Xpnpep3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000068666 0.09 0.05 1.1e-06 0.02 0.02 0.02 0.02 1.0e-03 1.9e-03 2.2e-03 2.0e-03
2 Adipose alternative polyA ENSRNOT00000111293 0.08 0.05 1.4e-06 0.02 0.02 0.02 0.02 1.3e-03 2.7e-03 2.4e-03 2.0e-03
3 Adipose isoform ratio ENSRNOT00000068666 0.05 0.03 2.3e-04 0 0.02 0.01 0.01 1.5e-01 3.7e-03 6.2e-02 3.7e-02
4 Adipose mRNA stability ENSRNOG00000019196 0.03 0.02 2.5e-03 0.01 0.01 0 0.01 6.9e-03 2.7e-02 7.5e-02 2.5e-02
5 BLA gene expression ENSRNOG00000019196 0.11 0.06 2.2e-05 0.08 0.08 0.08 0.08 5.3e-05 6.0e-05 4.8e-05 6.2e-05
6 LHb isoform ratio ENSRNOT00000111293 0.16 0.11 7.4e-03 0.04 0.02 -0 0.01 4.6e-02 1.2e-01 4.0e-01 2.3e-01
7 NAcc gene expression ENSRNOG00000019196 0.05 0.04 4.1e-03 0.02 0.02 0.02 0.02 1.2e-02 1.2e-02 2.2e-02 6.9e-03
8 PL gene expression ENSRNOG00000019196 0.06 0.04 9.6e-05 0.05 0.04 0.05 0.05 6.9e-05 2.2e-04 1.2e-04 6.3e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail1.65.28.2-2.02.0-1.82.72.22.91.82.6
BMI without tail0.10.31.30.2-0.20.30.6-0.11.1-0.10.6
Body weight1.87.710.7-3.03.0-2.62.82.93.32.42.0
Epididymis fat weight3.58.111.1-3.33.3-1.92.83.22.83.11.6
Glucose0.30.40.80.9-0.90.7-0.3-0.8-0.1-0.90.0
Heart weight1.92.84.5-1.51.5-1.22.11.52.10.82.1
Left kidney weight11.131.940.7-6.46.4-5.35.36.25.75.44.0
Right kidney weight11.833.541.2-6.46.4-5.95.56.35.85.24.6
Tail length0.20.50.80.6-0.60.9-0.8-0.8-0.4-0.4-0.9
Length with tail0.41.52.5-1.61.6-1.20.71.31.11.3-0.1
Length without tail1.63.45.3-2.32.3-2.21.32.11.21.90.8
Liver weight, left0.71.12.5-1.11.1-0.21.01.11.21.6-0.4
Liver weight, right2.54.28.8-2.22.2-0.32.32.32.13.00.3
Parametrial fat weight0.20.40.6-0.50.5-0.30.70.60.70.50.8
Retroperitoneal fat weight4.916.221.3-4.64.6-3.13.94.54.04.32.8
Intraocular pressure0.30.40.9-0.80.8-0.60.40.70.50.90.2
Extensor digitorum longus weight0.20.81.51.1-1.11.2-0.4-1.0-0.5-0.8-0.7
Soleus weight0.30.92.00.9-0.9-0.0-1.4-0.9-1.2-0.9-0.5
Tibialis anterior weight0.51.82.71.6-1.60.8-1.3-1.5-1.4-1.6-0.4
Tibia length0.72.04.3-1.71.7-2.10.91.61.11.10.1
Number of licking bursts0.80.91.80.9-0.90.6-1.3-1.0-1.1-0.8-0.9
Food consumed during 24 hour testing period2.12.54.0-1.61.6-2.01.51.61.71.11.5
Times rat made contact with spout0.60.61.4-0.80.8-1.20.40.80.40.70.9
Mean time between licks in bursts0.60.81.10.9-0.91.1-0.8-1.0-0.9-0.8-0.6
Mean num. licks in bursts2.12.53.0-1.71.7-1.41.61.71.41.61.3
Std. dev. time between licks in bursts1.61.93.41.5-1.50.5-1.5-1.6-1.5-1.8-0.6
Water consumed over 24 hours0.60.71.6-0.90.9-1.30.60.90.80.80.3
Indifference point 0 sec0.40.71.51.1-1.10.5-0.6-1.0-0.4-1.2-0.3
Indifference point AUC0.40.51.70.2-0.2-0.5-1.3-0.4-1.0-0.5-0.8
Indifference point function ln k1.21.73.4-1.11.1-0.21.81.31.51.61.0
Indifference point function log k1.21.73.4-1.11.1-0.21.81.31.51.61.0
Delay discounting total patch changes 0 sec0.60.91.91.2-1.20.5-0.8-1.1-0.5-1.4-0.4
Delay discounting total patch changes 12 sec0.10.10.20.2-0.2-0.5-0.4-0.20.0-0.40.0
Delay discounting total patch changes 18 sec0.40.51.70.5-0.5-0.6-0.8-0.6-0.5-1.30.0
Delay discounting total patch changes 24 sec0.50.61.30.7-0.70.1-1.0-0.8-0.7-1.1-0.6
Delay discounting total patch changes 6 sec0.71.03.11.0-1.0-0.6-1.2-1.0-0.7-1.8-0.3
Delay discounting time to switch 0 sec0.10.10.5-0.10.10.10.70.10.7-0.30.2
Delay discounting water rate 0 sec0.20.30.40.6-0.60.1-0.6-0.6-0.6-0.5-0.0
Delay discounting water rate 12 sec0.50.81.11.0-1.01.1-0.7-1.0-0.8-0.5-0.8
Delay discounting water rate 18 sec1.31.82.61.4-1.40.6-1.6-1.4-1.4-1.4-1.1
Delay discounting water rate 24 sec0.00.00.20.1-0.1-0.10.1-0.00.20.10.4
Delay discounting water rate 6 sec1.52.23.01.5-1.51.7-1.5-1.5-1.6-0.5-1.7
Locomotor activity1.82.94.4-1.81.8-1.32.01.92.11.60.7
Locomotor testing distance0.00.00.10.1-0.10.30.1-0.0-0.10.3-0.4
Locomotor testing rearing1.21.82.7-1.41.4-0.91.61.51.41.50.9
Light reinforcement 10.10.31.20.4-0.40.0-0.2-0.3-0.3-0.6-1.1
Light reinforcement 20.81.02.1-1.11.1-0.01.21.10.91.50.6
Reaction time number correct1.21.73.71.0-1.01.5-1.4-1.0-1.8-0.3-1.9
Reaction time mean minus median0.10.10.30.0-0.00.20.60.10.30.1-0.2
Reaction time mean minus median AUC0.70.81.9-0.80.8-0.11.40.91.21.10.5
Reaction time num false alarms0.20.31.10.4-0.40.7-0.1-0.4-0.1-0.5-1.1
Reaction time num false alarms AUC0.40.61.80.6-0.60.9-0.4-0.6-0.5-0.6-1.3
Reaction time trials correct on left1.21.73.71.0-1.01.5-1.4-1.0-1.8-0.3-1.9
Reaction time trials on left1.31.94.01.0-1.01.5-1.4-1.1-1.9-0.3-2.0
Reaction time mean0.10.20.50.4-0.40.7-0.0-0.4-0.4-0.4-0.2
Reaction time mean AUC0.10.10.40.4-0.40.6-0.1-0.4-0.4-0.3-0.1
Median of all reaction times0.20.30.60.5-0.50.8-0.3-0.5-0.7-0.6-0.2
Reaction time omissions0.50.61.10.7-0.70.9-0.8-0.7-1.0-0.5-0.8
Reaction time false alarm rate0.10.10.30.1-0.10.20.4-0.00.5-0.2-0.0
Reaction time premature initiation rate0.20.31.30.4-0.4-0.6-0.4-0.4-0.0-1.10.2
Reaction time premature initiations0.30.40.80.5-0.5-0.0-0.8-0.6-0.7-0.9-0.5
Std. dev. reaction times0.10.20.6-0.20.20.10.80.30.50.40.1
Reaction time trials completed1.31.94.01.0-1.01.5-1.4-1.1-1.9-0.3-2.0
Reaction time trials AUC1.01.43.20.8-0.81.3-1.2-0.9-1.6-0.2-1.8
Social response proportion0.40.51.5-0.10.1-0.11.20.31.1-0.11.0
Social responses0.10.20.50.4-0.40.0-0.3-0.4-0.2-0.5-0.7
Social time1.72.23.11.7-1.71.1-1.5-1.7-1.5-1.8-0.6
Conditioned locomotion0.40.50.7-0.80.8-0.40.80.80.70.7-0.2
Cocaine response after cond. corrected0.10.10.1-0.30.3-0.40.40.30.2-0.00.0
Cocaine response after cond. not corrected0.00.00.1-0.00.00.00.40.10.2-0.1-0.1
Cocaine response before conditioning0.20.30.90.7-0.70.9-0.1-0.6-0.2-0.2-0.2
Saline control response0.30.41.80.4-0.41.10.0-0.3-0.10.2-1.4
Condit. Reinf. active minus inactive responses0.20.20.80.0-0.0-0.9-0.6-0.1-0.6-0.60.3
Condit. Reinf. active-inactive response ratio0.30.31.4-0.30.3-1.2-0.00.30.1-0.30.8
Condit. Reinf. active responses0.20.31.5-0.60.6-1.2-0.00.5-0.10.00.3
Condit. Reinf. inactive responses0.40.41.0-0.80.8-1.00.30.80.20.60.2
Condit. Reinf. lever presses0.30.40.70.7-0.70.2-0.7-0.7-0.7-0.8-0.3
Condit. Reinf. lever reinforcers received0.10.21.0-0.30.3-1.0-0.20.3-0.2-0.20.2
Pavlov. Cond. lever latency0.91.22.1-1.31.3-0.90.91.30.81.50.5
Pavlov. Cond. magazine entry latency2.52.95.11.9-1.90.7-1.9-2.0-1.7-2.3-0.5
Pavlov. Cond. change in total contacts0.50.72.70.7-0.7-0.7-0.5-0.7-0.4-1.60.4
Pavlov. Cond. index score1.72.23.61.7-1.70.8-1.5-1.7-1.4-1.9-0.5
Pavlov. Cond. latency score2.12.74.41.8-1.80.9-1.8-1.9-1.6-2.1-0.4
Pavlov. Cond. lever contacts0.71.01.71.3-1.30.9-0.7-1.2-0.7-1.3-0.4
Pavlov. Cond. magazine entry number1.11.42.3-1.21.2-0.41.51.31.21.50.2
Pavlov. Cond. intertrial magazine entries2.53.24.7-1.81.8-1.71.81.91.61.52.2
Pavlov. Cond. lever-magazine prob. diff.1.72.23.61.7-1.70.9-1.5-1.7-1.4-1.9-0.6
Pavlov. Cond. response bias0.71.02.41.2-1.20.4-0.9-1.2-0.7-1.5-0.2
Conditioned reinforcement - actives0.10.10.4-0.40.4-0.6-0.00.4-0.40.3-0.1
Conditioned reinforcement - inactives0.50.61.70.7-0.7-0.2-0.8-0.8-0.6-1.30.1
Conditioned locomotion1.72.04.2-1.31.3-2.11.51.51.20.71.4
Intermittent access intake day 1-15 change0.50.50.80.7-0.70.9-0.7-0.7-0.8-0.5-0.5
Intermittent access intake escalation0.60.60.90.7-0.70.9-0.7-0.7-0.9-0.6-0.6
Intermittent access intake escalation 20.30.30.50.5-0.50.7-0.4-0.5-0.7-0.6-0.5
Intermitt. access day 1 inactive lever presses0.40.41.5-0.30.3-0.80.40.20.8-0.41.2
Intermitt. access day 15 inactive lever presses0.40.52.3-0.20.2-1.0-0.10.20.60.01.5
Intermitt. access escalation Index0.10.10.20.1-0.10.0-0.4-0.20.0-0.40.2
Intermittent access day 1 total infusions0.70.82.1-0.90.9-1.50.50.80.80.21.0
Intermittent access day 15 total infusions0.10.10.50.2-0.2-0.4-0.4-0.2-0.3-0.70.1
Intermittent access terminal intake (last 3 days)0.00.00.1-0.20.2-0.3-0.00.2-0.2-0.2-0.0
Intermittent access total infusions0.30.41.2-0.60.6-1.10.30.50.4-0.20.6
Intermittent access day 1 locomotion0.40.41.0-0.30.3-1.00.70.50.60.11.0
Intermittent access day 15 total locomotion0.20.20.6-0.40.4-0.80.50.50.20.10.3
Intermittent access total locomotion0.70.71.8-0.80.8-1.40.70.80.70.21.0
Intermittent access standard deviation0.60.61.4-0.60.6-0.80.80.60.90.21.2
Cocaine induced anxiety2.12.43.8-1.61.6-1.31.61.61.51.11.9
Post-drug Anxiety0.60.60.8-0.80.8-0.90.80.80.90.40.8
Baseline Anxiety2.02.23.31.6-1.61.3-1.4-1.5-1.2-1.2-1.8
Lifetime Intake1.01.12.8-1.01.0-1.70.60.90.80.11.4
Incentive Sensitization - Responses0.30.30.90.4-0.40.5-0.9-0.6-0.8-0.40.2
Incentive Sensitization - Breakpoint0.20.20.50.2-0.20.3-0.7-0.3-0.6-0.20.4
Progressive ratio test 1 active lever presses0.80.82.3-0.90.9-1.50.30.80.30.01.3
Progressive ratio test 1 breakpoint0.50.61.4-0.90.9-1.20.30.70.20.21.0
Progressive ratio test 1 inactive lever presses0.60.63.3-0.40.4-0.70.60.40.6-0.31.8
Progressive ratio test 2 active lever presses0.20.20.5-0.10.1-0.7-0.7-0.0-0.7-0.30.5
Progressive ratio test 2 breakpoint0.30.31.0-0.40.4-1.0-0.40.2-0.4-0.21.0
Progressive ratio test 2 inactive lever presses0.60.71.30.8-0.80.0-1.1-0.9-1.0-1.10.6
Total sessions with >9 infusions1.92.04.4-1.61.6-2.10.91.41.00.81.6
Short access day 1 total inactive lever presses0.80.93.3-0.60.6-1.80.80.70.8-0.60.9
Short access day 10 total inactive lever presses0.10.10.5-0.10.1-0.40.50.20.70.10.2
Short access day 1 total infusions1.11.12.4-1.01.0-1.40.80.91.10.41.6
Short access day 10 total infusions1.82.03.4-1.51.5-1.91.21.41.10.61.7
Short access total infusions2.83.15.9-1.71.7-2.31.31.61.60.72.4
Short access day 1 locomotion0.30.31.2-0.40.4-0.50.30.30.50.01.1
Short access day 10 total locomotion0.30.30.80.7-0.70.40.5-0.40.6-0.20.9
Short access total locomotion1.71.74.5-1.01.0-1.41.41.11.40.62.1
Compulsive drug intake2.62.64.51.5-1.51.1-2.0-1.6-2.1-1.1-1.6
One hour access (0.3 mA shock)0.30.40.60.7-0.70.4-0.7-0.7-0.8-0.7-0.3
One hour access (shock baseline)0.30.30.5-0.50.5-0.30.70.50.60.20.7
Number of responses in last shaping day1.11.13.51.0-1.0-0.3-0.9-1.1-0.7-1.90.7
Context. condit. distance diff. score5.87.111.8-2.92.9-1.32.82.92.83.41.4
Locomotion velocity, session 10.50.51.60.0-0.0-0.7-0.9-0.2-0.9-0.4-1.3
Locomotion distance, session 13.14.06.91.8-1.80.7-2.6-2.0-2.6-1.8-2.0
Locomotion velocity, session 20.20.20.4-0.40.4-0.60.50.50.40.20.3
Locomotion distance, session 22.73.86.62.0-2.00.3-2.3-2.1-2.3-2.6-0.7
Locomotion velocity, session 30.30.41.5-0.50.50.40.40.50.01.2-0.6
Locomotion distance, session 31.51.63.20.9-0.91.3-1.7-1.1-1.8-0.1-1.6
Stereotopy head waving bouts, day 30.91.12.0-1.21.2-1.41.11.21.10.40.5
Stereotopy head waving duration, day 33.13.85.9-2.12.1-1.92.42.22.21.20.9
Locomotion velocity, session 70.30.40.7-0.70.7-0.30.50.70.30.80.4
Locomotion distance, session 70.10.10.6-0.20.2-0.5-0.10.2-0.4-0.10.8
Stereotopy head waving bouts, day 72.02.33.2-1.81.8-0.91.61.71.61.7-0.5
Stereotopy head waving duration, day 71.72.13.3-1.61.6-0.31.81.61.71.8-0.2
Locomotion velocity, session 81.41.72.6-1.41.4-1.61.31.51.11.10.7
Locomotion distance, session 80.50.71.6-0.80.8-0.20.90.90.91.20.4
Degree of sensitization distance3.73.86.7-1.71.7-1.82.31.82.20.72.6
Degree of sensitization stereotypy1.31.42.7-1.41.4-0.41.11.31.11.7-0.7
Condit. Reinf. active minus inactive responses0.10.20.30.4-0.40.0-0.6-0.4-0.5-0.40.3
Condit. Reinf. active-inactive response ratio0.20.20.4-0.50.5-0.20.40.50.40.70.3
Condit. Reinf. active responses1.41.72.41.5-1.51.2-1.2-1.5-1.2-1.4-0.1
Condit. Reinf. inactive responses2.83.44.82.2-2.21.9-1.5-2.1-1.7-1.9-0.6
Incentive salience index mean0.40.50.90.8-0.80.3-0.9-0.8-0.8-0.80.4
Condit. Reinf. lever presses0.81.01.51.2-1.20.6-1.1-1.2-0.9-1.20.2
Time in familiar zone, hab. session 10.20.20.8-0.30.3-0.9-0.70.0-0.3-0.2-0.1
Time in novel zone, hab. session 10.70.72.5-0.50.50.31.60.71.30.70.2
Total zone transitions, hab. session 14.46.210.22.3-2.32.0-3.2-2.5-3.1-1.5-2.5
Total locomotion distance, hab. session 12.73.97.11.7-1.71.9-2.2-1.8-2.3-1.0-2.7
Locomotion velocity, hab. session 13.04.46.12.0-2.01.8-2.4-2.1-2.5-1.4-2.4
Time in familiar zone, hab. session 20.20.20.7-0.00.00.8-0.2-0.10.00.5-0.7
Time in novel zone, hab. session 20.10.10.6-0.00.0-0.80.30.1-0.0-0.50.4
Total zone transitions, hab. session 21.72.24.61.3-1.3-0.0-2.1-1.5-1.8-1.6-1.0
Total locomotion distance, hab. session 21.11.52.51.3-1.30.4-1.4-1.3-1.3-1.6-0.7
Locomotion velocity, hab. session 21.92.64.01.7-1.70.6-1.9-1.8-1.7-2.0-1.0
Novel to familiar place preference ratio2.22.33.1-1.71.7-0.91.81.71.71.70.0
Novelty place preference3.13.24.4-2.02.0-1.12.02.12.02.10.1
Time in novel zone, NPP test3.84.05.3-2.22.2-1.32.22.32.22.30.2
Total zone transitions, NPP test4.15.910.22.2-2.21.6-3.2-2.5-3.1-1.8-2.4
Total locomotion distance, NPP test1.82.53.71.6-1.61.0-1.9-1.6-1.9-1.4-1.5
Locomotion velocity, NPP test2.63.75.01.9-1.91.5-2.2-2.0-2.2-1.7-1.7
Pavlov. Cond. lever latency0.81.11.6-1.21.2-0.91.01.21.01.1-0.0
Pavlov. Cond. magazine entry latency0.60.81.30.9-0.90.1-1.2-1.0-1.0-1.00.5
Pavlov. Cond. change in total contacts1.21.32.71.2-1.2-0.0-1.3-1.2-1.2-1.60.6
Pavlov. Cond. index score0.30.40.90.6-0.6-0.1-0.7-0.6-0.6-0.81.0
Pavlov. Cond. latency score0.30.40.70.6-0.60.1-0.6-0.6-0.5-0.70.9
Pavlov. Cond. lever contacts1.11.31.91.4-1.40.8-1.1-1.3-1.1-1.30.4
Pavlov. Cond. magazine entry number0.40.51.1-0.60.6-0.11.00.70.80.6-0.7
Pavlov. Cond. intertrial magazine entries1.01.22.31.2-1.20.4-1.1-1.2-1.1-1.5-0.8
Pavlov. Cond. lever-magazine prob. diff.0.40.50.90.7-0.70.1-0.9-0.7-0.8-0.80.8
Pavlov. Cond. response bias0.60.71.00.9-0.90.2-1.0-0.9-0.9-1.00.7
Bone: apparent density0.20.30.60.6-0.60.3-0.4-0.6-0.2-0.7-0.5
Bone surface0.30.51.70.5-0.5-0.1-0.8-0.5-0.6-0.8-1.3
Bone volume0.10.10.40.2-0.2-0.1-0.3-0.2-0.0-0.4-0.6
Bone: connectivity density0.00.10.20.3-0.3-0.1-0.1-0.20.1-0.4-0.4
Bone: cortical apparent density0.71.01.51.0-1.01.0-1.2-1.0-1.2-0.3-0.9
Bone: cortical area1.42.13.4-1.51.5-1.81.41.51.60.91.0
Bone: cortical porosity0.60.61.5-0.70.7-0.51.20.81.10.40.4
Bone: cortical porosity1.51.73.4-1.21.2-1.21.81.41.60.70.7
Bone: cortical thickness0.40.61.9-0.60.6-1.10.50.60.70.31.4
Bone: cortical thickness0.40.51.6-0.60.6-1.30.20.50.40.11.2
Bone: cortical tissue density0.70.91.50.9-0.91.0-1.2-0.9-1.2-0.3-0.9
Bone: elastic displacement0.10.10.5-0.10.10.10.00.10.00.2-0.7
Bone: elastic work2.12.84.4-1.61.6-1.82.01.72.10.91.2
Bone: endosteal estimation0.51.01.5-1.11.1-1.21.11.11.10.3-0.7
Bone: endosteal perimeter1.32.73.7-1.91.9-1.51.91.91.91.3-0.2
Bone: final force2.03.37.0-2.02.0-2.61.41.81.70.91.7
Bone: final moment2.13.47.6-2.02.0-2.71.41.91.70.91.7
Bone: marrow area0.51.11.7-1.11.1-1.31.21.11.20.3-0.7
Bone: maximum diameter3.36.18.7-2.72.7-3.02.52.72.81.71.3
Bone: maximum force3.15.310.4-2.42.4-3.22.12.42.31.12.1
Bone: maximum moment3.25.611.1-2.52.5-3.32.12.42.41.22.1
Bone: minimum diameter0.40.71.3-1.01.0-1.10.90.91.00.40.0
Bone: periosteal estimation1.12.33.7-1.71.7-1.91.61.71.80.80.2
Bone: periosteal perimeter3.15.17.0-2.52.5-2.32.42.52.71.80.8
Bone: post-yield work0.30.42.2-0.30.3-1.50.20.40.4-0.40.7
Bone: stiffness2.03.26.1-1.71.7-2.51.71.71.90.61.8
Bone: tissue strength0.10.10.2-0.40.4-0.40.20.40.30.40.1
Bone: trabecular number0.10.10.3-0.20.20.30.20.30.30.5-0.6
Bone: trabecular spacing1.31.74.3-1.31.3-2.10.91.21.00.31.5
Bone: trabecular thickness0.20.21.00.5-0.51.0-0.0-0.4-0.0-0.2-0.3
Bone: trabecular tissue density1.21.62.81.5-1.51.1-0.9-1.5-1.2-1.7-0.4
Breakpoint value in progressive ratio session0.10.10.40.4-0.40.10.2-0.3-0.1-0.70.4
Distance traveled before self-admin0.20.21.10.4-0.4-0.1-0.5-0.40.1-0.31.0
Distance traveled after self-admin0.30.31.20.4-0.4-1.1-0.3-0.30.0-0.90.4
Delta time in closed arm before/after self-admin1.21.21.6-1.31.3-1.20.71.10.61.01.2
Delta time in open arm before/after self-admin0.60.61.01.0-1.00.80.1-0.7-0.3-0.9-0.9
Diff in mean of infusions in LGA sessions0.20.20.6-0.10.1-0.6-0.8-0.2-0.8-0.10.2
Extinction: sum of active levers before priming0.00.00.20.1-0.1-0.30.1-0.0-0.2-0.40.2
Active lever presses in extinction session 60.20.20.7-0.20.2-0.40.80.40.3-0.00.7
Delta distance traveled before/after self-admin0.30.31.4-0.40.4-1.20.20.4-0.0-0.0-0.6
Delta ambulatory time before/after self-admin0.40.42.0-0.40.4-1.40.20.4-0.1-0.3-0.7
Time in closed arm before self-admin4.34.99.22.5-2.51.5-1.9-2.6-1.8-3.0-1.3
Time in closed arm after self-admin0.50.50.8-0.60.6-0.90.70.60.70.10.9
Time in open arm before self-admin0.30.31.5-0.60.60.3-0.00.50.11.2-0.4
Time in open arm after self-admin0.50.51.60.7-0.71.30.3-0.3-0.30.1-1.2
Sum of active levers in priming session hrs 5-60.00.00.10.1-0.10.20.1-0.0-0.0-0.20.2
Time to tail flick, vehicle, before self-admin0.10.10.3-0.20.2-0.4-0.40.0-0.2-0.2-0.6
Time to tail flick, vehicle, after self-admin1.21.33.80.9-0.91.2-0.7-0.9-0.8-1.0-1.9
Time to tail flick, test, before self-admin0.10.10.5-0.40.4-0.1-0.40.1-0.00.1-0.7
Time to tail flick, test, after self-admin1.21.21.41.2-1.21.1-1.0-1.2-0.9-1.1-1.1
Delta time to tail flick, vehicle, before/after SA0.10.10.30.4-0.40.60.4-0.20.3-0.4-0.0
Delta time to tail flick, test, before/after SA3.02.73.51.9-1.91.7-1.4-1.8-1.5-1.4-1.2
Ambulatory time before self-admin0.40.40.80.8-0.80.4-0.9-0.8-0.2-0.50.6
Ambulatory time after self-admin1.21.32.61.3-1.3-0.2-1.2-1.1-0.9-1.6-0.8
Total heroin consumption0.10.10.6-0.10.1-0.8-0.10.2-0.4-0.10.5
Area under the delay curve0.40.41.20.3-0.3-0.3-1.0-0.5-0.8-1.1-0.3
Delay disc. indifference point, 0s delay0.90.91.6-0.70.7-1.01.20.81.30.21.2
Delay disc. indifference point, 16s delay1.71.72.81.1-1.10.4-1.6-1.2-1.6-1.7-1.2
Delay disc. indifference point, 2s delay0.10.20.6-0.30.3-0.8-0.10.20.3-0.40.5
Delay disc. indifference point, 24s delay0.70.61.3-0.20.2-0.9-1.1-0.0-1.2-0.5-1.1
Delay disc. indifference point, 4s delay0.30.31.00.2-0.2-0.6-0.6-0.4-0.3-1.00.4
Delay disc. indifference point, 8s delay0.80.91.60.7-0.70.3-1.3-0.9-1.2-1.2-0.6
Delay discount exponential model param0.50.51.2-0.40.40.21.10.60.91.10.5
Delay discount hyperbolic model param0.30.41.1-0.30.30.30.90.50.71.00.3
Fecal boli incidents, locomotor time 10.30.41.40.4-0.4-0.4-0.6-0.4-0.5-1.2-0.4
Change in fecal boli incidents, locomotor task0.50.41.5-0.70.7-0.4-0.10.6-0.11.2-0.6
Time >=10cm from walls, locomotor time 10.30.30.7-0.60.6-0.90.50.50.30.20.4
Bouts of movement, locomotor time 11.01.11.7-1.31.3-1.10.71.20.51.20.9
Total resting periods, locomotor time 10.70.81.2-1.01.0-1.00.60.90.40.81.1
Rest time, locomotor task time 10.80.92.7-0.70.7-1.00.80.81.00.41.6
Distance moved, locomotor task time 10.30.30.6-0.60.60.20.80.60.20.8-0.1
Vertical activity count, locomotor time 10.00.00.10.0-0.00.10.1-0.0-0.3-0.2-0.3
Time >=10cm from walls, locomotor time 20.10.10.30.3-0.3-0.2-0.4-0.4-0.1-0.5-0.3
Bouts of movement, locomotor time 20.70.71.8-0.50.5-0.50.90.61.00.81.4
Total resting periods, locomotor time 20.50.61.7-0.50.5-0.70.70.50.80.61.3
Rest time, locomotor task time 20.10.10.40.2-0.2-0.2-0.6-0.3-0.3-0.30.0
Distance moved, locomotor task time 20.50.51.0-0.70.7-0.01.00.80.70.90.5
Vertical activity count, locomotor time 20.20.20.5-0.40.4-0.50.70.50.50.30.1
Weight adjusted by age0.20.20.6-0.30.30.1-0.40.1-0.40.8-0.6
Seeking ratio, delayed vs. immediate footshock2.22.53.31.8-1.81.3-1.6-1.8-1.7-1.5-0.8
Locomotion in novel chamber2.73.37.02.2-2.22.6-0.9-1.9-1.2-0.8-1.9
Locomotion in novel chamber post-restriction0.70.91.41.0-1.01.2-1.0-1.0-1.0-0.5-0.6
Progressive ratio0.10.10.40.4-0.40.1-0.2-0.40.0-0.60.3
Food seeking constrained by brief footshock1.51.82.9-1.41.4-1.41.11.41.70.91.1
Seeking ratio, punishment vs. effort0.60.71.1-0.90.9-1.00.70.90.80.70.6
Run reversals in cocaine runway, females1.11.12.70.9-0.91.1-1.1-1.0-1.0-0.4-1.7
Run reversals in cocaine runway, males0.40.41.3-0.50.5-0.80.10.60.01.1-0.3
Latency to leave start box in cocaine runway0.70.81.3-0.80.8-0.11.10.90.81.20.8
Latency to leave start box in cocaine runway, F0.10.20.50.4-0.40.7-0.2-0.4-0.40.0-0.4
Latency to leave start box in cocaine runway, M3.63.45.0-1.91.9-1.02.22.01.91.91.9
Cd content in liver0.50.61.3-0.90.9-0.10.60.80.81.10.6
Co content in liver0.20.30.4-0.50.5-0.60.40.50.50.20.7
Cu content in liver3.94.75.92.4-2.41.8-2.2-2.4-2.1-2.3-1.7
Fe content in liver0.10.10.20.1-0.1-0.00.3-0.10.4-0.3-0.4
K content in liver0.60.61.00.9-0.90.4-1.0-0.9-0.8-1.00.0
Mg content in liver1.01.02.01.2-1.20.5-1.0-1.2-0.9-1.4-0.0
Mn content in liver0.10.10.5-0.30.30.1-0.10.2-0.10.7-0.2
Na content in liver2.52.73.51.9-1.91.4-1.6-1.9-1.6-1.7-1.0
Rb content in liver0.10.10.20.0-0.0-0.4-0.4-0.2-0.2-0.4-0.0
Se content in liver0.81.02.30.9-0.91.5-1.0-1.0-1.0-0.2-1.0
Sr content in liver0.80.81.51.0-1.01.2-0.8-0.9-1.1-0.4-0.3
Zn content in liver1.41.62.21.3-1.31.1-1.3-1.3-1.2-1.1-1.5