Hub : Genes

Map2k2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability ENSRNOG00000020005 0.05 0.04 7.1e-06 0.04 0.04 0.03 0.03 2.4e-05 5.6e-05 5.7e-04 2.1e-04
2 BLA alternative polyA ENSRNOT00000102006 0.08 0.05 3.5e-05 0.09 0.08 0.08 0.08 2.7e-05 4.7e-05 5.1e-05 4.5e-05
3 BLA alternative polyA ENSRNOT00000107951 0.07 0.05 1.3e-04 0.04 0.06 0.05 0.05 3.4e-03 5.7e-04 1.4e-03 1.8e-03
4 BLA gene expression ENSRNOG00000020005 0.17 0.11 3.8e-11 0.19 0.22 0.22 0.21 1.9e-10 3.6e-12 5.8e-12 1.4e-11
5 BLA mRNA stability ENSRNOG00000020005 0.41 0.16 0.0e+00 0.46 0.46 0.46 0.46 5.6e-27 4.5e-27 5.7e-27 2.4e-27
6 Brain alternative polyA ENSRNOT00000102006 0.06 0.04 2.0e-05 0.05 0.05 0.04 0.05 9.1e-06 1.7e-05 7.2e-05 1.2e-05
7 Brain alternative polyA ENSRNOT00000107951 0.08 0.06 3.4e-07 0.07 0.07 0.05 0.07 2.6e-07 5.2e-07 8.8e-06 1.8e-07
8 Brain gene expression ENSRNOG00000020005 0.09 0.06 8.2e-08 0.07 0.08 0.07 0.07 5.7e-07 1.4e-07 8.1e-07 3.6e-07
9 Brain mRNA stability ENSRNOG00000020005 0.44 0.15 0.0e+00 0.47 0.46 0.46 0.47 3.1e-48 7.3e-47 1.6e-47 7.3e-48
10 Eye alternative polyA ENSRNOT00000107951 0.56 0.22 5.3e-04 0.18 0.14 0.07 0.16 1.1e-03 4.1e-03 3.1e-02 1.9e-03
11 Eye gene expression ENSRNOG00000020005 0.98 0.01 1.3e-03 -0.02 0.05 0.05 0.07 6.6e-01 5.9e-02 5.9e-02 3.6e-02
12 Eye mRNA stability ENSRNOG00000020005 0.37 0.18 3.6e-05 0.27 0.21 0.22 0.24 5.4e-05 3.9e-04 2.9e-04 1.4e-04
13 IL mRNA stability ENSRNOG00000020005 0.29 0.17 8.3e-05 0.07 0.09 0.08 0.07 9.9e-03 4.4e-03 4.8e-03 8.4e-03
14 LHb mRNA stability ENSRNOG00000020005 0.36 0.17 3.1e-09 0.35 0.32 0.33 0.3 4.2e-09 2.4e-08 1.5e-08 6.3e-08
15 Liver alternative polyA ENSRNOT00000027272 0.02 0.02 3.7e-03 0.01 0.01 0 0.01 6.1e-02 5.6e-02 1.6e-01 6.9e-02
16 Liver alternative polyA ENSRNOT00000107951 0.02 0.02 7.9e-03 0.01 0.01 0 0 4.3e-02 3.4e-02 7.5e-02 1.0e-01
17 Liver mRNA stability ENSRNOG00000020005 0.03 0.03 1.1e-03 0.03 0.02 0.02 0.02 5.0e-04 1.4e-03 4.1e-03 9.1e-04
18 NAcc gene expression ENSRNOG00000020005 0.05 0.04 1.7e-04 0.03 0.04 0.02 0.03 3.7e-03 1.1e-03 6.2e-03 2.3e-03
19 NAcc mRNA stability ENSRNOG00000020005 0.44 0.18 0.0e+00 0.47 0.47 0.47 0.47 1.1e-38 7.5e-39 3.6e-39 1.1e-38
20 OFC gene expression ENSRNOG00000020005 0.24 0.15 3.6e-05 0.18 0.15 0.18 0.16 5.1e-05 1.8e-04 4.1e-05 1.0e-04
21 OFC mRNA stability ENSRNOG00000020005 0.33 0.16 1.8e-08 0.33 0.31 0.32 0.32 1.1e-08 3.7e-08 1.7e-08 2.5e-08
22 PL gene expression ENSRNOG00000020005 0.18 0.1 0.0e+00 0.23 0.22 0.22 0.22 1.1e-17 2.5e-16 1.3e-16 9.3e-17
23 PL mRNA stability ENSRNOG00000020005 0.45 0.18 0.0e+00 0.44 0.48 0.48 0.48 1.0e-36 9.2e-41 1.9e-40 3.0e-41

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
BMI with tail6.220.022.8-4.6-4.64.7-4.6-4.7-4.64.5-3.8-4.64.60.2-4.5-4.8-4.5-4.84.8-4.6-4.8-4.7-3.8-4.6-4.6-4.7
BMI without tail1.94.15.6-2.0-2.02.1-2.0-2.1-2.02.0-1.3-2.02.40.6-2.0-2.3-2.0-2.32.3-2.4-2.3-2.1-1.3-2.0-2.0-2.2
Body weight1.14.75.6-2.2-2.22.2-2.2-2.3-2.22.2-1.8-2.22.40.4-2.1-2.3-2.2-2.32.3-2.4-2.3-2.3-1.8-2.2-2.2-2.3
Epididymis fat weight0.20.50.90.80.8-0.70.70.80.8-0.81.00.8-0.30.70.80.60.70.5-0.50.30.50.70.90.70.80.6
Glucose1.11.72.1-1.3-1.31.4-1.4-1.3-1.31.2-1.1-1.41.30.2-1.4-1.4-1.3-1.41.4-1.3-1.4-1.4-1.1-1.3-1.3-1.3
Heart weight0.40.61.10.80.8-0.80.80.90.9-0.91.00.8-0.40.70.80.60.80.6-0.60.40.60.71.10.90.90.7
Left kidney weight0.10.21.80.00.0-0.20.10.20.0-0.0-0.30.0-0.8-1.30.00.30.10.4-0.40.80.40.2-0.20.10.00.3
Right kidney weight1.43.95.02.02.0-2.02.02.11.9-2.01.61.9-2.2-0.62.02.12.02.1-2.12.22.12.11.71.91.92.1
Tail length3.29.711.13.33.3-3.33.33.33.3-3.33.13.3-2.60.83.23.23.33.1-3.12.63.13.33.23.33.33.2
Length with tail1.86.47.82.62.6-2.72.62.72.6-2.62.12.5-2.50.02.62.82.52.8-2.82.52.82.72.12.62.62.7
Length without tail0.10.10.8-0.0-0.0-0.20.10.10.00.0-0.5-0.0-0.6-0.90.00.4-0.00.4-0.40.60.50.2-0.5-0.00.00.3
Liver weight, left2.33.74.7-1.9-1.92.0-1.9-2.0-1.81.8-1.4-1.92.10.5-1.9-2.1-2.0-2.22.2-2.1-2.2-2.0-1.5-1.9-1.8-2.0
Liver weight, right1.72.83.2-1.8-1.81.8-1.8-1.8-1.71.7-1.6-1.81.5-0.2-1.8-1.8-1.8-1.81.8-1.5-1.8-1.8-1.6-1.8-1.7-1.7
Parametrial fat weight0.51.01.21.01.0-1.01.01.01.1-1.01.01.0-0.70.51.11.01.01.0-1.00.71.01.01.01.11.11.0
Retroperitoneal fat weight0.41.32.7-1.0-1.01.1-1.0-1.2-1.11.1-0.7-0.91.61.0-0.9-1.2-1.0-1.21.2-1.6-1.2-1.1-0.8-1.0-1.1-1.3
Intraocular pressure0.20.31.80.40.4-0.30.40.30.5-0.51.00.50.41.30.50.10.5-0.0-0.0-0.4-0.10.31.00.50.50.1
Extensor digitorum longus weight4.016.222.2-3.9-3.94.2-4.0-4.2-3.93.9-2.9-3.94.71.7-4.1-4.4-3.9-4.54.5-4.7-4.5-4.2-3.0-3.9-3.9-4.4
Soleus weight8.725.528.4-5.2-5.25.3-5.2-5.3-5.25.1-4.5-5.24.90.3-5.2-5.3-5.2-5.35.3-4.9-5.3-5.3-4.6-5.2-5.2-5.3
Tibialis anterior weight1.03.44.4-1.9-1.92.0-2.0-1.9-1.81.8-1.7-2.01.7-0.0-2.1-2.0-1.9-2.02.0-1.7-2.0-2.0-1.7-1.9-1.8-1.9
Tibia length0.92.63.11.71.7-1.71.71.81.8-1.81.61.7-1.40.41.71.71.71.6-1.61.41.61.71.61.71.81.7
Number of licking bursts0.20.21.90.20.2-0.00.1-0.10.00.00.60.20.81.40.2-0.20.2-0.30.2-0.8-0.3-0.00.60.20.0-0.3
Food consumed during 24 hour testing period0.40.50.6-0.7-0.70.8-0.7-0.8-0.80.8-0.6-0.70.70.1-0.7-0.8-0.7-0.80.8-0.7-0.8-0.8-0.6-0.7-0.8-0.8
Times rat made contact with spout0.20.20.7-0.3-0.30.4-0.3-0.3-0.30.20.1-0.30.70.9-0.3-0.5-0.3-0.50.5-0.7-0.5-0.40.0-0.3-0.3-0.5
Mean time between licks in bursts4.25.86.62.62.6-2.52.62.52.5-2.52.52.6-1.90.72.62.42.62.4-2.41.92.42.52.52.62.52.4
Mean num. licks in bursts0.10.10.3-0.3-0.30.2-0.3-0.0-0.20.1-0.4-0.3-0.3-0.5-0.3-0.1-0.3-0.10.10.3-0.1-0.2-0.4-0.3-0.20.0
Std. dev. time between licks in bursts0.70.81.80.80.8-0.90.80.90.7-0.70.30.8-1.3-1.10.81.10.81.1-1.11.31.10.90.30.80.71.0
Water consumed over 24 hours0.70.81.6-1.0-1.00.9-1.0-0.9-1.01.0-1.3-1.00.3-1.1-1.0-0.7-1.0-0.70.7-0.3-0.7-0.9-1.2-1.0-1.0-0.7
Indifference point 0 sec0.20.30.4-0.5-0.50.5-0.5-0.6-0.60.5-0.6-0.50.4-0.1-0.5-0.5-0.5-0.50.5-0.4-0.4-0.5-0.6-0.6-0.6-0.6
Indifference point AUC1.11.31.51.21.2-1.11.21.21.2-1.21.11.2-1.0-0.01.11.11.21.1-1.11.01.11.21.21.21.21.2
Indifference point function ln k0.20.30.5-0.6-0.60.6-0.6-0.6-0.60.6-0.5-0.60.70.3-0.6-0.6-0.6-0.60.6-0.7-0.6-0.6-0.6-0.6-0.6-0.6
Indifference point function log k0.20.30.5-0.6-0.60.6-0.6-0.6-0.60.6-0.5-0.60.70.3-0.6-0.6-0.6-0.60.6-0.7-0.6-0.6-0.6-0.6-0.6-0.6
Delay discounting total patch changes 0 sec0.10.20.3-0.4-0.40.4-0.4-0.5-0.50.5-0.4-0.40.40.1-0.4-0.4-0.4-0.40.4-0.4-0.4-0.4-0.5-0.5-0.5-0.5
Delay discounting total patch changes 12 sec0.20.30.7-0.4-0.40.5-0.4-0.5-0.50.30.0-0.40.80.7-0.3-0.7-0.4-0.70.7-0.8-0.7-0.5-0.0-0.4-0.5-0.6
Delay discounting total patch changes 18 sec1.01.31.51.21.2-1.21.21.21.2-1.11.11.2-1.10.01.21.21.21.2-1.21.11.21.21.21.21.21.2
Delay discounting total patch changes 24 sec0.10.10.20.30.3-0.30.30.30.2-0.30.20.3-0.5-0.40.30.30.30.3-0.30.50.30.30.30.30.20.3
Delay discounting total patch changes 6 sec0.20.20.30.60.6-0.50.50.50.4-0.50.40.6-0.40.20.60.50.60.5-0.50.40.50.50.40.40.40.4
Delay discounting time to switch 0 sec1.82.84.2-1.8-1.81.7-1.8-1.7-1.91.8-2.0-1.81.0-1.0-1.7-1.5-1.8-1.51.5-1.0-1.4-1.7-2.0-1.8-1.9-1.6
Delay discounting water rate 0 sec0.20.31.90.60.5-0.40.50.40.5-0.51.00.60.41.40.50.20.50.1-0.1-0.40.10.41.00.50.50.1
Delay discounting water rate 12 sec0.81.13.3-0.8-0.81.0-0.8-1.1-0.80.9-0.1-0.81.81.4-0.8-1.2-0.8-1.31.3-1.8-1.3-1.0-0.1-0.8-0.8-1.3
Delay discounting water rate 18 sec0.71.06.01.00.9-0.60.80.70.8-0.91.81.00.82.40.90.20.90.1-0.1-0.80.00.61.70.80.80.2
Delay discounting water rate 24 sec0.70.99.20.10.10.2-0.0-0.20.1-0.11.10.11.93.00.0-0.60.1-0.80.7-1.9-0.8-0.31.00.10.1-0.7
Delay discounting water rate 6 sec0.71.03.41.11.1-0.91.00.91.1-1.11.61.10.21.81.00.71.10.6-0.6-0.20.50.81.51.11.10.6
Locomotor activity3.04.87.72.12.1-2.32.12.32.0-2.11.32.1-2.8-1.12.12.52.12.5-2.52.82.62.31.42.12.02.4
Locomotor testing distance1.93.14.51.71.7-1.81.81.81.7-1.71.21.7-2.1-0.71.82.01.72.0-2.02.12.01.91.21.71.71.9
Locomotor testing rearing0.00.10.20.30.3-0.30.30.30.3-0.30.40.3-0.10.30.30.20.30.2-0.20.10.20.30.40.30.30.2
Light reinforcement 15.39.711.33.13.1-3.33.23.33.1-3.22.73.1-3.2-0.23.13.33.23.3-3.33.23.43.22.73.23.13.3
Light reinforcement 21.72.22.71.51.5-1.61.51.61.5-1.51.21.5-1.50.11.51.61.61.6-1.61.51.61.61.21.51.51.5
Reaction time number correct0.40.61.9-0.5-0.50.7-0.6-0.7-0.60.60.0-0.51.41.2-0.5-0.9-0.5-0.90.9-1.4-1.0-0.7-0.0-0.6-0.6-0.9
Reaction time mean minus median0.81.11.41.11.0-1.11.01.11.0-1.00.81.1-1.2-0.51.01.11.01.1-1.11.21.11.10.91.01.01.1
Reaction time mean minus median AUC0.20.33.3-0.2-0.20.0-0.1-0.0-0.10.2-0.7-0.2-0.9-1.8-0.30.2-0.20.3-0.20.90.30.0-0.6-0.1-0.10.3
Reaction time num false alarms0.00.00.1-0.0-0.00.1-0.1-0.1-0.10.00.1-0.00.30.4-0.1-0.20.0-0.20.2-0.3-0.2-0.10.2-0.0-0.1-0.2
Reaction time num false alarms AUC0.10.10.5-0.1-0.10.2-0.1-0.2-0.10.10.3-0.10.60.7-0.1-0.30.0-0.40.4-0.6-0.4-0.20.3-0.1-0.1-0.3
Reaction time trials correct on left0.40.61.9-0.5-0.50.7-0.6-0.7-0.60.60.0-0.51.41.2-0.5-0.9-0.5-0.90.9-1.4-1.0-0.7-0.0-0.6-0.6-0.9
Reaction time trials on left0.40.61.8-0.5-0.60.7-0.6-0.7-0.60.6-0.0-0.51.31.1-0.5-0.9-0.6-0.90.9-1.3-1.0-0.7-0.1-0.6-0.6-0.9
Reaction time mean0.10.21.9-0.2-0.20.1-0.2-0.2-0.30.3-0.6-0.2-0.5-1.4-0.30.0-0.30.1-0.10.50.1-0.1-0.5-0.2-0.30.0
Reaction time mean AUC0.10.21.7-0.3-0.30.2-0.3-0.3-0.40.4-0.7-0.3-0.4-1.3-0.3-0.0-0.30.00.00.40.0-0.2-0.7-0.3-0.4-0.1
Median of all reaction times0.40.61.7-0.7-0.80.7-0.7-0.8-0.80.9-1.1-0.70.1-1.3-0.8-0.5-0.8-0.40.5-0.1-0.4-0.6-1.1-0.8-0.8-0.6
Reaction time omissions0.20.30.50.60.6-0.60.60.60.5-0.50.30.6-0.7-0.40.50.60.60.7-0.70.70.70.60.40.60.50.6
Reaction time false alarm rate0.00.00.1-0.1-0.00.1-0.1-0.0-0.10.0-0.1-0.1-0.1-0.2-0.1-0.10.0-0.00.10.1-0.0-0.0-0.0-0.0-0.1-0.0
Reaction time premature initiation rate1.11.52.31.41.4-1.31.31.31.3-1.31.51.4-0.61.21.41.11.31.1-1.10.61.11.31.51.31.31.1
Reaction time premature initiations0.81.23.61.21.2-1.01.11.01.1-1.11.61.20.11.91.20.81.10.7-0.7-0.10.61.01.61.11.10.6
Std. dev. reaction times0.30.41.00.50.5-0.60.50.50.5-0.40.20.5-0.9-1.00.40.60.50.7-0.70.90.70.60.30.50.50.7
Reaction time trials completed0.40.61.8-0.5-0.60.7-0.6-0.7-0.60.6-0.0-0.51.31.1-0.5-0.9-0.6-0.90.9-1.3-1.0-0.7-0.1-0.6-0.6-0.9
Reaction time trials AUC0.40.62.0-0.4-0.50.6-0.5-0.7-0.50.50.2-0.41.41.4-0.4-0.8-0.5-0.90.9-1.4-1.0-0.70.1-0.5-0.5-0.9
Social response proportion0.50.51.00.60.7-0.70.70.80.7-0.70.40.6-1.0-0.50.70.80.60.8-0.81.00.80.80.40.60.70.9
Social responses6.88.712.82.82.9-3.02.93.13.0-2.92.12.8-3.6-1.22.93.22.83.2-3.23.63.33.12.22.83.03.3
Social time0.60.81.3-0.9-0.90.9-0.9-1.0-0.90.9-0.6-0.91.10.4-0.9-1.0-0.9-1.01.0-1.1-1.0-1.0-0.7-0.8-0.9-1.0
Conditioned locomotion1.41.63.8-1.1-1.11.2-1.1-1.3-1.11.1-0.4-1.11.91.5-1.0-1.4-1.1-1.51.5-1.9-1.5-1.3-0.5-1.1-1.1-1.5
Cocaine response after cond. corrected4.45.08.9-2.0-2.02.3-2.1-2.3-2.12.1-1.3-2.03.01.5-2.1-2.5-2.0-2.62.5-3.0-2.6-2.3-1.3-2.0-2.1-2.5
Cocaine response after cond. not corrected4.85.39.8-2.1-2.12.3-2.2-2.4-2.12.1-1.2-2.13.11.7-2.1-2.6-2.1-2.62.6-3.1-2.7-2.4-1.3-2.1-2.1-2.6
Cocaine response before conditioning0.40.50.90.60.6-0.70.70.80.7-0.70.40.6-0.9-0.40.70.80.60.8-0.80.90.80.70.40.60.70.8
Saline control response0.00.10.2-0.2-0.20.2-0.2-0.2-0.20.10.0-0.20.40.4-0.1-0.3-0.2-0.30.3-0.4-0.3-0.2-0.0-0.2-0.2-0.3
Condit. Reinf. active minus inactive responses2.63.24.21.91.9-1.91.91.91.9-1.92.01.9-1.21.01.91.71.91.7-1.71.21.71.82.11.91.91.7
Condit. Reinf. active-inactive response ratio0.40.52.50.70.7-0.50.60.50.7-0.61.10.70.41.60.60.30.70.2-0.2-0.40.10.41.10.70.70.2
Condit. Reinf. active responses2.33.23.51.91.9-1.91.91.91.8-1.81.71.9-1.70.11.81.91.91.8-1.91.71.81.91.71.91.81.8
Condit. Reinf. inactive responses1.11.42.41.11.1-1.21.11.21.0-1.10.71.1-1.6-0.81.11.31.11.3-1.31.61.41.20.71.11.01.3
Condit. Reinf. lever presses2.53.54.12.02.0-1.92.02.02.0-2.02.02.0-1.50.72.01.82.01.8-1.81.51.81.92.02.02.01.9
Condit. Reinf. lever reinforcers received1.82.62.91.71.7-1.71.71.71.7-1.71.61.7-1.40.41.71.61.71.6-1.61.41.61.71.71.71.71.6
Pavlov. Cond. lever latency0.81.21.5-1.0-1.01.1-1.1-1.2-1.11.1-0.8-1.01.20.2-1.1-1.1-1.0-1.21.1-1.2-1.2-1.1-0.9-1.0-1.1-1.2
Pavlov. Cond. magazine entry latency0.50.61.00.70.7-0.80.70.80.8-0.80.50.7-1.0-0.50.70.80.70.9-0.91.00.90.80.50.70.80.9
Pavlov. Cond. change in total contacts0.91.21.61.11.1-1.11.11.31.2-1.31.01.1-1.10.11.11.11.11.1-1.11.11.11.11.01.11.21.2
Pavlov. Cond. index score1.01.31.61.11.1-1.21.11.31.2-1.20.91.1-1.2-0.11.11.21.11.2-1.21.21.21.21.01.11.21.3
Pavlov. Cond. latency score0.91.11.61.01.0-1.11.01.11.1-1.10.81.0-1.2-0.41.01.11.01.1-1.11.21.21.10.81.01.11.2
Pavlov. Cond. lever contacts0.81.21.51.11.1-1.11.11.21.2-1.21.11.1-1.00.21.11.11.11.1-1.11.01.11.11.11.11.21.2
Pavlov. Cond. magazine entry number0.81.01.8-1.0-1.01.0-1.0-1.1-1.01.0-0.6-1.01.30.6-0.9-1.1-1.0-1.11.1-1.3-1.1-1.0-0.7-1.0-1.0-1.2
Pavlov. Cond. intertrial magazine entries0.40.51.5-0.4-0.40.6-0.5-0.8-0.70.7-0.1-0.41.20.9-0.4-0.7-0.4-0.70.7-1.2-0.8-0.6-0.1-0.4-0.7-0.9
Pavlov. Cond. lever-magazine prob. diff.1.01.21.71.11.1-1.11.11.21.2-1.20.91.1-1.3-0.31.11.21.11.2-1.21.31.21.20.91.11.21.3
Pavlov. Cond. response bias2.02.83.41.71.7-1.71.71.81.8-1.81.61.7-1.60.31.71.71.71.7-1.71.61.61.71.61.71.81.8
Conditioned reinforcement - actives2.62.63.01.71.7-1.71.71.61.7-1.51.41.7-1.6-0.41.71.71.61.7-1.71.61.71.71.41.71.71.7
Conditioned reinforcement - inactives0.60.72.1-0.6-0.60.7-0.6-0.8-0.60.7-0.2-0.61.51.3-0.5-0.8-0.6-0.90.9-1.5-0.9-0.8-0.3-0.6-0.6-1.0
Conditioned locomotion7.99.510.73.23.2-3.23.23.23.2-3.12.83.2-2.9-0.03.13.23.33.2-3.22.93.23.22.93.23.23.2
Intermittent access intake day 1-15 change7.17.08.12.82.8-2.82.82.82.8-2.72.62.8-2.20.62.82.72.82.7-2.72.22.72.82.62.82.82.7
Intermittent access intake escalation7.47.39.42.92.9-2.82.92.83.0-2.83.12.9-1.61.62.92.62.92.5-2.61.62.52.73.02.93.02.5
Intermittent access intake escalation 28.88.710.93.23.2-3.13.13.13.2-3.13.33.2-2.01.43.22.93.22.8-2.82.02.83.03.33.23.22.8
Intermitt. access day 1 inactive lever presses0.50.61.10.90.9-0.70.80.80.9-0.81.00.9-0.20.90.70.61.00.6-0.60.20.50.71.00.90.90.6
Intermitt. access day 15 inactive lever presses0.50.50.90.80.8-0.80.80.60.8-0.70.90.8-0.20.80.80.70.90.7-0.70.20.70.70.90.80.80.6
Intermitt. access escalation Index0.50.42.1-0.7-0.70.5-0.6-0.6-0.70.7-1.0-0.7-0.3-1.5-0.7-0.3-0.7-0.30.30.3-0.2-0.5-1.0-0.7-0.7-0.3
Intermittent access day 1 total infusions0.10.10.3-0.3-0.30.3-0.3-0.5-0.20.5-0.3-0.30.4-0.1-0.2-0.2-0.2-0.20.2-0.4-0.2-0.3-0.3-0.3-0.2-0.3
Intermittent access day 15 total infusions2.12.33.11.71.7-1.61.71.41.7-1.41.71.7-0.80.91.81.51.71.5-1.50.81.41.61.71.71.71.4
Intermittent access terminal intake (last 3 days)1.21.31.71.21.2-1.21.21.01.3-1.01.11.2-0.90.11.31.21.31.2-1.20.91.21.21.21.21.31.1
Intermittent access total infusions0.20.30.50.60.6-0.50.60.30.6-0.30.60.6-0.00.50.70.50.60.5-0.50.00.40.50.60.60.60.4
Intermittent access day 1 locomotion0.30.30.50.60.6-0.60.60.40.7-0.40.70.6-0.10.50.70.60.60.5-0.60.10.50.60.60.60.70.5
Intermittent access day 15 total locomotion3.73.94.92.22.2-2.12.11.92.2-1.92.02.2-1.40.72.12.02.22.0-2.01.42.02.02.02.22.21.9
Intermittent access total locomotion1.01.21.51.21.2-1.21.21.01.2-1.01.01.2-0.80.21.21.21.21.1-1.10.81.11.11.01.21.21.1
Intermittent access standard deviation3.43.64.52.12.1-2.02.01.92.1-1.92.02.1-1.40.62.11.92.11.9-1.91.41.82.02.12.12.11.9
Cocaine induced anxiety0.70.82.20.60.6-0.80.70.90.6-0.70.10.6-1.5-1.40.60.90.61.0-1.01.51.00.80.20.60.61.0
Post-drug Anxiety0.50.63.90.30.3-0.50.30.60.3-0.4-0.30.3-1.5-2.00.30.70.30.7-0.71.50.80.5-0.20.30.30.8
Baseline Anxiety0.10.10.30.30.3-0.20.30.10.2-0.20.50.30.20.60.30.10.30.1-0.1-0.20.10.20.50.30.20.1
Lifetime Intake0.10.10.20.30.3-0.30.30.10.4-0.00.30.3-0.00.10.50.30.30.3-0.30.00.30.30.30.30.40.2
Incentive Sensitization - Responses0.50.50.80.80.8-0.60.70.70.8-0.70.90.8-0.40.30.70.60.70.5-0.50.40.50.70.90.80.80.6
Incentive Sensitization - Breakpoint0.50.50.70.80.8-0.70.70.70.8-0.70.80.8-0.50.10.70.60.70.6-0.60.50.60.70.90.80.80.7
Progressive ratio test 1 active lever presses0.10.10.5-0.2-0.20.3-0.2-0.4-0.20.4-0.0-0.20.70.6-0.1-0.3-0.2-0.40.4-0.7-0.4-0.3-0.1-0.2-0.2-0.4
Progressive ratio test 1 breakpoint0.20.20.5-0.3-0.30.4-0.3-0.6-0.30.5-0.2-0.30.70.4-0.2-0.4-0.3-0.50.4-0.7-0.5-0.4-0.2-0.3-0.3-0.5
Progressive ratio test 1 inactive lever presses0.00.00.00.10.1-0.10.1-0.00.10.10.10.10.00.10.10.10.20.1-0.1-0.00.10.10.00.10.10.0
Progressive ratio test 2 active lever presses0.30.30.60.70.7-0.60.60.50.7-0.50.80.7-0.10.50.70.50.60.5-0.50.10.40.60.80.70.70.5
Progressive ratio test 2 breakpoint0.30.40.50.70.7-0.60.60.60.7-0.50.60.7-0.5-0.10.70.60.70.6-0.60.50.60.70.60.70.70.6
Progressive ratio test 2 inactive lever presses0.00.10.10.20.2-0.30.20.20.3-0.10.20.2-0.2-0.10.30.30.30.3-0.30.20.30.30.10.20.30.2
Total sessions with >9 infusions0.10.11.2-0.1-0.10.0-0.1-0.1-0.10.3-0.4-0.1-0.5-1.10.00.1-0.10.2-0.10.50.10.0-0.3-0.1-0.10.1
Short access day 1 total inactive lever presses0.00.00.10.20.2-0.20.20.20.2-0.20.20.2-0.10.10.30.20.20.2-0.20.10.20.20.20.20.20.2
Short access day 10 total inactive lever presses0.10.20.70.40.4-0.30.40.40.4-0.50.60.40.20.80.30.20.60.2-0.2-0.20.20.30.60.40.40.2
Short access day 1 total infusions0.10.11.10.10.1-0.30.20.10.20.1-0.20.1-0.7-1.10.30.40.20.4-0.40.70.40.3-0.10.10.20.3
Short access day 10 total infusions0.00.00.10.20.2-0.10.2-0.10.20.10.20.20.1-0.10.30.10.30.1-0.1-0.10.10.10.30.20.20.1
Short access total infusions0.00.00.6-0.0-0.0-0.0-0.0-0.20.00.3-0.2-0.0-0.2-0.80.10.1-0.00.1-0.10.20.10.0-0.1-0.00.00.1
Short access day 1 locomotion0.70.81.30.90.9-1.00.90.60.9-0.50.50.9-0.8-0.31.01.11.01.1-1.10.81.10.90.50.90.90.9
Short access day 10 total locomotion4.54.96.12.42.4-2.32.42.22.4-2.22.32.4-1.60.82.52.32.42.2-2.21.62.22.32.32.42.42.2
Short access total locomotion0.91.01.31.01.0-1.11.00.81.1-0.70.81.0-0.9-0.21.11.11.01.1-1.10.91.11.00.81.01.11.0
Compulsive drug intake1.11.11.6-1.2-1.21.1-1.2-0.9-1.20.9-1.2-1.20.7-0.3-1.2-1.1-1.3-1.01.0-0.7-1.0-1.1-1.3-1.2-1.2-1.0
One hour access (0.3 mA shock)0.20.20.6-0.4-0.40.4-0.4-0.7-0.40.7-0.3-0.40.80.3-0.3-0.5-0.4-0.50.5-0.8-0.5-0.5-0.4-0.4-0.4-0.6
One hour access (shock baseline)0.10.10.70.40.4-0.30.40.10.4-0.10.60.40.40.80.50.20.40.2-0.2-0.40.20.30.50.40.40.1
Number of responses in last shaping day0.20.20.40.40.4-0.50.50.40.4-0.40.30.4-0.4-0.10.60.50.50.5-0.50.40.50.50.30.40.40.4
Context. condit. distance diff. score0.30.30.5-0.5-0.50.6-0.6-0.7-0.60.7-0.4-0.60.70.2-0.6-0.6-0.5-0.60.6-0.7-0.6-0.6-0.4-0.5-0.6-0.7
Locomotion velocity, session 10.50.61.80.50.5-0.60.50.70.6-0.6-0.10.4-1.3-1.30.40.80.50.9-0.91.30.90.7-0.00.50.60.9
Locomotion distance, session 10.20.33.2-0.1-0.1-0.1-0.10.1-0.10.0-0.8-0.2-1.0-1.8-0.20.3-0.10.4-0.41.00.40.1-0.7-0.1-0.10.3
Locomotion velocity, session 22.83.37.11.61.6-1.81.61.91.6-1.70.71.5-2.7-1.91.52.01.62.1-2.12.72.21.80.81.61.62.1
Locomotion distance, session 21.21.74.61.01.0-1.21.01.30.9-1.00.10.9-2.1-2.00.91.41.01.5-1.52.11.61.20.21.00.91.5
Locomotion velocity, session 36.07.08.12.72.7-2.82.72.82.8-2.82.42.7-2.50.12.72.72.72.7-2.72.52.72.82.42.72.82.8
Locomotion distance, session 30.00.00.00.10.1-0.00.10.20.2-0.20.10.0-0.00.20.00.00.10.0-0.00.00.00.00.10.10.20.1
Stereotopy head waving bouts, day 34.25.06.32.22.2-2.32.32.42.2-2.21.72.2-2.5-0.72.22.42.22.5-2.52.52.52.41.82.22.22.4
Stereotopy head waving duration, day 35.16.17.22.52.5-2.62.52.62.5-2.52.02.5-2.6-0.52.52.72.52.7-2.72.62.72.62.12.52.52.7
Locomotion velocity, session 70.70.81.20.80.8-0.90.90.90.8-0.90.60.8-1.1-0.50.81.00.81.0-1.01.11.00.90.60.80.81.0
Locomotion distance, session 70.10.10.7-0.1-0.10.2-0.1-0.1-0.00.00.3-0.10.50.9-0.1-0.3-0.1-0.30.3-0.5-0.3-0.20.2-0.1-0.0-0.2
Stereotopy head waving bouts, day 70.20.22.0-0.3-0.30.1-0.2-0.2-0.20.3-0.7-0.3-0.5-1.4-0.30.1-0.30.1-0.10.50.2-0.1-0.7-0.3-0.20.1
Stereotopy head waving duration, day 70.20.32.50.10.1-0.30.10.20.1-0.0-0.50.1-0.9-1.60.10.50.10.6-0.50.90.60.3-0.40.10.10.4
Locomotion velocity, session 80.50.53.70.30.3-0.50.30.40.3-0.2-0.40.3-1.4-1.90.30.70.30.8-0.81.40.90.5-0.40.30.30.7
Locomotion distance, session 80.10.10.40.20.2-0.20.20.30.1-0.2-0.10.2-0.6-0.60.20.30.20.4-0.40.60.40.3-0.00.20.10.3
Degree of sensitization distance0.40.40.5-0.6-0.60.6-0.6-0.7-0.70.7-0.6-0.60.6-0.0-0.6-0.6-0.6-0.60.6-0.6-0.6-0.6-0.6-0.6-0.7-0.7
Degree of sensitization stereotypy2.12.23.3-1.6-1.61.5-1.6-1.6-1.61.6-1.8-1.60.9-1.1-1.6-1.4-1.6-1.31.3-0.9-1.3-1.5-1.8-1.6-1.6-1.4
Condit. Reinf. active minus inactive responses4.04.45.12.22.2-2.22.22.22.1-2.21.82.1-2.2-0.32.12.22.22.2-2.22.22.22.21.82.22.12.2
Condit. Reinf. active-inactive response ratio2.32.52.81.71.7-1.61.71.71.7-1.71.71.6-1.20.61.61.51.71.5-1.51.21.51.61.71.71.71.6
Condit. Reinf. active responses3.23.95.81.91.9-2.01.92.11.9-1.91.31.9-2.4-1.11.92.21.92.2-2.22.42.22.11.41.91.92.2
Condit. Reinf. inactive responses0.70.82.10.70.7-0.80.70.80.6-0.70.10.6-1.5-1.40.61.00.71.1-1.01.51.10.80.10.70.61.0
Incentive salience index mean1.92.33.71.51.5-1.61.51.61.4-1.40.91.4-1.9-1.01.41.71.51.7-1.71.91.71.61.01.51.41.7
Condit. Reinf. lever presses0.30.44.2-0.2-0.20.1-0.2-0.1-0.30.3-1.0-0.4-0.9-2.0-0.40.2-0.20.3-0.30.90.3-0.0-0.9-0.2-0.30.2
Time in familiar zone, hab. session 12.22.12.51.51.5-1.51.51.61.5-1.61.51.6-1.20.51.61.41.51.4-1.41.21.41.51.51.51.51.5
Time in novel zone, hab. session 11.21.22.1-1.1-1.11.1-1.2-1.1-1.21.2-1.5-1.20.5-1.2-1.2-0.9-1.1-0.80.9-0.5-0.8-1.0-1.4-1.1-1.2-1.0
Total zone transitions, hab. session 10.71.02.70.80.8-0.90.81.00.7-0.80.10.7-1.6-1.50.71.10.81.2-1.21.61.21.00.20.80.71.1
Total locomotion distance, hab. session 10.91.35.70.60.6-0.90.71.00.6-0.8-0.30.6-2.1-2.40.61.20.61.3-1.32.11.40.9-0.20.60.61.3
Locomotion velocity, hab. session 11.21.74.61.01.0-1.21.01.31.0-1.10.21.0-2.1-1.91.01.41.01.5-1.52.11.61.20.21.01.01.5
Time in familiar zone, hab. session 26.56.88.02.72.7-2.72.82.82.8-2.82.82.8-2.11.02.82.62.72.5-2.52.12.52.72.82.72.82.6
Time in novel zone, hab. session 25.05.06.4-2.4-2.42.3-2.4-2.4-2.42.4-2.5-2.41.6-1.2-2.4-2.1-2.4-2.12.1-1.6-2.1-2.3-2.5-2.4-2.4-2.2
Total zone transitions, hab. session 20.50.73.4-0.8-0.80.7-0.8-0.6-0.90.7-1.4-0.8-0.4-1.8-0.8-0.4-0.8-0.30.30.4-0.3-0.6-1.3-0.8-0.9-0.4
Total locomotion distance, hab. session 20.70.92.50.70.7-0.80.71.00.7-0.90.10.7-1.6-1.30.71.00.71.1-1.11.61.10.90.20.70.71.1
Locomotion velocity, hab. session 20.60.92.80.60.6-0.80.60.90.6-0.7-0.10.6-1.7-1.70.61.00.61.1-1.11.71.10.8-0.00.60.61.1
Novel to familiar place preference ratio4.34.56.5-2.3-2.32.2-2.3-2.2-2.22.3-2.5-2.31.3-1.5-2.3-2.0-2.3-1.91.9-1.3-1.9-2.1-2.5-2.3-2.2-2.0
Novelty place preference2.62.74.3-1.8-1.81.7-1.8-1.7-1.71.8-2.1-1.90.9-1.4-1.9-1.5-1.8-1.41.4-0.9-1.4-1.7-2.1-1.8-1.7-1.5
Time in novel zone, NPP test2.93.14.6-1.9-1.91.8-1.9-1.8-1.81.9-2.1-2.01.0-1.3-2.0-1.6-1.9-1.61.6-1.0-1.5-1.8-2.1-1.9-1.8-1.6
Total zone transitions, NPP test0.10.10.9-0.3-0.30.2-0.3-0.2-0.40.2-0.6-0.3-0.3-0.9-0.3-0.1-0.3-0.10.10.3-0.0-0.2-0.6-0.3-0.4-0.1
Total locomotion distance, NPP test0.20.31.9-0.5-0.50.3-0.4-0.2-0.50.3-0.9-0.5-0.5-1.4-0.5-0.2-0.5-0.10.10.5-0.1-0.3-0.9-0.5-0.5-0.1
Locomotion velocity, NPP test0.10.21.7-0.2-0.20.0-0.10.1-0.20.0-0.6-0.2-0.7-1.3-0.20.1-0.20.2-0.20.70.2-0.0-0.6-0.2-0.20.2
Pavlov. Cond. lever latency0.20.21.80.40.4-0.20.30.20.3-0.30.80.40.51.30.40.00.4-0.00.0-0.5-0.10.20.80.40.30.0
Pavlov. Cond. magazine entry latency2.73.54.12.02.0-2.02.02.01.9-1.91.92.0-1.70.32.01.92.01.9-1.91.71.92.01.92.01.91.9
Pavlov. Cond. change in total contacts0.00.00.10.20.2-0.20.20.30.2-0.30.10.2-0.3-0.20.20.20.20.2-0.20.30.20.20.10.20.20.3
Pavlov. Cond. index score0.30.40.90.50.5-0.60.50.60.5-0.50.10.5-1.0-0.90.50.70.50.7-0.71.00.80.60.20.50.50.7
Pavlov. Cond. latency score0.30.41.50.40.4-0.50.40.50.4-0.4-0.10.4-1.1-1.20.40.70.40.7-0.71.10.80.5-0.10.40.40.7
Pavlov. Cond. lever contacts0.20.22.5-0.2-0.20.0-0.10.0-0.10.1-0.7-0.2-0.8-1.6-0.20.2-0.20.3-0.30.80.30.0-0.7-0.2-0.10.3
Pavlov. Cond. magazine entry number0.60.70.8-0.9-0.90.9-0.9-0.9-0.80.8-0.8-0.90.80.1-0.9-0.9-0.9-0.90.9-0.8-0.9-0.9-0.8-0.9-0.8-0.9
Pavlov. Cond. intertrial magazine entries0.20.30.90.60.6-0.40.50.40.4-0.50.80.60.11.00.60.30.60.2-0.3-0.10.20.40.80.60.40.2
Pavlov. Cond. lever-magazine prob. diff.0.60.81.40.80.8-0.90.80.90.8-0.80.40.8-1.2-0.80.81.00.81.0-1.01.21.00.90.40.80.81.0
Pavlov. Cond. response bias1.01.21.31.11.1-1.11.11.21.1-1.10.91.1-1.1-0.21.11.21.11.2-1.21.11.21.10.91.11.11.2
Bone: apparent density0.50.86.6-0.6-0.60.3-0.5-0.3-0.60.6-1.5-0.6-1.2-2.6-0.60.0-0.60.2-0.11.20.2-0.3-1.4-0.6-0.60.1
Bone surface0.81.414.0-0.3-0.3-0.1-0.20.1-0.30.3-1.6-0.3-2.2-3.7-0.30.7-0.30.8-0.82.20.90.2-1.5-0.3-0.30.7
Bone volume0.81.413.9-0.3-0.3-0.1-0.20.1-0.30.3-1.6-0.3-2.2-3.7-0.30.7-0.30.9-0.82.20.90.2-1.5-0.3-0.30.7
Bone: connectivity density0.50.93.9-1.0-1.00.7-0.9-0.6-0.90.8-1.6-1.0-0.6-2.0-1.0-0.4-1.0-0.30.40.6-0.3-0.7-1.5-1.0-0.9-0.3
Bone: cortical apparent density0.91.11.7-1.0-1.01.1-1.0-1.3-1.21.3-0.9-1.01.20.1-1.0-1.1-1.0-1.11.1-1.2-1.1-1.1-0.9-1.0-1.2-1.3
Bone: cortical area0.71.12.3-1.1-1.11.0-1.1-1.1-1.21.2-1.5-1.10.2-1.5-1.1-0.8-1.1-0.70.7-0.2-0.7-1.0-1.5-1.1-1.2-0.8
Bone: cortical porosity0.50.51.00.60.6-0.70.70.70.6-0.60.30.6-1.0-0.60.60.80.60.8-0.81.00.90.70.30.60.60.8
Bone: cortical porosity0.10.11.1-0.1-0.1-0.0-0.1-0.0-0.10.1-0.5-0.1-0.6-1.1-0.10.2-0.10.2-0.20.60.30.0-0.5-0.1-0.10.2
Bone: cortical thickness1.21.92.5-1.5-1.51.4-1.5-1.5-1.61.6-1.6-1.51.0-0.6-1.5-1.3-1.5-1.31.3-1.0-1.3-1.4-1.5-1.5-1.6-1.4
Bone: cortical thickness0.10.10.60.30.3-0.20.20.10.2-0.20.50.30.30.80.30.00.3-0.0-0.0-0.3-0.00.10.50.30.20.0
Bone: cortical tissue density0.60.81.2-0.8-0.80.9-0.8-1.1-0.91.1-0.7-0.81.10.2-0.8-0.9-0.8-0.90.9-1.1-0.9-0.9-0.7-0.8-0.9-1.1
Bone: elastic displacement0.30.30.40.50.5-0.60.50.60.6-0.60.40.5-0.7-0.10.50.60.50.6-0.60.70.60.60.40.50.60.7
Bone: elastic work0.20.30.6-0.6-0.60.5-0.6-0.5-0.60.5-0.8-0.60.1-0.5-0.6-0.4-0.6-0.40.4-0.1-0.4-0.5-0.7-0.6-0.6-0.4
Bone: endosteal estimation0.20.51.0-0.8-0.80.7-0.8-0.8-0.80.8-1.0-0.80.2-0.8-0.8-0.6-0.8-0.60.6-0.2-0.5-0.7-1.0-0.8-0.8-0.6
Bone: endosteal perimeter0.20.51.80.40.4-0.60.50.50.4-0.4-0.10.4-1.2-1.30.40.80.40.8-0.81.20.90.6-0.00.40.40.7
Bone: final force1.42.23.5-1.6-1.61.5-1.6-1.6-1.71.7-1.9-1.60.7-1.3-1.6-1.3-1.6-1.31.3-0.7-1.2-1.5-1.8-1.6-1.7-1.3
Bone: final moment1.11.82.9-1.4-1.41.3-1.4-1.4-1.51.5-1.7-1.40.6-1.2-1.4-1.2-1.4-1.11.1-0.6-1.1-1.3-1.7-1.4-1.5-1.2
Bone: marrow area0.30.61.0-0.8-0.80.7-0.8-0.8-0.80.9-1.0-0.80.3-0.8-0.8-0.6-0.8-0.60.6-0.3-0.6-0.7-1.0-0.8-0.8-0.6
Bone: maximum diameter0.61.02.70.80.8-1.00.80.80.7-0.60.10.8-1.6-1.60.81.20.81.3-1.21.61.31.00.20.80.71.1
Bone: maximum force1.32.33.2-1.6-1.61.5-1.6-1.6-1.71.7-1.8-1.60.9-1.0-1.6-1.4-1.6-1.31.4-0.9-1.3-1.5-1.8-1.6-1.7-1.5
Bone: maximum moment1.11.92.7-1.5-1.51.4-1.5-1.5-1.61.6-1.7-1.50.8-1.0-1.5-1.3-1.5-1.21.2-0.8-1.2-1.4-1.6-1.5-1.6-1.3
Bone: minimum diameter0.10.11.2-0.3-0.30.2-0.2-0.3-0.30.4-0.6-0.3-0.4-1.1-0.3-0.0-0.30.1-0.00.40.1-0.1-0.6-0.3-0.3-0.1
Bone: periosteal estimation0.51.02.5-1.1-1.10.9-1.0-1.1-1.21.2-1.5-1.10.0-1.6-1.1-0.7-1.1-0.60.6-0.0-0.6-0.9-1.5-1.1-1.2-0.8
Bone: periosteal perimeter0.20.32.6-0.0-0.0-0.10.00.0-0.10.2-0.6-0.0-0.9-1.6-0.00.4-0.00.4-0.40.90.50.2-0.6-0.0-0.10.3
Bone: post-yield work0.60.81.1-0.8-0.80.9-0.9-1.0-1.01.0-0.7-0.81.00.0-0.8-0.9-0.8-0.90.9-1.0-0.9-0.9-0.7-0.8-1.0-1.0
Bone: stiffness3.25.06.1-2.3-2.32.3-2.4-2.4-2.52.4-2.4-2.31.8-0.7-2.3-2.2-2.4-2.22.2-1.8-2.2-2.3-2.3-2.3-2.5-2.3
Bone: tissue strength1.81.72.2-1.4-1.41.4-1.4-1.5-1.51.5-1.3-1.41.1-0.3-1.4-1.3-1.4-1.31.3-1.1-1.3-1.4-1.3-1.4-1.5-1.4
Bone: trabecular number0.61.03.30.60.6-0.80.70.90.7-0.7-0.10.6-1.8-1.80.61.10.61.1-1.11.81.20.8-0.10.60.71.2
Bone: trabecular spacing0.60.76.1-0.1-0.10.4-0.2-0.3-0.10.10.8-0.11.72.5-0.1-0.8-0.1-0.90.9-1.7-0.9-0.50.7-0.1-0.1-0.8
Bone: trabecular thickness1.01.211.1-0.7-0.70.3-0.6-0.4-0.70.7-1.8-0.7-1.6-3.3-0.70.2-0.70.4-0.31.60.4-0.2-1.7-0.7-0.70.2
Bone: trabecular tissue density1.82.55.1-1.4-1.41.6-1.4-1.8-1.61.6-0.8-1.42.31.3-1.4-1.7-1.4-1.81.8-2.3-1.8-1.6-0.8-1.4-1.6-1.9
Breakpoint value in progressive ratio session5.76.37.62.62.6-2.62.72.62.7-2.62.62.7-2.00.62.72.52.82.5-2.52.02.52.62.72.72.72.5
Distance traveled before self-admin0.30.30.5-0.5-0.50.6-0.6-0.5-0.60.5-0.7-0.60.2-0.5-0.7-0.5-0.6-0.50.5-0.2-0.5-0.5-0.7-0.6-0.6-0.5
Distance traveled after self-admin0.80.91.31.01.0-0.90.91.10.9-1.00.70.9-1.1-0.40.81.01.11.0-1.01.11.01.00.70.90.91.1
Delta time in closed arm before/after self-admin0.60.64.2-0.3-0.30.5-0.3-0.4-0.30.20.5-0.31.52.1-0.2-0.8-0.4-0.90.9-1.5-1.0-0.60.4-0.3-0.3-0.8
Delta time in open arm before/after self-admin1.41.31.7-1.2-1.21.2-1.2-1.2-1.21.2-1.2-1.21.0-0.2-1.3-1.1-1.1-1.11.1-1.0-1.1-1.2-1.2-1.2-1.2-1.2
Diff in mean of infusions in LGA sessions1.61.82.01.41.4-1.41.41.41.4-1.41.31.4-1.20.11.41.41.21.4-1.41.21.41.41.31.41.41.4
Extinction: sum of active levers before priming1.71.72.91.41.4-1.31.41.31.4-1.31.71.4-0.61.21.51.11.51.1-1.10.61.01.31.71.41.41.1
Active lever presses in extinction session 63.23.14.21.81.8-1.81.81.81.8-1.71.51.8-1.8-0.31.81.92.11.9-1.91.81.81.81.61.81.81.9
Delta distance traveled before/after self-admin1.51.62.11.31.3-1.31.31.31.3-1.31.11.3-1.3-0.11.31.41.41.4-1.41.31.41.31.11.31.31.3
Delta ambulatory time before/after self-admin1.61.82.41.31.3-1.41.31.41.3-1.31.01.3-1.5-0.61.31.41.41.5-1.51.51.51.41.01.31.31.4
Time in closed arm before self-admin1.11.22.3-1.3-1.31.1-1.2-1.1-1.21.2-1.5-1.20.4-1.1-1.1-0.9-1.2-0.90.9-0.4-0.8-1.1-1.5-1.2-1.2-1.0
Time in closed arm after self-admin0.00.00.00.10.1-0.10.10.20.0-0.20.20.0-0.10.10.20.0-0.00.0-0.00.10.00.10.10.00.00.1
Time in open arm before self-admin1.21.31.51.21.2-1.21.21.21.2-1.21.21.2-0.90.41.11.11.11.1-1.10.91.11.21.21.21.21.1
Time in open arm after self-admin0.70.71.1-0.8-0.80.9-0.9-0.9-0.80.8-0.7-0.71.10.5-1.0-0.9-0.8-0.90.9-1.1-0.9-0.9-0.7-0.7-0.8-0.9
Sum of active levers in priming session hrs 5-60.00.00.10.10.1-0.00.1-0.00.10.00.10.10.10.20.10.00.1-0.00.0-0.1-0.00.00.10.10.1-0.0
Time to tail flick, vehicle, before self-admin0.60.62.70.40.4-0.60.50.70.5-0.6-0.10.5-1.5-1.70.40.80.40.8-0.81.50.80.60.00.50.50.9
Time to tail flick, vehicle, after self-admin0.20.20.90.40.4-0.30.40.50.4-0.50.80.40.10.90.40.20.40.1-0.1-0.10.10.30.80.40.40.3
Time to tail flick, test, before self-admin0.30.32.50.00.0-0.30.20.20.1-0.0-0.30.2-1.0-1.60.20.4-0.10.5-0.51.00.50.3-0.30.20.10.5
Time to tail flick, test, after self-admin0.20.21.10.30.3-0.40.30.30.3-0.2-0.00.3-0.8-1.00.30.50.20.5-0.50.80.50.30.00.30.30.5
Delta time to tail flick, vehicle, before/after SA0.50.53.0-0.4-0.40.5-0.4-0.5-0.40.30.3-0.41.31.7-0.3-0.7-0.3-0.80.8-1.3-0.9-0.60.2-0.4-0.4-0.8
Delta time to tail flick, test, before/after SA0.20.21.00.50.5-0.40.40.40.5-0.50.70.50.11.00.50.30.50.2-0.2-0.10.20.30.60.50.50.3
Ambulatory time before self-admin0.20.20.4-0.4-0.50.5-0.5-0.4-0.40.5-0.6-0.50.3-0.3-0.6-0.5-0.5-0.50.5-0.3-0.5-0.5-0.5-0.5-0.4-0.4
Ambulatory time after self-admin0.50.50.80.80.8-0.70.70.80.7-0.70.50.7-0.8-0.30.60.70.90.8-0.70.80.80.80.60.70.70.8
Total heroin consumption1.92.32.71.51.6-1.61.61.51.5-1.41.31.6-1.6-0.41.61.61.61.6-1.61.61.61.61.41.61.51.6
Area under the delay curve2.32.43.1-1.6-1.61.6-1.7-1.6-1.61.6-1.7-1.61.2-0.6-1.8-1.6-1.6-1.51.5-1.2-1.5-1.6-1.7-1.6-1.6-1.5
Delay disc. indifference point, 0s delay7.98.612.0-3.1-3.13.0-3.1-3.1-3.13.1-3.4-3.22.0-1.9-3.1-2.8-3.2-2.72.7-2.0-2.6-2.9-3.5-3.2-3.1-2.8
Delay disc. indifference point, 16s delay0.20.20.3-0.4-0.40.4-0.4-0.4-0.40.4-0.5-0.40.3-0.3-0.5-0.4-0.4-0.40.4-0.3-0.4-0.4-0.4-0.4-0.4-0.4
Delay disc. indifference point, 2s delay6.06.67.9-2.7-2.72.7-2.7-2.7-2.72.7-2.8-2.82.0-1.1-2.7-2.6-2.8-2.52.5-2.0-2.5-2.6-2.8-2.8-2.7-2.5
Delay disc. indifference point, 24s delay0.50.50.8-0.8-0.80.8-0.8-0.7-0.70.7-0.6-0.70.6-0.3-0.9-0.8-0.7-0.80.8-0.6-0.8-0.8-0.6-0.7-0.7-0.7
Delay disc. indifference point, 4s delay1.31.42.4-1.3-1.31.2-1.3-1.2-1.31.2-1.5-1.20.5-1.3-1.4-1.0-1.2-1.01.0-0.5-0.9-1.2-1.5-1.2-1.3-1.0
Delay disc. indifference point, 8s delay1.01.01.5-1.0-1.01.1-1.0-1.0-1.00.9-0.7-1.01.20.6-1.1-1.1-1.0-1.11.1-1.2-1.1-1.1-0.8-1.0-1.0-1.1
Delay discount exponential model param2.02.12.71.51.5-1.51.61.51.5-1.51.61.5-1.20.61.71.51.51.4-1.51.21.41.51.51.51.51.4
Delay discount hyperbolic model param2.93.13.71.91.9-1.81.91.81.8-1.81.91.8-1.40.61.91.81.81.7-1.71.41.71.81.91.81.81.7
Fecal boli incidents, locomotor time 11.61.83.6-1.2-1.21.3-1.2-1.5-1.21.3-0.7-1.21.91.1-1.1-1.5-1.2-1.51.5-1.9-1.5-1.3-0.7-1.2-1.2-1.6
Change in fecal boli incidents, locomotor task0.40.41.90.30.3-0.40.30.40.3-0.3-0.20.3-1.1-1.40.40.60.30.7-0.71.10.70.5-0.20.30.30.6
Time >=10cm from walls, locomotor time 10.40.41.2-0.6-0.60.6-0.7-0.7-0.70.7-1.0-0.70.1-1.1-0.7-0.5-0.7-0.40.4-0.1-0.4-0.6-0.9-0.7-0.7-0.5
Bouts of movement, locomotor time 10.20.20.30.50.5-0.50.50.40.5-0.40.50.5-0.30.20.50.40.50.4-0.40.30.40.50.50.50.50.4
Total resting periods, locomotor time 10.20.20.30.60.6-0.50.50.40.5-0.40.50.5-0.4-0.00.50.50.50.5-0.50.40.50.50.50.50.50.5
Rest time, locomotor task time 10.20.20.30.50.5-0.40.40.40.4-0.30.20.4-0.5-0.50.40.50.40.5-0.50.50.50.50.30.40.40.4
Distance moved, locomotor task time 10.60.61.4-0.9-0.90.7-0.8-0.7-0.80.8-1.2-0.80.1-1.1-0.9-0.6-0.8-0.50.5-0.1-0.5-0.8-1.2-0.8-0.8-0.6
Vertical activity count, locomotor time 10.00.10.2-0.2-0.20.2-0.2-0.2-0.20.1-0.1-0.20.30.4-0.2-0.2-0.2-0.30.3-0.3-0.3-0.2-0.1-0.2-0.2-0.2
Time >=10cm from walls, locomotor time 20.91.01.6-0.8-0.81.0-1.0-1.1-0.91.0-0.6-0.91.30.6-1.0-1.1-0.9-1.11.1-1.3-1.1-1.0-0.6-0.9-0.9-1.1
Bouts of movement, locomotor time 20.30.41.20.40.4-0.50.40.60.4-0.4-0.10.4-1.0-1.10.40.70.40.7-0.71.00.70.5-0.00.40.40.7
Total resting periods, locomotor time 20.30.31.70.40.4-0.50.40.50.3-0.4-0.20.3-1.1-1.30.30.60.30.7-0.71.10.70.5-0.10.30.30.6
Rest time, locomotor task time 20.40.51.00.70.7-0.70.60.60.6-0.50.30.6-1.0-0.90.60.80.60.8-0.81.00.90.70.30.60.60.8
Distance moved, locomotor task time 20.70.81.5-0.8-0.80.9-0.8-0.9-0.80.8-0.4-0.81.20.9-0.8-1.0-0.8-1.01.0-1.2-1.0-0.9-0.5-0.8-0.8-1.0
Vertical activity count, locomotor time 20.60.72.1-0.5-0.50.7-0.6-0.8-0.60.7-0.0-0.61.41.4-0.5-0.9-0.6-1.01.0-1.4-1.0-0.7-0.1-0.6-0.6-1.0
Weight adjusted by age0.20.20.6-0.4-0.40.4-0.3-0.4-0.30.30.1-0.30.80.7-0.2-0.6-0.4-0.60.6-0.8-0.7-0.40.1-0.4-0.3-0.5
Seeking ratio, delayed vs. immediate footshock4.65.27.12.22.2-2.42.32.52.3-2.31.72.2-2.7-0.72.22.52.22.5-2.52.72.52.41.72.22.32.6
Locomotion in novel chamber0.50.61.10.80.8-0.70.80.90.9-0.91.00.8-0.60.30.80.70.80.6-0.60.60.60.81.00.90.90.8
Locomotion in novel chamber post-restriction0.80.91.30.91.0-1.01.01.00.9-0.90.91.0-1.0-0.01.11.01.01.0-1.01.01.01.00.91.00.91.0
Progressive ratio0.10.20.4-0.3-0.40.4-0.4-0.3-0.20.2-0.1-0.40.50.4-0.4-0.5-0.4-0.60.6-0.5-0.6-0.4-0.1-0.4-0.2-0.4
Food seeking constrained by brief footshock0.10.10.20.30.3-0.30.30.30.2-0.30.30.3-0.3-0.10.40.30.30.3-0.30.30.30.30.30.30.20.3
Seeking ratio, punishment vs. effort0.10.10.20.30.3-0.40.30.20.1-0.10.10.3-0.3-0.20.50.40.30.4-0.40.30.40.30.10.30.10.2
Run reversals in cocaine runway, females0.50.51.30.60.5-0.60.60.70.5-0.60.20.5-1.1-0.90.50.70.50.8-0.71.10.80.70.30.50.50.8
Run reversals in cocaine runway, males1.11.11.91.01.0-1.01.01.00.9-0.90.60.9-1.4-0.81.11.11.01.2-1.21.41.21.10.71.00.91.1
Latency to leave start box in cocaine runway0.91.02.20.80.9-0.90.80.80.8-0.60.20.9-1.5-1.40.71.10.91.2-1.21.51.21.00.30.90.81.1
Latency to leave start box in cocaine runway, F0.40.44.6-0.3-0.20.1-0.3-0.3-0.40.6-1.0-0.2-0.8-2.1-0.20.2-0.20.3-0.20.80.3-0.0-0.9-0.2-0.40.1
Latency to leave start box in cocaine runway, M3.43.34.51.91.9-1.81.92.02.0-2.02.12.0-1.21.11.71.71.91.6-1.61.21.61.82.11.92.01.8
Cd content in liver0.20.20.3-0.5-0.50.5-0.5-0.5-0.50.5-0.5-0.50.3-0.2-0.5-0.4-0.5-0.40.4-0.3-0.4-0.5-0.5-0.5-0.5-0.5
Co content in liver0.60.70.90.90.9-0.90.90.90.9-0.91.00.9-0.50.60.90.80.90.8-0.80.50.80.91.00.90.90.8
Cu content in liver0.20.31.3-0.5-0.50.4-0.5-0.4-0.50.5-0.9-0.5-0.2-1.2-0.6-0.2-0.5-0.20.20.2-0.1-0.4-0.8-0.5-0.5-0.2
Fe content in liver0.10.10.50.20.2-0.20.20.20.2-0.20.50.20.20.70.30.10.20.0-0.1-0.20.00.20.40.20.20.1
K content in liver0.10.11.3-0.2-0.20.1-0.2-0.1-0.20.2-0.6-0.2-0.5-1.1-0.30.0-0.20.1-0.10.50.1-0.1-0.6-0.2-0.20.1
Mg content in liver0.20.22.1-0.2-0.20.1-0.3-0.1-0.20.2-0.7-0.3-0.6-1.5-0.40.0-0.20.1-0.10.60.1-0.1-0.7-0.2-0.20.1
Mn content in liver1.01.16.10.50.5-0.80.50.70.5-0.5-0.50.5-2.0-2.50.51.10.51.2-1.22.01.30.8-0.40.50.51.1
Na content in liver1.21.21.9-1.2-1.21.1-1.2-1.2-1.21.2-1.4-1.20.7-0.7-1.2-1.0-1.2-1.01.0-0.7-0.9-1.1-1.4-1.2-1.2-1.0
Rb content in liver0.60.72.1-0.9-0.90.8-0.9-0.8-0.90.9-1.3-0.9-0.0-1.5-0.9-0.6-0.9-0.50.50.0-0.5-0.7-1.3-0.9-0.9-0.6
Se content in liver0.10.20.30.40.4-0.40.40.40.4-0.40.30.4-0.5-0.30.40.50.40.5-0.50.50.50.40.30.40.40.5
Sr content in liver0.20.21.90.30.3-0.20.30.20.3-0.30.70.30.51.40.3-0.00.3-0.10.1-0.5-0.10.10.60.30.3-0.0
Zn content in liver2.62.95.31.91.9-1.71.81.81.9-1.92.31.9-0.61.81.81.41.91.3-1.30.61.31.62.31.91.91.4