Hub : Genes

Sgta

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000019891 0.1 0.07 9.8e-10 0.07 0.08 0.07 0.08 3.7e-08 3.1e-09 1.1e-08 7.5e-09
2 Adipose mRNA stability ENSRNOG00000019891 0.03 0.03 2.4e-04 0.03 0.02 0.02 0.02 3.4e-04 9.8e-04 1.4e-03 1.9e-03
3 BLA isoform ratio ENSRNOT00000026960 0.04 0.03 7.4e-03 0.02 0.03 0.02 0.03 3.9e-02 7.5e-03 3.3e-02 1.4e-02
4 Brain gene expression ENSRNOG00000019891 0.03 0.02 8.0e-03 0.02 0.01 0.01 0.01 8.5e-03 1.6e-02 2.6e-02 1.9e-02
5 IL gene expression ENSRNOG00000019891 0.15 0.11 2.7e-03 0.07 0.03 -0.01 0.02 1.1e-02 6.4e-02 5.6e-01 1.1e-01
6 Liver alternative TSS ENSRNOT00000105493 0.08 0.06 7.0e-05 0.03 0.04 0.04 0.04 3.5e-04 2.2e-05 2.5e-05 7.7e-05
7 Liver gene expression ENSRNOG00000019891 0.04 0.03 6.7e-06 0.04 0.04 0.03 0.04 1.3e-05 7.5e-05 3.4e-04 3.6e-05
8 Liver intron excision ratio chr7:8663357:8663524 0.02 0.02 3.1e-03 0 0.01 0 0 1.5e-01 4.3e-02 8.6e-02 1.6e-01
9 Liver intron excision ratio chr7:8663357:8663527 0.03 0.02 2.9e-03 0 0.01 0.01 0 1.4e-01 3.1e-02 4.5e-02 1.0e-01
10 PL alternative polyA ENSRNOT00000110762 0.02 0.02 8.4e-03 0.02 0.02 0.02 0.02 6.3e-03 1.3e-02 1.7e-02 1.2e-02
11 PL gene expression ENSRNOG00000019891 0.1 0.07 8.3e-09 0.09 0.11 0.12 0.11 3.0e-07 7.9e-09 5.0e-09 7.1e-09
12 PL intron excision ratio chr7:8663357:8663524 0.03 0.02 4.8e-03 0.03 0.03 0.04 0.03 4.1e-03 3.5e-03 3.2e-04 5.2e-03
13 PL intron excision ratio chr7:8663357:8663527 0.03 0.02 5.0e-03 0.03 0.03 0.04 0.02 4.6e-03 3.8e-03 2.7e-04 6.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail5.216.923.63.54.64.74.64.6-1.7-4.6-3.83.74.54.9-3.53.8
BMI without tail1.42.85.51.12.02.12.01.90.1-2.0-1.31.21.92.3-1.21.4
Body weight0.93.85.31.62.22.22.22.1-0.8-2.2-1.81.72.12.3-1.71.9
Epididymis fat weight0.30.61.2-1.0-0.8-0.6-0.8-0.71.10.81.0-1.0-0.8-0.5-0.1-0.1
Glucose1.01.52.21.11.31.41.41.4-0.5-1.4-1.11.11.51.4-0.91.1
Heart weight0.50.71.3-1.1-0.8-0.7-0.8-0.81.10.81.0-1.1-0.9-0.70.2-0.4
Left kidney weight0.00.10.60.4-0.0-0.2-0.0-0.0-0.7-0.0-0.30.3-0.1-0.3-0.30.2
Right kidney weight1.02.94.4-1.5-2.0-2.0-1.9-1.90.71.91.6-1.6-2.0-2.11.1-1.3
Tail length3.09.210.8-3.0-3.3-3.2-3.3-3.32.13.23.1-3.1-3.2-3.22.5-2.7
Length with tail1.45.28.1-1.9-2.6-2.7-2.5-2.60.82.52.1-2.0-2.5-2.81.7-1.9
Length without tail0.10.21.40.60.0-0.20.0-0.1-1.20.0-0.50.50.0-0.4-0.20.2
Liver weight, left2.03.24.51.31.92.01.91.9-0.3-1.9-1.41.41.82.1-2.12.1
Liver weight, right1.93.15.31.51.81.81.81.8-1.0-1.8-1.61.61.81.8-2.32.3
Parametrial fat weight0.50.91.1-1.0-1.0-1.0-1.0-1.00.81.11.0-1.0-1.0-1.00.8-0.8
Retroperitoneal fat weight0.30.91.50.61.01.10.91.0-0.0-1.0-0.70.60.91.2-1.21.2
Intraocular pressure0.40.63.0-1.2-0.4-0.3-0.5-0.61.70.51.1-1.1-0.5-0.00.1-0.1
Extensor digitorum longus weight3.212.919.32.73.94.23.94.1-0.7-4.1-3.02.94.14.4-3.33.6
Soleus weight7.421.528.14.35.25.35.25.2-2.4-5.2-4.54.55.25.3-3.33.7
Tibialis anterior weight0.93.24.41.71.92.02.02.1-1.1-2.1-1.81.72.12.0-1.31.4
Tibia length0.92.43.0-1.5-1.7-1.7-1.7-1.61.01.71.6-1.6-1.7-1.71.2-1.4
Number of licking bursts0.30.31.4-0.7-0.20.0-0.2-0.21.20.20.6-0.6-0.10.31.0-0.8
Food consumed during 24 hour testing period0.40.40.80.60.70.80.70.7-0.3-0.7-0.60.60.90.90.3-0.0
Times rat made contact with spout0.10.10.3-0.10.30.40.30.30.6-0.30.1-0.10.30.50.4-0.3
Mean time between licks in bursts4.46.16.9-2.4-2.6-2.5-2.6-2.61.82.62.5-2.5-2.6-2.52.4-2.5
Mean num. licks in bursts0.20.20.60.50.30.20.30.3-0.6-0.3-0.40.40.30.1-0.80.6
Std. dev. time between licks in bursts0.50.61.0-0.2-0.8-0.9-0.8-0.8-0.50.80.3-0.3-0.8-1.01.0-1.0
Water consumed over 24 hours0.91.11.91.31.00.91.01.0-1.4-1.0-1.31.31.00.8-0.50.6
Indifference point 0 sec0.20.30.40.60.50.50.50.5-0.5-0.5-0.60.60.50.50.6-0.4
Indifference point AUC0.91.01.4-1.1-1.2-1.1-1.2-1.10.91.11.2-1.2-1.0-1.10.2-0.4
Indifference point function ln k0.20.30.40.50.50.60.60.6-0.3-0.5-0.50.50.60.50.6-0.4
Indifference point function log k0.20.30.40.50.50.60.60.6-0.3-0.5-0.50.50.60.50.6-0.4
Delay discounting total patch changes 0 sec0.10.20.70.40.40.40.40.3-0.3-0.4-0.40.40.40.40.8-0.6
Delay discounting total patch changes 12 sec0.20.20.5-0.10.40.50.40.40.7-0.40.0-0.00.40.7-0.60.7
Delay discounting total patch changes 18 sec1.11.41.7-1.1-1.2-1.2-1.2-1.30.71.31.1-1.1-1.2-1.21.2-1.2
Delay discounting total patch changes 24 sec0.10.10.3-0.2-0.3-0.3-0.3-0.40.10.30.3-0.2-0.3-0.20.6-0.5
Delay discounting total patch changes 6 sec0.20.41.1-0.4-0.6-0.5-0.6-0.60.20.60.4-0.4-0.6-0.51.1-1.0
Delay discounting time to switch 0 sec2.23.44.22.01.91.71.81.7-1.9-1.8-2.02.01.61.5-2.01.9
Delay discounting water rate 0 sec0.40.62.3-1.1-0.7-0.4-0.6-0.41.50.61.0-1.0-0.3-0.10.8-0.7
Delay discounting water rate 12 sec0.30.51.5-0.10.71.00.80.81.0-0.8-0.10.00.81.2-0.10.3
Delay discounting water rate 18 sec1.41.97.4-1.9-1.0-0.6-1.0-0.82.71.01.8-1.8-0.8-0.21.3-1.1
Delay discounting water rate 24 sec0.60.85.5-1.3-0.20.3-0.1-0.02.40.11.1-1.10.10.6-0.50.5
Delay discounting water rate 6 sec1.11.64.0-1.7-1.1-0.9-1.1-1.02.01.11.6-1.6-1.0-0.71.2-1.2
Locomotor activity2.43.86.2-1.1-2.1-2.3-2.1-2.1-0.22.11.3-1.3-2.0-2.42.5-2.5
Locomotor testing distance1.62.74.6-1.1-1.7-1.9-1.7-1.70.11.81.2-1.2-1.7-1.92.2-2.1
Locomotor testing rearing0.20.31.1-0.5-0.3-0.3-0.3-0.40.60.30.4-0.4-0.4-0.21.0-0.9
Light reinforcement 14.48.111.2-2.5-3.1-3.3-3.1-3.21.23.12.7-2.6-3.2-3.42.4-2.6
Light reinforcement 21.41.82.9-1.2-1.5-1.6-1.5-1.60.51.51.2-1.2-1.5-1.70.8-1.0
Reaction time number correct0.20.30.8-0.20.50.70.50.50.9-0.50.0-0.10.60.90.3-0.1
Reaction time mean minus median0.60.81.2-0.8-1.1-1.1-1.1-0.90.41.00.9-0.8-1.0-1.00.3-0.4
Reaction time mean minus median AUC0.20.31.80.80.2-0.00.20.3-1.3-0.2-0.70.70.2-0.1-0.40.4
Reaction time num false alarms0.20.21.7-0.20.00.10.00.10.4-0.10.1-0.20.10.31.3-1.1
Reaction time num false alarms AUC0.20.31.7-0.30.10.20.10.10.8-0.10.3-0.30.20.41.3-1.0
Reaction time trials correct on left0.20.30.8-0.20.50.70.50.50.9-0.50.0-0.10.60.90.3-0.1
Reaction time trials on left0.20.30.9-0.10.50.70.50.60.8-0.5-0.0-0.00.60.90.3-0.1
Reaction time mean0.20.20.90.70.20.10.20.2-1.0-0.2-0.60.60.20.1-0.70.6
Reaction time mean AUC0.30.31.10.70.30.20.30.3-1.0-0.3-0.70.70.30.2-0.90.8
Median of all reaction times0.60.81.61.10.70.60.70.7-1.3-0.8-1.11.10.70.6-1.01.0
Reaction time omissions0.20.20.4-0.3-0.6-0.6-0.6-0.5-0.00.50.4-0.3-0.4-0.60.3-0.4
Reaction time false alarm rate0.10.10.60.10.10.10.10.1-0.1-0.1-0.10.10.10.10.8-0.7
Reaction time premature initiation rate1.52.02.4-1.5-1.4-1.3-1.4-1.41.41.41.5-1.5-1.5-1.21.3-1.4
Reaction time premature initiations1.42.03.9-1.7-1.3-1.0-1.2-1.22.01.31.6-1.7-1.3-0.81.5-1.5
Std. dev. reaction times0.10.20.3-0.1-0.5-0.6-0.5-0.4-0.20.50.2-0.2-0.5-0.5-0.50.3
Reaction time trials completed0.20.30.9-0.10.50.70.50.60.8-0.5-0.0-0.00.60.90.3-0.1
Reaction time trials AUC0.20.31.2-0.30.40.70.40.51.1-0.40.2-0.20.50.90.4-0.2
Social response proportion0.30.30.7-0.3-0.6-0.7-0.6-0.7-0.10.60.4-0.4-0.8-0.9-0.50.2
Social responses4.86.310.4-1.9-2.8-3.0-2.8-2.80.52.82.1-2.1-2.9-3.21.9-2.3
Social time0.60.71.50.60.90.90.90.8-0.2-0.9-0.60.60.80.9-1.21.2
Conditioned locomotion0.60.81.90.21.11.31.11.00.7-1.0-0.40.30.91.4-0.50.6
Cocaine response after cond. corrected2.93.36.31.12.02.32.02.10.3-2.1-1.31.22.02.5-1.61.8
Cocaine response after cond. not corrected3.13.56.61.02.12.32.12.10.4-2.1-1.31.22.02.6-1.82.0
Cocaine response before conditioning0.30.30.7-0.4-0.6-0.7-0.6-0.7-0.10.70.4-0.4-0.7-0.80.1-0.3
Saline control response0.00.00.1-0.10.20.20.20.10.3-0.10.0-0.00.20.30.1-0.0
Condit. Reinf. active minus inactive responses3.03.74.3-2.0-1.9-1.8-1.9-1.91.71.92.0-2.0-1.8-1.72.1-2.1
Condit. Reinf. active-inactive response ratio0.70.72.7-1.2-0.7-0.4-0.7-0.61.60.61.1-1.2-0.6-0.30.5-0.5
Condit. Reinf. active responses2.33.24.5-1.6-1.9-1.9-1.9-1.81.01.81.7-1.7-1.8-1.82.1-2.1
Condit. Reinf. inactive responses0.81.01.6-0.6-1.1-1.2-1.1-1.1-0.11.10.7-0.7-1.1-1.31.1-1.2
Condit. Reinf. lever presses2.63.64.0-2.0-2.0-1.9-2.0-2.01.62.02.0-2.0-2.0-1.91.7-1.8
Condit. Reinf. lever reinforcers received2.02.83.7-1.6-1.7-1.7-1.7-1.71.21.71.7-1.6-1.6-1.61.9-1.9
Pavlov. Cond. lever latency0.70.91.50.81.01.11.01.1-0.3-1.1-0.80.81.11.2-0.70.8
Pavlov. Cond. magazine entry latency0.30.40.7-0.4-0.7-0.8-0.7-0.7-0.00.70.5-0.4-0.7-0.80.4-0.5
Pavlov. Cond. change in total contacts0.71.01.5-1.0-1.1-1.1-1.1-1.10.61.11.0-1.0-1.1-1.20.8-0.9
Pavlov. Cond. index score0.81.01.6-0.9-1.1-1.2-1.1-1.10.41.10.9-0.9-1.2-1.30.8-1.0
Pavlov. Cond. latency score0.60.81.4-0.7-1.0-1.1-1.0-1.00.21.00.8-0.7-1.1-1.20.7-0.9
Pavlov. Cond. lever contacts0.81.11.4-1.0-1.1-1.1-1.1-1.10.71.11.1-1.0-1.2-1.20.7-0.9
Pavlov. Cond. magazine entry number0.50.71.20.51.01.01.00.9-0.0-0.9-0.60.60.91.1-0.70.8
Pavlov. Cond. intertrial magazine entries0.10.20.7-0.00.40.60.40.40.5-0.4-0.10.10.40.8-0.10.2
Pavlov. Cond. lever-magazine prob. diff.0.71.01.6-0.8-1.1-1.1-1.1-1.10.31.10.9-0.8-1.1-1.30.8-1.0
Pavlov. Cond. response bias1.82.53.1-1.5-1.7-1.7-1.7-1.71.11.71.6-1.6-1.7-1.81.3-1.5
Conditioned reinforcement - actives2.32.23.0-1.3-1.7-1.7-1.7-1.60.81.71.4-1.4-1.5-1.71.3-1.4
Conditioned reinforcement - inactives0.30.30.60.10.60.70.60.60.4-0.5-0.20.20.60.7-0.80.8
Conditioned locomotion6.88.110.5-2.6-3.2-3.2-3.2-3.01.63.22.8-2.8-2.9-3.22.3-2.5
Intermittent access intake day 1-15 change6.96.98.0-2.5-2.8-2.8-2.8-2.81.72.82.6-2.6-2.7-2.72.4-2.6
Intermittent access intake escalation8.07.99.3-3.0-2.9-2.8-2.9-2.82.52.93.0-3.0-2.8-2.62.4-2.6
Intermittent access intake escalation 29.49.310.8-3.3-3.2-3.0-3.2-3.12.73.13.3-3.3-3.2-2.92.5-2.7
Intermitt. access day 1 inactive lever presses0.60.61.2-1.0-0.9-0.7-0.9-0.61.10.91.0-1.0-0.5-0.50.5-0.4
Intermitt. access day 15 inactive lever presses0.60.60.8-0.9-0.8-0.8-0.8-0.80.80.80.9-0.9-0.8-0.70.5-0.6
Intermitt. access escalation Index0.70.61.81.10.70.50.70.5-1.4-0.6-1.01.00.80.40.30.0
Intermittent access day 1 total infusions0.10.10.10.30.30.30.30.3-0.3-0.2-0.30.30.20.2-0.40.3
Intermittent access day 15 total infusions2.22.52.9-1.7-1.7-1.6-1.7-1.61.41.71.7-1.7-1.6-1.51.2-1.4
Intermittent access terminal intake (last 3 days)1.21.31.6-1.1-1.2-1.2-1.2-1.20.81.31.1-1.1-1.2-1.20.9-1.0
Intermittent access total infusions0.30.30.4-0.6-0.6-0.5-0.6-0.50.60.60.6-0.6-0.5-0.50.3-0.4
Intermittent access day 1 locomotion0.40.40.5-0.7-0.6-0.6-0.6-0.60.50.70.7-0.7-0.7-0.60.2-0.4
Intermittent access day 15 total locomotion3.53.74.6-1.9-2.2-2.1-2.2-2.01.42.12.0-2.0-2.1-2.11.2-1.5
Intermittent access total locomotion0.91.01.4-1.0-1.2-1.2-1.2-1.00.61.21.0-1.0-1.0-1.20.5-0.7
Intermittent access standard deviation3.23.44.3-1.9-2.1-2.0-2.1-1.81.52.02.0-2.0-1.9-1.90.9-1.3
Cocaine induced anxiety0.30.30.9-0.0-0.6-0.8-0.6-0.6-0.60.60.2-0.1-0.7-0.90.1-0.2
Post-drug Anxiety0.20.21.00.4-0.3-0.5-0.3-0.3-1.00.3-0.20.3-0.7-0.7-0.70.3
Baseline Anxiety0.20.20.5-0.5-0.3-0.2-0.3-0.30.70.30.5-0.5-0.6-0.10.1-0.3
Lifetime Intake0.10.10.1-0.3-0.3-0.3-0.3-0.30.30.40.3-0.3-0.3-0.30.1-0.1
Incentive Sensitization - Responses0.50.50.9-0.8-0.8-0.6-0.8-0.50.90.70.9-0.9-0.4-0.50.4-0.4
Incentive Sensitization - Breakpoint0.50.50.7-0.8-0.8-0.7-0.8-0.60.80.80.8-0.8-0.5-0.50.4-0.4
Progressive ratio test 1 active lever presses0.00.00.1-0.10.20.30.20.20.3-0.1-0.0-0.00.20.3-0.30.3
Progressive ratio test 1 breakpoint0.10.10.20.10.30.40.30.30.2-0.3-0.20.10.30.4-0.40.4
Progressive ratio test 1 inactive lever presses0.00.00.0-0.0-0.1-0.1-0.1-0.1-0.00.10.0-0.00.0-0.1-0.10.1
Progressive ratio test 2 active lever presses0.40.40.7-0.8-0.7-0.6-0.7-0.50.80.70.8-0.8-0.5-0.50.2-0.3
Progressive ratio test 2 breakpoint0.30.30.5-0.6-0.7-0.6-0.7-0.50.40.70.6-0.6-0.5-0.60.2-0.4
Progressive ratio test 2 inactive lever presses0.00.00.1-0.1-0.2-0.3-0.2-0.1-0.00.30.1-0.1-0.1-0.2-0.20.1
Total sessions with >9 infusions0.10.10.40.40.1-0.00.10.1-0.6-0.0-0.30.30.3-0.10.10.1
Short access day 1 total inactive lever presses0.00.00.1-0.3-0.2-0.2-0.2-0.30.20.20.3-0.3-0.0-0.20.10.0
Short access day 10 total inactive lever presses0.20.20.5-0.6-0.4-0.3-0.4-0.30.70.40.6-0.6-0.1-0.2-0.10.1
Short access day 1 total infusions0.10.10.40.2-0.1-0.3-0.1-0.2-0.60.1-0.10.2-0.1-0.40.1-0.1
Short access day 10 total infusions0.00.00.1-0.2-0.2-0.2-0.2-0.10.30.30.2-0.3-0.1-0.10.0-0.1
Short access total infusions0.00.00.10.20.0-0.00.00.1-0.20.1-0.10.10.1-0.0-0.10.1
Short access day 1 locomotion0.60.61.3-0.5-0.9-1.0-0.9-0.9-0.20.90.5-0.5-0.8-1.10.8-0.8
Short access day 10 total locomotion4.54.95.9-2.2-2.4-2.3-2.4-2.31.62.42.3-2.3-2.0-2.32.0-1.9
Short access total locomotion0.80.81.3-0.7-1.0-1.1-1.0-1.00.31.10.8-0.8-0.8-1.10.9-0.9
Compulsive drug intake1.31.31.81.21.21.11.21.2-1.1-1.1-1.21.21.31.1-0.91.1
One hour access (0.3 mA shock)0.20.20.50.30.40.40.40.5-0.2-0.4-0.40.30.40.5-0.70.6
One hour access (shock baseline)0.20.20.5-0.6-0.4-0.3-0.4-0.30.70.40.6-0.6-0.4-0.20.1-0.2
Number of responses in last shaping day0.10.10.2-0.3-0.4-0.5-0.4-0.30.10.50.3-0.3-0.2-0.40.4-0.3
Context. condit. distance diff. score0.20.20.40.40.50.60.60.6-0.1-0.6-0.40.40.60.6-0.10.3
Locomotion velocity, session 10.30.30.80.2-0.5-0.6-0.4-0.4-0.90.4-0.10.1-0.5-0.9-0.80.5
Locomotion distance, session 10.40.62.40.90.1-0.10.20.2-1.5-0.2-0.80.80.2-0.3-1.31.1
Locomotion velocity, session 21.41.74.2-0.5-1.6-1.8-1.5-1.5-0.81.50.7-0.6-1.6-2.1-0.60.1
Locomotion distance, session 20.50.71.90.1-1.0-1.2-0.9-0.9-1.10.90.1-0.1-1.0-1.4-0.60.3
Locomotion velocity, session 35.46.27.7-2.3-2.7-2.8-2.7-2.71.42.72.4-2.4-2.8-2.82.1-2.4
Locomotion distance, session 30.00.00.1-0.1-0.1-0.0-0.0-0.00.20.00.1-0.10.0-0.1-0.30.3
Stereotopy head waving bouts, day 33.54.26.0-1.6-2.2-2.4-2.2-2.20.52.21.7-1.7-2.3-2.42.1-2.2
Stereotopy head waving duration, day 34.35.37.1-1.9-2.5-2.6-2.5-2.50.82.52.0-2.0-2.6-2.72.1-2.4
Locomotion velocity, session 70.50.50.9-0.5-0.8-0.9-0.8-0.80.00.80.6-0.5-0.8-0.90.5-0.6
Locomotion distance, session 70.10.10.4-0.30.10.20.10.10.6-0.10.2-0.30.10.2-0.50.4
Stereotopy head waving bouts, day 70.30.31.70.80.30.10.30.3-1.3-0.3-0.70.80.2-0.0-0.10.1
Stereotopy head waving duration, day 70.20.21.60.6-0.1-0.3-0.1-0.1-1.20.1-0.50.5-0.1-0.40.4-0.4
Locomotion velocity, session 80.30.32.00.6-0.3-0.5-0.3-0.3-1.40.3-0.40.5-0.4-0.7-0.40.2
Locomotion distance, session 80.00.00.20.1-0.2-0.3-0.2-0.2-0.40.2-0.10.1-0.2-0.3-0.30.2
Degree of sensitization distance0.30.30.40.50.60.60.60.6-0.3-0.6-0.60.60.60.6-0.60.6
Degree of sensitization stereotypy2.42.63.41.81.61.51.61.6-1.7-1.6-1.81.81.71.4-1.31.4
Condit. Reinf. active minus inactive responses3.33.64.9-1.7-2.2-2.2-2.1-2.10.92.11.8-1.8-2.2-2.21.4-1.6
Condit. Reinf. active-inactive response ratio2.22.42.8-1.6-1.7-1.6-1.6-1.61.31.61.7-1.7-1.7-1.50.9-1.1
Condit. Reinf. active responses2.22.64.3-1.1-1.9-2.0-1.9-1.90.11.91.3-1.3-1.9-2.11.2-1.4
Condit. Reinf. inactive responses0.30.40.90.1-0.7-0.8-0.6-0.6-0.80.60.1-0.1-0.6-0.90.4-0.5
Incentive salience index mean1.21.52.6-0.8-1.5-1.6-1.4-1.4-0.11.40.9-0.9-1.4-1.60.9-1.1
Condit. Reinf. lever presses0.40.53.21.10.20.10.40.4-1.8-0.4-1.01.00.3-0.1-0.20.2
Time in familiar zone, hab. session 12.52.43.5-1.5-1.5-1.5-1.6-1.61.11.61.5-1.5-1.7-1.41.8-1.9
Time in novel zone, hab. session 11.81.72.51.51.11.11.21.2-1.6-1.2-1.51.51.30.9-1.41.5
Total zone transitions, hab. session 10.30.41.20.0-0.8-0.9-0.7-0.7-0.80.70.1-0.1-0.8-1.1-0.40.1
Total locomotion distance, hab. session 10.40.62.60.5-0.6-0.9-0.6-0.6-1.60.6-0.30.3-0.7-1.2-0.60.2
Locomotion velocity, hab. session 10.50.82.10.0-1.0-1.2-1.0-1.0-1.11.00.2-0.1-1.1-1.4-0.40.1
Time in familiar zone, hab. session 26.87.17.9-2.8-2.7-2.7-2.8-2.82.22.82.8-2.8-2.8-2.62.4-2.6
Time in novel zone, hab. session 25.35.46.42.52.42.32.42.4-2.2-2.4-2.52.52.42.2-1.92.0
Total zone transitions, hab. session 21.41.85.31.50.80.60.80.8-1.9-0.8-1.41.40.80.4-2.32.1
Total locomotion distance, hab. session 20.30.41.1-0.0-0.7-0.9-0.7-0.7-0.70.70.1-0.1-0.8-1.0-0.80.4
Locomotion velocity, hab. session 20.40.51.40.2-0.6-0.8-0.6-0.6-1.10.6-0.10.1-0.7-1.0-1.20.8
Novel to familiar place preference ratio5.25.46.62.62.32.22.32.3-2.4-2.3-2.62.62.42.0-2.12.2
Novelty place preference3.53.64.52.11.81.71.91.9-2.0-1.9-2.12.11.91.5-1.91.9
Time in novel zone, NPP test3.73.94.72.21.91.82.02.0-2.0-2.0-2.12.22.01.6-2.02.0
Total zone transitions, NPP test0.50.73.90.70.30.20.30.3-0.9-0.3-0.60.60.20.1-2.01.7
Total locomotion distance, NPP test0.70.93.61.00.50.30.50.5-1.3-0.5-0.90.90.40.2-1.91.6
Locomotion velocity, NPP test0.40.63.00.70.20.00.20.2-1.1-0.2-0.60.60.1-0.1-1.71.4
Pavlov. Cond. lever latency0.30.31.6-0.9-0.4-0.2-0.4-0.41.30.40.8-0.8-0.3-0.10.1-0.0
Pavlov. Cond. magazine entry latency2.73.54.2-1.8-2.0-2.0-2.0-2.01.32.01.9-1.9-2.0-1.91.7-1.8
Pavlov. Cond. change in total contacts0.10.10.2-0.1-0.2-0.2-0.2-0.2-0.00.20.1-0.1-0.2-0.20.5-0.5
Pavlov. Cond. index score0.20.20.4-0.1-0.5-0.6-0.5-0.5-0.40.50.2-0.1-0.6-0.70.6-0.7
Pavlov. Cond. latency score0.20.20.60.2-0.4-0.5-0.4-0.4-0.80.4-0.10.1-0.5-0.60.5-0.6
Pavlov. Cond. lever contacts0.30.31.90.80.2-0.00.20.2-1.4-0.2-0.70.70.1-0.20.1-0.1
Pavlov. Cond. magazine entry number0.60.70.90.70.90.90.90.9-0.4-0.9-0.80.81.00.9-0.90.9
Pavlov. Cond. intertrial magazine entries0.40.51.3-0.9-0.6-0.4-0.6-0.61.10.60.8-0.9-0.5-0.30.6-0.5
Pavlov. Cond. lever-magazine prob. diff.0.40.50.9-0.3-0.8-0.9-0.8-0.8-0.20.80.4-0.4-0.9-0.90.9-0.9
Pavlov. Cond. response bias0.81.01.4-0.9-1.1-1.1-1.1-1.10.51.10.9-0.9-1.2-1.10.8-0.9
Bone: apparent density0.71.26.21.70.60.30.60.6-2.5-0.6-1.51.50.70.00.6-0.5
Bone surface1.01.811.01.90.3-0.20.30.3-3.3-0.3-1.61.70.4-0.51.3-1.0
Bone volume1.11.810.91.90.3-0.20.30.3-3.3-0.3-1.61.70.3-0.61.3-1.1
Bone: connectivity density0.91.44.71.71.00.71.01.0-2.2-1.0-1.51.61.00.50.00.1
Bone: cortical apparent density0.60.81.30.81.01.01.01.0-0.4-1.0-0.90.81.01.1-0.30.5
Bone: cortical area0.91.43.21.61.11.01.11.1-1.8-1.1-1.51.51.10.8-0.20.3
Bone: cortical porosity0.30.30.7-0.2-0.6-0.7-0.6-0.6-0.30.60.3-0.3-0.6-0.90.4-0.5
Bone: cortical porosity0.20.21.10.60.1-0.00.10.1-1.1-0.1-0.50.60.1-0.2-0.10.1
Bone: cortical thickness1.21.92.41.51.51.41.51.5-1.3-1.5-1.51.51.41.4-0.81.0
Bone: cortical thickness0.10.20.7-0.6-0.3-0.1-0.3-0.30.80.30.5-0.5-0.3-0.00.0-0.0
Bone: cortical tissue density0.40.50.90.60.80.90.80.8-0.3-0.8-0.70.70.80.9-0.20.4
Bone: elastic displacement0.20.20.4-0.3-0.5-0.6-0.5-0.50.10.50.4-0.4-0.5-0.60.4-0.5
Bone: elastic work0.30.40.70.80.60.50.60.6-0.9-0.6-0.80.80.60.40.10.0
Bone: endosteal estimation0.30.61.21.00.80.70.80.8-1.1-0.8-1.01.00.80.70.10.1
Bone: endosteal perimeter0.20.31.00.2-0.4-0.6-0.4-0.4-0.90.4-0.10.1-0.4-0.71.0-1.0
Bone: final force1.52.53.61.91.61.51.61.6-1.8-1.6-1.91.91.61.4-0.80.9
Bone: final moment1.22.03.01.71.41.31.41.4-1.7-1.4-1.71.71.41.2-0.70.8
Bone: marrow area0.30.61.11.00.80.70.80.8-1.1-0.8-1.01.00.80.70.10.1
Bone: maximum diameter0.40.71.20.0-0.8-1.0-0.8-0.8-0.90.80.1-0.1-0.8-1.11.1-1.1
Bone: maximum force1.42.43.21.81.61.51.61.6-1.6-1.6-1.81.81.61.5-0.81.0
Bone: maximum moment1.12.02.81.71.51.41.51.5-1.5-1.5-1.61.71.41.3-0.70.9
Bone: minimum diameter0.20.31.10.70.30.10.30.3-1.0-0.3-0.60.70.30.10.8-0.6
Bone: periosteal estimation0.71.43.51.61.10.91.11.1-1.9-1.1-1.51.51.10.80.00.1
Bone: periosteal perimeter0.20.31.90.70.0-0.20.00.0-1.4-0.0-0.60.60.0-0.30.7-0.6
Bone: post-yield work0.50.61.00.70.80.90.80.8-0.3-0.8-0.70.70.81.0-0.70.8
Bone: stiffness3.04.75.52.32.32.32.32.3-1.8-2.3-2.32.32.32.3-1.21.4
Bone: tissue strength1.71.71.91.31.41.31.41.4-0.9-1.4-1.31.31.31.4-1.21.2
Bone: trabecular number0.30.41.50.3-0.6-0.8-0.6-0.6-1.20.6-0.10.2-0.6-1.10.5-0.6
Bone: trabecular spacing0.50.64.2-1.00.10.50.10.12.1-0.10.8-0.80.10.8-0.20.3
Bone: trabecular thickness1.62.010.42.10.70.20.70.7-3.2-0.7-1.81.90.8-0.20.9-0.7
Bone: trabecular tissue density1.01.43.00.61.41.61.41.40.3-1.4-0.80.81.31.7-0.81.0
Breakpoint value in progressive ratio session6.06.77.7-2.6-2.6-2.6-2.7-2.72.02.72.6-2.6-2.6-2.52.8-2.8
Distance traveled before self-admin0.50.61.20.80.50.60.60.8-0.7-0.6-0.70.70.90.6-1.11.1
Distance traveled after self-admin0.50.51.0-0.6-1.0-0.9-0.9-0.80.10.80.6-0.6-0.7-1.00.3-0.4
Delta time in closed arm before/after self-admin0.40.42.8-0.70.30.60.30.31.7-0.30.5-0.60.40.80.00.2
Delta time in open arm before/after self-admin1.61.52.51.21.21.21.21.2-1.0-1.2-1.21.21.11.1-1.61.4
Diff in mean of infusions in LGA sessions1.61.82.2-1.2-1.4-1.4-1.4-1.50.81.31.3-1.3-1.4-1.41.4-1.4
Extinction: sum of active levers before priming2.12.13.1-1.7-1.4-1.3-1.4-1.31.81.51.7-1.7-1.2-1.11.2-1.2
Active lever presses in extinction session 62.52.43.3-1.4-1.8-1.8-1.8-1.70.71.71.5-1.5-1.6-1.81.3-1.4
Delta distance traveled before/after self-admin1.41.52.2-1.1-1.3-1.4-1.3-1.40.51.21.1-1.1-1.5-1.41.3-1.3
Delta ambulatory time before/after self-admin1.31.42.1-0.9-1.3-1.4-1.3-1.40.31.21.0-1.0-1.4-1.41.1-1.2
Time in closed arm before self-admin1.51.82.71.51.31.11.21.1-1.6-1.2-1.51.51.20.9-1.51.5
Time in closed arm after self-admin0.00.00.1-0.2-0.1-0.1-0.0-0.20.30.10.2-0.2-0.1-0.00.4-0.2
Time in open arm before self-admin1.31.42.9-1.1-1.2-1.1-1.2-1.00.91.21.2-1.2-0.9-1.11.7-1.5
Time in open arm after self-admin0.50.60.90.60.80.90.70.9-0.3-0.8-0.70.70.90.8-0.60.6
Sum of active levers in priming session hrs 5-60.00.00.2-0.1-0.1-0.0-0.1-0.00.20.10.1-0.10.0-0.0-0.50.4
Time to tail flick, vehicle, before self-admin0.20.20.70.2-0.4-0.6-0.5-0.3-0.80.4-0.10.1-0.4-0.7-0.20.0
Time to tail flick, vehicle, after self-admin0.50.61.6-0.9-0.4-0.3-0.4-0.61.30.50.8-0.9-0.6-0.21.0-0.9
Time to tail flick, test, before self-admin0.10.10.70.4-0.0-0.3-0.2-0.3-0.90.2-0.30.3-0.2-0.40.1-0.1
Time to tail flick, test, after self-admin0.10.10.20.1-0.3-0.4-0.3-0.3-0.40.3-0.00.0-0.3-0.4-0.1-0.0
Delta time to tail flick, vehicle, before/after SA0.30.31.5-0.50.40.50.40.21.2-0.30.3-0.40.20.70.7-0.5
Delta time to tail flick, test, before/after SA0.30.30.8-0.8-0.5-0.4-0.5-0.40.90.40.7-0.7-0.5-0.30.0-0.1
Ambulatory time before self-admin0.40.40.90.60.40.50.50.7-0.5-0.5-0.60.60.80.5-0.90.9
Ambulatory time after self-admin0.30.30.6-0.4-0.8-0.7-0.7-0.50.10.60.5-0.5-0.5-0.7-0.1-0.0
Total heroin consumption1.82.13.0-1.2-1.5-1.6-1.6-1.50.61.61.3-1.3-1.5-1.51.7-1.7
Area under the delay curve2.22.43.31.71.61.61.61.8-1.3-1.6-1.71.71.61.6-0.81.0
Delay disc. indifference point, 0s delay9.610.412.33.43.13.03.23.1-3.1-3.2-3.43.43.22.8-3.43.5
Delay disc. indifference point, 16s delay0.20.20.30.50.40.40.40.6-0.4-0.4-0.50.50.40.40.5-0.4
Delay disc. indifference point, 2s delay6.47.27.72.72.72.72.82.7-2.2-2.8-2.82.82.82.6-2.62.8
Delay disc. indifference point, 24s delay0.50.51.00.60.80.80.71.0-0.3-0.7-0.60.60.70.70.7-0.5
Delay disc. indifference point, 4s delay1.51.62.51.61.31.21.21.4-1.6-1.2-1.51.61.21.10.3-0.0
Delay disc. indifference point, 8s delay0.80.81.30.71.01.11.01.1-0.2-1.0-0.80.71.01.1-0.91.0
Delay discount exponential model param1.92.03.0-1.5-1.5-1.5-1.5-1.71.21.51.6-1.6-1.5-1.50.6-0.8
Delay discount hyperbolic model param2.82.93.9-1.8-1.9-1.8-1.8-2.01.41.81.9-1.9-1.8-1.80.9-1.1
Fecal boli incidents, locomotor time 11.82.07.10.61.21.31.21.10.2-1.2-0.70.71.21.4-2.72.5
Change in fecal boli incidents, locomotor task0.30.30.80.3-0.3-0.5-0.3-0.4-0.90.3-0.20.2-0.3-0.50.9-0.8
Time >=10cm from walls, locomotor time 10.60.61.31.00.60.60.70.7-1.1-0.7-1.01.00.70.4-0.90.8
Bouts of movement, locomotor time 10.20.20.3-0.5-0.5-0.5-0.5-0.50.40.50.5-0.5-0.5-0.4-0.20.0
Total resting periods, locomotor time 10.20.20.3-0.4-0.6-0.5-0.5-0.50.20.50.5-0.5-0.5-0.50.0-0.2
Rest time, locomotor task time 10.10.10.3-0.2-0.5-0.4-0.4-0.5-0.00.40.3-0.2-0.3-0.5-0.10.1
Distance moved, locomotor task time 10.80.82.01.20.90.70.80.9-1.4-0.8-1.21.20.80.60.2-0.0
Vertical activity count, locomotor time 10.10.10.40.00.20.20.20.10.1-0.2-0.10.10.20.30.6-0.5
Time >=10cm from walls, locomotor time 20.70.71.10.50.81.00.91.00.0-0.9-0.60.61.01.1-1.01.0
Bouts of movement, locomotor time 20.20.20.50.2-0.4-0.5-0.4-0.3-0.70.4-0.10.1-0.3-0.7-0.20.1
Total resting periods, locomotor time 20.10.20.70.3-0.4-0.5-0.3-0.2-0.80.3-0.10.2-0.3-0.70.0-0.2
Rest time, locomotor task time 20.30.40.8-0.2-0.7-0.7-0.6-0.5-0.30.60.3-0.3-0.7-0.90.8-0.9
Distance moved, locomotor task time 20.40.50.90.30.80.90.80.80.2-0.8-0.40.40.81.0-0.60.7
Vertical activity count, locomotor time 20.40.40.9-0.10.50.80.60.50.8-0.6-0.10.00.70.9-0.91.0
Weight adjusted by age0.10.10.6-0.20.40.50.30.30.8-0.20.1-0.10.30.50.2-0.1
Seeking ratio, delayed vs. immediate footshock3.54.06.1-1.5-2.2-2.4-2.2-2.20.52.21.7-1.7-2.2-2.51.9-2.1
Locomotion in novel chamber0.50.61.1-1.0-0.8-0.7-0.8-0.71.00.81.0-1.0-0.7-0.60.6-0.6
Locomotion in novel chamber post-restriction1.31.65.8-0.9-1.0-1.0-1.0-1.20.61.00.9-0.9-1.0-1.02.4-2.2
Progressive ratio0.50.63.50.00.40.50.40.40.4-0.4-0.10.00.30.5-1.91.5
Food seeking constrained by brief footshock0.10.10.5-0.3-0.3-0.3-0.3-0.40.20.30.3-0.3-0.3-0.2-0.70.6
Seeking ratio, punishment vs. effort0.10.20.6-0.1-0.3-0.4-0.3-0.5-0.20.30.1-0.1-0.2-0.40.8-0.6
Run reversals in cocaine runway, females0.30.30.6-0.1-0.5-0.6-0.5-0.4-0.30.50.2-0.2-0.5-0.60.8-0.8
Run reversals in cocaine runway, males0.80.81.2-0.5-1.0-1.1-0.9-1.10.01.00.6-0.6-1.0-1.01.1-1.1
Latency to leave start box in cocaine runway0.70.82.0-0.0-0.9-1.0-0.9-0.5-0.80.80.2-0.1-0.7-1.11.4-1.4
Latency to leave start box in cocaine runway, F0.50.63.21.20.20.10.20.5-1.8-0.2-1.01.00.5-0.0-0.50.4
Latency to leave start box in cocaine runway, M4.24.16.1-2.1-1.9-1.8-2.0-1.71.91.92.1-2.1-1.9-1.72.5-2.5
Cd content in liver0.30.30.80.50.50.50.50.5-0.4-0.5-0.50.50.40.4-0.90.8
Co content in liver0.60.70.9-1.0-0.9-0.9-0.9-0.70.80.91.0-1.0-0.8-0.90.7-0.8
Cu content in liver0.60.82.11.00.50.40.50.7-1.3-0.6-0.90.90.50.2-1.41.2
Fe content in liver0.10.20.5-0.5-0.2-0.2-0.2-0.30.70.30.5-0.5-0.2-0.1-0.60.5
K content in liver0.30.31.20.70.20.10.20.5-1.1-0.3-0.60.60.3-0.0-0.40.4
Mg content in liver0.30.41.70.90.20.10.30.6-1.3-0.4-0.70.80.4-0.0-0.50.4
Mn content in liver0.50.53.30.7-0.5-0.8-0.5-0.4-1.80.4-0.50.5-0.4-1.1-0.1-0.1
Na content in liver1.71.82.61.41.21.11.21.1-1.3-1.3-1.41.41.31.0-1.61.6
Rb content in liver0.91.22.71.40.90.80.91.0-1.6-0.9-1.31.31.00.6-0.91.0
Se content in liver0.10.10.2-0.2-0.4-0.4-0.4-0.30.00.40.3-0.3-0.2-0.4-0.20.1
Sr content in liver0.30.31.3-0.8-0.3-0.1-0.3-0.61.10.30.7-0.7-0.2-0.00.4-0.3
Zn content in liver3.33.66.0-2.3-1.9-1.6-1.9-1.72.51.82.3-2.3-1.6-1.41.4-1.5