Slc29a1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000019752 0.14 0.07 2.2e-12 0.11 0.11 0.11 0.11 2.6e-12 4.3e-12 4.2e-12 5.9e-12
2 Brain gene expression ENSRNOG00000019752 0.04 0.03 2.6e-03 0.04 0.03 0.04 0.04 1.7e-04 8.3e-04 2.5e-04 3.3e-04
3 IL gene expression ENSRNOG00000019752 0.15 0.08 3.8e-03 -0.01 0.03 0.02 0.02 5.3e-01 7.2e-02 1.3e-01 1.0e-01
4 Liver alternative TSS ENSRNOT00000111451 0.13 0.06 3.7e-15 0.14 0.14 0.14 0.14 2.9e-15 2.1e-15 1.1e-15 1.3e-15
5 Liver alternative TSS ENSRNOT00000107209 0.03 0.02 3.7e-03 0.01 0.01 0.02 0.01 1.7e-02 2.9e-02 1.3e-03 1.8e-02
6 Liver gene expression ENSRNOG00000019752 0.08 0.04 1.1e-07 0.04 0.05 0.04 0.05 1.2e-05 2.3e-06 9.3e-06 6.0e-06
7 Liver isoform ratio ENSRNOT00000026831 0.05 0.04 1.3e-03 0.01 0.02 0.01 0.01 3.8e-02 2.3e-03 3.0e-02 2.6e-02
8 Liver isoform ratio ENSRNOT00000111451 0.06 0.03 1.3e-06 0.06 0.05 0.05 0.05 1.7e-07 1.3e-06 1.2e-06 1.4e-06
9 Liver intron excision ratio chr9:15399733:15405034 0.19 0.07 0.0e+00 0.2 0.19 0.2 0.19 2.2e-21 2.5e-20 3.2e-21 4.8e-21
10 Liver intron excision ratio chr9:15403262:15405034 0.12 0.05 4.5e-15 0.14 0.13 0.14 0.14 8.0e-16 2.5e-14 3.2e-15 5.3e-15
11 NAcc gene expression ENSRNOG00000019752 0.13 0.06 1.1e-10 0.14 0.15 0.15 0.15 5.8e-11 4.1e-11 5.7e-11 3.9e-11
12 OFC gene expression ENSRNOG00000019752 0.16 0.1 8.6e-03 0.03 0.02 0.01 0.01 8.3e-02 1.0e-01 1.9e-01 1.4e-01
13 PL gene expression ENSRNOG00000019752 0.05 0.03 6.7e-04 0.06 0.04 0.04 0.04 2.9e-05 7.3e-04 8.3e-04 3.5e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail3.110.016.2-3.90.32.0-3.4-2.93.33.6-3.7-3.73.72.84.00.5
BMI without tail10.321.534.2-5.81.03.5-4.3-4.04.75.1-5.5-5.55.54.85.81.8
Body weight1.97.911.4-3.21.92.9-3.4-2.02.52.9-2.9-2.92.93.23.32.0
Epididymis fat weight2.35.511.2-2.92.13.0-2.0-1.12.02.1-1.9-1.91.93.32.92.1
Glucose1.62.55.3-2.00.81.3-2.3-1.31.41.8-1.6-1.61.61.61.90.3
Heart weight1.31.85.51.2-0.2-0.61.12.4-2.0-2.01.31.3-1.3-0.7-1.20.5
Left kidney weight0.30.82.0-1.2-0.50.2-0.3-0.30.20.3-1.4-1.41.40.81.20.4
Right kidney weight0.30.71.4-1.1-1.1-0.50.10.5-0.5-0.3-1.2-1.21.20.41.1-0.8
Tail length1.64.96.7-2.41.42.3-2.0-1.71.82.3-2.4-2.42.42.62.42.3
Length with tail0.31.04.60.32.01.4-0.50.9-0.7-0.40.30.3-0.30.9-0.22.1
Length without tail2.04.37.62.81.4-0.30.92.2-2.3-2.32.62.6-2.6-1.5-2.70.6
Liver weight, left0.20.41.0-0.8-0.3-0.2-0.8-0.70.61.0-0.5-0.50.50.00.9-0.3
Liver weight, right1.22.06.0-0.51.61.2-2.2-2.52.02.1-0.8-0.80.80.30.60.4
Parametrial fat weight4.69.013.3-3.31.62.3-3.6-2.52.93.3-3.7-3.73.72.63.41.0
Retroperitoneal fat weight0.92.97.5-2.30.41.2-2.7-1.31.72.2-1.6-1.61.61.42.30.1
Intraocular pressure0.20.30.70.50.20.30.7-0.80.80.20.80.8-0.8-0.1-0.50.2
Extensor digitorum longus weight0.20.92.1-0.81.00.7-1.4-1.20.91.3-0.8-0.80.80.40.80.4
Soleus weight0.41.12.9-0.90.70.6-1.6-1.71.31.7-0.8-0.80.80.30.8-0.2
Tibialis anterior weight0.30.92.0-1.10.30.2-1.0-1.10.91.4-1.1-1.11.10.31.1-0.7
Tibia length0.41.04.9-0.5-1.6-1.20.4-1.00.40.9-0.5-0.50.5-0.90.4-2.2
Number of licking bursts0.60.72.7-0.41.11.2-1.6-0.50.70.5-0.7-0.70.70.90.40.6
Food consumed during 24 hour testing period0.30.31.10.0-0.2-0.1-1.0-0.40.10.0-1.0-1.01.0-0.10.0-0.1
Times rat made contact with spout0.30.41.1-0.90.30.70.1-0.40.50.3-0.4-0.40.41.00.90.9
Mean time between licks in bursts0.81.24.41.10.1-0.42.10.9-1.1-1.51.11.1-1.1-0.6-1.1-0.1
Mean num. licks in bursts0.50.64.3-0.1-1.0-0.92.10.4-0.6-0.50.60.6-0.6-0.40.1-0.0
Std. dev. time between licks in bursts0.80.92.51.1-0.5-1.01.60.5-0.5-0.80.90.9-0.9-1.1-1.1-0.7
Water consumed over 24 hours0.80.92.8-1.0-0.60.1-0.5-0.30.00.5-1.7-1.71.70.71.00.1
Indifference point 0 sec0.40.61.6-1.2-0.20.21.00.8-0.2-0.2-1.0-1.01.00.91.30.3
Indifference point AUC0.91.15.0-0.4-2.0-1.60.90.7-0.30.2-0.1-0.10.1-0.90.4-2.2
Indifference point function ln k0.60.92.5-0.91.31.3-0.5-0.80.90.3-0.5-0.50.51.30.81.6
Indifference point function log k0.60.92.5-0.91.31.3-0.5-0.80.90.3-0.5-0.50.51.30.81.6
Delay discounting total patch changes 0 sec0.40.71.9-1.3-0.30.20.80.7-0.1-0.1-1.0-1.01.00.91.40.3
Delay discounting total patch changes 12 sec1.01.32.9-1.4-1.3-0.4-0.70.7-0.10.6-1.7-1.71.70.51.4-0.7
Delay discounting total patch changes 18 sec0.60.82.60.2-1.1-1.11.61.3-1.1-0.70.60.6-0.6-0.6-0.1-1.0
Delay discounting total patch changes 24 sec0.60.71.6-1.2-0.9-0.40.21.1-0.20.3-1.2-1.21.20.41.3-0.3
Delay discounting total patch changes 6 sec0.81.22.8-1.6-0.80.0-0.30.40.10.5-1.6-1.61.60.91.7-0.3
Delay discounting time to switch 0 sec1.32.04.32.00.60.3-0.11.0-1.3-1.71.71.7-1.7-0.4-2.11.5
Delay discounting water rate 0 sec0.91.44.1-1.5-1.2-1.10.70.3-0.10.7-1.3-1.31.3-0.31.5-2.0
Delay discounting water rate 12 sec2.63.97.2-2.4-0.30.3-2.7-1.91.82.7-2.1-2.12.10.62.5-1.7
Delay discounting water rate 18 sec1.31.73.8-1.90.10.6-1.3-0.71.01.2-1.7-1.71.71.11.90.1
Delay discounting water rate 24 sec3.04.27.1-2.61.21.1-2.3-1.82.22.3-2.4-2.42.41.42.7-0.3
Delay discounting water rate 6 sec0.40.62.8-0.6-1.0-1.0-0.2-0.30.30.8-0.7-0.70.7-0.80.5-1.7
Locomotor activity1.62.65.6-1.32.42.1-1.1-1.31.21.2-1.4-1.41.41.91.32.2
Locomotor testing distance1.32.15.1-1.32.31.8-1.1-0.70.71.1-1.4-1.41.41.61.31.8
Locomotor testing rearing1.32.04.3-1.61.31.1-1.5-1.91.52.1-1.3-1.31.30.81.60.0
Light reinforcement 10.40.81.7-0.9-0.10.3-0.6-0.90.81.0-1.3-1.31.30.40.90.1
Light reinforcement 20.71.02.7-0.70.90.9-0.6-1.61.11.1-1.1-1.11.10.70.60.6
Reaction time number correct1.31.85.30.1-2.3-2.30.41.6-1.5-0.9-0.1-0.10.1-1.6-0.1-2.3
Reaction time mean minus median0.30.41.80.21.20.8-0.50.3-0.3-0.30.30.3-0.30.2-0.31.4
Reaction time mean minus median AUC0.40.51.80.51.40.6-0.10.5-0.6-0.70.60.6-0.6-0.0-0.71.0
Reaction time num false alarms0.50.73.70.1-1.4-0.81.91.3-0.9-0.8-0.0-0.00.0-0.2-0.0-0.5
Reaction time num false alarms AUC0.40.52.4-0.2-1.3-0.71.61.0-0.5-0.5-0.4-0.40.4-0.00.2-0.3
Reaction time trials correct on left1.31.85.30.1-2.3-2.30.41.6-1.5-0.9-0.1-0.10.1-1.6-0.1-2.3
Reaction time trials on left1.21.75.00.1-2.2-2.20.31.5-1.4-0.8-0.1-0.10.1-1.5-0.1-2.2
Reaction time mean1.72.38.7-0.72.62.4-0.6-1.41.40.9-0.4-0.40.41.70.62.9
Reaction time mean AUC1.41.97.2-0.62.62.2-0.5-1.21.10.8-0.2-0.20.21.50.52.7
Median of all reaction times2.12.99.1-0.92.62.5-0.7-1.81.81.3-0.7-0.70.71.90.93.0
Reaction time omissions0.50.72.0-0.80.81.2-0.3-0.40.70.7-0.7-0.70.71.10.81.4
Reaction time false alarm rate0.20.21.9-0.1-0.10.41.40.20.1-0.1-0.1-0.10.10.60.10.6
Reaction time premature initiation rate0.20.30.8-0.80.40.4-0.90.20.50.5-0.4-0.40.40.50.7-0.3
Reaction time premature initiations0.30.51.6-0.8-0.6-0.6-1.00.9-0.20.1-0.5-0.50.5-0.20.8-1.3
Std. dev. reaction times1.01.35.0-0.42.21.9-0.7-0.80.80.5-0.1-0.10.11.30.32.2
Reaction time trials completed1.21.75.00.1-2.2-2.20.31.5-1.4-0.8-0.1-0.10.1-1.5-0.1-2.2
Reaction time trials AUC1.11.64.9-0.0-2.2-2.10.21.4-1.3-0.7-0.2-0.20.2-1.50.0-2.2
Social response proportion0.30.30.80.8-0.2-0.00.60.3-0.4-0.60.50.5-0.5-0.2-0.70.9
Social responses0.20.31.40.40.00.20.1-0.0-0.00.00.80.8-0.80.0-0.41.2
Social time0.81.16.4-0.2-2.5-1.70.3-0.2-0.30.3-0.4-0.40.4-1.10.1-1.7
Conditioned locomotion1.21.43.10.9-1.8-1.60.91.2-1.2-1.00.90.9-0.9-1.3-0.9-1.6
Cocaine response after cond. corrected0.30.40.90.60.40.20.8-0.20.1-0.21.01.0-1.0-0.1-0.6-0.4
Cocaine response after cond. not corrected0.70.81.81.00.2-0.11.00.3-0.3-0.71.41.4-1.4-0.5-1.0-0.5
Cocaine response before conditioning1.11.41.81.2-1.2-1.31.11.1-1.3-1.21.11.1-1.1-1.3-1.2-0.8
Saline control response0.30.30.90.7-0.8-0.90.10.4-0.5-0.30.40.4-0.4-1.0-0.6-0.5
Condit. Reinf. active minus inactive responses0.60.72.10.7-0.3-0.91.00.4-0.6-0.30.90.9-0.9-1.3-0.7-1.4
Condit. Reinf. active-inactive response ratio0.30.40.90.50.3-0.40.70.3-0.4-0.10.70.7-0.7-0.8-0.4-1.0
Condit. Reinf. active responses0.91.32.30.8-1.1-1.51.40.9-1.1-0.81.01.0-1.0-1.5-0.8-1.5
Condit. Reinf. inactive responses0.60.81.80.5-1.3-1.20.91.2-1.2-1.10.40.4-0.4-0.9-0.5-0.6
Condit. Reinf. lever presses0.10.10.2-0.3-0.2-0.3-0.1-0.0-0.00.2-0.4-0.40.4-0.30.3-0.4
Condit. Reinf. lever reinforcers received0.81.12.30.7-1.1-1.41.20.6-0.9-0.60.90.9-0.9-1.5-0.7-1.5
Pavlov. Cond. lever latency0.10.10.40.2-0.5-0.30.20.6-0.2-0.70.10.1-0.10.1-0.2-0.1
Pavlov. Cond. magazine entry latency0.70.92.4-0.80.50.5-1.5-1.30.81.5-0.8-0.80.80.20.9-0.4
Pavlov. Cond. change in total contacts0.50.61.2-0.91.10.8-0.5-0.70.61.1-0.8-0.80.80.71.00.3
Pavlov. Cond. index score0.81.02.3-1.10.60.6-1.5-1.10.81.5-1.1-1.11.10.41.1-0.0
Pavlov. Cond. latency score1.01.32.8-1.20.60.7-1.6-1.30.91.7-1.3-1.31.30.51.30.0
Pavlov. Cond. lever contacts0.20.30.7-0.60.70.6-0.5-0.60.30.8-0.5-0.50.50.30.60.5
Pavlov. Cond. magazine entry number0.40.51.50.7-0.5-0.41.20.8-0.4-1.20.70.7-0.7-0.2-0.80.2
Pavlov. Cond. intertrial magazine entries0.40.51.70.50.00.11.01.3-0.7-1.20.60.6-0.60.2-0.60.8
Pavlov. Cond. lever-magazine prob. diff.1.01.32.7-1.20.70.8-1.6-1.21.01.6-1.3-1.31.30.71.30.2
Pavlov. Cond. response bias0.00.00.2-0.10.40.2-0.30.1-0.40.20.00.0-0.0-0.20.10.2
Conditioned reinforcement - actives0.80.82.80.8-1.3-1.30.9-0.1-0.30.10.60.6-0.6-1.3-0.8-1.7
Conditioned reinforcement - inactives0.20.21.10.2-0.2-0.41.1-0.80.10.40.10.1-0.1-0.4-0.2-0.7
Conditioned locomotion0.00.10.2-0.00.10.2-0.5-0.40.20.4-0.0-0.00.0-0.00.00.0
Intermittent access intake day 1-15 change0.30.30.50.60.40.0-0.4-0.4-0.0-0.00.70.7-0.7-0.4-0.70.5
Intermittent access intake escalation0.70.71.41.10.70.00.0-0.3-0.1-0.41.21.2-1.2-0.6-1.20.7
Intermittent access intake escalation 20.20.20.50.6-0.3-0.50.30.3-0.6-0.50.60.6-0.6-0.5-0.70.2
Intermitt. access day 1 inactive lever presses0.91.03.2-0.01.61.2-0.9-1.81.31.0-0.3-0.30.30.60.01.1
Intermitt. access day 15 inactive lever presses0.30.40.7-0.60.70.7-0.5-0.30.30.1-0.8-0.80.80.70.60.5
Intermitt. access escalation Index1.21.12.1-1.30.40.6-1.1-1.21.41.2-1.0-1.01.00.61.40.4
Intermittent access day 1 total infusions0.40.51.1-0.50.30.91.1-0.70.70.5-0.4-0.40.40.90.51.0
Intermittent access day 15 total infusions0.40.41.60.40.90.80.3-0.80.50.20.60.6-0.60.3-0.51.3
Intermittent access terminal intake (last 3 days)0.20.31.20.30.50.70.4-0.60.40.30.30.3-0.30.4-0.31.1
Intermittent access total infusions0.20.20.80.0-0.00.40.9-0.60.50.20.20.2-0.20.4-0.10.8
Intermittent access day 1 locomotion0.60.61.3-0.60.81.1-0.0-1.01.10.9-0.5-0.50.50.90.71.0
Intermittent access day 15 total locomotion0.20.30.80.50.10.00.9-0.1-0.1-0.30.70.7-0.7-0.1-0.60.5
Intermittent access total locomotion0.30.41.00.6-0.3-0.21.00.5-0.4-0.70.80.8-0.8-0.2-0.70.4
Intermittent access standard deviation0.80.81.91.00.20.01.40.5-0.8-0.91.11.1-1.1-0.2-1.11.2
Cocaine induced anxiety0.20.20.50.50.70.30.1-0.60.4-0.00.50.5-0.5-0.0-0.50.1
Post-drug Anxiety1.01.13.11.11.80.90.10.6-0.5-0.91.31.3-1.30.0-1.11.4
Baseline Anxiety1.21.22.91.10.70.20.41.7-1.5-1.41.21.2-1.2-0.2-1.11.0
Lifetime Intake0.20.21.40.4-0.20.11.2-0.20.1-0.20.60.6-0.6-0.0-0.40.4
Incentive Sensitization - Responses0.90.91.9-1.1-0.10.4-0.7-1.11.31.4-1.1-1.11.10.81.1-0.4
Incentive Sensitization - Breakpoint0.70.71.5-1.0-0.20.2-0.5-0.91.11.2-0.9-0.90.90.60.9-0.5
Progressive ratio test 1 active lever presses1.11.12.8-0.41.71.5-0.1-1.71.61.2-0.2-0.20.20.90.31.3
Progressive ratio test 1 breakpoint1.11.13.0-0.21.71.5-0.0-1.71.51.10.00.0-0.00.80.11.4
Progressive ratio test 1 inactive lever presses0.70.81.9-0.51.41.2-0.2-1.11.00.9-0.6-0.60.60.80.61.0
Progressive ratio test 2 active lever presses0.50.52.2-0.30.60.8-0.1-1.51.41.2-0.2-0.20.20.50.20.2
Progressive ratio test 2 breakpoint0.60.72.2-0.60.60.9-0.1-1.51.51.3-0.5-0.50.50.70.50.3
Progressive ratio test 2 inactive lever presses0.20.21.2-0.1-0.4-0.21.1-0.70.40.4-0.2-0.20.2-0.00.0-0.5
Total sessions with >9 infusions0.10.10.2-0.40.10.2-0.1-0.20.40.4-0.4-0.40.40.10.40.0
Short access day 1 total inactive lever presses0.20.31.4-0.3-0.6-0.50.1-0.40.50.4-0.3-0.30.3-0.40.3-1.2
Short access day 10 total inactive lever presses0.40.51.1-0.7-0.4-0.2-1.0-0.20.00.3-1.0-1.01.00.10.7-0.6
Short access day 1 total infusions0.20.20.8-0.5-0.4-0.20.2-0.70.50.5-0.3-0.30.3-0.20.5-0.9
Short access day 10 total infusions0.20.31.30.30.30.60.8-0.40.3-0.00.40.4-0.40.3-0.21.1
Short access total infusions0.10.10.90.3-0.00.01.00.2-0.1-0.30.40.4-0.4-0.1-0.20.2
Short access day 1 locomotion0.10.10.50.30.2-0.3-0.3-0.10.10.10.20.2-0.2-0.7-0.2-0.3
Short access day 10 total locomotion0.60.61.11.1-0.0-0.30.50.9-0.8-0.81.01.0-1.0-0.6-1.00.2
Short access total locomotion0.50.50.70.7-0.4-0.60.70.8-0.8-0.70.70.7-0.7-0.8-0.7-0.4
Compulsive drug intake0.20.20.80.3-0.5-0.8-0.60.4-0.1-0.20.10.1-0.1-0.9-0.3-0.4
One hour access (0.3 mA shock)0.80.92.71.0-1.6-1.31.40.0-0.4-0.10.70.7-0.7-1.3-1.0-0.7
One hour access (shock baseline)0.20.31.3-0.00.10.41.1-0.90.50.60.10.1-0.10.4-0.10.5
Number of responses in last shaping day0.70.73.3-0.70.00.1-0.2-1.81.21.2-0.6-0.60.60.20.7-0.9
Context. condit. distance diff. score1.62.03.8-1.60.60.9-1.6-1.41.31.9-1.7-1.71.70.91.60.2
Locomotion velocity, session 11.21.32.80.8-1.7-1.51.20.9-1.3-0.90.80.8-0.8-1.1-0.8-1.4
Locomotion distance, session 10.40.51.9-0.2-0.4-0.5-1.4-0.70.31.0-0.5-0.50.5-0.60.2-1.3
Locomotion velocity, session 21.82.24.3-1.6-0.30.6-2.1-1.21.42.0-1.8-1.81.81.01.6-0.5
Locomotion distance, session 20.40.51.5-0.7-0.8-0.4-1.0-0.10.41.0-0.8-0.80.8-0.10.7-1.2
Locomotion velocity, session 30.40.41.7-0.3-1.3-0.6-0.6-0.60.50.9-0.5-0.50.5-0.40.4-0.8
Locomotion distance, session 30.20.20.9-0.0-1.0-0.80.20.0-0.30.0-0.0-0.00.0-0.60.0-0.9
Stereotopy head waving bouts, day 30.20.21.20.10.50.5-1.10.5-0.4-0.3-0.0-0.00.00.4-0.10.2
Stereotopy head waving duration, day 30.20.21.0-0.4-0.20.2-1.0-0.20.50.5-0.5-0.50.50.30.4-0.2
Locomotion velocity, session 70.70.81.41.0-0.6-1.10.20.8-1.0-0.70.80.8-0.8-1.2-1.0-0.8
Locomotion distance, session 70.40.51.90.2-1.1-1.30.30.0-0.5-0.00.30.3-0.3-1.1-0.3-1.4
Stereotopy head waving bouts, day 70.30.40.8-0.60.50.6-0.9-0.10.20.4-0.8-0.80.80.70.6-0.1
Stereotopy head waving duration, day 70.20.20.7-0.20.80.7-0.8-0.10.20.2-0.4-0.40.40.50.20.4
Locomotion velocity, session 80.30.41.00.8-0.5-0.7-0.50.2-0.5-0.00.40.4-0.4-1.0-0.7-0.9
Locomotion distance, session 81.01.43.8-1.2-0.4-0.1-1.7-1.01.02.0-1.4-1.41.4-0.01.2-1.1
Degree of sensitization distance0.10.10.3-0.0-0.4-0.40.30.0-0.10.10.00.0-0.0-0.2-0.0-0.5
Degree of sensitization stereotypy0.10.10.3-0.30.10.3-0.50.3-0.10.1-0.6-0.60.60.30.4-0.3
Condit. Reinf. active minus inactive responses0.91.02.61.30.1-0.80.1-0.2-0.40.01.21.2-1.2-1.6-1.3-1.3
Condit. Reinf. active-inactive response ratio0.40.40.70.70.7-0.10.7-0.30.10.10.90.9-0.9-0.8-0.7-0.4
Condit. Reinf. active responses0.50.61.50.90.1-0.5-0.5-0.90.20.70.70.7-0.7-1.2-0.9-1.1
Condit. Reinf. inactive responses0.60.72.6-0.5-0.00.5-1.6-1.10.91.1-0.8-0.80.80.40.50.1
Incentive salience index mean0.50.61.80.6-0.0-0.6-0.8-0.90.40.90.40.4-0.4-1.2-0.6-1.3
Condit. Reinf. lever presses0.91.23.5-0.8-0.10.3-1.9-1.61.31.6-1.1-1.11.10.30.8-0.5
Time in familiar zone, hab. session 12.01.93.3-1.7-0.40.5-1.6-0.81.11.3-1.8-1.81.81.31.70.3
Time in novel zone, hab. session 11.71.62.71.60.1-0.71.60.8-0.9-1.21.61.6-1.6-1.3-1.6-0.5
Total zone transitions, hab. session 11.11.63.8-1.10.30.3-2.0-1.31.31.9-1.5-1.51.50.31.2-0.6
Total locomotion distance, hab. session 10.91.33.7-1.10.00.3-1.6-1.01.21.9-1.3-1.31.30.11.1-0.9
Locomotion velocity, hab. session 10.81.13.8-0.80.10.3-1.7-1.21.21.9-1.0-1.01.0-0.10.9-1.0
Time in familiar zone, hab. session 20.50.62.9-0.21.01.20.1-0.30.4-0.1-0.2-0.20.21.30.21.7
Time in novel zone, hab. session 20.50.52.9-0.3-1.0-1.0-0.30.1-0.10.4-0.4-0.40.4-1.00.4-1.7
Total zone transitions, hab. session 20.30.41.2-0.31.10.7-1.0-0.50.50.6-0.5-0.50.50.30.4-0.0
Total locomotion distance, hab. session 20.30.30.6-0.40.70.6-0.8-0.40.60.8-0.6-0.60.60.30.50.1
Locomotion velocity, hab. session 20.10.10.4-0.10.70.5-0.30.00.20.3-0.3-0.30.30.20.20.2
Novel to familiar place preference ratio0.10.10.30.00.30.3-0.2-0.30.20.1-0.1-0.10.10.20.00.5
Novelty place preference0.20.20.6-0.20.50.5-0.6-0.20.30.3-0.4-0.40.40.40.20.8
Time in novel zone, NPP test0.20.20.4-0.40.30.3-0.7-0.10.20.2-0.5-0.50.50.40.40.6
Total zone transitions, NPP test0.50.71.5-1.00.10.4-1.0-0.40.51.2-1.1-1.11.10.41.1-0.6
Total locomotion distance, NPP test0.60.81.9-0.90.40.4-1.2-0.80.81.4-1.1-1.11.10.21.0-0.7
Locomotion velocity, NPP test0.70.92.5-0.81.10.9-1.3-0.90.91.6-0.9-0.90.90.40.9-0.1
Pavlov. Cond. lever latency0.40.51.20.50.60.31.10.5-0.3-0.90.80.8-0.80.1-0.60.6
Pavlov. Cond. magazine entry latency0.30.41.40.3-1.2-1.0-0.2-0.2-0.30.10.10.1-0.1-0.9-0.2-1.2
Pavlov. Cond. change in total contacts0.40.41.1-0.3-0.7-0.4-1.1-0.50.30.7-0.7-0.70.7-0.40.3-1.0
Pavlov. Cond. index score0.30.30.9-0.1-0.9-0.7-0.7-0.50.10.7-0.4-0.40.4-0.60.2-0.9
Pavlov. Cond. latency score0.30.31.20.0-1.0-0.9-0.7-0.3-0.20.5-0.3-0.30.3-0.70.0-1.1
Pavlov. Cond. lever contacts0.70.82.3-0.8-0.30.1-1.5-1.00.81.3-1.1-1.11.10.30.8-0.2
Pavlov. Cond. magazine entry number0.20.31.0-0.30.90.80.30.40.0-0.4-0.1-0.10.10.90.31.0
Pavlov. Cond. intertrial magazine entries0.20.30.5-0.50.10.4-0.7-0.20.50.4-0.7-0.70.70.40.50.5
Pavlov. Cond. lever-magazine prob. diff.0.30.31.0-0.1-0.9-0.7-0.6-0.70.20.7-0.4-0.40.4-0.60.1-1.0
Pavlov. Cond. response bias0.40.51.1-0.6-0.5-0.0-1.0-0.80.61.1-0.8-0.80.80.10.6-0.4
Bone: apparent density0.40.71.51.10.1-0.30.20.8-1.2-1.21.01.0-1.0-0.6-1.1-0.3
Bone surface2.74.88.22.5-1.0-1.61.52.4-2.9-2.72.42.4-2.4-2.0-2.5-0.9
Bone volume1.72.94.92.0-0.7-1.21.01.7-2.2-2.01.91.9-1.9-1.6-2.0-0.9
Bone: connectivity density0.91.43.41.3-0.1-0.41.21.3-1.6-1.91.31.3-1.3-0.5-1.3-0.1
Bone: cortical apparent density0.30.41.70.30.2-0.20.31.3-1.1-1.00.30.3-0.3-0.1-0.30.2
Bone: cortical area0.30.52.50.4-0.1-0.7-1.4-0.3-0.50.30.20.2-0.2-1.0-0.4-1.6
Bone: cortical porosity1.51.62.3-1.50.41.1-0.6-1.21.51.4-1.5-1.51.51.31.51.0
Bone: cortical porosity0.80.91.7-1.2-0.00.50.0-1.11.31.2-1.1-1.11.10.71.20.5
Bone: cortical thickness0.50.83.0-0.8-0.1-0.1-1.7-0.80.21.1-1.0-1.01.0-0.00.8-1.3
Bone: cortical thickness0.20.21.10.10.80.2-1.00.8-0.4-0.20.00.0-0.0-0.0-0.1-0.2
Bone: cortical tissue density0.30.31.70.30.3-0.10.41.3-1.1-1.00.20.2-0.2-0.0-0.30.3
Bone: elastic displacement0.40.41.4-0.30.80.9-1.2-0.30.60.5-0.5-0.50.50.70.30.9
Bone: elastic work1.82.46.9-0.82.12.0-2.6-1.31.51.5-1.1-1.11.11.40.81.7
Bone: endosteal estimation0.81.83.41.80.3-0.70.61.0-1.2-1.41.81.8-1.8-1.5-1.8-0.1
Bone: endosteal perimeter1.12.24.32.1-0.1-1.10.40.7-1.3-1.21.91.9-1.9-1.9-2.1-0.6
Bone: final force0.20.31.7-0.20.60.2-1.3-0.80.10.8-0.3-0.30.3-0.30.3-0.8
Bone: final moment0.20.31.8-0.20.4-0.1-1.3-0.5-0.10.7-0.4-0.40.4-0.50.3-0.9
Bone: marrow area0.91.93.51.90.3-0.70.61.0-1.3-1.41.81.8-1.8-1.5-1.9-0.1
Bone: maximum diameter1.01.94.01.5-1.1-1.7-0.00.7-1.3-0.91.31.3-1.3-2.0-1.5-2.0
Bone: maximum force0.30.52.8-0.11.30.7-1.7-0.90.50.8-0.3-0.30.30.00.20.1
Bone: maximum moment0.30.53.0-0.21.10.6-1.7-0.80.40.8-0.5-0.50.5-0.00.30.1
Bone: minimum diameter0.81.63.01.7-0.1-0.9-0.10.5-1.2-0.91.61.6-1.6-1.6-1.7-1.0
Bone: periosteal estimation0.71.43.31.6-0.1-1.1-0.30.4-1.1-0.71.31.3-1.3-1.8-1.5-1.3
Bone: periosteal perimeter0.30.51.60.90.7-0.2-1.3-0.5-0.20.30.60.6-0.6-1.0-0.9-0.5
Bone: post-yield work0.50.71.6-0.61.20.9-1.3-0.40.80.7-0.8-0.80.80.60.71.1
Bone: stiffness0.00.10.3-0.20.20.1-0.5-0.40.10.3-0.2-0.20.2-0.10.2-0.1
Bone: tissue strength0.40.40.9-0.9-0.10.30.0-0.40.50.5-0.9-0.90.90.70.90.3
Bone: trabecular number0.91.43.81.2-0.4-0.80.81.4-2.0-1.51.21.2-1.2-0.9-1.2-0.8
Bone: trabecular spacing0.81.12.2-1.5-0.80.2-0.2-0.70.90.9-1.4-1.41.40.91.5-0.1
Bone: trabecular thickness3.34.06.22.5-0.3-1.41.51.8-2.2-2.22.42.4-2.4-2.0-2.5-0.8
Bone: trabecular tissue density1.52.18.4-0.1-2.9-2.41.10.7-0.6-0.2-0.0-0.00.0-1.70.1-2.8
Breakpoint value in progressive ratio session0.60.61.80.8-1.3-0.90.40.5-0.5-0.50.80.8-0.8-0.9-0.8-0.8
Distance traveled before self-admin1.31.44.5-1.30.81.0-2.1-0.50.81.1-1.4-1.41.41.01.30.3
Distance traveled after self-admin0.40.42.0-0.20.10.1-0.4-1.41.01.1-0.5-0.50.5-0.20.2-0.8
Delta time in closed arm before/after self-admin0.50.51.3-1.2-0.00.7-0.20.30.40.3-0.6-0.60.61.11.20.5
Delta time in open arm before/after self-admin0.70.72.90.3-1.7-1.40.9-0.2-0.2-0.3-0.0-0.00.0-1.0-0.3-1.3
Diff in mean of infusions in LGA sessions0.20.20.50.40.50.3-0.3-0.40.40.10.70.7-0.7-0.1-0.4-0.2
Extinction: sum of active levers before priming0.50.51.70.7-0.4-0.80.20.1-0.4-0.50.60.6-0.6-0.9-0.7-1.3
Active lever presses in extinction session 60.20.21.10.2-0.5-0.10.1-0.70.50.60.20.2-0.2-0.1-0.2-1.1
Delta distance traveled before/after self-admin0.50.51.90.60.1-0.31.4-1.10.60.30.60.6-0.6-0.6-0.6-0.6
Delta ambulatory time before/after self-admin0.70.82.41.10.3-0.21.5-1.20.50.11.01.0-1.0-0.7-1.1-0.4
Time in closed arm before self-admin0.20.21.90.41.40.50.1-0.1-0.2-0.40.20.2-0.20.1-0.40.2
Time in closed arm after self-admin1.11.22.2-1.31.51.3-0.6-1.01.10.9-1.0-1.01.01.21.30.3
Time in open arm before self-admin0.10.21.1-0.1-0.10.2-0.3-0.60.61.00.10.1-0.10.10.10.1
Time in open arm after self-admin0.40.41.70.3-1.3-0.90.1-0.80.60.60.20.2-0.2-0.8-0.3-0.7
Sum of active levers in priming session hrs 5-67.77.68.82.8-2.8-2.92.72.6-2.8-2.83.03.0-3.0-2.7-2.8-1.8
Time to tail flick, vehicle, before self-admin0.10.10.4-0.30.60.00.20.5-0.6-0.2-0.1-0.10.10.30.3-0.2
Time to tail flick, vehicle, after self-admin1.11.22.71.30.7-0.31.60.5-0.9-1.01.51.5-1.5-0.6-1.30.3
Time to tail flick, test, before self-admin5.65.58.82.2-2.8-3.02.11.4-1.8-1.82.42.4-2.4-3.0-2.2-2.5
Time to tail flick, test, after self-admin0.40.42.4-0.2-0.3-0.4-0.1-1.20.50.8-0.2-0.20.2-0.60.2-1.5
Delta time to tail flick, vehicle, before/after SA0.80.81.41.2-0.6-0.60.90.4-0.5-0.71.11.1-1.1-1.0-1.2-0.4
Delta time to tail flick, test, before/after SA5.34.75.8-2.31.92.4-1.7-2.42.22.4-2.3-2.32.32.32.31.2
Ambulatory time before self-admin1.71.84.3-1.60.20.8-2.1-0.70.91.4-1.8-1.81.81.11.6-0.0
Ambulatory time after self-admin0.80.92.2-0.60.50.5-1.1-1.51.11.5-0.9-0.90.90.10.6-0.9
Total heroin consumption0.00.00.4-0.0-0.40.1-0.0-0.00.20.20.00.0-0.00.20.00.6
Area under the delay curve3.03.27.51.2-2.7-2.21.82.3-2.1-2.11.31.3-1.3-1.4-1.2-1.6
Delay disc. indifference point, 0s delay3.23.59.11.4-1.9-2.52.01.5-1.7-1.61.31.3-1.3-2.4-1.4-3.0
Delay disc. indifference point, 16s delay1.81.94.01.2-1.4-1.21.31.8-1.5-2.01.41.4-1.4-0.8-1.2-0.3
Delay disc. indifference point, 2s delay1.71.94.90.7-2.2-1.91.71.3-1.2-1.30.80.8-0.8-1.3-0.7-1.9
Delay disc. indifference point, 24s delay0.20.21.1-0.4-1.0-0.30.60.6-0.4-0.3-0.3-0.30.30.40.40.2
Delay disc. indifference point, 4s delay1.71.86.40.4-2.5-2.10.91.4-1.0-1.10.40.4-0.4-1.4-0.4-2.1
Delay disc. indifference point, 8s delay3.73.86.91.7-2.6-2.32.11.9-2.1-2.11.71.7-1.7-1.7-1.7-1.7
Delay discount exponential model param2.93.18.0-1.12.82.2-1.8-2.32.12.1-1.2-1.21.21.31.11.5
Delay discount hyperbolic model param3.13.38.7-1.23.02.3-1.9-2.32.02.1-1.2-1.21.21.41.21.7
Fecal boli incidents, locomotor time 10.40.41.7-0.2-1.2-1.00.40.3-0.6-0.10.00.0-0.0-0.70.2-1.3
Change in fecal boli incidents, locomotor task0.80.81.71.3-0.6-0.61.30.4-0.3-0.81.01.0-1.0-0.6-1.30.1
Time >=10cm from walls, locomotor time 10.00.00.20.1-0.2-0.4-0.20.00.10.1-0.0-0.00.0-0.4-0.1-0.4
Bouts of movement, locomotor time 10.20.31.2-0.7-1.1-0.40.00.30.20.4-0.5-0.50.50.10.7-0.5
Total resting periods, locomotor time 10.20.20.4-0.6-0.6-0.2-0.20.30.20.4-0.4-0.40.40.00.6-0.5
Rest time, locomotor task time 11.41.65.80.4-2.1-1.71.31.1-0.9-0.90.60.6-0.6-1.1-0.4-2.4
Distance moved, locomotor task time 10.90.92.7-0.41.20.8-1.1-1.71.41.5-0.5-0.50.50.40.41.0
Vertical activity count, locomotor time 11.01.12.7-0.11.31.1-1.1-1.61.41.3-0.4-0.40.40.70.11.6
Time >=10cm from walls, locomotor time 20.10.10.30.10.20.3-0.6-0.00.30.10.10.1-0.10.0-0.10.3
Bouts of movement, locomotor time 20.40.51.0-1.0-0.6-0.1-0.40.2-0.00.3-1.0-1.01.00.71.0-0.0
Total resting periods, locomotor time 20.40.51.0-1.0-0.40.1-0.50.10.10.3-1.0-1.01.00.81.00.1
Rest time, locomotor task time 20.60.72.40.1-1.6-0.90.71.5-0.8-0.90.00.0-0.0-0.3-0.1-1.2
Distance moved, locomotor task time 20.30.31.80.20.90.1-0.2-1.30.80.80.20.2-0.2-0.5-0.20.0
Vertical activity count, locomotor time 20.70.71.71.30.7-0.30.4-0.6-0.0-0.21.21.2-1.2-0.9-1.30.0
Weight adjusted by age0.50.61.00.7-0.8-0.70.80.5-0.9-0.71.01.0-1.0-0.5-0.7-0.6
Seeking ratio, delayed vs. immediate footshock0.10.10.3-0.4-0.20.10.50.1-0.0-0.0-0.0-0.00.00.20.30.6
Locomotion in novel chamber0.60.85.2-0.0-2.3-1.10.60.2-0.10.1-0.2-0.20.2-0.50.1-1.6
Locomotion in novel chamber post-restriction3.84.610.52.3-2.2-2.43.20.8-1.6-1.72.22.2-2.2-2.1-2.3-1.7
Progressive ratio0.91.12.50.91.60.4-0.51.4-1.2-1.01.01.0-1.0-0.3-0.91.4
Food seeking constrained by brief footshock1.21.43.31.71.80.30.70.0-0.5-0.51.51.5-1.5-0.7-1.61.2
Seeking ratio, punishment vs. effort0.20.31.30.2-0.4-0.30.8-1.20.60.50.00.0-0.0-0.3-0.2-0.6
Run reversals in cocaine runway, females0.50.51.11.01.1-0.10.3-0.80.10.10.70.7-0.7-0.7-1.0-0.4
Run reversals in cocaine runway, males0.50.41.1-1.00.10.00.10.30.10.2-1.0-1.01.00.31.0-0.3
Latency to leave start box in cocaine runway3.43.77.4-1.32.71.9-2.3-2.72.42.2-1.5-1.51.51.11.31.6
Latency to leave start box in cocaine runway, F1.21.34.3-0.62.11.0-1.3-1.71.31.2-0.7-0.70.70.40.61.0
Latency to leave start box in cocaine runway, M3.73.56.1-1.71.61.6-2.3-2.52.42.4-1.9-1.91.91.21.70.8
Cd content in liver1.11.22.11.4-0.7-1.20.70.2-0.6-1.01.31.3-1.3-1.3-1.4-1.2
Co content in liver0.91.13.4-0.80.50.8-0.7-1.71.81.3-0.8-0.80.80.80.80.5
Cu content in liver0.50.61.10.7-1.0-1.00.20.4-0.7-0.60.70.7-0.7-0.9-0.7-1.0
Fe content in liver0.10.20.6-0.5-0.8-0.0-0.20.00.00.4-0.5-0.50.50.30.6-0.4
K content in liver0.90.94.30.12.01.4-0.70.10.1-0.20.10.1-0.10.9-0.12.1
Mg content in liver0.10.10.6-0.10.40.3-0.20.5-0.5-0.4-0.1-0.10.10.30.10.8
Mn content in liver0.20.21.3-0.1-0.00.11.10.4-0.3-0.8-0.0-0.00.00.20.10.3
Na content in liver0.50.51.7-0.70.70.5-1.3-0.60.30.8-0.8-0.80.80.40.70.5
Rb content in liver1.82.24.01.8-0.4-0.91.01.3-1.8-2.01.81.8-1.8-1.0-1.90.2
Se content in liver1.01.34.4-0.0-2.1-1.40.51.8-1.5-1.1-0.0-0.00.0-0.60.1-1.6
Sr content in liver0.30.31.6-0.10.50.1-1.3-0.90.70.6-0.2-0.20.2-0.10.1-0.1
Zn content in liver3.03.35.81.4-2.0-2.41.82.1-2.2-1.71.41.4-1.4-2.1-1.4-1.8