Hub : Genes

Ctsf

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000019708 0.09 0.05 7.6e-07 0.05 0.05 0.03 0.05 1.2e-06 2.3e-06 2.1e-04 2.3e-06
2 BLA gene expression ENSRNOG00000019708 0.67 0.11 0.0e+00 0.52 0.51 0.52 0.51 4.9e-32 2.2e-31 1.8e-32 3.0e-31
3 Brain gene expression ENSRNOG00000019708 0.37 0.03 0.0e+00 0.63 0.65 0.65 0.65 1.2e-75 5.8e-79 3.7e-78 3.9e-78
4 Eye gene expression ENSRNOG00000019708 0.56 0.2 4.8e-04 0.16 0.07 0.11 0.12 2.1e-03 3.2e-02 1.0e-02 6.2e-03
5 IL gene expression ENSRNOG00000019708 0.7 0.13 2.5e-14 0.38 0.19 0.37 -0.01 3.2e-10 2.4e-05 7.9e-10 9.9e-01
6 LHb gene expression ENSRNOG00000019708 0.62 0.15 4.1e-13 0.49 0.24 0.46 0.47 2.4e-13 2.0e-06 2.9e-12 1.5e-12
7 Liver gene expression ENSRNOG00000019708 0.22 0.12 4.5e-11 0.03 0.06 0.07 0.07 1.8e-04 1.0e-07 2.8e-08 8.2e-08
8 NAcc gene expression ENSRNOG00000019708 0.58 0.12 0.0e+00 0.49 0.52 0.52 0.51 7.3e-41 6.5e-45 6.9e-45 1.7e-43
9 OFC gene expression ENSRNOG00000019708 0.57 0.15 1.3e-11 0.36 0.14 0.34 0.1 1.6e-09 4.4e-04 5.7e-09 2.4e-03
10 PL gene expression ENSRNOG00000019708 0.52 0.1 0.0e+00 0.5 0.51 0.5 0.52 1.6e-43 1.8e-44 3.0e-43 3.3e-45

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail0.20.71.3-0.9-0.6-1.1-0.8-0.8-0.81.0-1.0-0.8-0.8
BMI without tail0.00.10.2-0.3-0.0-0.3-0.2-0.2-0.10.4-0.2-0.2-0.1
Body weight1.14.511.02.02.11.52.02.02.03.31.72.02.1
Epididymis fat weight2.25.26.8-2.4-2.3-1.9-2.3-2.3-2.3-2.6-2.1-2.3-2.3
Glucose3.65.65.9-2.4-2.4-2.3-2.3-2.4-2.4-2.3-2.3-2.4-2.4
Heart weight1.82.63.6-1.9-1.7-1.3-1.7-1.4-1.4-1.9-1.6-1.4-1.8
Left kidney weight0.00.10.4-0.5-0.4-0.2-0.3-0.2-0.2-0.6-0.3-0.2-0.4
Right kidney weight0.00.10.30.00.10.30.30.30.20.50.00.30.2
Tail length2.37.08.22.82.72.62.72.72.61.92.82.72.9
Length with tail2.910.711.23.33.33.13.33.33.23.33.13.33.3
Length without tail1.53.35.41.81.81.51.81.81.82.31.61.81.8
Liver weight, left0.10.10.40.10.20.30.10.40.3-0.70.30.40.1
Liver weight, right0.10.10.40.20.30.40.30.40.3-0.60.50.40.3
Parametrial fat weight2.44.87.4-2.7-2.1-1.9-2.1-2.0-2.0-2.1-2.2-2.0-2.5
Retroperitoneal fat weight3.611.916.6-3.5-3.5-3.0-3.3-3.4-3.4-4.1-3.2-3.4-3.6
Intraocular pressure0.00.10.2-0.20.10.40.20.20.20.3-0.20.2-0.1
Extensor digitorum longus weight4.016.228.83.94.13.53.93.93.95.43.53.93.9
Soleus weight1.33.712.3-1.6-1.9-1.6-1.8-1.7-1.7-3.5-1.3-1.7-1.7
Tibialis anterior weight8.930.643.55.45.65.15.55.55.56.65.05.55.5
Tibia length0.72.15.11.41.31.21.41.31.32.31.11.31.5
Number of licking bursts0.10.10.70.20.0-0.10.1-0.0-0.00.8-0.1-0.00.1
Food consumed during 24 hour testing period0.10.10.20.40.20.10.20.20.20.50.10.20.3
Times rat made contact with spout0.00.00.30.20.1-0.10.0-0.0-0.00.50.0-0.00.1
Mean time between licks in bursts0.50.71.21.10.80.60.90.70.70.41.10.71.0
Mean num. licks in bursts0.10.20.6-0.4-0.3-0.3-0.4-0.3-0.3-0.8-0.2-0.3-0.3
Std. dev. time between licks in bursts1.11.32.01.01.21.31.21.21.2-0.51.41.21.1
Water consumed over 24 hours0.20.30.70.50.50.40.60.40.40.90.40.40.5
Indifference point 0 sec0.20.40.5-0.6-0.6-0.6-0.7-0.7-0.6-0.1-0.7-0.7-0.7
Indifference point AUC2.12.43.61.31.71.41.41.71.71.91.21.71.4
Indifference point function ln k2.73.812.3-1.4-1.9-1.5-1.8-1.9-1.8-3.5-1.2-1.9-1.7
Indifference point function log k2.73.812.3-1.4-1.9-1.5-1.8-1.9-1.8-3.5-1.2-1.9-1.7
Delay discounting total patch changes 0 sec0.00.00.00.0-0.0-0.0-0.1-0.10.0-0.0-0.1-0.1-0.1
Delay discounting total patch changes 12 sec1.52.04.91.11.51.11.21.41.52.21.01.41.1
Delay discounting total patch changes 18 sec0.10.10.6-0.30.30.20.00.40.40.8-0.10.4-0.0
Delay discounting total patch changes 24 sec2.02.53.51.31.71.41.61.71.71.91.41.71.5
Delay discounting total patch changes 6 sec0.10.21.10.30.50.30.40.40.41.00.20.40.3
Delay discounting time to switch 0 sec0.30.41.9-0.3-0.3-0.7-0.2-0.5-0.61.4-0.7-0.5-0.3
Delay discounting water rate 0 sec0.20.32.8-0.3-0.30.1-0.3-0.2-0.2-1.70.0-0.2-0.2
Delay discounting water rate 12 sec0.81.29.9-0.5-0.6-0.1-0.5-0.5-0.4-3.20.1-0.5-0.4
Delay discounting water rate 18 sec0.50.63.3-0.5-0.7-0.5-0.6-0.7-0.6-1.8-0.2-0.7-0.6
Delay discounting water rate 24 sec0.30.43.8-0.3-0.30.1-0.2-0.3-0.3-1.90.2-0.3-0.2
Delay discounting water rate 6 sec0.20.32.60.20.10.30.20.20.3-1.60.60.20.2
Locomotor activity0.10.21.20.30.10.30.20.10.2-1.10.60.10.3
Locomotor testing distance0.20.32.20.30.00.20.20.10.1-1.50.60.10.3
Locomotor testing rearing0.60.93.2-1.0-0.9-0.7-0.8-0.9-0.8-1.8-0.6-0.9-0.8
Light reinforcement 10.00.00.3-0.1-0.1-0.00.0-0.1-0.1-0.5-0.1-0.1-0.1
Light reinforcement 20.60.81.1-0.7-1.1-0.9-0.9-1.0-1.0-0.3-1.0-1.0-0.8
Reaction time number correct0.91.31.41.21.21.11.11.21.11.11.11.21.0
Reaction time mean minus median0.91.26.10.70.90.71.10.70.82.50.40.70.9
Reaction time mean minus median AUC1.72.15.21.21.41.31.51.41.42.31.01.41.3
Reaction time num false alarms0.81.11.71.01.01.11.11.11.1-0.41.31.11.1
Reaction time num false alarms AUC1.41.92.61.31.41.51.51.41.40.31.61.41.5
Reaction time trials correct on left0.91.31.41.21.21.11.11.21.11.11.11.21.0
Reaction time trials on left1.11.61.71.31.31.31.21.31.31.21.21.31.2
Reaction time mean0.00.10.2-0.2-0.2-0.1-0.1-0.3-0.30.4-0.3-0.3-0.0
Reaction time mean AUC0.10.20.3-0.4-0.4-0.3-0.3-0.5-0.50.4-0.5-0.5-0.2
Median of all reaction times0.20.30.5-0.5-0.6-0.5-0.5-0.7-0.7-0.2-0.6-0.7-0.4
Reaction time omissions1.41.94.11.21.41.31.41.31.22.01.11.31.3
Reaction time false alarm rate0.30.50.80.60.70.70.80.70.7-0.40.90.70.8
Reaction time premature initiation rate2.33.13.71.81.81.71.91.71.71.51.81.71.9
Reaction time premature initiations4.56.47.12.62.62.42.72.52.42.42.52.52.7
Std. dev. reaction times0.30.42.20.30.50.50.60.30.41.50.10.30.5
Reaction time trials completed1.11.61.71.31.31.31.21.31.31.21.21.31.2
Reaction time trials AUC0.81.21.31.11.11.11.01.11.10.91.11.11.0
Social response proportion0.10.11.0-0.0-0.1-0.30.0-0.2-0.21.0-0.3-0.20.1
Social responses0.30.40.50.40.60.50.70.70.70.60.50.70.7
Social time0.40.50.70.80.70.60.80.80.70.60.70.80.8
Conditioned locomotion2.93.53.81.82.01.81.91.91.91.81.91.91.8
Cocaine response after cond. corrected0.20.21.2-0.3-0.4-0.2-0.3-0.4-0.4-1.1-0.2-0.4-0.4
Cocaine response after cond. not corrected0.40.41.0-0.5-0.6-0.5-0.5-0.6-0.6-1.0-0.5-0.6-0.6
Cocaine response before conditioning0.10.10.7-0.1-0.2-0.3-0.2-0.3-0.30.9-0.4-0.3-0.0
Saline control response1.01.32.81.21.10.81.21.01.01.71.01.01.2
Condit. Reinf. active minus inactive responses1.72.12.6-1.3-1.5-1.6-1.6-1.5-1.5-0.3-1.5-1.5-1.3
Condit. Reinf. active-inactive response ratio2.22.32.8-1.4-1.6-1.7-1.6-1.6-1.6-0.6-1.6-1.6-1.5
Condit. Reinf. active responses1.52.02.7-1.3-1.5-1.6-1.6-1.5-1.5-0.1-1.6-1.5-1.3
Condit. Reinf. inactive responses0.20.30.4-0.7-0.5-0.6-0.6-0.5-0.5-0.0-0.7-0.5-0.5
Condit. Reinf. lever presses0.20.32.80.20.1-0.1-0.10.10.11.7-0.20.10.2
Condit. Reinf. lever reinforcers received1.01.42.0-1.1-1.2-1.4-1.3-1.3-1.20.3-1.4-1.3-1.1
Pavlov. Cond. lever latency0.00.10.6-0.0-0.1-0.0-0.0-0.1-0.1-0.80.2-0.1-0.1
Pavlov. Cond. magazine entry latency0.40.53.30.60.40.10.40.30.31.80.10.30.5
Pavlov. Cond. change in total contacts0.30.52.4-0.3-0.4-0.6-0.4-0.5-0.51.5-0.8-0.5-0.3
Pavlov. Cond. index score0.20.32.60.30.2-0.10.20.10.11.6-0.10.10.3
Pavlov. Cond. latency score0.20.22.20.30.2-0.10.20.10.11.5-0.10.10.3
Pavlov. Cond. lever contacts0.10.20.70.30.40.30.30.40.30.80.10.40.4
Pavlov. Cond. magazine entry number0.81.06.5-0.8-0.7-0.3-0.7-0.5-0.5-2.5-0.3-0.5-0.8
Pavlov. Cond. intertrial magazine entries0.40.51.3-0.7-0.7-0.5-0.7-0.6-0.6-1.1-0.5-0.6-0.6
Pavlov. Cond. lever-magazine prob. diff.0.30.43.10.40.3-0.00.30.20.21.8-0.00.20.4
Pavlov. Cond. response bias0.20.32.10.40.30.10.30.30.31.50.00.30.4
Conditioned reinforcement - actives0.00.00.1-0.1-0.10.0-0.0-0.1-0.3-0.1-0.1-0.1-0.1
Conditioned reinforcement - inactives3.43.84.6-2.0-2.0-1.7-1.9-2.0-2.2-1.9-1.8-2.0-2.0
Conditioned locomotion2.12.57.3-1.5-1.6-1.1-1.5-1.5-1.4-2.7-1.1-1.5-1.5
Intermittent access intake day 1-15 change0.00.00.10.10.10.20.10.30.40.00.10.30.1
Intermittent access intake escalation0.00.00.1-0.3-0.2-0.1-0.2-0.00.1-0.2-0.1-0.0-0.2
Intermittent access intake escalation 20.20.20.20.40.40.50.40.50.50.10.40.50.4
Intermitt. access day 1 inactive lever presses1.71.92.3-1.4-1.5-1.3-1.4-1.4-1.3-1.0-1.4-1.4-1.4
Intermitt. access day 15 inactive lever presses1.41.61.9-1.2-1.4-1.2-1.3-1.3-1.2-0.9-1.3-1.3-1.4
Intermitt. access escalation Index3.63.26.1-1.9-1.8-1.6-1.8-1.6-1.6-2.5-1.4-1.6-1.8
Intermittent access day 1 total infusions10.211.513.5-3.5-3.5-3.2-3.4-3.5-3.7-2.8-3.3-3.5-3.4
Intermittent access day 15 total infusions6.87.68.5-2.9-2.9-2.5-2.8-2.8-2.8-2.5-2.7-2.8-2.8
Intermittent access terminal intake (last 3 days)6.06.67.4-2.7-2.7-2.4-2.6-2.6-2.7-2.0-2.6-2.6-2.6
Intermittent access total infusions7.27.99.0-3.0-2.9-2.7-2.8-2.9-3.0-2.0-2.8-2.9-2.9
Intermittent access day 1 locomotion7.57.78.7-2.9-2.8-2.7-2.8-2.9-3.0-2.2-2.7-2.9-2.8
Intermittent access day 15 total locomotion5.05.36.3-2.5-2.4-2.1-2.3-2.4-2.4-1.9-2.2-2.4-2.3
Intermittent access total locomotion10.812.213.5-3.7-3.6-3.4-3.5-3.6-3.6-2.7-3.4-3.6-3.6
Intermittent access standard deviation0.20.20.4-0.5-0.4-0.3-0.4-0.3-0.3-0.7-0.3-0.3-0.4
Cocaine induced anxiety0.10.10.10.20.20.30.30.20.20.30.20.20.3
Post-drug Anxiety1.71.92.71.41.41.41.41.41.41.61.21.41.4
Baseline Anxiety2.22.32.61.61.61.41.61.61.61.51.41.61.6
Lifetime Intake6.57.38.4-2.9-2.8-2.6-2.7-2.8-2.9-2.1-2.7-2.8-2.8
Incentive Sensitization - Responses0.90.91.1-0.9-1.0-1.0-1.0-1.1-1.1-0.3-1.1-1.1-1.0
Incentive Sensitization - Breakpoint1.01.01.3-0.9-1.1-1.0-1.0-1.1-1.1-0.5-1.1-1.1-1.0
Progressive ratio test 1 active lever presses2.22.22.9-1.5-1.5-1.3-1.4-1.6-1.7-1.5-1.4-1.6-1.4
Progressive ratio test 1 breakpoint1.61.72.2-1.3-1.3-1.0-1.2-1.4-1.5-1.4-1.2-1.4-1.2
Progressive ratio test 1 inactive lever presses1.21.31.6-1.1-1.2-1.1-1.2-1.2-1.3-1.2-1.0-1.2-1.2
Progressive ratio test 2 active lever presses3.94.15.3-2.0-2.1-1.8-2.0-2.2-2.3-1.7-2.0-2.2-2.0
Progressive ratio test 2 breakpoint3.13.54.4-1.8-1.9-1.6-1.8-2.0-2.1-1.9-1.7-2.0-1.8
Progressive ratio test 2 inactive lever presses8.49.811.7-3.1-3.2-2.9-3.2-3.2-3.4-2.9-2.9-3.2-3.1
Total sessions with >9 infusions2.12.33.0-1.7-1.6-1.4-1.6-1.5-1.5-1.4-1.4-1.5-1.6
Short access day 1 total inactive lever presses3.33.75.9-1.9-2.0-1.7-1.9-1.8-1.9-2.4-1.7-1.8-1.9
Short access day 10 total inactive lever presses1.01.13.1-0.9-1.1-0.8-1.0-1.0-0.9-1.8-0.8-1.0-1.0
Short access day 1 total infusions5.96.37.0-2.6-2.6-2.4-2.6-2.5-2.6-2.1-2.5-2.5-2.6
Short access day 10 total infusions6.77.48.7-2.9-2.8-2.7-2.8-2.8-2.8-1.6-2.8-2.8-2.8
Short access total infusions3.53.94.7-2.2-2.0-1.9-2.0-2.0-2.1-1.6-1.9-2.0-2.0
Short access day 1 locomotion4.75.05.5-2.3-2.3-2.2-2.3-2.3-2.3-1.6-2.2-2.3-2.3
Short access day 10 total locomotion4.04.44.9-2.2-2.1-2.1-2.2-2.1-2.0-1.6-2.0-2.1-2.2
Short access total locomotion3.73.84.1-2.0-2.0-1.9-2.0-2.0-2.0-1.5-1.9-2.0-2.0
Compulsive drug intake4.24.25.02.22.21.92.12.12.01.32.22.12.1
One hour access (0.3 mA shock)6.17.18.0-2.6-2.8-2.4-2.6-2.8-2.8-2.8-2.4-2.8-2.7
One hour access (shock baseline)7.28.49.6-3.0-3.1-2.7-2.9-3.0-3.0-2.3-2.9-3.0-3.0
Number of responses in last shaping day0.20.21.0-0.4-0.3-0.0-0.3-0.2-0.4-1.0-0.2-0.2-0.2
Context. condit. distance diff. score0.91.13.1-1.1-1.0-0.8-0.8-0.9-0.9-1.8-0.8-0.9-1.0
Locomotion velocity, session 10.30.30.60.80.40.40.60.40.40.10.80.40.8
Locomotion distance, session 10.30.40.9-0.4-0.6-0.9-0.6-0.7-0.80.3-0.5-0.7-0.4
Locomotion velocity, session 20.70.92.20.90.90.60.90.80.81.50.80.80.9
Locomotion distance, session 20.00.10.30.2-0.0-0.30.0-0.1-0.10.60.2-0.10.2
Locomotion velocity, session 30.40.40.6-0.7-0.7-0.8-0.6-0.7-0.7-0.7-0.6-0.7-0.6
Locomotion distance, session 30.00.00.0-0.2-0.1-0.10.1-0.0-0.0-0.2-0.0-0.0-0.1
Stereotopy head waving bouts, day 30.81.01.9-1.0-0.9-0.9-1.0-0.9-0.9-1.4-0.8-0.9-1.0
Stereotopy head waving duration, day 31.31.61.9-1.2-1.3-1.2-1.3-1.3-1.3-1.4-1.1-1.3-1.2
Locomotion velocity, session 70.91.01.4-1.2-0.9-0.9-0.9-0.9-0.9-1.1-0.9-0.9-1.0
Locomotion distance, session 70.00.00.4-0.10.00.0-0.00.00.0-0.60.10.0-0.1
Stereotopy head waving bouts, day 71.31.42.1-1.4-1.2-1.1-1.2-1.2-1.2-0.4-1.4-1.2-1.3
Stereotopy head waving duration, day 70.40.51.0-0.9-0.6-0.7-0.6-0.6-0.60.8-1.0-0.6-0.7
Locomotion velocity, session 81.11.31.61.21.21.01.31.11.11.01.21.11.3
Locomotion distance, session 80.30.50.7-0.6-0.7-0.8-0.6-0.8-0.8-0.6-0.5-0.8-0.5
Degree of sensitization distance0.10.10.3-0.3-0.2-0.2-0.4-0.3-0.3-0.5-0.2-0.3-0.3
Degree of sensitization stereotypy0.20.30.6-0.7-0.3-0.3-0.4-0.3-0.30.7-0.8-0.3-0.5
Condit. Reinf. active minus inactive responses0.10.20.30.1-0.4-0.5-0.4-0.4-0.40.5-0.3-0.4-0.1
Condit. Reinf. active-inactive response ratio0.20.20.3-0.1-0.5-0.6-0.5-0.5-0.50.5-0.4-0.5-0.3
Condit. Reinf. active responses0.10.10.30.1-0.2-0.3-0.2-0.3-0.30.5-0.2-0.3-0.0
Condit. Reinf. inactive responses0.00.00.0-0.2-0.2-0.1-0.0-0.2-0.2-0.1-0.2-0.2-0.1
Incentive salience index mean0.10.10.40.1-0.3-0.5-0.3-0.4-0.40.6-0.2-0.4-0.1
Condit. Reinf. lever presses0.10.10.90.50.20.10.20.10.11.00.20.10.4
Time in familiar zone, hab. session 10.90.91.1-0.8-1.0-1.0-1.0-1.0-1.0-0.6-1.0-1.0-0.9
Time in novel zone, hab. session 10.40.40.70.60.60.70.60.60.6-0.40.80.60.6
Total zone transitions, hab. session 10.20.31.20.50.40.20.40.30.31.10.40.30.6
Total locomotion distance, hab. session 10.30.50.5-0.6-0.7-0.7-0.7-0.7-0.7-0.7-0.6-0.7-0.6
Locomotion velocity, hab. session 10.10.10.2-0.2-0.4-0.4-0.3-0.4-0.4-0.2-0.3-0.4-0.2
Time in familiar zone, hab. session 20.80.91.20.91.01.01.01.01.0-0.11.11.00.9
Time in novel zone, hab. session 20.80.81.0-0.9-0.9-0.9-1.0-0.9-0.9-0.0-1.0-0.9-0.9
Total zone transitions, hab. session 21.11.42.3-1.1-1.1-1.5-1.2-1.3-1.30.5-1.2-1.3-1.1
Total locomotion distance, hab. session 21.21.52.0-1.2-1.3-1.4-1.3-1.3-1.3-0.6-1.2-1.3-1.2
Locomotion velocity, hab. session 21.52.02.6-1.4-1.5-1.6-1.5-1.5-1.5-0.6-1.4-1.5-1.4
Novel to familiar place preference ratio0.20.31.0-0.4-0.3-0.4-0.3-0.4-0.41.0-0.7-0.4-0.3
Novelty place preference0.40.40.9-0.7-0.6-0.6-0.5-0.6-0.60.6-0.9-0.6-0.6
Time in novel zone, NPP test0.40.40.8-0.7-0.6-0.6-0.6-0.6-0.60.4-0.9-0.6-0.6
Total zone transitions, NPP test0.20.22.10.40.1-0.20.1-0.0-0.01.40.1-0.00.4
Total locomotion distance, NPP test0.10.20.4-0.2-0.4-0.6-0.5-0.5-0.5-0.0-0.3-0.5-0.2
Locomotion velocity, NPP test0.10.10.3-0.1-0.4-0.5-0.4-0.4-0.40.1-0.2-0.4-0.1
Pavlov. Cond. lever latency0.00.00.2-0.0-0.0-0.0-0.0-0.0-0.0-0.40.0-0.0-0.1
Pavlov. Cond. magazine entry latency0.91.11.4-1.0-1.1-1.2-1.2-1.1-1.10.2-1.2-1.1-1.1
Pavlov. Cond. change in total contacts0.70.81.1-0.7-0.9-0.9-0.9-0.9-0.90.5-1.1-0.9-0.8
Pavlov. Cond. index score0.10.10.3-0.1-0.3-0.2-0.3-0.2-0.20.5-0.3-0.2-0.2
Pavlov. Cond. latency score0.10.10.2-0.2-0.4-0.3-0.4-0.3-0.30.2-0.4-0.3-0.3
Pavlov. Cond. lever contacts0.00.00.00.0-0.1-0.0-0.1-0.1-0.10.1-0.1-0.10.0
Pavlov. Cond. magazine entry number0.10.10.8-0.10.00.00.10.00.0-0.90.20.00.0
Pavlov. Cond. intertrial magazine entries0.00.00.0-0.10.10.20.10.10.1-0.20.00.10.1
Pavlov. Cond. lever-magazine prob. diff.0.10.10.50.0-0.2-0.2-0.2-0.2-0.20.7-0.3-0.2-0.1
Pavlov. Cond. response bias0.10.10.50.1-0.1-0.1-0.1-0.1-0.10.7-0.2-0.1-0.0
Bone: apparent density1.32.22.9-1.5-1.5-1.6-1.6-1.5-1.50.0-1.7-1.5-1.5
Bone surface0.40.84.9-0.4-0.4-0.7-0.5-0.5-0.52.2-0.8-0.5-0.4
Bone volume0.81.42.1-1.1-1.1-1.3-1.1-1.2-1.21.1-1.5-1.2-1.1
Bone: connectivity density0.50.71.6-0.8-0.6-1.0-0.7-0.7-0.71.2-1.0-0.7-0.7
Bone: cortical apparent density0.50.70.90.70.90.80.90.90.90.70.80.90.8
Bone: cortical area0.81.22.01.01.11.01.01.11.11.40.91.11.1
Bone: cortical porosity0.30.30.5-0.5-0.6-0.7-0.7-0.6-0.6-0.3-0.6-0.6-0.6
Bone: cortical porosity0.00.00.0-0.1-0.0-0.2-0.2-0.1-0.10.1-0.1-0.1-0.1
Bone: cortical thickness5.89.710.43.03.23.13.13.23.22.93.03.23.0
Bone: cortical thickness3.74.44.92.02.22.22.22.22.21.22.22.22.0
Bone: cortical tissue density0.70.91.10.81.01.01.01.01.00.80.91.00.9
Bone: elastic displacement1.01.11.81.01.01.21.11.11.1-0.31.31.11.0
Bone: elastic work3.24.14.81.92.12.02.12.12.11.22.22.12.0
Bone: endosteal estimation2.65.76.3-2.2-2.5-2.5-2.5-2.5-2.5-2.0-2.3-2.5-2.3
Bone: endosteal perimeter4.79.711.5-2.9-3.3-3.4-3.2-3.3-3.3-1.9-3.2-3.3-3.0
Bone: final force0.81.33.61.11.10.81.01.01.01.90.91.01.1
Bone: final moment0.61.03.21.01.00.70.90.90.91.80.80.91.1
Bone: marrow area2.75.76.4-2.3-2.5-2.5-2.5-2.5-2.5-2.0-2.3-2.5-2.3
Bone: maximum diameter0.00.10.60.1-0.1-0.2-0.1-0.1-0.10.8-0.2-0.10.1
Bone: maximum force0.20.44.10.20.1-0.30.0-0.0-0.02.0-0.2-0.00.2
Bone: maximum moment0.20.43.40.20.1-0.3-0.0-0.0-0.01.8-0.2-0.00.2
Bone: minimum diameter3.15.76.4-2.5-2.4-2.5-2.5-2.5-2.5-1.8-2.4-2.5-2.4
Bone: periosteal estimation0.20.40.5-0.6-0.7-0.7-0.7-0.7-0.7-0.2-0.7-0.7-0.6
Bone: periosteal perimeter0.40.60.9-0.7-0.8-0.9-0.8-0.9-0.90.2-0.9-0.9-0.7
Bone: post-yield work7.19.712.6-2.9-3.2-3.6-3.3-3.3-3.3-0.1-3.5-3.3-3.1
Bone: stiffness0.30.42.6-0.3-0.3-0.7-0.4-0.4-0.41.6-0.7-0.4-0.2
Bone: tissue strength0.40.40.6-0.4-0.7-0.8-0.6-0.7-0.70.2-0.7-0.7-0.5
Bone: trabecular number1.11.72.5-1.4-1.2-1.4-1.3-1.3-1.30.5-1.6-1.3-1.3
Bone: trabecular spacing0.10.10.30.40.30.30.40.30.3-0.50.50.30.4
Bone: trabecular thickness2.12.52.8-1.6-1.6-1.6-1.7-1.6-1.6-1.0-1.7-1.6-1.6
Bone: trabecular tissue density0.81.13.8-0.8-1.0-0.9-1.0-1.0-1.0-1.9-0.7-1.0-0.9
Breakpoint value in progressive ratio session1.31.54.31.11.21.01.21.11.12.10.81.11.2
Distance traveled before self-admin0.10.10.30.20.20.10.30.1-0.10.60.00.10.2
Distance traveled after self-admin0.00.00.20.1-0.0-0.10.1-0.1-0.30.4-0.1-0.10.1
Delta time in closed arm before/after self-admin1.11.01.40.81.11.21.01.11.1-0.21.21.11.0
Delta time in open arm before/after self-admin0.00.00.2-0.0-0.10.1-0.00.0-0.10.5-0.30.00.0
Diff in mean of infusions in LGA sessions0.80.81.20.71.01.00.90.91.11.10.70.90.9
Extinction: sum of active levers before priming0.90.94.00.70.90.60.80.80.72.00.50.80.8
Active lever presses in extinction session 62.72.63.61.71.61.51.51.61.61.91.31.61.6
Delta distance traveled before/after self-admin0.00.00.00.10.10.10.00.10.1-0.10.10.10.1
Delta ambulatory time before/after self-admin0.10.10.10.20.30.30.20.30.3-0.10.30.30.3
Time in closed arm before self-admin0.40.40.6-0.3-0.7-0.8-0.6-0.7-0.70.3-0.7-0.7-0.6
Time in closed arm after self-admin0.00.00.00.1-0.00.00.0-0.0-0.10.00.1-0.00.0
Time in open arm before self-admin0.20.21.10.20.30.30.30.20.1-1.10.60.20.2
Time in open arm after self-admin0.10.10.30.20.30.50.40.40.2-0.30.30.40.4
Sum of active levers in priming session hrs 5-62.72.75.11.51.61.61.61.71.62.21.31.71.6
Time to tail flick, vehicle, before self-admin0.00.00.2-0.1-0.1-0.2-0.1-0.1-0.20.4-0.1-0.1-0.1
Time to tail flick, vehicle, after self-admin0.30.30.40.70.60.40.50.50.40.60.50.50.6
Time to tail flick, test, before self-admin1.41.31.6-1.1-1.2-1.2-1.1-1.2-1.2-1.3-0.9-1.2-1.1
Time to tail flick, test, after self-admin0.00.00.2-0.00.10.10.10.1-0.00.40.10.10.2
Delta time to tail flick, vehicle, before/after SA0.10.10.10.40.20.10.20.10.20.40.20.10.2
Delta time to tail flick, test, before/after SA3.83.43.81.81.91.91.81.81.81.91.61.81.9
Ambulatory time before self-admin0.10.10.6-0.2-0.2-0.2-0.0-0.3-0.50.8-0.4-0.3-0.1
Ambulatory time after self-admin1.31.42.3-1.1-1.2-1.2-1.1-1.3-1.5-0.2-1.3-1.3-1.2
Total heroin consumption2.73.25.91.61.81.51.91.81.72.41.31.81.8
Area under the delay curve1.01.01.6-0.8-0.9-1.1-0.8-1.2-1.3-0.9-0.8-1.2-0.9
Delay disc. indifference point, 0s delay1.01.13.3-0.9-1.0-1.0-0.9-0.9-1.0-1.8-0.6-0.9-1.0
Delay disc. indifference point, 16s delay2.52.53.2-1.5-1.7-1.7-1.6-1.7-1.8-0.7-1.6-1.7-1.6
Delay disc. indifference point, 2s delay0.40.50.8-0.5-0.7-0.7-0.6-0.8-0.9-0.7-0.6-0.8-0.6
Delay disc. indifference point, 24s delay0.20.20.30.60.50.40.60.1-0.0-0.20.60.10.4
Delay disc. indifference point, 4s delay0.40.41.2-0.5-0.5-0.6-0.4-0.6-0.5-1.1-0.4-0.6-0.6
Delay disc. indifference point, 8s delay0.30.30.7-0.4-0.4-0.6-0.3-0.7-0.7-0.8-0.2-0.7-0.4
Delay discount exponential model param0.70.71.20.60.70.90.61.11.10.70.61.10.7
Delay discount hyperbolic model param0.50.61.00.50.70.80.61.01.00.70.61.00.6
Fecal boli incidents, locomotor time 10.10.10.8-0.2-0.10.1-0.10.10.30.9-0.40.1-0.2
Change in fecal boli incidents, locomotor task0.10.10.4-0.1-0.2-0.4-0.1-0.4-0.5-0.70.1-0.4-0.2
Time >=10cm from walls, locomotor time 14.84.86.1-2.1-2.3-2.3-2.3-2.5-2.4-0.6-2.2-2.5-2.2
Bouts of movement, locomotor time 10.50.63.10.60.60.50.50.60.71.80.40.60.5
Total resting periods, locomotor time 10.30.32.60.30.20.10.20.20.31.60.00.20.2
Rest time, locomotor task time 10.40.40.6-0.4-0.7-0.5-0.6-0.7-0.6-0.8-0.5-0.7-0.6
Distance moved, locomotor task time 10.20.30.4-0.6-0.5-0.6-0.7-0.4-0.5-0.3-0.5-0.4-0.6
Vertical activity count, locomotor time 10.30.30.9-0.7-0.4-0.3-0.5-0.3-0.4-1.0-0.3-0.3-0.6
Time >=10cm from walls, locomotor time 20.20.20.3-0.3-0.5-0.5-0.4-0.5-0.60.3-0.4-0.5-0.4
Bouts of movement, locomotor time 20.20.20.90.30.40.40.50.30.41.00.30.30.4
Total resting periods, locomotor time 20.00.00.4-0.00.10.10.2-0.00.10.7-0.0-0.00.1
Rest time, locomotor task time 21.21.42.9-1.0-1.1-0.9-1.1-1.2-1.0-1.7-0.9-1.2-1.1
Distance moved, locomotor task time 20.60.71.20.80.80.60.70.90.71.10.80.90.8
Vertical activity count, locomotor time 21.71.92.41.31.51.41.51.51.40.31.51.51.4
Weight adjusted by age1.82.03.81.31.51.21.41.31.41.91.31.31.3
Seeking ratio, delayed vs. immediate footshock0.70.81.2-0.7-0.9-1.0-0.8-1.1-1.1-0.4-0.7-1.1-0.7
Locomotion in novel chamber2.93.64.2-1.8-2.1-1.8-1.9-2.0-2.0-1.9-1.6-2.0-1.9
Locomotion in novel chamber post-restriction1.31.63.5-1.2-1.3-1.0-1.2-1.1-1.2-1.9-1.1-1.1-1.2
Progressive ratio0.40.50.8-0.7-0.6-0.9-0.7-0.6-0.60.7-0.9-0.6-0.7
Food seeking constrained by brief footshock0.50.60.80.80.80.80.80.90.90.40.90.90.8
Seeking ratio, punishment vs. effort0.50.61.10.70.70.80.70.60.6-0.91.00.60.8
Run reversals in cocaine runway, females0.00.00.1-0.1-0.1-0.3-0.2-0.1-0.1-0.0-0.0-0.1-0.1
Run reversals in cocaine runway, males2.22.13.01.41.51.71.61.51.50.31.61.51.5
Latency to leave start box in cocaine runway0.91.01.3-0.9-1.1-1.1-1.0-1.1-1.1-0.2-1.1-1.1-0.9
Latency to leave start box in cocaine runway, F0.40.40.6-0.5-0.7-0.8-0.6-0.7-0.7-0.1-0.7-0.7-0.6
Latency to leave start box in cocaine runway, M0.10.10.1-0.2-0.2-0.3-0.2-0.3-0.30.1-0.3-0.3-0.2
Cd content in liver0.30.30.9-0.5-0.5-0.3-0.6-0.4-0.4-1.0-0.4-0.4-0.6
Co content in liver0.70.82.00.60.81.00.80.80.8-1.41.10.80.7
Cu content in liver0.00.00.1-0.00.20.1-0.00.20.10.30.00.20.1
Fe content in liver0.20.20.40.40.50.50.60.40.50.60.40.40.5
K content in liver0.10.10.9-0.1-0.1-0.4-0.2-0.2-0.20.9-0.3-0.20.0
Mg content in liver2.42.53.2-1.6-1.6-1.8-1.7-1.7-1.7-0.4-1.7-1.7-1.5
Mn content in liver0.80.95.00.60.70.60.80.70.72.20.40.70.8
Na content in liver0.91.02.01.10.90.81.00.90.91.40.90.91.1
Rb content in liver2.93.65.5-1.9-1.8-1.7-2.0-1.8-1.8-2.3-1.7-1.8-2.0
Se content in liver0.91.11.6-1.2-1.1-1.1-1.1-1.1-1.10.2-1.3-1.1-1.1
Sr content in liver3.43.13.61.71.81.81.71.81.81.91.51.81.7
Zn content in liver0.30.31.20.50.60.40.30.60.51.10.40.60.4