Brms1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression ENSRNOG00000020117 0.46 0.17 5.4e-07 0.05 0.08 0.09 0.04 2.7e-05 4.3e-08 6.7e-09 6.3e-05
2 Brain mRNA stability ENSRNOG00000020117 0.05 0.05 7.8e-04 0.02 0.03 0.03 0.01 4.9e-03 1.4e-03 3.7e-04 6.8e-02
3 Liver mRNA stability ENSRNOG00000020117 0.04 0.03 3.6e-04 0.01 0.02 0.01 0.01 3.7e-02 4.8e-03 7.5e-03 1.7e-02
4 NAcc gene expression ENSRNOG00000020117 0.21 0.12 1.5e-06 0.06 0.08 0.08 0.08 5.0e-05 1.7e-06 2.6e-06 1.2e-06
5 NAcc intron excision ratio chr1:202350812:202350918 0.04 0.04 5.8e-03 0.02 0.02 0.01 0.02 1.9e-02 1.2e-02 8.6e-02 2.0e-02
6 NAcc mRNA stability ENSRNOG00000020117 0.03 0.02 9.8e-03 0.04 0.02 0.02 0.04 4.5e-04 6.7e-03 1.0e-02 8.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6
BMI with tail2.06.416.2-1.11.04.0-3.6-0.42.6
BMI without tail0.71.53.80.00.61.9-1.6-0.31.4
Body weight2.29.218.60.73.34.3-2.22.43.9
Epididymis fat weight1.94.57.7-1.4-2.8-2.30.4-2.5-2.5
Glucose1.93.06.4-1.4-2.2-1.1-0.9-2.5-1.7
Heart weight1.72.44.3-0.6-1.9-1.90.3-2.1-1.6
Left kidney weight0.51.42.4-0.7-1.5-1.61.0-0.4-1.3
Right kidney weight0.20.71.3-1.2-0.9-0.90.70.6-0.6
Tail length1.13.46.32.32.20.31.72.51.1
Length with tail1.86.711.81.93.42.20.23.42.9
Length without tail1.83.96.20.62.52.4-0.92.22.3
Liver weight, left0.10.20.60.3-0.2-0.60.8-0.0-0.4
Liver weight, right0.20.40.90.90.1-0.50.9-0.1-0.6
Parametrial fat weight2.24.27.5-1.8-2.7-1.7-0.3-2.6-2.2
Retroperitoneal fat weight3.712.421.8-1.8-4.4-3.90.8-3.8-4.7
Intraocular pressure0.60.81.8-1.1-1.1-1.30.80.1-0.4
Extensor digitorum longus weight4.718.833.81.54.95.5-1.84.45.8
Soleus weight3.19.118.40.2-3.1-3.92.4-2.3-4.3
Tibialis anterior weight7.325.141.12.46.05.4-0.76.16.4
Tibia length0.61.84.7-0.81.11.4-0.22.21.4
Number of licking bursts0.20.30.5-0.40.50.7-0.50.30.5
Food consumed during 24 hour testing period0.10.10.3-0.10.1-0.10.10.60.1
Times rat made contact with spout0.40.40.90.10.70.9-0.80.00.6
Mean time between licks in bursts0.71.02.51.61.50.50.60.60.4
Mean num. licks in bursts0.10.10.40.2-0.3-0.40.0-0.6-0.4
Std. dev. time between licks in bursts1.21.54.22.00.8-0.81.80.5-0.2
Water consumed over 24 hours0.50.61.20.11.11.0-0.60.61.0
Indifference point 0 sec0.10.20.5-0.7-0.3-0.0-0.5-0.5-0.4
Indifference point AUC2.42.95.9-0.21.82.0-0.81.82.4
Indifference point function ln k5.78.115.40.9-2.7-3.72.4-2.4-3.9
Indifference point function log k5.78.115.40.9-2.7-3.72.4-2.4-3.9
Delay discounting total patch changes 0 sec0.00.00.10.00.1-0.20.1-0.0-0.3
Delay discounting total patch changes 12 sec3.14.17.9-0.22.22.8-1.61.62.6
Delay discounting total patch changes 18 sec0.70.91.7-1.00.41.1-1.20.21.3
Delay discounting total patch changes 24 sec1.51.93.50.31.91.6-0.41.61.7
Delay discounting total patch changes 6 sec0.91.42.8-0.11.21.7-1.30.51.5
Delay discounting time to switch 0 sec2.03.07.2-1.20.62.5-2.7-0.01.7
Delay discounting water rate 0 sec3.14.911.20.5-1.6-3.42.9-0.5-2.7
Delay discounting water rate 12 sec6.69.921.21.7-1.9-4.63.8-1.4-3.9
Delay discounting water rate 18 sec2.63.46.61.2-1.2-2.51.9-1.1-2.6
Delay discounting water rate 24 sec3.54.810.51.1-1.4-3.22.8-0.8-2.6
Delay discounting water rate 6 sec3.24.69.41.8-0.9-3.12.9-0.5-2.4
Locomotor activity1.52.44.71.3-0.3-2.22.1-0.3-1.8
Locomotor testing distance2.23.66.61.8-0.3-2.62.5-0.6-2.3
Locomotor testing rearing1.21.93.80.7-0.7-2.01.1-1.5-1.8
Light reinforcement 10.10.20.50.1-0.1-0.70.6-0.3-0.7
Light reinforcement 20.81.11.8-1.3-1.4-1.10.2-0.5-1.2
Reaction time number correct0.40.61.40.60.90.30.51.20.8
Reaction time mean minus median2.33.05.5-1.11.32.3-1.71.42.3
Reaction time mean minus median AUC1.31.63.4-0.21.21.4-0.51.61.8
Reaction time num false alarms1.21.64.82.20.5-0.91.80.4-0.5
Reaction time num false alarms AUC1.11.55.12.31.1-0.21.40.90.3
Reaction time trials correct on left0.40.61.40.60.90.30.51.20.8
Reaction time trials on left0.50.71.80.61.00.30.61.30.9
Reaction time mean0.10.10.5-0.7-0.30.2-0.40.10.3
Reaction time mean AUC0.20.20.7-0.9-0.50.2-0.5-0.10.1
Median of all reaction times0.10.20.5-0.6-0.7-0.2-0.2-0.4-0.2
Reaction time omissions1.01.42.70.31.11.4-0.51.41.7
Reaction time false alarm rate0.60.93.31.80.3-0.61.20.2-0.4
Reaction time premature initiation rate1.92.55.51.92.31.30.11.61.3
Reaction time premature initiations3.24.59.32.23.01.70.42.52.0
Std. dev. reaction times0.70.91.6-0.80.51.2-0.90.81.3
Reaction time trials completed0.50.71.80.61.00.30.61.30.9
Reaction time trials AUC0.40.51.20.60.90.20.61.10.7
Social response proportion0.80.92.4-0.70.71.3-1.50.20.5
Social responses0.20.20.70.30.80.5-0.30.50.3
Social time0.40.51.20.91.10.4-0.00.70.6
Conditioned locomotion1.51.82.91.21.71.00.41.71.5
Cocaine response after cond. corrected0.80.91.80.6-0.7-1.31.0-0.9-1.1
Cocaine response after cond. not corrected0.60.71.10.4-0.7-1.10.5-1.0-1.0
Cocaine response before conditioning0.60.71.3-0.80.41.1-1.20.40.9
Saline control response2.43.15.70.72.32.4-1.11.42.0
Condit. Reinf. active minus inactive responses0.91.13.2-1.8-0.90.1-1.1-0.9-0.5
Condit. Reinf. active-inactive response ratio1.41.54.0-2.0-1.5-0.4-0.7-1.0-1.0
Condit. Reinf. active responses0.91.33.3-1.7-0.40.8-1.8-1.00.1
Condit. Reinf. inactive responses0.70.92.5-0.30.51.2-1.6-0.70.8
Condit. Reinf. lever presses1.92.75.2-1.21.02.3-2.00.91.9
Condit. Reinf. lever reinforcers received0.91.33.6-1.6-0.11.1-1.9-0.60.4
Pavlov. Cond. lever latency0.50.61.10.8-0.3-1.11.0-0.5-0.8
Pavlov. Cond. magazine entry latency2.73.17.0-0.51.52.6-2.00.92.1
Pavlov. Cond. change in total contacts2.12.95.7-2.00.32.3-2.40.61.5
Pavlov. Cond. index score1.82.45.3-1.00.92.3-1.90.91.6
Pavlov. Cond. latency score1.51.94.3-1.00.72.1-1.70.91.4
Pavlov. Cond. lever contacts0.30.50.7-0.40.50.9-0.60.80.7
Pavlov. Cond. magazine entry number4.55.511.90.8-2.0-3.42.6-1.5-2.8
Pavlov. Cond. intertrial magazine entries0.81.02.1-0.3-1.2-1.40.7-0.8-1.2
Pavlov. Cond. lever-magazine prob. diff.2.22.86.2-0.91.12.5-2.01.01.9
Pavlov. Cond. response bias1.31.83.6-0.71.01.9-1.51.01.5
Conditioned reinforcement - actives0.20.20.4-0.6-0.5-0.50.30.0-0.5
Conditioned reinforcement - inactives3.94.47.0-1.9-2.6-2.50.8-1.8-2.4
Conditioned locomotion5.66.712.5-0.6-2.7-3.52.2-1.7-3.4
Intermittent access intake day 1-15 change0.40.40.9-0.5-0.5-0.90.60.3-0.7
Intermittent access intake escalation0.30.30.6-0.6-0.6-0.80.40.0-0.7
Intermittent access intake escalation 20.30.30.6-0.4-0.2-0.70.80.6-0.3
Intermitt. access day 1 inactive lever presses1.51.73.4-1.1-1.8-1.3-0.0-1.3-1.4
Intermitt. access day 15 inactive lever presses1.61.83.3-1.7-1.8-1.2-0.2-1.0-1.4
Intermitt. access escalation Index2.92.64.70.1-1.8-1.60.5-2.2-2.1
Intermittent access day 1 total infusions5.25.912.5-2.1-3.2-1.5-1.1-3.5-2.2
Intermittent access day 15 total infusions5.56.111.0-2.2-3.3-2.40.0-2.8-2.7
Intermittent access terminal intake (last 3 days)4.34.79.1-2.3-3.0-1.8-0.4-2.5-2.1
Intermittent access total infusions4.14.58.3-2.2-2.9-1.3-1.0-2.8-1.9
Intermittent access day 1 locomotion3.53.68.9-1.3-2.6-0.9-1.0-3.0-1.6
Intermittent access day 15 total locomotion3.63.87.0-1.9-2.6-1.7-0.2-2.3-2.1
Intermittent access total locomotion6.16.912.3-2.7-3.5-1.6-1.1-3.4-2.5
Intermittent access standard deviation0.60.61.4-0.4-0.9-1.20.6-0.4-0.8
Cocaine induced anxiety0.00.00.1-0.30.0-0.10.10.30.1
Post-drug Anxiety1.11.22.7-0.11.30.9-0.01.71.4
Baseline Anxiety1.81.93.20.61.81.4-0.11.81.6
Lifetime Intake3.53.97.7-1.9-2.7-1.2-1.0-2.8-1.7
Incentive Sensitization - Responses0.70.71.7-1.3-1.0-0.2-0.7-0.7-0.5
Incentive Sensitization - Breakpoint0.80.81.7-1.3-1.2-0.4-0.5-0.8-0.7
Progressive ratio test 1 active lever presses1.81.93.4-0.8-1.9-1.40.2-1.6-1.5
Progressive ratio test 1 breakpoint1.51.52.8-0.7-1.7-1.40.3-1.4-1.4
Progressive ratio test 1 inactive lever presses0.80.81.6-0.4-1.1-0.9-0.1-1.3-1.0
Progressive ratio test 2 active lever presses3.03.26.0-1.7-2.4-1.6-0.2-2.0-1.9
Progressive ratio test 2 breakpoint3.23.66.3-1.4-2.5-2.20.5-1.9-2.3
Progressive ratio test 2 inactive lever presses6.27.212.0-2.4-3.5-2.60.0-3.2-2.9
Total sessions with >9 infusions1.21.43.1-0.6-1.7-0.8-0.4-1.8-1.1
Short access day 1 total inactive lever presses2.62.95.0-1.0-2.2-1.80.5-2.0-1.9
Short access day 10 total inactive lever presses1.92.13.90.2-1.6-2.00.9-1.4-1.9
Short access day 1 total infusions3.13.37.0-1.3-2.6-1.0-0.8-2.6-1.6
Short access day 10 total infusions3.03.37.3-2.0-2.10.1-2.0-2.7-0.6
Short access total infusions1.61.84.6-1.0-1.8-0.4-1.0-2.1-0.8
Short access day 1 locomotion2.42.55.5-1.2-2.1-0.7-1.1-2.3-1.3
Short access day 10 total locomotion1.81.94.7-1.0-1.7-0.4-1.0-2.2-1.3
Short access total locomotion1.61.64.2-0.9-1.6-0.3-1.0-2.0-1.0
Compulsive drug intake2.82.85.12.22.31.10.61.71.4
One hour access (0.3 mA shock)6.17.111.7-1.3-3.4-3.10.7-2.9-3.3
One hour access (shock baseline)6.17.113.0-2.5-3.6-2.70.1-2.7-2.9
Number of responses in last shaping day0.70.71.60.5-0.8-1.30.9-0.6-0.9
Context. condit. distance diff. score1.31.62.8-0.1-1.4-1.60.7-1.3-1.7
Locomotion velocity, session 10.40.41.11.00.5-0.31.00.4-0.3
Locomotion distance, session 10.50.61.5-0.20.41.2-1.2-0.50.4
Locomotion velocity, session 21.61.94.00.31.42.0-0.91.01.9
Locomotion distance, session 20.50.71.80.40.71.4-0.90.00.8
Locomotion velocity, session 30.20.20.5-0.3-0.60.1-0.5-0.7-0.3
Locomotion distance, session 30.00.00.0-0.0-0.1-0.1-0.1-0.1-0.1
Stereotopy head waving bouts, day 30.50.71.8-0.1-0.9-0.6-0.2-1.3-0.9
Stereotopy head waving duration, day 30.81.02.1-0.6-1.2-0.8-0.2-1.4-1.2
Locomotion velocity, session 70.60.71.5-0.8-1.20.0-0.6-1.2-0.4
Locomotion distance, session 70.00.10.20.4-0.10.10.1-0.40.0
Stereotopy head waving bouts, day 70.91.12.7-1.6-1.10.1-1.3-1.0-0.1
Stereotopy head waving duration, day 71.72.05.1-1.60.11.6-2.3-0.21.4
Locomotion velocity, session 80.81.02.31.01.50.80.21.10.9
Locomotion distance, session 80.20.30.6-0.3-0.7-0.3-0.0-0.8-0.8
Degree of sensitization distance0.10.10.30.2-0.10.3-0.2-0.50.1
Degree of sensitization stereotypy1.21.32.6-1.6-0.11.1-1.60.11.2
Condit. Reinf. active minus inactive responses0.20.20.6-0.20.20.7-0.8-0.00.5
Condit. Reinf. active-inactive response ratio0.10.10.4-0.4-0.00.3-0.7-0.10.0
Condit. Reinf. active responses0.10.20.3-0.3-0.00.6-0.60.00.6
Condit. Reinf. inactive responses0.10.10.2-0.3-0.40.2-0.2-0.20.3
Incentive salience index mean0.30.40.9-0.20.21.0-0.9-0.00.6
Condit. Reinf. lever presses0.20.20.6-0.10.30.8-0.40.50.6
Time in familiar zone, hab. session 10.50.40.7-0.8-0.7-0.1-0.6-0.8-0.6
Time in novel zone, hab. session 10.80.81.91.40.4-0.91.30.2-0.3
Total zone transitions, hab. session 10.50.71.50.10.81.2-0.70.61.1
Total locomotion distance, hab. session 10.20.30.7-0.1-0.9-0.50.1-0.7-0.5
Locomotion velocity, hab. session 10.00.00.20.0-0.4-0.0-0.1-0.3-0.0
Time in familiar zone, hab. session 20.70.72.41.50.7-0.41.10.50.2
Time in novel zone, hab. session 20.60.61.5-1.2-0.40.6-1.2-0.60.1
Total zone transitions, hab. session 22.02.66.8-1.10.52.2-2.6-0.91.3
Total locomotion distance, hab. session 20.50.71.8-0.6-0.60.5-1.2-1.4-0.0
Locomotion velocity, hab. session 20.70.92.2-0.9-0.90.3-1.2-1.5-0.3
Novel to familiar place preference ratio1.21.32.3-1.40.11.4-1.50.31.2
Novelty place preference0.91.02.2-1.5-0.21.0-1.4-0.00.7
Time in novel zone, NPP test0.70.71.6-1.3-0.20.9-1.3-0.10.7
Total zone transitions, NPP test1.21.74.3-0.31.22.1-1.40.51.4
Total locomotion distance, NPP test0.10.10.20.1-0.10.4-0.4-0.40.0
Locomotion velocity, NPP test0.10.10.2-0.0-0.10.5-0.4-0.20.0
Pavlov. Cond. lever latency0.10.20.40.2-0.1-0.60.5-0.1-0.5
Pavlov. Cond. magazine entry latency0.71.02.2-1.4-0.50.8-1.5-0.70.3
Pavlov. Cond. change in total contacts0.80.82.8-1.7-0.80.5-1.1-0.3-0.1
Pavlov. Cond. index score0.10.20.5-0.7-0.20.4-0.50.10.2
Pavlov. Cond. latency score0.10.10.4-0.6-0.30.3-0.5-0.10.1
Pavlov. Cond. lever contacts0.00.00.0-0.0-0.10.1-0.1-0.00.1
Pavlov. Cond. magazine entry number0.20.30.70.90.0-0.50.5-0.4-0.5
Pavlov. Cond. intertrial magazine entries0.10.20.4-0.2-0.4-0.70.50.1-0.3
Pavlov. Cond. lever-magazine prob. diff.0.20.30.5-0.7-0.00.7-0.60.20.4
Pavlov. Cond. response bias0.10.10.4-0.6-0.10.3-0.40.30.4
Bone: apparent density1.52.56.7-1.6-0.11.7-2.6-1.21.1
Bone surface3.76.512.3-2.11.53.5-3.40.52.9
Bone volume2.33.88.8-2.30.32.4-3.0-0.41.8
Bone: connectivity density2.54.08.7-1.60.92.7-2.9-0.32.0
Bone: cortical apparent density0.20.30.50.70.70.30.20.70.3
Bone: cortical area0.50.81.9-0.00.80.9-0.01.41.2
Bone: cortical porosity0.30.31.0-0.30.00.6-1.0-0.60.1
Bone: cortical porosity0.40.40.9-0.00.61.0-0.9-0.10.7
Bone: cortical thickness3.25.39.92.02.71.60.93.12.7
Bone: cortical thickness1.82.14.22.11.60.31.31.81.0
Bone: cortical tissue density0.30.40.60.80.80.40.30.80.4
Bone: elastic displacement1.71.94.91.70.2-1.62.20.5-1.1
Bone: elastic work1.52.03.61.91.70.41.31.70.8
Bone: endosteal estimation1.22.65.1-1.7-2.0-0.7-1.0-2.3-1.4
Bone: endosteal perimeter2.44.99.1-3.0-2.5-0.6-1.8-2.7-1.9
Bone: final force1.62.64.80.01.72.2-1.01.52.1
Bone: final moment1.42.34.30.01.62.1-1.01.42.0
Bone: marrow area1.22.75.4-1.7-2.1-0.7-1.0-2.3-1.5
Bone: maximum diameter0.20.31.1-1.0-0.00.4-0.40.50.2
Bone: maximum force2.44.19.0-1.31.33.0-2.50.82.4
Bone: maximum moment2.03.57.7-1.21.22.8-2.30.72.2
Bone: minimum diameter1.62.95.3-2.0-2.1-0.2-1.6-2.3-1.0
Bone: periosteal estimation0.20.41.2-1.1-0.70.2-0.6-0.40.0
Bone: periosteal perimeter0.40.72.1-1.4-0.30.7-1.2-0.30.2
Bone: post-yield work5.98.018.5-4.1-1.72.2-4.3-2.30.5
Bone: stiffness2.43.77.2-1.70.92.7-2.60.42.2
Bone: tissue strength0.30.31.0-1.0-0.10.4-0.8-0.20.2
Bone: trabecular number1.82.77.0-2.0-0.01.8-2.7-0.81.2
Bone: trabecular spacing0.60.71.31.0-0.1-0.91.20.0-1.1
Bone: trabecular thickness0.91.12.3-1.3-1.00.0-1.4-1.5-0.3
Bone: trabecular tissue density2.53.56.8-0.3-2.0-2.61.5-1.1-2.6
Breakpoint value in progressive ratio session2.22.54.4-0.31.52.1-1.11.62.0
Distance traveled before self-admin0.30.30.5-0.60.40.7-0.50.40.6
Distance traveled after self-admin0.20.30.7-0.80.10.5-0.30.30.6
Delta time in closed arm before/after self-admin0.90.82.61.61.0-0.10.80.40.8
Delta time in open arm before/after self-admin0.30.31.1-1.1-0.30.1-0.30.30.3
Diff in mean of infusions in LGA sessions0.50.51.3-0.20.60.6-0.21.01.1
Extinction: sum of active levers before priming3.03.06.8-0.51.32.6-1.81.32.1
Active lever presses in extinction session 61.91.94.00.11.51.20.02.01.9
Delta distance traveled before/after self-admin0.00.00.1-0.00.0-0.10.20.10.0
Delta ambulatory time before/after self-admin0.10.10.10.30.3-0.10.40.20.1
Time in closed arm before self-admin0.20.30.9-0.9-0.50.3-0.6-0.3-0.2
Time in closed arm after self-admin0.00.00.00.20.00.00.0-0.10.2
Time in open arm before self-admin0.90.93.11.80.1-0.91.0-0.5-0.5
Time in open arm after self-admin0.20.30.70.6-0.1-0.70.80.1-0.1
Sum of active levers in priming session hrs 5-61.61.55.2-0.61.10.80.32.31.3
Time to tail flick, vehicle, before self-admin0.40.40.9-0.30.50.9-0.9-0.00.8
Time to tail flick, vehicle, after self-admin1.01.11.90.81.11.4-0.90.31.3
Time to tail flick, test, before self-admin0.60.62.40.2-0.8-0.3-0.4-1.5-0.6
Time to tail flick, test, after self-admin0.00.00.10.10.4-0.00.00.20.2
Delta time to tail flick, vehicle, before/after SA0.40.40.70.50.50.8-0.70.10.8
Delta time to tail flick, test, before/after SA1.71.54.10.51.60.30.72.01.2
Ambulatory time before self-admin0.60.61.4-1.20.10.8-1.00.40.8
Ambulatory time after self-admin0.91.03.7-1.9-0.90.3-1.0-0.70.0
Total heroin consumption3.03.66.70.32.02.6-1.12.12.2
Area under the delay curve0.40.41.20.0-0.50.0-0.5-1.1-0.7
Delay disc. indifference point, 0s delay0.80.92.20.7-0.6-0.70.2-1.5-1.3
Delay disc. indifference point, 16s delay1.31.32.2-1.3-1.5-0.5-0.8-1.4-1.2
Delay disc. indifference point, 2s delay0.10.20.4-0.1-0.5-0.20.0-0.6-0.5
Delay disc. indifference point, 24s delay0.30.31.11.00.3-0.50.6-0.0-0.3
Delay disc. indifference point, 4s delay0.30.30.90.7-0.3-0.30.0-1.0-0.7
Delay disc. indifference point, 8s delay0.30.30.60.7-0.0-0.1-0.1-0.8-0.7
Delay discount exponential model param0.30.30.9-0.10.3-0.00.40.90.6
Delay discount hyperbolic model param0.20.20.7-0.20.3-0.00.40.90.6
Fecal boli incidents, locomotor time 10.40.52.0-1.4-0.40.2-0.60.30.3
Change in fecal boli incidents, locomotor task0.20.20.70.80.50.10.0-0.5-0.1
Time >=10cm from walls, locomotor time 12.22.34.9-2.2-1.6-0.0-1.5-1.8-0.6
Bouts of movement, locomotor time 10.91.01.5-0.21.01.2-1.01.01.1
Total resting periods, locomotor time 10.70.81.3-0.60.71.2-1.10.70.9
Rest time, locomotor task time 11.01.12.1-0.0-1.0-1.51.1-0.5-1.4
Distance moved, locomotor task time 10.30.40.7-0.50.10.8-0.9-0.50.5
Vertical activity count, locomotor time 10.60.61.2-0.2-0.9-1.10.4-0.8-1.0
Time >=10cm from walls, locomotor time 20.10.10.5-0.7-0.40.1-0.4-0.2-0.2
Bouts of movement, locomotor time 20.50.51.1-0.10.70.9-0.70.51.1
Total resting periods, locomotor time 20.30.30.7-0.30.30.7-0.70.20.8
Rest time, locomotor task time 21.61.93.1-0.2-1.6-1.80.7-1.4-1.8
Distance moved, locomotor task time 20.80.91.70.41.31.1-0.31.11.1
Vertical activity count, locomotor time 21.01.12.31.51.0-0.61.31.1-0.1
Weight adjusted by age1.92.13.80.11.81.6-0.51.71.9
Seeking ratio, delayed vs. immediate footshock0.20.20.6-0.3-0.10.3-0.8-0.8-0.1
Locomotion in novel chamber3.44.27.1-1.4-2.5-2.40.9-1.8-2.7
Locomotion in novel chamber post-restriction2.02.33.8-0.6-1.9-1.90.9-1.4-1.9
Progressive ratio2.12.45.6-0.90.52.2-2.4-0.41.6
Food seeking constrained by brief footshock0.40.50.91.01.00.30.30.60.7
Seeking ratio, punishment vs. effort2.02.45.41.6-0.2-2.02.30.2-1.6
Run reversals in cocaine runway, females0.50.51.10.70.51.0-0.9-0.40.4
Run reversals in cocaine runway, males1.51.54.01.30.5-1.22.01.1-0.1
Latency to leave start box in cocaine runway0.60.71.3-1.0-0.80.5-1.1-0.8-0.0
Latency to leave start box in cocaine runway, F0.20.30.6-0.6-0.50.4-0.8-0.5-0.0
Latency to leave start box in cocaine runway, M0.10.10.2-0.4-0.20.2-0.3-0.10.1
Cd content in liver0.90.92.2-0.7-1.1-1.50.9-0.4-1.0
Co content in liver2.22.66.02.0-0.1-2.02.5-0.0-1.2
Cu content in liver0.20.20.7-0.00.20.8-0.60.20.5
Fe content in liver0.10.10.3-0.30.30.20.10.60.4
K content in liver1.41.43.6-0.30.61.9-1.70.11.1
Mg content in liver1.61.64.5-1.2-0.61.2-2.1-1.40.1
Mn content in liver2.12.44.2-1.11.22.1-1.61.21.8
Na content in liver0.60.61.9-0.00.90.80.11.40.4
Rb content in liver1.21.54.2-0.6-1.5-0.8-0.5-2.1-1.1
Se content in liver1.11.34.3-2.1-0.70.6-1.6-0.60.2
Sr content in liver2.32.14.10.51.81.20.12.01.8
Zn content in liver0.70.81.80.20.81.3-0.80.71.1