Hub : Genes

Actn3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000019745 0.2 0.11 3.6e-09 0.15 0.15 0.14 0.16 2.4e-08 2.3e-08 5.4e-08 7.5e-09
2 Brain gene expression ENSRNOG00000019745 0.24 0.08 0.0e+00 0.29 0.31 0.31 0.32 5.6e-27 1.8e-29 2.2e-29 2.9e-30
3 Brain mRNA stability ENSRNOG00000019745 0.05 0.04 5.4e-04 0.04 0.03 0.05 0 5.2e-05 3.6e-04 4.0e-05 1.8e-01
4 IL gene expression ENSRNOG00000019745 0.13 0.1 9.0e-03 0.07 0.05 0.07 0.04 8.1e-03 3.0e-02 1.1e-02 3.3e-02
5 LHb gene expression ENSRNOG00000019745 0.23 0.13 4.5e-04 0.14 0.11 0.12 0.15 3.0e-04 1.6e-03 9.0e-04 2.1e-04
6 Liver gene expression ENSRNOG00000019745 0.3 0.13 0.0e+00 0.18 0.18 0.17 0.18 8.3e-20 9.8e-20 9.7e-19 1.7e-19
7 NAcc gene expression ENSRNOG00000019745 0.17 0.08 2.7e-14 0.15 0.18 0.18 0.18 2.3e-11 1.5e-13 1.7e-13 1.3e-13
8 NAcc mRNA stability ENSRNOG00000019745 0.06 0.04 1.3e-04 0.05 0.04 0.03 0.04 2.2e-04 6.3e-04 2.7e-03 6.1e-04
9 PL gene expression ENSRNOG00000019745 0.18 0.1 5.0e-14 0.11 0.17 0.19 0.17 1.5e-08 3.2e-13 4.0e-14 7.6e-13

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail0.72.47.0-0.90.41.12.6-0.7-0.72.10.92.5
BMI without tail0.30.72.2-0.30.40.31.3-0.4-0.11.20.31.5
Body weight2.08.317.82.02.9-1.54.21.92.04.0-2.03.8
Epididymis fat weight2.66.08.0-2.4-2.52.3-2.8-2.2-2.1-2.82.3-2.6
Glucose3.45.26.9-2.4-2.52.2-1.8-2.6-2.5-2.12.4-2.0
Heart weight2.73.95.3-1.9-1.71.9-2.1-2.1-1.6-2.31.8-2.3
Left kidney weight0.30.92.9-0.5-0.60.4-1.3-0.6-0.3-1.40.3-1.7
Right kidney weight0.10.31.30.00.10.5-0.40.70.2-0.9-0.3-1.1
Tail length1.95.67.72.82.5-2.61.32.32.72.1-2.81.7
Length with tail2.810.412.33.33.5-3.03.23.03.33.4-3.32.8
Length without tail2.04.57.31.82.2-1.52.71.91.72.6-1.92.4
Liver weight, left0.00.10.30.1-0.1-0.3-0.60.10.3-0.20.00.0
Liver weight, right0.10.10.20.2-0.0-0.4-0.4-0.00.30.2-0.30.5
Parametrial fat weight3.36.47.4-2.7-2.42.5-2.4-2.5-2.2-2.62.7-2.6
Retroperitoneal fat weight4.615.320.7-3.5-4.03.3-4.6-3.6-3.4-4.53.6-4.3
Intraocular pressure0.50.73.0-0.2-0.30.6-1.00.10.2-1.40.2-1.7
Extensor digitorum longus weight5.221.034.73.94.9-2.95.93.83.95.7-3.85.5
Soleus weight2.26.314.7-1.6-2.70.4-3.8-2.2-1.8-3.11.6-3.4
Tibialis anterior weight9.934.042.55.46.4-4.96.55.65.56.5-5.36.1
Tibia length0.82.23.81.41.6-1.31.72.01.41.4-1.50.8
Number of licking bursts0.10.10.40.20.40.20.70.3-0.00.5-0.10.2
Food consumed during 24 hour testing period0.20.20.60.40.2-0.60.30.50.2-0.0-0.2-0.8
Times rat made contact with spout0.20.20.70.20.40.20.8-0.1-0.00.8-0.10.7
Mean time between licks in bursts0.71.02.41.10.6-0.80.70.60.71.2-1.01.6
Mean num. licks in bursts0.10.20.5-0.4-0.50.3-0.4-0.7-0.3-0.30.4-0.0
Std. dev. time between licks in bursts0.60.71.61.00.7-1.3-0.40.51.20.5-1.00.8
Water consumed over 24 hours0.40.41.20.50.8-0.11.10.30.40.9-0.40.6
Indifference point 0 sec0.30.41.0-0.6-0.81.0-0.4-0.5-0.6-0.50.7-0.5
Indifference point AUC2.42.84.31.32.0-1.12.11.61.61.9-1.32.0
Indifference point function ln k3.85.413.0-1.5-2.70.8-3.6-2.1-1.8-2.91.5-2.7
Indifference point function log k3.85.413.0-1.5-2.70.8-3.6-2.1-1.8-2.91.5-2.7
Delay discounting total patch changes 0 sec0.00.00.1-0.0-0.30.3-0.3-0.10.1-0.20.1-0.1
Delay discounting total patch changes 12 sec2.33.06.01.11.9-0.52.41.41.52.3-1.02.3
Delay discounting total patch changes 18 sec0.20.20.7-0.30.40.70.80.10.40.40.10.5
Delay discounting total patch changes 24 sec1.92.43.31.31.6-0.91.71.51.61.8-1.41.7
Delay discounting total patch changes 6 sec0.40.61.80.30.70.11.30.30.51.2-0.21.2
Delay discounting time to switch 0 sec0.50.73.9-0.30.30.52.0-0.2-0.41.10.30.8
Delay discounting water rate 0 sec1.32.18.3-0.4-1.10.2-2.9-0.3-0.1-2.20.3-2.1
Delay discounting water rate 12 sec2.43.615.5-0.5-1.60.1-3.9-1.0-0.6-2.60.5-2.4
Delay discounting water rate 18 sec1.11.45.2-0.5-1.1-0.2-2.3-1.0-0.7-1.40.5-1.6
Delay discounting water rate 24 sec1.31.87.2-0.3-0.9-0.1-2.7-0.6-0.1-1.90.3-2.0
Delay discounting water rate 6 sec0.81.15.20.2-0.7-0.3-2.3-0.50.2-1.3-0.2-1.5
Locomotor activity0.30.52.40.3-0.5-0.0-1.5-0.10.1-0.8-0.3-0.8
Locomotor testing distance0.40.63.30.3-0.6-0.2-1.8-0.3-0.0-0.9-0.3-0.8
Locomotor testing rearing0.91.43.3-1.0-1.10.9-1.8-1.2-0.9-1.30.9-1.1
Light reinforcement 10.10.10.4-0.1-0.40.3-0.6-0.3-0.1-0.40.1-0.2
Light reinforcement 20.71.02.2-0.7-0.90.7-0.9-0.4-1.2-1.50.7-1.4
Reaction time number correct0.60.91.31.21.1-0.40.61.11.20.8-1.10.8
Reaction time mean minus median1.31.85.60.71.70.02.41.50.71.5-0.81.2
Reaction time mean minus median AUC1.51.93.71.21.9-0.41.81.61.21.3-1.21.1
Reaction time num false alarms0.40.61.01.00.5-1.0-0.60.31.00.4-1.00.5
Reaction time num false alarms AUC0.91.31.91.31.1-1.30.30.81.41.0-1.41.1
Reaction time trials correct on left0.60.91.31.21.1-0.40.61.11.20.8-1.10.8
Reaction time trials on left0.81.21.71.31.2-0.50.71.31.31.0-1.20.9
Reaction time mean0.00.10.1-0.20.00.30.20.4-0.2-0.20.1-0.2
Reaction time mean AUC0.10.10.2-0.4-0.10.50.10.2-0.3-0.40.3-0.4
Median of all reaction times0.20.20.4-0.5-0.50.4-0.3-0.1-0.5-0.60.4-0.5
Reaction time omissions1.41.93.11.21.8-0.51.71.61.31.4-1.31.3
Reaction time false alarm rate0.20.31.00.60.3-1.0-0.30.10.60.3-0.70.4
Reaction time premature initiation rate2.63.55.91.81.9-1.41.81.61.62.2-1.92.4
Reaction time premature initiations4.66.58.82.62.7-1.82.42.52.42.8-2.73.0
Std. dev. reaction times0.40.51.70.30.90.21.31.00.40.6-0.40.4
Reaction time trials completed0.81.21.71.31.2-0.50.71.31.31.0-1.20.9
Reaction time trials AUC0.60.81.31.11.0-0.40.51.01.10.8-1.00.7
Social response proportion0.20.21.30.00.10.21.10.2-0.20.60.00.4
Social responses0.20.30.50.50.5-0.60.70.50.60.6-0.50.5
Social time0.50.71.40.90.8-1.20.70.70.80.9-0.80.7
Conditioned locomotion2.42.84.11.82.0-1.51.51.21.91.9-1.71.3
Cocaine response after cond. corrected0.50.51.5-0.3-0.60.5-1.2-0.9-0.3-0.80.5-0.9
Cocaine response after cond. not corrected0.50.61.1-0.6-0.80.6-1.0-0.9-0.6-0.80.6-0.7
Cocaine response before conditioning0.20.21.0-0.10.0-0.11.00.7-0.20.40.00.6
Saline control response2.12.85.61.21.7-1.12.31.11.02.3-1.22.4
Condit. Reinf. active minus inactive responses1.11.42.5-1.3-1.11.6-0.3-0.9-1.5-0.91.3-1.0
Condit. Reinf. active-inactive response ratio1.71.82.6-1.4-1.41.4-0.8-0.9-1.6-1.41.4-1.6
Condit. Reinf. active responses0.91.23.1-1.3-0.91.80.2-1.0-1.5-0.41.3-0.4
Condit. Reinf. inactive responses0.40.41.1-0.7-0.11.00.7-0.7-0.50.40.70.8
Condit. Reinf. lever presses0.71.04.20.20.80.12.10.80.11.2-0.21.2
Condit. Reinf. lever reinforcers received0.60.82.2-1.1-0.61.50.6-0.7-1.3-0.01.1-0.1
Pavlov. Cond. lever latency0.10.21.0-0.0-0.40.1-1.0-0.4-0.0-0.40.0-0.3
Pavlov. Cond. magazine entry latency1.41.65.70.61.1-0.22.40.70.31.8-0.51.8
Pavlov. Cond. change in total contacts0.40.63.4-0.30.30.61.80.5-0.50.80.30.5
Pavlov. Cond. index score0.71.04.40.30.8-0.22.10.70.01.3-0.31.1
Pavlov. Cond. latency score0.60.83.60.30.7-0.21.90.70.01.2-0.30.9
Pavlov. Cond. lever contacts0.20.31.00.40.5-0.61.00.80.30.5-0.40.4
Pavlov. Cond. magazine entry number2.43.010.3-0.9-1.60.4-3.2-1.2-0.5-2.40.8-2.2
Pavlov. Cond. intertrial magazine entries0.70.91.9-0.8-0.90.6-1.4-0.7-0.6-1.30.6-1.2
Pavlov. Cond. lever-magazine prob. diff.0.91.25.20.40.9-0.32.30.80.21.5-0.41.3
Pavlov. Cond. response bias0.60.93.30.40.8-0.31.80.90.21.1-0.31.1
Conditioned reinforcement - actives0.10.10.4-0.1-0.30.1-0.50.2-0.1-0.60.2-0.5
Conditioned reinforcement - inactives4.45.08.7-2.0-2.31.7-2.5-1.5-1.9-2.92.0-2.9
Conditioned locomotion4.14.911.0-1.5-2.30.9-3.3-1.4-1.4-3.01.5-3.0
Intermittent access intake day 1-15 change0.20.21.10.10.0-0.2-0.50.40.2-0.60.0-1.0
Intermittent access intake escalation0.20.21.0-0.3-0.30.1-0.50.0-0.1-0.60.2-1.0
Intermittent access intake escalation 20.20.20.40.40.1-0.4-0.30.60.4-0.3-0.4-0.7
Intermitt. access day 1 inactive lever presses2.32.44.4-1.4-1.51.1-1.3-1.3-1.5-2.11.4-2.1
Intermitt. access day 15 inactive lever presses1.92.14.4-1.3-1.51.2-1.2-1.0-1.3-1.81.4-2.1
Intermitt. access escalation Index3.73.34.9-1.9-2.11.4-2.2-2.1-1.6-1.81.9-1.3
Intermittent access day 1 total infusions8.910.112.3-3.5-3.43.2-2.3-3.4-3.5-3.03.4-2.6
Intermittent access day 15 total infusions7.58.410.9-2.9-3.02.5-2.7-2.6-2.8-3.32.9-3.3
Intermittent access terminal intake (last 3 days)6.36.98.8-2.7-2.62.4-2.2-2.4-2.6-3.02.7-2.9
Intermittent access total infusions6.57.28.9-3.0-2.82.7-1.9-2.7-2.9-2.72.9-2.5
Intermittent access day 1 locomotion6.36.48.5-2.9-2.82.6-1.5-2.9-2.8-2.32.8-1.8
Intermittent access day 15 total locomotion5.25.56.6-2.5-2.42.2-2.1-2.1-2.4-2.52.4-2.6
Intermittent access total locomotion9.710.913.5-3.7-3.63.3-2.3-3.3-3.6-3.23.6-3.0
Intermittent access standard deviation0.50.51.6-0.5-0.40.3-0.9-0.5-0.4-1.00.4-1.3
Cocaine induced anxiety0.00.10.10.20.3-0.20.20.30.30.0-0.3-0.1
Post-drug Anxiety1.71.92.51.41.5-1.21.51.61.41.1-1.51.0
Baseline Anxiety2.42.63.11.61.6-1.31.71.81.61.6-1.61.7
Lifetime Intake5.86.58.4-2.9-2.62.6-1.7-2.7-2.8-2.52.8-2.2
Incentive Sensitization - Responses0.70.71.1-0.9-0.71.0-0.4-0.7-1.0-0.81.0-0.9
Incentive Sensitization - Breakpoint0.90.91.2-1.0-0.81.0-0.6-0.7-1.0-1.01.1-1.1
Progressive ratio test 1 active lever presses2.32.43.5-1.6-1.71.4-1.5-1.3-1.5-1.91.4-1.6
Progressive ratio test 1 breakpoint1.81.93.1-1.3-1.51.2-1.3-1.1-1.3-1.81.2-1.5
Progressive ratio test 1 inactive lever presses1.21.31.7-1.1-1.31.0-1.0-1.2-1.1-1.21.3-1.1
Progressive ratio test 2 active lever presses4.04.25.7-2.1-2.11.9-1.8-1.7-2.1-2.42.1-2.3
Progressive ratio test 2 breakpoint3.74.26.6-1.8-2.01.6-2.2-1.6-1.9-2.61.9-2.5
Progressive ratio test 2 inactive lever presses8.910.312.2-3.1-3.52.9-3.0-3.0-3.1-3.53.2-3.4
Total sessions with >9 infusions2.02.23.0-1.7-1.41.4-1.1-1.7-1.5-1.51.5-1.3
Short access day 1 total inactive lever presses3.53.95.7-1.9-2.11.7-2.1-1.9-1.9-2.41.9-1.9
Short access day 10 total inactive lever presses1.71.83.4-0.9-1.30.6-1.7-1.4-1.0-1.90.9-1.8
Short access day 1 total infusions5.15.47.0-2.6-2.32.4-1.7-2.5-2.5-2.32.6-1.7
Short access day 10 total infusions5.05.58.6-2.9-2.42.8-0.9-2.7-2.8-1.52.8-1.2
Short access total infusions2.83.14.6-2.2-1.82.0-0.9-2.0-2.0-1.52.0-1.0
Short access day 1 locomotion4.04.25.6-2.3-2.22.2-1.3-2.2-2.3-1.82.4-1.6
Short access day 10 total locomotion3.13.45.0-2.2-2.01.9-1.1-2.2-2.1-1.32.1-1.3
Short access total locomotion2.82.94.1-2.0-1.91.8-0.9-1.9-2.0-1.31.9-1.0
Compulsive drug intake4.24.25.42.21.9-2.01.51.62.12.3-2.32.3
One hour access (0.3 mA shock)7.58.713.3-2.6-3.12.2-3.0-2.7-2.8-3.52.7-3.6
One hour access (shock baseline)8.49.714.9-3.0-3.12.6-2.8-2.5-3.0-3.73.1-3.9
Number of responses in last shaping day0.30.41.2-0.4-0.50.2-1.0-0.3-0.3-1.10.3-0.5
Context. condit. distance diff. score1.31.53.0-1.1-1.40.8-1.7-1.1-0.9-1.61.0-1.3
Locomotion velocity, session 10.30.30.60.80.3-0.70.00.50.40.4-0.80.5
Locomotion distance, session 10.30.40.7-0.4-0.20.60.8-0.7-0.80.80.30.8
Locomotion velocity, session 21.51.73.70.91.3-0.81.90.90.81.9-0.91.8
Locomotion distance, session 20.40.51.60.20.3-0.21.1-0.4-0.11.3-0.31.0
Locomotion velocity, session 30.30.40.8-0.7-0.90.6-0.3-0.8-0.7-0.30.60.0
Locomotion distance, session 30.00.00.1-0.2-0.30.1-0.1-0.2-0.1-0.10.1-0.0
Stereotopy head waving bouts, day 30.80.92.0-1.0-0.90.7-0.9-1.4-0.9-0.81.0-0.6
Stereotopy head waving duration, day 31.21.42.1-1.2-1.21.0-1.1-1.4-1.2-1.21.3-1.1
Locomotion velocity, session 70.80.91.6-1.2-1.11.0-0.5-1.3-0.9-0.61.1-0.5
Locomotion distance, session 70.00.10.2-0.1-0.20.1-0.0-0.50.00.20.10.4
Stereotopy head waving bouts, day 71.21.32.2-1.4-0.91.5-0.4-1.0-1.2-1.11.4-1.0
Stereotopy head waving duration, day 70.40.51.2-0.80.01.11.1-0.3-0.60.20.90.2
Locomotion velocity, session 81.21.52.31.21.2-1.01.11.01.11.4-1.21.5
Locomotion distance, session 80.30.40.7-0.6-0.70.6-0.6-0.8-0.8-0.40.5-0.5
Degree of sensitization distance0.10.10.3-0.3-0.10.20.0-0.5-0.20.10.30.2
Degree of sensitization stereotypy0.30.30.9-0.70.11.00.70.0-0.3-0.10.7-0.0
Condit. Reinf. active minus inactive responses0.10.10.50.10.10.20.7-0.1-0.40.40.00.3
Condit. Reinf. active-inactive response ratio0.10.10.3-0.1-0.10.40.4-0.1-0.50.00.2-0.1
Condit. Reinf. active responses0.10.10.30.10.20.10.6-0.1-0.30.3-0.00.1
Condit. Reinf. inactive responses0.00.00.1-0.2-0.10.20.0-0.3-0.2-0.10.2-0.2
Incentive salience index mean0.10.20.70.10.30.10.9-0.1-0.40.60.00.5
Condit. Reinf. lever presses0.20.30.80.50.6-0.20.90.40.10.6-0.40.4
Time in familiar zone, hab. session 10.60.61.2-0.8-1.10.9-0.4-0.5-1.0-0.70.8-0.4
Time in novel zone, hab. session 10.30.30.90.60.4-0.9-0.5-0.00.70.1-0.50.0
Total zone transitions, hab. session 10.40.61.50.50.7-0.31.20.50.31.2-0.71.0
Total locomotion distance, hab. session 10.30.40.6-0.6-0.60.3-0.7-0.7-0.7-0.50.5-0.8
Locomotion velocity, hab. session 10.00.10.2-0.2-0.10.1-0.2-0.4-0.4-0.00.1-0.3
Time in familiar zone, hab. session 20.60.61.20.90.7-1.10.00.51.00.6-0.90.7
Time in novel zone, hab. session 20.50.51.2-0.9-0.71.10.1-0.7-0.9-0.30.8-0.2
Total zone transitions, hab. session 21.01.22.8-1.1-0.31.71.2-1.2-1.20.91.00.9
Total locomotion distance, hab. session 20.81.02.2-1.2-0.71.3-0.2-1.5-1.3-0.21.2-0.4
Locomotion velocity, hab. session 21.01.42.4-1.4-1.01.5-0.4-1.6-1.5-0.51.3-0.7
Novel to familiar place preference ratio0.20.20.9-0.40.00.61.00.2-0.40.20.40.2
Novelty place preference0.30.30.6-0.7-0.30.80.5-0.1-0.7-0.10.7-0.1
Time in novel zone, NPP test0.20.30.5-0.7-0.40.70.4-0.2-0.7-0.20.7-0.1
Total zone transitions, NPP test0.71.13.20.40.90.11.80.40.01.6-0.51.5
Total locomotion distance, NPP test0.10.10.3-0.2-0.10.20.1-0.4-0.50.30.20.0
Locomotion velocity, NPP test0.00.10.2-0.10.00.20.2-0.3-0.40.40.10.0
Pavlov. Cond. lever latency0.10.10.3-0.0-0.2-0.1-0.5-0.1-0.0-0.30.1-0.4
Pavlov. Cond. magazine entry latency0.60.72.4-1.0-0.61.50.3-0.7-1.1-0.21.0-0.3
Pavlov. Cond. change in total contacts0.40.41.3-0.7-0.41.20.3-0.1-0.9-0.50.7-0.5
Pavlov. Cond. index score0.00.10.2-0.10.10.50.40.3-0.3-0.00.1-0.0
Pavlov. Cond. latency score0.10.10.3-0.2-0.10.60.2-0.0-0.4-0.10.2-0.1
Pavlov. Cond. lever contacts0.00.00.00.00.10.20.20.0-0.10.0-0.00.1
Pavlov. Cond. magazine entry number0.10.10.4-0.1-0.3-0.3-0.5-0.60.1-0.10.10.1
Pavlov. Cond. intertrial magazine entries0.10.10.3-0.10.0-0.1-0.50.20.1-0.50.0-0.5
Pavlov. Cond. lever-magazine prob. diff.0.10.10.40.00.20.40.60.3-0.20.20.00.2
Pavlov. Cond. response bias0.00.10.20.10.20.40.40.4-0.1-0.0-0.0-0.1
Bone: apparent density0.91.52.9-1.5-0.71.70.8-1.4-1.60.11.60.2
Bone surface0.91.67.5-0.40.61.12.70.2-0.51.60.41.6
Bone volume0.61.02.5-1.1-0.21.51.6-0.5-1.20.51.10.5
Bone: connectivity density0.81.23.6-0.80.21.41.9-0.7-0.81.20.81.2
Bone: cortical apparent density0.40.50.80.70.9-0.50.50.60.90.7-0.70.5
Bone: cortical area0.81.21.81.01.2-1.01.21.31.11.0-1.00.9
Bone: cortical porosity0.20.20.7-0.5-0.30.40.3-0.8-0.60.10.60.2
Bone: cortical porosity0.20.20.5-0.10.3-0.00.7-0.4-0.10.70.10.7
Bone: cortical thickness5.28.610.53.03.2-2.82.63.03.22.9-3.02.7
Bone: cortical thickness2.73.24.82.01.8-1.91.11.62.21.6-2.01.6
Bone: cortical tissue density0.50.61.00.81.0-0.60.60.71.00.8-0.80.6
Bone: elastic displacement0.50.61.11.00.5-1.0-0.90.41.1-0.0-1.0-0.2
Bone: elastic work2.33.14.41.91.9-1.71.01.52.11.7-1.91.6
Bone: endosteal estimation2.04.46.0-2.2-2.32.0-1.5-2.3-2.4-1.82.2-1.8
Bone: endosteal perimeter3.57.211.0-2.9-3.12.9-1.6-2.5-3.3-2.32.8-2.3
Bone: final force1.32.24.81.11.5-1.02.21.21.01.9-1.11.8
Bone: final moment1.21.94.31.01.3-0.92.11.10.91.8-1.01.7
Bone: marrow area2.14.56.1-2.3-2.42.0-1.6-2.4-2.5-1.82.2-1.8
Bone: maximum diameter0.00.10.40.1-0.0-0.00.50.6-0.1-0.0-0.1-0.2
Bone: maximum force0.81.46.20.20.90.32.50.50.01.7-0.21.5
Bone: maximum moment0.71.25.30.20.80.32.30.5-0.01.6-0.21.5
Bone: minimum diameter2.44.56.1-2.4-2.22.2-1.2-2.5-2.4-1.72.5-1.6
Bone: periosteal estimation0.10.30.4-0.6-0.50.5-0.1-0.4-0.6-0.50.6-0.5
Bone: periosteal perimeter0.20.30.7-0.7-0.50.80.3-0.3-0.8-0.20.7-0.2
Bone: post-yield work4.46.013.0-2.9-2.23.60.5-2.3-3.3-0.92.9-1.0
Bone: stiffness0.60.94.1-0.30.50.72.00.2-0.41.20.31.2
Bone: tissue strength0.20.20.5-0.4-0.40.70.2-0.4-0.7-0.10.4-0.3
Bone: trabecular number0.81.22.8-1.4-0.41.71.0-1.0-1.30.11.40.0
Bone: trabecular spacing0.10.10.40.4-0.0-0.4-0.70.10.3-0.1-0.4-0.0
Bone: trabecular thickness1.51.82.8-1.6-1.41.5-0.5-1.5-1.7-1.01.6-0.9
Bone: trabecular tissue density1.82.55.8-0.8-1.60.3-2.4-1.1-0.9-2.10.9-2.4
Breakpoint value in progressive ratio session2.02.34.41.11.6-0.92.11.61.11.7-1.21.7
Distance traveled before self-admin0.10.10.20.20.3-0.10.50.50.10.4-0.10.3
Distance traveled after self-admin0.00.00.10.10.00.10.20.4-0.10.10.1-0.0
Delta time in closed arm before/after self-admin0.60.61.30.71.0-0.80.20.31.10.9-0.70.9
Delta time in open arm before/after self-admin0.10.10.2-0.00.10.20.10.40.0-0.50.0-0.3
Diff in mean of infusions in LGA sessions0.50.51.20.70.8-0.30.81.10.90.5-0.70.5
Extinction: sum of active levers before priming1.81.94.70.71.4-0.42.21.20.81.8-0.81.8
Active lever presses in extinction session 62.72.64.21.71.9-1.51.52.01.61.4-1.51.4
Delta distance traveled before/after self-admin0.00.00.00.1-0.20.0-0.20.00.1-0.10.0-0.0
Delta ambulatory time before/after self-admin0.00.00.10.2-0.0-0.2-0.10.10.20.2-0.10.2
Time in closed arm before self-admin0.20.20.6-0.3-0.40.70.1-0.3-0.8-0.40.3-0.3
Time in closed arm after self-admin0.00.00.00.10.10.20.1-0.2-0.00.1-0.10.1
Time in open arm before self-admin0.10.10.50.2-0.1-0.5-0.7-0.60.20.2-0.00.0
Time in open arm after self-admin0.10.10.20.30.3-0.5-0.50.20.4-0.4-0.2-0.2
Sum of active levers in priming session hrs 5-62.32.36.41.51.6-1.21.22.51.61.1-1.50.6
Time to tail flick, vehicle, before self-admin0.20.20.5-0.10.20.30.7-0.1-0.20.70.10.5
Time to tail flick, vehicle, after self-admin0.70.81.80.71.0-0.41.20.00.51.4-0.41.2
Time to tail flick, test, before self-admin1.01.02.7-1.1-1.00.9-0.6-1.6-1.3-0.50.9-0.6
Time to tail flick, test, after self-admin0.00.00.1-0.00.3-0.10.30.20.10.3-0.2-0.2
Delta time to tail flick, vehicle, before/after SA0.20.20.60.40.5-0.30.8-0.10.20.7-0.20.6
Delta time to tail flick, test, before/after SA2.92.64.51.71.8-1.51.12.11.91.2-1.70.8
Ambulatory time before self-admin0.10.10.4-0.20.10.30.60.1-0.20.10.2-0.1
Ambulatory time after self-admin1.01.11.8-1.1-1.21.2-0.4-0.6-1.2-0.81.3-1.0
Total heroin consumption3.33.96.41.62.1-1.12.52.11.72.2-1.72.4
Area under the delay curve0.60.61.2-0.8-1.10.8-0.3-1.1-1.0-0.30.8-0.2
Delay disc. indifference point, 0s delay0.80.92.6-0.9-1.10.7-0.9-1.6-1.0-0.40.8-0.3
Delay disc. indifference point, 16s delay2.12.13.1-1.5-1.71.6-0.9-1.2-1.8-1.31.5-1.5
Delay disc. indifference point, 2s delay0.20.20.6-0.5-0.70.3-0.4-0.2-0.8-0.50.4-0.0
Delay disc. indifference point, 24s delay0.10.10.30.60.2-0.3-0.2-0.20.50.1-0.4-0.1
Delay disc. indifference point, 4s delay0.30.30.8-0.5-0.70.4-0.4-0.9-0.5-0.30.50.1
Delay disc. indifference point, 8s delay0.20.21.0-0.4-0.60.2-0.2-1.0-0.40.10.3-0.0
Delay discount exponential model param0.40.40.90.60.9-0.60.30.90.80.2-0.60.1
Delay discount hyperbolic model param0.30.30.70.50.8-0.50.20.80.70.1-0.5-0.0
Fecal boli incidents, locomotor time 10.20.20.5-0.20.20.70.30.50.0-0.40.4-0.7
Change in fecal boli incidents, locomotor task0.20.10.5-0.1-0.4-0.0-0.1-0.7-0.30.60.20.4
Time >=10cm from walls, locomotor time 13.53.55.2-2.1-2.02.1-0.8-1.8-2.3-1.22.2-1.8
Bouts of movement, locomotor time 10.60.72.30.61.0-0.31.50.80.51.0-0.60.5
Total resting periods, locomotor time 10.30.31.70.30.70.01.30.50.10.7-0.30.2
Rest time, locomotor task time 10.60.71.6-0.4-0.90.2-1.2-0.3-0.7-1.30.4-1.2
Distance moved, locomotor task time 10.20.20.3-0.5-0.40.40.2-0.6-0.40.40.60.5
Vertical activity count, locomotor time 10.50.61.1-0.7-0.70.6-1.1-0.7-0.2-0.90.7-0.9
Time >=10cm from walls, locomotor time 20.10.20.3-0.3-0.50.5-0.0-0.3-0.5-0.20.4-0.6
Bouts of movement, locomotor time 20.20.30.70.30.6-0.10.90.10.30.7-0.50.5
Total resting periods, locomotor time 20.10.10.3-0.00.30.10.6-0.3-0.00.4-0.20.2
Rest time, locomotor task time 21.61.93.1-1.0-1.40.7-1.8-1.4-1.1-1.61.2-1.7
Distance moved, locomotor task time 21.01.12.00.80.8-0.91.21.10.81.4-0.81.4
Vertical activity count, locomotor time 21.11.22.31.31.0-1.40.11.21.50.8-1.30.6
Weight adjusted by age2.22.54.51.31.9-1.21.61.61.32.1-1.41.5
Seeking ratio, delayed vs. immediate footshock0.30.40.8-0.7-0.70.60.1-0.8-0.90.10.6-0.1
Locomotion in novel chamber3.74.67.4-1.8-2.41.4-2.7-1.4-2.0-2.51.8-2.7
Locomotion in novel chamber post-restriction2.02.44.7-1.2-1.61.0-2.1-1.2-1.3-2.21.2-1.7
Progressive ratio0.60.71.7-0.70.00.91.3-0.6-0.80.90.81.1
Food seeking constrained by brief footshock0.50.61.10.80.9-0.70.50.60.81.1-0.80.8
Seeking ratio, punishment vs. effort0.50.61.60.7-0.0-1.0-1.20.20.7-0.4-0.8-0.7
Run reversals in cocaine runway, females0.30.31.1-0.10.30.10.7-0.7-0.11.00.20.9
Run reversals in cocaine runway, males1.41.32.71.41.0-1.5-0.41.41.60.2-1.40.0
Latency to leave start box in cocaine runway0.60.71.1-0.9-0.91.10.0-0.8-1.1-0.61.1-0.4
Latency to leave start box in cocaine runway, F0.20.30.5-0.5-0.50.70.1-0.6-0.7-0.30.7-0.2
Latency to leave start box in cocaine runway, M0.00.00.1-0.2-0.30.20.1-0.0-0.2-0.10.2-0.0
Cd content in liver0.70.82.0-0.6-0.70.4-1.4-0.3-0.4-1.30.5-1.2
Co content in liver0.50.62.00.60.0-1.3-1.4-0.00.8-0.5-0.70.3
Cu content in liver0.10.10.40.00.3-0.40.70.20.20.50.00.5
Fe content in liver0.20.31.00.40.7-0.20.20.50.40.3-0.41.0
K content in liver0.50.52.9-0.10.30.11.7-0.0-0.21.1-0.00.8
Mg content in liver1.41.42.7-1.6-1.11.40.5-1.4-1.7-0.11.5-0.4
Mn content in liver1.31.54.50.61.20.32.11.20.71.4-0.81.6
Na content in liver1.21.32.71.11.0-0.91.11.60.91.0-1.11.5
Rb content in liver2.32.84.0-1.9-1.91.2-1.5-2.0-1.8-1.51.9-1.1
Se content in liver0.81.02.0-1.2-0.71.30.3-0.6-1.1-0.61.1-1.4
Sr content in liver3.22.94.01.71.7-1.51.82.01.81.5-1.71.4
Zn content in liver0.60.62.10.50.6-0.71.40.70.61.1-0.50.3