Hub : Genes

Ap3d1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000018977 0.18 0.1 0.0e+00 0.19 0.19 0.19 0.19 1.5e-20 6.3e-21 9.5e-21 9.3e-21
2 BLA mRNA stability ENSRNOG00000018977 0.05 0.04 4.8e-03 0.02 0.02 0.01 0.01 4.3e-02 3.2e-02 5.8e-02 6.2e-02
3 Brain mRNA stability ENSRNOG00000018977 0.15 0.08 0.0e+00 0.18 0.18 0.17 0.18 1.3e-16 2.0e-16 7.8e-16 2.0e-16
4 LHb mRNA stability ENSRNOG00000018977 0.16 0.11 4.4e-04 0.08 0.08 0.04 0.1 7.5e-03 4.9e-03 4.0e-02 3.0e-03
5 Liver gene expression ENSRNOG00000018977 0.12 0.07 3.6e-13 0.07 0.09 0.08 0.08 2.5e-08 3.8e-10 1.3e-09 1.7e-09
6 Liver isoform ratio ENSRNOT00000025878 0.08 0.05 2.5e-10 0.08 0.09 0.08 0.09 1.4e-09 8.0e-10 2.2e-09 1.2e-09
7 Liver intron excision ratio chr7:8999998:9000364 0.03 0.03 9.2e-05 0.03 0.03 0.02 0.02 5.2e-04 4.3e-04 1.3e-03 1.4e-03
8 Liver mRNA stability ENSRNOG00000018977 0.04 0.03 8.8e-05 0.04 0.04 0.03 0.03 6.4e-05 6.6e-05 1.8e-04 1.2e-04
9 NAcc gene expression ENSRNOG00000018977 0.03 0.02 7.7e-03 0.02 0.02 0.01 0.02 2.0e-02 9.0e-03 5.1e-02 2.1e-02
10 NAcc mRNA stability ENSRNOG00000018977 0.09 0.05 6.5e-07 0.06 0.08 0.08 0.08 2.0e-05 8.3e-07 1.4e-06 1.5e-06
11 PL mRNA stability ENSRNOG00000018977 0.12 0.08 2.6e-10 0.14 0.13 0.13 0.13 1.4e-10 7.0e-10 7.6e-10 5.2e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail6.621.423.54.4-4.6-4.6-4.64.8-4.6-4.5-4.54.8-4.8-4.6
BMI without tail2.24.57.31.8-2.0-2.0-2.02.6-2.0-1.9-1.92.2-2.7-2.1
Body weight1.24.95.52.1-2.2-2.2-2.12.4-2.2-2.2-2.12.3-2.3-2.3
Epididymis fat weight0.20.50.9-0.80.70.80.8-0.60.80.80.7-0.60.50.9
Glucose1.32.02.31.4-1.4-1.4-1.41.5-1.4-1.4-1.31.5-1.5-1.4
Heart weight0.40.60.8-0.90.80.80.8-0.50.80.80.8-0.70.40.8
Left kidney weight0.00.00.20.00.10.00.0-0.30.10.00.2-0.20.5-0.1
Right kidney weight1.43.94.3-1.92.01.92.0-2.12.01.92.0-2.02.11.8
Tail length3.310.111.0-3.23.23.33.3-3.03.23.23.3-3.22.83.2
Length with tail1.96.87.7-2.52.72.52.6-2.82.62.52.6-2.72.82.4
Length without tail0.00.10.60.10.1-0.00.0-0.60.1-0.0-0.0-0.30.8-0.0
Liver weight, left2.43.94.61.8-2.0-1.9-1.92.1-2.0-1.9-1.92.1-2.2-1.8
Liver weight, right1.93.13.31.8-1.8-1.8-1.81.7-1.8-1.8-1.81.8-1.6-1.8
Parametrial fat weight0.50.91.1-1.01.01.01.0-0.81.01.01.0-1.00.70.9
Retroperitoneal fat weight0.30.91.20.9-1.0-0.9-1.01.1-1.0-0.9-1.01.0-1.1-0.8
Intraocular pressure0.10.20.4-0.60.30.50.50.20.40.50.5-0.1-0.50.5
Extensor digitorum longus weight4.417.622.73.9-4.2-3.9-4.14.7-4.1-4.0-3.94.4-4.8-4.1
Soleus weight9.427.529.25.1-5.2-5.2-5.25.4-5.3-5.2-5.25.3-5.3-5.2
Tibialis anterior weight1.24.14.52.0-2.0-2.0-2.12.1-2.0-2.0-1.92.1-2.1-2.1
Tibia length1.02.72.9-1.71.71.71.6-1.61.71.71.7-1.71.51.7
Number of licking bursts0.00.10.2-0.20.10.20.20.30.10.20.20.1-0.50.2
Food consumed during 24 hour testing period0.50.60.80.7-0.7-0.7-0.70.9-0.8-0.7-0.70.8-0.9-0.7
Times rat made contact with spout0.10.20.50.2-0.3-0.3-0.30.6-0.3-0.3-0.30.4-0.7-0.3
Mean time between licks in bursts4.56.36.6-2.62.52.62.6-2.42.62.62.6-2.52.32.6
Mean num. licks in bursts0.10.10.10.3-0.2-0.3-0.30.1-0.3-0.3-0.30.2-0.1-0.3
Std. dev. time between licks in bursts0.60.81.3-0.70.90.80.8-1.10.80.80.8-1.01.10.8
Water consumed over 24 hours0.70.81.11.1-0.9-1.0-1.00.7-1.0-1.0-1.00.8-0.5-1.0
Indifference point 0 sec0.10.20.30.5-0.5-0.5-0.50.4-0.5-0.5-0.60.5-0.3-0.5
Indifference point AUC1.01.21.4-1.11.11.21.1-1.01.11.11.2-1.10.91.0
Indifference point function ln k0.20.30.40.5-0.5-0.6-0.60.6-0.6-0.6-0.60.6-0.7-0.6
Indifference point function log k0.20.30.40.5-0.5-0.6-0.60.6-0.6-0.6-0.60.6-0.7-0.6
Delay discounting total patch changes 0 sec0.10.20.20.4-0.4-0.4-0.40.3-0.4-0.4-0.50.4-0.3-0.3
Delay discounting total patch changes 12 sec0.20.30.70.3-0.5-0.4-0.40.7-0.5-0.4-0.40.6-0.8-0.4
Delay discounting total patch changes 18 sec1.21.51.7-1.21.21.21.3-1.21.21.21.2-1.21.21.3
Delay discounting total patch changes 24 sec0.10.10.1-0.30.30.30.3-0.30.30.30.3-0.30.30.3
Delay discounting total patch changes 6 sec0.20.30.5-0.50.50.60.6-0.70.60.50.5-0.60.70.6
Delay discounting time to switch 0 sec1.82.73.51.8-1.7-1.8-1.71.1-1.7-1.8-1.91.5-0.8-1.7
Delay discounting water rate 0 sec0.10.20.4-0.60.40.60.50.30.40.50.6-0.2-0.50.5
Delay discounting water rate 12 sec0.71.13.10.6-0.9-0.8-0.81.5-0.9-0.8-0.71.1-1.8-0.7
Delay discounting water rate 18 sec0.50.71.2-1.10.71.00.90.20.80.90.9-0.4-0.71.0
Delay discounting water rate 24 sec0.20.32.0-0.2-0.10.10.01.1-0.10.10.10.5-1.40.1
Delay discounting water rate 6 sec0.60.91.4-1.21.01.11.0-0.31.01.11.2-0.70.01.1
Locomotor activity3.14.97.3-1.92.22.12.1-2.62.12.02.1-2.42.72.0
Locomotor testing distance1.93.24.3-1.61.81.71.7-2.01.81.71.7-1.92.11.7
Locomotor testing rearing0.00.10.1-0.40.30.30.3-0.00.30.30.3-0.2-0.10.4
Light reinforcement 15.810.612.5-3.13.23.13.2-3.53.23.23.2-3.43.53.2
Light reinforcement 22.02.63.3-1.51.61.51.5-1.81.61.51.5-1.71.81.6
Reaction time number correct0.40.51.80.4-0.6-0.5-0.51.1-0.6-0.5-0.50.8-1.3-0.5
Reaction time mean minus median0.81.01.3-1.01.11.11.0-0.91.01.01.1-1.00.81.0
Reaction time mean minus median AUC0.00.00.10.3-0.1-0.2-0.3-0.2-0.1-0.2-0.1-0.00.3-0.2
Reaction time num false alarms0.10.10.40.0-0.0-0.0-0.10.5-0.1-0.1-0.00.2-0.7-0.1
Reaction time num false alarms AUC0.10.10.70.0-0.1-0.1-0.10.7-0.1-0.1-0.10.3-0.8-0.1
Reaction time trials correct on left0.40.51.80.4-0.6-0.5-0.51.1-0.6-0.5-0.50.8-1.3-0.5
Reaction time trials on left0.40.51.80.4-0.6-0.5-0.51.1-0.6-0.5-0.50.8-1.3-0.5
Reaction time mean0.00.00.10.3-0.1-0.2-0.2-0.0-0.2-0.2-0.20.00.1-0.2
Reaction time mean AUC0.00.10.10.4-0.2-0.3-0.30.0-0.3-0.3-0.30.10.1-0.3
Median of all reaction times0.30.50.60.8-0.6-0.7-0.70.5-0.7-0.8-0.80.6-0.3-0.7
Reaction time omissions0.20.30.6-0.50.50.60.5-0.70.60.50.6-0.60.70.4
Reaction time false alarm rate0.00.00.00.1-0.1-0.1-0.10.2-0.1-0.1-0.10.1-0.2-0.1
Reaction time premature initiation rate1.31.72.1-1.41.31.41.4-1.11.41.41.3-1.31.01.4
Reaction time premature initiations0.81.21.7-1.31.11.21.2-0.61.11.21.1-0.90.31.3
Std. dev. reaction times0.20.30.3-0.40.60.50.4-0.50.50.50.6-0.60.50.5
Reaction time trials completed0.40.51.80.4-0.6-0.5-0.51.1-0.6-0.5-0.50.8-1.3-0.5
Reaction time trials AUC0.30.51.80.3-0.5-0.4-0.41.1-0.5-0.4-0.40.7-1.4-0.4
Social response proportion0.50.61.2-0.60.70.60.7-1.00.70.70.6-0.81.10.7
Social responses6.68.510.5-2.72.92.82.9-3.22.92.82.8-3.13.22.8
Social time0.60.80.90.9-1.0-0.9-0.80.8-0.9-0.9-0.90.9-0.8-0.9
Conditioned locomotion1.21.43.00.9-1.1-1.1-1.01.6-1.1-1.0-1.11.3-1.7-1.0
Cocaine response after cond. corrected4.55.18.71.9-2.2-2.0-2.12.8-2.2-2.0-2.02.4-2.9-2.1
Cocaine response after cond. not corrected4.85.39.31.9-2.2-2.1-2.12.8-2.2-2.1-2.12.5-3.0-2.1
Cocaine response before conditioning0.40.50.7-0.60.70.60.7-0.80.70.60.6-0.80.80.7
Saline control response0.00.00.10.1-0.2-0.2-0.10.3-0.2-0.1-0.20.2-0.3-0.1
Condit. Reinf. active minus inactive responses2.73.43.8-2.01.91.91.9-1.51.91.91.9-1.81.41.9
Condit. Reinf. active-inactive response ratio0.30.30.5-0.70.50.70.6-0.10.60.70.7-0.3-0.10.6
Condit. Reinf. active responses2.43.33.6-1.81.91.91.8-1.71.91.81.9-1.81.61.8
Condit. Reinf. inactive responses1.11.31.6-1.11.21.11.1-1.21.21.11.1-1.21.21.1
Condit. Reinf. lever presses2.63.64.0-2.01.92.02.0-1.61.92.02.0-1.91.52.0
Condit. Reinf. lever reinforcers received1.92.62.9-1.71.71.71.7-1.41.71.71.7-1.61.21.7
Pavlov. Cond. lever latency0.81.11.31.0-1.1-1.0-1.11.0-1.1-1.0-1.01.1-0.9-1.1
Pavlov. Cond. magazine entry latency0.40.50.6-0.70.80.70.7-0.70.70.70.7-0.80.70.7
Pavlov. Cond. change in total contacts0.81.11.3-1.11.11.11.1-0.91.11.11.1-1.10.91.1
Pavlov. Cond. index score0.91.21.4-1.11.21.11.1-1.01.11.11.1-1.10.91.1
Pavlov. Cond. latency score0.81.01.2-1.01.11.01.0-1.01.01.01.0-1.11.01.0
Pavlov. Cond. lever contacts0.81.11.3-1.11.11.11.1-0.91.11.11.1-1.10.81.1
Pavlov. Cond. magazine entry number0.70.91.00.9-1.0-1.0-0.90.9-0.9-0.9-1.01.0-0.9-0.9
Pavlov. Cond. intertrial magazine entries0.20.30.70.4-0.5-0.4-0.40.7-0.5-0.4-0.40.6-0.8-0.4
Pavlov. Cond. lever-magazine prob. diff.0.91.11.3-1.01.11.11.1-1.01.11.11.1-1.11.01.1
Pavlov. Cond. response bias1.92.73.0-1.71.71.71.7-1.41.71.71.7-1.61.31.7
Conditioned reinforcement - actives2.52.52.8-1.51.61.71.7-1.61.61.61.7-1.61.51.1
Conditioned reinforcement - inactives0.40.50.90.5-0.6-0.6-0.60.9-0.6-0.6-0.60.7-0.9-0.9
Conditioned locomotion7.99.510.5-3.03.13.23.1-3.13.13.13.2-3.13.02.8
Intermittent access intake day 1-15 change7.57.48.0-2.72.82.82.8-2.62.82.82.8-2.72.52.6
Intermittent access intake escalation7.67.58.6-2.92.82.92.9-2.42.82.92.9-2.72.12.6
Intermittent access intake escalation 29.19.110.2-3.23.13.23.1-2.63.13.23.2-2.92.43.0
Intermitt. access day 1 inactive lever presses0.40.40.8-0.70.70.90.7-0.30.70.70.9-0.50.20.4
Intermitt. access day 15 inactive lever presses0.60.60.8-0.80.80.80.8-0.70.80.80.8-0.80.60.9
Intermitt. access escalation Index0.40.30.50.7-0.6-0.7-0.60.2-0.6-0.7-0.70.4-0.1-0.7
Intermittent access day 1 total infusions0.10.10.10.3-0.2-0.3-0.20.2-0.3-0.3-0.30.2-0.2-0.2
Intermittent access day 15 total infusions2.32.52.9-1.71.61.71.7-1.41.61.71.7-1.61.31.6
Intermittent access terminal intake (last 3 days)1.21.31.6-1.21.21.21.3-1.11.21.21.2-1.21.01.1
Intermittent access total infusions0.30.30.4-0.60.60.60.6-0.40.60.60.6-0.50.40.5
Intermittent access day 1 locomotion0.40.40.5-0.70.70.60.7-0.60.70.70.6-0.60.50.6
Intermittent access day 15 total locomotion4.04.24.6-2.12.12.22.1-2.02.12.12.2-2.11.91.9
Intermittent access total locomotion1.11.21.4-1.11.11.21.1-1.11.11.11.2-1.11.10.9
Intermittent access standard deviation3.43.64.3-1.92.02.11.9-1.72.02.02.1-1.91.51.8
Cocaine induced anxiety0.50.51.4-0.50.60.60.6-1.00.60.60.6-0.81.20.4
Post-drug Anxiety0.20.31.0-0.20.40.30.3-0.80.40.30.3-0.61.00.5
Baseline Anxiety0.10.10.4-0.50.30.30.3-0.10.30.40.3-0.3-0.00.6
Lifetime Intake0.10.10.1-0.30.30.30.4-0.30.30.30.3-0.30.20.2
Incentive Sensitization - Responses0.30.30.6-0.60.60.80.6-0.30.60.70.8-0.50.20.2
Incentive Sensitization - Breakpoint0.40.40.6-0.70.60.80.7-0.40.60.70.8-0.50.30.2
Progressive ratio test 1 active lever presses0.10.10.20.1-0.2-0.2-0.10.4-0.2-0.2-0.20.3-0.4-0.1
Progressive ratio test 1 breakpoint0.10.10.30.2-0.3-0.3-0.30.5-0.3-0.3-0.30.4-0.5-0.2
Progressive ratio test 1 inactive lever presses0.00.00.0-0.10.10.10.1-0.10.10.10.1-0.10.1-0.0
Progressive ratio test 2 active lever presses0.30.30.5-0.60.60.70.6-0.30.60.60.7-0.50.20.3
Progressive ratio test 2 breakpoint0.30.30.5-0.60.60.70.6-0.50.60.60.7-0.60.40.3
Progressive ratio test 2 inactive lever presses0.00.00.1-0.20.20.20.2-0.30.20.20.2-0.20.3-0.0
Total sessions with >9 infusions0.00.00.20.2-0.1-0.1-0.0-0.0-0.1-0.1-0.10.00.1-0.4
Short access day 1 total inactive lever presses0.00.10.1-0.20.20.20.3-0.30.20.20.2-0.20.20.1
Short access day 10 total inactive lever presses0.10.10.2-0.30.20.40.3-0.10.30.30.4-0.20.00.2
Short access day 1 total infusions0.10.10.4-0.10.20.10.3-0.50.20.20.1-0.30.60.0
Short access day 10 total infusions0.00.00.1-0.20.20.20.2-0.00.20.20.2-0.1-0.00.1
Short access total infusions0.00.00.10.0-0.0-0.00.0-0.0-0.0-0.0-0.0-0.00.0-0.2
Short access day 1 locomotion0.90.91.5-0.81.00.90.9-1.20.90.90.9-1.11.20.7
Short access day 10 total locomotion4.75.15.7-2.32.32.42.4-2.12.32.32.4-2.32.01.9
Short access total locomotion1.01.01.1-0.91.01.01.1-1.01.01.01.0-1.01.00.6
Compulsive drug intake1.41.41.91.3-1.2-1.2-1.21.0-1.2-1.2-1.21.1-0.9-1.4
One hour access (0.3 mA shock)0.20.20.30.4-0.4-0.4-0.40.4-0.4-0.4-0.40.4-0.5-0.5
One hour access (shock baseline)0.10.10.2-0.50.40.40.4-0.10.40.40.4-0.30.00.4
Number of responses in last shaping day0.20.20.2-0.40.40.40.5-0.40.40.40.4-0.40.40.1
Context. condit. distance diff. score0.30.30.50.5-0.5-0.6-0.60.7-0.6-0.5-0.50.6-0.7-0.6
Locomotion velocity, session 10.40.41.2-0.30.60.40.4-0.90.50.40.5-0.71.10.5
Locomotion distance, session 10.10.10.90.3-0.1-0.2-0.2-0.7-0.1-0.2-0.1-0.20.9-0.2
Locomotion velocity, session 22.83.26.7-1.41.71.51.5-2.41.71.51.6-1.92.61.7
Locomotion distance, session 21.11.54.6-0.81.00.90.9-1.81.00.91.0-1.32.11.0
Locomotion velocity, session 36.47.47.9-2.72.82.72.7-2.72.82.72.7-2.82.62.8
Locomotion distance, session 30.00.00.0-0.00.00.00.00.10.00.00.10.0-0.2-0.0
Stereotopy head waving bouts, day 34.55.57.0-2.22.32.22.2-2.62.32.22.2-2.42.62.3
Stereotopy head waving duration, day 35.66.87.7-2.52.62.52.5-2.82.62.52.5-2.72.82.7
Locomotion velocity, session 70.60.70.9-0.80.90.80.8-0.80.80.80.8-0.90.80.8
Locomotion distance, session 70.10.10.50.0-0.1-0.1-0.10.5-0.1-0.1-0.10.3-0.7-0.2
Stereotopy head waving bouts, day 70.10.10.20.3-0.1-0.3-0.3-0.2-0.2-0.3-0.30.00.4-0.2
Stereotopy head waving duration, day 70.10.10.8-0.00.20.10.1-0.70.20.10.1-0.40.90.2
Locomotion velocity, session 80.30.41.6-0.20.40.30.3-1.00.40.30.3-0.71.30.4
Locomotion distance, session 80.10.10.4-0.10.20.20.2-0.50.20.20.2-0.30.60.2
Degree of sensitization distance0.40.40.40.6-0.6-0.6-0.60.6-0.6-0.6-0.60.6-0.6-0.6
Degree of sensitization stereotypy2.22.42.81.7-1.5-1.6-1.61.3-1.6-1.6-1.61.5-1.1-1.6
Condit. Reinf. active minus inactive responses4.34.75.0-2.12.22.12.1-2.22.22.22.2-2.22.22.2
Condit. Reinf. active-inactive response ratio2.42.62.9-1.71.71.61.6-1.41.71.71.7-1.61.31.7
Condit. Reinf. active responses3.44.16.0-1.82.01.91.9-2.42.01.91.9-2.12.51.9
Condit. Reinf. inactive responses0.60.72.1-0.50.70.60.6-1.30.70.60.7-0.91.50.7
Incentive salience index mean2.02.43.6-1.31.51.41.4-1.81.51.41.5-1.61.91.4
Condit. Reinf. lever presses0.10.20.60.5-0.2-0.4-0.4-0.5-0.2-0.4-0.2-0.00.8-0.4
Time in familiar zone, hab. session 12.42.32.8-1.61.61.61.5-1.31.51.51.5-1.51.21.7
Time in novel zone, hab. session 11.31.21.71.3-1.1-1.2-1.20.8-1.2-1.2-1.11.0-0.6-1.3
Total zone transitions, hab. session 10.70.92.6-0.60.80.70.7-1.40.80.70.8-1.01.60.8
Total locomotion distance, hab. session 10.70.93.4-0.50.80.60.6-1.60.70.60.6-1.11.80.7
Locomotion velocity, hab. session 11.11.54.2-0.81.11.01.0-1.81.10.91.0-1.32.01.0
Time in familiar zone, hab. session 26.97.28.0-2.82.72.82.7-2.42.82.82.7-2.62.22.8
Time in novel zone, hab. session 25.25.36.02.5-2.3-2.4-2.42.0-2.4-2.4-2.42.2-1.8-2.4
Total zone transitions, hab. session 20.40.50.91.0-0.8-0.8-0.8-0.1-0.7-0.8-0.80.50.4-0.8
Total locomotion distance, hab. session 20.60.92.5-0.60.70.70.7-1.40.80.70.7-1.01.60.8
Locomotion velocity, hab. session 20.60.82.9-0.50.70.60.6-1.40.70.60.6-0.91.70.7
Novel to familiar place preference ratio4.74.95.92.4-2.3-2.3-2.31.9-2.3-2.4-2.32.1-1.6-2.4
Novelty place preference2.93.03.81.9-1.8-1.9-1.81.4-1.8-1.9-1.81.6-1.2-1.9
Time in novel zone, NPP test3.33.44.12.0-1.9-2.0-1.91.5-1.9-2.0-1.91.8-1.3-2.0
Total zone transitions, NPP test0.10.10.20.4-0.3-0.3-0.3-0.3-0.3-0.3-0.30.10.5-0.3
Total locomotion distance, NPP test0.10.20.30.6-0.4-0.5-0.5-0.2-0.4-0.5-0.50.20.4-0.4
Locomotion velocity, NPP test0.10.10.50.3-0.1-0.2-0.2-0.5-0.1-0.2-0.2-0.10.7-0.1
Pavlov. Cond. lever latency0.10.10.2-0.40.30.40.40.10.30.40.4-0.1-0.30.3
Pavlov. Cond. magazine entry latency3.14.04.2-2.02.02.02.0-2.02.02.02.0-2.01.92.1
Pavlov. Cond. change in total contacts0.00.00.1-0.20.20.20.2-0.30.20.20.2-0.20.30.2
Pavlov. Cond. index score0.30.40.9-0.50.60.50.5-0.80.60.50.5-0.70.90.6
Pavlov. Cond. latency score0.30.31.0-0.30.50.40.4-0.90.50.40.4-0.61.00.5
Pavlov. Cond. lever contacts0.10.10.40.3-0.1-0.2-0.2-0.4-0.1-0.2-0.2-0.10.6-0.2
Pavlov. Cond. magazine entry number0.70.91.00.9-0.9-0.9-0.91.0-0.9-0.9-0.90.9-1.0-1.0
Pavlov. Cond. intertrial magazine entries0.20.30.4-0.60.50.60.6-0.20.50.60.6-0.40.10.6
Pavlov. Cond. lever-magazine prob. diff.0.60.81.4-0.70.90.80.8-1.10.80.80.8-1.01.20.9
Pavlov. Cond. response bias1.11.31.5-1.11.11.11.1-1.21.11.11.1-1.21.21.2
Bone: apparent density0.20.30.60.8-0.4-0.6-0.6-0.3-0.5-0.7-0.60.20.6-0.6
Bone surface0.20.42.20.60.0-0.3-0.3-1.0-0.1-0.4-0.3-0.41.5-0.3
Bone volume0.20.42.10.60.0-0.3-0.3-1.0-0.1-0.4-0.3-0.41.4-0.3
Bone: connectivity density0.40.71.11.1-0.8-1.0-1.00.2-0.9-1.0-1.00.60.0-0.9
Bone: cortical apparent density0.81.01.01.0-1.0-1.0-1.01.0-1.0-1.0-1.01.0-1.0-1.0
Bone: cortical area0.71.11.51.2-1.0-1.1-1.10.7-1.1-1.2-1.10.9-0.5-1.1
Bone: cortical porosity0.50.51.0-0.50.70.60.6-0.90.60.60.6-0.81.00.6
Bone: cortical porosity0.00.10.30.2-0.1-0.1-0.1-0.4-0.1-0.2-0.1-0.10.5-0.1
Bone: cortical thickness1.22.02.31.5-1.4-1.5-1.51.3-1.5-1.5-1.51.4-1.1-1.5
Bone: cortical thickness0.10.10.1-0.30.20.30.20.20.20.30.3-0.1-0.30.2
Bone: cortical tissue density0.50.60.70.8-0.8-0.8-0.80.8-0.8-0.8-0.80.8-0.8-0.8
Bone: elastic displacement0.20.30.4-0.50.50.50.5-0.60.50.50.5-0.50.60.5
Bone: elastic work0.20.30.40.6-0.5-0.6-0.60.4-0.6-0.6-0.60.5-0.4-0.6
Bone: endosteal estimation0.20.50.60.8-0.7-0.8-0.80.6-0.7-0.8-0.80.6-0.5-0.8
Bone: endosteal perimeter0.20.30.8-0.40.60.40.4-0.80.50.40.4-0.70.90.5
Bone: final force1.42.42.81.7-1.5-1.6-1.61.3-1.6-1.6-1.61.4-1.1-1.6
Bone: final moment1.11.82.21.5-1.3-1.4-1.41.1-1.4-1.5-1.41.3-1.0-1.5
Bone: marrow area0.30.50.70.8-0.7-0.8-0.80.6-0.8-0.8-0.80.7-0.5-0.8
Bone: maximum diameter0.50.92.1-0.71.00.80.8-1.30.90.80.8-1.11.50.8
Bone: maximum force1.42.42.71.6-1.5-1.6-1.61.4-1.6-1.6-1.61.5-1.3-1.6
Bone: maximum moment1.11.92.21.5-1.3-1.5-1.51.2-1.4-1.5-1.51.3-1.1-1.5
Bone: minimum diameter0.00.10.10.3-0.1-0.3-0.3-0.0-0.2-0.3-0.30.10.1-0.3
Bone: periosteal estimation0.40.91.31.1-0.9-1.1-1.10.6-1.0-1.1-1.10.8-0.4-1.1
Bone: periosteal perimeter0.00.10.40.10.1-0.0-0.0-0.40.0-0.1-0.0-0.20.6-0.0
Bone: post-yield work0.50.70.90.8-0.8-0.8-0.91.0-0.8-0.8-0.80.9-1.0-0.8
Bone: stiffness3.35.35.62.3-2.3-2.3-2.42.2-2.3-2.4-2.32.3-2.1-2.4
Bone: tissue strength1.81.81.91.4-1.4-1.4-1.41.2-1.4-1.4-1.41.3-1.1-1.4
Bone: trabecular number0.40.61.9-0.40.70.60.6-1.20.70.50.6-0.91.40.6
Bone: trabecular spacing0.30.32.0-0.1-0.3-0.1-0.11.1-0.2-0.1-0.10.6-1.4-0.1
Bone: trabecular thickness0.40.50.91.0-0.4-0.7-0.7-0.5-0.6-0.8-0.70.10.9-0.7
Bone: trabecular tissue density1.52.12.91.3-1.5-1.4-1.41.6-1.4-1.3-1.41.6-1.7-1.4
Breakpoint value in progressive ratio session6.06.77.3-2.72.62.72.7-2.42.72.72.7-2.62.32.6
Distance traveled before self-admin0.40.50.90.8-0.7-0.6-0.70.5-0.7-0.7-0.60.6-0.5-1.0
Distance traveled after self-admin0.70.71.0-0.70.90.90.8-1.00.80.80.9-0.91.00.6
Delta time in closed arm before/after self-admin0.50.42.10.2-0.5-0.3-0.31.2-0.4-0.3-0.30.7-1.4-0.4
Delta time in open arm before/after self-admin1.41.31.61.2-1.2-1.2-1.31.0-1.2-1.2-1.21.1-0.9-1.0
Diff in mean of infusions in LGA sessions1.82.02.4-1.41.41.41.4-1.41.41.41.4-1.41.41.5
Extinction: sum of active levers before priming1.61.62.0-1.41.31.41.4-1.01.31.41.4-1.20.81.2
Active lever presses in extinction session 63.13.03.3-1.61.71.81.8-1.81.71.71.8-1.81.81.6
Delta distance traveled before/after self-admin1.71.82.2-1.31.41.31.3-1.41.41.31.3-1.41.41.5
Delta ambulatory time before/after self-admin1.71.92.2-1.31.41.31.4-1.51.41.31.3-1.41.51.4
Time in closed arm before self-admin1.01.21.61.3-1.1-1.2-1.10.6-1.1-1.2-1.21.0-0.4-1.2
Time in closed arm after self-admin0.00.00.0-0.20.10.00.2-0.00.10.10.0-0.10.00.2
Time in open arm before self-admin1.01.11.5-1.11.11.21.1-0.91.11.11.2-1.00.80.8
Time in open arm after self-admin0.70.70.90.9-0.9-0.7-0.90.9-0.9-0.9-0.80.9-0.9-0.9
Sum of active levers in priming session hrs 5-60.00.00.0-0.0-0.00.10.1-0.00.00.00.10.00.0-0.1
Time to tail flick, vehicle, before self-admin0.30.31.0-0.30.50.50.4-0.80.50.40.5-0.61.00.5
Time to tail flick, vehicle, after self-admin0.20.20.6-0.60.40.40.5-0.10.50.50.4-0.3-0.10.8
Time to tail flick, test, before self-admin0.10.10.5-0.10.20.20.3-0.60.20.10.1-0.40.70.1
Time to tail flick, test, after self-admin0.20.20.4-0.30.40.30.3-0.60.40.30.3-0.50.60.6
Delta time to tail flick, vehicle, before/after SA0.30.31.20.1-0.4-0.4-0.30.9-0.4-0.3-0.40.6-1.1-0.2
Delta time to tail flick, test, before/after SA0.20.20.4-0.60.40.50.4-0.20.50.50.5-0.40.10.7
Ambulatory time before self-admin0.30.40.70.7-0.6-0.5-0.60.5-0.6-0.6-0.50.6-0.4-0.8
Ambulatory time after self-admin0.40.40.6-0.50.60.70.6-0.70.60.60.7-0.70.70.4
Total heroin consumption2.02.42.6-1.51.61.61.6-1.61.61.51.6-1.61.61.5
Area under the delay curve2.52.63.21.7-1.6-1.6-1.81.6-1.7-1.7-1.61.6-1.5-1.5
Delay disc. indifference point, 0s delay8.39.010.73.3-3.1-3.2-3.12.4-3.1-3.2-3.22.9-2.1-3.2
Delay disc. indifference point, 16s delay0.10.20.30.4-0.4-0.4-0.50.4-0.4-0.4-0.40.4-0.3-0.3
Delay disc. indifference point, 2s delay6.37.07.72.8-2.7-2.8-2.72.5-2.7-2.8-2.82.6-2.3-2.6
Delay disc. indifference point, 24s delay0.70.60.90.8-0.8-0.7-0.90.9-0.8-0.8-0.70.8-0.9-0.6
Delay disc. indifference point, 4s delay1.31.41.91.3-1.1-1.2-1.41.0-1.2-1.3-1.21.1-0.9-1.1
Delay disc. indifference point, 8s delay1.11.21.71.0-1.0-1.0-1.11.3-1.1-1.0-1.01.1-1.3-1.0
Delay discount exponential model param2.22.42.9-1.61.51.51.7-1.51.61.61.5-1.51.51.4
Delay discount hyperbolic model param3.13.43.8-1.91.81.82.0-1.81.91.91.8-1.81.71.7
Fecal boli incidents, locomotor time 11.61.72.31.2-1.4-1.2-1.11.5-1.3-1.2-1.21.4-1.5-1.3
Change in fecal boli incidents, locomotor task0.20.10.4-0.20.50.30.4-0.50.30.20.3-0.50.60.1
Time >=10cm from walls, locomotor time 10.50.51.10.9-0.7-0.7-0.70.4-0.7-0.8-0.70.6-0.3-1.0
Bouts of movement, locomotor time 10.20.20.2-0.50.50.50.5-0.40.50.50.5-0.40.30.3
Total resting periods, locomotor time 10.20.30.3-0.50.60.50.5-0.50.50.50.5-0.50.50.4
Rest time, locomotor task time 10.20.20.3-0.40.40.40.4-0.60.40.40.4-0.50.60.4
Distance moved, locomotor task time 10.60.61.01.0-0.8-0.8-0.90.5-0.9-0.9-0.80.7-0.4-0.9
Vertical activity count, locomotor time 10.10.10.30.2-0.2-0.2-0.20.4-0.2-0.2-0.20.3-0.5-0.2
Time >=10cm from walls, locomotor time 21.11.21.81.0-1.0-0.9-1.01.3-1.0-1.0-0.91.1-1.3-1.2
Bouts of movement, locomotor time 20.30.31.0-0.30.50.40.3-0.90.50.40.4-0.61.00.5
Total resting periods, locomotor time 20.30.31.0-0.30.40.30.3-0.80.40.30.3-0.61.00.5
Rest time, locomotor task time 20.40.51.0-0.60.70.60.6-0.90.70.60.6-0.81.00.7
Distance moved, locomotor task time 20.60.71.20.7-0.9-0.8-0.81.0-0.8-0.8-0.80.9-1.1-0.8
Vertical activity count, locomotor time 20.50.61.50.5-0.7-0.6-0.51.1-0.7-0.6-0.60.9-1.2-0.6
Weight adjusted by age0.20.31.00.2-0.4-0.3-0.20.8-0.4-0.3-0.40.6-1.0-0.4
Seeking ratio, delayed vs. immediate footshock4.55.16.1-2.12.32.22.2-2.42.22.22.3-2.42.52.2
Locomotion in novel chamber0.40.50.8-0.80.70.80.7-0.50.70.80.9-0.60.40.6
Locomotion in novel chamber post-restriction0.91.01.3-1.01.11.01.1-0.91.01.01.0-1.00.81.1
Progressive ratio0.20.20.40.3-0.5-0.4-0.40.6-0.4-0.4-0.40.5-0.6-0.4
Food seeking constrained by brief footshock0.10.10.3-0.30.20.30.4-0.50.30.30.3-0.30.50.3
Seeking ratio, punishment vs. effort0.10.20.4-0.30.40.30.4-0.60.40.30.3-0.50.60.4
Run reversals in cocaine runway, females0.30.30.5-0.50.60.50.5-0.70.60.50.5-0.60.70.5
Run reversals in cocaine runway, males1.21.21.7-1.01.10.91.1-1.31.11.00.9-1.11.31.2
Latency to leave start box in cocaine runway0.70.81.9-0.60.90.90.6-1.20.80.70.9-1.01.40.5
Latency to leave start box in cocaine runway, F0.10.10.40.6-0.2-0.2-0.3-0.3-0.3-0.4-0.20.00.6-0.6
Latency to leave start box in cocaine runway, M3.33.24.0-1.91.82.01.7-1.51.91.92.0-1.71.31.8
Cd content in liver0.20.20.30.5-0.5-0.5-0.50.4-0.5-0.5-0.50.5-0.4-0.5
Co content in liver0.60.70.9-0.90.90.90.8-0.80.90.90.9-0.80.70.9
Cu content in liver0.20.20.40.6-0.5-0.5-0.60.1-0.5-0.6-0.50.30.1-0.6
Fe content in liver0.00.10.1-0.30.20.20.3-0.10.20.30.2-0.1-0.00.3
K content in liver0.10.10.20.4-0.2-0.2-0.4-0.2-0.2-0.3-0.20.10.4-0.3
Mg content in liver0.10.10.20.4-0.2-0.3-0.4-0.2-0.3-0.3-0.20.10.4-0.4
Mn content in liver0.60.62.6-0.30.70.50.4-1.30.60.40.5-0.91.60.5
Na content in liver1.21.31.71.3-1.2-1.2-1.20.8-1.2-1.2-1.21.1-0.6-1.2
Rb content in liver0.50.71.11.0-0.8-0.9-1.00.4-0.9-1.0-0.90.7-0.2-0.9
Se content in liver0.10.20.3-0.40.40.40.4-0.50.40.40.4-0.40.50.4
Sr content in liver0.10.10.2-0.40.20.30.40.10.20.30.3-0.1-0.30.3
Zn content in liver2.52.73.6-1.91.71.91.7-1.11.71.81.9-1.50.81.8