Hub : Genes

Slc29a2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000020025 0.03 0.02 2.2e-03 0.01 0 0 0 4.9e-02 8.7e-02 8.0e-02 9.6e-02
2 BLA gene expression ENSRNOG00000020025 0.51 0.15 1.4e-15 0.25 0.29 0.28 0.26 8.0e-14 7.4e-16 4.2e-15 3.1e-14
3 Brain gene expression ENSRNOG00000020025 0.07 0.04 3.3e-07 0.07 0.06 0.07 0.06 4.3e-07 2.9e-06 7.4e-07 1.1e-06
4 IL gene expression ENSRNOG00000020025 0.32 0.16 1.1e-05 0.11 0.14 0.09 0.09 1.2e-03 3.4e-04 3.7e-03 2.9e-03
5 Liver gene expression ENSRNOG00000020025 0.33 0.11 0.0e+00 0.14 0.13 0.14 0.14 1.9e-15 1.2e-14 7.4e-15 7.2e-15
6 NAcc gene expression ENSRNOG00000020025 0.05 0.04 4.4e-03 0.04 0.02 0.02 0.03 1.0e-03 1.6e-02 6.5e-03 3.9e-03
7 OFC gene expression ENSRNOG00000020025 0.23 0.13 1.1e-04 0.09 0.15 0.07 0.1 4.2e-03 1.9e-04 7.7e-03 2.0e-03
8 PL gene expression ENSRNOG00000020025 0.5 0.15 0.0e+00 0.34 0.34 0.32 0.36 1.6e-26 3.2e-26 1.1e-24 2.8e-28

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail2.27.010.7-2.6-2.4-2.5-3.2-2.8-2.8-1.2-3.3
BMI without tail1.02.13.3-1.2-1.5-1.2-1.6-1.6-1.6-0.7-1.8
Body weight3.816.119.1-3.8-4.0-3.7-4.4-4.1-4.1-3.5-4.4
Epididymis fat weight3.17.27.92.42.82.32.72.82.82.82.7
Glucose2.23.45.61.82.01.71.71.71.72.41.7
Heart weight2.84.05.11.52.11.52.22.02.02.32.1
Left kidney weight0.82.22.91.41.31.41.51.71.71.01.7
Right kidney weight0.31.01.80.61.00.70.81.41.40.11.3
Tail length0.82.44.8-0.9-1.9-0.9-1.2-1.7-1.7-2.2-1.4
Length with tail2.69.412.6-2.8-3.3-2.8-3.0-3.1-3.1-3.5-2.9
Length without tail2.96.37.2-2.4-2.5-2.4-2.7-2.5-2.5-2.6-2.6
Liver weight, left0.10.10.20.40.00.40.40.30.30.10.3
Liver weight, right0.10.10.40.6-0.30.70.2-0.2-0.20.1-0.0
Parametrial fat weight2.85.56.92.12.42.12.22.52.52.62.3
Retroperitoneal fat weight5.919.520.14.44.54.34.54.44.44.54.4
Intraocular pressure1.41.93.21.11.41.11.21.81.80.61.8
Extensor digitorum longus weight8.333.236.3-5.7-5.9-5.7-6.0-5.7-5.7-5.5-5.9
Soleus weight4.613.519.04.43.24.33.93.33.33.13.6
Tibialis anterior weight11.740.446.0-6.5-6.5-6.4-6.5-6.0-6.0-6.8-6.2
Tibia length0.61.73.7-1.4-1.1-1.3-1.6-0.8-0.8-1.9-1.1
Number of licking bursts0.20.20.4-0.5-0.3-0.5-0.6-0.4-0.4-0.4-0.5
Food consumed during 24 hour testing period0.10.10.10.20.20.30.00.30.3-0.30.4
Times rat made contact with spout0.60.71.1-0.7-0.7-0.7-0.8-1.0-1.0-0.4-1.0
Mean time between licks in bursts0.71.01.8-0.4-1.2-0.5-0.8-1.4-1.4-0.9-1.2
Mean num. licks in bursts0.10.10.30.40.20.40.40.10.10.50.2
Std. dev. time between licks in bursts0.10.20.50.3-0.70.30.2-0.5-0.5-0.4-0.2
Water consumed over 24 hours0.70.81.1-0.7-0.9-0.7-1.0-1.0-1.0-0.8-1.0
Indifference point 0 sec0.10.20.30.30.50.30.30.50.50.50.3
Indifference point AUC3.64.25.0-2.2-2.0-2.2-2.2-1.8-1.8-2.1-2.0
Indifference point function ln k7.610.714.03.72.93.73.72.92.93.13.2
Indifference point function log k7.610.714.03.72.93.73.72.92.93.13.2
Delay discounting total patch changes 0 sec0.00.00.00.20.20.20.20.20.20.10.2
Delay discounting total patch changes 12 sec4.76.38.0-2.4-2.4-2.5-2.8-2.4-2.4-2.3-2.7
Delay discounting total patch changes 18 sec0.50.71.3-1.1-0.6-1.1-1.0-0.6-0.6-0.6-0.7
Delay discounting total patch changes 24 sec2.43.03.5-1.4-1.8-1.4-1.9-1.8-1.8-1.9-1.8
Delay discounting total patch changes 6 sec1.31.92.5-1.4-1.3-1.4-1.6-1.4-1.4-1.0-1.5
Delay discounting time to switch 0 sec1.52.33.7-1.7-1.2-1.7-1.9-1.4-1.4-0.8-1.7
Delay discounting water rate 0 sec4.26.78.62.72.32.82.92.62.61.72.9
Delay discounting water rate 12 sec7.511.216.04.02.74.04.02.92.92.63.5
Delay discounting water rate 18 sec3.04.07.02.71.62.62.31.51.51.61.8
Delay discounting water rate 24 sec4.15.67.82.71.92.82.82.22.21.72.5
Delay discounting water rate 6 sec2.84.17.12.61.52.72.51.51.51.42.0
Locomotor activity1.01.62.91.60.91.61.70.90.90.91.3
Locomotor testing distance1.42.34.22.01.02.12.00.90.91.21.4
Locomotor testing rearing1.42.23.31.61.31.61.81.11.11.61.4
Light reinforcement 10.10.30.40.60.40.60.60.40.40.40.5
Light reinforcement 21.62.23.11.21.71.11.31.81.81.11.6
Reaction time number correct0.40.61.0-0.8-0.7-0.8-0.6-0.7-0.7-1.0-0.6
Reaction time mean minus median2.73.55.6-2.3-1.5-2.4-2.2-1.4-1.4-1.8-1.6
Reaction time mean minus median AUC1.92.54.1-1.9-1.4-2.0-1.6-1.2-1.2-1.7-1.3
Reaction time num false alarms0.10.20.50.7-0.50.70.3-0.4-0.4-0.3-0.1
Reaction time num false alarms AUC0.40.61.3-0.0-1.1-0.1-0.4-1.0-1.0-0.9-0.7
Reaction time trials correct on left0.40.61.0-0.8-0.7-0.8-0.6-0.7-0.7-1.0-0.6
Reaction time trials on left0.50.71.3-0.9-0.8-0.9-0.7-0.8-0.8-1.1-0.7
Reaction time mean0.00.10.1-0.30.2-0.4-0.10.30.3-0.00.2
Reaction time mean AUC0.10.10.1-0.20.3-0.3-0.00.40.40.10.3
Median of all reaction times0.20.20.40.10.60.10.40.60.60.50.5
Reaction time omissions1.82.43.1-1.7-1.5-1.8-1.6-1.4-1.4-1.6-1.3
Reaction time false alarm rate0.10.20.40.6-0.40.60.2-0.3-0.3-0.1-0.1
Reaction time premature initiation rate2.73.74.8-1.4-2.2-1.3-1.8-2.2-2.2-2.0-2.0
Reaction time premature initiations4.46.37.7-2.1-2.8-2.0-2.4-2.7-2.7-2.7-2.5
Std. dev. reaction times0.60.81.7-1.2-0.7-1.3-1.1-0.5-0.5-0.9-0.6
Reaction time trials completed0.50.71.3-0.9-0.8-0.9-0.7-0.8-0.8-1.1-0.7
Reaction time trials AUC0.30.50.8-0.7-0.7-0.7-0.5-0.7-0.7-0.9-0.5
Social response proportion0.50.51.0-0.7-0.5-0.6-1.0-0.7-0.7-0.5-0.8
Social responses0.20.30.4-0.3-0.6-0.3-0.6-0.6-0.6-0.6-0.6
Social time0.40.50.8-0.5-0.8-0.4-0.7-0.9-0.9-0.7-0.8
Conditioned locomotion2.32.83.6-1.5-1.9-1.5-1.5-1.7-1.7-1.8-1.6
Cocaine response after cond. corrected0.80.91.51.10.81.11.20.70.71.01.0
Cocaine response after cond. not corrected0.80.81.21.00.81.01.10.70.71.10.9
Cocaine response before conditioning0.30.40.7-0.8-0.3-0.8-0.8-0.3-0.3-0.5-0.6
Saline control response3.95.26.7-2.0-2.3-2.0-2.5-2.4-2.4-2.0-2.6
Condit. Reinf. active minus inactive responses0.50.61.30.61.10.60.40.90.90.90.6
Condit. Reinf. active-inactive response ratio1.61.62.61.01.61.01.01.51.51.21.2
Condit. Reinf. active responses0.10.10.4-0.10.6-0.1-0.20.10.10.6-0.1
Condit. Reinf. inactive responses0.50.60.9-0.8-0.6-0.8-0.9-0.9-0.9-0.0-1.0
Condit. Reinf. lever presses1.82.43.7-1.9-1.1-1.9-1.9-1.2-1.2-1.3-1.6
Condit. Reinf. lever reinforcers received0.10.10.3-0.40.3-0.5-0.6-0.1-0.10.2-0.4
Pavlov. Cond. lever latency0.30.40.80.80.40.80.90.30.30.60.6
Pavlov. Cond. magazine entry latency3.74.25.6-2.2-1.7-2.2-2.4-2.0-2.0-1.6-2.3
Pavlov. Cond. change in total contacts1.01.42.9-1.6-0.6-1.6-1.7-0.7-0.7-1.0-1.2
Pavlov. Cond. index score1.82.33.8-1.7-1.2-1.7-1.9-1.3-1.3-1.3-1.6
Pavlov. Cond. latency score1.51.93.1-1.5-1.0-1.5-1.8-1.1-1.1-1.2-1.5
Pavlov. Cond. lever contacts0.30.40.7-0.7-0.4-0.7-0.8-0.3-0.3-0.8-0.5
Pavlov. Cond. magazine entry number5.97.39.72.92.23.03.12.52.52.22.9
Pavlov. Cond. intertrial magazine entries1.31.72.11.21.31.21.51.41.41.21.5
Pavlov. Cond. lever-magazine prob. diff.2.33.04.6-1.9-1.4-1.9-2.1-1.5-1.5-1.5-1.8
Pavlov. Cond. response bias1.31.82.8-1.6-1.0-1.6-1.7-1.1-1.1-1.3-1.4
Conditioned reinforcement - actives0.30.30.50.60.60.60.50.70.60.30.7
Conditioned reinforcement - inactives6.57.49.32.33.02.32.92.92.82.53.0
Conditioned locomotion8.910.712.33.43.13.43.53.23.22.73.5
Intermittent access intake day 1-15 change0.60.61.00.40.80.40.81.01.00.21.0
Intermittent access intake escalation0.50.50.80.40.80.40.70.90.90.40.9
Intermittent access intake escalation 20.20.20.50.20.50.20.50.60.7-0.10.7
Intermitt. access day 1 inactive lever presses2.83.14.21.32.01.31.72.01.91.62.0
Intermitt. access day 15 inactive lever presses2.52.83.81.42.01.41.61.81.71.51.8
Intermitt. access escalation Index3.83.44.52.11.62.11.91.71.62.11.5
Intermittent access day 1 total infusions5.46.111.12.12.92.12.42.32.23.32.3
Intermittent access day 15 total infusions8.08.911.42.53.42.53.03.13.03.23.1
Intermittent access terminal intake (last 3 days)5.86.38.71.82.91.82.52.72.62.82.7
Intermittent access total infusions4.44.97.71.72.61.72.12.22.12.82.1
Intermittent access day 1 locomotion3.13.26.91.62.11.61.71.51.42.61.6
Intermittent access day 15 total locomotion5.15.47.12.02.72.02.32.42.32.52.3
Intermittent access total locomotion6.77.511.62.43.22.42.62.62.53.42.5
Intermittent access standard deviation0.90.91.40.51.10.51.21.01.10.81.2
Cocaine induced anxiety0.00.00.1-0.30.0-0.30.00.10.1-0.20.1
Post-drug Anxiety1.21.32.3-1.4-1.1-1.4-1.2-0.7-0.7-1.5-0.8
Baseline Anxiety2.32.43.5-1.4-1.7-1.4-1.7-1.4-1.4-1.9-1.5
Lifetime Intake3.64.17.01.62.41.61.92.01.82.61.9
Incentive Sensitization - Responses0.40.40.90.31.00.30.50.70.60.80.6
Incentive Sensitization - Breakpoint0.60.61.30.51.10.50.70.90.80.90.8
Progressive ratio test 1 active lever presses2.72.83.31.41.81.41.71.71.61.81.7
Progressive ratio test 1 breakpoint2.32.42.91.21.71.21.61.61.51.61.7
Progressive ratio test 1 inactive lever presses0.91.01.70.91.20.91.10.80.61.31.0
Progressive ratio test 2 active lever presses4.14.46.01.72.51.72.12.22.12.32.2
Progressive ratio test 2 breakpoint5.05.67.02.02.62.02.52.42.32.42.5
Progressive ratio test 2 inactive lever presses8.910.313.02.83.62.83.33.23.13.53.2
Total sessions with >9 infusions1.41.52.61.11.31.11.21.11.01.61.1
Short access day 1 total inactive lever presses4.24.65.81.82.21.92.22.42.22.32.1
Short access day 10 total inactive lever presses2.73.04.11.51.71.52.01.81.71.72.0
Short access day 1 total infusions3.33.56.01.72.01.71.71.91.72.51.7
Short access day 10 total infusions1.11.24.30.51.50.50.80.80.72.10.7
Short access total infusions1.11.23.10.91.30.91.01.00.81.80.9
Short access day 1 locomotion2.02.14.41.41.71.41.31.21.12.11.2
Short access day 10 total locomotion1.21.33.41.11.41.11.10.80.61.80.8
Short access total locomotion1.01.12.90.91.30.90.90.70.61.70.8
Compulsive drug intake3.53.55.5-1.0-2.4-1.0-1.8-2.1-2.2-2.0-2.0
One hour access (0.3 mA shock)9.811.413.13.33.63.33.53.23.03.43.5
One hour access (shock baseline)9.611.215.32.63.92.63.43.53.43.43.6
Number of responses in last shaping day0.90.91.30.90.80.91.11.01.00.91.1
Context. condit. distance diff. score2.02.42.91.71.41.71.71.41.41.51.5
Locomotion velocity, session 10.10.10.10.2-0.40.20.1-0.4-0.4-0.3-0.2
Locomotion distance, session 10.50.71.5-0.4-0.7-0.3-0.9-1.1-1.1-0.1-1.2
Locomotion velocity, session 23.03.54.3-1.8-1.9-1.8-2.0-1.9-1.9-1.6-2.1
Locomotion distance, session 21.01.42.3-0.7-1.2-0.6-1.2-1.5-1.5-0.6-1.5
Locomotion velocity, session 30.10.10.30.30.20.40.20.10.10.50.0
Locomotion distance, session 30.00.00.00.10.10.20.10.10.10.10.1
Stereotopy head waving bouts, day 30.50.61.30.90.61.00.80.50.51.10.6
Stereotopy head waving duration, day 31.01.31.91.11.11.21.11.01.01.41.0
Locomotion velocity, session 70.20.20.70.50.40.30.30.30.30.90.3
Locomotion distance, session 70.10.10.20.0-0.5-0.1-0.1-0.5-0.50.1-0.4
Stereotopy head waving bouts, day 70.60.61.10.21.00.30.41.11.10.90.8
Stereotopy head waving duration, day 70.50.61.7-1.3-0.3-1.2-1.1-0.3-0.3-0.3-0.7
Locomotion velocity, session 81.11.41.9-0.7-1.4-0.5-1.1-1.4-1.4-1.3-1.3
Locomotion distance, session 80.30.41.11.00.41.10.50.30.30.70.3
Degree of sensitization distance0.10.10.2-0.1-0.3-0.2-0.2-0.4-0.40.2-0.4
Degree of sensitization stereotypy0.30.31.1-1.00.0-1.0-0.70.10.1-0.2-0.2
Condit. Reinf. active minus inactive responses0.20.20.3-0.5-0.2-0.5-0.5-0.5-0.5-0.2-0.6
Condit. Reinf. active-inactive response ratio0.00.00.0-0.00.2-0.1-0.1-0.1-0.10.1-0.1
Condit. Reinf. active responses0.10.10.3-0.5-0.2-0.5-0.4-0.3-0.3-0.2-0.4
Condit. Reinf. inactive responses0.00.00.1-0.3-0.0-0.2-0.00.10.10.10.0
Incentive salience index mean0.30.40.6-0.5-0.5-0.5-0.7-0.7-0.7-0.3-0.8
Condit. Reinf. lever presses0.20.30.5-0.5-0.5-0.4-0.7-0.5-0.5-0.6-0.6
Time in familiar zone, hab. session 10.40.40.50.70.70.70.40.50.50.70.4
Time in novel zone, hab. session 10.00.00.20.1-0.10.10.5-0.0-0.0-0.00.2
Total zone transitions, hab. session 10.91.21.6-1.0-1.1-1.0-1.2-1.2-1.2-0.9-1.3
Total locomotion distance, hab. session 10.20.30.50.60.60.50.70.50.50.70.5
Locomotion velocity, hab. session 10.00.00.10.10.10.10.10.00.00.30.0
Time in familiar zone, hab. session 20.20.20.4-0.2-0.6-0.0-0.1-0.6-0.6-0.4-0.3
Time in novel zone, hab. session 20.00.00.1-0.10.3-0.2-0.20.20.20.3-0.0
Total zone transitions, hab. session 21.21.52.8-1.1-0.8-1.1-1.5-1.4-1.4-0.1-1.7
Total locomotion distance, hab. session 20.10.10.70.20.20.20.0-0.1-0.10.8-0.2
Locomotion velocity, hab. session 20.20.21.00.50.50.50.20.20.21.00.0
Novel to familiar place preference ratio0.50.51.2-1.1-0.2-1.1-1.0-0.2-0.2-0.5-0.5
Novelty place preference0.20.20.4-0.60.2-0.7-0.60.20.2-0.1-0.2
Time in novel zone, NPP test0.10.10.4-0.60.2-0.6-0.50.20.2-0.0-0.1
Total zone transitions, NPP test1.82.53.9-1.3-1.5-1.2-1.8-1.8-1.8-1.2-2.0
Total locomotion distance, NPP test0.10.10.20.1-0.20.2-0.2-0.4-0.40.1-0.4
Locomotion velocity, NPP test0.10.10.20.2-0.20.2-0.3-0.4-0.40.0-0.5
Pavlov. Cond. lever latency0.10.20.30.50.40.40.50.30.30.30.5
Pavlov. Cond. magazine entry latency0.00.10.2-0.20.3-0.2-0.30.10.10.4-0.2
Pavlov. Cond. change in total contacts0.20.20.40.00.60.1-0.00.60.60.30.3
Pavlov. Cond. index score0.00.00.0-0.20.1-0.1-0.20.10.1-0.1-0.1
Pavlov. Cond. latency score0.00.00.0-0.10.1-0.0-0.10.10.10.1-0.0
Pavlov. Cond. lever contacts0.00.00.0-0.1-0.0-0.0-0.1-0.0-0.0-0.0-0.1
Pavlov. Cond. magazine entry number0.10.10.30.5-0.10.50.3-0.1-0.10.30.1
Pavlov. Cond. intertrial magazine entries0.20.30.40.20.50.20.60.70.70.20.7
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.4-0.1-0.3-0.5-0.1-0.1-0.3-0.3
Pavlov. Cond. response bias0.00.00.1-0.30.1-0.2-0.20.10.1-0.2-0.0
Bone: apparent density0.30.61.1-1.0-0.1-1.0-0.9-0.5-0.50.3-0.9
Bone surface3.05.38.5-2.9-1.5-2.9-2.8-1.9-1.9-1.4-2.4
Bone volume0.91.53.0-1.7-0.5-1.7-1.6-0.8-0.8-0.4-1.3
Bone: connectivity density1.82.94.4-2.0-1.2-2.0-2.1-1.6-1.6-0.7-2.0
Bone: cortical apparent density0.30.40.6-0.4-0.8-0.4-0.6-0.7-0.7-0.7-0.6
Bone: cortical area0.71.11.8-1.2-1.0-1.2-1.1-0.8-0.8-1.3-0.9
Bone: cortical porosity0.10.10.2-0.0-0.20.0-0.3-0.4-0.40.2-0.4
Bone: cortical porosity0.50.50.8-0.6-0.7-0.6-0.8-0.9-0.9-0.4-0.9
Bone: cortical thickness4.37.09.9-2.6-2.9-2.6-2.5-2.5-2.5-3.1-2.4
Bone: cortical thickness1.61.83.1-0.9-1.8-0.9-1.1-1.5-1.5-1.7-1.2
Bone: cortical tissue density0.40.50.8-0.5-0.9-0.5-0.7-0.8-0.8-0.8-0.7
Bone: elastic displacement0.40.51.21.10.11.10.90.20.20.00.6
Bone: elastic work1.52.03.3-0.7-1.8-0.8-1.1-1.6-1.6-1.7-1.4
Bone: endosteal estimation1.22.64.41.51.81.51.41.61.62.11.4
Bone: endosteal perimeter2.14.36.51.92.51.91.62.12.12.51.7
Bone: final force2.54.14.9-2.1-1.9-2.1-2.2-1.9-1.9-1.9-2.1
Bone: final moment2.13.54.3-1.9-1.8-1.9-2.1-1.8-1.8-1.8-2.0
Bone: marrow area1.32.74.61.51.81.51.51.61.62.21.4
Bone: maximum diameter0.00.00.1-0.20.2-0.2-0.30.20.2-0.30.0
Bone: maximum force2.54.36.4-2.3-1.7-2.3-2.5-1.9-1.9-1.6-2.3
Bone: maximum moment2.13.75.5-2.0-1.6-2.0-2.3-1.8-1.8-1.4-2.2
Bone: minimum diameter0.91.73.81.01.61.01.01.31.31.91.1
Bone: periosteal estimation0.10.10.20.00.40.00.10.50.50.30.3
Bone: periosteal perimeter0.00.00.1-0.20.3-0.1-0.30.10.10.2-0.1
Bone: post-yield work0.30.51.7-0.41.0-0.4-0.70.40.41.3-0.3
Bone: stiffness1.82.94.9-2.2-1.1-2.2-2.1-1.3-1.3-1.1-1.8
Bone: tissue strength0.00.00.1-0.10.3-0.1-0.10.10.10.2-0.0
Bone: trabecular number0.40.71.5-1.2-0.1-1.2-1.1-0.4-0.40.1-0.8
Bone: trabecular spacing0.30.31.01.00.11.00.60.10.10.20.4
Bone: trabecular thickness0.40.51.50.51.00.50.50.70.71.20.5
Bone: trabecular tissue density4.05.76.62.42.32.42.62.42.41.92.6
Breakpoint value in progressive ratio session3.03.44.5-2.0-1.7-1.9-2.1-1.6-1.6-1.9-1.8
Distance traveled before self-admin0.30.30.6-0.8-0.4-0.7-0.6-0.4-0.3-0.5-0.4
Distance traveled after self-admin0.10.10.5-0.7-0.1-0.6-0.4-0.2-0.1-0.3-0.1
Delta time in closed arm before/after self-admin0.90.91.4-1.0-1.0-1.0-0.4-1.2-1.2-0.6-0.7
Delta time in open arm before/after self-admin0.20.20.7-0.30.3-0.3-0.00.80.8-0.10.5
Diff in mean of infusions in LGA sessions0.50.51.1-0.9-0.6-1.1-0.7-0.4-0.4-0.9-0.4
Extinction: sum of active levers before priming3.73.85.9-1.8-1.9-1.7-2.4-1.8-1.9-1.8-2.1
Active lever presses in extinction session 62.72.64.3-2.0-1.3-2.1-1.5-1.3-1.3-1.9-1.2
Delta distance traveled before/after self-admin0.00.00.00.20.00.10.10.00.1-0.00.1
Delta ambulatory time before/after self-admin0.00.00.10.1-0.20.0-0.0-0.3-0.3-0.1-0.1
Time in closed arm before self-admin0.10.10.30.10.40.20.00.50.60.30.3
Time in closed arm after self-admin0.10.10.3-0.6-0.2-0.5-0.0-0.3-0.30.0-0.1
Time in open arm before self-admin0.20.20.50.7-0.20.60.5-0.3-0.40.4-0.0
Time in open arm after self-admin0.20.20.40.30.20.20.50.70.60.10.6
Sum of active levers in priming session hrs 5-61.01.03.1-1.1-0.7-1.1-1.1-0.5-0.5-1.8-0.6
Time to tail flick, vehicle, before self-admin0.60.71.1-1.0-0.5-1.0-0.8-0.9-0.8-0.3-0.9
Time to tail flick, vehicle, after self-admin2.02.22.7-1.5-1.5-1.6-1.4-1.6-1.6-0.9-1.6
Time to tail flick, test, before self-admin0.30.31.30.60.40.60.60.0-0.01.10.2
Time to tail flick, test, after self-admin0.00.00.2-0.4-0.0-0.2-0.0-0.1-0.1-0.1-0.2
Delta time to tail flick, vehicle, before/after SA0.60.60.8-0.8-0.8-0.7-0.8-0.8-0.9-0.5-0.8
Delta time to tail flick, test, before/after SA1.21.02.6-1.3-0.9-1.1-0.9-0.7-0.6-1.6-0.7
Ambulatory time before self-admin0.20.20.6-0.80.0-0.6-0.50.10.1-0.3-0.2
Ambulatory time after self-admin0.30.40.9-0.10.9-0.10.30.70.80.70.6
Total heroin consumption4.35.17.5-2.0-2.4-1.9-2.7-2.1-2.0-2.5-2.4
Area under the delay curve0.30.30.91.00.31.00.2-0.1-0.10.8-0.0
Delay disc. indifference point, 0s delay0.70.71.91.40.41.40.8-0.2-0.21.10.2
Delay disc. indifference point, 16s delay1.41.42.11.21.51.21.01.01.01.41.1
Delay disc. indifference point, 2s delay0.20.20.50.70.40.70.40.30.30.60.3
Delay disc. indifference point, 24s delay0.10.10.10.4-0.20.30.2-0.3-0.30.0-0.0
Delay disc. indifference point, 4s delay0.30.41.11.00.11.10.4-0.2-0.20.70.0
Delay disc. indifference point, 8s delay0.20.30.70.8-0.10.80.2-0.4-0.40.5-0.2
Delay discount exponential model param0.20.20.7-0.9-0.2-0.8-0.20.20.2-0.60.1
Delay discount hyperbolic model param0.20.20.7-0.8-0.1-0.8-0.10.30.3-0.50.1
Fecal boli incidents, locomotor time 10.20.20.4-0.40.5-0.4-0.10.60.6-0.10.4
Change in fecal boli incidents, locomotor task0.30.31.0-0.0-0.4-0.0-0.1-1.0-1.00.1-0.6
Time >=10cm from walls, locomotor time 11.21.22.60.61.60.60.81.01.11.60.8
Bouts of movement, locomotor time 11.01.11.5-1.2-0.8-1.2-1.2-0.9-0.9-1.1-1.0
Total resting periods, locomotor time 10.50.61.0-0.9-0.5-0.9-1.0-0.5-0.6-0.8-0.7
Rest time, locomotor task time 11.71.92.21.51.41.41.51.31.31.01.5
Distance moved, locomotor task time 10.30.30.6-0.5-0.4-0.5-0.5-0.7-0.70.0-0.7
Vertical activity count, locomotor time 10.80.81.21.00.91.01.10.70.60.91.0
Time >=10cm from walls, locomotor time 20.10.10.20.30.40.20.10.50.40.20.2
Bouts of movement, locomotor time 20.60.60.8-0.9-0.7-0.8-0.9-0.8-0.8-0.7-0.8
Total resting periods, locomotor time 20.30.30.4-0.7-0.4-0.6-0.6-0.5-0.5-0.4-0.5
Rest time, locomotor task time 22.52.93.41.91.61.81.91.61.61.71.7
Distance moved, locomotor task time 21.41.62.2-1.2-1.2-1.1-1.2-1.4-1.5-1.2-1.3
Vertical activity count, locomotor time 20.20.30.6-0.1-0.7-0.1-0.0-0.7-0.8-0.8-0.2
Weight adjusted by age3.13.54.0-2.0-1.7-2.0-1.9-1.8-1.8-1.9-1.9
Seeking ratio, delayed vs. immediate footshock0.10.10.20.50.10.3-0.0-0.3-0.40.5-0.3
Locomotion in novel chamber5.56.87.92.62.82.72.72.52.52.42.7
Locomotion in novel chamber post-restriction2.93.44.71.51.91.62.11.81.91.82.2
Progressive ratio1.61.82.7-1.5-1.0-1.6-1.7-1.2-1.2-0.5-1.6
Food seeking constrained by brief footshock0.50.61.1-0.4-0.9-0.5-0.6-1.0-1.0-0.7-0.9
Seeking ratio, punishment vs. effort1.01.22.71.70.61.61.40.60.60.51.1
Run reversals in cocaine runway, females1.01.01.9-0.8-1.0-0.8-0.9-1.3-1.3-0.2-1.4
Run reversals in cocaine runway, males0.10.10.3-0.4-0.2-0.20.50.20.2-0.50.4
Latency to leave start box in cocaine runway0.10.10.30.00.4-0.1-0.00.20.20.50.2
Latency to leave start box in cocaine runway, F0.00.00.1-0.00.1-0.0-0.1-0.2-0.00.30.0
Latency to leave start box in cocaine runway, M0.00.00.1-0.10.1-0.4-0.10.10.10.00.1
Cd content in liver1.61.72.50.91.40.81.51.61.61.01.5
Co content in liver0.70.81.81.30.31.31.30.60.60.50.9
Cu content in liver0.30.30.5-0.5-0.6-0.5-0.7-0.5-0.5-0.5-0.6
Fe content in liver0.10.10.3-0.4-0.3-0.3-0.4-0.2-0.2-0.5-0.4
K content in liver1.51.52.4-1.1-1.1-1.0-1.5-1.3-1.3-0.8-1.5
Mg content in liver0.10.10.4-0.10.1-0.0-0.5-0.3-0.30.6-0.5
Mn content in liver2.22.63.7-1.9-1.3-1.8-1.9-1.3-1.3-1.6-1.6
Na content in liver0.60.61.5-0.4-0.8-0.4-0.9-0.7-0.7-1.2-0.9
Rb content in liver1.21.63.31.01.31.01.31.11.11.81.0
Se content in liver0.10.20.4-0.20.7-0.2-0.10.50.50.40.4
Sr content in liver2.82.53.8-1.8-1.6-1.8-1.6-1.3-1.3-2.0-1.3
Zn content in liver1.21.31.7-1.1-1.1-1.1-1.3-1.2-1.2-1.0-1.1