| # | tissue | modality | RNA phenotype | h2 | h2 se | h2 P | eQTL R2 | BLUP R2 | ENET R2 | LASSO R2 | eQTL P | BLUP P | ENET P | LASSO P |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | gene expression | ENSRNOG00000019419 | 0.1200 | 0.0610 | 5.1e-14 | 0.103 | 0.099 | 0.096 | 0.100 | 1.5e-11 | 3.9e-11 | 8.1e-11 | 3.4e-11 |
| 2 | BLA | mRNA stability | ENSRNOG00000019419 | 0.1400 | 0.0770 | 3.7e-07 | 0.127 | 0.127 | 0.108 | 0.131 | 2.6e-07 | 2.7e-07 | 2.2e-06 | 1.7e-07 |
| 3 | Brain | gene expression | ENSRNOG00000019419 | 0.1000 | 0.0570 | 4.6e-10 | 0.102 | 0.105 | 0.106 | 0.104 | 1.0e-09 | 6.3e-10 | 5.0e-10 | 7.1e-10 |
| 4 | Brain | intron excision ratio | chr1:205676766:205677061 | 0.0297 | 0.0203 | 1.8e-03 | 0.027 | 0.027 | 0.022 | 0.024 | 1.5e-03 | 1.4e-03 | 3.6e-03 | 2.5e-03 |
| 5 | Brain | intron excision ratio | chr1:205676766:205677234 | 0.0267 | 0.0187 | 3.6e-03 | 0.024 | 0.021 | 0.016 | 0.018 | 2.6e-03 | 4.1e-03 | 1.1e-02 | 7.6e-03 |
| 6 | Brain | mRNA stability | ENSRNOG00000019419 | 0.0943 | 0.0547 | 6.2e-08 | 0.075 | 0.082 | 0.066 | 0.079 | 1.9e-07 | 4.6e-08 | 9.9e-07 | 9.0e-08 |
| 7 | IL | gene expression | ENSRNOG00000019419 | 0.2430 | 0.1220 | 1.7e-05 | 0.194 | 0.144 | 0.118 | 0.179 | 2.1e-05 | 2.5e-04 | 9.5e-04 | 4.4e-05 |
| 8 | LHb | gene expression | ENSRNOG00000019419 | 0.1765 | 0.1012 | 1.0e-03 | 0.125 | 0.027 | 0.016 | 0.039 | 7.0e-04 | 7.7e-02 | 1.4e-01 | 4.3e-02 |
| 9 | Liver | gene expression | ENSRNOG00000019419 | 0.1200 | 0.0800 | 2.6e-10 | 0.073 | 0.074 | 0.077 | 0.076 | 1.5e-08 | 1.3e-08 | 6.6e-09 | 7.6e-09 |
| 10 | NAcc | gene expression | ENSRNOG00000019419 | 0.0510 | 0.0320 | 7.7e-05 | 0.067 | 0.060 | 0.049 | 0.068 | 1.0e-05 | 3.0e-05 | 1.5e-04 | 8.8e-06 |
| 11 | NAcc | mRNA stability | ENSRNOG00000019419 | 0.0866 | 0.0510 | 6.7e-06 | 0.059 | 0.069 | 0.061 | 0.052 | 3.2e-05 | 8.0e-06 | 2.5e-05 | 9.4e-05 |
| 12 | PL | gene expression | ENSRNOG00000019419 | 0.0799 | 0.0459 | 1.0e-07 | 0.089 | 0.104 | 0.102 | 0.097 | 2.6e-07 | 2.7e-08 | 3.7e-08 | 7.9e-08 |
| 13 | PL | mRNA stability | ENSRNOG00000019419 | 0.1707 | 0.0938 | 1.1e-11 | 0.124 | 0.159 | 0.161 | 0.161 | 1.1e-09 | 3.6e-12 | 2.9e-12 | 2.6e-12 |
All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, the gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method.
| Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 |
|---|
Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Tibialis anterior weight | 9.1 | 31.4 | 37.7 | -6.0 | 2.4 | -5.8 | 6.1 | -6.1 | 5.7 | -6.1 | -5.6 | -5.5 | -5.5 | 5.4 | -6.0 | 5.6 |
| Delay discounting total patch changes 24 sec | 7.1 | 8.9 | 10.9 | -3.2 | 1.7 | -3.0 | 3.2 | -3.2 | 3.1 | -3.3 | -3.0 | -2.8 | -2.8 | 2.8 | -3.1 | 3.0 |
| Pavlov. Cond. magazine entry number | 6.3 | 7.8 | 10.6 | 3.3 | -1.4 | 2.9 | -3.0 | 3.1 | -3.1 | 2.5 | 2.5 | 2.6 | 2.5 | -3.1 | 3.0 | -2.8 |
| Extensor digitorum longus weight | 6.1 | 24.5 | 29.5 | -5.2 | 2.9 | -5.0 | 5.4 | -5.3 | 5.2 | -5.2 | -5.1 | -4.1 | -5.2 | 4.5 | -5.3 | 5.4 |
| Delay discounting total patch changes 12 sec | 5.8 | 7.7 | 10.1 | -3.1 | 0.9 | -2.9 | 3.0 | -3.1 | 2.8 | -3.2 | -2.5 | -3.0 | -2.4 | 2.9 | -3.0 | 2.4 |
| Sr content in liver | 5.2 | 4.8 | 5.9 | -2.4 | 0.5 | -2.3 | 2.3 | -2.4 | 2.2 | -2.3 | -2.2 | -2.4 | -2.1 | 2.2 | -2.3 | 1.9 |
| Reaction time premature initiations | 4.6 | 6.6 | 12.2 | -2.7 | 0.6 | -3.1 | 2.8 | -2.7 | 2.1 | -2.6 | -3.2 | -0.9 | -3.5 | 1.3 | -3.0 | 2.7 |
| One hour access (shock baseline) | 4.3 | 5.0 | 8.9 | 2.4 | -0.0 | 3.0 | -2.4 | 2.3 | -1.5 | 2.6 | 2.8 | 0.4 | 3.0 | -0.7 | 2.9 | -2.0 |
| Bone: trabecular tissue density | 4.3 | 6.1 | 9.0 | 2.6 | -2.2 | 2.4 | -2.6 | 2.6 | -2.7 | 2.3 | 2.3 | 1.6 | 2.5 | -2.5 | 2.5 | -3.0 |
| Zn content in liver | 4.0 | 4.5 | 5.7 | -2.2 | 1.4 | -2.0 | 2.3 | -2.3 | 2.4 | -2.2 | -2.0 | -2.0 | -1.8 | 2.4 | -2.1 | 2.2 |
| Reaction time premature initiation rate | 3.8 | 5.0 | 8.8 | -2.3 | 1.0 | -2.5 | 2.5 | -2.3 | 2.1 | -2.3 | -2.7 | -0.5 | -3.0 | 1.3 | -2.6 | 2.6 |
| Pavlov. Cond. magazine entry latency | 3.7 | 4.3 | 5.9 | -2.4 | 0.7 | -2.3 | 2.3 | -2.4 | 2.2 | -1.8 | -2.0 | -1.7 | -2.0 | 2.2 | -2.3 | 2.0 |
| Extinction: sum of active levers before priming | 3.7 | 3.8 | 5.1 | -2.2 | 0.8 | -2.1 | 2.1 | -2.3 | 2.0 | -1.7 | -1.9 | -2.0 | -1.8 | 2.0 | -2.0 | 1.7 |
| Body weight | 3.4 | 14.4 | 20.7 | -3.9 | 2.8 | -3.7 | 4.1 | -3.8 | 4.0 | -4.1 | -3.9 | -2.5 | -4.2 | 3.3 | -4.0 | 4.5 |
| One hour access (0.3 mA shock) | 3.2 | 3.8 | 6.7 | 2.2 | 0.2 | 2.6 | -2.1 | 2.2 | -1.5 | 2.1 | 2.3 | 1.3 | 2.3 | -1.1 | 2.4 | -1.5 |
| Indifference point function ln k | 3.1 | 4.4 | 10.9 | 2.3 | -0.7 | 1.7 | -2.1 | 2.3 | -2.4 | 1.7 | 1.1 | 3.3 | 1.2 | -3.2 | 2.0 | -1.8 |
| Indifference point function log k | 3.1 | 4.4 | 10.9 | 2.3 | -0.7 | 1.7 | -2.1 | 2.3 | -2.4 | 1.7 | 1.1 | 3.3 | 1.2 | -3.2 | 2.0 | -1.8 |
| Bone: maximum force | 3.1 | 5.4 | 9.6 | -2.2 | 3.1 | -1.5 | 2.3 | -2.2 | 2.9 | -1.7 | -1.7 | -2.2 | -1.7 | 2.9 | -1.8 | 3.0 |
| Total heroin consumption | 3.1 | 3.7 | 5.6 | -2.2 | -0.4 | -2.4 | 2.0 | -2.2 | 1.6 | -2.1 | -1.9 | -2.2 | -1.9 | 1.6 | -2.3 | 1.3 |
| Bone: maximum moment | 2.9 | 5.0 | 8.7 | -2.1 | 3.0 | -1.5 | 2.2 | -2.1 | 2.8 | -1.7 | -1.7 | -2.1 | -1.7 | 2.7 | -1.8 | 2.9 |
| Rest time, locomotor task time 2 | 2.9 | 3.4 | 4.4 | 1.9 | -0.8 | 2.0 | -2.1 | 2.1 | -1.9 | 1.8 | 1.9 | 1.4 | 2.0 | -1.8 | 2.1 | -1.8 |
| Pavlov. Cond. lever-magazine prob. diff. | 2.7 | 3.4 | 5.4 | -2.2 | 1.3 | -1.8 | 2.0 | -2.1 | 2.2 | -1.2 | -1.5 | -1.8 | -1.5 | 2.3 | -1.9 | 2.0 |
| Intermittent access day 15 total infusions | 2.7 | 3.0 | 5.8 | 1.8 | 0.5 | 2.4 | -1.9 | 1.9 | -1.1 | 2.0 | 2.3 | 0.8 | 2.2 | -0.6 | 2.3 | -1.3 |
| Latency to leave start box in cocaine runway, M | 2.7 | 2.6 | 3.5 | 1.7 | -0.3 | 1.9 | -1.8 | 1.9 | -1.5 | 1.8 | 1.7 | 1.4 | 1.5 | -1.4 | 1.9 | -1.5 |
| BMI with tail | 2.6 | 8.3 | 15.8 | -2.6 | 4.0 | -1.9 | 3.0 | -2.5 | 3.4 | -2.8 | -2.7 | -1.5 | -2.7 | 2.9 | -2.4 | 3.9 |
| Co content in liver | 2.6 | 3.1 | 8.0 | 1.4 | -2.8 | 0.7 | -1.7 | 1.4 | -2.3 | 1.2 | 0.7 | 2.1 | 0.9 | -2.6 | 1.2 | -2.2 |
| Soleus weight | 2.5 | 7.1 | 9.0 | 3.0 | -0.9 | 2.8 | -2.9 | 2.9 | -2.7 | 2.9 | 2.7 | 2.6 | 2.6 | -2.6 | 2.9 | -2.4 |
| Bone: cortical thickness | 2.5 | 4.1 | 6.6 | -2.2 | -0.5 | -2.6 | 2.2 | -2.3 | 1.6 | -2.2 | -2.4 | -1.4 | -2.5 | 1.2 | -2.4 | 1.6 |
| Active lever presses in extinction session 6 | 2.5 | 2.4 | 4.6 | -1.6 | 0.3 | -1.6 | 1.6 | -1.8 | 1.7 | -1.3 | -1.3 | -2.1 | -1.2 | 2.0 | -1.6 | 1.1 |
| Pavlov. Cond. index score | 2.4 | 3.1 | 5.2 | -2.1 | 1.3 | -1.6 | 1.8 | -2.0 | 2.1 | -1.1 | -1.4 | -1.8 | -1.4 | 2.3 | -1.7 | 1.9 |
| Locomotion velocity, session 2 | 2.4 | 2.9 | 3.9 | -1.7 | 1.2 | -1.6 | 1.9 | -1.6 | 1.8 | -2.0 | -1.5 | -1.4 | -1.7 | 1.6 | -1.8 | 2.0 |
| Glucose | 2.3 | 3.5 | 5.4 | 2.1 | 0.5 | 2.3 | -2.0 | 2.2 | -1.6 | 2.0 | 2.1 | 1.7 | 2.0 | -1.3 | 2.3 | -1.2 |
| Progressive ratio test 2 breakpoint | 2.3 | 2.6 | 4.5 | 1.7 | -0.2 | 2.1 | -1.7 | 1.7 | -1.2 | 1.8 | 2.1 | 0.8 | 2.0 | -0.7 | 2.0 | -1.4 |
| Short access day 10 total inactive lever presses | 2.3 | 2.5 | 4.3 | 1.8 | -0.7 | 1.6 | -1.6 | 1.7 | -1.8 | 1.3 | 1.3 | 2.1 | 1.3 | -2.0 | 1.6 | -1.5 |
| Distance traveled before self-admin | 2.3 | 2.4 | 4.0 | -1.7 | 0.9 | -1.5 | 1.6 | -1.8 | 1.8 | -1.2 | -1.3 | -2.0 | -1.3 | 1.9 | -1.5 | 1.5 |
| Locomotion in novel chamber post-restriction | 2.3 | 2.8 | 4.0 | 2.0 | -0.7 | 1.9 | -1.9 | 1.9 | -1.7 | 1.5 | 1.7 | 0.8 | 1.9 | -1.4 | 1.9 | -1.8 |
| Indifference point AUC | 2.2 | 2.5 | 5.2 | -1.8 | 0.8 | -1.4 | 1.6 | -1.8 | 1.8 | -1.4 | -1.0 | -2.3 | -0.9 | 2.3 | -1.5 | 1.3 |
| Pavlov. Cond. latency score | 2.2 | 2.8 | 4.9 | -1.9 | 1.4 | -1.4 | 1.7 | -1.8 | 2.0 | -1.1 | -1.2 | -1.7 | -1.2 | 2.2 | -1.6 | 1.9 |
| Bone surface | 2.2 | 3.8 | 6.4 | -1.9 | 2.4 | -1.3 | 1.9 | -2.0 | 2.4 | -1.5 | -1.3 | -2.5 | -1.2 | 2.5 | -1.6 | 2.2 |
| Saline control response | 2.1 | 2.8 | 4.8 | -1.8 | 0.3 | -2.0 | 1.8 | -1.8 | 1.5 | -1.7 | -1.9 | -1.1 | -2.2 | 1.1 | -1.9 | 1.7 |
| Progressive ratio test 1 breakpoint | 2.1 | 2.1 | 3.1 | 1.6 | -0.5 | 1.8 | -1.6 | 1.6 | -1.3 | 1.4 | 1.7 | 1.1 | 1.7 | -1.0 | 1.7 | -1.5 |
| Novel to familiar place preference ratio | 2.1 | 2.2 | 3.6 | -1.5 | 1.2 | -1.1 | 1.6 | -1.4 | 1.7 | -1.5 | -1.1 | -1.9 | -1.1 | 1.8 | -1.4 | 1.5 |
| Bone: final force | 2.1 | 3.4 | 5.1 | -1.9 | 1.9 | -1.6 | 1.9 | -1.8 | 2.2 | -1.6 | -1.6 | -1.8 | -1.6 | 2.1 | -1.7 | 2.3 |
| Time >=10cm from walls, locomotor time 1 | 2.1 | 2.1 | 4.0 | 1.6 | 0.9 | 2.0 | -1.5 | 1.4 | -0.7 | 1.8 | 2.0 | 0.2 | 1.9 | -0.1 | 1.8 | -1.0 |
| Mn content in liver | 2.1 | 2.4 | 4.1 | -1.6 | 1.0 | -1.4 | 1.6 | -1.5 | 1.7 | -1.5 | -1.2 | -2.0 | -1.5 | 1.8 | -1.5 | 1.5 |
| Length with tail | 2.0 | 7.4 | 9.8 | -2.9 | 0.8 | -3.1 | 3.0 | -2.9 | 2.6 | -3.0 | -2.8 | -2.1 | -3.1 | 2.2 | -3.1 | 2.8 |
| Conditioned reinforcement - actives | 2.0 | 1.9 | 3.3 | 1.4 | -0.6 | 1.6 | -1.5 | 1.4 | -1.1 | 1.7 | 1.8 | 0.2 | 1.8 | -0.5 | 1.7 | -1.5 |
| Bone: final moment | 2.0 | 3.3 | 5.1 | -1.9 | 1.8 | -1.5 | 1.9 | -1.8 | 2.1 | -1.6 | -1.5 | -1.8 | -1.6 | 2.0 | -1.7 | 2.2 |
| Length without tail | 1.9 | 4.1 | 5.7 | -2.2 | 1.1 | -2.1 | 2.2 | -2.2 | 2.1 | -1.9 | -2.0 | -1.7 | -2.1 | 2.0 | -2.1 | 2.4 |
| Retroperitoneal fat weight | 1.9 | 6.4 | 10.3 | 2.9 | 0.5 | 3.2 | -2.7 | 3.0 | -2.2 | 2.5 | 2.7 | 2.5 | 2.5 | -2.2 | 3.0 | -1.7 |
| Delay discounting water rate 12 sec | 1.9 | 2.8 | 7.0 | 1.6 | -1.6 | 1.0 | -1.6 | 1.8 | -2.1 | 1.4 | 0.7 | 2.5 | 0.6 | -2.6 | 1.3 | -1.7 |
| Stereotopy head waving duration, day 7 | 1.9 | 2.3 | 3.9 | -1.6 | 1.3 | -1.2 | 1.6 | -1.5 | 1.7 | -1.4 | -1.2 | -2.0 | -1.3 | 1.8 | -1.5 | 1.4 |
| Ambulatory time before self-admin | 1.9 | 2.0 | 4.3 | -1.4 | 0.8 | -1.2 | 1.4 | -1.6 | 1.7 | -0.9 | -0.9 | -2.0 | -0.9 | 2.1 | -1.3 | 1.3 |
| Progressive ratio test 1 active lever presses | 1.8 | 1.9 | 2.8 | 1.5 | -0.4 | 1.7 | -1.5 | 1.5 | -1.2 | 1.3 | 1.6 | 1.0 | 1.6 | -0.9 | 1.6 | -1.4 |
| Bone: connectivity density | 1.8 | 2.8 | 4.1 | -1.6 | 1.9 | -1.4 | 1.8 | -1.7 | 2.0 | -1.6 | -1.5 | -1.3 | -1.4 | 1.8 | -1.6 | 2.0 |
| Weight adjusted by age | 1.8 | 2.0 | 3.0 | -1.4 | 1.2 | -1.3 | 1.4 | -1.5 | 1.6 | -1.1 | -1.3 | -1.3 | -1.2 | 1.7 | -1.3 | 1.7 |
| Locomotion in novel chamber | 1.8 | 2.3 | 4.4 | 1.6 | 0.4 | 2.0 | -1.6 | 1.5 | -0.9 | 2.0 | 2.1 | 0.7 | 1.9 | -0.3 | 1.9 | -1.0 |
| Pavlov. Cond. intertrial magazine entries | 1.7 | 2.1 | 2.9 | 1.6 | -0.8 | 1.6 | -1.6 | 1.6 | -1.5 | 1.4 | 1.6 | 0.6 | 1.6 | -1.2 | 1.6 | -1.7 |
| Bone: endosteal perimeter | 1.7 | 3.5 | 7.4 | 1.7 | 2.5 | 2.7 | -1.7 | 1.8 | -0.5 | 2.2 | 2.4 | 0.6 | 2.4 | 0.2 | 2.4 | -0.3 |
| Delta time in closed arm before/after self-admin | 1.7 | 1.6 | 3.6 | -1.0 | 0.4 | -1.4 | 1.3 | -1.0 | 0.8 | -1.9 | -1.8 | 0.5 | -1.8 | -0.1 | -1.5 | 1.4 |
| Delta time in open arm before/after self-admin | 1.7 | 1.6 | 3.9 | -1.3 | 0.8 | -1.0 | 1.2 | -1.4 | 1.5 | -0.9 | -0.7 | -2.0 | -0.6 | 1.9 | -1.1 | 1.0 |
| Tibia length | 1.6 | 4.5 | 10.4 | -2.0 | 2.0 | -1.3 | 2.0 | -2.0 | 2.6 | -1.8 | -1.0 | -3.2 | -1.2 | 3.2 | -1.7 | 2.0 |
| Conditioned locomotion | 1.6 | 1.9 | 3.7 | 1.5 | 0.4 | 1.9 | -1.5 | 1.5 | -0.9 | 1.5 | 1.6 | 0.9 | 1.6 | -0.7 | 1.8 | -1.1 |
| Intermitt. access day 1 inactive lever presses | 1.6 | 1.7 | 2.9 | 1.7 | 0.1 | 1.7 | -1.4 | 1.5 | -1.1 | 1.4 | 1.5 | 0.8 | 1.5 | -0.8 | 1.6 | -1.1 |
| Breakpoint value in progressive ratio session | 1.6 | 1.8 | 3.5 | -1.6 | -0.1 | -1.5 | 1.4 | -1.5 | 1.3 | -1.3 | -1.1 | -1.9 | -1.1 | 1.5 | -1.5 | 0.9 |
| Pavlov. Cond. change in total contacts | 1.4 | 1.9 | 4.2 | -1.7 | 1.2 | -1.1 | 1.3 | -1.5 | 1.7 | -0.6 | -0.7 | -1.8 | -0.8 | 2.1 | -1.2 | 1.4 |
| Pavlov. Cond. response bias | 1.4 | 1.9 | 3.0 | -1.7 | 0.7 | -1.4 | 1.5 | -1.6 | 1.6 | -0.9 | -1.2 | -1.3 | -1.2 | 1.6 | -1.4 | 1.4 |
| Intermittent access intake day 1-15 change | 1.4 | 1.4 | 2.5 | 1.0 | -1.2 | 1.1 | -1.3 | 1.0 | -1.0 | 1.4 | 1.6 | -0.3 | 1.6 | -0.4 | 1.3 | -1.5 |
| Intermittent access standard deviation | 1.4 | 1.4 | 2.4 | 1.1 | -1.1 | 1.2 | -1.3 | 1.2 | -1.1 | 1.2 | 1.5 | 0.2 | 1.5 | -0.6 | 1.3 | -1.6 |
| Progressive ratio test 2 active lever presses | 1.4 | 1.5 | 3.1 | 1.3 | 0.4 | 1.8 | -1.3 | 1.3 | -0.7 | 1.3 | 1.7 | 0.5 | 1.6 | -0.3 | 1.6 | -0.9 |
| Total sessions with >9 infusions | 1.4 | 1.6 | 3.0 | 1.3 | 0.5 | 1.6 | -1.2 | 1.4 | -0.9 | 1.1 | 1.4 | 1.7 | 1.3 | -1.0 | 1.5 | -0.7 |
| Time in novel zone, hab. session 1 | 1.4 | 1.4 | 2.3 | 1.3 | -1.1 | 1.0 | -1.3 | 1.2 | -1.4 | 1.0 | 0.9 | 1.2 | 0.9 | -1.5 | 1.1 | -1.3 |
| Total zone transitions, hab. session 2 | 1.4 | 1.8 | 2.9 | -1.3 | 1.1 | -1.4 | 1.5 | -1.3 | 1.3 | -1.4 | -1.3 | -0.5 | -1.7 | 0.9 | -1.4 | 1.7 |
| Diff in mean of infusions in LGA sessions | 1.4 | 1.6 | 2.9 | -1.4 | -0.6 | -1.7 | 1.3 | -1.5 | 1.0 | -1.4 | -1.4 | -1.3 | -1.3 | 1.0 | -1.5 | 0.7 |
| Time in open arm before self-admin | 1.4 | 1.4 | 4.9 | 1.1 | -1.4 | 0.4 | -0.9 | 1.1 | -1.6 | 0.2 | 0.1 | 2.2 | 0.1 | -2.2 | 0.6 | -1.1 |
| Rest time, locomotor task time 1 | 1.4 | 1.6 | 2.1 | 1.0 | -1.1 | 1.2 | -1.3 | 1.4 | -1.4 | 1.2 | 1.4 | 0.8 | 1.4 | -1.2 | 1.2 | -1.4 |
| Delay discounting water rate 6 sec | 1.3 | 1.9 | 5.2 | 1.4 | -1.3 | 0.8 | -1.3 | 1.4 | -1.8 | 1.0 | 0.5 | 2.1 | 0.4 | -2.3 | 1.1 | -1.3 |
| Incentive salience index mean | 1.3 | 1.6 | 2.3 | -1.2 | 1.2 | -1.1 | 1.4 | -1.3 | 1.5 | -1.0 | -1.2 | -1.1 | -1.3 | 1.4 | -1.3 | 1.5 |
| Novelty place preference | 1.3 | 1.3 | 2.4 | -1.2 | 1.1 | -0.8 | 1.2 | -1.0 | 1.4 | -1.1 | -0.8 | -1.6 | -0.8 | 1.5 | -1.0 | 1.1 |
| Time in novel zone, NPP test | 1.3 | 1.4 | 2.2 | -1.2 | 1.1 | -0.9 | 1.2 | -1.0 | 1.4 | -1.2 | -0.9 | -1.4 | -0.9 | 1.5 | -1.1 | 1.2 |
| Pavlov. Cond. lever latency | 1.3 | 1.7 | 2.9 | 1.2 | -1.6 | 0.9 | -1.3 | 1.4 | -1.6 | 0.8 | 1.0 | 1.1 | 1.1 | -1.6 | 1.1 | -1.7 |
| K content in liver | 1.3 | 1.3 | 3.0 | -0.9 | 1.7 | -0.6 | 1.1 | -0.9 | 1.4 | -0.9 | -0.7 | -0.9 | -1.0 | 1.4 | -0.9 | 1.6 |
| Rb content in liver | 1.3 | 1.6 | 2.3 | 1.5 | -0.1 | 1.4 | -1.3 | 1.5 | -1.3 | 1.2 | 1.1 | 1.5 | 0.9 | -1.5 | 1.3 | -0.9 |
| Parametrial fat weight | 1.2 | 2.3 | 4.2 | 1.7 | 1.0 | 2.1 | -1.5 | 1.6 | -0.9 | 1.7 | 1.9 | 1.3 | 1.9 | -0.6 | 1.9 | -0.8 |
| Delay discounting total patch changes 6 sec | 1.2 | 1.8 | 2.7 | -1.5 | 0.9 | -1.4 | 1.4 | -1.3 | 1.3 | -1.7 | -1.4 | -0.9 | -1.3 | 1.1 | -1.4 | 1.4 |
| Delay discounting water rate 24 sec | 1.2 | 1.7 | 3.8 | 1.3 | -1.1 | 0.9 | -1.4 | 1.3 | -1.7 | 1.2 | 0.5 | 1.7 | 0.8 | -1.9 | 1.2 | -1.3 |
| Compulsive drug intake | 1.2 | 1.2 | 2.5 | -0.9 | -0.8 | -1.6 | 1.0 | -0.9 | 0.1 | -1.3 | -1.5 | 0.6 | -1.5 | -0.5 | -1.5 | 0.7 |
| Pavlov. Cond. magazine entry latency | 1.2 | 1.6 | 3.4 | -1.2 | 1.7 | -0.8 | 1.2 | -1.4 | 1.6 | -0.7 | -0.8 | -1.0 | -0.7 | 1.8 | -0.9 | 1.6 |
| Bone: marrow area | 1.2 | 2.6 | 5.6 | 1.6 | 2.4 | 2.3 | -1.4 | 1.7 | -0.5 | 1.8 | 1.8 | 1.1 | 1.9 | -0.2 | 2.0 | -0.1 |
| Sum of active levers in priming session hrs 5-6 | 1.2 | 1.2 | 5.9 | -1.1 | -0.1 | -0.9 | 0.9 | -1.2 | 1.1 | -0.5 | -0.3 | -2.4 | -0.2 | 1.8 | -0.9 | 0.3 |
| Locomotor testing distance | 1.1 | 1.8 | 6.0 | 1.3 | -1.3 | 0.5 | -1.1 | 1.3 | -1.8 | 0.6 | 0.1 | 2.3 | 0.1 | -2.4 | 0.8 | -1.1 |
| Locomotor testing rearing | 1.1 | 1.7 | 4.5 | 1.3 | -1.0 | 0.9 | -1.2 | 1.4 | -1.6 | 1.3 | 0.6 | 2.1 | 0.6 | -2.0 | 1.0 | -1.0 |
| Bone volume | 1.1 | 1.9 | 4.7 | -1.2 | 2.2 | -0.7 | 1.2 | -1.3 | 1.8 | -0.7 | -0.7 | -2.0 | -0.5 | 2.0 | -0.9 | 1.6 |
| Bone: endosteal estimation | 1.1 | 2.3 | 6.1 | 1.4 | 2.5 | 2.2 | -1.3 | 1.5 | -0.3 | 1.7 | 1.7 | 0.9 | 1.8 | -0.1 | 1.9 | 0.1 |
| Bone: post-yield work | 1.1 | 1.4 | 9.1 | 0.2 | 3.0 | 1.2 | -0.2 | 0.2 | 0.9 | 0.9 | 1.0 | -0.6 | 1.2 | 1.4 | 0.9 | 0.9 |
| Delta ambulatory time before/after self-admin | 1.1 | 1.2 | 2.5 | 1.0 | -1.2 | 0.7 | -1.1 | 1.1 | -1.4 | 0.9 | 0.7 | 1.5 | 0.7 | -1.6 | 0.9 | -1.2 |
| Bouts of movement, locomotor time 2 | 1.1 | 1.2 | 1.8 | -1.3 | 0.1 | -1.3 | 1.2 | -1.3 | 1.0 | -1.1 | -1.3 | -1.0 | -1.1 | 0.9 | -1.3 | 1.0 |
| Run reversals in cocaine runway, females | 1.1 | 1.1 | 2.3 | -0.8 | 1.2 | -0.9 | 1.1 | -0.7 | 0.8 | -1.2 | -1.3 | 0.5 | -1.4 | 0.1 | -1.0 | 1.5 |
| Cd content in liver | 1.1 | 1.2 | 2.3 | 0.9 | -0.3 | 1.2 | -1.2 | 1.1 | -1.0 | 1.2 | 1.2 | -0.0 | 1.5 | -0.7 | 1.3 | -1.3 |
| BMI without tail | 1.0 | 2.1 | 3.4 | -1.3 | 1.6 | -1.2 | 1.6 | -1.1 | 1.5 | -1.8 | -1.5 | -0.3 | -1.7 | 1.1 | -1.5 | 1.8 |
| Locomotor activity | 1.0 | 1.5 | 4.7 | 1.1 | -1.5 | 0.5 | -1.1 | 1.2 | -1.7 | 0.6 | 0.3 | 1.8 | 0.2 | -2.2 | 0.8 | -1.3 |
| Condit. Reinf. active-inactive response ratio | 1.0 | 1.1 | 2.6 | 0.8 | 1.1 | 1.5 | -0.8 | 0.8 | -0.1 | 1.0 | 1.6 | -0.8 | 1.6 | 0.6 | 1.2 | -0.7 |
| Condit. Reinf. active minus inactive responses | 1.0 | 1.1 | 1.3 | -1.1 | 0.5 | -1.1 | 1.1 | -1.1 | 1.1 | -0.9 | -1.0 | -1.1 | -1.1 | 1.1 | -1.1 | 1.0 |
| Condit. Reinf. active responses | 1.0 | 1.2 | 2.5 | -1.0 | 1.3 | -0.7 | 1.1 | -1.0 | 1.5 | -0.7 | -0.7 | -1.3 | -0.7 | 1.6 | -0.9 | 1.2 |
| Total zone transitions, NPP test | 1.0 | 1.5 | 2.5 | -1.2 | 0.5 | -1.3 | 1.4 | -1.2 | 1.2 | -1.6 | -1.2 | -1.1 | -1.3 | 0.8 | -1.4 | 1.2 |
| Bone: stiffness | 1.0 | 1.6 | 3.5 | -1.2 | 1.7 | -0.7 | 1.1 | -1.2 | 1.6 | -0.6 | -0.6 | -1.6 | -0.7 | 1.9 | -0.8 | 1.6 |
| Bone: trabecular number | 1.0 | 1.6 | 3.6 | -1.1 | 1.9 | -0.8 | 1.2 | -1.2 | 1.5 | -1.0 | -0.9 | -1.4 | -0.8 | 1.5 | -0.9 | 1.5 |
| Intermittent access intake escalation | 0.9 | 0.9 | 1.6 | 0.7 | -1.0 | 0.8 | -1.0 | 0.7 | -0.8 | 1.1 | 1.3 | -0.3 | 1.3 | -0.2 | 1.0 | -1.2 |
| Intermittent access day 1 total infusions | 0.9 | 1.1 | 4.3 | 0.9 | 2.1 | 1.6 | -0.6 | 1.0 | 0.1 | 0.7 | 1.0 | 0.9 | 0.9 | 0.0 | 1.2 | 0.3 |
| Intermittent access total infusions | 0.9 | 1.0 | 2.4 | 0.9 | 1.3 | 1.5 | -0.8 | 0.9 | -0.0 | 1.0 | 1.3 | 0.3 | 1.2 | 0.3 | 1.3 | -0.1 |
| Intermittent access total locomotion | 0.9 | 1.0 | 7.1 | 0.2 | 2.7 | 1.0 | 0.1 | 0.2 | 1.1 | 0.2 | 0.5 | -0.4 | 0.5 | 1.2 | 0.6 | 1.0 |
| Baseline Anxiety | 0.9 | 1.0 | 1.6 | -1.0 | 0.1 | -1.3 | 1.1 | -1.1 | 0.8 | -1.1 | -1.2 | -0.6 | -1.2 | 0.6 | -1.2 | 0.8 |
| Degree of sensitization stereotypy | 0.9 | 1.0 | 2.7 | -1.0 | 0.9 | -0.6 | 1.0 | -0.9 | 1.3 | -0.8 | -0.4 | -1.6 | -0.5 | 1.5 | -0.9 | 0.9 |
| Bone: cortical area | 0.9 | 1.3 | 2.3 | -1.2 | 1.3 | -0.8 | 1.1 | -1.2 | 1.4 | -0.8 | -0.8 | -1.3 | -0.9 | 1.5 | -0.9 | 1.4 |
| Time to tail flick, vehicle, before self-admin | 0.9 | 0.9 | 3.2 | -0.7 | 1.8 | -0.2 | 0.8 | -0.7 | 1.2 | -0.7 | -0.4 | -0.8 | -0.4 | 1.2 | -0.5 | 1.2 |
| Mean time between licks in bursts | 0.8 | 1.2 | 3.5 | -1.0 | -0.5 | -1.5 | 1.0 | -0.8 | 0.4 | -1.0 | -1.6 | 0.8 | -1.9 | -0.4 | -1.2 | 0.8 |
| Delay discounting water rate 18 sec | 0.8 | 1.0 | 3.9 | 0.9 | -0.6 | 0.4 | -0.8 | 1.0 | -1.3 | 0.8 | -0.1 | 1.9 | -0.1 | -2.0 | 0.6 | -0.5 |
| Condit. Reinf. lever presses | 0.8 | 1.1 | 1.9 | -1.2 | 0.9 | -0.9 | 1.1 | -1.1 | 1.3 | -0.7 | -0.7 | -1.3 | -0.8 | 1.4 | -1.0 | 1.2 |
| Conditioned reinforcement - inactives | 0.8 | 0.9 | 2.0 | 1.0 | 0.7 | 1.4 | -0.9 | 1.0 | -0.3 | 1.2 | 1.3 | 0.0 | 1.2 | 0.1 | 1.2 | -0.5 |
| Intermittent access terminal intake (last 3 days) | 0.8 | 0.8 | 2.2 | 0.6 | 1.5 | 1.4 | -0.6 | 0.7 | 0.3 | 0.9 | 1.2 | -0.3 | 1.1 | 0.7 | 1.1 | 0.0 |
| Lifetime Intake | 0.8 | 0.9 | 2.1 | 0.9 | 1.2 | 1.5 | -0.8 | 1.0 | -0.2 | 0.8 | 1.2 | 0.8 | 1.1 | -0.1 | 1.2 | -0.1 |
| Short access day 1 total infusions | 0.8 | 0.9 | 2.1 | 1.0 | 0.6 | 1.2 | -0.9 | 1.1 | -0.6 | 0.8 | 1.0 | 1.4 | 0.9 | -0.8 | 1.1 | -0.3 |
| Condit. Reinf. lever presses | 0.8 | 1.1 | 2.1 | -0.9 | 1.4 | -0.8 | 1.1 | -1.0 | 1.3 | -0.6 | -0.8 | -0.8 | -1.0 | 1.2 | -0.9 | 1.4 |
| Pavlov. Cond. lever-magazine prob. diff. | 0.8 | 1.1 | 2.3 | -1.1 | 1.0 | -0.7 | 1.0 | -1.2 | 1.3 | -0.5 | -0.6 | -1.2 | -0.6 | 1.5 | -0.8 | 1.2 |
| Pavlov. Cond. response bias | 0.8 | 0.9 | 2.3 | -1.0 | 1.0 | -0.7 | 0.9 | -1.1 | 1.3 | -0.4 | -0.5 | -1.0 | -0.6 | 1.5 | -0.8 | 1.1 |
| Bone: elastic displacement | 0.8 | 0.9 | 2.0 | 0.8 | -1.4 | 0.4 | -0.8 | 0.8 | -1.2 | 0.5 | 0.4 | 1.4 | 0.4 | -1.4 | 0.5 | -1.1 |
| Change in fecal boli incidents, locomotor task | 0.8 | 0.7 | 2.8 | 1.0 | -0.3 | 0.5 | -0.7 | 1.1 | -1.0 | 0.1 | 0.2 | 1.7 | 0.1 | -1.5 | 0.6 | -0.5 |
| Heart weight | 0.7 | 1.0 | 3.1 | 1.2 | 0.1 | 1.0 | -1.0 | 1.1 | -1.0 | 0.6 | 0.7 | 1.8 | 0.8 | -1.3 | 1.1 | -0.5 |
| Tail length | 0.7 | 2.2 | 4.0 | -1.5 | -0.7 | -2.0 | 1.6 | -1.5 | 0.9 | -1.9 | -1.7 | -0.8 | -2.0 | 0.6 | -1.9 | 1.0 |
| Cocaine response after cond. corrected | 0.7 | 0.7 | 2.0 | 0.9 | -0.5 | 0.7 | -0.8 | 1.0 | -1.0 | 0.4 | 0.4 | 1.4 | 0.5 | -1.4 | 0.7 | -0.8 |
| Post-drug Anxiety | 0.7 | 0.8 | 2.7 | -0.9 | 0.4 | -0.7 | 0.8 | -0.9 | 1.0 | -0.6 | -0.6 | -1.7 | -0.6 | 1.3 | -0.7 | 0.6 |
| Progressive ratio test 2 inactive lever presses | 0.7 | 0.8 | 1.9 | 0.9 | 1.2 | 1.4 | -0.7 | 0.8 | -0.0 | 0.8 | 1.3 | 0.1 | 1.1 | 0.3 | 1.1 | -0.1 |
| Short access day 1 total inactive lever presses | 0.7 | 0.8 | 1.7 | 1.0 | 0.8 | 1.2 | -0.8 | 1.0 | -0.5 | 0.8 | 0.9 | 1.3 | 0.8 | -0.7 | 1.0 | -0.4 |
| Time in familiar zone, hab. session 2 | 0.7 | 0.7 | 2.6 | 0.4 | -1.4 | -0.1 | -0.7 | 0.4 | -1.0 | 1.0 | 0.1 | 1.6 | -0.1 | -1.2 | 0.3 | -0.6 |
| Time in novel zone, hab. session 2 | 0.7 | 0.7 | 1.8 | -0.6 | 1.3 | -0.3 | 0.8 | -0.6 | 1.0 | -1.0 | -0.5 | -1.1 | -0.4 | 1.0 | -0.6 | 0.9 |
| Bone: elastic work | 0.7 | 1.0 | 2.1 | -1.0 | -0.3 | -1.3 | 1.0 | -0.9 | 0.5 | -1.3 | -1.5 | 0.2 | -1.3 | 0.0 | -1.2 | 0.8 |
| Bone: minimum diameter | 0.7 | 1.4 | 6.1 | 0.9 | 2.5 | 1.6 | -0.8 | 1.0 | 0.1 | 1.2 | 1.2 | 0.5 | 1.2 | 0.4 | 1.3 | 0.5 |
| Delta distance traveled before/after self-admin | 0.7 | 0.7 | 1.5 | 0.7 | -0.8 | 0.5 | -0.8 | 0.8 | -1.1 | 0.8 | 0.5 | 1.2 | 0.5 | -1.2 | 0.7 | -0.9 |
| Mg content in liver | 0.7 | 0.7 | 3.2 | -0.4 | 1.8 | -0.2 | 0.7 | -0.4 | 1.1 | -0.6 | -0.4 | -0.7 | -0.6 | 1.0 | -0.5 | 1.3 |
| Na content in liver | 0.7 | 0.7 | 1.6 | -0.7 | 1.0 | -0.5 | 0.8 | -0.8 | 1.1 | -0.7 | -0.5 | -1.2 | -0.5 | 1.3 | -0.7 | 0.9 |
| Delay discounting time to switch 0 sec | 0.6 | 0.9 | 2.4 | -0.7 | 1.6 | -0.3 | 0.8 | -0.9 | 1.3 | -0.5 | -0.4 | -1.0 | -0.2 | 1.5 | -0.5 | 1.2 |
| Reaction time num false alarms | 0.6 | 0.8 | 2.8 | 0.5 | -1.4 | 0.0 | -0.5 | 0.7 | -1.1 | -0.0 | -0.2 | 1.7 | -0.1 | -1.6 | 0.2 | -0.9 |
| Intermittent access day 1 locomotion | 0.6 | 0.6 | 4.9 | 0.3 | 2.2 | 0.8 | 0.0 | 0.3 | 0.5 | -0.1 | 0.2 | 0.9 | 0.2 | 0.2 | 0.5 | 0.9 |
| Short access total locomotion | 0.6 | 0.6 | 3.3 | -0.3 | 1.8 | -0.0 | 0.6 | -0.4 | 1.0 | -0.7 | -0.4 | 0.2 | -0.4 | 0.7 | -0.3 | 1.3 |
| Locomotion velocity, session 3 | 0.6 | 0.7 | 3.4 | -0.3 | 1.8 | -0.3 | 0.7 | -0.4 | 0.9 | -0.7 | -0.7 | -0.1 | -0.8 | 0.5 | -0.4 | 1.4 |
| Pavlov. Cond. change in total contacts | 0.6 | 0.6 | 2.2 | -0.6 | 1.3 | -0.1 | 0.5 | -0.7 | 1.1 | 0.1 | 0.0 | -1.2 | 0.1 | 1.5 | -0.3 | 0.7 |
| Pavlov. Cond. index score | 0.6 | 0.8 | 1.8 | -1.0 | 0.9 | -0.7 | 0.9 | -1.1 | 1.2 | -0.3 | -0.6 | -1.0 | -0.6 | 1.3 | -0.7 | 1.0 |
| Pavlov. Cond. latency score | 0.6 | 0.7 | 1.3 | -0.9 | 1.0 | -0.6 | 0.8 | -1.0 | 1.1 | -0.3 | -0.6 | -0.7 | -0.6 | 1.1 | -0.7 | 1.1 |
| Pavlov. Cond. magazine entry number | 0.6 | 0.8 | 2.1 | 1.0 | -0.5 | 0.7 | -0.8 | 1.2 | -1.1 | 0.4 | 0.5 | 1.2 | 0.4 | -1.5 | 0.8 | -0.7 |
| Bone: trabecular spacing | 0.6 | 0.8 | 2.9 | 0.6 | -1.7 | 0.2 | -0.7 | 0.6 | -1.2 | 0.8 | 0.4 | 1.2 | 0.1 | -1.4 | 0.4 | -0.8 |
| Time to tail flick, test, before self-admin | 0.6 | 0.6 | 2.4 | -0.6 | 1.5 | -0.3 | 0.7 | -0.4 | 0.7 | -0.9 | -0.8 | 0.2 | -0.8 | 0.3 | -0.5 | 1.2 |
| Run reversals in cocaine runway, males | 0.6 | 0.6 | 0.9 | 0.8 | -0.7 | 0.6 | -0.8 | 0.8 | -0.9 | 0.6 | 0.7 | 0.6 | 0.7 | -0.9 | 0.7 | -0.9 |
| Se content in liver | 0.6 | 0.7 | 3.6 | -0.5 | 1.3 | 0.0 | 0.5 | -0.5 | 1.0 | -0.3 | 0.1 | -1.9 | 0.1 | 1.5 | -0.2 | 0.6 |
| Indifference point 0 sec | 0.5 | 0.8 | 1.3 | -0.9 | 0.6 | -0.9 | 1.0 | -0.8 | 0.9 | -1.1 | -0.9 | -1.0 | -0.9 | 0.7 | -0.9 | 1.0 |
| Delay discounting total patch changes 0 sec | 0.5 | 0.8 | 1.5 | -0.9 | 0.1 | -1.0 | 0.9 | -0.8 | 0.7 | -1.2 | -1.1 | -0.7 | -1.1 | 0.4 | -1.0 | 0.8 |
| Delay discounting total patch changes 18 sec | 0.5 | 0.7 | 2.0 | -1.0 | 0.1 | -0.8 | 0.8 | -0.9 | 0.7 | -1.0 | -0.6 | -1.4 | -0.4 | 0.9 | -0.8 | 0.4 |
| Delay discounting water rate 0 sec | 0.5 | 0.7 | 1.6 | 0.7 | -1.0 | 0.5 | -0.9 | 0.9 | -1.1 | 0.8 | 0.4 | 0.9 | 0.4 | -1.3 | 0.7 | -1.0 |
| Light reinforcement 2 | 0.5 | 0.6 | 1.4 | 0.5 | 0.8 | 1.0 | -0.4 | 0.3 | 0.3 | 0.9 | 1.0 | -1.1 | 1.2 | 1.0 | 0.8 | 0.2 |
| Reaction time number correct | 0.5 | 0.7 | 1.8 | -0.9 | -0.1 | -1.2 | 0.8 | -0.8 | 0.5 | -0.7 | -1.1 | -0.4 | -1.3 | 0.2 | -1.0 | 0.8 |
| Reaction time trials correct on left | 0.5 | 0.7 | 1.8 | -0.9 | -0.1 | -1.2 | 0.8 | -0.8 | 0.5 | -0.7 | -1.1 | -0.4 | -1.3 | 0.2 | -1.0 | 0.8 |
| Reaction time trials on left | 0.5 | 0.7 | 1.8 | -1.0 | -0.2 | -1.2 | 0.8 | -0.8 | 0.5 | -0.7 | -1.2 | -0.4 | -1.3 | 0.2 | -1.0 | 0.8 |
| Reaction time trials completed | 0.5 | 0.7 | 1.8 | -1.0 | -0.2 | -1.2 | 0.8 | -0.8 | 0.5 | -0.7 | -1.2 | -0.4 | -1.3 | 0.2 | -1.0 | 0.8 |
| Conditioned locomotion | 0.5 | 0.6 | 1.1 | -0.9 | 0.4 | -0.8 | 0.9 | -0.8 | 0.8 | -1.1 | -0.8 | -0.4 | -0.8 | 0.6 | -0.9 | 0.8 |
| Cocaine response after cond. not corrected | 0.5 | 0.6 | 1.9 | 0.7 | -0.3 | 0.6 | -0.7 | 0.8 | -0.8 | 0.7 | 0.4 | 1.4 | 0.5 | -1.1 | 0.7 | -0.6 |
| Pavlov. Cond. lever latency | 0.5 | 0.7 | 1.2 | 0.9 | -1.1 | 0.6 | -0.8 | 0.8 | -1.0 | 0.4 | 0.5 | 0.7 | 0.6 | -1.0 | 0.6 | -1.1 |
| Short access day 10 total infusions | 0.5 | 0.5 | 3.2 | 0.4 | 1.8 | 1.0 | -0.2 | 0.5 | 0.3 | 0.3 | 0.6 | 0.8 | 0.4 | 0.2 | 0.7 | 0.5 |
| Short access total infusions | 0.5 | 0.5 | 1.6 | 0.7 | 1.1 | 1.0 | -0.4 | 0.7 | -0.1 | 0.3 | 0.6 | 1.3 | 0.5 | -0.4 | 0.7 | 0.1 |
| Locomotion distance, session 1 | 0.5 | 0.7 | 1.3 | -0.6 | 0.9 | -0.7 | 0.9 | -0.6 | 0.8 | -1.2 | -0.9 | -0.2 | -1.0 | 0.3 | -0.9 | 1.0 |
| Bone: cortical thickness | 0.5 | 0.6 | 1.3 | -0.7 | -0.7 | -1.2 | 0.7 | -0.8 | 0.2 | -0.8 | -1.1 | 0.3 | -1.1 | -0.1 | -0.9 | 0.3 |
| Bone: cortical tissue density | 0.5 | 0.7 | 1.1 | -0.8 | -0.8 | -1.1 | 0.8 | -0.9 | 0.5 | -1.0 | -0.8 | -0.9 | -0.7 | 0.5 | -1.0 | 0.2 |
| Time in closed arm after self-admin | 0.5 | 0.6 | 1.6 | 0.8 | -0.2 | 0.7 | -0.7 | 0.9 | -0.8 | 0.6 | 0.5 | 1.3 | 0.5 | -1.0 | 0.7 | -0.4 |
| Time to tail flick, vehicle, after self-admin | 0.5 | 0.5 | 1.1 | -0.6 | 0.8 | -0.7 | 0.7 | -0.6 | 0.6 | -0.8 | -0.9 | 0.1 | -0.9 | 0.2 | -0.7 | 1.0 |
| Vertical activity count, locomotor time 1 | 0.5 | 0.5 | 1.0 | 1.0 | -0.2 | 0.7 | -0.8 | 0.7 | -0.7 | 0.8 | 0.5 | 0.7 | 0.7 | -0.7 | 0.8 | -0.6 |
| Total resting periods, locomotor time 2 | 0.5 | 0.6 | 1.0 | -1.0 | 0.1 | -0.9 | 0.8 | -0.9 | 0.7 | -0.7 | -0.8 | -0.8 | -0.7 | 0.7 | -0.9 | 0.7 |
| Std. dev. time between licks in bursts | 0.4 | 0.5 | 2.7 | 0.3 | -0.9 | -0.2 | -0.3 | 0.4 | -0.7 | 0.2 | -0.3 | 1.6 | -0.4 | -1.2 | 0.1 | -0.3 |
| Water consumed over 24 hours | 0.4 | 0.4 | 0.9 | -0.8 | -0.4 | -0.9 | 0.6 | -0.6 | 0.3 | -0.6 | -0.7 | -0.4 | -0.9 | 0.2 | -0.8 | 0.5 |
| Reaction time mean minus median | 0.4 | 0.6 | 2.9 | -0.8 | -0.1 | -0.3 | 0.4 | -0.9 | 0.8 | -0.1 | 0.3 | -1.7 | 0.2 | 1.5 | -0.4 | 0.2 |
| Reaction time num false alarms AUC | 0.4 | 0.6 | 2.2 | -0.1 | -1.5 | -0.6 | 0.0 | 0.2 | -0.7 | -0.7 | -0.7 | 1.1 | -0.6 | -1.3 | -0.4 | -0.5 |
| Reaction time false alarm rate | 0.4 | 0.5 | 1.7 | 0.5 | -1.1 | 0.2 | -0.5 | 0.7 | -0.9 | -0.1 | 0.0 | 1.3 | 0.2 | -1.2 | 0.3 | -0.8 |
| Reaction time trials AUC | 0.4 | 0.6 | 1.6 | -0.8 | -0.1 | -1.1 | 0.7 | -0.7 | 0.4 | -0.6 | -1.1 | -0.3 | -1.3 | 0.0 | -0.9 | 0.7 |
| Condit. Reinf. active minus inactive responses | 0.4 | 0.5 | 1.2 | 0.6 | 0.1 | 0.9 | -0.7 | 0.6 | -0.4 | 0.9 | 1.1 | -0.4 | 1.0 | 0.1 | 0.8 | -0.7 |
| Intermitt. access day 15 inactive lever presses | 0.4 | 0.5 | 2.5 | -0.1 | 1.6 | 0.3 | 0.3 | -0.2 | 0.9 | 0.1 | 0.2 | -0.8 | 0.0 | 1.1 | 0.1 | 0.9 |
| Short access day 1 locomotion | 0.4 | 0.4 | 2.9 | -0.2 | 1.7 | 0.1 | 0.4 | -0.2 | 0.7 | -0.4 | -0.2 | 0.6 | -0.2 | 0.4 | -0.1 | 1.0 |
| Condit. Reinf. active-inactive response ratio | 0.4 | 0.4 | 0.7 | -0.7 | -0.3 | -0.9 | 0.6 | -0.7 | 0.5 | -0.7 | -0.8 | -0.7 | -0.7 | 0.3 | -0.8 | 0.2 |
| Bone: apparent density | 0.4 | 0.7 | 2.1 | -0.7 | 1.5 | -0.5 | 0.8 | -0.8 | 1.0 | -0.5 | -0.5 | -0.7 | -0.4 | 1.0 | -0.5 | 1.1 |
| Bone: cortical apparent density | 0.4 | 0.5 | 0.9 | -0.8 | -0.7 | -0.9 | 0.7 | -0.8 | 0.5 | -0.9 | -0.8 | -0.8 | -0.7 | 0.4 | -0.9 | 0.1 |
| Bone: maximum diameter | 0.4 | 0.7 | 2.8 | -0.5 | 1.7 | 0.1 | 0.5 | -0.5 | 1.0 | -0.1 | 0.1 | -1.3 | 0.1 | 1.4 | -0.1 | 1.0 |
| Bone: periosteal estimation | 0.4 | 0.9 | 6.3 | 0.0 | 2.5 | 0.8 | 0.0 | 0.1 | 0.8 | 0.5 | 0.5 | -0.5 | 0.6 | 1.2 | 0.5 | 1.1 |
| Delta time to tail flick, test, before/after SA | 0.4 | 0.3 | 2.1 | 0.2 | -1.4 | -0.0 | -0.4 | 0.1 | -0.5 | 0.4 | 0.5 | -0.5 | 0.5 | -0.1 | 0.1 | -0.9 |
| Delay disc. indifference point, 4s delay | 0.4 | 0.4 | 1.3 | -0.4 | 0.6 | -0.6 | 0.7 | -0.3 | 0.4 | -1.1 | -0.8 | 0.5 | -0.9 | -0.1 | -0.6 | 0.8 |
| Fecal boli incidents, locomotor time 1 | 0.4 | 0.5 | 1.2 | 0.3 | 0.3 | 0.8 | -0.5 | 0.1 | -0.0 | 1.0 | 1.1 | -0.7 | 1.1 | 0.6 | 0.7 | -0.4 |
| Distance moved, locomotor task time 2 | 0.4 | 0.4 | 0.8 | -0.7 | -0.4 | -0.9 | 0.7 | -0.8 | 0.5 | -0.5 | -0.7 | -0.6 | -0.7 | 0.5 | -0.8 | 0.3 |
| Epididymis fat weight | 0.3 | 0.7 | 1.5 | 0.9 | 1.2 | 1.2 | -0.7 | 1.0 | -0.3 | 0.8 | 0.9 | 0.9 | 0.5 | -0.3 | 1.0 | 0.3 |
| Liver weight, left | 0.3 | 0.5 | 0.9 | 0.5 | -0.6 | 0.6 | -0.7 | 0.7 | -0.9 | 0.5 | 0.5 | 1.0 | 0.5 | -0.9 | 0.7 | -0.6 |
| Std. dev. reaction times | 0.3 | 0.4 | 1.3 | 0.0 | -1.1 | 0.3 | -0.5 | -0.0 | -0.3 | 0.7 | 0.8 | -0.8 | 0.9 | 0.3 | 0.4 | -0.9 |
| Cocaine response before conditioning | 0.3 | 0.3 | 1.1 | -0.6 | 0.3 | -0.5 | 0.5 | -0.7 | 0.7 | 0.4 | -0.2 | -0.6 | -0.3 | 1.0 | -0.4 | 0.4 |
| Condit. Reinf. inactive responses | 0.3 | 0.4 | 1.0 | -0.4 | -1.0 | -0.8 | 0.3 | -0.3 | -0.2 | -0.2 | -0.9 | 0.7 | -1.0 | -0.6 | -0.6 | 0.3 |
| Pavlov. Cond. lever contacts | 0.3 | 0.4 | 0.8 | -0.9 | 0.3 | -0.7 | 0.6 | -0.8 | 0.7 | -0.2 | -0.4 | -0.7 | -0.5 | 0.8 | -0.6 | 0.6 |
| Intermitt. access escalation Index | 0.3 | 0.3 | 1.7 | 0.5 | 0.2 | 0.3 | -0.3 | 0.4 | -0.5 | 0.2 | 0.1 | 1.3 | 0.1 | -0.9 | 0.3 | -0.1 |
| Intermittent access day 15 total locomotion | 0.3 | 0.3 | 1.6 | 0.3 | 1.3 | 0.8 | -0.2 | 0.3 | 0.4 | 0.3 | 0.7 | -0.2 | 0.5 | 0.6 | 0.6 | 0.2 |
| Cocaine induced anxiety | 0.3 | 0.4 | 1.3 | -0.7 | 0.4 | -0.4 | 0.5 | -0.5 | 0.7 | -0.4 | -0.3 | -1.2 | -0.3 | 0.9 | -0.4 | 0.5 |
| Incentive Sensitization - Responses | 0.3 | 0.3 | 1.1 | -0.3 | 1.0 | 0.1 | 0.3 | -0.3 | 0.8 | -0.1 | 0.1 | -0.7 | -0.0 | 1.0 | -0.1 | 0.6 |
| Incentive Sensitization - Breakpoint | 0.3 | 0.3 | 1.1 | -0.2 | 1.0 | 0.2 | 0.2 | -0.2 | 0.7 | 0.0 | 0.2 | -0.6 | 0.1 | 0.9 | 0.1 | 0.6 |
| Context. condit. distance diff. score | 0.3 | 0.3 | 0.7 | 0.8 | 0.4 | 0.7 | -0.5 | 0.8 | -0.5 | 0.3 | 0.4 | 0.8 | 0.4 | -0.8 | 0.6 | -0.3 |
| Stereotopy head waving bouts, day 3 | 0.3 | 0.4 | 2.9 | 0.5 | 1.7 | 0.8 | -0.1 | 0.5 | 0.3 | -0.3 | 0.2 | 0.2 | 0.5 | 0.1 | 0.4 | 0.5 |
| Stereotopy head waving bouts, day 7 | 0.3 | 0.4 | 1.5 | -0.3 | 1.0 | 0.1 | 0.4 | -0.2 | 0.7 | -0.5 | 0.1 | -1.2 | 0.2 | 1.0 | -0.1 | 0.4 |
| Condit. Reinf. inactive responses | 0.3 | 0.4 | 1.9 | 0.0 | 1.4 | 0.5 | 0.1 | 0.0 | 0.6 | 0.5 | 0.6 | -0.4 | 0.4 | 0.9 | 0.3 | 0.6 |
| Pavlov. Cond. lever contacts | 0.3 | 0.4 | 1.0 | -0.6 | 1.0 | -0.4 | 0.6 | -0.7 | 0.8 | -0.1 | -0.4 | -0.3 | -0.5 | 0.8 | -0.4 | 1.0 |
| Bone: periosteal perimeter | 0.3 | 0.5 | 2.7 | -0.0 | 1.6 | 0.6 | -0.0 | 0.0 | 0.6 | 0.4 | 0.5 | -0.5 | 0.5 | 1.0 | 0.4 | 0.7 |
| Bone: trabecular thickness | 0.3 | 0.3 | 1.0 | 0.4 | 0.5 | 0.6 | -0.5 | 0.3 | -0.1 | 0.9 | 0.7 | 0.3 | 1.0 | 0.3 | 0.7 | -0.4 |
| Distance traveled after self-admin | 0.3 | 0.3 | 0.8 | -0.7 | 0.0 | -0.6 | 0.5 | -0.7 | 0.5 | -0.1 | -0.4 | -0.9 | -0.4 | 0.7 | -0.5 | 0.3 |
| Ambulatory time after self-admin | 0.3 | 0.3 | 1.0 | -0.7 | 0.6 | -0.3 | 0.4 | -0.6 | 0.7 | 0.2 | -0.1 | -1.0 | -0.1 | 1.0 | -0.3 | 0.5 |
| Delay disc. indifference point, 0s delay | 0.3 | 0.3 | 1.3 | 0.7 | 0.7 | 0.5 | -0.3 | 0.5 | -0.3 | -0.1 | -0.1 | 1.2 | 0.1 | -0.7 | 0.4 | 0.2 |
| Delay disc. indifference point, 8s delay | 0.3 | 0.4 | 1.1 | 0.6 | -0.4 | 0.4 | -0.5 | 0.7 | -0.8 | 0.0 | 0.2 | 0.9 | 0.1 | -1.1 | 0.4 | -0.5 |
| Bouts of movement, locomotor time 1 | 0.3 | 0.4 | 2.7 | -0.2 | -1.6 | -0.7 | 0.1 | -0.4 | -0.2 | -0.3 | 0.0 | -0.8 | -0.1 | 0.1 | -0.4 | -0.6 |
| Distance moved, locomotor task time 1 | 0.3 | 0.3 | 0.6 | -0.4 | 0.8 | -0.5 | 0.6 | -0.6 | 0.7 | -0.4 | -0.8 | -0.2 | -0.6 | 0.6 | -0.5 | 0.7 |
| Vertical activity count, locomotor time 2 | 0.3 | 0.4 | 2.2 | 0.3 | -1.5 | -0.4 | -0.2 | 0.0 | -0.7 | -0.1 | -0.4 | 0.6 | -0.3 | -0.9 | -0.2 | -0.5 |
| Seeking ratio, punishment vs. effort | 0.3 | 0.3 | 1.2 | 0.4 | -0.9 | -0.1 | -0.2 | 0.3 | -0.7 | -0.3 | -0.3 | 1.0 | -0.1 | -1.1 | -0.0 | -0.6 |
| Latency to leave start box in cocaine runway | 0.3 | 0.3 | 0.7 | 0.4 | 0.8 | 0.8 | -0.4 | 0.6 | -0.1 | 0.6 | 0.6 | 0.3 | 0.4 | -0.1 | 0.7 | -0.1 |
| Cu content in liver | 0.3 | 0.3 | 0.7 | -0.5 | -0.5 | -0.7 | 0.5 | -0.4 | 0.1 | -0.8 | -0.8 | -0.3 | -0.8 | -0.2 | -0.7 | 0.1 |
| Right kidney weight | 0.2 | 0.7 | 2.2 | -0.5 | 1.5 | -0.0 | 0.6 | -0.6 | 1.1 | -0.4 | 0.0 | -1.0 | 0.0 | 1.4 | -0.3 | 1.0 |
| Intraocular pressure | 0.2 | 0.2 | 0.6 | 0.3 | -0.8 | 0.2 | -0.4 | 0.3 | -0.5 | 0.4 | 0.7 | -0.7 | 0.4 | -0.2 | 0.3 | -0.7 |
| Times rat made contact with spout | 0.2 | 0.2 | 0.6 | -0.4 | -0.8 | -0.7 | 0.3 | -0.3 | -0.2 | -0.6 | -0.6 | 0.0 | -0.7 | -0.4 | -0.5 | 0.0 |
| Reaction time mean minus median AUC | 0.2 | 0.2 | 1.0 | -0.5 | -1.0 | -0.3 | 0.1 | -0.5 | 0.1 | 0.1 | 0.2 | -1.0 | 0.1 | 0.6 | -0.2 | -0.3 |
| Reaction time mean | 0.2 | 0.2 | 0.6 | -0.0 | -0.5 | 0.3 | -0.3 | -0.1 | 0.0 | 0.7 | 0.6 | -0.6 | 0.8 | 0.5 | 0.3 | -0.5 |
| Reaction time mean AUC | 0.2 | 0.3 | 0.9 | 0.1 | -0.4 | 0.4 | -0.4 | 0.0 | -0.1 | 0.9 | 0.8 | -0.5 | 0.9 | 0.4 | 0.4 | -0.5 |
| Reaction time omissions | 0.2 | 0.2 | 1.6 | -0.4 | -1.3 | -0.6 | 0.1 | -0.5 | -0.2 | -0.2 | -0.2 | -0.4 | 0.1 | -0.0 | -0.3 | -0.5 |
| Intermittent access intake escalation 2 | 0.2 | 0.2 | 1.3 | -0.0 | -0.5 | 0.0 | -0.1 | -0.1 | 0.1 | 0.3 | 0.5 | -1.1 | 0.5 | 0.6 | 0.2 | -0.5 |
| Short access day 10 total locomotion | 0.2 | 0.3 | 1.9 | -0.0 | 1.4 | 0.3 | 0.3 | -0.1 | 0.6 | -0.3 | -0.2 | 0.1 | -0.1 | 0.5 | 0.0 | 0.8 |
| Locomotion distance, session 2 | 0.2 | 0.3 | 1.0 | -0.3 | 0.1 | -0.5 | 0.5 | -0.3 | 0.3 | -1.0 | -0.6 | 0.1 | -0.7 | -0.0 | -0.6 | 0.6 |
| Stereotopy head waving duration, day 3 | 0.2 | 0.2 | 0.9 | 0.6 | 1.0 | 0.7 | -0.2 | 0.5 | -0.0 | -0.4 | 0.2 | -0.1 | 0.4 | -0.2 | 0.4 | -0.0 |
| Locomotion velocity, session 8 | 0.2 | 0.2 | 0.8 | 0.3 | -0.8 | -0.1 | -0.1 | 0.3 | -0.5 | -0.4 | -0.2 | 0.5 | -0.2 | -0.9 | -0.0 | -0.4 |
| Locomotion distance, session 8 | 0.2 | 0.3 | 0.9 | 0.7 | 1.0 | 0.8 | -0.3 | 0.7 | -0.2 | 0.1 | 0.6 | 0.4 | 0.4 | -0.4 | 0.6 | 0.0 |
| Degree of sensitization distance | 0.2 | 0.2 | 1.8 | 0.3 | 1.3 | 0.5 | -0.0 | 0.3 | 0.3 | -0.1 | 0.0 | 0.2 | 0.3 | 0.2 | 0.3 | 0.4 |
| Time in familiar zone, hab. session 1 | 0.2 | 0.2 | 0.4 | -0.4 | 0.6 | -0.3 | 0.3 | -0.3 | 0.4 | 0.1 | -0.4 | 0.5 | -0.4 | 0.3 | -0.3 | 0.6 |
| Total zone transitions, hab. session 1 | 0.2 | 0.3 | 0.8 | -0.5 | -0.1 | -0.5 | 0.6 | -0.4 | 0.5 | -0.9 | -0.4 | -0.8 | -0.5 | 0.4 | -0.6 | 0.3 |
| Locomotion velocity, hab. session 1 | 0.2 | 0.2 | 0.6 | -0.2 | 0.8 | 0.0 | 0.4 | -0.2 | 0.6 | -0.6 | 0.1 | -0.6 | 0.0 | 0.7 | -0.2 | 0.5 |
| Total locomotion distance, hab. session 2 | 0.2 | 0.3 | 1.0 | -0.2 | 1.0 | -0.2 | 0.5 | -0.2 | 0.5 | -0.5 | -0.2 | 0.3 | -0.5 | 0.3 | -0.3 | 1.0 |
| Locomotion velocity, hab. session 2 | 0.2 | 0.2 | 1.3 | -0.1 | 1.1 | 0.1 | 0.3 | -0.0 | 0.5 | -0.4 | 0.1 | 0.1 | -0.2 | 0.4 | -0.1 | 0.8 |
| Bone: tissue strength | 0.2 | 0.2 | 0.4 | 0.5 | -0.3 | 0.4 | -0.5 | 0.5 | -0.5 | 0.7 | 0.5 | 0.3 | 0.1 | -0.5 | 0.4 | -0.3 |
| Time in closed arm before self-admin | 0.2 | 0.2 | 0.4 | 0.0 | 0.5 | 0.4 | -0.1 | 0.1 | 0.2 | 0.6 | 0.5 | -0.6 | 0.5 | 0.6 | 0.3 | 0.1 |
| Delay disc. indifference point, 16s delay | 0.2 | 0.2 | 1.1 | -0.3 | 1.0 | -0.1 | 0.4 | -0.3 | 0.6 | -0.2 | -0.1 | -0.3 | -0.1 | 0.7 | -0.2 | 0.7 |
| Delay disc. indifference point, 2s delay | 0.2 | 0.2 | 0.6 | 0.4 | 0.8 | 0.7 | -0.3 | 0.5 | -0.1 | 0.3 | 0.4 | 0.5 | 0.5 | -0.1 | 0.5 | 0.0 |
| Delay disc. indifference point, 24s delay | 0.2 | 0.2 | 0.5 | -0.4 | -0.0 | -0.5 | 0.4 | -0.2 | 0.1 | -0.6 | -0.6 | 0.3 | -0.7 | -0.2 | -0.4 | 0.3 |
| Total resting periods, locomotor time 1 | 0.2 | 0.2 | 1.4 | -0.3 | -1.2 | -0.6 | 0.2 | -0.4 | 0.0 | -0.2 | 0.1 | -0.9 | -0.1 | 0.4 | -0.4 | -0.3 |
| Time >=10cm from walls, locomotor time 2 | 0.2 | 0.2 | 0.5 | 0.2 | -0.2 | 0.5 | -0.4 | 0.1 | -0.1 | 0.7 | 0.6 | -0.6 | 0.7 | 0.4 | 0.5 | -0.6 |
| Left kidney weight | 0.1 | 0.2 | 1.3 | -0.1 | 1.1 | 0.2 | 0.3 | -0.2 | 0.6 | -0.3 | 0.1 | -0.3 | 0.0 | 0.7 | -0.0 | 0.7 |
| Liver weight, right | 0.1 | 0.2 | 0.9 | -0.2 | 0.7 | 0.0 | 0.1 | -0.0 | 0.1 | 0.1 | -0.1 | 0.9 | -0.3 | -0.1 | -0.0 | 0.7 |
| Food consumed during 24 hour testing period | 0.1 | 0.1 | 0.5 | 0.0 | -0.0 | 0.3 | -0.4 | 0.2 | -0.2 | 0.7 | 0.7 | -0.2 | 0.4 | -0.0 | 0.4 | -0.2 |
| Mean num. licks in bursts | 0.1 | 0.1 | 0.7 | 0.0 | -0.8 | -0.1 | -0.2 | 0.1 | -0.4 | 0.0 | -0.1 | 0.4 | -0.1 | -0.6 | -0.0 | -0.4 |
| Light reinforcement 1 | 0.1 | 0.2 | 1.2 | 0.3 | -1.1 | 0.2 | -0.5 | 0.3 | -0.6 | 0.6 | 0.2 | 0.1 | 0.2 | -0.6 | 0.3 | -0.5 |
| Median of all reaction times | 0.1 | 0.1 | 0.3 | -0.2 | -0.1 | 0.0 | 0.0 | -0.3 | 0.3 | 0.4 | 0.2 | -0.5 | 0.5 | 0.6 | 0.0 | -0.1 |
| Social response proportion | 0.1 | 0.1 | 0.4 | -0.3 | 0.2 | -0.3 | 0.4 | -0.2 | 0.3 | -0.3 | -0.4 | -0.0 | -0.6 | 0.1 | -0.4 | 0.4 |
| Social responses | 0.1 | 0.2 | 0.9 | -0.2 | -1.0 | -0.5 | 0.1 | -0.2 | -0.3 | -0.2 | -0.5 | 0.1 | -0.5 | -0.4 | -0.4 | -0.1 |
| Social time | 0.1 | 0.2 | 1.2 | 0.1 | -1.1 | -0.1 | -0.2 | 0.2 | -0.6 | -0.1 | -0.1 | 0.2 | -0.2 | -0.7 | -0.1 | -0.3 |
| Condit. Reinf. lever reinforcers received | 0.1 | 0.1 | 0.5 | -0.4 | 0.0 | -0.2 | 0.2 | -0.3 | 0.3 | -0.1 | -0.0 | -0.7 | -0.2 | 0.5 | -0.3 | 0.2 |
| Progressive ratio test 1 inactive lever presses | 0.1 | 0.1 | 0.4 | -0.0 | 0.6 | -0.0 | 0.3 | -0.1 | 0.3 | -0.5 | -0.2 | 0.5 | -0.3 | 0.1 | -0.2 | 0.5 |
| Number of responses in last shaping day | 0.1 | 0.1 | 0.5 | -0.1 | -0.2 | -0.1 | -0.0 | 0.1 | -0.3 | -0.3 | -0.1 | 0.7 | -0.1 | -0.6 | -0.1 | -0.0 |
| Locomotion velocity, session 1 | 0.1 | 0.1 | 0.3 | 0.1 | -0.1 | -0.2 | 0.1 | 0.1 | -0.1 | -0.4 | -0.4 | 0.5 | -0.4 | -0.6 | -0.2 | -0.0 |
| Locomotion distance, session 3 | 0.1 | 0.1 | 0.4 | -0.2 | 0.2 | -0.4 | 0.2 | -0.2 | 0.0 | -0.1 | -0.3 | 0.3 | -0.6 | -0.2 | -0.2 | 0.5 |
| Locomotion velocity, session 7 | 0.1 | 0.1 | 0.8 | 0.3 | 0.9 | 0.4 | -0.1 | 0.2 | 0.2 | -0.2 | 0.1 | -0.2 | 0.4 | 0.2 | 0.2 | 0.3 |
| Locomotion distance, session 7 | 0.1 | 0.1 | 0.7 | 0.5 | 0.5 | 0.2 | -0.2 | 0.4 | -0.2 | -0.1 | -0.1 | 0.9 | 0.1 | -0.6 | 0.2 | 0.1 |
| Total locomotion distance, hab. session 1 | 0.1 | 0.2 | 0.9 | 0.3 | 0.9 | 0.6 | -0.1 | 0.4 | 0.2 | 0.0 | 0.6 | -0.1 | 0.6 | 0.3 | 0.4 | 0.1 |
| Total locomotion distance, NPP test | 0.1 | 0.1 | 0.5 | -0.0 | 0.5 | -0.2 | 0.3 | -0.1 | 0.3 | -0.7 | -0.2 | 0.1 | -0.3 | -0.0 | -0.3 | 0.5 |
| Pavlov. Cond. intertrial magazine entries | 0.1 | 0.1 | 0.9 | -0.0 | -0.5 | 0.1 | 0.0 | -0.0 | 0.1 | 0.1 | 0.4 | -1.0 | 0.3 | 0.4 | -0.1 | -0.3 |
| Bone: cortical porosity | 0.1 | 0.1 | 0.7 | 0.2 | -0.8 | 0.1 | -0.3 | 0.2 | -0.4 | -0.1 | 0.2 | -0.1 | 0.4 | -0.2 | 0.2 | -0.6 |
| Bone: cortical porosity | 0.1 | 0.1 | 0.8 | -0.2 | -0.9 | -0.3 | 0.1 | -0.2 | -0.2 | -0.5 | -0.3 | -0.3 | -0.0 | -0.1 | -0.2 | -0.5 |
| Time in open arm after self-admin | 0.1 | 0.2 | 0.9 | -0.2 | -1.0 | -0.5 | 0.1 | -0.2 | -0.2 | -0.4 | -0.3 | -0.1 | -0.2 | -0.3 | -0.3 | -0.5 |
| Time to tail flick, test, after self-admin | 0.1 | 0.1 | 0.1 | 0.3 | -0.2 | 0.3 | -0.3 | 0.3 | -0.3 | 0.3 | 0.3 | 0.1 | 0.4 | -0.3 | 0.3 | -0.3 |
| Delta time to tail flick, vehicle, before/after SA | 0.1 | 0.1 | 0.2 | 0.0 | -0.4 | -0.3 | 0.0 | -0.0 | -0.2 | -0.1 | -0.3 | 0.4 | -0.4 | -0.5 | -0.2 | 0.0 |
| Area under the delay curve | 0.1 | 0.1 | 0.4 | -0.0 | 0.6 | -0.0 | 0.2 | 0.0 | 0.2 | -0.4 | -0.2 | 0.3 | -0.2 | -0.1 | -0.1 | 0.4 |
| Delay discount exponential model param | 0.1 | 0.1 | 0.3 | 0.1 | -0.6 | 0.0 | -0.2 | -0.1 | -0.2 | 0.4 | 0.1 | -0.3 | 0.2 | 0.1 | 0.1 | -0.4 |
| Delay discount hyperbolic model param | 0.1 | 0.1 | 0.4 | 0.1 | -0.6 | 0.0 | -0.2 | -0.0 | -0.2 | 0.4 | 0.2 | -0.3 | 0.3 | 0.1 | 0.1 | -0.4 |
| Progressive ratio | 0.1 | 0.2 | 0.7 | -0.2 | 0.8 | 0.2 | 0.1 | 0.0 | 0.4 | 0.4 | 0.3 | -0.4 | -0.1 | 0.6 | 0.1 | 0.6 |
| Food seeking constrained by brief footshock | 0.1 | 0.2 | 0.6 | 0.5 | -0.4 | 0.1 | -0.3 | 0.4 | -0.5 | 0.2 | 0.1 | 0.8 | 0.0 | -0.8 | 0.2 | -0.2 |
| Number of licking bursts | 0.0 | 0.0 | 0.0 | 0.1 | 0.2 | 0.0 | -0.0 | 0.1 | -0.0 | -0.1 | 0.1 | -0.2 | -0.0 | -0.0 | 0.1 | 0.1 |
| Condit. Reinf. active responses | 0.0 | 0.0 | 0.2 | -0.0 | -0.0 | 0.1 | -0.1 | 0.0 | 0.0 | 0.2 | 0.2 | -0.4 | 0.0 | 0.1 | 0.0 | 0.0 |
| Locomotion velocity, NPP test | 0.0 | 0.0 | 0.4 | 0.1 | 0.2 | -0.1 | 0.2 | 0.0 | 0.1 | -0.6 | -0.0 | -0.0 | -0.1 | -0.1 | -0.2 | 0.2 |
| Seeking ratio, delayed vs. immediate footshock | 0.0 | 0.0 | 0.2 | -0.1 | 0.2 | -0.1 | 0.1 | -0.1 | 0.1 | -0.2 | -0.0 | 0.1 | -0.1 | -0.0 | -0.1 | 0.4 |
| Latency to leave start box in cocaine runway, F | 0.0 | 0.0 | 0.2 | -0.2 | 0.5 | 0.1 | 0.1 | -0.0 | 0.3 | -0.1 | 0.0 | -0.3 | -0.1 | 0.3 | -0.0 | 0.2 |
| Fe content in liver | 0.0 | 0.0 | 0.2 | 0.1 | 0.2 | 0.2 | -0.0 | 0.0 | 0.1 | -0.1 | 0.2 | -0.5 | 0.3 | 0.3 | 0.1 | -0.2 |
For each tested trait, stats based on TWAS chi2 (squared Z-score) for the above models are shown. Avg chi2 ratio is the mean chi2 across all models for this gene, divided by the mean chi2 across all models for all genes. Avg chi2 is the mean chi2 across all models for this gene. Max chi2 is the highest chi2 across all models for this gene.
The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.