Hub : Genes

Ubxn1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio ENSRNOT00000026651 0.04 0.03 3.1e-04 0.01 0.02 0.02 0.01 1.4e-02 4.2e-03 6.5e-03 1.4e-02
2 Adipose isoform ratio ENSRNOT00000104307 0.04 0.03 4.0e-04 0.01 0.02 0.02 0.01 1.2e-02 5.1e-03 5.8e-03 1.6e-02
3 Adipose intron excision ratio chr1:205746703:205758646 0.15 0.07 6.1e-11 0.08 0.09 0.09 0.08 2.4e-09 4.5e-10 9.5e-10 1.7e-09
4 Adipose intron excision ratio chr1:205749477:205758646 0.05 0.03 2.0e-03 0.02 0.03 0.03 0.02 3.0e-03 6.7e-04 5.4e-04 1.1e-03
5 Adipose intron excision ratio chr1:205758779:205765430 0.07 0.04 1.0e-04 0.03 0.02 0.02 0.02 8.4e-04 1.7e-03 1.2e-03 1.5e-03
6 Adipose intron excision ratio chr1:205765344:205765430 0.16 0.08 7.1e-10 0.06 0.07 0.07 0.06 5.8e-07 1.5e-08 7.6e-08 1.1e-07
7 BLA gene expression ENSRNOG00000019666 0.1 0.06 7.3e-05 0.07 0.08 0.07 0.07 1.7e-04 6.5e-05 1.1e-04 1.2e-04
8 BLA mRNA stability ENSRNOG00000019666 0.08 0.05 4.8e-05 0.08 0.06 0.06 0.07 3.5e-05 3.3e-04 2.8e-04 2.0e-04
9 Brain gene expression ENSRNOG00000019666 0.04 0.03 7.2e-04 0.03 0.03 0.03 0.03 1.2e-03 5.3e-04 6.2e-04 4.4e-04
10 Brain mRNA stability ENSRNOG00000019666 0.06 0.04 7.6e-06 0.07 0.06 0.06 0.07 1.7e-07 1.4e-06 1.2e-06 2.1e-07
11 NAcc gene expression ENSRNOG00000019666 0.09 0.07 1.5e-05 0.06 0.06 0.05 0.05 5.9e-05 6.2e-05 2.1e-04 1.6e-04
12 NAcc mRNA stability ENSRNOG00000019666 0.06 0.04 7.5e-05 0.06 0.04 0.05 0.06 1.7e-05 6.5e-04 2.5e-04 1.8e-05
13 PL gene expression ENSRNOG00000019666 0.04 0.02 9.7e-04 0.05 0.04 0.04 0.04 1.8e-04 2.7e-04 3.4e-04 3.2e-04
14 PL mRNA stability ENSRNOG00000019666 0.07 0.04 3.7e-06 0.08 0.07 0.07 0.07 1.9e-06 3.3e-06 3.2e-06 4.7e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail1.44.57.9-2.02.01.8-2.5-0.10.1-1.5-2.6-1.4-2.6-2.5-2.5-2.8-2.6
BMI without tail0.71.42.3-1.21.20.2-0.5-0.80.9-1.0-1.4-1.1-1.5-1.4-1.4-1.5-1.4
Body weight2.510.717.9-3.73.71.6-2.1-0.31.4-3.4-3.8-3.4-4.0-3.8-3.7-4.2-3.8
Epididymis fat weight0.41.02.61.2-1.2-0.0-0.3-0.2-0.71.40.91.61.11.01.10.61.1
Glucose2.64.06.22.3-2.3-0.40.20.1-1.32.52.32.52.22.32.32.02.3
Heart weight1.01.52.01.3-1.3-1.41.0-1.40.51.41.11.20.91.31.31.21.2
Left kidney weight0.10.31.4-0.00.00.9-1.20.8-0.90.1-0.10.3-0.0-0.1-0.1-0.3-0.1
Right kidney weight0.30.93.6-0.40.41.7-1.91.6-1.5-0.1-0.3-0.1-0.4-0.4-0.4-0.5-0.4
Tail length0.92.75.1-1.91.9-0.40.6-0.71.8-2.1-1.5-2.3-1.8-1.6-1.6-1.7-1.6
Length with tail1.86.710.3-3.13.10.9-1.0-0.01.3-3.1-2.9-3.1-3.1-2.8-2.8-3.2-2.8
Length without tail1.53.35.4-2.02.01.2-1.50.50.3-1.9-2.0-2.0-2.2-2.0-2.0-2.3-2.0
Liver weight, left0.30.50.90.7-0.7-0.80.8-0.60.30.61.00.50.60.90.80.70.9
Liver weight, right0.10.10.60.2-0.2-0.40.1-0.80.40.30.30.2-0.10.20.2-0.00.2
Parametrial fat weight1.42.85.22.0-2.00.4-0.50.6-1.72.21.82.31.71.71.71.61.8
Retroperitoneal fat weight2.27.312.03.3-3.3-1.20.9-0.7-1.13.53.23.32.73.13.12.83.2
Intraocular pressure0.10.10.30.1-0.10.00.20.4-0.30.00.40.30.50.40.50.20.4
Extensor digitorum longus weight4.919.629.8-5.15.12.4-2.80.21.5-4.8-5.0-4.8-5.3-5.0-5.1-5.5-5.1
Soleus weight2.16.29.23.0-3.0-1.71.7-0.8-0.42.92.82.62.62.82.83.02.8
Tibialis anterior weight8.228.237.7-6.16.13.2-3.31.21.2-5.9-6.1-6.0-6.1-6.1-6.1-6.1-6.1
Tibia length2.05.511.7-2.02.03.4-3.32.9-2.0-1.8-2.3-1.4-1.5-2.3-2.3-2.3-2.3
Number of licking bursts0.00.00.10.1-0.1-0.0-0.10.1-0.10.10.1-0.2-0.20.1-0.3-0.10.1
Food consumed during 24 hour testing period0.10.20.70.3-0.30.3-0.30.6-0.50.20.30.40.50.40.80.10.3
Times rat made contact with spout0.40.51.6-0.40.4-1.01.0-0.91.3-0.6-0.4-0.9-0.7-0.4-0.3-0.3-0.4
Mean time between licks in bursts1.11.55.8-0.80.8-1.61.3-2.22.4-1.0-0.6-1.0-1.0-0.70.0-0.9-0.6
Mean num. licks in bursts0.20.20.7-0.00.0-0.70.9-0.60.7-0.10.1-0.10.10.10.50.20.1
Std. dev. time between licks in bursts0.81.03.40.4-0.4-1.81.6-1.81.70.30.60.20.20.50.30.40.6
Water consumed over 24 hours0.50.51.0-0.80.8-0.30.3-0.40.9-0.9-0.6-1.0-0.9-0.6-0.9-0.8-0.6
Indifference point 0 sec0.50.92.8-0.90.90.3-0.4-0.10.4-0.9-1.1-1.1-1.1-1.0-1.7-0.9-1.1
Indifference point AUC2.52.95.4-1.81.82.3-2.12.1-1.1-1.7-1.7-1.3-1.2-1.6-1.3-1.8-1.7
Indifference point function ln k4.46.211.72.5-2.5-3.43.0-3.41.92.52.41.81.52.31.82.52.4
Indifference point function log k4.46.211.72.5-2.5-3.43.0-3.41.92.52.41.81.52.31.82.52.4
Delay discounting total patch changes 0 sec0.60.92.0-1.01.0-0.20.2-0.61.0-1.0-1.1-1.3-1.2-0.9-1.4-0.9-1.0
Delay discounting total patch changes 12 sec5.97.810.9-3.23.22.1-2.01.30.1-3.2-3.1-3.1-3.0-3.1-3.3-3.0-3.2
Delay discounting total patch changes 18 sec0.60.71.0-1.01.00.9-0.80.9-0.3-1.0-1.0-0.9-0.8-0.9-0.4-0.7-1.0
Delay discounting total patch changes 24 sec5.67.111.3-3.13.11.6-1.90.50.7-3.0-3.2-3.2-3.4-3.0-2.1-3.1-3.1
Delay discounting total patch changes 6 sec1.01.52.7-1.31.30.5-0.6-0.10.5-1.3-1.5-1.5-1.5-1.3-1.6-1.3-1.4
Delay discounting time to switch 0 sec0.60.92.7-0.50.51.6-1.61.1-1.1-0.3-0.9-0.1-0.4-0.9-1.0-0.6-0.9
Delay discounting water rate 0 sec0.40.71.80.7-0.7-1.31.3-0.90.80.60.90.30.50.90.20.80.9
Delay discounting water rate 12 sec2.43.68.51.7-1.7-2.92.7-2.51.81.41.90.91.01.81.91.61.8
Delay discounting water rate 18 sec1.82.47.91.1-1.1-2.62.3-2.82.11.01.00.40.21.11.11.01.0
Delay discounting water rate 24 sec1.41.93.91.4-1.4-2.01.9-1.61.11.21.30.90.91.41.01.51.3
Delay discounting water rate 6 sec1.82.66.61.3-1.4-2.62.4-2.21.71.21.40.60.71.41.71.31.4
Locomotor activity1.32.16.61.0-1.0-2.62.4-2.21.90.81.20.40.61.20.51.11.2
Locomotor testing distance1.83.09.41.1-1.1-3.12.9-2.92.30.91.20.50.61.30.61.31.2
Locomotor testing rearing1.32.04.71.3-1.3-2.22.1-1.91.41.11.11.01.11.31.11.31.2
Light reinforcement 10.00.10.30.3-0.3-0.50.5-0.10.20.10.20.20.40.3-0.00.30.3
Light reinforcement 21.21.65.90.5-0.52.0-1.92.3-2.40.70.21.21.00.40.70.30.3
Reaction time number correct0.50.71.6-0.90.9-0.50.4-0.81.3-1.0-0.7-1.1-0.9-0.60.4-1.1-0.7
Reaction time mean minus median1.11.56.0-0.80.82.1-1.72.4-1.8-0.8-0.7-0.20.1-0.6-0.3-0.7-0.8
Reaction time mean minus median AUC0.40.42.2-0.60.61.0-0.61.5-0.8-0.7-0.4-0.30.1-0.20.2-0.4-0.4
Reaction time num false alarms1.01.44.90.4-0.4-2.22.2-2.11.90.20.5-0.10.10.4-0.20.70.5
Reaction time num false alarms AUC1.11.55.2-0.30.3-2.12.1-2.12.3-0.5-0.0-0.8-0.6-0.1-0.80.2-0.1
Reaction time trials correct on left0.50.71.6-0.90.9-0.50.4-0.81.3-1.0-0.7-1.1-0.9-0.60.4-1.1-0.7
Reaction time trials on left0.50.71.7-0.90.9-0.50.4-0.81.3-1.0-0.7-1.1-0.9-0.60.4-1.1-0.7
Reaction time mean0.40.52.40.00.01.2-0.91.6-1.3-0.00.10.50.70.00.10.3-0.0
Reaction time mean AUC0.40.62.40.2-0.21.2-0.81.5-1.40.10.20.70.90.20.20.30.1
Median of all reaction times0.20.31.1-0.10.11.0-0.81.1-0.9-0.1-0.10.30.4-0.2-0.10.1-0.2
Reaction time omissions0.10.10.5-0.50.5-0.10.30.30.3-0.7-0.3-0.7-0.2-0.2-0.0-0.1-0.3
Reaction time false alarm rate0.50.82.50.4-0.4-1.61.6-1.51.20.30.50.00.10.3-0.80.80.4
Reaction time premature initiation rate2.93.96.2-2.22.2-0.2-0.1-1.52.1-2.2-2.3-2.2-2.5-2.3-1.3-2.4-2.3
Reaction time premature initiations4.05.68.5-2.72.7-0.50.2-1.72.7-2.8-2.6-2.8-2.9-2.5-1.2-2.9-2.6
Std. dev. reaction times0.40.53.2-0.00.11.1-0.71.8-1.3-0.20.10.30.70.20.00.30.1
Reaction time trials completed0.50.71.7-0.90.9-0.50.4-0.81.3-1.0-0.7-1.1-0.9-0.60.4-1.1-0.7
Reaction time trials AUC0.40.61.7-0.80.8-0.60.5-0.91.3-0.9-0.6-1.0-0.8-0.50.5-1.0-0.6
Social response proportion0.30.32.3-0.30.3-0.20.1-0.40.5-0.3-0.5-0.0-0.1-0.3-1.5-0.5-0.4
Social responses0.30.31.3-0.40.4-0.70.8-0.50.9-0.6-0.3-0.6-0.3-0.1-1.1-0.3-0.2
Social time0.20.31.0-0.10.1-0.91.0-0.70.9-0.3-0.1-0.5-0.30.20.30.1-0.0
Conditioned locomotion0.50.61.0-0.90.90.2-0.3-0.10.4-0.8-0.8-1.0-0.9-0.8-0.9-0.8-0.8
Cocaine response after cond. corrected1.11.23.00.9-0.9-1.61.5-1.71.00.90.80.50.30.81.31.20.8
Cocaine response after cond. not corrected0.70.81.70.9-0.9-1.21.1-1.30.70.80.60.90.70.61.11.00.6
Cocaine response before conditioning0.70.82.0-0.50.51.3-1.11.3-0.8-0.6-0.80.40.5-0.7-1.4-0.8-0.8
Saline control response1.82.53.9-1.81.80.1-0.1-0.71.4-1.9-1.9-1.9-1.9-1.9-0.4-2.0-1.9
Condit. Reinf. active minus inactive responses0.40.51.80.6-0.60.8-0.71.3-1.30.60.50.70.80.50.40.50.4
Condit. Reinf. active-inactive response ratio1.61.76.10.9-0.91.7-1.62.1-2.51.10.61.21.10.60.70.80.6
Condit. Reinf. active responses0.00.10.2-0.00.00.3-0.30.5-0.3-0.1-0.1-0.00.0-0.1-0.4-0.2-0.1
Condit. Reinf. inactive responses0.60.72.9-0.40.4-1.31.2-1.41.7-0.6-0.4-0.6-0.5-0.3-0.7-0.4-0.3
Condit. Reinf. lever presses0.91.23.3-1.01.01.3-1.31.0-0.5-1.0-1.1-0.6-0.6-1.1-1.8-1.3-1.1
Condit. Reinf. lever reinforcers received0.20.20.5-0.40.40.6-0.50.7-0.4-0.4-0.5-0.3-0.2-0.4-0.7-0.5-0.5
Pavlov. Cond. lever latency0.50.73.40.6-0.6-0.91.0-0.50.40.50.80.10.30.81.80.80.8
Pavlov. Cond. magazine entry latency3.94.59.0-2.42.41.6-1.40.80.3-2.4-2.6-1.7-1.6-2.6-3.0-2.4-2.6
Pavlov. Cond. change in total contacts1.62.24.8-1.31.32.2-2.11.8-1.1-1.3-1.5-0.5-0.6-1.5-1.6-1.6-1.5
Pavlov. Cond. index score2.53.37.6-1.81.82.1-2.01.4-0.6-1.7-2.0-0.9-1.0-2.0-2.8-2.0-2.0
Pavlov. Cond. latency score2.43.08.0-1.61.62.0-2.01.4-0.7-1.6-1.9-0.7-0.9-1.9-2.8-1.9-1.9
Pavlov. Cond. lever contacts0.50.74.5-0.70.70.8-0.80.7-0.3-0.7-0.8-0.1-0.1-0.8-2.1-0.8-0.8
Pavlov. Cond. magazine entry number6.07.410.93.1-3.1-2.42.3-1.40.03.13.32.22.23.33.23.23.3
Pavlov. Cond. intertrial magazine entries1.31.74.01.5-1.5-0.50.60.3-0.71.41.51.11.21.52.01.61.5
Pavlov. Cond. lever-magazine prob. diff.2.73.57.0-1.91.92.0-2.01.3-0.5-1.9-2.2-1.0-1.1-2.2-2.7-2.1-2.2
Pavlov. Cond. response bias1.52.05.3-1.51.51.3-1.30.9-0.2-1.5-1.6-0.8-0.8-1.6-2.3-1.6-1.6
Conditioned reinforcement - actives2.02.03.31.4-1.40.6-0.41.5-1.81.41.21.81.81.31.61.51.3
Conditioned reinforcement - inactives1.21.43.41.1-1.11.0-1.01.4-1.81.30.91.61.30.80.60.90.9
Conditioned locomotion1.72.03.91.8-1.80.1-0.20.4-1.42.01.32.01.61.51.21.51.4
Intermittent access intake day 1-15 change1.21.23.00.9-0.90.6-0.31.7-1.50.81.01.21.51.11.01.21.1
Intermittent access intake escalation0.80.82.30.7-0.60.6-0.31.5-1.30.60.80.91.20.80.60.90.8
Intermittent access intake escalation 20.50.53.1-0.20.21.2-0.91.7-1.2-0.2-0.10.10.4-0.1-0.30.1-0.1
Intermitt. access day 1 inactive lever presses1.51.62.81.6-1.6-0.10.20.4-1.11.71.41.71.41.31.11.51.3
Intermitt. access day 15 inactive lever presses0.60.72.50.1-0.11.5-1.61.3-1.50.3-0.30.70.1-0.1-0.5-0.3-0.3
Intermitt. access escalation Index0.60.62.20.6-0.6-1.21.0-1.50.90.60.60.40.10.60.30.50.5
Intermittent access day 1 total infusions1.11.23.61.4-1.40.5-0.8-0.1-1.31.80.71.91.00.70.70.90.7
Intermittent access day 15 total infusions3.23.67.32.2-2.20.7-0.61.3-2.32.41.72.72.31.71.61.91.7
Intermittent access terminal intake (last 3 days)1.61.75.31.0-1.01.6-1.71.7-2.31.40.51.81.20.40.30.70.5
Intermittent access total infusions1.41.53.51.3-1.31.1-1.11.0-1.91.60.71.91.30.70.61.00.7
Intermittent access day 1 locomotion0.40.41.40.8-0.80.2-0.5-0.8-0.41.20.11.00.20.10.10.40.1
Intermittent access day 15 total locomotion0.60.62.10.6-0.61.1-1.20.9-1.40.90.11.00.60.20.10.30.1
Intermittent access total locomotion1.11.34.30.7-0.81.8-2.01.2-2.11.2-0.11.40.5-0.00.10.2-0.1
Intermittent access standard deviation1.01.12.31.0-1.00.20.01.1-1.21.01.11.21.51.01.01.21.0
Cocaine induced anxiety0.50.51.6-0.50.61.0-1.01.0-0.6-0.5-0.6-0.3-0.3-0.6-1.3-0.5-0.6
Post-drug Anxiety1.01.12.4-0.90.91.4-1.41.5-0.9-0.9-0.9-0.6-0.6-0.9-1.5-0.9-0.9
Baseline Anxiety0.90.91.6-1.21.20.1-0.1-0.30.8-1.2-1.0-1.3-1.2-1.0-0.4-1.1-1.0
Lifetime Intake1.01.13.01.3-1.30.4-0.60.3-1.21.60.71.71.20.70.51.00.8
Incentive Sensitization - Responses0.50.51.7-0.10.11.3-1.31.1-1.10.1-0.60.30.0-0.3-0.1-0.3-0.4
Incentive Sensitization - Breakpoint0.50.51.80.0-0.01.3-1.31.2-1.20.2-0.40.50.2-0.2-0.0-0.2-0.3
Progressive ratio test 1 active lever presses1.51.62.61.5-1.5-0.10.20.3-1.01.61.21.61.61.11.31.51.2
Progressive ratio test 1 breakpoint1.71.82.91.6-1.6-0.20.30.4-1.11.71.31.71.71.21.41.61.3
Progressive ratio test 1 inactive lever presses0.10.10.5-0.10.1-0.20.1-0.70.40.0-0.4-0.0-0.3-0.4-0.3-0.1-0.3
Progressive ratio test 2 active lever presses1.71.83.51.5-1.50.7-0.61.1-1.81.70.91.91.61.01.31.31.1
Progressive ratio test 2 breakpoint2.42.74.71.8-1.80.4-0.31.1-1.92.01.32.22.01.51.81.81.5
Progressive ratio test 2 inactive lever presses1.01.23.31.1-1.11.1-1.11.2-1.81.30.41.61.10.50.40.80.5
Total sessions with >9 infusions1.61.83.51.7-1.7-0.70.5-0.8-0.41.91.21.81.41.31.21.51.4
Short access day 1 total inactive lever presses0.80.92.01.3-1.3-0.40.3-0.7-0.31.41.01.30.90.81.01.01.0
Short access day 10 total inactive lever presses2.32.53.21.7-1.8-1.81.8-1.60.61.71.81.41.31.81.31.71.8
Short access day 1 total infusions0.91.02.01.3-1.3-0.60.4-0.8-0.21.40.91.41.00.80.71.11.0
Short access day 10 total infusions0.50.51.90.9-0.90.3-0.6-0.3-0.71.30.41.40.50.30.40.50.3
Short access total infusions0.50.61.61.0-1.0-0.30.1-0.8-0.21.30.51.20.60.50.30.80.6
Short access day 1 locomotion0.10.10.50.2-0.20.1-0.4-0.7-0.00.5-0.30.4-0.2-0.2-0.1-0.1-0.2
Short access day 10 total locomotion0.10.10.40.2-0.20.4-0.7-0.2-0.40.5-0.10.4-0.2-0.1-0.1-0.0-0.2
Short access total locomotion0.20.20.40.0-0.00.4-0.7-0.6-0.10.3-0.50.2-0.5-0.5-0.3-0.3-0.5
Compulsive drug intake2.42.37.2-1.21.2-1.81.7-2.22.7-1.5-0.7-2.0-1.4-0.7-0.9-1.0-0.8
One hour access (0.3 mA shock)3.23.86.92.4-2.40.1-0.00.7-1.82.61.92.62.31.91.72.22.0
One hour access (shock baseline)4.85.59.72.6-2.61.1-0.92.2-3.12.82.13.12.82.01.82.52.1
Number of responses in last shaping day0.30.31.40.0-0.0-0.90.8-1.21.00.0-0.0-0.1-0.1-0.00.10.20.0
Context. condit. distance diff. score0.40.51.20.8-0.8-0.80.7-1.10.40.90.50.30.10.60.50.90.5
Locomotion velocity, session 10.40.52.20.1-0.1-1.11.0-1.51.20.0-0.2-0.3-0.5-0.1-0.10.2-0.2
Locomotion distance, session 10.50.71.6-0.60.6-0.40.2-1.21.0-0.5-0.9-0.9-1.3-0.9-0.9-0.5-0.9
Locomotion velocity, session 22.22.63.9-1.81.80.9-1.00.10.4-1.6-2.0-1.7-2.0-2.0-2.0-1.8-2.0
Locomotion distance, session 20.30.41.0-0.50.5-0.60.5-0.90.9-0.5-0.6-0.9-1.0-0.6-0.6-0.3-0.6
Locomotion velocity, session 30.20.20.6-0.20.10.0-0.4-0.70.30.1-0.5-0.3-0.8-0.5-0.5-0.5-0.5
Locomotion distance, session 30.10.10.6-0.10.1-0.60.4-0.80.8-0.1-0.1-0.2-0.3-0.1-0.1-0.3-0.1
Stereotopy head waving bouts, day 30.20.20.80.6-0.60.2-0.5-0.3-0.50.90.10.2-0.30.10.20.50.1
Stereotopy head waving duration, day 30.10.20.60.5-0.5-0.30.1-0.6-0.00.80.2-0.0-0.40.20.20.60.2
Locomotion velocity, session 70.10.10.20.3-0.30.3-0.40.1-0.50.40.00.0-0.10.10.00.30.0
Locomotion distance, session 70.20.31.20.5-0.5-0.90.6-1.10.60.60.30.1-0.20.40.30.50.3
Stereotopy head waving bouts, day 70.40.51.6-0.30.31.3-1.21.1-1.1-0.1-0.5-0.3-0.4-0.5-0.5-0.3-0.5
Stereotopy head waving duration, day 71.62.02.7-1.51.51.4-1.40.8-0.3-1.4-1.6-1.2-1.3-1.6-1.6-1.6-1.6
Locomotion velocity, session 80.50.62.10.1-0.1-1.41.4-1.41.30.0-0.0-0.6-0.50.00.00.4-0.0
Locomotion distance, session 80.20.30.80.7-0.7-0.40.1-0.6-0.10.90.40.3-0.10.40.40.80.4
Degree of sensitization distance0.10.10.50.5-0.50.2-0.5-0.2-0.40.70.20.5-0.10.30.20.40.2
Degree of sensitization stereotypy1.21.32.7-1.01.01.6-1.51.3-0.9-0.9-1.2-0.7-0.7-1.2-1.2-1.1-1.2
Condit. Reinf. active minus inactive responses0.91.01.4-1.11.10.7-0.70.30.2-1.1-1.1-1.0-1.0-1.2-1.2-1.1-1.1
Condit. Reinf. active-inactive response ratio0.40.40.9-0.80.8-0.00.0-0.10.6-0.9-0.7-1.0-0.8-0.7-0.7-0.6-0.7
Condit. Reinf. active responses1.01.22.5-1.01.01.5-1.61.1-0.7-0.8-1.2-0.6-0.8-1.2-1.2-1.1-1.2
Condit. Reinf. inactive responses0.60.72.30.2-0.21.5-1.51.3-1.50.40.00.90.6-0.00.0-0.10.0
Incentive salience index mean1.01.21.8-1.11.10.9-1.10.20.1-1.0-1.3-0.9-1.1-1.3-1.3-1.3-1.3
Condit. Reinf. lever presses0.50.61.2-0.80.80.9-1.10.1-0.1-0.6-1.0-0.3-0.7-1.0-1.0-1.1-1.0
Time in familiar zone, hab. session 10.00.00.2-0.10.10.1-0.3-0.20.1-0.1-0.20.40.2-0.2-0.2-0.3-0.2
Time in novel zone, hab. session 11.31.21.91.2-1.2-1.31.4-0.90.41.01.30.70.91.31.31.21.3
Total zone transitions, hab. session 10.30.41.0-0.60.60.1-0.1-0.10.3-0.6-0.7-1.0-1.0-0.7-0.6-0.5-0.7
Total locomotion distance, hab. session 10.10.20.70.4-0.40.6-0.70.5-0.90.60.10.2-0.20.10.10.40.1
Locomotion velocity, hab. session 10.20.30.8-0.30.30.8-0.90.6-0.6-0.1-0.5-0.5-0.7-0.5-0.5-0.2-0.5
Time in familiar zone, hab. session 20.70.82.10.5-0.5-1.41.5-1.11.20.20.80.70.90.80.70.30.8
Time in novel zone, hab. session 20.50.51.0-0.60.60.8-0.90.3-0.3-0.4-0.8-0.7-1.0-0.8-0.8-0.6-0.8
Total zone transitions, hab. session 21.01.42.2-1.21.20.0-0.2-0.81.1-1.1-1.4-1.2-1.5-1.4-1.4-1.3-1.4
Total locomotion distance, hab. session 20.10.10.3-0.20.20.0-0.2-0.50.3-0.0-0.4-0.2-0.6-0.4-0.4-0.2-0.4
Locomotion velocity, hab. session 20.00.10.20.0-0.00.3-0.5-0.1-0.20.2-0.3-0.0-0.5-0.3-0.3-0.1-0.3
Novel to familiar place preference ratio1.92.02.7-1.51.51.6-1.61.1-0.6-1.3-1.5-1.2-1.3-1.5-1.5-1.6-1.5
Novelty place preference1.21.22.1-1.21.21.4-1.41.1-0.7-1.0-1.1-0.8-0.9-1.1-1.1-1.3-1.1
Time in novel zone, NPP test1.21.21.8-1.21.21.3-1.30.9-0.5-1.0-1.2-0.9-1.0-1.1-1.2-1.3-1.2
Total zone transitions, NPP test1.01.52.5-1.31.30.0-0.1-0.61.0-1.3-1.5-1.5-1.6-1.5-1.5-1.1-1.5
Total locomotion distance, NPP test0.10.20.5-0.20.2-0.40.2-0.70.5-0.1-0.4-0.4-0.6-0.5-0.40.0-0.4
Locomotion velocity, NPP test0.10.10.3-0.10.1-0.30.3-0.50.4-0.1-0.3-0.5-0.6-0.4-0.40.1-0.3
Pavlov. Cond. lever latency0.91.22.21.0-1.0-1.31.5-0.60.40.91.30.50.91.31.31.31.3
Pavlov. Cond. magazine entry latency1.11.53.8-1.01.01.9-2.01.4-1.1-0.8-1.2-0.2-0.5-1.2-1.2-1.3-1.2
Pavlov. Cond. change in total contacts1.11.13.8-0.40.41.9-1.91.8-1.6-0.3-0.70.30.1-0.7-0.7-0.6-0.7
Pavlov. Cond. index score0.70.92.0-0.80.81.4-1.41.1-0.8-0.7-0.9-0.2-0.4-1.0-1.0-1.0-0.9
Pavlov. Cond. latency score0.50.61.3-0.70.71.1-1.20.7-0.5-0.6-0.8-0.1-0.4-0.9-0.9-0.9-0.8
Pavlov. Cond. lever contacts0.20.20.7-0.40.40.7-0.80.4-0.3-0.3-0.50.1-0.2-0.5-0.6-0.6-0.5
Pavlov. Cond. magazine entry number1.01.22.80.9-1.0-1.71.5-1.51.00.91.10.30.31.11.11.01.1
Pavlov. Cond. intertrial magazine entries0.20.21.2-0.30.30.8-0.51.1-0.7-0.4-0.3-0.20.1-0.3-0.3-0.1-0.3
Pavlov. Cond. lever-magazine prob. diff.0.91.12.6-0.90.91.6-1.61.3-0.9-0.8-1.0-0.3-0.5-1.1-1.1-1.1-1.0
Pavlov. Cond. response bias0.91.12.6-0.90.91.6-1.61.3-0.9-0.8-1.0-0.1-0.3-1.0-1.0-1.0-1.0
Bone: apparent density0.20.31.1-0.40.40.8-1.00.3-0.4-0.3-0.5-0.2-0.6-0.5-0.6-0.5-0.5
Bone surface1.62.86.3-1.61.62.3-2.51.5-1.0-1.3-1.7-1.0-1.4-1.7-1.8-1.8-1.7
Bone volume0.91.55.0-0.90.92.1-2.21.5-1.3-0.6-1.0-0.4-0.7-1.0-1.1-1.1-1.0
Bone: connectivity density1.11.72.6-1.41.41.2-1.40.20.0-1.2-1.5-1.0-1.4-1.5-1.6-1.6-1.5
Bone: cortical apparent density0.50.71.6-1.01.00.10.10.00.5-1.1-0.8-1.3-1.0-0.9-0.9-0.7-0.8
Bone: cortical area0.81.32.3-1.01.01.4-1.51.1-0.6-0.9-1.3-0.7-0.8-1.2-1.2-1.3-1.3
Bone: cortical porosity0.00.00.1-0.00.0-0.00.20.4-0.2-0.10.0-0.4-0.10.10.10.30.0
Bone: cortical porosity0.10.10.6-0.40.4-0.20.30.10.3-0.4-0.3-0.7-0.4-0.2-0.2-0.0-0.3
Bone: cortical thickness2.74.57.1-2.52.50.10.0-0.41.7-2.6-2.4-2.7-2.3-2.4-2.3-2.4-2.4
Bone: cortical thickness0.70.82.1-0.90.9-0.80.8-1.01.4-1.0-0.8-1.1-0.9-0.8-0.8-0.7-0.8
Bone: cortical tissue density0.70.82.0-1.11.10.10.10.00.6-1.2-0.9-1.4-1.1-1.0-1.0-0.8-0.9
Bone: elastic displacement0.70.82.80.6-0.6-1.51.7-1.11.00.40.80.20.40.80.80.80.8
Bone: elastic work1.01.22.8-1.11.0-0.90.8-1.31.7-1.2-1.0-1.4-1.3-1.0-0.9-0.9-1.0
Bone: endosteal estimation1.43.16.02.0-2.00.9-1.30.8-2.22.41.62.51.71.61.61.61.6
Bone: endosteal perimeter2.55.110.62.4-2.41.7-2.01.9-3.32.81.92.92.21.91.91.81.9
Bone: final force1.62.53.6-1.61.61.6-1.70.7-0.2-1.5-1.9-1.3-1.6-1.9-1.9-1.9-1.9
Bone: final moment1.52.43.5-1.61.61.5-1.70.7-0.2-1.5-1.8-1.3-1.6-1.8-1.8-1.9-1.8
Bone: marrow area1.63.46.42.1-2.20.8-1.20.8-2.22.51.72.51.81.81.71.71.7
Bone: maximum diameter0.51.03.8-0.20.21.8-1.91.6-1.60.0-0.60.1-0.2-0.6-0.5-0.5-0.6
Bone: maximum force2.13.77.9-1.71.72.5-2.81.3-0.9-1.4-2.1-1.1-1.7-2.1-2.1-2.2-2.1
Bone: maximum moment1.93.47.0-1.71.72.3-2.71.2-0.8-1.4-2.0-1.1-1.6-2.0-2.0-2.2-2.0
Bone: minimum diameter1.01.94.21.4-1.41.2-1.61.1-2.11.81.01.91.21.01.10.91.0
Bone: periosteal estimation0.61.24.30.5-0.51.8-2.11.5-2.00.90.11.00.40.10.10.10.1
Bone: periosteal perimeter0.60.93.30.3-0.31.7-1.81.6-1.80.6-0.00.70.40.00.1-0.0-0.0
Bone: post-yield work1.82.47.90.9-0.92.4-2.72.0-2.81.30.41.71.00.50.40.50.4
Bone: stiffness1.01.54.4-0.90.92.0-2.11.6-1.2-0.7-1.1-0.4-0.7-1.1-1.1-1.3-1.1
Bone: tissue strength0.30.30.70.5-0.5-0.40.4-0.30.10.40.70.80.80.70.60.20.7
Bone: trabecular number0.50.82.1-0.80.81.2-1.40.6-0.5-0.6-0.9-0.5-0.9-0.9-1.0-1.0-0.9
Bone: trabecular spacing0.60.72.70.5-0.5-1.51.6-1.21.20.20.50.40.70.60.60.50.5
Bone: trabecular thickness0.50.61.80.6-0.60.9-0.81.1-1.30.60.60.80.70.60.60.60.6
Bone: trabecular tissue density3.14.37.42.4-2.4-1.61.8-0.4-0.42.22.41.92.12.42.42.72.4
Breakpoint value in progressive ratio session2.02.33.3-1.81.81.2-1.11.2-0.1-1.8-1.7-1.7-1.3-1.6-1.6-1.6-1.6
Distance traveled before self-admin2.22.43.0-1.61.61.7-1.71.3-0.5-1.6-1.6-1.4-1.4-1.6-1.7-1.7-1.6
Distance traveled after self-admin0.30.40.8-0.60.60.8-0.80.9-0.4-0.7-0.6-0.5-0.3-0.3-0.4-0.7-0.4
Delta time in closed arm before/after self-admin2.12.15.5-1.11.1-1.41.1-2.32.4-1.1-1.2-1.6-1.8-1.0-1.0-1.0-1.0
Delta time in open arm before/after self-admin2.32.14.2-1.31.32.0-1.91.9-1.1-1.3-1.5-0.9-0.9-1.5-1.5-1.3-1.5
Diff in mean of infusions in LGA sessions1.71.93.4-1.71.70.4-0.30.40.7-1.8-1.5-1.8-1.5-1.5-1.5-1.4-1.5
Extinction: sum of active levers before priming3.33.34.5-2.12.11.4-1.50.90.1-2.1-2.1-2.0-2.0-2.0-2.0-2.1-2.0
Active lever presses in extinction session 62.92.83.5-1.91.91.8-1.61.6-0.5-1.9-1.8-1.5-1.3-1.8-1.9-1.8-1.8
Delta distance traveled before/after self-admin0.80.81.50.8-0.8-1.21.1-0.90.70.70.90.60.71.11.00.81.0
Delta ambulatory time before/after self-admin1.21.32.61.0-1.0-1.61.5-1.20.80.81.20.70.81.31.21.01.3
Time in closed arm before self-admin0.40.51.80.2-0.21.2-1.11.3-1.30.2-0.10.60.50.10.1-0.00.1
Time in closed arm after self-admin0.70.71.20.8-0.9-1.10.9-1.00.50.80.60.70.60.90.90.80.9
Time in open arm before self-admin2.42.67.90.9-0.9-2.82.7-2.82.20.81.30.20.21.11.11.11.2
Time in open arm after self-admin0.20.20.6-0.40.4-0.50.6-0.30.6-0.5-0.0-0.8-0.4-0.3-0.3-0.1-0.2
Sum of active levers in priming session hrs 5-62.32.27.0-1.31.32.3-1.92.6-1.5-1.4-1.2-0.9-0.5-1.2-1.2-1.2-1.2
Time to tail flick, vehicle, before self-admin0.60.61.9-0.40.41.2-1.40.6-0.7-0.2-0.8-0.1-0.7-0.8-0.8-0.7-0.7
Time to tail flick, vehicle, after self-admin0.40.41.0-0.50.5-0.40.2-1.00.9-0.4-0.7-0.6-0.9-0.6-0.5-0.6-0.5
Time to tail flick, test, before self-admin0.30.31.4-0.20.1-0.3-0.1-1.20.70.1-0.2-0.5-0.9-0.3-0.2-0.4-0.3
Time to tail flick, test, after self-admin0.10.10.20.3-0.3-0.20.20.0-0.10.20.40.10.20.30.40.30.3
Delta time to tail flick, vehicle, before/after SA0.20.20.8-0.10.1-0.80.8-0.90.9-0.1-0.0-0.3-0.20.0-0.00.00.0
Delta time to tail flick, test, before/after SA0.10.11.1-0.20.20.30.01.1-0.5-0.4-0.0-0.10.40.0-0.00.10.0
Ambulatory time before self-admin2.42.64.6-1.51.52.1-2.01.9-1.0-1.5-1.6-1.0-1.0-1.6-1.7-1.6-1.6
Ambulatory time after self-admin0.50.51.6-0.40.41.3-1.31.3-0.9-0.4-0.60.0-0.0-0.3-0.4-0.6-0.4
Total heroin consumption3.44.17.0-2.52.50.9-0.70.70.8-2.6-2.2-2.7-2.2-2.2-2.3-2.2-2.2
Area under the delay curve0.10.10.50.1-0.1-0.40.2-0.70.40.2-0.10.0-0.30.00.10.0-0.1
Delay disc. indifference point, 0s delay0.50.51.90.7-0.7-1.00.7-1.40.60.90.50.60.10.50.70.70.5
Delay disc. indifference point, 16s delay0.10.10.6-0.10.10.7-0.80.4-0.50.0-0.30.1-0.2-0.2-0.0-0.3-0.3
Delay disc. indifference point, 2s delay0.20.30.90.7-0.70.1-0.2-0.1-0.40.80.40.90.40.50.50.50.4
Delay disc. indifference point, 24s delay0.30.31.1-0.30.2-0.80.6-1.11.0-0.3-0.2-0.5-0.5-0.2-0.1-0.3-0.2
Delay disc. indifference point, 4s delay0.50.62.2-0.40.4-0.90.6-1.51.3-0.3-0.4-0.6-1.0-0.5-0.3-0.3-0.4
Delay disc. indifference point, 8s delay0.60.61.70.6-0.6-1.31.2-1.30.90.60.60.10.10.70.60.70.6
Delay discount exponential model param0.10.10.5-0.10.10.4-0.20.7-0.4-0.20.1-0.00.3-0.0-0.1-0.00.1
Delay discount hyperbolic model param0.10.10.5-0.10.10.4-0.20.7-0.4-0.20.1-0.00.30.0-0.0-0.00.1
Fecal boli incidents, locomotor time 10.91.03.40.5-0.51.4-1.21.8-1.90.50.40.90.90.40.80.40.4
Change in fecal boli incidents, locomotor task1.41.34.00.9-0.9-1.91.7-2.01.30.91.00.50.10.90.51.00.9
Time >=10cm from walls, locomotor time 12.72.75.51.7-1.71.1-1.01.5-2.31.91.42.01.81.51.81.41.4
Bouts of movement, locomotor time 10.30.41.1-0.80.80.30.20.90.0-1.0-0.6-0.9-0.1-0.6-0.3-0.5-0.6
Total resting periods, locomotor time 10.40.41.2-0.70.70.6-0.21.1-0.3-0.9-0.6-0.7-0.1-0.6-0.3-0.5-0.6
Rest time, locomotor task time 11.01.12.01.1-1.1-0.60.80.0-0.31.01.30.91.11.41.31.41.4
Distance moved, locomotor task time 10.20.20.5-0.40.40.3-0.4-0.10.1-0.3-0.6-0.0-0.4-0.6-0.7-0.6-0.6
Vertical activity count, locomotor time 10.50.50.90.9-0.9-0.50.5-0.3-0.10.90.91.00.80.80.60.80.8
Time >=10cm from walls, locomotor time 20.40.52.10.2-0.21.0-0.81.4-1.30.20.20.40.70.20.50.20.3
Bouts of movement, locomotor time 21.11.22.0-1.31.30.5-0.40.20.5-1.4-1.4-1.2-1.1-1.3-1.2-1.2-1.3
Total resting periods, locomotor time 20.50.61.0-0.90.90.4-0.40.20.2-1.0-1.0-0.8-0.7-0.8-0.9-0.8-0.9
Rest time, locomotor task time 22.73.25.22.1-2.1-1.01.0-0.3-0.62.02.11.71.82.32.02.12.2
Distance moved, locomotor task time 20.50.61.1-0.90.90.3-0.10.30.3-1.1-1.0-0.7-0.5-1.0-1.0-0.8-0.9
Vertical activity count, locomotor time 20.40.52.0-0.20.2-1.31.4-1.01.3-0.40.2-0.5-0.10.1-0.00.10.1
Weight adjusted by age1.41.62.4-1.31.31.5-1.51.0-0.4-1.2-1.3-0.9-0.9-1.4-1.3-1.5-1.5
Seeking ratio, delayed vs. immediate footshock0.00.00.2-0.00.0-0.20.2-0.40.2-0.0-0.0-0.0-0.20.0-0.50.00.0
Locomotion in novel chamber2.32.95.61.8-1.80.9-0.81.4-2.21.91.52.42.11.51.71.51.5
Locomotion in novel chamber post-restriction1.82.24.11.8-1.8-0.60.60.4-0.91.81.61.31.41.72.01.91.7
Progressive ratio0.20.20.80.1-0.10.8-0.90.7-0.70.2-0.00.40.20.00.3-0.30.0
Food seeking constrained by brief footshock0.30.31.10.3-0.3-1.01.0-1.00.80.20.30.1-0.00.50.50.40.3
Seeking ratio, punishment vs. effort0.60.82.80.1-0.1-1.61.6-1.71.50.00.2-0.3-0.30.20.10.50.2
Run reversals in cocaine runway, females1.01.04.1-0.60.6-0.90.5-2.01.6-0.5-0.7-0.9-1.3-0.8-0.8-0.8-0.7
Run reversals in cocaine runway, males0.40.40.70.7-0.7-0.70.8-0.30.10.60.80.40.50.80.60.80.8
Latency to leave start box in cocaine runway0.40.41.20.8-0.80.1-0.40.1-0.61.00.51.10.60.60.60.60.5
Latency to leave start box in cocaine runway, F0.00.10.2-0.0-0.00.3-0.50.3-0.30.1-0.20.2-0.0-0.1-0.1-0.1-0.2
Latency to leave start box in cocaine runway, M2.82.74.12.0-2.0-0.80.5-0.1-0.62.01.92.01.81.82.01.91.9
Cd content in liver1.21.34.81.2-1.2-0.00.10.5-0.91.20.91.21.21.12.21.41.0
Co content in liver2.32.78.01.2-1.2-2.62.8-1.91.70.91.50.61.11.51.31.61.5
Cu content in liver0.40.51.5-0.60.6-0.80.7-1.01.2-0.6-0.4-0.9-0.8-0.4-0.5-0.4-0.4
Fe content in liver0.10.10.30.0-0.00.5-0.50.5-0.60.1-0.10.10.1-0.1-0.20.1-0.1
K content in liver1.11.14.1-0.80.81.2-1.40.6-0.5-0.6-1.0-0.7-0.9-1.0-2.0-1.2-1.0
Mg content in liver0.40.41.8-0.30.30.8-1.10.2-0.4-0.1-0.5-0.3-0.7-0.5-1.3-0.7-0.5
Mn content in liver2.22.58.5-1.61.61.4-1.50.9-0.2-1.5-1.5-1.3-1.3-1.5-2.9-1.8-1.5
Na content in liver0.80.81.7-0.80.81.3-1.31.0-0.7-0.6-0.8-0.6-0.6-0.9-1.1-0.9-0.9
Rb content in liver1.51.92.91.6-1.6-1.31.1-1.10.31.61.51.41.11.51.71.41.5
Se content in liver1.11.33.9-0.40.42.0-2.01.9-1.7-0.2-0.6-0.0-0.1-0.5-1.6-0.6-0.5
Sr content in liver5.04.66.6-2.52.51.5-1.40.90.3-2.5-2.6-2.4-2.3-2.5-2.0-2.4-2.5
Zn content in liver3.74.15.8-2.22.21.8-1.91.1-0.2-2.1-2.4-2.2-2.3-2.4-2.0-2.2-2.4