Ganab

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000019724 0.12 0.07 2.4e-07 0.14 0.12 0.13 0.13 8.9e-08 6.0e-07 1.3e-07 1.5e-07
2 Brain gene expression ENSRNOG00000019724 0.08 0.05 3.9e-10 0.1 0.11 0.1 0.11 1.4e-09 1.0e-10 1.9e-09 1.6e-10
3 Brain isoform ratio ENSRNOT00000035650 0.04 0.03 1.1e-04 0.04 0.05 0.04 0.04 1.4e-04 3.4e-05 1.2e-04 1.2e-04
4 Brain isoform ratio ENSRNOT00000105221 0.04 0.03 8.6e-05 0.04 0.05 0.04 0.04 1.2e-04 2.9e-05 1.2e-04 9.0e-05
5 Brain intron excision ratio chr1:205804237:205805555 0.09 0.05 9.7e-08 0.06 0.08 0.08 0.07 3.3e-06 3.5e-08 1.4e-07 3.2e-07
6 Brain intron excision ratio chr1:205804776:205805555 0.05 0.03 3.5e-05 0.04 0.05 0.04 0.04 1.2e-04 3.5e-05 8.1e-05 2.0e-04
7 LHb gene expression ENSRNOG00000019724 0.2 0.11 8.5e-04 0.03 0.08 0.04 0.03 7.3e-02 5.9e-03 3.6e-02 5.4e-02
8 Liver gene expression ENSRNOG00000019724 0.37 0.17 4.5e-08 0.06 0.04 0.04 0.04 6.1e-07 1.3e-05 1.2e-05 9.4e-06
9 NAcc intron excision ratio chr1:205793961:205797885 0.07 0.04 3.6e-07 0.12 0.1 0.1 0.11 3.9e-09 6.1e-08 5.5e-08 1.6e-08
10 PL gene expression ENSRNOG00000019724 0.06 0.04 8.9e-06 0.07 0.06 0.06 0.07 2.5e-06 1.1e-05 1.2e-05 5.3e-06
11 PL isoform ratio ENSRNOT00000035650 0.04 0.03 2.0e-03 0.02 0.03 0.02 0.01 1.9e-02 5.3e-03 1.7e-02 2.7e-02
12 PL isoform ratio ENSRNOT00000105221 0.04 0.03 3.0e-03 0.02 0.02 0.02 0.01 2.0e-02 7.1e-03 2.2e-02 2.6e-02
13 PL intron excision ratio chr1:205793961:205797885 0.11 0.06 2.1e-12 0.16 0.15 0.15 0.15 4.3e-12 1.1e-11 2.8e-11 2.1e-11
14 PL intron excision ratio chr1:205804237:205805555 0.06 0.04 2.8e-04 0.05 0.04 0.04 0.04 1.2e-04 4.9e-04 8.9e-04 9.2e-04
15 PL intron excision ratio chr1:205804776:205805555 0.06 0.04 2.2e-04 0.02 0.03 0.03 0.02 1.7e-02 1.2e-03 1.4e-03 6.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail2.37.413.12.52.7-1.61.62.1-2.33.5-2.52.52.5-3.63.52.62.5-3.5
BMI without tail0.91.93.01.21.6-1.01.00.8-1.01.7-1.41.41.4-1.71.71.31.4-1.6
Body weight3.314.217.83.84.1-3.43.42.9-3.34.2-3.83.73.8-4.14.13.93.8-4.0
Epididymis fat weight0.40.81.9-0.9-0.91.4-1.4-0.70.8-0.41.0-1.1-1.00.3-0.4-0.9-1.00.3
Glucose2.74.25.9-2.1-2.22.4-2.4-1.51.8-1.72.3-2.3-2.31.5-1.6-2.1-2.31.5
Heart weight1.01.52.2-1.1-1.01.5-1.5-1.51.5-0.81.3-1.3-1.30.8-0.9-1.2-1.30.9
Left kidney weight0.10.10.50.20.10.0-0.00.7-0.50.5-0.10.10.1-0.60.60.10.1-0.6
Right kidney weight0.20.61.70.60.4-0.30.31.3-1.10.8-0.40.40.4-1.01.00.50.4-1.1
Tail length0.72.13.91.51.8-2.02.00.9-1.21.2-1.61.61.6-0.91.01.51.6-0.9
Length with tail2.17.79.42.93.1-3.03.02.2-2.62.8-2.82.82.8-2.52.62.92.8-2.5
Length without tail1.94.14.72.22.1-2.02.01.8-2.02.1-2.02.02.0-2.02.12.22.0-2.0
Liver weight, left0.40.70.9-0.8-0.70.7-0.7-0.90.9-0.80.9-0.9-0.90.9-0.9-0.5-0.90.9
Liver weight, right0.00.10.2-0.00.00.3-0.3-0.50.40.20.2-0.2-0.2-0.10.10.2-0.2-0.1
Parametrial fat weight1.22.34.3-1.6-1.82.1-2.1-0.91.2-1.11.7-1.7-1.70.9-1.0-1.7-1.70.8
Retroperitoneal fat weight2.48.011.8-3.0-2.93.4-3.4-2.52.8-2.33.1-3.1-3.12.0-2.2-2.9-3.12.1
Intraocular pressure0.10.10.3-0.3-0.40.0-0.00.00.1-0.60.4-0.5-0.40.6-0.5-0.3-0.40.5
Extensor digitorum longus weight6.325.128.35.25.3-4.94.94.1-4.65.3-5.05.15.0-5.15.25.25.0-5.1
Soleus weight2.88.19.0-3.0-2.93.0-3.0-2.72.9-2.82.8-2.8-2.82.7-2.8-3.0-2.82.7
Tibialis anterior weight10.235.137.26.06.0-6.06.05.4-5.85.9-6.16.16.1-5.75.86.06.1-5.7
Tibia length2.05.710.42.01.8-2.12.13.2-3.02.2-2.32.32.3-2.52.52.02.3-2.6
Number of licking bursts0.00.00.1-0.0-0.00.1-0.1-0.00.0-0.00.10.3-0.10.0-0.0-0.1-0.10.0
Food consumed during 24 hour testing period0.10.10.7-0.2-0.40.2-0.20.00.0-0.40.4-0.8-0.40.4-0.4-0.0-0.40.3
Times rat made contact with spout0.10.10.20.30.4-0.50.5-0.30.10.1-0.40.30.40.1-0.10.40.40.2
Mean time between licks in bursts0.30.51.30.91.2-0.70.7-0.60.20.8-0.7-0.00.7-0.50.51.00.7-0.3
Mean num. licks in bursts0.10.10.2-0.1-0.0-0.00.0-0.40.4-0.30.1-0.5-0.10.4-0.4-0.0-0.10.4
Std. dev. time between licks in bursts0.40.41.9-0.3-0.20.5-0.5-1.41.1-0.50.5-0.3-0.50.7-0.7-0.3-0.50.8
Water consumed over 24 hours0.30.40.80.70.7-0.80.80.2-0.40.4-0.60.90.6-0.30.30.80.6-0.3
Indifference point 0 sec0.61.02.80.81.0-0.90.90.7-0.81.0-1.01.71.0-0.90.90.91.0-0.9
Indifference point AUC2.73.25.81.81.5-1.91.92.4-2.31.6-1.61.31.6-1.61.71.81.6-1.8
Indifference point function ln k4.46.313.1-2.3-2.02.8-2.8-3.63.4-2.02.3-1.8-2.32.1-2.2-2.3-2.32.3
Indifference point function log k4.46.313.1-2.3-2.02.8-2.8-3.63.4-2.02.3-1.8-2.32.1-2.2-2.3-2.32.3
Delay discounting total patch changes 0 sec0.50.82.00.81.0-0.90.90.4-0.60.8-0.91.40.9-0.70.80.90.9-0.7
Delay discounting total patch changes 12 sec7.19.510.93.13.0-3.33.33.2-3.32.9-3.13.33.1-2.82.93.13.1-2.9
Delay discounting total patch changes 18 sec0.60.81.40.90.8-1.11.11.2-1.10.7-0.90.40.9-0.70.71.00.9-0.7
Delay discounting total patch changes 24 sec7.29.010.53.23.2-3.03.02.7-2.93.2-3.02.13.0-3.13.13.23.0-3.1
Delay discounting total patch changes 6 sec1.21.82.71.41.4-1.31.31.0-1.21.4-1.31.61.3-1.41.41.51.3-1.3
Delay discounting time to switch 0 sec0.61.01.70.90.6-0.50.51.3-1.11.1-0.91.00.9-1.31.20.70.9-1.3
Delay discounting water rate 0 sec0.60.91.6-0.9-0.70.7-0.7-1.31.2-1.00.9-0.2-0.91.2-1.2-0.7-0.91.2
Delay discounting water rate 12 sec2.53.87.6-1.8-1.41.7-1.7-2.82.6-1.81.8-1.9-1.82.0-2.0-1.6-1.82.1
Delay discounting water rate 18 sec1.21.65.2-1.0-0.61.3-1.2-2.32.0-0.91.1-1.1-1.11.1-1.1-0.9-1.11.2
Delay discounting water rate 24 sec1.62.24.0-1.3-1.21.4-1.4-2.01.9-1.51.4-1.0-1.41.6-1.6-1.3-1.41.6
Delay discounting water rate 6 sec1.82.65.5-1.4-1.11.4-1.4-2.32.2-1.41.4-1.7-1.41.6-1.7-1.4-1.41.8
Locomotor activity1.11.84.2-1.2-0.81.0-1.0-2.01.9-1.31.2-0.5-1.21.5-1.5-1.1-1.21.6
Locomotor testing distance1.32.26.0-1.3-0.81.3-1.2-2.52.2-1.31.3-0.6-1.31.5-1.5-1.3-1.31.7
Locomotor testing rearing1.32.14.3-1.4-1.11.3-1.3-2.11.9-1.31.3-1.1-1.31.5-1.5-1.3-1.31.6
Light reinforcement 10.10.20.5-0.4-0.40.2-0.2-0.50.5-0.60.30.0-0.30.7-0.6-0.3-0.30.7
Light reinforcement 20.20.20.8-0.3-0.70.4-0.40.9-0.5-0.20.4-0.7-0.4-0.10.1-0.5-0.4-0.2
Reaction time number correct0.30.40.90.80.9-0.90.90.0-0.30.6-0.6-0.40.6-0.40.40.90.6-0.4
Reaction time mean minus median0.60.83.30.90.4-1.01.01.8-1.60.4-0.60.30.6-0.60.60.80.6-0.7
Reaction time mean minus median AUC0.20.31.10.50.2-0.80.81.0-0.9-0.0-0.2-0.20.20.00.00.50.2-0.1
Reaction time num false alarms0.40.62.3-0.7-0.30.4-0.4-1.51.3-0.70.40.2-0.40.9-0.9-0.5-0.41.1
Reaction time num false alarms AUC0.20.21.2-0.20.3-0.20.2-1.10.8-0.3-0.10.80.10.5-0.50.10.10.7
Reaction time trials correct on left0.30.40.90.80.9-0.90.90.0-0.30.6-0.6-0.40.6-0.40.40.90.6-0.4
Reaction time trials on left0.30.40.90.81.0-0.90.90.1-0.30.6-0.6-0.40.6-0.40.41.00.6-0.4
Reaction time mean0.10.10.60.1-0.3-0.20.20.7-0.6-0.30.0-0.1-0.00.2-0.10.0-0.00.0
Reaction time mean AUC0.10.10.3-0.0-0.5-0.00.00.6-0.4-0.40.2-0.2-0.20.3-0.3-0.1-0.20.2
Median of all reaction times0.10.10.40.3-0.1-0.20.20.6-0.50.0-0.20.10.2-0.10.10.20.2-0.2
Reaction time omissions0.10.10.40.50.2-0.70.70.3-0.3-0.1-0.20.00.20.2-0.10.40.20.2
Reaction time false alarm rate0.30.41.1-0.7-0.30.5-0.4-1.11.0-0.60.30.8-0.30.7-0.7-0.5-0.30.8
Reaction time premature initiation rate3.24.26.42.32.5-2.02.00.9-1.42.4-2.31.32.3-2.12.12.32.3-2.0
Reaction time premature initiations3.85.48.62.72.9-2.62.61.0-1.62.5-2.51.22.5-2.12.22.72.5-2.0
Std. dev. reaction times0.10.10.60.0-0.4-0.30.30.8-0.6-0.60.2-0.0-0.20.5-0.4-0.0-0.20.3
Reaction time trials completed0.30.40.90.81.0-0.90.90.1-0.30.6-0.6-0.40.6-0.40.41.00.6-0.4
Reaction time trials AUC0.20.30.70.70.8-0.70.7-0.1-0.20.5-0.5-0.50.5-0.30.40.80.5-0.3
Social response proportion0.20.22.30.20.4-0.30.30.0-0.10.3-0.31.50.3-0.30.30.30.3-0.3
Social responses0.10.11.30.10.3-0.50.5-0.20.1-0.1-0.11.10.10.3-0.20.20.10.3
Social time0.10.10.3-0.30.0-0.20.2-0.40.3-0.30.2-0.3-0.20.5-0.4-0.1-0.20.5
Conditioned locomotion0.60.70.90.80.9-0.80.80.6-0.70.8-0.80.90.8-0.80.80.90.8-0.8
Cocaine response after cond. corrected0.91.02.2-1.0-0.71.1-1.1-1.51.4-0.70.8-1.3-0.80.8-0.8-0.9-0.80.9
Cocaine response after cond. not corrected0.70.71.6-0.8-0.71.0-1.0-1.31.2-0.60.6-1.1-0.60.7-0.7-0.7-0.60.7
Cocaine response before conditioning0.40.52.00.70.4-0.70.70.9-0.90.4-0.71.40.7-0.40.50.60.7-0.6
Saline control response1.92.63.61.81.9-1.81.81.0-1.31.6-1.90.41.9-1.41.51.81.9-1.4
Condit. Reinf. active minus inactive responses0.20.20.6-0.6-0.80.4-0.40.20.0-0.60.5-0.4-0.50.5-0.5-0.6-0.50.4
Condit. Reinf. active-inactive response ratio0.40.41.1-0.8-1.00.8-0.80.6-0.2-0.50.6-0.7-0.60.2-0.2-0.8-0.60.1
Condit. Reinf. active responses0.00.00.2-0.0-0.1-0.10.10.1-0.1-0.1-0.10.40.10.1-0.10.00.10.0
Condit. Reinf. inactive responses0.10.20.60.30.4-0.30.3-0.80.40.0-0.30.70.30.2-0.20.40.30.3
Condit. Reinf. lever presses1.01.43.31.10.9-1.01.01.2-1.31.1-1.11.81.1-1.11.11.21.1-1.2
Condit. Reinf. lever reinforcers received0.10.20.50.30.2-0.50.50.5-0.50.2-0.40.70.4-0.20.20.40.4-0.2
Pavlov. Cond. lever latency0.60.83.4-0.8-0.70.6-0.6-0.80.8-0.90.8-1.8-0.80.9-0.9-0.9-0.80.9
Pavlov. Cond. magazine entry latency5.05.89.02.42.3-2.52.52.1-2.32.2-2.63.02.6-2.12.12.42.6-2.2
Pavlov. Cond. change in total contacts1.72.43.51.61.2-1.41.41.9-1.91.3-1.51.61.5-1.41.41.71.5-1.6
Pavlov. Cond. index score3.24.17.62.01.7-1.91.92.1-2.11.9-2.02.82.0-1.91.92.12.0-2.0
Pavlov. Cond. latency score3.03.88.01.91.6-1.71.72.0-2.01.8-1.92.81.9-1.81.91.91.9-1.9
Pavlov. Cond. lever contacts0.60.84.50.80.6-0.70.70.7-0.80.6-0.82.10.8-0.60.60.90.8-0.6
Pavlov. Cond. magazine entry number7.99.810.9-3.2-3.03.2-3.2-3.03.2-2.93.3-3.2-3.32.9-2.9-3.3-3.33.0
Pavlov. Cond. intertrial magazine entries1.82.34.0-1.7-1.61.4-1.4-1.01.2-1.51.5-2.0-1.51.5-1.5-1.6-1.51.4
Pavlov. Cond. lever-magazine prob. diff.3.54.57.02.11.8-2.02.02.1-2.21.9-2.22.72.2-1.92.02.22.2-2.1
Pavlov. Cond. response bias1.82.55.31.61.4-1.61.61.5-1.61.4-1.62.31.6-1.41.41.71.6-1.4
Conditioned reinforcement - actives1.61.62.7-1.4-1.61.3-1.3-0.40.7-1.41.3-1.6-1.31.2-1.2-1.4-1.31.1
Conditioned reinforcement - inactives0.50.61.3-1.0-1.11.1-1.1-0.00.3-0.60.8-0.6-0.80.4-0.4-1.0-0.80.3
Conditioned locomotion1.51.93.5-1.5-1.61.9-1.9-0.91.2-1.11.5-1.2-1.50.8-0.9-1.5-1.50.8
Intermittent access intake day 1-15 change1.01.01.8-1.0-1.30.7-0.7-0.00.3-1.31.1-1.0-1.11.2-1.2-1.0-1.11.1
Intermittent access intake escalation0.60.61.1-0.7-1.00.5-0.50.10.2-1.00.8-0.6-0.81.0-0.9-0.7-0.80.8
Intermittent access intake escalation 20.10.10.70.1-0.2-0.30.30.8-0.6-0.2-0.10.30.10.1-0.10.00.1-0.0
Intermitt. access day 1 inactive lever presses1.61.72.8-1.5-1.51.6-1.6-0.91.1-1.21.3-1.1-1.31.0-1.1-1.7-1.31.0
Intermitt. access day 15 inactive lever presses0.20.30.80.20.00.1-0.10.8-0.70.6-0.10.50.1-0.80.80.10.1-0.9
Intermitt. access escalation Index0.40.31.1-0.4-0.30.7-0.7-1.00.9-0.30.6-0.3-0.60.3-0.4-0.5-0.60.4
Intermittent access day 1 total infusions0.70.82.9-1.0-0.91.7-1.7-0.50.7-0.00.7-0.7-0.7-0.30.1-0.9-0.7-0.2
Intermittent access day 15 total infusions2.42.64.8-1.9-2.12.2-2.2-0.81.2-1.41.7-1.6-1.71.1-1.2-1.8-1.71.0
Intermittent access terminal intake (last 3 days)0.30.31.2-0.7-0.91.1-1.10.4-0.1-0.10.4-0.3-0.4-0.30.2-0.6-0.4-0.3
Intermittent access total infusions0.50.62.0-0.9-1.11.4-1.4-0.10.4-0.30.7-0.6-0.7-0.0-0.1-0.9-0.7-0.1
Intermittent access day 1 locomotion0.30.31.3-0.3-0.21.1-1.1-0.40.50.60.1-0.1-0.1-0.80.7-0.3-0.1-0.7
Intermittent access day 15 total locomotion0.10.20.5-0.3-0.40.7-0.70.3-0.10.20.2-0.1-0.2-0.50.4-0.3-0.2-0.5
Intermittent access total locomotion0.40.51.4-0.2-0.31.0-1.00.6-0.30.7-0.0-0.10.0-1.21.0-0.20.0-1.2
Intermittent access standard deviation1.01.11.7-1.2-1.30.9-0.9-0.40.6-1.31.0-1.0-1.01.2-1.2-1.1-1.01.1
Cocaine induced anxiety0.40.51.60.50.5-0.60.60.9-0.90.6-0.61.30.6-0.60.60.70.6-0.7
Post-drug Anxiety0.91.02.20.90.7-1.01.01.4-1.30.8-0.91.50.9-0.90.90.90.9-1.0
Baseline Anxiety0.90.91.41.11.2-1.21.20.7-0.90.9-1.00.41.0-0.80.91.01.0-0.8
Lifetime Intake0.60.72.1-1.0-1.01.5-1.5-0.50.7-0.40.7-0.5-0.70.1-0.2-0.9-0.70.1
Incentive Sensitization - Responses0.30.30.70.30.2-0.10.10.8-0.70.6-0.30.10.3-0.80.70.30.3-0.8
Incentive Sensitization - Breakpoint0.20.20.60.20.10.0-0.00.8-0.60.5-0.20.00.2-0.70.60.20.2-0.7
Progressive ratio test 1 active lever presses1.51.62.3-1.5-1.51.5-1.5-0.91.1-1.31.1-1.3-1.11.0-1.1-1.5-1.11.0
Progressive ratio test 1 breakpoint1.81.82.6-1.6-1.61.6-1.6-0.91.2-1.41.2-1.4-1.21.2-1.2-1.6-1.21.2
Progressive ratio test 1 inactive lever presses0.10.10.20.10.30.1-0.1-0.10.00.4-0.40.30.4-0.50.40.00.4-0.4
Progressive ratio test 2 active lever presses1.11.22.3-1.3-1.41.5-1.5-0.40.7-0.91.0-1.3-1.00.6-0.7-1.3-1.00.6
Progressive ratio test 2 breakpoint2.02.23.5-1.7-1.91.8-1.8-0.71.0-1.41.5-1.8-1.51.1-1.2-1.7-1.51.1
Progressive ratio test 2 inactive lever presses0.30.41.3-0.8-0.91.1-1.10.10.2-0.30.5-0.4-0.5-0.1-0.0-0.9-0.5-0.1
Total sessions with >9 infusions1.51.73.4-1.4-1.31.8-1.9-1.31.4-0.91.3-1.2-1.30.7-0.8-1.3-1.30.8
Short access day 1 total inactive lever presses0.80.92.0-1.0-0.91.4-1.4-1.01.1-0.50.8-1.0-0.80.4-0.5-1.0-0.80.4
Short access day 10 total inactive lever presses2.83.04.2-1.7-1.61.8-1.8-2.02.1-1.61.8-1.3-1.81.6-1.7-1.8-1.81.7
Short access day 1 total infusions0.80.92.0-1.1-0.91.4-1.4-1.11.1-0.60.8-0.7-0.80.5-0.6-1.0-0.80.5
Short access day 10 total infusions0.30.31.4-0.5-0.51.2-1.2-0.40.50.30.3-0.4-0.3-0.50.4-0.4-0.3-0.4
Short access total infusions0.40.41.5-0.7-0.61.2-1.2-0.80.8-0.10.5-0.3-0.5-0.1-0.0-0.7-0.50.0
Short access day 1 locomotion0.20.20.80.20.20.5-0.5-0.10.10.7-0.20.10.2-0.90.80.20.2-0.8
Short access day 10 total locomotion0.10.20.60.10.10.4-0.40.1-0.00.6-0.10.10.1-0.80.70.00.1-0.7
Short access total locomotion0.40.41.40.40.50.3-0.30.1-0.21.0-0.50.30.5-1.21.10.30.5-1.1
Compulsive drug intake0.60.61.60.91.3-1.21.2-0.4-0.00.5-0.70.90.7-0.10.20.90.7-0.0
One hour access (0.3 mA shock)3.13.65.9-2.2-2.32.4-2.4-1.21.6-1.71.9-1.7-1.91.4-1.5-2.2-1.91.4
One hour access (shock baseline)3.54.07.3-2.3-2.72.5-2.5-0.71.3-2.02.0-1.8-2.01.5-1.6-2.4-2.01.4
Number of responses in last shaping day0.00.00.3-0.10.10.1-0.1-0.60.4-0.0-0.0-0.10.00.1-0.10.10.00.2
Context. condit. distance diff. score0.40.40.9-0.7-0.50.9-0.9-1.00.9-0.30.6-0.5-0.60.3-0.4-0.8-0.60.4
Locomotion velocity, session 10.10.10.6-0.10.20.2-0.2-0.80.60.1-0.10.10.1-0.00.0-0.10.10.1
Locomotion distance, session 10.40.61.00.60.9-0.40.40.0-0.21.0-0.90.90.9-1.00.90.60.9-0.9
Locomotion velocity, session 22.83.33.91.61.8-1.71.71.5-1.61.9-2.02.02.0-1.91.91.72.0-1.9
Locomotion distance, session 20.10.20.40.30.6-0.40.40.0-0.10.5-0.60.60.6-0.50.50.30.6-0.4
Locomotion velocity, session 30.30.31.00.40.60.1-0.10.0-0.11.0-0.50.50.5-1.00.90.30.5-0.9
Locomotion distance, session 30.00.00.10.20.2-0.00.0-0.40.20.2-0.10.10.1-0.10.10.20.1-0.0
Stereotopy head waving bouts, day 30.20.20.7-0.6-0.20.8-0.8-0.10.30.40.1-0.2-0.1-0.60.4-0.5-0.1-0.5
Stereotopy head waving duration, day 30.10.20.5-0.6-0.20.7-0.7-0.40.40.10.2-0.2-0.2-0.20.1-0.6-0.2-0.1
Locomotion velocity, session 70.00.00.1-0.3-0.20.4-0.40.10.00.10.1-0.0-0.1-0.30.2-0.3-0.1-0.2
Locomotion distance, session 70.10.20.6-0.4-0.20.6-0.6-0.80.7-0.00.4-0.3-0.40.0-0.1-0.5-0.40.2
Stereotopy head waving bouts, day 70.30.31.00.30.2-0.30.31.0-0.80.6-0.50.50.5-0.70.70.30.5-0.8
Stereotopy head waving duration, day 72.12.63.01.51.5-1.51.51.7-1.71.7-1.61.61.6-1.71.71.61.6-1.7
Locomotion velocity, session 80.10.10.7-0.30.00.2-0.2-0.80.7-0.20.0-0.0-0.00.3-0.3-0.3-0.00.4
Locomotion distance, session 80.20.30.8-0.7-0.40.9-0.9-0.60.6-0.10.4-0.4-0.4-0.0-0.1-0.7-0.40.1
Degree of sensitization distance0.10.10.4-0.3-0.20.7-0.7-0.10.20.30.3-0.2-0.3-0.50.4-0.3-0.3-0.4
Degree of sensitization stereotypy1.31.42.41.00.9-1.11.11.6-1.51.1-1.21.21.2-1.21.21.01.2-1.3
Condit. Reinf. active minus inactive responses1.11.21.41.11.1-1.11.10.9-1.11.1-1.21.21.2-1.11.11.11.2-1.1
Condit. Reinf. active-inactive response ratio0.40.40.70.70.7-0.80.80.4-0.50.5-0.70.70.7-0.40.40.70.7-0.4
Condit. Reinf. active responses1.21.42.01.01.0-1.00.91.4-1.41.3-1.21.21.2-1.41.31.01.2-1.4
Condit. Reinf. inactive responses0.10.10.5-0.0-0.20.2-0.20.7-0.50.3-0.0-0.00.0-0.50.5-0.00.0-0.6
Incentive salience index mean1.41.62.11.21.3-1.11.11.0-1.21.4-1.31.31.3-1.41.41.21.3-1.4
Condit. Reinf. lever presses0.71.01.61.00.9-0.70.60.8-0.91.2-1.01.01.0-1.31.20.91.0-1.3
Time in familiar zone, hab. session 10.10.10.20.30.3-0.10.10.0-0.10.4-0.20.20.2-0.30.30.40.2-0.3
Time in novel zone, hab. session 11.71.72.1-1.2-1.21.1-1.1-1.41.4-1.31.3-1.3-1.31.4-1.4-1.3-1.31.4
Total zone transitions, hab. session 10.20.30.40.40.6-0.60.60.5-0.50.6-0.70.60.7-0.50.60.50.7-0.5
Total locomotion distance, hab. session 10.00.10.2-0.4-0.30.4-0.50.2-0.10.10.1-0.1-0.1-0.30.2-0.3-0.1-0.3
Locomotion velocity, hab. session 10.20.30.50.20.3-0.20.20.7-0.60.6-0.50.50.5-0.70.70.20.5-0.7
Time in familiar zone, hab. session 20.70.71.5-0.3-0.50.4-0.4-1.21.0-0.90.8-0.7-0.81.2-1.1-0.4-0.81.2
Time in novel zone, hab. session 20.70.71.30.60.7-0.50.50.9-0.81.0-0.80.80.8-1.21.10.60.8-1.1
Total zone transitions, hab. session 21.21.62.21.31.5-1.11.10.6-0.81.5-1.41.41.4-1.41.41.31.4-1.3
Total locomotion distance, hab. session 20.10.20.40.20.4-0.00.00.0-0.10.6-0.40.40.4-0.60.60.20.4-0.6
Locomotion velocity, hab. session 20.10.10.30.00.20.2-0.20.1-0.10.5-0.30.30.3-0.60.50.10.3-0.5
Novel to familiar place preference ratio2.42.63.61.41.5-1.51.51.9-1.91.7-1.51.51.5-1.71.71.51.5-1.8
Novelty place preference1.51.52.61.01.1-1.11.11.6-1.51.3-1.11.11.1-1.41.41.21.1-1.4
Time in novel zone, NPP test1.51.62.41.11.2-1.21.21.5-1.51.3-1.11.21.1-1.41.41.21.1-1.4
Total zone transitions, NPP test1.11.62.21.21.4-1.21.20.7-0.91.3-1.51.51.5-1.21.31.21.5-1.2
Total locomotion distance, NPP test0.10.10.20.00.3-0.00.0-0.10.00.4-0.50.40.5-0.40.40.00.5-0.3
Locomotion velocity, NPP test0.00.10.1-0.10.2-0.00.0-0.10.10.2-0.40.40.4-0.30.2-0.10.4-0.2
Pavlov. Cond. lever latency1.31.72.6-1.2-1.20.9-0.9-1.21.3-1.51.3-1.3-1.31.6-1.5-1.2-1.31.6
Pavlov. Cond. magazine entry latency1.31.72.51.31.0-1.01.01.6-1.51.4-1.21.21.2-1.51.51.21.2-1.6
Pavlov. Cond. change in total contacts0.60.61.80.60.3-0.50.51.4-1.20.7-0.70.70.7-0.90.90.60.7-1.0
Pavlov. Cond. index score0.71.01.41.00.7-0.80.81.2-1.20.9-1.00.91.0-1.01.01.01.0-1.1
Pavlov. Cond. latency score0.60.71.00.90.7-0.70.70.9-0.90.9-0.90.80.9-0.90.90.90.9-1.0
Pavlov. Cond. lever contacts0.30.30.60.60.5-0.30.30.6-0.60.7-0.50.50.5-0.70.70.60.5-0.8
Pavlov. Cond. magazine entry number0.91.22.2-1.1-0.71.1-1.1-1.51.4-0.81.1-1.1-1.10.9-1.0-1.0-1.11.0
Pavlov. Cond. intertrial magazine entries0.10.10.50.10.0-0.50.40.7-0.6-0.0-0.30.30.3-0.00.10.00.3-0.1
Pavlov. Cond. lever-magazine prob. diff.1.01.22.01.10.8-1.01.01.4-1.41.1-1.11.11.1-1.11.21.11.1-1.2
Pavlov. Cond. response bias0.91.11.91.00.8-0.90.91.4-1.31.0-1.01.01.0-1.11.11.01.0-1.2
Bone: apparent density0.30.51.00.80.6-0.30.30.7-0.70.9-0.50.60.5-1.00.90.70.5-1.0
Bone surface2.13.75.31.91.6-1.51.52.2-2.22.1-1.71.81.7-2.22.21.91.7-2.3
Bone volume1.01.62.71.30.9-0.80.81.6-1.51.4-1.01.11.0-1.61.51.21.0-1.7
Bone: connectivity density1.72.73.71.71.6-1.31.31.4-1.51.9-1.51.61.5-1.91.91.61.5-1.9
Bone: cortical apparent density0.50.61.10.80.8-1.01.00.6-0.70.5-0.90.90.9-0.40.50.80.9-0.4
Bone: cortical area0.91.41.81.11.0-1.01.01.3-1.31.2-1.21.21.2-1.31.31.21.2-1.3
Bone: cortical porosity0.00.00.1-0.2-0.2-0.10.10.1-0.0-0.30.1-0.1-0.10.3-0.3-0.2-0.10.3
Bone: cortical porosity0.10.10.20.20.2-0.40.40.2-0.2-0.1-0.20.20.20.1-0.10.20.20.1
Bone: cortical thickness2.64.46.32.22.3-2.52.51.4-1.71.8-2.42.32.4-1.51.62.22.4-1.5
Bone: cortical thickness0.40.40.70.90.8-0.90.9-0.1-0.20.4-0.80.80.8-0.20.30.70.8-0.2
Bone: cortical tissue density0.60.71.40.90.9-1.21.20.7-0.80.6-1.01.01.0-0.50.50.81.0-0.5
Bone: elastic displacement0.80.91.5-0.8-0.60.5-0.5-1.21.1-1.00.8-0.8-0.81.2-1.1-0.8-0.81.2
Bone: elastic work0.50.71.30.91.1-1.01.00.0-0.30.8-1.00.91.0-0.50.61.01.0-0.5
Bone: endosteal estimation0.92.04.8-1.5-1.72.2-2.2-0.61.0-0.71.6-1.6-1.60.3-0.5-1.4-1.60.3
Bone: endosteal perimeter1.32.76.1-1.8-2.22.4-2.5-0.30.8-1.01.9-1.9-1.90.5-0.7-1.7-1.90.5
Bone: final force2.23.54.51.91.8-1.61.61.7-1.82.1-1.91.91.9-2.12.11.91.9-2.1
Bone: final moment2.03.44.21.81.7-1.51.51.7-1.82.0-1.81.81.8-2.02.01.91.8-2.1
Bone: marrow area1.12.35.3-1.6-1.82.3-2.3-0.71.1-0.81.8-1.7-1.80.4-0.6-1.6-1.80.4
Bone: maximum diameter0.30.51.40.40.2-0.20.21.2-1.00.7-0.60.50.6-1.00.90.50.6-1.0
Bone: maximum force3.05.18.02.22.0-1.61.62.3-2.32.6-2.12.12.1-2.82.72.22.1-2.8
Bone: maximum moment2.74.77.22.11.9-1.61.52.2-2.22.5-2.02.02.0-2.72.62.12.0-2.7
Bone: minimum diameter0.40.82.4-0.9-1.11.6-1.6-0.10.4-0.21.0-1.1-1.0-0.1-0.1-0.9-1.0-0.1
Bone: periosteal estimation0.10.20.7-0.1-0.40.6-0.60.7-0.40.50.1-0.1-0.1-0.80.7-0.0-0.1-0.8
Bone: periosteal perimeter0.10.10.6-0.1-0.30.3-0.40.8-0.50.30.0-0.0-0.0-0.50.50.0-0.0-0.6
Bone: post-yield work0.30.41.0-0.2-0.71.0-1.00.8-0.50.40.5-0.4-0.5-0.80.7-0.2-0.5-0.9
Bone: stiffness1.01.52.61.20.9-0.90.91.6-1.51.3-1.11.11.1-1.51.41.21.1-1.5
Bone: tissue strength0.40.40.5-0.6-0.50.5-0.5-0.60.6-0.60.7-0.7-0.70.6-0.6-0.5-0.70.6
Bone: trabecular number0.81.22.11.21.0-0.70.71.1-1.11.4-0.91.00.9-1.41.41.10.9-1.5
Bone: trabecular spacing0.50.71.5-0.6-0.50.4-0.4-1.21.1-1.00.6-0.6-0.61.2-1.1-0.6-0.61.2
Bone: trabecular thickness0.20.20.4-0.3-0.70.5-0.50.2-0.0-0.40.6-0.6-0.60.2-0.3-0.4-0.60.2
Bone: trabecular tissue density4.36.17.1-2.6-2.52.3-2.3-2.22.4-2.72.4-2.4-2.42.6-2.6-2.6-2.42.6
Breakpoint value in progressive ratio session2.22.53.61.51.5-1.91.91.8-1.81.2-1.61.61.6-1.21.31.61.6-1.3
Distance traveled before self-admin2.62.83.61.81.5-1.71.71.9-1.91.6-1.61.71.6-1.61.61.71.6-1.7
Distance traveled after self-admin0.30.30.60.70.5-0.70.70.8-0.80.4-0.30.40.3-0.40.40.70.3-0.4
Delta time in closed arm before/after self-admin1.01.02.21.01.5-0.80.9-0.2-0.11.3-1.01.01.0-1.11.01.01.0-0.9
Delta time in open arm before/after self-admin2.32.23.81.41.1-1.41.41.9-1.91.2-1.51.51.5-1.31.41.31.5-1.5
Diff in mean of infusions in LGA sessions1.82.03.31.51.5-1.81.81.3-1.41.1-1.51.51.5-0.91.01.41.5-0.9
Extinction: sum of active levers before priming4.14.15.12.32.0-2.12.12.0-2.12.0-2.02.02.0-1.92.02.22.0-2.0
Active lever presses in extinction session 63.33.24.41.81.5-2.02.02.1-2.11.5-1.81.91.8-1.41.51.61.8-1.6
Delta distance traveled before/after self-admin0.90.91.4-0.8-0.70.8-0.8-1.21.1-0.91.1-1.0-1.11.0-1.0-0.7-1.11.1
Delta ambulatory time before/after self-admin1.41.52.2-1.1-1.01.0-1.0-1.51.4-1.21.3-1.2-1.31.3-1.3-1.0-1.31.4
Time in closed arm before self-admin0.00.00.4-0.1-0.20.0-0.10.6-0.4-0.00.1-0.1-0.1-0.10.1-0.0-0.1-0.2
Time in closed arm after self-admin0.70.71.1-0.9-0.60.9-0.9-1.11.0-0.60.9-0.9-0.90.7-0.7-0.8-0.90.7
Time in open arm before self-admin1.61.74.7-1.1-0.71.1-1.0-2.21.9-1.11.1-1.1-1.11.3-1.3-1.1-1.11.5
Time in open arm after self-admin0.10.10.20.20.2-0.40.4-0.1-0.0-0.1-0.30.30.30.2-0.20.20.30.2
Sum of active levers in priming session hrs 5-61.71.74.51.20.8-1.61.62.1-2.00.7-1.21.21.2-0.80.91.11.2-1.0
Time to tail flick, vehicle, before self-admin0.80.81.70.70.7-0.30.31.0-0.91.1-0.80.80.8-1.31.20.70.8-1.3
Time to tail flick, vehicle, after self-admin0.30.30.60.60.8-0.30.3-0.0-0.20.8-0.60.50.6-0.70.70.60.6-0.7
Time to tail flick, test, before self-admin0.30.30.90.40.60.1-0.1-0.20.00.9-0.30.20.3-0.90.80.60.3-0.8
Time to tail flick, test, after self-admin0.10.10.2-0.3-0.30.2-0.2-0.20.3-0.40.3-0.4-0.30.4-0.4-0.3-0.30.4
Delta time to tail flick, vehicle, before/after SA0.00.00.20.00.1-0.00.0-0.50.4-0.10.00.0-0.00.2-0.2-0.0-0.00.2
Delta time to tail flick, test, before/after SA0.20.10.4-0.1-0.3-0.40.40.4-0.3-0.60.00.0-0.00.7-0.6-0.2-0.00.5
Ambulatory time before self-admin2.52.74.21.61.3-1.71.72.1-2.01.4-1.61.71.6-1.51.51.41.6-1.6
Ambulatory time after self-admin0.30.30.80.60.3-0.50.50.9-0.90.5-0.30.40.3-0.60.60.70.3-0.7
Total heroin consumption3.74.46.72.22.2-2.62.61.9-2.11.7-2.22.32.2-1.51.62.22.2-1.6
Area under the delay curve0.00.00.10.00.20.2-0.2-0.20.20.30.0-0.1-0.0-0.30.30.0-0.0-0.3
Delay disc. indifference point, 0s delay0.40.40.9-0.6-0.30.9-0.9-1.00.9-0.10.5-0.7-0.50.0-0.1-0.7-0.50.2
Delay disc. indifference point, 16s delay0.10.10.40.30.2-0.10.10.4-0.40.5-0.20.00.2-0.60.60.30.2-0.6
Delay disc. indifference point, 2s delay0.20.20.6-0.5-0.40.7-0.8-0.30.4-0.10.5-0.5-0.5-0.0-0.1-0.4-0.50.0
Delay disc. indifference point, 24s delay0.10.10.20.20.4-0.10.2-0.30.20.3-0.20.10.2-0.20.20.40.2-0.1
Delay disc. indifference point, 4s delay0.20.20.50.40.7-0.20.2-0.30.10.7-0.50.30.5-0.60.60.40.5-0.5
Delay disc. indifference point, 8s delay0.50.51.0-0.7-0.40.7-0.7-1.01.0-0.50.7-0.6-0.70.5-0.6-0.6-0.70.7
Delay discount exponential model param0.00.00.1-0.0-0.2-0.20.20.2-0.2-0.3-0.00.10.00.3-0.3-0.10.00.2
Delay discount hyperbolic model param0.00.00.1-0.0-0.2-0.20.20.2-0.2-0.30.00.0-0.00.4-0.3-0.1-0.00.3
Fecal boli incidents, locomotor time 10.20.20.7-0.3-0.70.3-0.30.6-0.3-0.40.4-0.8-0.40.2-0.2-0.3-0.40.1
Change in fecal boli incidents, locomotor task1.01.02.6-0.9-0.61.1-1.1-1.61.5-0.70.9-0.5-0.90.8-0.8-1.0-0.90.9
Time >=10cm from walls, locomotor time 11.71.73.1-1.4-1.71.7-1.7-0.30.7-1.11.5-1.8-1.50.8-0.9-1.6-1.50.7
Bouts of movement, locomotor time 10.30.31.10.40.3-1.01.10.7-0.7-0.2-0.60.30.60.3-0.20.20.60.2
Total resting periods, locomotor time 10.30.30.90.50.3-1.01.00.8-0.8-0.1-0.60.30.60.1-0.00.30.60.0
Rest time, locomotor task time 11.51.62.0-1.3-1.31.0-1.0-1.01.1-1.41.4-1.3-1.41.4-1.4-1.0-1.41.4
Distance moved, locomotor task time 10.30.30.50.60.5-0.30.30.4-0.40.7-0.60.70.6-0.70.70.40.6-0.7
Vertical activity count, locomotor time 10.60.61.0-0.7-0.80.9-0.9-0.80.8-0.70.8-0.6-0.80.7-0.7-1.0-0.80.7
Time >=10cm from walls, locomotor time 20.10.10.2-0.2-0.50.1-0.10.5-0.3-0.40.2-0.5-0.20.3-0.3-0.2-0.20.2
Bouts of movement, locomotor time 21.31.41.91.21.3-1.41.41.0-1.11.0-1.31.21.3-0.91.01.31.3-1.0
Total resting periods, locomotor time 20.60.71.00.80.8-1.01.00.7-0.80.7-0.80.90.8-0.70.71.00.8-0.7
Rest time, locomotor task time 23.54.05.2-2.0-2.12.1-2.1-1.71.9-2.02.3-2.0-2.31.9-1.9-1.9-2.31.9
Distance moved, locomotor task time 20.60.71.10.80.8-1.11.10.7-0.80.5-1.01.01.0-0.40.50.71.0-0.5
Vertical activity count, locomotor time 20.20.20.5-0.10.0-0.20.2-0.70.5-0.50.10.0-0.10.7-0.6-0.3-0.10.7
Weight adjusted by age1.92.12.61.51.3-1.31.31.6-1.61.5-1.41.31.4-1.51.61.41.4-1.6
Seeking ratio, delayed vs. immediate footshock0.00.00.20.10.10.0-0.0-0.10.00.10.00.5-0.0-0.10.10.1-0.0-0.1
Locomotion in novel chamber1.62.03.3-1.5-1.81.7-1.7-0.50.8-1.31.5-1.7-1.51.0-1.0-1.6-1.50.9
Locomotion in novel chamber post-restriction2.52.94.1-1.9-1.81.7-1.7-1.21.4-1.71.7-2.0-1.71.6-1.6-2.0-1.71.6
Progressive ratio0.00.00.1-0.0-0.00.1-0.10.3-0.30.20.0-0.3-0.0-0.30.30.2-0.0-0.3
Food seeking constrained by brief footshock0.20.20.6-0.4-0.20.3-0.3-0.80.7-0.30.5-0.5-0.50.4-0.4-0.5-0.50.5
Seeking ratio, punishment vs. effort0.20.20.9-0.3-0.00.2-0.2-0.90.8-0.40.2-0.1-0.20.5-0.5-0.4-0.20.6
Run reversals in cocaine runway, females0.60.61.30.71.1-0.30.3-0.40.11.1-0.80.80.8-1.01.00.80.8-0.9
Run reversals in cocaine runway, males0.60.60.8-0.8-0.70.6-0.6-0.70.8-0.90.8-0.6-0.80.9-0.9-0.8-0.80.9
Latency to leave start box in cocaine runway0.30.30.8-0.6-0.60.9-0.9-0.40.5-0.20.6-0.6-0.60.1-0.1-0.4-0.60.1
Latency to leave start box in cocaine runway, F0.00.00.10.00.10.0-0.00.2-0.20.2-0.10.10.1-0.30.30.20.1-0.3
Latency to leave start box in cocaine runway, M3.33.24.1-1.9-1.82.0-2.0-1.61.7-1.61.8-2.0-1.81.5-1.6-1.7-1.81.5
Cd content in liver1.21.34.8-1.1-1.21.1-1.1-0.60.8-1.11.1-2.2-1.11.0-1.0-0.9-1.10.9
Co content in liver2.63.15.4-1.4-1.31.2-1.1-2.32.1-2.01.5-1.3-1.52.3-2.2-1.4-1.52.3
Cu content in liver0.10.20.40.40.6-0.50.5-0.2-0.00.3-0.40.50.4-0.20.20.50.4-0.1
Fe content in liver0.00.00.1-0.1-0.10.0-0.00.3-0.20.1-0.10.20.1-0.20.2-0.10.1-0.2
K content in liver1.41.44.10.91.0-0.70.71.1-1.11.3-1.02.01.0-1.41.40.91.0-1.4
Mg content in liver0.50.61.80.50.5-0.20.20.6-0.61.0-0.51.30.5-1.11.00.40.5-1.0
Mn content in liver2.63.08.51.51.5-1.61.61.7-1.81.6-1.52.91.5-1.61.61.61.5-1.6
Na content in liver0.80.81.30.80.7-0.80.71.1-1.10.9-0.91.10.9-1.01.00.70.9-1.0
Rb content in liver1.82.22.9-1.5-1.31.7-1.7-1.71.7-1.21.5-1.7-1.51.2-1.3-1.5-1.51.3
Se content in liver0.70.82.70.50.3-0.50.51.5-1.30.7-0.51.60.5-0.90.90.50.5-1.0
Sr content in liver6.25.66.52.42.4-2.52.52.3-2.52.2-2.52.02.5-2.22.22.42.5-2.2
Zn content in liver4.75.25.82.32.2-2.22.22.3-2.42.3-2.42.02.4-2.32.42.22.4-2.4