Hub : Genes

P2ry6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000050227 0.02 0.02 8.9e-03 0 0 -0 0 3.5e-01 1.2e-01 5.1e-01 2.9e-01
2 Adipose alternative polyA ENSRNOT00000050227 0.03 0.02 3.2e-03 0 0 -0 0 2.8e-01 7.3e-02 6.2e-01 2.2e-01
3 Adipose alternative polyA ENSRNOT00000108172 0.03 0.02 2.7e-03 0 0.01 -0 0 2.6e-01 6.0e-02 6.2e-01 2.0e-01
4 Adipose alternative TSS ENSRNOT00000050227 0.15 0.14 1.1e-04 0.03 0.03 0.02 0.03 2.2e-04 3.9e-04 1.0e-03 2.7e-04
5 Adipose alternative TSS ENSRNOT00000108172 0.18 0.14 1.2e-05 0.04 0.04 0.03 0.04 4.5e-05 4.1e-05 2.0e-04 6.0e-05
6 Adipose gene expression ENSRNOG00000019270 0.2 0.09 0.0e+00 0.12 0.21 0.21 0.21 2.4e-13 6.7e-23 2.2e-23 3.7e-23
7 BLA gene expression ENSRNOG00000019270 0.39 0.15 2.6e-15 0.27 0.25 0.24 0.26 5.4e-15 1.4e-13 3.8e-13 2.4e-14
8 Brain gene expression ENSRNOG00000019270 0.24 0.11 0.0e+00 0.27 0.27 0.27 0.27 2.7e-25 1.1e-24 5.2e-25 2.1e-25
9 IL gene expression ENSRNOG00000019270 0.28 0.14 1.9e-04 0.06 0.11 0.06 0.09 1.5e-02 1.5e-03 1.7e-02 3.0e-03
10 LHb gene expression ENSRNOG00000019270 0.3 0.14 1.2e-05 0.06 0.17 0.19 0.18 1.8e-02 6.2e-05 3.4e-05 4.4e-05
11 Liver gene expression ENSRNOG00000019270 0.14 0.07 1.2e-11 0.07 0.08 0.08 0.07 2.9e-08 3.3e-09 6.2e-09 9.3e-09
12 NAcc gene expression ENSRNOG00000019270 0.22 0.09 0.0e+00 0.25 0.25 0.27 0.28 5.6e-19 8.4e-19 5.5e-20 9.1e-21
13 OFC gene expression ENSRNOG00000019270 0.36 0.15 2.1e-07 0.22 0.22 0.21 0.23 7.7e-06 6.4e-06 9.9e-06 3.0e-06
14 PL gene expression ENSRNOG00000019270 0.18 0.08 4.3e-15 0.2 0.18 0.2 0.21 6.7e-15 6.2e-14 3.4e-15 1.2e-15

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail0.00.20.3-0.5-0.50.50.30.20.10.50.50.40.10.30.50.50.4
BMI without tail0.71.54.9-0.0-0.20.2-1.01.9-0.41.21.22.21.6-1.41.01.31.2
Body weight0.62.78.2-0.5-0.80.7-0.90.80.21.81.82.92.8-1.71.71.81.8
Epididymis fat weight1.22.94.7-1.6-1.71.70.8-0.11.32.12.12.11.70.22.12.22.1
Glucose0.20.20.70.40.5-0.50.20.7-0.5-0.4-0.4-0.6-0.80.2-0.4-0.5-0.4
Heart weight1.01.52.21.51.4-1.4-1.21.2-1.5-1.2-1.2-0.6-0.6-1.1-1.2-1.2-1.2
Left kidney weight0.51.54.30.60.4-0.5-2.01.8-0.90.60.61.91.6-2.10.50.60.6
Right kidney weight0.31.02.70.30.1-0.1-1.51.1-0.40.70.71.71.5-1.60.60.70.7
Tail length1.85.416.70.90.5-0.6-3.02.8-1.21.51.53.93.8-4.11.21.41.5
Length with tail1.24.416.00.1-0.30.2-2.11.1-0.21.81.83.74.0-3.21.71.81.9
Length without tail0.20.41.7-0.6-0.70.70.5-1.30.80.50.50.20.60.40.60.50.5
Liver weight, left1.72.84.5-1.6-1.71.70.3-0.91.51.91.92.12.1-0.12.02.01.9
Liver weight, right3.76.110.5-2.2-2.42.40.5-1.12.22.82.83.13.2-0.22.93.02.9
Parametrial fat weight1.12.13.9-1.4-1.41.40.90.81.22.02.01.40.70.81.81.81.9
Retroperitoneal fat weight5.618.429.1-3.9-4.24.21.6-0.93.65.45.45.14.80.45.25.35.3
Intraocular pressure0.91.34.60.91.0-1.0-0.21.5-1.0-1.0-1.0-1.4-2.10.5-1.1-1.1-1.0
Extensor digitorum longus weight0.31.32.7-0.9-1.01.0-0.00.60.71.51.51.61.3-0.11.41.41.5
Soleus weight1.03.07.3-1.2-1.41.3-0.40.31.02.12.12.72.5-0.82.02.12.1
Tibialis anterior weight0.10.41.7-0.1-0.20.2-0.60.00.10.50.51.11.3-0.90.50.60.5
Tibia length1.95.37.82.52.6-2.5-1.80.7-2.4-2.8-2.8-1.9-1.5-1.4-2.7-2.7-2.8
Number of licking bursts4.95.87.8-2.8-2.82.82.4-1.72.72.62.61.41.32.12.62.62.6
Food consumed during 24 hour testing period4.35.17.12.62.7-2.7-2.02.2-2.7-2.3-2.3-1.4-1.5-1.7-2.4-2.4-2.3
Times rat made contact with spout0.70.81.5-0.7-0.80.80.30.20.61.21.21.11.0-0.01.11.11.2
Mean time between licks in bursts2.43.313.41.71.4-1.4-3.21.7-1.7-0.4-0.42.02.4-3.7-0.4-0.2-0.3
Mean num. licks in bursts3.84.56.42.52.5-2.5-2.21.7-2.5-2.2-2.2-1.0-1.0-2.0-2.3-2.2-2.2
Std. dev. time between licks in bursts1.11.34.70.30.1-0.1-1.60.8-0.40.60.62.02.2-2.00.60.80.7
Water consumed over 24 hours0.30.41.2-0.7-0.60.61.1-0.60.70.40.4-0.3-0.31.00.40.30.4
Indifference point 0 sec2.94.66.82.52.5-2.5-2.41.9-2.6-2.2-2.2-0.8-0.7-2.2-2.3-2.1-2.1
Indifference point AUC0.40.51.5-0.3-0.40.4-0.60.40.10.80.81.21.2-0.70.70.90.7
Indifference point function ln k1.92.74.21.51.6-1.6-0.50.2-1.4-2.1-2.1-2.0-1.8-0.2-2.0-2.0-2.0
Indifference point function log k1.92.74.21.51.6-1.6-0.50.2-1.4-2.1-2.1-2.0-1.8-0.2-2.0-2.0-2.0
Delay discounting total patch changes 0 sec2.23.55.22.22.2-2.2-2.11.7-2.3-1.9-1.9-0.6-0.6-2.0-2.0-1.8-1.9
Delay discounting total patch changes 12 sec0.60.82.90.70.5-0.5-1.60.8-0.8-0.0-0.01.11.3-1.7-0.10.1-0.0
Delay discounting total patch changes 18 sec1.21.63.71.41.4-1.4-1.91.5-1.6-1.0-1.00.1-0.0-1.6-1.1-0.9-1.0
Delay discounting total patch changes 24 sec0.60.82.80.70.6-0.6-1.61.0-0.8-0.1-0.11.11.0-1.7-0.20.0-0.1
Delay discounting total patch changes 6 sec0.40.50.70.80.8-0.8-0.80.5-0.8-0.8-0.8-0.3-0.2-0.7-0.8-0.7-0.8
Delay discounting time to switch 0 sec2.53.76.6-2.4-2.32.32.6-2.32.41.61.60.10.12.51.71.51.6
Delay discounting water rate 0 sec2.33.75.32.32.3-2.3-2.21.7-2.3-2.0-2.0-0.7-0.6-2.1-2.0-1.9-1.9
Delay discounting water rate 12 sec2.23.34.32.12.1-2.1-1.71.5-2.0-2.0-2.0-1.1-1.2-1.4-2.0-1.9-2.0
Delay discounting water rate 18 sec1.11.53.11.51.4-1.5-1.71.7-1.4-0.8-0.80.20.1-1.8-0.9-0.8-0.8
Delay discounting water rate 24 sec1.52.13.51.41.5-1.5-0.70.4-1.2-1.9-1.9-1.5-1.4-0.4-1.8-1.7-1.8
Delay discounting water rate 6 sec1.31.92.51.61.6-1.6-1.21.1-1.4-1.5-1.5-1.0-1.0-1.0-1.5-1.5-1.5
Locomotor activity0.30.50.80.80.7-0.7-0.9-0.1-0.7-0.9-0.9-0.3-0.0-0.7-0.8-0.8-0.9
Locomotor testing distance1.11.84.21.61.5-1.5-2.11.1-1.6-1.1-1.10.10.4-1.9-1.1-1.1-1.1
Locomotor testing rearing0.40.62.30.40.3-0.3-1.30.6-0.50.30.31.21.5-1.50.20.30.3
Light reinforcement 12.03.66.4-2.3-2.22.22.5-1.62.31.81.80.40.12.31.81.81.8
Light reinforcement 20.30.41.7-0.2-0.10.11.00.30.1-0.1-0.1-0.9-1.31.2-0.2-0.2-0.2
Reaction time number correct0.60.82.00.50.6-0.50.2-0.9-0.1-1.2-1.2-1.4-1.10.4-1.0-1.1-1.1
Reaction time mean minus median0.30.41.40.60.6-0.6-0.90.5-0.7-0.3-0.30.50.6-1.2-0.3-0.3-0.3
Reaction time mean minus median AUC0.60.81.31.11.0-1.0-0.90.3-1.0-1.0-1.0-0.2-0.0-1.1-0.9-0.9-1.0
Reaction time num false alarms2.63.65.0-2.2-2.22.21.5-2.02.21.91.91.31.51.22.02.01.9
Reaction time num false alarms AUC1.31.92.9-1.7-1.71.71.1-1.71.71.21.20.70.91.11.41.41.3
Reaction time trials correct on left0.60.82.00.50.6-0.50.2-0.9-0.1-1.2-1.2-1.4-1.10.4-1.0-1.1-1.1
Reaction time trials on left0.60.82.00.40.5-0.50.2-0.9-0.1-1.2-1.2-1.4-1.10.5-1.0-1.1-1.1
Reaction time mean1.41.92.5-1.5-1.61.61.0-1.61.51.31.31.21.50.51.51.51.3
Reaction time mean AUC1.41.82.9-1.6-1.61.61.3-1.71.61.21.20.91.20.81.41.41.3
Median of all reaction times1.92.64.2-1.9-1.91.91.5-2.11.91.41.41.01.31.01.71.61.5
Reaction time omissions0.50.70.9-0.9-0.90.90.7-0.70.80.80.80.70.80.40.90.90.9
Reaction time false alarm rate1.92.73.7-1.9-1.91.91.0-1.21.71.81.81.41.40.91.91.91.8
Reaction time premature initiation rate1.11.44.30.70.5-0.5-1.91.9-0.90.50.51.81.6-2.10.30.50.5
Reaction time premature initiations0.60.92.61.00.9-0.9-1.61.3-1.0-0.3-0.30.70.6-1.6-0.4-0.3-0.3
Std. dev. reaction times0.50.72.7-0.3-0.40.4-0.50.10.20.80.81.61.6-1.00.90.90.8
Reaction time trials completed0.60.82.00.40.5-0.50.2-0.9-0.1-1.2-1.2-1.4-1.10.5-1.0-1.1-1.1
Reaction time trials AUC0.40.61.30.30.4-0.40.1-0.90.0-1.0-1.0-1.2-0.80.3-0.9-0.9-1.0
Social response proportion0.80.81.5-0.9-0.90.90.3-0.50.91.01.01.11.2-0.01.01.11.1
Social responses1.51.95.0-1.1-1.21.20.0-0.91.11.51.51.92.2-0.51.51.61.5
Social time1.72.25.0-1.8-1.71.72.2-2.21.91.01.0-0.20.22.01.11.01.0
Conditioned locomotion0.30.43.6-0.4-0.40.40.4-1.90.6-0.2-0.2-0.20.50.20.1-0.0-0.1
Cocaine response after cond. corrected2.12.43.3-1.7-1.71.71.3-0.81.61.81.81.21.01.01.81.81.8
Cocaine response after cond. not corrected0.40.50.7-0.8-0.80.80.70.10.70.80.80.40.00.70.80.80.8
Cocaine response before conditioning3.03.64.62.02.1-2.1-1.11.7-2.0-2.1-2.1-1.8-2.1-0.6-2.2-2.1-2.1
Saline control response1.21.54.71.51.3-1.3-2.01.2-1.4-0.7-0.70.60.8-2.2-0.8-0.7-0.7
Condit. Reinf. active minus inactive responses4.85.913.32.92.7-2.8-3.73.1-3.0-1.6-1.60.60.6-3.6-1.8-1.6-1.6
Condit. Reinf. active-inactive response ratio1.51.63.01.51.5-1.5-1.61.7-1.6-1.0-1.0-0.2-0.3-1.5-1.1-1.0-1.0
Condit. Reinf. active responses5.67.820.23.33.0-3.1-4.43.5-3.4-1.6-1.61.11.3-4.5-1.8-1.6-1.6
Condit. Reinf. inactive responses2.83.511.32.11.9-1.9-3.12.1-2.1-0.9-0.91.11.5-3.4-1.0-0.8-0.9
Condit. Reinf. lever presses12.417.131.95.14.8-4.9-5.64.7-5.2-3.3-3.3-0.1-0.1-5.4-3.6-3.3-3.3
Condit. Reinf. lever reinforcers received6.69.321.83.73.4-3.5-4.63.8-3.8-1.9-1.90.80.9-4.7-2.2-1.9-2.0
Pavlov. Cond. lever latency13.017.830.6-5.2-5.05.05.5-4.65.23.63.60.50.35.33.83.63.6
Pavlov. Cond. magazine entry latency4.04.56.52.52.5-2.5-2.22.1-2.6-2.1-2.1-1.0-1.1-1.9-2.2-2.1-2.1
Pavlov. Cond. change in total contacts11.015.323.34.84.7-4.7-4.84.1-4.8-3.5-3.5-0.9-0.7-4.6-3.7-3.5-3.5
Pavlov. Cond. index score10.613.822.04.54.4-4.4-4.74.0-4.6-3.3-3.3-0.7-0.6-4.4-3.5-3.2-3.3
Pavlov. Cond. latency score9.712.318.84.34.1-4.2-4.33.8-4.3-3.1-3.1-0.7-0.7-4.0-3.3-3.1-3.1
Pavlov. Cond. lever contacts13.618.932.25.35.1-5.1-5.74.8-5.4-3.7-3.7-0.5-0.4-5.4-3.9-3.7-3.7
Pavlov. Cond. magazine entry number6.88.412.2-3.5-3.43.43.1-2.83.52.82.81.31.32.73.02.92.9
Pavlov. Cond. intertrial magazine entries0.70.92.5-0.3-0.50.5-0.50.50.31.11.11.61.6-0.91.01.11.1
Pavlov. Cond. lever-magazine prob. diff.9.712.520.84.34.2-4.2-4.63.9-4.4-3.1-3.1-0.5-0.4-4.3-3.3-3.0-3.0
Pavlov. Cond. response bias14.219.631.85.45.2-5.3-5.64.8-5.5-3.9-3.9-0.8-0.6-5.3-4.1-3.9-3.9
Conditioned reinforcement - actives3.02.94.11.81.9-1.9-1.21.0-1.9-2.0-2.0-1.4-1.4-1.0-1.9-2.0-2.0
Conditioned reinforcement - inactives0.30.30.5-0.5-0.50.50.5-0.60.40.50.50.60.7-0.00.60.60.5
Conditioned locomotion3.54.26.02.22.2-2.2-1.41.2-2.1-2.4-2.4-1.8-1.7-0.9-2.4-2.5-2.4
Intermittent access intake day 1-15 change0.80.81.81.11.1-1.1-0.71.3-1.2-0.7-0.7-0.5-0.7-0.6-0.9-0.8-0.7
Intermittent access intake escalation1.00.91.91.11.1-1.1-0.81.4-1.2-0.8-0.8-0.6-0.8-0.6-0.9-0.9-0.8
Intermittent access intake escalation 20.10.10.80.20.1-0.2-0.50.9-0.20.20.20.50.3-0.50.20.20.2
Intermitt. access day 1 inactive lever presses0.50.50.8-0.8-0.80.80.6-0.60.80.80.80.70.70.20.90.80.8
Intermitt. access day 15 inactive lever presses0.40.40.70.60.6-0.6-0.3-0.2-0.6-0.8-0.8-0.8-0.4-0.2-0.8-0.8-0.8
Intermitt. access escalation Index0.20.20.40.40.4-0.4-0.60.2-0.4-0.4-0.4-0.00.0-0.5-0.4-0.4-0.4
Intermittent access day 1 total infusions1.11.32.61.31.3-1.3-1.60.9-1.4-1.1-1.1-0.2-0.0-1.4-1.1-1.0-1.1
Intermittent access day 15 total infusions1.82.02.91.71.6-1.6-1.51.1-1.7-1.4-1.4-0.7-0.5-1.3-1.5-1.4-1.5
Intermittent access terminal intake (last 3 days)1.31.42.51.41.4-1.4-1.61.0-1.5-1.1-1.1-0.3-0.1-1.4-1.1-1.1-1.1
Intermittent access total infusions1.11.22.01.31.3-1.3-1.41.0-1.4-1.0-1.0-0.2-0.1-1.3-1.0-1.0-1.0
Intermittent access day 1 locomotion0.30.30.60.60.6-0.6-0.30.0-0.6-0.7-0.7-0.7-0.4-0.1-0.7-0.8-0.8
Intermittent access day 15 total locomotion1.71.92.71.51.6-1.6-1.11.4-1.7-1.4-1.4-1.0-1.1-0.7-1.5-1.5-1.4
Intermittent access total locomotion0.80.91.41.11.1-1.1-0.90.7-1.2-1.0-1.0-0.5-0.3-0.8-1.0-1.0-1.0
Intermittent access standard deviation0.00.00.30.10.1-0.1-0.20.5-0.20.20.20.30.1-0.20.10.10.1
Cocaine induced anxiety2.22.54.5-1.9-1.91.91.9-2.12.01.31.30.30.51.71.41.31.3
Post-drug Anxiety1.31.42.0-1.3-1.31.30.6-1.21.41.31.31.01.20.51.31.31.3
Baseline Anxiety1.11.13.11.31.2-1.2-1.81.6-1.1-0.5-0.50.40.3-1.6-0.7-0.6-0.5
Lifetime Intake1.51.72.61.61.5-1.5-1.61.2-1.6-1.2-1.2-0.3-0.2-1.5-1.2-1.2-1.2
Incentive Sensitization - Responses1.11.13.01.21.1-1.1-1.71.3-1.3-0.6-0.60.40.6-1.7-0.6-0.5-0.6
Incentive Sensitization - Breakpoint1.01.02.51.21.2-1.2-1.61.2-1.3-0.7-0.70.20.4-1.6-0.7-0.7-0.7
Progressive ratio test 1 active lever presses0.00.00.0-0.0-0.00.00.2-0.0-0.00.10.1-0.1-0.00.10.00.00.0
Progressive ratio test 1 breakpoint0.00.00.1-0.0-0.10.10.10.2-0.00.20.20.10.1-0.00.10.10.2
Progressive ratio test 1 inactive lever presses0.40.40.70.80.7-0.8-0.60.6-0.8-0.6-0.6-0.2-0.2-0.7-0.5-0.6-0.6
Progressive ratio test 2 active lever presses0.50.61.30.90.9-0.9-1.11.0-1.0-0.5-0.50.10.2-1.1-0.5-0.5-0.5
Progressive ratio test 2 breakpoint0.50.61.50.90.9-0.9-1.21.0-1.0-0.5-0.50.20.3-1.2-0.5-0.5-0.5
Progressive ratio test 2 inactive lever presses1.01.11.71.21.2-1.2-0.70.4-1.2-1.3-1.3-0.8-0.5-0.8-1.2-1.2-1.3
Total sessions with >9 infusions3.74.15.92.42.4-2.4-1.92.0-2.4-2.0-2.0-1.2-1.3-1.5-2.1-2.1-2.0
Short access day 1 total inactive lever presses0.00.00.20.00.0-0.00.4-0.50.1-0.1-0.1-0.20.00.1-0.0-0.1-0.1
Short access day 10 total inactive lever presses0.10.10.3-0.4-0.40.40.5-0.60.50.10.1-0.1-0.20.50.30.20.1
Short access day 1 total infusions2.02.13.51.81.7-1.7-1.91.5-1.8-1.3-1.3-0.2-0.1-1.9-1.3-1.2-1.3
Short access day 10 total infusions1.21.33.11.41.3-1.3-1.81.6-1.5-0.7-0.70.20.2-1.6-0.8-0.8-0.7
Short access total infusions1.11.32.31.41.3-1.3-1.51.3-1.4-0.9-0.9-0.00.0-1.5-0.9-0.9-0.9
Short access day 1 locomotion3.23.34.51.92.0-2.0-0.81.5-1.9-2.1-2.1-1.7-2.0-0.5-2.1-2.1-2.1
Short access day 10 total locomotion0.10.10.30.40.3-0.3-0.50.6-0.4-0.1-0.10.20.4-0.6-0.2-0.1-0.1
Short access total locomotion0.20.20.50.60.6-0.6-0.20.7-0.6-0.4-0.4-0.4-0.3-0.2-0.5-0.5-0.5
Compulsive drug intake0.40.42.0-0.00.1-0.10.4-0.2-0.0-0.5-0.5-1.0-1.40.9-0.4-0.5-0.5
One hour access (0.3 mA shock)1.61.83.81.61.5-1.5-1.91.4-1.6-1.2-1.2-0.1-0.2-1.6-1.2-1.1-1.2
One hour access (shock baseline)1.11.23.31.31.2-1.2-1.71.1-1.3-0.8-0.80.30.6-1.8-0.8-0.8-0.8
Number of responses in last shaping day0.10.10.50.20.1-0.1-0.60.3-0.20.10.10.60.7-0.70.10.10.1
Context. condit. distance diff. score2.63.24.32.12.1-2.1-1.41.1-2.0-2.0-2.0-1.2-1.1-1.4-2.0-2.0-2.0
Locomotion velocity, session 10.30.41.7-0.00.1-0.10.6-0.10.1-0.4-0.4-1.1-1.31.0-0.4-0.5-0.4
Locomotion distance, session 11.21.51.91.31.4-1.4-0.91.0-1.3-1.3-1.3-1.1-1.2-0.5-1.4-1.4-1.3
Locomotion velocity, session 20.10.10.60.40.4-0.4-0.40.8-0.4-0.1-0.1-0.0-0.2-0.2-0.2-0.2-0.1
Locomotion distance, session 20.40.60.70.80.8-0.8-0.80.4-0.8-0.9-0.9-0.5-0.4-0.5-0.8-0.9-0.9
Locomotion velocity, session 31.01.11.71.11.1-1.1-0.60.2-0.9-1.3-1.3-1.1-0.9-0.4-1.3-1.3-1.3
Locomotion distance, session 32.12.23.21.51.6-1.6-0.70.9-1.5-1.7-1.7-1.6-1.6-0.4-1.8-1.8-1.7
Stereotopy head waving bouts, day 30.70.81.8-0.8-0.90.90.1-0.70.91.01.01.01.3-0.01.01.01.0
Stereotopy head waving duration, day 30.10.10.20.40.4-0.4-0.4-0.0-0.3-0.5-0.5-0.4-0.3-0.1-0.5-0.5-0.5
Locomotion velocity, session 70.10.10.5-0.3-0.30.30.6-0.50.40.10.1-0.4-0.50.70.10.00.0
Locomotion distance, session 70.20.30.5-0.6-0.60.60.4-0.70.60.40.40.30.40.30.50.50.5
Stereotopy head waving bouts, day 73.13.64.82.22.2-2.2-1.81.8-2.2-1.9-1.9-1.2-1.2-1.3-2.1-2.0-1.9
Stereotopy head waving duration, day 73.44.15.92.42.4-2.4-2.12.4-2.4-1.9-1.9-1.0-1.2-1.6-2.1-2.0-1.9
Locomotion velocity, session 80.80.91.41.21.2-1.2-0.90.6-1.0-1.0-1.0-0.5-0.4-0.9-1.0-1.0-1.0
Locomotion distance, session 82.23.24.62.12.1-2.1-1.71.2-2.1-1.9-1.9-1.0-0.7-1.7-1.9-2.0-1.9
Degree of sensitization distance2.82.86.2-1.4-1.51.50.2-1.01.41.91.92.22.5-0.41.92.01.9
Degree of sensitization stereotypy6.47.09.63.13.1-3.1-2.52.5-3.1-2.7-2.7-1.6-1.6-2.0-2.9-2.8-2.7
Condit. Reinf. active minus inactive responses0.20.31.00.10.0-0.0-0.60.2-0.10.30.30.91.0-0.90.30.40.3
Condit. Reinf. active-inactive response ratio0.40.41.60.40.3-0.3-0.90.7-0.40.20.20.91.0-1.20.10.20.2
Condit. Reinf. active responses0.20.20.9-0.2-0.30.3-0.3-0.40.20.30.30.71.0-0.50.40.40.3
Condit. Reinf. inactive responses0.10.10.7-0.3-0.30.30.3-0.90.4-0.0-0.0-0.10.20.30.10.10.0
Incentive salience index mean0.20.20.80.20.1-0.1-0.60.3-0.20.10.10.70.8-0.90.20.20.1
Condit. Reinf. lever presses0.10.10.40.30.3-0.3-0.30.7-0.3-0.1-0.10.10.0-0.4-0.1-0.1-0.1
Time in familiar zone, hab. session 10.10.10.3-0.1-0.10.1-0.10.20.00.40.40.50.5-0.30.30.40.4
Time in novel zone, hab. session 10.30.20.4-0.6-0.60.60.5-0.50.70.50.50.20.20.50.50.50.5
Total zone transitions, hab. session 10.40.51.20.60.6-0.60.20.2-0.5-0.7-0.7-1.1-1.10.4-0.8-0.9-0.8
Total locomotion distance, hab. session 11.72.54.4-1.4-1.61.60.5-0.91.41.81.82.02.1-0.11.81.81.8
Locomotion velocity, hab. session 11.11.63.3-1.1-1.21.20.3-0.91.11.41.41.61.8-0.21.41.41.4
Time in familiar zone, hab. session 20.90.92.51.11.0-1.0-1.60.7-1.0-0.7-0.70.30.4-1.6-0.7-0.6-0.7
Time in novel zone, hab. session 20.20.21.0-0.4-0.40.40.9-0.20.40.10.1-0.5-0.71.00.10.10.1
Total zone transitions, hab. session 21.92.43.31.81.8-1.8-1.11.0-1.7-1.7-1.7-1.3-1.1-0.9-1.8-1.8-1.8
Total locomotion distance, hab. session 21.01.35.3-0.6-0.70.7-0.4-0.70.61.01.01.82.3-1.11.11.11.1
Locomotion velocity, hab. session 21.31.76.5-0.7-0.90.9-0.3-0.80.71.31.32.02.5-1.11.31.41.3
Novel to familiar place preference ratio0.20.21.70.0-0.00.0-0.1-1.30.1-0.3-0.30.10.8-0.5-0.1-0.2-0.3
Novelty place preference0.20.21.80.0-0.00.0-0.1-1.30.1-0.3-0.30.10.8-0.5-0.1-0.2-0.3
Time in novel zone, NPP test0.30.31.70.20.2-0.2-0.3-1.3-0.1-0.5-0.50.00.8-0.7-0.3-0.3-0.5
Total zone transitions, NPP test0.60.81.30.90.9-0.9-0.30.8-0.9-0.9-0.9-1.0-1.1-0.0-1.0-1.1-1.0
Total locomotion distance, NPP test1.11.63.0-1.1-1.21.20.3-0.61.01.41.41.61.7-0.21.51.51.5
Locomotion velocity, NPP test1.42.02.9-1.4-1.51.50.6-0.71.31.71.71.71.70.21.71.71.7
Pavlov. Cond. lever latency0.91.12.2-1.3-1.21.21.5-1.21.30.90.90.00.01.30.90.80.9
Pavlov. Cond. magazine entry latency2.12.75.42.01.9-1.9-2.31.8-2.0-1.3-1.30.10.1-2.2-1.4-1.3-1.3
Pavlov. Cond. change in total contacts1.11.12.41.31.2-1.2-1.51.3-1.3-0.8-0.80.10.1-1.5-0.8-0.8-0.8
Pavlov. Cond. index score2.12.75.32.01.9-1.9-2.32.2-2.0-1.2-1.20.10.0-2.2-1.3-1.2-1.2
Pavlov. Cond. latency score2.02.65.21.91.8-1.9-2.32.0-2.0-1.2-1.20.10.0-2.1-1.3-1.2-1.2
Pavlov. Cond. lever contacts0.91.02.61.21.1-1.1-1.51.6-1.2-0.6-0.60.30.1-1.4-0.7-0.6-0.6
Pavlov. Cond. magazine entry number2.83.55.9-2.3-2.22.22.4-2.32.31.51.50.30.42.21.71.61.6
Pavlov. Cond. intertrial magazine entries0.70.81.7-1.0-1.01.01.3-1.21.10.70.7-0.00.11.10.80.60.7
Pavlov. Cond. lever-magazine prob. diff.1.82.24.31.81.7-1.8-2.12.1-1.9-1.1-1.10.0-0.1-1.9-1.2-1.1-1.1
Pavlov. Cond. response bias0.81.02.31.21.1-1.1-1.51.4-1.2-0.6-0.60.20.1-1.4-0.7-0.6-0.6
Bone: apparent density0.10.20.70.10.1-0.10.40.0-0.1-0.3-0.3-0.7-0.80.6-0.3-0.3-0.3
Bone surface0.61.11.71.31.2-1.2-1.31.3-1.3-0.9-0.9-0.2-0.3-1.1-1.0-0.9-0.9
Bone volume0.30.60.90.90.9-0.9-1.00.7-0.9-0.7-0.7-0.2-0.1-0.9-0.7-0.7-0.7
Bone: connectivity density0.50.83.30.60.7-0.70.11.1-0.7-0.7-0.7-1.3-1.80.7-0.9-0.9-0.8
Bone: cortical apparent density2.63.44.4-2.0-2.12.11.5-1.72.01.91.91.51.70.92.02.11.9
Bone: cortical area0.20.31.40.40.3-0.3-0.90.2-0.4-0.0-0.00.71.0-1.2-0.00.1-0.0
Bone: cortical porosity1.41.52.31.21.3-1.3-0.70.4-1.2-1.5-1.5-1.3-1.2-0.3-1.4-1.5-1.5
Bone: cortical porosity1.21.32.01.11.2-1.2-0.60.2-1.0-1.4-1.4-1.2-1.1-0.3-1.3-1.4-1.4
Bone: cortical thickness0.10.20.6-0.5-0.40.50.5-0.80.50.30.30.00.20.40.30.30.3
Bone: cortical thickness0.20.20.40.30.3-0.3-0.3-0.5-0.2-0.6-0.6-0.4-0.0-0.2-0.5-0.5-0.6
Bone: cortical tissue density2.63.34.3-2.0-2.12.11.5-1.82.01.81.81.41.60.92.02.01.9
Bone: elastic displacement1.11.34.1-1.3-1.21.21.9-1.11.30.60.6-0.7-0.82.00.70.60.6
Bone: elastic work1.01.35.5-1.1-0.91.01.9-0.71.10.40.4-1.1-1.52.30.40.30.3
Bone: endosteal estimation0.71.54.91.21.0-1.0-2.11.9-1.3-0.1-0.11.31.2-2.2-0.3-0.0-0.1
Bone: endosteal perimeter0.91.95.91.51.4-1.4-2.32.0-1.6-0.4-0.41.01.0-2.4-0.6-0.4-0.4
Bone: final force0.20.31.6-0.4-0.50.50.1-1.30.60.20.20.40.9-0.20.40.40.2
Bone: final moment0.10.20.9-0.2-0.20.2-0.2-1.00.30.00.00.40.9-0.40.20.20.1
Bone: marrow area0.61.24.11.00.8-0.8-1.91.7-1.10.00.01.31.2-2.0-0.10.10.1
Bone: maximum diameter1.01.85.41.61.4-1.4-2.11.6-1.6-0.7-0.70.70.9-2.3-0.8-0.6-0.7
Bone: maximum force0.00.10.3-0.0-0.10.1-0.2-0.50.1-0.0-0.00.30.6-0.40.10.10.0
Bone: maximum moment0.10.10.30.30.2-0.2-0.5-0.1-0.2-0.2-0.20.20.5-0.6-0.1-0.1-0.2
Bone: minimum diameter0.81.45.30.0-0.20.2-1.20.7-0.11.01.02.12.3-1.80.91.11.0
Bone: periosteal estimation0.61.24.21.10.9-0.9-1.91.5-1.2-0.2-0.21.11.1-2.1-0.3-0.1-0.2
Bone: periosteal perimeter0.71.23.81.21.1-1.1-1.81.4-1.2-0.4-0.40.80.9-2.0-0.5-0.4-0.4
Bone: post-yield work0.10.10.30.40.4-0.4-0.50.1-0.4-0.4-0.4-0.10.0-0.5-0.4-0.3-0.4
Bone: stiffness0.81.23.2-1.0-1.11.10.2-1.31.11.01.01.31.8-0.21.21.21.1
Bone: tissue strength0.90.83.00.20.3-0.30.7-0.3-0.1-0.8-0.8-1.6-1.71.2-0.8-0.9-0.9
Bone: trabecular number0.40.62.5-0.7-0.60.61.4-0.60.70.20.2-0.9-1.01.60.20.10.2
Bone: trabecular spacing0.81.01.61.21.2-1.2-0.91.2-1.3-1.0-1.0-0.5-0.6-0.8-1.0-1.0-1.0
Bone: trabecular thickness0.50.61.8-0.8-0.80.80.3-1.30.90.60.60.61.10.10.80.80.7
Bone: trabecular tissue density3.34.79.2-2.0-2.22.20.7-1.82.12.32.32.53.0-0.12.42.52.3
Breakpoint value in progressive ratio session0.20.20.6-0.2-0.20.20.3-0.80.3-0.2-0.2-0.7-0.50.8-0.2-0.2-0.2
Distance traveled before self-admin1.51.62.3-1.5-1.51.51.3-1.11.41.31.30.60.61.21.31.41.3
Distance traveled after self-admin0.40.51.4-0.00.1-0.10.7-1.10.2-0.7-0.7-1.2-0.80.8-0.6-0.6-0.6
Delta time in closed arm before/after self-admin4.44.36.9-2.0-2.12.10.3-0.71.82.52.52.52.40.22.52.62.5
Delta time in open arm before/after self-admin3.23.14.62.12.1-2.1-2.01.8-2.1-1.6-1.6-0.5-0.5-1.9-1.7-1.7-1.6
Diff in mean of infusions in LGA sessions2.73.04.4-1.9-2.02.01.4-1.42.12.02.01.01.21.31.91.82.0
Extinction: sum of active levers before priming0.10.10.2-0.3-0.30.30.2-0.10.30.30.30.20.10.20.40.30.4
Active lever presses in extinction session 64.03.95.91.92.0-2.0-0.90.4-1.8-2.4-2.4-2.3-2.0-0.3-2.4-2.4-2.4
Delta distance traveled before/after self-admin2.22.33.51.71.7-1.7-1.30.2-1.5-1.9-1.9-1.2-0.7-1.2-1.8-1.8-1.8
Delta ambulatory time before/after self-admin2.62.94.51.81.8-1.8-1.00.2-1.5-2.1-2.1-1.6-1.2-1.0-2.0-2.1-2.1
Time in closed arm before self-admin4.04.67.42.12.2-2.1-0.90.0-1.8-2.7-2.7-2.4-1.9-0.5-2.7-2.7-2.7
Time in closed arm after self-admin0.50.52.8-0.8-0.70.70.8-1.70.9-0.0-0.0-0.7-0.41.20.10.1-0.1
Time in open arm before self-admin5.15.47.6-2.7-2.72.72.4-1.32.52.52.51.30.82.22.62.52.6
Time in open arm after self-admin0.40.41.4-0.0-0.10.1-0.31.1-0.20.70.71.20.8-0.70.60.60.7
Sum of active levers in priming session hrs 5-60.10.11.0-0.2-0.20.20.3-1.00.4-0.1-0.1-0.40.10.4-0.1-0.1-0.1
Time to tail flick, vehicle, before self-admin0.00.00.20.10.1-0.1-0.1-0.4-0.0-0.2-0.2-0.30.10.0-0.2-0.2-0.1
Time to tail flick, vehicle, after self-admin3.63.85.32.22.3-2.3-1.51.7-2.3-2.1-2.1-1.4-1.4-1.3-2.2-2.2-2.1
Time to tail flick, test, before self-admin0.40.41.40.70.6-0.6-1.11.2-0.70.10.10.50.5-1.0-0.1-0.20.0
Time to tail flick, test, after self-admin0.80.82.50.20.1-0.1-1.50.7-0.20.60.61.51.6-1.40.50.60.7
Delta time to tail flick, vehicle, before/after SA2.42.43.41.71.7-1.8-1.11.8-1.8-1.6-1.6-1.0-1.5-0.9-1.6-1.6-1.6
Delta time to tail flick, test, before/after SA0.30.30.5-0.6-0.60.60.1-0.50.60.60.60.50.50.20.60.70.6
Ambulatory time before self-admin1.21.32.0-1.4-1.41.41.3-1.11.31.01.00.20.31.41.01.11.0
Ambulatory time after self-admin0.91.02.80.40.5-0.40.6-1.3-0.1-1.2-1.2-1.7-1.10.7-1.1-1.1-1.2
Total heroin consumption0.40.50.80.70.7-0.7-0.7-0.4-0.6-0.9-0.9-0.6-0.1-0.5-0.8-0.9-0.9
Area under the delay curve0.20.20.2-0.5-0.50.50.2-0.20.40.50.50.40.30.20.50.50.4
Delay disc. indifference point, 0s delay0.40.41.10.80.7-0.7-1.10.6-0.7-0.5-0.50.20.4-1.1-0.5-0.4-0.5
Delay disc. indifference point, 16s delay0.20.21.2-0.4-0.40.40.5-1.10.5-0.0-0.0-0.10.10.40.10.10.0
Delay disc. indifference point, 2s delay0.30.41.30.50.4-0.4-0.91.0-0.60.10.10.80.7-1.10.00.10.1
Delay disc. indifference point, 24s delay1.21.23.6-1.3-1.31.31.3-1.91.40.70.70.20.51.10.90.80.7
Delay disc. indifference point, 4s delay0.50.61.80.40.2-0.2-1.30.7-0.40.30.31.21.2-1.30.30.30.4
Delay disc. indifference point, 8s delay0.00.00.0-0.1-0.10.1-0.0-0.00.10.10.10.0-0.00.10.10.10.1
Delay discount exponential model param0.20.20.30.50.5-0.5-0.20.2-0.4-0.5-0.5-0.4-0.3-0.3-0.5-0.5-0.5
Delay discount hyperbolic model param0.10.20.30.40.4-0.40.1-0.1-0.3-0.5-0.5-0.6-0.40.0-0.5-0.5-0.5
Fecal boli incidents, locomotor time 11.11.22.00.91.0-1.0-0.60.5-0.8-1.4-1.4-1.2-1.4-0.0-1.2-1.3-1.4
Change in fecal boli incidents, locomotor task0.90.91.2-1.0-1.01.00.8-0.81.01.11.10.60.60.61.01.11.0
Time >=10cm from walls, locomotor time 11.71.72.81.41.4-1.4-1.00.3-1.3-1.7-1.7-1.0-0.8-0.9-1.5-1.5-1.7
Bouts of movement, locomotor time 10.20.20.40.40.4-0.4-0.4-0.1-0.4-0.6-0.6-0.3-0.1-0.3-0.6-0.5-0.5
Total resting periods, locomotor time 10.30.40.80.40.4-0.4-0.1-0.3-0.4-0.9-0.9-0.8-0.60.1-0.8-0.8-0.8
Rest time, locomotor task time 10.20.20.60.10.2-0.20.1-0.70.0-0.5-0.5-0.8-0.50.3-0.5-0.5-0.5
Distance moved, locomotor task time 10.40.51.3-0.2-0.20.2-0.30.9-0.10.80.81.10.9-0.60.80.80.8
Vertical activity count, locomotor time 10.20.20.70.10.1-0.1-0.40.4-0.20.30.30.80.8-0.80.30.40.3
Time >=10cm from walls, locomotor time 21.01.02.91.21.1-1.1-1.50.1-1.0-1.0-1.00.10.6-1.7-0.8-0.8-0.9
Bouts of movement, locomotor time 20.60.73.2-0.3-0.40.4-0.6-0.30.20.60.61.51.8-1.00.60.80.6
Total resting periods, locomotor time 20.70.72.6-0.6-0.70.7-0.2-0.50.50.80.81.41.6-0.60.80.90.8
Rest time, locomotor task time 22.02.44.1-1.9-1.81.82.0-1.91.91.31.30.00.12.01.31.31.3
Distance moved, locomotor task time 21.92.35.31.81.7-1.7-2.31.7-1.9-1.0-1.00.30.3-2.3-1.1-1.0-1.0
Vertical activity count, locomotor time 20.50.62.40.70.6-0.6-1.20.6-0.7-0.2-0.20.80.9-1.6-0.1-0.1-0.2
Weight adjusted by age0.40.41.10.30.2-0.2-1.11.0-0.50.40.41.00.8-1.00.30.40.4
Seeking ratio, delayed vs. immediate footshock0.50.62.5-0.8-0.70.71.3-0.50.80.40.4-0.7-1.11.60.40.20.4
Locomotion in novel chamber1.01.22.40.70.9-0.8-0.10.1-0.7-1.4-1.4-1.5-1.50.4-1.3-1.3-1.4
Locomotion in novel chamber post-restriction3.13.64.62.12.1-2.1-1.41.9-2.1-2.1-2.1-1.5-1.6-0.9-2.2-2.0-2.1
Progressive ratio0.20.30.90.40.4-0.40.20.4-0.4-0.5-0.5-0.8-0.90.3-0.6-0.6-0.5
Food seeking constrained by brief footshock0.50.62.30.70.5-0.6-1.21.0-0.70.10.11.01.1-1.5-0.00.10.1
Seeking ratio, punishment vs. effort0.60.82.80.20.1-0.1-1.20.7-0.20.50.51.51.7-1.50.50.60.6
Run reversals in cocaine runway, females3.23.27.6-1.0-1.21.2-0.40.91.02.22.22.82.5-0.92.02.22.2
Run reversals in cocaine runway, males0.10.00.3-0.1-0.10.10.20.00.1-0.0-0.0-0.3-0.50.50.0-0.1-0.1
Latency to leave start box in cocaine runway2.42.64.3-1.7-1.81.81.3-0.31.52.12.11.30.91.11.91.92.0
Latency to leave start box in cocaine runway, F2.83.05.2-1.7-1.81.80.9-0.11.52.32.31.81.50.62.12.22.3
Latency to leave start box in cocaine runway, M0.20.20.9-0.3-0.20.20.8-0.10.3-0.0-0.0-0.6-0.91.0-0.0-0.1-0.0
Cd content in liver0.70.81.3-0.9-0.90.90.50.40.61.11.11.00.60.41.11.21.1
Co content in liver0.81.03.71.00.9-0.9-1.71.0-1.0-0.3-0.30.91.1-1.9-0.3-0.2-0.3
Cu content in liver0.50.62.20.60.5-0.5-1.31.2-0.70.10.11.01.0-1.50.10.20.1
Fe content in liver0.10.10.1-0.2-0.20.20.0-0.10.20.30.30.30.4-0.10.30.30.3
K content in liver0.50.50.9-0.7-0.70.70.2-0.50.70.80.80.81.00.00.90.80.9
Mg content in liver0.10.10.20.30.3-0.3-0.40.4-0.3-0.1-0.10.10.2-0.5-0.1-0.1-0.1
Mn content in liver0.91.03.4-0.9-0.80.81.7-1.41.10.20.2-1.0-1.01.80.30.10.1
Na content in liver0.50.50.80.90.9-0.9-0.50.9-0.8-0.6-0.6-0.5-0.6-0.4-0.7-0.7-0.6
Rb content in liver0.60.81.81.11.0-1.0-1.31.4-1.1-0.5-0.50.0-0.1-1.1-0.6-0.6-0.6
Se content in liver2.32.75.6-2.0-1.91.92.4-1.72.01.41.4-0.1-0.22.31.51.31.4
Sr content in liver0.40.31.20.40.5-0.40.20.5-0.4-0.5-0.5-0.9-1.10.4-0.6-0.6-0.6
Zn content in liver3.84.26.72.42.4-2.4-2.52.6-2.6-1.7-1.7-0.5-0.7-2.2-1.9-1.7-1.7