Osbp2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000019645 0.08 0.04 1.6e-06 0.06 0.04 0.05 0.05 4.5e-07 7.9e-06 5.5e-06 1.2e-06
2 Brain intron excision ratio chr14:78595943:78596214 0.08 0.04 2.4e-07 0.04 0.06 0.06 0.06 6.8e-05 2.4e-06 2.9e-06 6.7e-06
3 Brain mRNA stability ENSRNOG00000019645 0.07 0.04 1.6e-04 0.01 0.04 0.03 0.03 4.3e-02 3.4e-04 2.2e-03 1.1e-03
4 IL mRNA stability ENSRNOG00000019645 0.22 0.11 2.4e-03 0.13 0.07 0.07 0.06 5.9e-04 8.3e-03 8.0e-03 1.7e-02
5 LHb isoform ratio ENSRNOT00000065501 0.21 0.11 6.0e-03 -0.01 0.07 0.08 0.01 6.5e-01 1.1e-02 7.3e-03 1.4e-01
6 NAcc mRNA stability ENSRNOG00000019645 0.09 0.05 4.3e-04 0.04 0.05 0.05 0.05 5.7e-04 7.1e-05 1.1e-04 7.4e-05
7 OFC gene expression ENSRNOG00000019645 0.28 0.12 8.8e-05 0.17 0.13 0.15 0.15 7.3e-05 4.5e-04 2.1e-04 2.3e-04
8 OFC mRNA stability ENSRNOG00000019645 0.32 0.13 7.8e-05 0.18 0.1 0.17 0.19 4.8e-05 2.2e-03 8.4e-05 3.2e-05
9 PL mRNA stability ENSRNOG00000019645 0.22 0.09 3.3e-09 0.07 0.09 0.07 0.08 5.8e-06 1.5e-07 6.7e-06 6.2e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail2.16.913.03.2-0.81.83.02.13.6-0.63.03.6
BMI without tail1.22.67.52.7-0.10.71.41.42.0-1.21.42.0
Body weight0.83.611.73.4-1.8-0.11.61.02.3-1.81.51.9
Epididymis fat weight0.71.74.81.1-0.91.11.52.21.30.21.41.3
Glucose3.35.128.0-0.7-1.6-2.8-1.3-5.3-0.9-0.4-1.4-1.5
Heart weight0.10.10.80.10.90.0-0.30.1-0.1-0.3-0.20.1
Left kidney weight0.20.62.11.10.80.0-0.01.4-0.1-1.0-0.10.1
Right kidney weight0.82.110.60.5-0.31.61.33.31.00.41.41.1
Tail length0.82.34.71.1-0.4-2.2-1.7-1.0-1.3-2.0-1.7-1.6
Length with tail0.72.65.61.6-0.8-2.3-1.6-0.9-1.1-2.4-1.5-1.4
Length without tail0.20.51.30.8-0.8-1.1-0.5-0.7-0.2-1.0-0.5-0.4
Liver weight, left0.71.14.0-1.50.60.9-0.12.0-0.71.2-0.1-0.6
Liver weight, right1.21.96.30.81.91.70.82.50.9-0.10.91.4
Parametrial fat weight0.40.71.3-0.8-1.00.30.8-1.20.61.10.80.5
Retroperitoneal fat weight0.51.73.40.4-0.21.61.60.81.70.81.61.8
Intraocular pressure0.40.51.60.81.2-0.1-0.0-1.30.4-0.8-0.00.6
Extensor digitorum longus weight0.73.010.43.2-1.4-2.0-0.3-1.50.7-2.8-0.30.2
Soleus weight1.33.811.52.70.4-2.5-1.7-1.0-0.9-3.4-1.7-1.1
Tibialis anterior weight0.41.44.02.0-0.9-1.5-0.5-1.20.2-1.9-0.5-0.1
Tibia length0.30.83.01.40.00.40.41.70.5-0.80.40.6
Number of licking bursts0.60.71.51.1-0.7-1.0-0.6-0.3-0.5-1.2-0.6-0.6
Food consumed during 24 hour testing period2.53.06.20.31.2-2.1-1.9-2.5-1.6-1.5-1.9-1.6
Times rat made contact with spout2.12.45.7-1.60.9-1.4-1.5-2.4-1.80.1-1.5-1.8
Mean time between licks in bursts2.23.05.4-1.21.2-1.5-2.0-2.3-2.1-0.2-2.0-2.0
Mean num. licks in bursts0.91.14.5-2.11.20.1-0.4-1.1-0.71.2-0.4-0.5
Std. dev. time between licks in bursts0.40.50.8-0.60.9-0.1-0.7-0.8-0.90.4-0.7-0.8
Water consumed over 24 hours3.54.16.7-0.91.4-2.0-2.4-2.6-2.5-0.8-2.3-2.4
Indifference point 0 sec0.10.10.40.6-0.0-0.20.0-0.4-0.0-0.6-0.00.0
Indifference point AUC0.80.93.0-1.00.8-0.7-0.7-1.7-0.90.3-0.9-0.9
Indifference point function ln k0.20.20.5-0.2-0.4-0.5-0.50.7-0.6-0.2-0.4-0.7
Indifference point function log k0.20.20.5-0.2-0.4-0.5-0.50.7-0.6-0.2-0.4-0.7
Delay discounting total patch changes 0 sec0.10.20.60.80.1-0.4-0.1-0.7-0.0-0.8-0.2-0.0
Delay discounting total patch changes 12 sec0.10.20.60.8-0.10.10.5-0.00.5-0.30.30.4
Delay discounting total patch changes 18 sec0.20.32.20.40.3-0.4-0.1-1.50.1-0.4-0.20.1
Delay discounting total patch changes 24 sec0.81.02.60.11.61.50.90.40.90.50.71.3
Delay discounting total patch changes 6 sec0.40.61.80.10.3-1.0-0.6-1.3-0.6-0.6-0.7-0.7
Delay discounting time to switch 0 sec2.43.78.31.4-0.42.22.12.92.00.32.12.3
Delay discounting water rate 0 sec3.96.311.01.21.4-3.3-2.8-3.3-1.8-2.9-2.8-2.0
Delay discounting water rate 12 sec1.62.44.31.01.6-1.8-1.7-1.8-0.9-2.1-1.7-0.9
Delay discounting water rate 18 sec1.31.84.81.51.5-1.1-1.40.1-0.8-2.2-1.4-0.6
Delay discounting water rate 24 sec4.76.413.82.12.7-2.8-2.8-2.1-1.6-3.7-2.8-1.4
Delay discounting water rate 6 sec3.04.39.91.91.9-2.4-2.2-1.8-1.2-3.1-2.3-1.2
Locomotor activity2.13.47.4-0.40.5-2.2-2.0-2.7-1.9-1.1-2.1-2.0
Locomotor testing distance0.40.61.61.1-0.1-1.1-0.6-0.8-0.3-1.3-0.6-0.5
Locomotor testing rearing0.81.22.90.7-0.6-1.7-1.0-1.7-0.6-1.2-1.0-0.9
Light reinforcement 10.61.14.92.20.4-0.4-0.1-0.00.8-1.8-0.10.8
Light reinforcement 20.91.24.62.11.0-0.6-0.6-0.10.2-2.1-0.50.3
Reaction time number correct3.75.28.30.22.0-2.6-2.9-2.4-2.3-2.1-2.8-2.2
Reaction time mean minus median0.20.20.7-0.8-0.4-0.2-0.10.1-0.60.6-0.2-0.6
Reaction time mean minus median AUC0.10.10.40.6-0.4-0.00.40.50.4-0.20.30.3
Reaction time num false alarms2.12.94.81.2-1.31.62.21.42.20.62.22.1
Reaction time num false alarms AUC2.43.45.31.7-1.21.62.31.72.30.32.22.2
Reaction time trials correct on left3.75.28.30.22.0-2.6-2.9-2.4-2.3-2.1-2.8-2.2
Reaction time trials on left3.65.28.30.12.0-2.6-2.9-2.4-2.3-2.0-2.8-2.2
Reaction time mean0.50.61.6-0.9-0.90.80.71.00.11.20.60.2
Reaction time mean AUC0.40.61.4-0.8-0.80.80.61.20.11.10.50.2
Median of all reaction times0.70.91.9-0.9-0.91.10.91.30.31.40.80.4
Reaction time omissions0.20.30.7-0.7-0.10.50.30.80.20.80.40.2
Reaction time false alarm rate5.27.411.71.6-2.12.73.42.93.21.13.33.1
Reaction time premature initiation rate0.60.82.70.11.71.30.51.30.50.30.40.8
Reaction time premature initiations0.81.15.70.12.4-0.3-1.1-0.3-0.7-0.8-1.1-0.4
Std. dev. reaction times0.10.10.4-0.3-0.50.40.50.40.10.60.30.2
Reaction time trials completed3.65.28.30.12.0-2.6-2.9-2.4-2.3-2.0-2.8-2.2
Reaction time trials AUC3.85.48.50.11.9-2.7-2.9-2.4-2.4-2.1-2.8-2.3
Social response proportion1.61.74.3-0.30.9-1.3-1.6-2.1-1.3-0.9-1.5-1.2
Social responses1.72.15.00.00.8-1.8-1.6-2.2-1.4-1.2-1.7-1.4
Social time0.40.51.1-1.00.6-0.3-0.7-0.3-1.00.2-0.7-0.8
Conditioned locomotion2.12.54.2-0.4-0.82.11.91.81.51.61.81.6
Cocaine response after cond. corrected0.30.32.10.1-1.40.10.3-0.00.20.70.3-0.1
Cocaine response after cond. not corrected0.30.42.80.6-1.7-0.40.20.10.20.00.1-0.2
Cocaine response before conditioning0.40.41.40.70.3-1.0-0.60.0-0.3-1.2-0.6-0.4
Saline control response0.20.31.6-0.81.30.1-0.3-0.6-0.10.3-0.30.0
Condit. Reinf. active minus inactive responses0.60.82.30.61.5-0.7-1.0-0.6-0.5-1.2-0.9-0.4
Condit. Reinf. active-inactive response ratio0.20.20.4-0.2-0.30.60.6-0.00.60.50.60.6
Condit. Reinf. active responses0.50.73.4-0.21.9-0.4-0.9-0.5-0.6-0.5-0.8-0.4
Condit. Reinf. inactive responses0.70.94.3-0.42.1-0.4-1.0-0.2-0.9-0.5-0.9-0.6
Condit. Reinf. lever presses0.20.31.30.61.10.10.10.10.4-0.50.20.5
Condit. Reinf. lever reinforcers received0.20.32.50.11.60.0-0.4-0.2-0.1-0.2-0.30.0
Pavlov. Cond. lever latency0.30.42.40.9-1.6-0.10.30.30.4-0.50.20.2
Pavlov. Cond. magazine entry latency0.20.21.21.10.2-0.00.20.10.4-0.50.20.4
Pavlov. Cond. change in total contacts0.10.21.5-0.01.20.30.0-0.20.10.00.10.3
Pavlov. Cond. index score0.10.21.5-0.11.20.2-0.0-0.00.0-0.00.00.2
Pavlov. Cond. latency score0.10.21.5-0.11.20.1-0.1-0.0-0.1-0.1-0.00.1
Pavlov. Cond. lever contacts0.40.62.4-1.31.60.3-0.1-0.2-0.40.8-0.1-0.1
Pavlov. Cond. magazine entry number0.20.20.7-0.8-0.60.40.20.30.00.80.2-0.1
Pavlov. Cond. intertrial magazine entries0.10.10.7-0.8-0.2-0.1-0.10.0-0.30.5-0.0-0.3
Pavlov. Cond. lever-magazine prob. diff.0.10.21.5-0.11.20.2-0.10.0-0.1-0.1-0.00.1
Pavlov. Cond. response bias0.20.21.3-0.61.10.20.0-0.2-0.20.40.10.0
Conditioned reinforcement - actives1.11.11.90.8-1.20.71.30.61.40.41.31.3
Conditioned reinforcement - inactives0.30.41.90.5-1.4-0.30.5-0.20.7-0.10.50.4
Conditioned locomotion0.10.10.40.3-0.6-0.6-0.2-0.1-0.0-0.6-0.2-0.2
Intermittent access intake day 1-15 change0.10.10.40.3-0.6-0.10.1-0.50.30.20.20.1
Intermittent access intake escalation0.10.10.30.4-0.6-0.10.2-0.30.10.20.20.0
Intermittent access intake escalation 20.70.70.90.70.6-0.9-1.0-1.0-0.9-0.8-1.0-0.8
Intermitt. access day 1 inactive lever presses0.20.20.4-0.60.7-0.5-0.60.0-0.3-0.3-0.6-0.4
Intermitt. access day 15 inactive lever presses1.11.32.91.51.0-1.2-0.8-1.60.1-1.7-0.80.1
Intermitt. access escalation Index0.30.30.80.50.60.60.50.10.7-0.10.50.9
Intermittent access day 1 total infusions1.11.22.00.6-0.81.11.40.81.40.21.41.4
Intermittent access day 15 total infusions1.01.11.91.2-1.00.71.30.21.40.11.31.3
Intermittent access terminal intake (last 3 days)0.20.20.60.8-0.30.20.5-0.10.6-0.20.50.6
Intermittent access total infusions0.10.20.60.5-0.70.10.4-0.00.4-0.00.40.3
Intermittent access day 1 locomotion0.30.30.9-0.90.61.00.40.30.20.70.40.4
Intermittent access day 15 total locomotion1.71.83.71.1-1.20.81.70.71.9-0.31.71.8
Intermittent access total locomotion0.30.30.7-0.3-0.80.40.7-0.20.70.40.70.6
Intermittent access standard deviation0.40.41.60.81.3-0.1-0.4-0.1-0.1-0.8-0.40.1
Cocaine induced anxiety2.02.36.0-0.50.3-2.0-1.6-2.4-1.3-1.2-1.6-1.5
Post-drug Anxiety0.60.71.7-0.7-0.2-1.1-0.8-1.3-0.7-0.4-0.8-0.9
Baseline Anxiety1.61.72.60.1-1.31.41.61.51.31.01.61.3
Lifetime Intake0.10.10.70.2-0.90.00.30.00.30.10.30.1
Incentive Sensitization - Responses0.50.50.90.2-0.60.81.00.10.90.31.00.9
Incentive Sensitization - Breakpoint0.50.50.90.5-0.50.70.90.20.90.10.91.0
Progressive ratio test 1 active lever presses0.70.72.7-0.9-1.70.20.7-0.20.51.00.70.2
Progressive ratio test 1 breakpoint0.90.92.7-0.9-1.60.60.80.40.81.21.00.5
Progressive ratio test 1 inactive lever presses0.50.51.60.5-1.3-1.0-0.2-1.10.1-0.7-0.2-0.3
Progressive ratio test 2 active lever presses0.50.51.4-0.1-1.20.60.9-0.00.70.60.90.6
Progressive ratio test 2 breakpoint0.30.40.9-0.3-0.90.50.7-0.30.60.50.70.5
Progressive ratio test 2 inactive lever presses1.31.44.82.2-0.50.00.9-0.51.6-1.20.91.5
Total sessions with >9 infusions0.00.00.1-0.20.2-0.1-0.10.20.0-0.3-0.10.0
Short access day 1 total inactive lever presses1.31.43.00.9-0.2-1.7-1.0-1.6-0.7-1.6-1.1-1.0
Short access day 10 total inactive lever presses0.91.01.7-0.31.1-1.1-1.3-0.7-0.9-1.0-1.3-1.0
Short access day 1 total infusions0.20.20.60.3-0.60.30.40.80.40.10.50.3
Short access day 10 total infusions0.00.00.2-0.40.2-0.0-0.20.0-0.2-0.1-0.2-0.2
Short access total infusions0.00.00.10.1-0.2-0.1-0.30.3-0.1-0.3-0.1-0.1
Short access day 1 locomotion0.70.81.5-0.11.2-0.6-1.20.3-0.8-1.1-1.0-0.7
Short access day 10 total locomotion1.21.33.4-1.81.0-0.1-1.0-0.7-1.40.9-1.0-1.3
Short access total locomotion1.31.44.1-1.02.0-0.3-1.6-0.2-1.3-0.3-1.3-1.1
Compulsive drug intake1.11.13.0-1.60.61.10.31.5-0.51.70.1-0.3
One hour access (0.3 mA shock)0.20.21.2-0.3-1.10.20.4-0.10.10.80.4-0.1
One hour access (shock baseline)0.50.63.00.5-1.7-0.70.1-1.10.10.00.1-0.3
Number of responses in last shaping day0.91.01.90.1-0.11.41.21.01.10.71.21.1
Context. condit. distance diff. score0.40.51.60.11.11.00.21.30.20.70.40.5
Locomotion velocity, session 10.50.52.0-0.70.7-0.3-0.6-1.4-0.60.5-0.6-0.5
Locomotion distance, session 10.30.41.4-1.20.60.70.10.5-0.00.90.10.1
Locomotion velocity, session 23.23.86.9-2.10.3-1.4-1.9-2.3-2.61.2-1.9-2.6
Locomotion distance, session 20.81.14.0-1.80.91.20.4-0.2-0.22.00.30.1
Locomotion velocity, session 30.40.51.0-0.30.41.00.61.00.50.90.60.6
Locomotion distance, session 30.20.20.50.2-0.30.30.5-0.60.70.40.40.6
Stereotopy head waving bouts, day 30.30.41.10.01.0-0.1-0.7-0.1-0.80.2-0.7-0.7
Stereotopy head waving duration, day 30.30.32.20.11.50.6-0.20.4-0.20.3-0.20.1
Locomotion velocity, session 70.30.31.40.70.3-0.6-0.4-1.2-0.4-0.1-0.4-0.4
Locomotion distance, session 70.40.51.9-0.40.21.00.60.20.31.40.70.4
Stereotopy head waving bouts, day 70.91.01.40.8-0.51.11.11.11.10.51.21.1
Stereotopy head waving duration, day 71.01.22.51.6-0.40.91.11.01.4-0.31.21.4
Locomotion velocity, session 81.31.63.4-1.91.3-0.3-1.2-0.9-1.70.9-1.2-1.4
Locomotion distance, session 80.91.35.6-1.02.41.4-0.21.1-0.61.4-0.10.0
Degree of sensitization distance0.70.82.4-0.81.60.2-0.80.5-1.20.5-0.7-0.8
Degree of sensitization stereotypy0.91.02.01.4-0.70.71.00.91.2-0.31.11.1
Condit. Reinf. active minus inactive responses0.20.20.7-0.60.00.30.4-0.80.40.70.30.4
Condit. Reinf. active-inactive response ratio0.40.51.6-1.00.80.3-0.0-1.3-0.11.0-0.10.1
Condit. Reinf. active responses0.10.10.3-0.20.40.30.2-0.60.40.20.20.4
Condit. Reinf. inactive responses0.20.31.40.90.1-0.5-0.20.30.1-1.2-0.20.1
Incentive salience index mean0.20.20.7-0.2-0.2-0.00.4-0.90.60.10.30.5
Condit. Reinf. lever presses0.20.30.80.6-0.2-0.10.4-0.20.9-0.80.50.8
Time in familiar zone, hab. session 10.20.20.90.40.90.6-0.00.2-0.10.3-0.00.1
Time in novel zone, hab. session 10.60.61.6-0.4-0.6-1.2-0.7-0.4-0.6-0.9-0.7-0.8
Total zone transitions, hab. session 10.20.30.8-0.80.90.2-0.3-0.8-0.40.5-0.4-0.2
Total locomotion distance, hab. session 10.30.52.2-1.5-0.1-0.1-0.3-0.8-0.50.9-0.4-0.6
Locomotion velocity, hab. session 10.20.31.1-1.00.20.2-0.0-0.6-0.10.9-0.1-0.1
Time in familiar zone, hab. session 21.21.23.0-1.20.81.60.71.70.21.50.60.5
Time in novel zone, hab. session 22.62.67.12.00.2-2.2-1.2-2.1-0.4-2.7-1.2-0.7
Total zone transitions, hab. session 20.30.42.1-0.10.6-0.5-0.4-1.5-0.0-0.5-0.4-0.0
Total locomotion distance, hab. session 20.60.83.30.00.6-1.0-0.8-1.8-0.4-0.9-0.8-0.4
Locomotion velocity, hab. session 20.40.52.8-0.10.1-0.8-0.6-1.7-0.2-0.6-0.6-0.3
Novel to familiar place preference ratio0.50.61.4-0.7-0.90.10.7-1.20.80.70.70.5
Novelty place preference0.30.41.6-0.6-0.8-0.20.4-1.30.50.30.40.3
Time in novel zone, NPP test0.30.31.8-0.5-0.5-0.40.2-1.30.40.10.20.2
Total zone transitions, NPP test0.20.30.5-0.1-0.10.60.60.70.50.50.60.5
Total locomotion distance, NPP test0.30.40.8-0.6-0.60.60.70.40.50.90.70.4
Locomotion velocity, NPP test0.60.81.7-0.8-1.10.81.00.50.71.31.00.5
Pavlov. Cond. lever latency0.30.40.8-0.1-0.6-0.6-0.5-0.7-0.70.4-0.6-0.9
Pavlov. Cond. magazine entry latency0.40.52.2-1.51.00.1-0.5-0.1-0.50.2-0.4-0.3
Pavlov. Cond. change in total contacts0.30.31.1-0.9-0.40.10.4-1.00.40.30.40.4
Pavlov. Cond. index score0.40.52.0-1.40.90.70.20.50.20.40.40.4
Pavlov. Cond. latency score0.30.41.2-1.11.00.70.20.60.30.10.40.5
Pavlov. Cond. lever contacts0.20.20.6-0.20.80.40.20.40.4-0.30.30.6
Pavlov. Cond. magazine entry number0.50.63.31.8-1.0-0.30.30.40.4-0.50.20.2
Pavlov. Cond. intertrial magazine entries0.40.51.21.1-1.00.10.61.10.5-0.10.50.3
Pavlov. Cond. lever-magazine prob. diff.0.30.41.5-1.20.90.60.20.60.20.30.30.4
Pavlov. Cond. response bias0.10.11.1-1.00.20.20.1-0.00.00.40.20.1
Bone: apparent density0.50.94.4-2.1-0.50.2-0.30.5-0.91.1-0.3-0.9
Bone surface0.20.31.2-1.1-0.90.30.30.10.30.40.30.1
Bone volume0.20.42.6-1.6-0.80.0-0.10.0-0.30.5-0.0-0.4
Bone: connectivity density0.20.41.3-1.1-0.30.60.20.7-0.00.90.2-0.0
Bone: cortical apparent density0.50.61.0-0.8-0.30.91.00.60.90.21.01.0
Bone: cortical area1.62.49.43.1-0.3-1.4-0.1-0.51.0-2.9-0.10.8
Bone: cortical porosity0.20.20.90.8-1.0-0.2-0.00.2-0.20.3-0.0-0.4
Bone: cortical porosity0.20.21.21.1-0.40.00.10.40.00.10.1-0.0
Bone: cortical thickness1.42.39.93.1-0.5-0.60.60.31.5-2.40.61.3
Bone: cortical thickness2.22.64.81.5-0.01.81.71.72.1-0.11.72.2
Bone: cortical tissue density0.50.71.0-0.9-0.40.91.00.60.90.21.01.0
Bone: elastic displacement0.20.20.80.10.70.1-0.20.9-0.0-0.8-0.20.1
Bone: elastic work1.01.35.32.00.7-0.9-0.70.6-0.1-2.3-0.7-0.1
Bone: endosteal estimation0.30.81.11.00.4-1.1-1.0-0.7-0.8-0.9-1.0-0.8
Bone: endosteal perimeter0.30.71.80.7-0.2-1.3-0.8-1.0-0.4-1.2-0.8-0.6
Bone: final force1.01.68.73.00.8-0.30.1-0.10.8-1.90.11.0
Bone: final moment0.91.58.12.80.6-0.7-0.3-0.30.3-1.9-0.30.4
Bone: marrow area0.30.60.80.90.4-0.9-0.8-0.6-0.7-0.8-0.8-0.7
Bone: maximum diameter1.73.110.32.5-0.2-2.5-1.0-1.90.2-3.2-1.0-0.1
Bone: maximum force0.71.35.42.30.8-0.8-0.5-0.20.2-2.0-0.50.3
Bone: maximum moment0.91.64.92.20.7-1.3-1.0-0.5-0.4-2.1-1.0-0.4
Bone: minimum diameter0.40.82.21.20.7-1.1-0.9-0.2-0.5-1.5-0.9-0.5
Bone: periosteal estimation0.91.86.02.40.2-1.5-0.7-0.70.1-2.5-0.7-0.1
Bone: periosteal perimeter0.91.55.22.3-0.6-1.3-0.1-0.60.8-2.2-0.10.5
Bone: post-yield work1.01.32.9-0.7-0.3-1.3-1.3-1.0-1.6-0.1-1.3-1.7
Bone: stiffness0.50.82.41.60.30.70.80.51.1-0.10.81.1
Bone: tissue strength3.63.55.21.41.7-2.1-2.2-0.9-1.9-2.3-2.2-1.7
Bone: trabecular number0.30.41.4-1.2-0.80.3-0.00.8-0.30.80.0-0.4
Bone: trabecular spacing0.70.92.51.20.8-1.0-0.6-1.30.0-1.6-0.60.0
Bone: trabecular thickness0.81.03.7-1.9-0.50.70.11.5-0.61.10.1-0.5
Bone: trabecular tissue density0.10.10.5-0.40.10.40.40.2-0.00.70.40.1
Breakpoint value in progressive ratio session0.20.30.8-0.7-0.8-0.30.9-0.1-0.20.40.2-0.3
Distance traveled before self-admin0.91.03.6-1.9-0.6-0.2-0.6-1.0-0.91.0-0.5-1.2
Distance traveled after self-admin0.50.61.1-0.7-1.00.90.4-0.00.61.10.90.5
Delta time in closed arm before/after self-admin0.80.72.3-1.30.40.70.41.5-0.51.2-0.0-0.4
Delta time in open arm before/after self-admin0.80.71.81.3-1.1-0.60.5-1.30.7-0.70.40.5
Diff in mean of infusions in LGA sessions1.82.04.0-0.9-1.21.62.01.31.21.51.71.2
Extinction: sum of active levers before priming0.90.92.6-1.1-1.60.31.0-0.50.21.50.7-0.0
Active lever presses in extinction session 61.31.24.0-0.7-2.00.51.60.90.51.21.00.2
Delta distance traveled before/after self-admin1.71.83.40.7-0.61.51.41.21.80.51.71.8
Delta ambulatory time before/after self-admin1.31.42.4-0.4-0.71.61.11.31.21.21.51.3
Time in closed arm before self-admin0.70.82.11.31.0-0.6-1.0-0.3-0.4-1.4-0.7-0.2
Time in closed arm after self-admin0.50.51.10.01.1-0.2-0.61.0-0.9-0.3-0.7-0.7
Time in open arm before self-admin0.10.10.3-0.50.00.20.40.50.20.20.10.2
Time in open arm after self-admin0.30.30.70.5-0.20.00.6-0.80.8-0.10.50.7
Sum of active levers in priming session hrs 5-61.11.12.1-1.0-1.30.61.51.00.90.61.20.8
Time to tail flick, vehicle, before self-admin1.21.23.71.9-0.20.81.01.11.2-0.41.01.3
Time to tail flick, vehicle, after self-admin0.50.61.10.4-0.21.10.90.80.51.10.80.5
Time to tail flick, test, before self-admin0.60.61.80.71.3-0.7-0.7-0.3-0.5-0.6-1.0-0.4
Time to tail flick, test, after self-admin3.03.18.21.90.8-2.4-1.4-1.8-0.8-2.9-1.7-1.0
Delta time to tail flick, vehicle, before/after SA0.50.52.3-1.2-0.30.70.10.1-0.11.50.4-0.1
Delta time to tail flick, test, before/after SA0.90.82.20.4-0.1-1.3-0.9-1.1-0.5-1.5-0.8-0.6
Ambulatory time before self-admin0.80.82.5-1.6-0.9-0.1-0.1-0.6-0.91.3-0.3-1.1
Ambulatory time after self-admin1.11.24.3-1.6-1.51.10.50.20.22.10.90.0
Total heroin consumption0.10.10.3-0.4-0.3-0.4-0.10.1-0.50.1-0.2-0.5
Area under the delay curve2.32.58.01.2-2.80.41.8-0.11.90.21.81.5
Delay disc. indifference point, 0s delay8.69.314.91.2-3.62.73.82.33.61.83.93.3
Delay disc. indifference point, 16s delay0.90.95.50.0-2.3-0.30.8-0.70.50.80.80.1
Delay disc. indifference point, 2s delay3.53.98.21.7-2.91.32.31.12.50.52.32.1
Delay disc. indifference point, 24s delay2.82.77.2-0.2-2.71.22.00.61.71.72.01.4
Delay disc. indifference point, 4s delay1.31.34.70.9-2.20.21.30.01.5-0.11.31.0
Delay disc. indifference point, 8s delay0.40.40.90.8-0.5-0.40.3-0.90.7-0.70.40.6
Delay discount exponential model param2.22.37.0-1.32.7-0.4-1.70.1-2.0-0.0-1.7-1.5
Delay discount hyperbolic model param2.62.77.6-1.42.8-0.5-1.9-0.1-2.2-0.1-1.9-1.7
Fecal boli incidents, locomotor time 10.50.51.10.20.4-0.4-0.8-0.7-1.10.4-0.8-1.1
Change in fecal boli incidents, locomotor task0.50.50.8-0.90.9-0.3-0.7-0.9-0.80.3-0.7-0.7
Time >=10cm from walls, locomotor time 13.43.45.41.0-0.72.12.22.31.91.12.22.1
Bouts of movement, locomotor time 10.70.81.30.1-0.41.11.10.61.10.81.11.1
Total resting periods, locomotor time 10.91.01.70.3-0.41.21.20.51.30.81.21.3
Rest time, locomotor task time 10.20.20.70.60.8-0.2-0.4-0.8-0.0-0.4-0.40.1
Distance moved, locomotor task time 10.00.00.1-0.2-0.2-0.2-0.10.1-0.3-0.3-0.1-0.3
Vertical activity count, locomotor time 10.70.73.5-1.9-0.70.1-0.2-0.0-0.91.0-0.2-0.9
Time >=10cm from walls, locomotor time 20.20.20.5-0.60.10.50.30.50.10.70.30.2
Bouts of movement, locomotor time 20.60.61.20.5-0.30.50.81.11.1-0.00.91.0
Total resting periods, locomotor time 20.70.71.60.4-0.30.61.00.91.3-0.01.01.2
Rest time, locomotor task time 20.20.21.10.11.1-0.2-0.5-0.4-0.3-0.5-0.5-0.2
Distance moved, locomotor task time 20.10.10.20.0-0.10.40.30.50.20.20.30.2
Vertical activity count, locomotor time 20.50.51.7-1.1-1.10.50.40.4-0.11.30.4-0.3
Weight adjusted by age1.61.79.23.0-0.30.10.70.31.4-1.30.71.3
Seeking ratio, delayed vs. immediate footshock2.52.95.7-1.90.2-1.7-1.7-1.6-2.20.2-1.8-2.4
Locomotion in novel chamber1.21.53.81.5-0.01.31.22.01.10.51.21.2
Locomotion in novel chamber post-restriction0.81.03.2-1.10.61.40.80.50.41.80.80.6
Progressive ratio0.10.10.20.5-0.4-0.1-0.00.1-0.2-0.1-0.0-0.3
Food seeking constrained by brief footshock0.50.63.0-0.4-1.70.00.50.40.9-0.40.80.6
Seeking ratio, punishment vs. effort0.10.20.6-0.3-0.4-0.4-0.0-0.20.6-0.70.10.4
Run reversals in cocaine runway, females2.52.54.7-0.6-0.72.21.81.71.31.92.01.4
Run reversals in cocaine runway, males0.30.31.0-1.00.2-0.5-0.5-0.2-0.2-0.7-0.4-0.2
Latency to leave start box in cocaine runway0.50.60.90.2-0.80.80.80.40.80.90.90.7
Latency to leave start box in cocaine runway, F1.11.22.81.7-0.00.70.90.81.4-0.71.01.4
Latency to leave start box in cocaine runway, M1.41.44.3-1.7-1.10.0-0.6-1.1-0.92.1-0.3-1.2
Cd content in liver0.30.41.0-0.30.61.00.40.70.40.50.40.6
Co content in liver0.40.40.90.5-1.00.40.80.30.70.70.80.5
Cu content in liver0.30.41.3-0.5-1.10.50.50.40.11.10.50.0
Fe content in liver1.41.62.7-1.40.8-0.7-1.3-1.5-1.60.8-1.3-1.6
K content in liver0.80.82.6-0.2-1.60.51.00.90.90.51.00.6
Mg content in liver0.40.41.80.5-1.3-0.50.40.10.6-0.50.40.3
Mn content in liver0.20.20.6-0.8-0.8-0.10.00.2-0.20.40.0-0.4
Na content in liver0.70.73.30.3-1.8-0.80.2-1.60.30.10.2-0.1
Rb content in liver0.30.31.21.0-1.1-0.10.4-0.30.4-0.10.40.2
Se content in liver0.60.71.8-0.3-1.1-1.3-0.7-0.6-0.6-0.7-0.7-0.9
Sr content in liver1.41.33.00.70.9-1.4-1.1-1.7-0.6-1.5-1.1-0.6
Zn content in liver2.93.25.2-0.01.1-2.3-2.1-1.6-1.6-2.3-2.1-1.6