Hub : Genes

Zdhhc24

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000019825 0.2 0.1 1.2e-09 0.17 0.16 0.16 0.16 1.5e-09 9.7e-09 8.1e-09 3.5e-09
2 BLA mRNA stability ENSRNOG00000019825 0.07 0.05 2.2e-03 0.02 0.05 0.04 0.03 3.5e-02 1.4e-03 4.0e-03 6.4e-03
3 Brain gene expression ENSRNOG00000019825 0.17 0.08 1.1e-15 0.16 0.16 0.15 0.16 1.0e-14 1.6e-14 9.8e-14 1.1e-14
4 Brain mRNA stability ENSRNOG00000019825 0.08 0.05 8.8e-07 0.04 0.07 0.06 0.06 3.0e-04 6.8e-07 3.6e-06 1.4e-06
5 LHb gene expression ENSRNOG00000019825 0.19 0.13 4.5e-03 0.1 0.02 0.05 -0.01 2.4e-03 1.3e-01 2.9e-02 7.9e-01
6 Liver gene expression ENSRNOG00000019825 0.12 0.07 5.4e-07 0.04 0.04 0.04 0.04 8.9e-06 8.8e-06 3.1e-05 3.8e-05
7 NAcc gene expression ENSRNOG00000019825 0.11 0.07 1.3e-06 0.06 0.08 0.07 0.07 3.3e-05 2.1e-06 7.6e-06 5.4e-06
8 PL gene expression ENSRNOG00000019825 0.11 0.07 1.9e-07 0.09 0.09 0.07 0.1 4.6e-07 4.1e-07 7.8e-06 1.1e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail1.65.116.2-0.8-2.9-0.7-3.3-1.0-4.00.4-1.7
BMI without tail0.51.13.2-0.4-1.4-0.2-1.6-0.3-1.80.4-0.6
Body weight1.14.514.52.0-0.22.0-0.71.9-3.82.91.2
Epididymis fat weight1.84.16.8-2.4-1.1-2.4-0.8-2.31.9-2.6-1.9
Glucose2.94.45.8-2.3-2.0-2.4-1.8-2.30.5-2.4-2.3
Heart weight1.72.44.0-1.8-0.9-1.8-0.7-1.81.6-2.0-1.3
Left kidney weight0.20.62.2-0.50.6-0.40.8-0.51.5-0.80.1
Right kidney weight0.20.51.80.11.00.31.30.10.8-0.20.6
Tail length2.06.17.72.72.62.72.42.80.42.62.7
Length with tail2.28.012.33.32.23.21.93.3-1.53.53.0
Length without tail1.32.85.01.90.71.70.51.9-2.12.21.4
Liver weight, left0.10.10.50.00.4-0.10.4-0.00.70.10.4
Liver weight, right0.10.10.50.10.30.30.30.30.70.20.3
Parametrial fat weight2.44.77.6-2.8-1.6-2.7-1.4-2.61.3-2.5-1.9
Retroperitoneal fat weight2.99.616.7-3.5-1.6-3.7-1.0-3.63.2-4.1-2.8
Intraocular pressure0.40.51.5-0.30.8-0.21.1-0.21.2-0.50.6
Extensor digitorum longus weight3.112.423.83.81.23.80.53.8-4.64.93.0
Soleus weight1.23.613.2-1.60.2-1.60.6-1.63.6-2.5-1.1
Tibialis anterior weight6.522.539.25.33.05.32.45.3-4.26.34.7
Tibia length0.71.92.41.41.21.51.31.5-1.31.51.4
Number of licking bursts0.10.10.60.3-0.20.1-0.20.1-0.80.20.0
Food consumed during 24 hour testing period0.10.10.40.30.50.20.60.2-0.00.20.6
Times rat made contact with spout0.20.20.80.2-0.50.1-0.70.1-0.90.3-0.2
Mean time between licks in bursts0.40.61.11.10.51.00.31.0-0.11.00.6
Mean num. licks in bursts0.10.20.2-0.4-0.4-0.4-0.4-0.40.4-0.4-0.5
Std. dev. time between licks in bursts1.01.21.71.01.21.01.11.01.30.91.2
Water consumed over 24 hours0.20.30.90.5-0.10.4-0.20.4-1.00.70.4
Indifference point 0 sec0.20.40.6-0.7-0.6-0.8-0.5-0.8-0.2-0.6-0.6
Indifference point AUC1.51.73.41.30.51.40.31.3-1.81.81.3
Indifference point function ln k2.43.312.7-1.50.0-1.50.4-1.53.6-2.4-1.2
Indifference point function log k2.43.312.7-1.50.0-1.50.4-1.53.6-2.4-1.2
Delay discounting total patch changes 0 sec0.00.00.0-0.10.1-0.20.1-0.20.2-0.10.0
Delay discounting total patch changes 12 sec1.31.76.51.1-0.11.0-0.41.0-2.51.80.9
Delay discounting total patch changes 18 sec0.20.31.4-0.2-0.5-0.2-0.6-0.1-1.20.30.1
Delay discounting total patch changes 24 sec1.31.63.01.40.71.40.51.3-1.31.71.3
Delay discounting total patch changes 6 sec0.30.52.70.3-0.50.2-0.70.2-1.60.70.0
Delay discounting time to switch 0 sec1.21.87.0-0.4-1.6-0.4-1.8-0.2-2.60.2-0.9
Delay discounting water rate 0 sec1.52.311.0-0.11.6-0.22.0-0.33.3-1.00.5
Delay discounting water rate 12 sec2.63.921.9-0.41.6-0.41.9-0.54.7-1.50.3
Delay discounting water rate 18 sec0.81.16.2-0.30.6-0.50.7-0.52.5-1.0-0.3
Delay discounting water rate 24 sec1.52.010.7-0.11.3-0.21.6-0.33.3-0.90.3
Delay discounting water rate 6 sec1.42.110.60.41.50.21.70.23.3-0.50.7
Locomotor activity0.71.15.20.31.10.31.30.22.3-0.30.5
Locomotor testing distance0.81.47.50.31.20.31.20.22.7-0.40.4
Locomotor testing rearing0.61.03.3-1.0-0.3-0.8-0.2-0.91.8-1.2-0.7
Light reinforcement 10.00.10.5-0.20.1-0.10.2-0.20.7-0.30.0
Light reinforcement 20.30.41.3-0.4-0.0-0.80.3-0.70.7-1.1-0.6
Reaction time number correct0.81.11.71.31.11.01.01.1-0.01.11.2
Reaction time mean minus median0.91.15.20.7-0.10.9-0.20.9-2.31.20.5
Reaction time mean minus median AUC1.01.32.11.20.71.30.61.4-1.21.51.1
Reaction time num false alarms0.91.21.81.11.21.11.21.01.40.81.1
Reaction time num false alarms AUC1.21.72.41.51.31.51.11.40.71.31.4
Reaction time trials correct on left0.81.11.71.31.11.01.01.1-0.01.11.2
Reaction time trials on left1.01.42.11.41.21.21.21.2-0.11.21.4
Reaction time mean0.00.00.1-0.2-0.1-0.1-0.10.0-0.3-0.2-0.2
Reaction time mean AUC0.10.10.2-0.4-0.3-0.3-0.2-0.2-0.4-0.3-0.4
Median of all reaction times0.10.20.3-0.5-0.3-0.5-0.2-0.30.0-0.6-0.5
Reaction time omissions0.91.32.11.30.61.30.41.3-1.11.41.1
Reaction time false alarm rate0.40.50.90.70.70.80.60.60.90.50.7
Reaction time premature initiation rate1.82.44.01.91.01.90.71.9-0.92.01.4
Reaction time premature initiations3.55.07.72.81.72.71.42.7-1.02.82.2
Std. dev. reaction times0.20.31.40.30.00.5-0.00.6-1.20.60.2
Reaction time trials completed1.01.42.11.41.21.21.21.2-0.11.21.4
Reaction time trials AUC0.71.01.51.21.01.01.01.10.11.01.2
Social response proportion0.40.42.0-0.1-0.70.1-0.80.0-1.40.1-0.4
Social responses0.20.20.40.30.20.70.10.5-0.40.60.5
Social time0.30.40.70.60.40.80.30.8-0.30.80.6
Conditioned locomotion2.02.33.81.81.31.71.01.7-0.51.91.7
Cocaine response after cond. corrected0.30.41.9-0.20.1-0.50.1-0.51.4-0.6-0.2
Cocaine response after cond. not corrected0.30.41.0-0.5-0.3-0.6-0.2-0.61.0-0.8-0.5
Cocaine response before conditioning0.20.31.7-0.1-0.5-0.0-0.4-0.0-1.30.1-0.3
Saline control response1.11.54.61.1-0.11.2-0.41.2-2.11.70.5
Condit. Reinf. active minus inactive responses1.21.52.2-1.4-1.2-1.3-1.0-1.3-0.7-1.3-1.5
Condit. Reinf. active-inactive response ratio1.31.42.2-1.4-0.9-1.4-0.6-1.4-0.1-1.5-1.4
Condit. Reinf. active responses1.52.23.0-1.4-1.7-1.3-1.7-1.3-1.4-1.1-1.7
Condit. Reinf. inactive responses0.91.12.6-0.7-1.4-0.7-1.6-0.7-1.3-0.2-0.9
Condit. Reinf. lever presses0.71.06.30.1-0.70.2-0.80.2-2.50.7-0.2
Condit. Reinf. lever reinforcers received1.21.72.7-1.1-1.6-1.1-1.6-1.1-1.6-0.8-1.4
Pavlov. Cond. lever latency0.20.21.40.00.3-0.00.3-0.01.2-0.30.0
Pavlov. Cond. magazine entry latency1.21.47.40.6-0.80.5-1.00.5-2.71.0-0.2
Pavlov. Cond. change in total contacts0.91.37.0-0.3-1.1-0.3-1.1-0.3-2.70.2-0.7
Pavlov. Cond. index score0.81.06.20.3-0.70.3-0.80.3-2.50.7-0.2
Pavlov. Cond. latency score0.60.85.00.3-0.60.3-0.60.3-2.20.6-0.2
Pavlov. Cond. lever contacts0.20.20.90.30.20.40.20.4-1.00.50.3
Pavlov. Cond. magazine entry number1.92.312.5-0.90.8-0.81.0-0.83.5-1.5-0.0
Pavlov. Cond. intertrial magazine entries0.40.51.7-0.80.1-0.60.2-0.61.3-0.9-0.3
Pavlov. Cond. lever-magazine prob. diff.0.91.17.00.4-0.70.4-0.80.4-2.60.9-0.1
Pavlov. Cond. response bias0.50.74.20.3-0.40.3-0.40.3-2.10.70.0
Conditioned reinforcement - actives0.10.10.2-0.30.3-0.20.4-0.10.5-0.20.0
Conditioned reinforcement - inactives2.62.95.6-2.1-0.4-2.0-0.0-1.91.9-2.4-1.4
Conditioned locomotion2.42.910.4-1.40.4-1.50.9-1.43.2-2.2-0.8
Intermittent access intake day 1-15 change0.30.31.00.10.8-0.11.00.10.8-0.10.5
Intermittent access intake escalation0.10.10.3-0.20.4-0.30.6-0.20.6-0.30.2
Intermittent access intake escalation 20.40.41.20.41.00.31.10.40.70.20.7
Intermitt. access day 1 inactive lever presses1.31.42.7-1.2-0.6-1.5-0.3-1.40.9-1.6-1.1
Intermitt. access day 15 inactive lever presses1.11.22.3-1.2-0.5-1.5-0.2-1.30.7-1.5-0.9
Intermitt. access escalation Index2.82.53.5-1.8-1.1-1.8-1.0-1.81.4-1.9-1.5
Intermittent access day 1 total infusions8.49.513.9-3.7-2.8-3.4-2.6-3.40.6-3.4-3.4
Intermittent access day 15 total infusions5.25.89.6-3.0-1.5-2.9-1.1-2.81.6-3.1-2.4
Intermittent access terminal intake (last 3 days)4.75.18.2-2.9-1.6-2.7-1.3-2.61.0-2.8-2.3
Intermittent access total infusions5.86.49.8-3.1-2.3-2.9-2.0-2.90.5-2.9-2.8
Intermittent access day 1 locomotion6.46.58.8-3.0-2.6-2.7-2.5-2.80.2-2.7-2.9
Intermittent access day 15 total locomotion3.84.06.3-2.5-1.4-2.4-1.1-2.31.0-2.5-2.1
Intermittent access total locomotion8.59.613.7-3.7-2.7-3.6-2.4-3.60.6-3.5-3.4
Intermittent access standard deviation0.20.31.0-0.40.3-0.40.4-0.41.0-0.6-0.1
Cocaine induced anxiety0.10.10.10.20.40.30.40.30.10.20.3
Post-drug Anxiety1.41.52.01.41.11.41.01.4-0.71.41.4
Baseline Anxiety1.81.92.91.51.01.60.81.6-1.11.71.4
Lifetime Intake5.56.19.5-3.1-2.3-2.8-2.1-2.80.4-2.7-2.7
Incentive Sensitization - Responses0.70.71.0-1.0-0.8-1.0-0.6-1.0-0.2-0.9-1.0
Incentive Sensitization - Breakpoint0.70.71.1-1.0-0.7-1.0-0.5-1.0-0.0-1.0-1.0
Progressive ratio test 1 active lever presses1.71.73.2-1.8-0.8-1.4-0.7-1.51.0-1.7-1.4
Progressive ratio test 1 breakpoint1.31.32.4-1.6-0.6-1.1-0.4-1.31.0-1.5-1.1
Progressive ratio test 1 inactive lever presses1.01.01.5-1.2-0.8-1.2-0.7-1.20.6-1.2-1.0
Progressive ratio test 2 active lever presses2.93.15.1-2.3-1.1-2.1-0.9-2.01.0-2.2-1.8
Progressive ratio test 2 breakpoint2.32.64.7-2.0-0.7-1.8-0.4-1.81.6-2.2-1.5
Progressive ratio test 2 inactive lever presses6.37.311.7-3.4-1.8-3.1-1.4-3.11.8-3.4-2.7
Total sessions with >9 infusions1.82.03.3-1.8-1.3-1.5-1.2-1.60.5-1.6-1.5
Short access day 1 total inactive lever presses2.52.84.5-2.1-1.0-1.9-0.7-1.91.4-2.1-1.6
Short access day 10 total inactive lever presses1.01.03.2-0.8-0.1-1.10.0-0.91.8-1.4-0.7
Short access day 1 total infusions5.05.38.1-2.9-2.1-2.5-2.0-2.60.5-2.5-2.5
Short access day 10 total infusions6.67.29.3-3.0-3.0-2.7-3.0-2.8-0.9-2.4-3.0
Short access total infusions3.33.65.7-2.4-2.0-1.9-2.0-2.0-0.1-1.8-2.1
Short access day 1 locomotion4.24.45.8-2.4-2.1-2.4-2.0-2.40.1-2.2-2.3
Short access day 10 total locomotion3.43.74.8-2.0-2.0-2.1-2.0-2.2-0.1-2.0-2.2
Short access total locomotion3.23.34.2-2.0-1.9-1.9-1.9-2.0-0.1-1.8-2.1
Compulsive drug intake3.23.25.62.11.32.40.92.1-0.52.21.8
One hour access (0.3 mA shock)4.75.49.7-2.7-1.1-2.7-0.8-2.62.3-3.1-2.2
One hour access (shock baseline)5.46.311.1-3.0-1.4-3.1-0.8-3.01.8-3.3-2.4
Number of responses in last shaping day0.30.31.6-0.50.2-0.30.3-0.31.3-0.5-0.1
Context. condit. distance diff. score0.81.02.1-1.1-0.3-1.0-0.1-1.01.5-1.3-0.7
Locomotion velocity, session 10.40.40.60.70.70.80.70.80.60.50.5
Locomotion distance, session 10.70.92.0-0.3-1.3-0.3-1.4-0.3-1.4-0.1-1.1
Locomotion velocity, session 20.81.03.20.9-0.10.9-0.30.9-1.81.30.4
Locomotion distance, session 20.30.51.70.3-0.80.3-1.00.3-1.30.5-0.4
Locomotion velocity, session 30.40.40.6-0.6-0.8-0.6-0.8-0.6-0.2-0.6-0.8
Locomotion distance, session 30.00.00.0-0.1-0.0-0.1-0.0-0.10.1-0.1-0.0
Stereotopy head waving bouts, day 30.70.91.1-1.0-0.9-1.0-0.9-1.00.6-1.0-1.0
Stereotopy head waving duration, day 31.01.21.7-1.3-0.9-1.3-0.9-1.30.6-1.3-1.2
Locomotion velocity, session 71.01.11.4-1.1-1.2-1.1-1.2-1.1-0.2-0.9-1.0
Locomotion distance, session 70.00.00.2-0.1-0.3-0.1-0.5-0.10.10.0-0.1
Stereotopy head waving bouts, day 71.31.52.3-1.5-1.2-1.4-1.0-1.4-0.5-1.2-1.2
Stereotopy head waving duration, day 71.11.43.6-1.0-1.4-0.9-1.4-0.9-1.9-0.3-0.9
Locomotion velocity, session 80.81.01.71.10.71.20.51.2-0.51.30.9
Locomotion distance, session 80.20.30.6-0.6-0.5-0.5-0.5-0.50.2-0.7-0.8
Degree of sensitization distance0.20.20.5-0.3-0.6-0.3-0.7-0.3-0.2-0.1-0.4
Degree of sensitization stereotypy0.60.61.9-0.8-0.8-0.7-0.8-0.7-1.4-0.2-0.4
Condit. Reinf. active minus inactive responses0.20.20.7-0.0-0.5-0.0-0.5-0.0-0.8-0.0-0.5
Condit. Reinf. active-inactive response ratio0.10.10.3-0.2-0.4-0.2-0.4-0.2-0.5-0.3-0.5
Condit. Reinf. active responses0.10.10.40.0-0.30.0-0.30.0-0.60.0-0.3
Condit. Reinf. inactive responses0.00.00.1-0.2-0.2-0.2-0.2-0.2-0.1-0.1-0.2
Incentive salience index mean0.20.31.00.0-0.6-0.0-0.7-0.0-1.00.1-0.5
Condit. Reinf. lever presses0.10.20.50.50.00.40.00.4-0.70.40.1
Time in familiar zone, hab. session 10.70.61.0-0.8-0.9-0.8-0.8-0.8-0.1-0.9-1.0
Time in novel zone, hab. session 10.50.51.20.60.90.50.80.51.10.40.7
Total zone transitions, hab. session 10.30.41.30.5-0.10.7-0.30.7-1.10.70.1
Total locomotion distance, hab. session 10.20.30.5-0.5-0.4-0.5-0.3-0.50.4-0.7-0.6
Locomotion velocity, hab. session 10.00.10.1-0.2-0.3-0.1-0.3-0.10.0-0.3-0.4
Time in familiar zone, hab. session 20.70.70.90.90.90.90.70.90.70.80.9
Time in novel zone, hab. session 20.80.81.2-0.8-1.1-0.8-1.0-0.8-0.9-0.7-1.0
Total zone transitions, hab. session 22.43.16.7-1.0-2.3-1.0-2.6-1.0-2.4-0.5-1.8
Total locomotion distance, hab. session 21.31.73.0-1.2-1.6-1.2-1.7-1.2-0.7-1.0-1.6
Locomotion velocity, hab. session 21.52.03.0-1.4-1.7-1.3-1.7-1.3-0.6-1.2-1.7
Novel to familiar place preference ratio0.50.62.8-0.4-0.8-0.4-0.7-0.4-1.7-0.1-0.5
Novelty place preference0.60.61.7-0.6-0.9-0.7-0.8-0.7-1.3-0.4-0.7
Time in novel zone, NPP test0.60.61.3-0.6-0.9-0.7-0.8-0.7-1.2-0.4-0.7
Total zone transitions, NPP test0.60.84.10.4-0.70.5-0.90.5-2.00.7-0.4
Total locomotion distance, NPP test0.10.20.4-0.2-0.5-0.2-0.6-0.2-0.4-0.2-0.6
Locomotion velocity, NPP test0.10.10.3-0.1-0.4-0.1-0.5-0.1-0.4-0.1-0.5
Pavlov. Cond. lever latency0.00.10.30.10.2-0.10.3-0.10.6-0.20.1
Pavlov. Cond. magazine entry latency0.91.21.9-1.0-1.4-1.0-1.3-1.0-1.1-0.8-1.2
Pavlov. Cond. change in total contacts0.50.60.7-0.8-0.8-0.7-0.6-0.7-0.8-0.7-0.9
Pavlov. Cond. index score0.00.00.2-0.2-0.2-0.1-0.1-0.1-0.5-0.1-0.2
Pavlov. Cond. latency score0.10.10.1-0.3-0.4-0.2-0.3-0.2-0.3-0.3-0.4
Pavlov. Cond. lever contacts0.00.00.0-0.1-0.10.0-0.10.0-0.0-0.0-0.1
Pavlov. Cond. magazine entry number0.00.00.3-0.0-0.0-0.1-0.1-0.10.6-0.0-0.0
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.20.5-0.00.6-0.00.6-0.10.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.5-0.1-0.3-0.0-0.2-0.0-0.70.0-0.2
Pavlov. Cond. response bias0.00.00.20.0-0.00.00.10.0-0.4-0.0-0.0
Bone: apparent density2.23.66.4-1.5-2.4-1.6-2.5-1.6-2.2-0.9-2.0
Bone surface1.83.215.0-0.5-2.0-0.4-2.2-0.4-3.90.5-1.1
Bone volume1.83.08.3-1.1-2.1-1.1-2.2-1.1-2.9-0.4-1.6
Bone: connectivity density1.93.09.3-0.8-2.2-0.8-2.4-0.8-3.10.0-1.4
Bone: cortical apparent density0.30.40.60.80.60.70.40.7-0.10.80.8
Bone: cortical area0.60.91.40.90.81.00.81.0-0.81.21.1
Bone: cortical porosity0.50.51.1-0.5-1.0-0.6-1.0-0.6-0.7-0.4-0.8
Bone: cortical porosity0.30.30.9-0.1-0.7-0.1-0.8-0.1-0.90.2-0.3
Bone: cortical thickness4.27.010.52.92.43.02.13.0-0.93.23.0
Bone: cortical thickness2.83.34.42.01.82.01.62.00.22.02.1
Bone: cortical tissue density0.40.60.90.90.60.80.50.8-0.10.90.9
Bone: elastic displacement1.61.83.71.11.61.01.61.01.90.61.3
Bone: elastic work2.33.04.12.01.71.91.41.90.22.02.0
Bone: endosteal estimation1.94.25.7-2.3-2.0-2.2-1.8-2.20.2-2.3-2.4
Bone: endosteal perimeter3.47.010.1-2.9-2.6-2.8-2.3-2.8-0.3-3.0-3.2
Bone: final force0.81.34.11.00.11.1-0.11.1-2.01.50.7
Bone: final moment0.71.13.60.90.11.0-0.11.0-1.91.40.6
Bone: marrow area2.04.35.8-2.3-2.0-2.2-1.8-2.20.2-2.3-2.4
Bone: maximum diameter0.00.10.4-0.00.10.10.20.1-0.60.0-0.0
Bone: maximum force1.01.79.70.1-1.10.2-1.30.2-3.10.8-0.5
Bone: maximum moment0.91.58.30.1-1.10.2-1.30.2-2.90.7-0.5
Bone: minimum diameter2.75.06.3-2.5-2.4-2.5-2.2-2.5-0.4-2.2-2.5
Bone: periosteal estimation0.20.30.5-0.7-0.5-0.6-0.4-0.6-0.4-0.5-0.6
Bone: periosteal perimeter0.40.61.0-0.7-0.9-0.7-0.9-0.7-1.0-0.5-0.9
Bone: post-yield work7.810.715.6-2.9-4.0-2.9-3.9-2.9-3.1-2.4-3.6
Bone: stiffness1.11.78.5-0.4-1.4-0.3-1.5-0.3-2.90.3-0.8
Bone: tissue strength0.30.30.5-0.4-0.6-0.4-0.6-0.4-0.7-0.4-0.7
Bone: trabecular number1.93.05.2-1.4-2.2-1.4-2.2-1.4-2.3-0.8-1.7
Bone: trabecular spacing0.30.41.20.40.70.40.70.41.10.10.5
Bone: trabecular thickness1.92.33.0-1.6-1.7-1.6-1.6-1.6-0.5-1.4-1.7
Bone: trabecular tissue density1.01.45.7-0.80.5-0.90.8-0.92.4-1.5-0.4
Breakpoint value in progressive ratio session1.21.43.91.20.31.20.11.1-2.01.50.8
Distance traveled before self-admin0.10.10.50.1-0.00.2-0.00.1-0.70.30.0
Distance traveled after self-admin0.00.00.3-0.0-0.0-0.00.00.1-0.60.1-0.1
Delta time in closed arm before/after self-admin0.60.61.01.00.70.70.50.70.41.00.9
Delta time in open arm before/after self-admin0.00.00.1-0.30.10.10.2-0.1-0.3-0.10.1
Diff in mean of infusions in LGA sessions0.40.50.80.60.60.80.60.7-0.50.80.9
Extinction: sum of active levers before priming1.31.36.10.7-0.40.9-0.60.8-2.51.30.4
Active lever presses in extinction session 62.32.23.51.91.21.61.21.5-1.01.71.6
Delta distance traveled before/after self-admin0.00.00.00.00.20.10.20.10.10.00.1
Delta ambulatory time before/after self-admin0.10.10.10.30.30.30.20.20.20.20.3
Time in closed arm before self-admin0.20.30.5-0.6-0.5-0.3-0.5-0.2-0.5-0.5-0.7
Time in closed arm after self-admin0.00.00.00.0-0.10.0-0.10.10.10.0-0.0
Time in open arm before self-admin0.20.21.10.40.30.10.10.11.10.10.2
Time in open arm after self-admin0.20.20.60.30.60.30.60.20.80.10.5
Sum of active levers in priming session hrs 5-62.62.53.31.81.71.61.81.4-0.71.51.8
Time to tail flick, vehicle, before self-admin0.20.20.9-0.1-0.6-0.1-0.7-0.1-1.00.1-0.3
Time to tail flick, vehicle, after self-admin0.40.41.30.4-0.40.4-0.70.6-1.20.80.1
Time to tail flick, test, before self-admin1.21.21.9-1.0-1.3-1.0-1.4-1.00.1-1.0-1.4
Time to tail flick, test, after self-admin0.00.00.00.10.20.10.20.2-0.00.10.1
Delta time to tail flick, vehicle, before/after SA0.20.20.60.3-0.30.2-0.50.3-0.70.4-0.1
Delta time to tail flick, test, before/after SA3.02.73.91.71.81.61.81.70.01.62.0
Ambulatory time before self-admin0.10.21.0-0.1-0.3-0.1-0.2-0.2-1.0-0.0-0.3
Ambulatory time after self-admin1.01.11.5-1.2-1.0-1.2-0.9-1.2-0.7-1.1-1.2
Total heroin consumption2.12.55.11.70.51.80.31.6-2.32.11.4
Area under the delay curve0.80.91.6-0.7-1.1-0.9-1.2-0.7-0.2-0.8-1.3
Delay disc. indifference point, 0s delay0.80.81.1-0.9-0.9-0.9-1.0-0.90.6-0.9-1.0
Delay disc. indifference point, 16s delay1.91.93.0-1.4-1.3-1.7-1.1-1.40.0-1.6-1.6
Delay disc. indifference point, 2s delay0.20.30.6-0.5-0.5-0.5-0.5-0.50.1-0.6-0.8
Delay disc. indifference point, 24s delay0.20.20.50.50.40.30.30.50.70.30.3
Delay disc. indifference point, 4s delay0.30.30.7-0.4-0.7-0.6-0.8-0.40.3-0.5-0.7
Delay disc. indifference point, 8s delay0.20.30.6-0.3-0.6-0.4-0.8-0.30.1-0.4-0.8
Delay discount exponential model param0.50.61.20.50.90.71.00.50.20.61.1
Delay discount hyperbolic model param0.40.51.00.50.90.60.90.50.20.61.0
Fecal boli incidents, locomotor time 10.10.10.2-0.4-0.0-0.40.1-0.3-0.4-0.20.1
Change in fecal boli incidents, locomotor task0.10.10.40.1-0.5-0.2-0.6-0.1-0.0-0.0-0.5
Time >=10cm from walls, locomotor time 14.04.05.3-2.2-2.0-2.3-1.9-2.1-0.6-2.0-2.3
Bouts of movement, locomotor time 10.40.51.50.70.20.60.10.7-1.20.80.5
Total resting periods, locomotor time 10.20.31.50.3-0.10.2-0.10.3-1.20.50.1
Rest time, locomotor task time 10.40.41.7-0.40.4-0.50.6-0.41.3-0.9-0.3
Distance moved, locomotor task time 10.50.61.2-0.4-1.0-0.6-1.1-0.7-0.9-0.2-0.7
Vertical activity count, locomotor time 10.40.41.1-0.5-0.1-0.80.0-0.71.0-0.7-0.2
Time >=10cm from walls, locomotor time 20.10.10.2-0.5-0.3-0.4-0.2-0.4-0.3-0.4-0.4
Bouts of movement, locomotor time 20.20.20.70.3-0.10.4-0.20.3-0.80.50.2
Total resting periods, locomotor time 20.10.10.50.0-0.30.1-0.40.0-0.70.2-0.1
Rest time, locomotor task time 21.01.22.5-1.1-0.3-1.3-0.1-1.01.6-1.4-0.9
Distance moved, locomotor task time 20.60.71.21.10.40.80.30.8-1.01.10.7
Vertical activity count, locomotor time 21.71.92.61.61.61.21.61.30.91.21.6
Weight adjusted by age1.41.62.71.50.71.30.51.4-1.41.61.1
Seeking ratio, delayed vs. immediate footshock0.60.71.2-0.7-1.0-0.7-1.1-0.7-0.5-0.6-1.1
Locomotion in novel chamber2.02.55.1-1.7-0.4-1.80.0-1.81.9-2.3-1.4
Locomotion in novel chamber post-restriction1.11.32.7-1.2-0.2-1.20.0-1.21.6-1.6-0.9
Progressive ratio1.82.15.8-0.8-1.8-0.8-2.0-0.7-2.4-0.1-1.2
Food seeking constrained by brief footshock0.30.40.70.80.50.70.30.7-0.10.90.7
Seeking ratio, punishment vs. effort1.41.75.50.91.60.81.70.72.30.21.0
Run reversals in cocaine runway, females0.40.41.4-0.2-0.9-0.2-1.2-0.2-0.90.2-0.5
Run reversals in cocaine runway, males2.62.64.21.32.01.42.01.41.51.01.8
Latency to leave start box in cocaine runway0.91.01.4-0.9-1.2-1.0-1.2-1.0-0.8-0.8-1.2
Latency to leave start box in cocaine runway, F0.40.40.7-0.5-0.8-0.6-0.8-0.6-0.6-0.5-0.8
Latency to leave start box in cocaine runway, M0.10.10.1-0.2-0.2-0.2-0.2-0.2-0.3-0.2-0.2
Cd content in liver0.40.51.6-0.60.4-0.50.6-0.61.3-0.8-0.2
Co content in liver1.21.55.60.61.40.71.40.72.40.30.8
Cu content in liver0.10.10.60.0-0.3-0.0-0.40.0-0.80.30.1
Fe content in liver0.10.10.20.40.40.40.40.4-0.10.50.2
K content in liver0.90.93.8-0.1-1.10.0-1.30.1-2.00.4-0.4
Mg content in liver2.93.05.5-1.6-2.2-1.5-2.3-1.4-1.6-1.1-1.8
Mn content in liver0.80.94.30.6-0.10.8-0.30.8-2.11.10.3
Na content in liver0.90.91.31.10.91.10.91.1-0.61.00.8
Rb content in liver2.32.93.8-1.9-1.6-1.9-1.6-1.90.5-1.8-1.8
Se content in liver0.91.11.5-1.2-1.2-1.1-1.1-1.0-1.1-0.9-0.9
Sr content in liver2.62.43.41.71.31.71.21.7-0.91.81.7
Zn content in liver0.40.41.50.5-0.10.5-0.30.6-1.20.80.6