 locomotion1.41.53.61.60.1-0.21.9-1.5-0.01.31.5-1.01.2
Intermittent access day 15 total locomotion2.02.25.82.1-1.4-1.42.4-2.0-1.3-0.8-0.5-1.1-0.3
Intermittent access total locomotion2.12.38.12.5-0.8-0.92.8-2.2-0.9-0.00.6-1.00.6
Intermittent access standard deviation1.11.11.60.8-1.3-1.31.1-1.1-1.2-1.2-0.9-0.8-0.9
Cocaine induced anxiety0.10.10.5-0.1-0.3-0.20.0-0.0-0.4-0.7-0.60.3-0.4
Post-drug Anxiety0.80.82.1-1.40.20.5-0.91.20.3-0.7-1.11.4-0.2
Baseline Anxiety1.21.22.7-1.60.91.0-1.41.61.10.3-0.21.40.2
Lifetime Intake1.21.34.91.7-0.4-0.72.2-1.6-0.40.30.8-0.80.8
Incentive Sensitization - Responses0.10.10.70.5-0.2-0.20.8-0.3-0.1-0.30.10.40.2
Incentive Sensitization - Breakpoint0.20.21.10.7-0.4-0.41.0-0.5-0.4-0.5-0.10.2-0.1
Progressive ratio test 1 active lever presses1.31.43.41.5-1.1-1.31.8-1.6-0.9-0.5-0.3-1.1-0.2
Progressive ratio test 1 breakpoint1.31.33.01.4-1.2-1.31.7-1.5-1.0-0.6-0.4-1.1-0.3
Progressive ratio test 1 inactive lever presses0.50.51.11.0-0.5-0.61.0-1.0-0.50.10.4-0.90.0
Progressive ratio test 2 active lever presses1.92.05.51.9-1.4-1.42.3-1.8-1.2-1.0-0.5-0.9-0.4
Progressive ratio test 2 breakpoint3.13.56.72.3-2.0-2.02.6-2.3-1.8-1.5-1.0-1.5-0.9
Progressive ratio test 2 inactive lever presses4.04.611.02.9-2.0-2.03.3-2.9-2.1-1.3-0.6-1.8-0.5
Total sessions with >9 infusions0.60.61.51.1-0.2-0.41.2-1.2-0.20.50.8-0.90.4
Short access day 1 total inactive lever presses2.12.35.31.9-1.3-1.42.3-2.1-1.5-0.8-0.5-1.6-0.4
Short access day 10 total inactive lever presses2.42.74.41.9-1.6-1.71.8-2.0-1.8-0.8-0.7-2.1-1.1
Short access day 1 total infusions1.21.34.21.6-0.2-0.42.0-1.6-0.30.61.0-1.10.8
Short access day 10 total infusions1.61.75.40.61.00.81.1-0.51.01.72.30.22.1
Short access total infusions0.70.82.20.80.40.11.2-0.80.41.11.5-0.51.2
Short access day 1 locomotion0.90.92.21.30.1-0.21.5-1.10.11.01.3-0.71.0
Short access day 10 total locomotion0.80.92.61.30.30.11.0-0.90.21.21.6-0.51.0
Short access total locomotion0.80.82.41.00.40.11.0-0.80.31.31.5-0.51.1
Compulsive drug intake1.41.35.0-1.41.00.8-2.21.51.00.90.70.30.4
One hour access (0.3 mA shock)5.76.611.63.3-2.6-2.93.4-3.3-2.6-1.5-1.0-2.6-1.1
One hour access (shock baseline)5.26.014.02.9-2.5-2.53.7-3.0-2.5-2.0-1.5-1.6-1.2
Number of responses in last shaping day1.01.02.00.9-1.0-1.21.1-1.2-0.9-0.6-0.5-1.4-0.5
Context. condit. distance diff. score1.31.63.11.7-1.1-1.41.5-1.8-1.1-0.5-0.2-1.7-0.9
Locomotion velocity, session 10.20.20.50.3-0.3-0.5-0.4-0.2-0.3-0.10.1-0.7-0.7
Locomotion distance, session 11.72.24.9-0.41.61.5-1.10.91.72.12.20.81.5
Locomotion velocity, session 22.52.93.8-1.92.01.8-1.91.91.91.31.61.71.1
Locomotion distance, session 21.62.24.5-0.81.71.5-1.51.21.51.92.10.81.3
Locomotion velocity, session 30.10.20.50.30.50.30.2-0.20.40.60.7-0.10.3
Locomotion distance, session 30.00.00.10.1-0.0-0.20.1-0.1-0.00.2-0.0-0.2-0.1
Stereotopy head waving bouts, day 30.30.40.90.90.0-0.20.6-0.9-0.20.60.9-0.90.3
Stereotopy head waving duration, day 30.40.51.41.2-0.3-0.41.0-1.1-0.50.10.3-0.80.2
Locomotion velocity, session 70.30.31.40.40.70.40.4-0.40.40.41.2-0.10.5
Locomotion distance, session 70.20.31.3-0.00.70.3-0.4-0.10.40.51.1-0.40.4
Stereotopy head waving bouts, day 70.20.21.20.10.10.31.1-0.20.20.4-0.20.50.6
Stereotopy head waving duration, day 71.82.13.4-1.41.61.7-0.21.41.61.50.81.81.8
Locomotion velocity, session 80.50.61.8-0.90.60.6-1.41.00.60.80.50.30.3
Locomotion distance, session 80.10.20.60.80.1-0.10.3-0.6-0.00.30.7-0.4-0.2
Degree of sensitization distance0.40.41.3-0.10.70.6-0.40.10.60.71.1-0.00.7
Degree of sensitization stereotypy0.80.92.4-1.20.91.00.21.01.00.6-0.11.61.0
Condit. Reinf. active minus inactive responses0.40.40.9-0.50.70.7-0.50.60.81.00.70.60.5
Condit. Reinf. active-inactive response ratio0.10.10.4-0.00.20.3-0.10.30.30.60.20.30.2
Condit. Reinf. active responses0.20.20.3-0.60.60.6-0.30.40.50.50.60.60.1
Condit. Reinf. inactive responses0.00.10.1-0.30.30.30.1-0.00.1-0.10.40.3-0.1
Incentive salience index mean0.60.71.2-0.61.01.0-0.70.70.91.11.10.80.5
Condit. Reinf. lever presses0.20.30.6-0.60.60.6-0.60.60.40.20.30.8-0.2
Time in familiar zone, hab. session 10.10.10.40.60.10.10.6-0.30.10.30.20.00.3
Time in novel zone, hab. session 10.50.51.50.3-0.8-0.8-0.1-0.6-0.8-0.5-0.3-1.2-0.7
Total zone transitions, hab. session 10.81.11.5-1.11.21.2-1.21.11.21.01.01.00.6
Total locomotion distance, hab. session 10.10.20.50.5-0.2-0.20.4-0.7-0.3-0.10.3-0.5-0.4
Locomotion velocity, hab. session 10.00.00.20.00.20.1-0.1-0.20.10.10.5-0.1-0.1
Time in familiar zone, hab. session 20.20.20.9-0.2-0.3-0.5-0.6-0.2-0.30.00.1-1.0-0.3
Time in novel zone, hab. session 20.40.40.7-0.10.70.80.20.40.70.70.50.80.9
Total zone transitions, hab. session 24.86.212.2-1.32.72.8-1.31.72.83.53.01.72.9
Total locomotion distance, hab. session 20.91.23.80.01.11.0-0.10.01.11.91.80.11.2
Locomotion velocity, hab. session 20.70.92.90.31.00.80.2-0.10.91.71.60.11.1
Novel to familiar place preference ratio1.11.23.9-1.21.01.3-0.21.31.10.4-0.02.01.0
Novelty place preference0.70.72.4-0.70.71.00.20.90.80.3-0.11.60.9
Time in novel zone, NPP test0.50.51.7-0.70.70.90.20.70.70.3-0.01.30.9
Total zone transitions, NPP test2.43.54.6-1.42.12.1-1.81.92.21.91.91.81.5
Total locomotion distance, NPP test0.20.31.1-0.00.70.6-0.50.10.60.91.10.10.2
Locomotion velocity, NPP test0.20.30.9-0.00.70.6-0.50.20.60.70.90.30.1
Pavlov. Cond. lever latency0.20.30.40.5-0.7-0.70.4-0.5-0.5-0.5-0.3-0.6-0.3
Pavlov. Cond. magazine entry latency0.60.81.7-0.31.01.10.10.50.91.30.90.91.0
Pavlov. Cond. change in total contacts0.20.21.00.10.30.50.50.30.30.2-0.41.00.1
Pavlov. Cond. index score0.10.10.4-0.20.20.30.00.30.20.2-0.30.6-0.0
Pavlov. Cond. latency score0.00.10.2-0.10.30.30.10.20.20.40.00.40.1
Pavlov. Cond. lever contacts0.00.00.1-0.10.20.1-0.10.00.10.30.00.0-0.1
Pavlov. Cond. magazine entry number0.20.20.80.5-0.1-0.3-0.1-0.5-0.20.10.7-0.90.1
Pavlov. Cond. intertrial magazine entries0.40.50.90.3-0.9-0.80.6-0.5-0.8-1.0-0.9-0.3-0.7
Pavlov. Cond. lever-magazine prob. diff.0.20.20.7-0.40.50.6-0.20.50.40.3-0.10.80.1
Pavlov. Cond. response bias0.10.10.4-0.40.10.10.10.30.10.0-0.50.6-0.2
Bone: apparent density2.33.87.6-1.12.12.2-0.41.32.32.42.11.72.8
Bone surface5.59.615.4-2.93.23.7-1.73.33.52.62.03.93.4
Bone volume2.94.98.6-1.82.32.7-0.72.12.61.91.52.92.7
Bone: connectivity density4.77.410.8-2.02.93.1-1.42.43.13.02.62.83.3
Bone: cortical apparent density0.10.10.5-0.30.30.1-0.70.40.20.30.20.0-0.1
Bone: cortical area0.40.61.5-1.20.50.5-0.91.10.4-0.6-0.31.2-0.3
Bone: cortical porosity0.60.71.6-0.10.90.9-0.30.40.80.91.30.51.1
Bone: cortical porosity1.01.11.8-0.71.21.3-0.80.81.11.11.30.81.2
Bone: cortical thickness1.32.27.0-2.70.90.6-2.62.10.8-0.2-0.11.2-0.6
Bone: cortical thickness0.40.52.2-1.00.1-0.4-1.50.70.1-0.2-0.2-0.2-0.7
Bone: cortical tissue density0.10.10.7-0.40.30.2-0.80.50.20.30.20.1-0.1
Bone: elastic displacement1.82.14.01.1-1.6-1.90.2-1.2-1.7-1.1-1.0-2.0-1.7
Bone: elastic work0.40.52.8-0.80.3-0.1-1.70.80.20.00.2-0.2-0.6
Bone: endosteal estimation0.30.72.61.4-0.10.01.6-1.2-0.30.20.7-0.40.6
Bone: endosteal perimeter0.51.14.71.9-0.20.32.2-1.1-0.10.20.50.30.9
Bone: final force1.93.14.9-2.11.82.0-1.92.21.80.81.12.21.0
Bone: final moment1.72.84.3-2.01.71.9-1.82.11.70.81.02.01.0
Bone: marrow area0.40.82.61.5-0.10.01.6-1.2-0.30.30.8-0.50.6
Bone: maximum diameter0.20.31.2-0.2-0.10.40.20.5-0.0-0.7-0.81.1-0.2
Bone: maximum force3.66.210.1-2.42.83.0-1.92.72.71.81.93.22.1
Bone: maximum moment3.15.38.5-2.22.62.8-1.72.52.51.71.82.92.0
Bone: minimum diameter0.40.82.01.00.60.51.4-0.80.30.81.30.11.2
Bone: periosteal estimation0.00.10.4-0.00.20.30.5-0.0-0.0-0.40.00.60.1
Bone: periosteal perimeter0.20.41.5-0.20.60.90.20.50.60.20.31.20.8
Bone: post-yield work4.15.69.9-0.52.73.20.51.22.52.72.52.93.0
Bone: stiffness3.35.29.1-2.22.52.8-1.32.42.51.71.73.02.1
Bone: tissue strength0.20.20.5-0.20.30.60.10.30.30.30.10.70.4
Bone: trabecular number2.23.47.0-1.21.92.1-0.31.52.12.01.52.12.6
Bone: trabecular spacing0.60.71.71.1-0.7-1.10.1-0.8-0.9-0.5-0.2-1.3-1.1
Bone: trabecular thickness0.40.51.50.30.50.50.8-0.30.60.90.70.21.2
Bone: trabecular tissue density4.05.68.32.6-2.5-2.32.3-2.6-2.9-2.2-1.6-2.2-2.3
Breakpoint value in progressive ratio session2.42.75.9-2.01.51.8-1.62.21.70.50.22.40.8
Distance traveled before self-admin0.30.30.9-0.60.50.6-0.30.70.50.0-0.00.90.3
Distance traveled after self-admin0.20.20.9-0.60.20.5-0.00.50.2-0.3-0.30.90.1
Delta time in closed arm before/after self-admin0.40.41.0-0.80.3-0.0-1.00.10.20.51.0-0.8-0.1
Delta time in open arm before/after self-admin0.40.41.8-0.3-0.3-0.00.70.2-0.2-0.7-1.30.8-0.1
Diff in mean of infusions in LGA sessions0.30.31.3-1.10.10.3-0.30.70.3-0.3-0.60.8-0.1
Extinction: sum of active levers before priming4.34.37.3-2.12.32.4-1.92.52.31.41.22.71.4
Active lever presses in extinction session 61.31.23.4-1.90.40.8-1.11.50.5-0.7-0.91.7-0.3
Delta distance traveled before/after self-admin0.00.00.0-0.0-0.2-0.10.1-0.1-0.2-0.2-0.2-0.1-0.2
Delta ambulatory time before/after self-admin0.00.00.0-0.1-0.1-0.1-0.2-0.0-0.1-0.10.0-0.2-0.2
Time in closed arm before self-admin0.10.10.40.20.10.40.50.20.20.1-0.40.60.3
Time in closed arm after self-admin0.10.10.4-0.20.20.1-0.2-0.00.00.40.6-0.2-0.0
Time in open arm before self-admin0.60.63.30.5-0.2-0.8-0.4-0.8-0.40.41.0-1.8-0.3
Time in open arm after self-admin0.40.51.10.1-0.8-0.80.5-0.5-0.7-0.6-1.1-0.8-0.5
Sum of active levers in priming session hrs 5-61.61.53.8-1.3-0.50.1-0.61.2-0.2-1.8-2.01.8-1.2
Time to tail flick, vehicle, before self-admin0.90.91.2-0.81.01.0-0.80.81.01.11.00.90.9
Time to tail flick, vehicle, after self-admin2.02.23.2-1.31.71.4-1.61.21.61.81.80.61.3
Time to tail flick, test, before self-admin0.80.83.20.60.50.20.2-0.60.51.31.8-1.00.8
Time to tail flick, test, after self-admin0.00.00.1-0.2-0.20.0-0.30.1-0.10.1-0.10.0-0.2
Delta time to tail flick, vehicle, before/after SA0.80.71.0-0.81.00.8-0.80.71.01.01.00.40.9
Delta time to tail flick, test, before/after SA1.11.02.9-1.2-0.5-0.2-0.90.9-0.5-1.2-1.70.8-1.0
Ambulatory time before self-admin0.40.41.7-0.80.40.7-0.00.70.4-0.1-0.61.30.3
Ambulatory time after self-admin0.20.20.9-0.00.10.50.80.00.1-0.2-0.20.90.4
Total heroin consumption3.34.07.2-2.22.12.3-2.12.72.21.30.42.51.1
Area under the delay curve0.60.62.00.70.50.40.1-0.20.61.21.4-0.40.9
Delay disc. indifference point, 0s delay0.91.03.31.30.2-0.30.1-0.90.11.11.8-1.50.6
Delay disc. indifference point, 16s delay0.40.41.61.2-0.3-0.11.2-0.7-0.20.40.2-0.20.3
Delay disc. indifference point, 2s delay0.10.10.30.5-0.1-0.20.4-0.30.20.10.2-0.40.3
Delay disc. indifference point, 24s delay0.20.20.90.3-0.3-0.4-0.2-0.4-0.40.30.5-1.0-0.4
Delay disc. indifference point, 4s delay0.50.51.50.70.3-0.00.0-0.40.41.01.2-1.00.7
Delay disc. indifference point, 8s delay0.50.52.00.70.40.1-0.3-0.20.41.01.4-0.80.6
Delay discount exponential model param0.40.51.7-0.6-0.5-0.30.10.2-0.5-1.1-1.30.4-0.8
Delay discount hyperbolic model param0.40.41.5-0.6-0.5-0.30.10.1-0.6-1.0-1.20.4-0.8
Fecal boli incidents, locomotor time 10.30.31.1-0.3-0.20.20.60.3-0.1-0.4-1.11.0-0.1
Change in fecal boli incidents, locomotor task0.60.62.30.10.60.3-0.80.00.51.11.5-0.60.5
Time >=10cm from walls, locomotor time 10.40.41.00.60.30.61.0-0.50.10.60.80.50.8
Bouts of movement, locomotor time 10.80.81.9-1.10.71.0-0.91.30.80.5-0.11.40.5
Total resting periods, locomotor time 10.70.72.0-0.90.71.0-0.61.20.70.5-0.11.40.6
Rest time, locomotor task time 11.82.02.71.4-1.6-1.51.4-1.4-1.6-1.3-1.3-1.2-1.3
Distance moved, locomotor task time 10.80.92.0-0.51.10.9-0.60.61.11.01.40.61.2
Vertical activity count, locomotor time 10.70.71.31.0-0.8-1.10.8-1.1-0.9-0.6-0.3-1.0-0.6
Time >=10cm from walls, locomotor time 20.00.00.10.2-0.00.30.2-0.0-0.2-0.0-0.20.3-0.2
Bouts of movement, locomotor time 20.60.61.1-1.10.80.8-0.71.00.70.60.51.00.8
Total resting periods, locomotor time 20.40.50.8-0.80.70.7-0.40.70.50.50.50.90.8
Rest time, locomotor task time 21.82.03.51.8-1.4-1.51.6-1.9-1.6-0.9-0.4-1.7-0.8
Distance moved, locomotor task time 20.70.81.9-1.10.80.8-1.41.20.90.30.30.90.3
Vertical activity count, locomotor time 20.60.61.60.1-0.8-1.0-0.6-0.2-0.7-0.9-0.8-0.8-1.3
Weight adjusted by age1.82.04.4-1.91.11.3-2.11.81.30.30.41.80.4
Seeking ratio, delayed vs. immediate footshock0.30.41.30.10.60.5-0.30.10.60.91.10.10.8
Locomotion in novel chamber3.94.87.12.7-2.3-2.32.6-2.6-2.3-2.1-1.4-1.7-1.7
Locomotion in novel chamber post-restriction2.32.75.11.9-1.7-1.82.3-2.0-1.5-1.3-1.0-1.7-1.0
Progressive ratio4.24.96.7-1.62.62.5-1.21.82.62.52.41.92.6
Food seeking constrained by brief footshock0.20.31.2-0.70.40.2-1.10.50.40.40.6-0.10.2
Seeking ratio, punishment vs. effort2.83.45.11.6-2.1-2.30.5-1.7-2.2-1.8-1.4-2.2-2.1
Run reversals in cocaine runway, females2.12.15.5-0.41.71.3-1.50.71.52.02.40.11.3
Run reversals in cocaine runway, males2.01.93.80.1-1.5-1.60.1-0.8-1.5-1.8-1.6-1.2-2.0
Latency to leave start box in cocaine runway0.40.40.80.00.70.70.60.20.70.90.80.60.8
Latency to leave start box in cocaine runway, F0.20.30.50.00.60.60.30.20.60.70.70.30.6
Latency to leave start box in cocaine runway, M0.00.00.2-0.10.20.20.20.20.10.00.10.40.1
Cd content in liver1.82.03.21.0-1.7-1.41.5-1.3-1.6-1.8-1.5-0.8-1.1
Co content in liver2.12.55.71.2-1.7-1.90.6-1.7-1.7-1.4-0.8-2.4-1.5
Cu content in liver0.40.40.8-0.50.90.6-0.60.70.90.30.50.80.6
Fe content in liver0.10.10.2-0.40.00.1-0.20.40.1-0.3-0.30.4-0.1
K content in liver2.92.94.1-1.12.01.9-1.31.62.01.71.71.61.7
Mg content in liver2.22.34.7-0.11.81.7-0.20.71.82.11.91.12.2
Mn content in liver2.22.65.5-1.81.51.8-1.22.11.61.10.52.41.1
Na content in liver0.40.41.0-0.40.20.3-0.80.90.3-0.6-0.51.0-0.6
Rb content in liver0.50.71.41.1-0.0-0.31.2-1.1-0.10.50.8-0.90.9
Se content in liver0.40.51.7-0.20.40.90.60.50.70.3-0.11.31.1
Sr content in liver1.21.13.4-1.80.40.7-1.31.60.5-0.5-0.81.3-0.1
Zn content in liver1.11.21.8-1.11.21.3-1.11.31.20.70.41.30.7