Hub : Genes

Tmem223

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000019266 0.16 0.08 5.6e-10 0.16 0.17 0.18 0.18 5.2e-09 1.3e-09 3.4e-10 4.5e-10
2 Brain gene expression ENSRNOG00000019266 0.15 0.07 1.7e-15 0.18 0.17 0.15 0.16 4.4e-16 2.0e-15 1.4e-13 4.6e-15
3 Brain mRNA stability ENSRNOG00000019266 0.12 0.06 6.3e-12 0.13 0.13 0.12 0.13 5.1e-12 7.8e-12 2.0e-11 8.3e-12
4 Liver gene expression ENSRNOG00000019266 0.08 0.06 3.3e-04 0.02 0.02 0.01 0.01 1.0e-03 3.7e-03 7.6e-03 9.0e-03
5 Liver mRNA stability ENSRNOG00000019266 0.08 0.05 2.3e-03 0.01 0.01 0 0.01 2.5e-02 2.8e-02 7.6e-02 3.5e-02
6 NAcc gene expression ENSRNOG00000019266 0.08 0.05 2.5e-06 0.07 0.06 0.06 0.07 5.3e-06 2.3e-05 4.8e-05 1.2e-05
7 NAcc mRNA stability ENSRNOG00000019266 0.05 0.04 1.1e-04 0.04 0.02 0.02 0.03 1.1e-03 7.3e-03 9.8e-03 2.2e-03
8 OFC gene expression ENSRNOG00000019266 0.22 0.14 4.1e-04 0.01 0.01 0.03 0.03 1.4e-01 1.4e-01 7.2e-02 6.4e-02
9 OFC mRNA stability ENSRNOG00000019266 0.25 0.13 6.0e-05 0.12 0.06 0.03 0.1 1.1e-03 1.9e-02 6.9e-02 2.2e-03
10 PL gene expression ENSRNOG00000019266 0.1 0.05 4.9e-09 0.14 0.12 0.12 0.13 1.9e-10 2.1e-09 4.3e-09 3.5e-10
11 PL mRNA stability ENSRNOG00000019266 0.05 0.03 2.0e-04 0.06 0.04 0.04 0.06 2.1e-05 3.2e-04 2.2e-04 3.5e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail2.78.717.52.62.52.64.04.22.72.72.42.82.52.7
BMI without tail1.12.33.51.51.31.51.41.91.51.71.21.81.21.5
Body weight3.514.717.64.23.84.02.83.04.24.23.74.23.84.2
Epididymis fat weight0.40.82.1-0.7-1.0-1.11.21.5-0.5-0.5-0.6-0.9-0.9-0.5
Glucose2.33.65.0-2.1-2.2-2.20.60.6-2.0-2.0-1.9-2.0-2.1-2.0
Heart weight0.71.02.0-1.1-1.2-0.90.10.8-1.2-0.8-1.4-0.6-1.1-1.2
Left kidney weight0.10.21.00.30.10.01.01.00.3-0.00.40.30.20.4
Right kidney weight0.20.61.90.60.60.41.41.00.6-0.10.90.50.60.7
Tail length0.92.73.81.91.71.8-1.0-0.61.92.01.42.01.51.8
Length with tail2.17.810.63.32.93.10.60.73.23.12.83.02.93.2
Length without tail1.84.05.22.32.02.21.20.92.22.12.01.92.22.3
Liver weight, left0.30.51.0-0.7-0.7-0.6-0.5-0.5-0.8-0.5-1.0-0.8-0.8-0.7
Liver weight, right0.10.20.90.1-0.00.10.80.9-0.00.3-0.6-0.1-0.00.1
Parametrial fat weight1.32.53.5-1.8-1.7-1.71.00.9-1.6-1.9-1.5-1.8-1.6-1.8
Retroperitoneal fat weight1.96.49.0-2.9-3.0-2.70.60.9-2.8-2.5-2.7-2.5-3.0-2.8
Intraocular pressure0.20.20.9-0.3-0.3-0.5-0.8-1.0-0.2-0.40.4-0.4-0.3-0.1
Extensor digitorum longus weight6.124.430.65.55.25.32.92.95.45.25.15.15.25.5
Soleus weight2.36.89.1-2.8-3.0-2.6-0.8-0.5-3.0-2.6-3.0-2.9-3.0-2.9
Tibialis anterior weight8.930.838.76.26.06.12.31.96.25.56.16.26.06.2
Tibia length1.43.89.11.92.01.52.00.82.21.23.01.82.02.1
Number of licking bursts0.00.00.10.1-0.20.20.20.2-0.00.00.10.0-0.00.1
Food consumed during 24 hour testing period0.10.10.5-0.3-0.2-0.50.1-0.4-0.2-0.4-0.0-0.7-0.2-0.1
Times rat made contact with spout0.20.20.60.40.30.7-0.8-0.50.30.70.10.50.30.3
Mean time between licks in bursts0.70.93.50.90.91.0-0.50.70.81.90.11.20.90.8
Mean num. licks in bursts0.10.10.7-0.2-0.0-0.1-0.8-0.7-0.20.1-0.4-0.1-0.1-0.2
Std. dev. time between licks in bursts0.20.31.0-0.4-0.3-0.2-0.90.1-0.50.5-1.0-0.3-0.3-0.4
Water consumed over 24 hours0.40.50.90.90.70.9-0.4-0.30.80.90.60.60.70.9
Indifference point 0 sec0.50.81.30.90.81.10.60.50.90.90.90.90.80.9
Indifference point AUC1.82.24.41.71.71.20.7-0.11.80.92.11.21.81.8
Indifference point function ln k3.04.39.7-2.3-2.4-1.5-0.80.6-2.5-1.2-3.1-1.9-2.3-2.6
Indifference point function log k3.04.39.7-2.3-2.4-1.5-0.80.6-2.5-1.2-3.1-1.9-2.3-2.6
Delay discounting total patch changes 0 sec0.50.71.50.90.81.20.20.20.91.10.71.00.80.9
Delay discounting total patch changes 12 sec5.37.19.63.02.93.00.80.23.02.43.03.03.12.9
Delay discounting total patch changes 18 sec0.40.61.00.80.70.80.1-0.60.80.41.00.70.90.8
Delay discounting total patch changes 24 sec6.68.311.33.23.13.41.71.43.12.83.03.13.23.1
Delay discounting total patch changes 6 sec1.01.52.31.31.21.50.90.81.21.31.01.31.41.3
Delay discounting time to switch 0 sec0.50.83.20.60.80.41.81.20.60.21.00.70.90.7
Delay discounting water rate 0 sec0.40.71.2-0.7-0.7-0.5-1.1-0.8-0.8-0.4-1.0-1.0-0.9-0.9
Delay discounting water rate 12 sec1.52.35.2-1.5-1.8-1.0-1.7-0.6-1.5-0.6-2.3-1.5-1.8-1.7
Delay discounting water rate 18 sec0.60.72.5-0.8-0.9-0.2-0.50.6-1.00.1-1.6-0.7-1.0-1.1
Delay discounting water rate 24 sec1.11.63.0-1.3-1.4-0.9-1.0-0.6-1.4-0.8-1.7-1.2-1.3-1.5
Delay discounting water rate 6 sec1.01.53.6-1.2-1.5-0.7-1.3-0.5-1.4-0.4-1.9-1.0-1.4-1.3
Locomotor activity0.71.12.4-1.0-1.2-0.6-1.4-0.6-1.1-0.2-1.5-0.6-1.2-1.3
Locomotor testing distance0.81.33.7-1.1-1.2-0.6-1.2-0.1-1.3-0.1-1.9-0.6-1.3-1.4
Locomotor testing rearing0.91.33.1-1.2-1.3-1.1-0.8-0.3-1.3-0.6-1.8-1.1-1.4-1.3
Light reinforcement 10.20.31.2-0.2-0.5-0.4-0.9-1.1-0.2-0.2-0.3-0.7-0.4-0.1
Light reinforcement 20.30.51.4-0.4-0.4-1.01.10.1-0.2-1.20.5-0.9-0.3-0.1
Reaction time number correct0.50.71.81.10.80.9-0.20.21.11.30.70.60.81.1
Reaction time mean minus median0.40.51.60.40.8-0.1-0.1-1.10.6-0.21.30.30.90.7
Reaction time mean minus median AUC0.40.52.90.20.5-0.1-1.0-1.70.3-0.10.70.00.50.4
Reaction time num false alarms0.40.62.4-0.6-0.6-0.1-1.5-0.6-0.70.1-1.30.1-0.7-0.7
Reaction time num false alarms AUC0.30.42.60.0-0.10.6-1.6-0.7-0.10.6-0.70.7-0.2-0.2
Reaction time trials correct on left0.50.71.81.10.80.9-0.20.21.11.30.70.60.81.1
Reaction time trials on left0.50.81.81.10.80.9-0.30.11.11.30.70.60.81.1
Reaction time mean0.20.31.0-0.40.1-0.7-0.4-1.0-0.2-0.80.2-0.60.1-0.3
Reaction time mean AUC0.30.31.0-0.5-0.1-0.9-0.3-1.0-0.3-0.90.1-0.9-0.0-0.3
Median of all reaction times0.10.10.2-0.20.2-0.40.0-0.3-0.1-0.50.2-0.30.3-0.1
Reaction time omissions0.30.42.20.10.30.2-1.3-1.50.0-0.10.20.30.50.0
Reaction time false alarm rate0.30.51.3-0.6-0.5-0.1-1.1-0.4-0.7-0.2-1.10.2-0.7-0.8
Reaction time premature initiation rate3.75.08.82.52.32.50.91.62.43.01.62.42.32.5
Reaction time premature initiations4.66.612.23.02.62.90.41.22.93.52.02.72.72.9
Std. dev. reaction times0.40.63.4-0.4-0.1-0.7-1.1-1.8-0.3-0.90.3-0.50.0-0.3
Reaction time trials completed0.50.81.81.10.80.9-0.30.11.11.30.70.60.81.1
Reaction time trials AUC0.40.61.61.00.70.8-0.20.20.91.30.60.50.71.0
Social response proportion0.10.10.40.50.40.10.20.10.50.60.30.20.20.6
Social responses0.20.20.90.40.20.3-0.9-0.90.30.50.00.10.10.4
Social time0.20.21.20.2-0.20.3-1.1-0.90.00.2-0.20.1-0.30.1
Conditioned locomotion0.50.61.10.70.80.90.40.40.70.80.71.00.80.7
Cocaine response after cond. corrected0.70.82.3-0.9-1.0-0.3-0.50.3-1.2-0.5-1.5-0.4-1.0-1.2
Cocaine response after cond. not corrected0.60.71.8-0.9-0.8-0.7-0.40.3-1.0-0.5-1.3-0.7-0.8-1.0
Cocaine response before conditioning0.30.40.80.50.7-0.50.2-0.40.90.30.9-0.30.70.9
Saline control response2.12.94.81.91.71.90.30.51.92.21.61.71.81.9
Condit. Reinf. active minus inactive responses0.30.40.9-0.6-0.6-0.80.1-0.6-0.5-1.0-0.1-1.0-0.6-0.5
Condit. Reinf. active-inactive response ratio0.80.82.5-0.9-0.8-1.11.00.2-0.7-1.60.1-0.9-0.8-0.8
Condit. Reinf. active responses0.00.00.10.10.0-0.00.0-0.30.2-0.00.2-0.4-0.00.2
Condit. Reinf. inactive responses0.20.31.00.60.30.5-0.9-0.40.51.0-0.3-0.00.30.5
Condit. Reinf. lever presses0.81.11.91.11.10.61.00.41.30.81.40.51.11.3
Condit. Reinf. lever reinforcers received0.10.10.30.40.30.20.1-0.40.50.20.5-0.10.30.5
Pavlov. Cond. lever latency0.40.61.2-0.8-0.8-0.3-1.1-0.9-0.8-0.6-0.9-0.2-0.8-0.9
Pavlov. Cond. magazine entry latency3.54.06.02.32.41.60.60.32.42.02.21.82.42.4
Pavlov. Cond. change in total contacts1.21.63.31.41.60.61.10.41.60.81.80.41.61.6
Pavlov. Cond. index score2.12.84.51.82.01.01.30.72.01.42.11.12.02.1
Pavlov. Cond. latency score1.92.54.01.71.90.91.40.81.91.22.01.11.91.9
Pavlov. Cond. lever contacts0.30.40.70.70.80.10.30.00.80.50.90.10.80.8
Pavlov. Cond. magazine entry number5.97.210.4-3.0-3.2-2.2-1.2-0.7-3.2-2.5-3.2-2.4-3.2-3.2
Pavlov. Cond. intertrial magazine entries1.51.92.8-1.4-1.6-1.2-0.8-1.0-1.5-1.6-1.3-1.4-1.7-1.5
Pavlov. Cond. lever-magazine prob. diff.2.43.14.82.02.21.11.20.72.11.52.21.22.12.2
Pavlov. Cond. response bias1.31.72.91.51.60.80.60.31.61.21.60.91.61.7
Conditioned reinforcement - actives2.12.03.3-1.7-1.3-1.8-0.4-0.9-1.5-1.8-0.8-1.7-1.4-1.6
Conditioned reinforcement - inactives0.80.91.6-1.1-0.8-1.30.80.3-0.9-1.2-0.4-1.2-1.0-0.9
Conditioned locomotion1.82.23.5-1.9-1.5-1.60.50.4-1.6-1.6-1.3-1.6-1.5-1.9
Intermittent access intake day 1-15 change1.51.52.4-1.2-1.0-1.5-1.2-1.5-1.1-1.6-0.5-1.5-1.0-1.0
Intermittent access intake escalation1.00.91.7-0.9-0.8-1.2-1.0-1.3-0.8-1.3-0.3-1.2-0.7-0.8
Intermittent access intake escalation 20.20.20.9-0.10.0-0.4-0.5-0.9-0.0-0.50.5-0.30.1-0.0
Intermitt. access day 1 inactive lever presses1.51.72.4-1.5-1.5-1.40.0-0.1-1.4-1.5-1.2-1.4-1.5-1.4
Intermitt. access day 15 inactive lever presses0.40.42.60.20.1-0.11.61.20.4-0.00.6-0.20.20.5
Intermitt. access escalation Index0.20.20.8-0.3-0.3-0.10.10.5-0.4-0.1-0.9-0.2-0.4-0.4
Intermittent access day 1 total infusions1.51.75.4-1.2-1.0-1.02.32.2-1.0-0.9-0.8-0.7-1.0-1.0
Intermittent access day 15 total infusions2.93.35.4-2.2-1.9-2.30.70.3-1.9-2.2-1.3-2.0-1.9-2.0
Intermittent access terminal intake (last 3 days)0.91.02.8-1.0-0.7-1.21.71.2-0.7-1.2-0.1-0.9-0.7-0.8
Intermittent access total infusions1.11.32.6-1.2-1.0-1.31.61.2-1.0-1.2-0.5-1.0-0.9-1.0
Intermittent access day 1 locomotion1.21.26.0-0.5-0.3-0.22.42.5-0.4-0.2-0.50.1-0.3-0.5
Intermittent access day 15 total locomotion0.50.52.0-0.7-0.3-0.61.41.2-0.4-0.50.0-0.4-0.3-0.6
Intermittent access total locomotion1.31.48.1-0.6-0.2-0.52.92.5-0.3-0.50.2-0.3-0.2-0.4
Intermittent access standard deviation1.51.62.3-1.4-1.2-1.5-1.0-1.3-1.2-1.5-0.7-1.3-1.2-1.4
Cocaine induced anxiety0.20.20.70.50.50.30.40.20.50.30.80.40.50.5
Post-drug Anxiety0.50.61.60.80.90.60.30.00.90.61.30.60.90.9
Baseline Anxiety0.91.01.41.21.11.2-0.10.11.11.20.91.11.11.1
Lifetime Intake1.11.22.0-1.2-1.0-1.21.41.2-1.0-1.1-0.8-0.8-1.0-1.0
Incentive Sensitization - Responses0.20.21.30.10.3-0.01.10.80.30.00.60.10.30.3
Incentive Sensitization - Breakpoint0.20.21.30.00.2-0.21.20.80.2-0.10.5-0.10.20.2
Progressive ratio test 1 active lever presses1.91.93.1-1.8-1.5-1.6-0.3-0.4-1.6-1.6-1.2-1.2-1.5-1.7
Progressive ratio test 1 breakpoint2.12.23.4-1.9-1.6-1.7-0.4-0.5-1.7-1.7-1.2-1.3-1.6-1.8
Progressive ratio test 1 inactive lever presses0.10.10.60.10.20.30.70.80.10.3-0.00.50.10.1
Progressive ratio test 2 active lever presses1.61.72.6-1.6-1.4-1.60.60.2-1.4-1.6-0.8-1.3-1.3-1.5
Progressive ratio test 2 breakpoint2.42.74.2-2.0-1.8-2.00.1-0.3-1.8-2.0-1.2-1.7-1.7-1.9
Progressive ratio test 2 inactive lever presses0.70.81.8-1.0-0.8-1.11.30.9-0.8-1.1-0.3-0.7-0.8-0.8
Total sessions with >9 infusions1.61.82.5-1.6-1.4-1.40.70.9-1.5-1.3-1.5-1.1-1.4-1.5
Short access day 1 total inactive lever presses0.80.91.3-1.1-0.8-0.90.81.0-1.0-0.8-1.0-0.7-1.0-1.1
Short access day 10 total inactive lever presses2.02.24.0-1.6-1.7-1.3-0.7-0.4-1.7-1.3-2.0-1.4-1.7-1.7
Short access day 1 total infusions0.91.01.4-1.1-1.0-1.00.80.9-1.0-0.9-1.2-0.7-1.1-1.0
Short access day 10 total infusions0.91.04.1-0.7-0.5-0.52.02.0-0.5-0.4-0.5-0.3-0.5-0.6
Short access total infusions0.70.82.1-0.9-0.7-0.61.31.5-0.8-0.5-0.9-0.3-0.7-0.8
Short access day 1 locomotion0.60.73.8-0.00.20.21.82.00.10.2-0.10.30.20.0
Short access day 10 total locomotion0.40.42.5-0.10.20.21.51.6-0.00.1-0.00.10.1-0.0
Short access total locomotion0.80.94.40.20.40.52.02.10.20.40.10.60.40.2
Compulsive drug intake1.21.22.41.41.01.4-0.9-0.51.11.50.21.30.91.3
One hour access (0.3 mA shock)3.33.95.5-2.3-2.3-2.30.50.1-2.2-2.3-1.7-2.1-2.2-2.1
One hour access (shock baseline)4.55.28.7-2.8-2.5-2.80.2-0.4-2.5-3.0-1.5-2.5-2.3-2.6
Number of responses in last shaping day0.00.00.2-0.1-0.00.1-0.20.1-0.20.1-0.40.3-0.1-0.2
Context. condit. distance diff. score0.40.51.1-0.7-0.6-0.10.40.9-0.9-0.4-1.0-0.4-0.8-1.0
Locomotion velocity, session 10.10.10.3-0.1-0.00.5-0.10.5-0.20.4-0.40.2-0.2-0.3
Locomotion distance, session 10.60.82.10.80.61.30.91.40.51.00.31.00.60.6
Locomotion velocity, session 22.42.83.91.91.62.01.11.11.81.71.62.01.61.8
Locomotion distance, session 20.20.31.00.60.31.00.00.40.40.70.11.00.30.4
Locomotion velocity, session 30.91.05.00.60.20.81.82.20.50.80.30.70.40.5
Locomotion distance, session 30.10.10.40.3-0.10.30.20.60.30.6-0.10.20.20.3
Stereotopy head waving bouts, day 30.70.83.7-0.3-0.50.31.71.9-0.5-0.5-0.40.4-0.5-0.6
Stereotopy head waving duration, day 30.40.51.7-0.4-0.60.41.01.3-0.7-0.4-0.30.4-0.6-0.7
Locomotion velocity, session 70.20.20.9-0.1-0.30.10.90.9-0.3-0.4-0.10.1-0.2-0.2
Locomotion distance, session 70.20.31.0-0.4-0.40.20.51.0-0.5-0.1-0.80.1-0.4-0.5
Stereotopy head waving bouts, day 70.20.31.10.30.30.41.00.60.3-0.20.80.40.20.2
Stereotopy head waving duration, day 71.82.23.91.61.71.31.21.01.61.32.01.51.51.5
Locomotion velocity, session 80.20.20.7-0.2-0.30.5-0.8-0.2-0.40.2-0.60.3-0.3-0.5
Locomotion distance, session 80.30.51.7-0.6-0.60.11.01.3-0.7-0.4-0.7-0.1-0.7-0.8
Degree of sensitization distance0.40.42.2-0.3-0.10.11.41.5-0.4-0.3-0.30.1-0.3-0.4
Degree of sensitization stereotypy0.80.92.21.01.10.70.90.41.10.51.50.81.01.0
Condit. Reinf. active minus inactive responses0.91.01.31.11.11.00.50.41.11.11.10.91.11.1
Condit. Reinf. active-inactive response ratio0.30.40.60.60.70.8-0.4-0.30.60.70.60.50.70.6
Condit. Reinf. active responses0.81.01.71.01.10.81.20.81.10.71.30.81.01.1
Condit. Reinf. inactive responses0.30.32.0-0.10.0-0.61.40.90.1-0.40.4-0.3-0.00.1
Incentive salience index mean1.21.51.81.31.31.11.21.11.31.31.31.01.21.3
Condit. Reinf. lever presses0.81.12.01.00.90.71.41.41.11.01.00.70.91.1
Time in familiar zone, hab. session 10.10.10.50.10.4-0.20.60.70.30.4-0.1-0.10.30.3
Time in novel zone, hab. session 11.31.21.8-1.1-1.3-0.9-1.1-0.7-1.2-0.9-1.3-1.1-1.2-1.2
Total zone transitions, hab. session 10.20.31.00.70.61.0-0.1-0.10.60.50.50.80.50.5
Total locomotion distance, hab. session 10.20.20.9-0.2-0.30.20.90.8-0.4-0.6-0.3-0.0-0.4-0.4
Locomotion velocity, hab. session 10.10.20.60.30.30.70.80.60.2-0.00.30.60.20.2
Time in familiar zone, hab. session 20.60.61.9-0.5-0.5-0.9-1.4-1.0-0.40.2-1.0-1.0-0.4-0.4
Time in novel zone, hab. session 20.80.81.80.70.61.01.31.30.60.40.91.00.60.6
Total zone transitions, hab. session 21.41.82.81.51.31.51.01.51.31.70.81.31.31.4
Total locomotion distance, hab. session 20.30.31.70.40.20.61.01.30.30.5-0.10.40.20.3
Locomotion velocity, hab. session 20.20.31.60.2-0.00.51.11.30.10.2-0.10.30.00.2
Novel to familiar place preference ratio2.12.24.01.61.51.31.20.81.61.12.01.81.31.7
Novelty place preference1.31.32.71.21.10.91.00.61.30.81.71.41.01.3
Time in novel zone, NPP test1.41.42.51.31.21.01.10.71.30.91.61.51.01.4
Total zone transitions, NPP test1.01.52.51.31.21.60.50.81.21.31.01.51.21.2
Total locomotion distance, NPP test0.10.20.60.20.00.60.50.80.00.3-0.20.60.10.1
Locomotion velocity, NPP test0.10.10.30.1-0.10.60.20.4-0.10.1-0.20.5-0.0-0.0
Pavlov. Cond. lever latency1.21.52.4-1.2-1.3-0.9-1.6-1.3-1.3-1.1-1.3-1.0-1.3-1.2
Pavlov. Cond. magazine entry latency1.01.32.71.01.20.51.61.11.30.71.30.71.31.2
Pavlov. Cond. change in total contacts0.40.41.60.30.6-0.11.30.50.5-0.11.00.10.60.5
Pavlov. Cond. index score0.50.61.20.70.90.40.90.41.00.61.10.41.00.9
Pavlov. Cond. latency score0.40.61.00.70.80.41.00.60.90.60.90.40.90.8
Pavlov. Cond. lever contacts0.30.30.90.50.60.21.00.80.60.50.50.20.60.5
Pavlov. Cond. magazine entry number0.50.61.6-0.7-1.0-0.3-0.50.2-1.0-0.4-1.2-0.5-1.1-0.9
Pavlov. Cond. intertrial magazine entries0.10.20.90.10.2-0.1-0.5-1.00.1-0.30.60.20.00.2
Pavlov. Cond. lever-magazine prob. diff.0.70.81.60.81.00.51.00.51.10.61.30.61.11.0
Pavlov. Cond. response bias0.60.71.40.81.00.30.90.41.10.51.20.51.11.0
Bone: apparent density0.40.72.30.50.90.61.51.40.50.40.60.40.80.6
Bone surface1.93.35.71.82.01.42.41.81.81.22.31.31.91.8
Bone volume1.01.64.71.01.30.72.21.61.10.51.60.61.31.1
Bone: connectivity density1.72.63.81.51.71.41.91.91.61.41.61.41.71.6
Bone: cortical apparent density0.50.61.00.80.91.0-0.8-0.70.70.70.70.70.80.7
Bone: cortical area0.81.21.81.31.10.81.20.81.30.91.30.81.11.3
Bone: cortical porosity0.20.21.0-0.2-0.20.1-0.8-1.0-0.2-0.4-0.20.0-0.2-0.4
Bone: cortical porosity0.20.21.00.10.20.4-0.9-1.00.10.00.10.40.2-0.0
Bone: cortical thickness2.64.46.42.52.22.3-0.6-0.42.42.51.92.22.22.4
Bone: cortical thickness0.50.51.10.80.70.9-0.8-0.40.71.10.20.70.80.7
Bone: cortical tissue density0.60.71.20.91.01.1-0.9-0.80.80.70.80.80.90.8
Bone: elastic displacement0.70.71.9-0.7-0.7-0.4-1.4-1.1-0.8-0.4-1.2-0.6-0.8-0.8
Bone: elastic work0.60.81.71.00.91.3-0.30.00.91.30.31.10.90.9
Bone: endosteal estimation1.43.16.5-1.6-1.5-1.72.62.1-1.6-1.8-1.3-1.7-1.5-1.5
Bone: endosteal perimeter1.94.06.6-1.9-1.9-2.22.61.8-1.8-2.4-1.3-2.2-1.8-1.8
Bone: final force2.03.23.81.91.91.61.91.61.91.62.01.61.91.9
Bone: final moment1.93.13.81.81.81.61.81.51.91.61.91.51.81.9
Bone: marrow area1.53.36.0-1.7-1.6-1.82.52.1-1.7-1.9-1.4-1.8-1.6-1.7
Bone: maximum diameter0.30.52.80.50.30.21.71.00.5-0.10.90.20.40.5
Bone: maximum force2.95.09.72.12.11.73.12.72.21.72.41.72.22.2
Bone: maximum moment2.74.78.82.02.11.63.02.52.21.72.31.72.12.2
Bone: minimum diameter1.01.86.4-0.9-0.9-1.22.52.1-0.9-1.2-0.7-1.3-0.9-0.8
Bone: periosteal estimation0.51.06.3-0.1-0.2-0.42.51.9-0.1-0.60.2-0.5-0.1-0.0
Bone: periosteal perimeter0.20.42.60.0-0.1-0.41.61.00.0-0.50.2-0.4-0.00.1
Bone: post-yield work1.31.89.7-0.7-0.3-1.03.12.4-0.5-1.20.1-0.9-0.2-0.4
Bone: stiffness0.81.32.91.11.10.71.71.11.20.71.50.61.21.3
Bone: tissue strength0.20.20.7-0.4-0.4-0.8-0.3-0.2-0.2-0.1-0.2-0.8-0.5-0.1
Bone: trabecular number1.01.53.80.91.20.91.91.71.00.81.40.81.21.0
Bone: trabecular spacing0.60.72.9-0.5-0.8-0.7-1.7-1.3-0.5-0.1-0.9-0.6-0.6-0.5
Bone: trabecular thickness0.30.41.0-0.7-0.2-0.70.50.1-0.6-1.0-0.5-0.9-0.3-0.6
Bone: trabecular tissue density4.25.97.3-2.5-2.7-2.1-2.1-1.9-2.7-2.5-2.4-2.3-2.6-2.7
Breakpoint value in progressive ratio session1.61.83.21.51.61.3-0.2-0.51.61.11.81.31.51.5
Distance traveled before self-admin2.02.23.61.71.61.40.90.41.71.31.91.11.81.8
Distance traveled after self-admin0.30.30.60.60.60.3-0.0-0.40.70.40.80.10.70.8
Delta time in closed arm before/after self-admin1.61.53.31.21.01.80.41.21.01.80.31.81.01.0
Delta time in open arm before/after self-admin1.31.33.01.21.30.90.70.11.30.61.70.91.41.3
Diff in mean of infusions in LGA sessions1.51.72.31.41.51.5-0.6-0.71.41.21.41.51.51.3
Extinction: sum of active levers before priming3.53.55.12.12.22.00.80.62.11.82.11.72.32.1
Active lever presses in extinction session 62.22.14.11.61.81.30.2-0.31.81.22.01.21.81.6
Delta distance traveled before/after self-admin0.50.61.2-0.8-0.7-0.7-0.8-0.5-0.8-0.5-1.1-0.8-0.8-0.8
Delta ambulatory time before/after self-admin0.91.01.9-1.0-1.0-0.8-1.1-0.7-1.0-0.7-1.4-0.9-1.1-1.1
Time in closed arm before self-admin0.10.10.3-0.10.0-0.50.50.00.0-0.50.3-0.5-0.10.1
Time in closed arm after self-admin0.40.41.1-0.6-0.8-0.6-0.10.2-0.8-0.5-1.0-0.5-0.9-0.7
Time in open arm before self-admin0.91.03.0-0.9-1.1-0.2-1.4-0.5-1.1-0.1-1.7-0.3-1.1-1.1
Time in open arm after self-admin0.20.21.00.10.10.4-1.0-0.90.10.20.10.30.2-0.0
Sum of active levers in priming session hrs 5-61.11.13.21.01.20.5-0.2-1.11.20.21.80.51.21.2
Time to tail flick, vehicle, before self-admin0.90.93.20.70.70.71.81.60.70.40.80.80.70.8
Time to tail flick, vehicle, after self-admin0.50.51.20.70.50.90.71.10.60.90.20.80.60.6
Time to tail flick, test, before self-admin0.90.93.80.60.40.91.61.90.40.80.10.90.40.5
Time to tail flick, test, after self-admin0.10.10.1-0.2-0.2-0.2-0.2-0.3-0.3-0.4-0.3-0.3-0.3-0.1
Delta time to tail flick, vehicle, before/after SA0.00.00.20.1-0.00.2-0.4-0.1-0.00.4-0.30.10.0-0.1
Delta time to tail flick, test, before/after SA0.60.63.3-0.2-0.1-0.4-1.5-1.8-0.1-0.50.2-0.4-0.1-0.2
Ambulatory time before self-admin1.71.84.01.51.61.00.80.11.60.92.00.91.61.6
Ambulatory time after self-admin0.20.30.60.40.60.00.60.20.60.10.8-0.20.60.6
Total heroin consumption3.23.85.02.22.22.2-0.5-0.72.21.92.22.12.22.1
Area under the delay curve0.10.10.70.10.00.30.70.8-0.00.2-0.20.30.00.1
Delay disc. indifference point, 0s delay0.40.41.6-0.5-0.6-0.10.81.3-0.6-0.1-0.9-0.1-0.6-0.5
Delay disc. indifference point, 16s delay0.20.21.20.30.30.21.10.90.30.10.40.20.30.4
Delay disc. indifference point, 2s delay0.30.30.8-0.5-0.5-0.40.90.9-0.5-0.5-0.5-0.5-0.5-0.4
Delay disc. indifference point, 24s delay0.10.10.60.30.20.5-0.00.40.20.7-0.10.40.20.2
Delay disc. indifference point, 4s delay0.50.51.30.50.41.00.61.10.30.90.01.10.40.4
Delay disc. indifference point, 8s delay0.30.30.8-0.5-0.7-0.1-0.40.1-0.7-0.1-0.9-0.0-0.7-0.6
Delay discount exponential model param0.10.10.6-0.1-0.0-0.3-0.6-0.80.0-0.20.2-0.3-0.0-0.1
Delay discount hyperbolic model param0.10.10.7-0.1-0.0-0.3-0.7-0.90.0-0.30.1-0.4-0.0-0.1
Fecal boli incidents, locomotor time 10.30.41.2-0.5-0.3-0.90.5-0.4-0.4-1.10.2-1.0-0.3-0.3
Change in fecal boli incidents, locomotor task0.60.61.8-0.7-0.9-0.1-0.40.5-0.9-0.1-1.4-0.1-0.9-1.0
Time >=10cm from walls, locomotor time 12.02.03.7-1.6-1.4-1.80.90.2-1.4-1.9-0.8-1.8-1.4-1.6
Bouts of movement, locomotor time 10.70.84.60.30.40.1-1.7-2.20.40.10.70.30.40.1
Total resting periods, locomotor time 10.50.53.00.30.50.1-1.2-1.70.40.10.80.20.50.2
Rest time, locomotor task time 11.31.51.8-1.2-1.3-1.1-0.9-1.2-1.3-1.4-1.2-1.3-1.3-1.0
Distance moved, locomotor task time 10.30.30.60.50.50.40.60.80.50.60.40.40.60.3
Vertical activity count, locomotor time 10.50.51.0-0.9-0.8-0.8-0.1-0.0-0.8-0.7-0.8-0.8-0.7-1.0
Time >=10cm from walls, locomotor time 20.20.20.7-0.4-0.2-0.7-0.2-0.8-0.2-0.70.3-0.7-0.2-0.4
Bouts of movement, locomotor time 21.11.22.01.31.21.1-0.0-0.21.21.11.21.11.21.4
Total resting periods, locomotor time 20.50.61.10.90.90.7-0.0-0.20.80.70.80.70.81.1
Rest time, locomotor task time 22.83.34.4-2.0-2.1-1.8-0.6-0.7-2.1-2.0-2.0-1.9-2.0-1.9
Distance moved, locomotor task time 20.40.50.70.70.80.5-0.6-0.60.80.70.80.60.80.5
Vertical activity count, locomotor time 20.30.32.0-0.0-0.10.1-1.4-1.1-0.10.3-0.40.1-0.1-0.3
Weight adjusted by age1.61.82.71.41.50.91.20.91.51.21.61.21.51.5
Seeking ratio, delayed vs. immediate footshock0.00.00.10.20.20.20.40.30.00.1-0.10.10.10.3
Locomotion in novel chamber1.92.34.5-1.8-1.5-2.10.60.1-1.5-1.9-0.9-1.9-1.5-1.5
Locomotion in novel chamber post-restriction2.22.73.9-1.9-2.0-1.4-0.7-0.8-2.0-1.9-1.5-1.4-1.9-1.9
Progressive ratio0.10.20.80.20.2-0.20.90.70.30.10.4-0.4-0.00.4
Food seeking constrained by brief footshock0.10.10.4-0.2-0.30.0-0.3-0.0-0.4-0.0-0.7-0.2-0.4-0.2
Seeking ratio, punishment vs. effort0.20.20.9-0.3-0.40.3-0.9-0.4-0.50.1-0.80.3-0.3-0.5
Run reversals in cocaine runway, females1.21.23.40.90.81.31.21.80.81.40.11.20.70.7
Run reversals in cocaine runway, males0.60.50.7-0.7-0.8-0.5-0.7-0.6-0.8-0.7-0.8-0.6-0.8-0.8
Latency to leave start box in cocaine runway0.40.40.8-0.6-0.6-0.60.90.9-0.5-0.4-0.4-0.5-0.6-0.6
Latency to leave start box in cocaine runway, F0.00.00.20.00.10.00.50.40.10.10.20.10.00.1
Latency to leave start box in cocaine runway, M2.82.73.6-1.9-1.9-1.8-0.2-0.1-1.8-1.5-1.7-1.8-1.9-1.9
Cd content in liver1.21.32.3-1.3-1.1-1.2-0.2-0.4-1.4-1.5-0.7-1.2-1.1-1.4
Co content in liver2.53.07.9-1.5-1.5-1.1-2.8-2.2-1.6-0.9-2.1-1.5-1.4-1.7
Cu content in liver0.20.30.70.50.40.8-0.5-0.10.40.80.40.80.40.4
Fe content in liver0.00.00.1-0.2-0.1-0.10.20.0-0.1-0.30.20.1-0.1-0.2
K content in liver1.41.42.91.11.00.91.71.51.21.01.10.80.91.2
Mg content in liver0.90.93.30.60.50.71.81.80.70.60.70.50.50.6
Mn content in liver2.12.44.51.61.71.31.00.71.81.52.11.41.51.8
Na content in liver0.60.61.10.90.70.60.90.60.90.51.10.50.81.0
Rb content in liver1.21.52.4-1.3-1.5-1.1-0.00.4-1.4-0.9-1.5-1.3-1.5-1.4
Se content in liver0.40.52.20.40.50.11.30.60.6-0.11.50.40.50.6
Sr content in liver5.34.86.42.52.42.30.40.12.42.12.52.52.42.5
Zn content in liver3.74.15.22.22.22.31.41.02.21.82.22.12.32.2