Hub : Genes

Stx5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS ENSRNOT00000025664 0.03 0.02 1.6e-03 0.01 0.01 0.01 0.01 1.4e-02 9.9e-03 9.7e-03 1.9e-02
2 Adipose alternative TSS ENSRNOT00000095404 0.03 0.02 1.8e-03 0.01 0.01 0.01 0.01 1.1e-02 1.2e-02 1.1e-02 2.4e-02
3 Adipose gene expression ENSRNOG00000018847 0.06 0.04 2.1e-06 0.05 0.04 0.03 0.03 5.0e-06 7.1e-05 5.7e-04 9.8e-05
4 Adipose mRNA stability ENSRNOG00000018847 0.17 0.07 0.0e+00 0.11 0.16 0.16 0.16 2.8e-12 7.1e-17 3.5e-17 7.3e-17
5 Brain mRNA stability ENSRNOG00000018847 0.09 0.05 1.6e-07 0.05 0.08 0.07 0.07 2.0e-05 1.5e-07 1.8e-07 2.2e-07
6 Eye mRNA stability ENSRNOG00000018847 0.28 0.15 6.7e-03 0.04 0.09 0.08 0.07 7.9e-02 1.7e-02 2.5e-02 3.5e-02
7 NAcc mRNA stability ENSRNOG00000018847 0.18 0.1 2.9e-13 0.19 0.17 0.16 0.17 4.6e-14 1.7e-12 6.0e-12 7.5e-13
8 PL mRNA stability ENSRNOG00000018847 0.12 0.07 1.9e-09 0.1 0.12 0.13 0.13 6.2e-08 1.3e-09 2.7e-10 6.2e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail2.47.814.52.8-2.62.5-3.80.8-3.5-2.7-2.6
BMI without tail1.02.12.71.6-1.61.4-1.61.1-1.5-1.5-1.2
Body weight3.514.817.54.2-4.13.8-4.02.7-3.8-4.2-3.8
Epididymis fat weight0.20.61.4-0.80.9-1.0-0.2-1.20.10.50.7
Glucose2.43.75.4-2.12.1-2.31.1-2.11.32.02.0
Heart weight0.71.12.1-0.90.9-1.30.8-0.41.01.21.5
Left kidney weight0.10.20.60.2-0.20.1-0.8-0.7-0.7-0.4-0.4
Right kidney weight0.30.71.70.5-0.40.4-1.2-0.9-1.3-0.7-0.8
Tail length0.82.65.41.8-1.91.6-0.62.3-0.6-1.8-1.4
Length with tail2.27.910.13.1-3.12.8-2.32.5-2.3-3.2-2.9
Length without tail1.94.15.22.2-2.12.0-2.11.3-2.0-2.3-2.2
Liver weight, left0.30.50.8-0.60.6-0.90.8-0.10.90.70.7
Liver weight, right0.00.00.10.2-0.2-0.2-0.40.2-0.1-0.10.1
Parametrial fat weight1.32.65.2-1.71.8-1.70.6-2.30.61.81.6
Retroperitoneal fat weight2.06.79.5-2.72.8-3.11.6-2.51.92.82.8
Intraocular pressure0.10.10.2-0.40.4-0.40.4-0.30.40.10.2
Extensor digitorum longus weight6.325.130.65.3-5.25.0-5.13.5-4.9-5.5-5.2
Soleus weight2.57.28.7-2.92.9-2.82.4-1.82.62.92.9
Tibialis anterior weight9.532.738.76.1-6.16.1-5.33.8-5.4-6.2-6.2
Tibia length1.74.78.01.8-1.72.3-2.6-0.5-2.8-2.1-2.7
Number of licking bursts0.00.00.0-0.00.0-0.1-0.1-0.1-0.0-0.1-0.1
Food consumed during 24 hour testing period0.10.10.2-0.40.4-0.4-0.0-0.50.20.10.1
Times rat made contact with spout0.20.31.30.4-0.50.40.21.10.3-0.3-0.1
Mean time between licks in bursts0.81.14.61.2-1.30.7-0.22.2-0.1-0.8-0.3
Mean num. licks in bursts0.10.10.3-0.0-0.0-0.10.50.60.60.20.3
Std. dev. time between licks in bursts0.40.51.1-0.20.1-0.50.81.00.90.40.8
Water consumed over 24 hours0.50.51.20.8-0.80.6-0.31.1-0.2-0.9-0.7
Indifference point 0 sec0.50.81.10.9-0.91.0-1.00.7-0.8-0.9-1.0
Indifference point AUC2.32.74.41.5-1.51.6-1.70.1-1.9-1.8-2.1
Indifference point function ln k3.65.18.7-2.12.1-2.32.2-0.02.52.62.9
Indifference point function log k3.65.18.7-2.12.1-2.32.2-0.02.52.62.9
Delay discounting total patch changes 0 sec0.50.81.21.0-1.00.9-0.71.1-0.5-0.9-0.9
Delay discounting total patch changes 12 sec6.08.010.53.1-3.13.1-2.61.7-2.7-2.9-3.2
Delay discounting total patch changes 18 sec0.50.61.00.8-0.90.9-0.70.3-0.7-0.8-1.0
Delay discounting total patch changes 24 sec6.98.610.23.2-3.23.0-3.02.0-2.9-3.1-2.9
Delay discounting total patch changes 6 sec1.11.72.11.5-1.41.3-1.41.0-1.2-1.3-1.3
Delay discounting time to switch 0 sec0.60.92.10.6-0.60.9-1.4-0.7-1.4-0.7-0.8
Delay discounting water rate 0 sec0.50.81.5-0.80.8-0.91.10.21.20.90.8
Delay discounting water rate 12 sec2.03.05.3-1.51.4-1.82.10.62.31.72.0
Delay discounting water rate 18 sec0.91.22.3-0.70.7-1.11.10.91.41.11.5
Delay discounting water rate 24 sec1.41.93.0-1.31.2-1.41.60.11.71.51.6
Delay discounting water rate 6 sec1.42.03.8-1.11.0-1.41.80.62.01.31.7
Locomotor activity1.01.73.5-0.80.8-1.21.70.91.91.31.4
Locomotor testing distance1.22.03.9-0.90.8-1.31.71.12.01.41.7
Locomotor testing rearing1.01.63.0-1.11.0-1.31.50.41.71.31.5
Light reinforcement 10.10.20.4-0.50.4-0.30.60.10.70.10.2
Light reinforcement 20.60.84.2-0.70.8-0.4-0.5-2.0-0.60.1-0.2
Reaction time number correct0.50.81.90.9-1.00.6-0.61.4-0.3-1.1-0.7
Reaction time mean minus median0.40.51.10.4-0.50.6-0.6-0.8-0.9-0.7-1.0
Reaction time mean minus median AUC0.10.10.30.2-0.30.20.1-0.2-0.1-0.4-0.5
Reaction time num false alarms0.60.81.9-0.20.1-0.41.31.31.40.70.8
Reaction time num false alarms AUC0.50.73.30.4-0.50.11.01.81.00.20.2
Reaction time trials correct on left0.50.81.90.9-1.00.6-0.61.4-0.3-1.1-0.7
Reaction time trials on left0.60.82.10.9-1.00.6-0.51.4-0.3-1.1-0.7
Reaction time mean0.10.20.8-0.40.3-0.00.2-0.9-0.10.3-0.1
Reaction time mean AUC0.20.21.1-0.50.5-0.20.2-1.00.00.30.0
Median of all reaction times0.10.10.4-0.10.10.2-0.1-0.6-0.30.1-0.1
Reaction time omissions0.10.10.30.3-0.30.20.50.50.3-0.0-0.2
Reaction time false alarm rate0.40.51.3-0.30.2-0.31.10.71.10.80.7
Reaction time premature initiation rate3.85.16.72.5-2.52.3-1.92.6-1.8-2.5-1.8
Reaction time premature initiations4.86.911.12.9-3.02.5-2.03.3-1.7-2.9-2.1
Std. dev. reaction times0.10.20.7-0.40.3-0.20.6-0.80.20.3-0.1
Reaction time trials completed0.60.82.10.9-1.00.6-0.51.4-0.3-1.1-0.7
Reaction time trials AUC0.40.61.80.8-0.90.5-0.51.4-0.2-1.0-0.6
Social response proportion0.20.20.40.4-0.40.3-0.30.5-0.2-0.6-0.7
Social responses0.20.20.90.3-0.30.10.30.90.4-0.4-0.4
Social time0.20.20.60.1-0.1-0.20.60.80.7-0.10.1
Conditioned locomotion0.50.60.91.0-1.00.8-0.70.7-0.7-0.7-0.7
Cocaine response after cond. corrected0.80.91.9-0.70.7-0.81.00.21.11.21.4
Cocaine response after cond. not corrected0.60.61.2-0.70.7-0.60.80.10.81.01.1
Cocaine response before conditioning0.40.51.10.2-0.20.7-0.7-0.2-0.7-0.9-1.1
Saline control response2.22.93.61.9-1.91.9-1.31.9-1.2-1.9-1.5
Condit. Reinf. active minus inactive responses0.30.41.5-0.80.8-0.50.2-1.20.20.50.2
Condit. Reinf. active-inactive response ratio1.01.15.2-1.01.1-0.6-0.2-2.3-0.20.80.3
Condit. Reinf. active responses0.00.00.1-0.10.10.1-0.1-0.2-0.0-0.2-0.3
Condit. Reinf. inactive responses0.30.42.30.4-0.40.30.31.50.4-0.5-0.2
Condit. Reinf. lever presses1.01.42.40.9-0.91.1-1.40.1-1.3-1.3-1.6
Condit. Reinf. lever reinforcers received0.10.10.40.2-0.20.4-0.3-0.0-0.3-0.5-0.7
Pavlov. Cond. lever latency0.60.81.6-0.60.6-0.81.20.01.10.91.2
Pavlov. Cond. magazine entry latency4.34.96.72.2-2.22.6-2.01.4-2.1-2.4-2.6
Pavlov. Cond. change in total contacts1.62.23.91.1-1.11.5-1.8-0.1-1.8-1.6-2.0
Pavlov. Cond. index score2.83.65.81.6-1.62.0-2.20.5-2.1-2.1-2.4
Pavlov. Cond. latency score2.63.35.31.5-1.51.9-2.10.3-2.1-1.9-2.3
Pavlov. Cond. lever contacts0.40.61.40.5-0.50.8-0.80.2-0.7-0.8-1.2
Pavlov. Cond. magazine entry number7.08.611.5-2.92.9-3.32.9-1.53.03.23.4
Pavlov. Cond. intertrial magazine entries1.72.12.4-1.51.5-1.51.5-1.21.41.51.5
Pavlov. Cond. lever-magazine prob. diff.3.14.06.11.8-1.72.2-2.20.6-2.2-2.2-2.5
Pavlov. Cond. response bias1.62.33.81.3-1.41.6-1.60.6-1.5-1.7-1.9
Conditioned reinforcement - actives2.22.24.1-1.61.6-1.31.1-2.00.91.61.2
Conditioned reinforcement - inactives1.01.13.9-1.11.2-0.80.2-2.00.00.90.7
Conditioned locomotion1.92.34.1-1.71.7-1.50.8-2.00.71.91.5
Intermittent access intake day 1-15 change1.31.32.2-1.31.3-1.11.1-1.50.91.00.6
Intermittent access intake escalation0.70.71.4-1.01.0-0.80.9-1.20.70.80.3
Intermittent access intake escalation 20.10.10.6-0.20.20.10.1-0.7-0.10.0-0.5
Intermitt. access day 1 inactive lever presses1.71.92.7-1.61.6-1.31.0-1.60.91.41.3
Intermitt. access day 15 inactive lever presses0.50.51.4-0.00.10.1-1.0-1.2-1.1-0.5-0.5
Intermitt. access escalation Index0.30.20.7-0.30.3-0.60.30.30.50.40.8
Intermittent access day 1 total infusions0.91.03.6-0.91.0-0.7-0.5-1.9-0.41.00.9
Intermittent access day 15 total infusions3.03.48.1-2.02.1-1.70.9-2.80.72.01.5
Intermittent access terminal intake (last 3 days)1.01.15.7-0.90.9-0.4-0.5-2.4-0.60.80.3
Intermittent access total infusions1.01.24.8-1.01.1-0.7-0.2-2.2-0.31.00.7
Intermittent access day 1 locomotion0.40.41.0-0.20.3-0.1-0.9-1.0-0.70.50.6
Intermittent access day 15 total locomotion0.50.52.4-0.40.5-0.2-0.5-1.5-0.70.60.2
Intermittent access total locomotion1.01.24.9-0.30.50.0-1.3-2.2-1.50.40.1
Intermittent access standard deviation1.31.41.8-1.31.3-1.01.2-1.31.01.40.9
Cocaine induced anxiety0.40.41.10.5-0.50.6-0.7-0.2-0.8-0.5-1.1
Post-drug Anxiety0.70.81.80.7-0.70.9-0.9-0.2-1.1-0.9-1.4
Baseline Anxiety0.91.01.51.1-1.11.0-0.71.2-0.7-1.1-0.8
Lifetime Intake0.80.92.9-0.91.0-0.7-0.0-1.7-0.01.00.9
Incentive Sensitization - Responses0.30.30.90.2-0.10.3-0.8-0.9-0.9-0.3-0.4
Incentive Sensitization - Breakpoint0.30.31.00.00.00.2-0.8-1.0-0.9-0.2-0.3
Progressive ratio test 1 active lever presses1.92.03.0-1.51.5-1.11.2-1.61.01.71.6
Progressive ratio test 1 breakpoint2.22.33.3-1.61.6-1.21.3-1.61.11.81.7
Progressive ratio test 1 inactive lever presses0.10.10.10.3-0.20.4-0.30.2-0.3-0.10.2
Progressive ratio test 2 active lever presses1.71.84.8-1.41.5-1.00.6-2.20.41.51.2
Progressive ratio test 2 breakpoint2.62.95.6-1.91.9-1.51.1-2.40.91.91.6
Progressive ratio test 2 inactive lever presses0.80.94.0-0.91.0-0.5-0.1-2.0-0.30.80.5
Total sessions with >9 infusions1.41.62.6-1.31.3-1.30.7-1.30.71.51.6
Short access day 1 total inactive lever presses0.70.81.6-0.91.0-0.80.4-1.00.41.11.3
Short access day 10 total inactive lever presses2.32.63.4-1.61.6-1.81.7-0.51.81.71.8
Short access day 1 total infusions0.70.71.3-0.80.9-0.80.4-0.90.51.01.2
Short access day 10 total infusions0.40.41.5-0.40.5-0.3-0.6-1.2-0.50.60.7
Short access total infusions0.30.40.8-0.50.6-0.5-0.1-0.80.00.80.9
Short access day 1 locomotion0.20.20.90.3-0.20.2-1.0-0.3-0.8-0.00.2
Short access day 10 total locomotion0.20.20.60.1-0.00.1-0.8-0.6-0.80.00.1
Short access total locomotion0.40.41.30.5-0.40.5-1.1-0.3-1.1-0.2-0.1
Compulsive drug intake1.71.77.41.3-1.30.7-0.12.70.3-1.3-0.5
One hour access (0.3 mA shock)3.44.06.9-2.22.3-1.91.3-2.61.22.11.9
One hour access (shock baseline)4.95.613.4-2.72.7-2.01.4-3.71.12.61.8
Number of responses in last shaping day0.10.10.40.2-0.20.00.20.70.40.20.2
Context. condit. distance diff. score0.30.40.9-0.60.6-0.60.4-0.20.41.01.0
Locomotion velocity, session 10.10.10.50.1-0.10.10.20.70.20.30.4
Locomotion distance, session 10.40.60.80.8-0.70.9-0.80.9-0.7-0.6-0.4
Locomotion velocity, session 22.73.23.91.9-1.92.0-1.81.1-1.7-1.8-1.9
Locomotion distance, session 20.20.30.80.7-0.70.6-0.20.9-0.2-0.4-0.3
Locomotion velocity, session 30.40.41.40.6-0.50.5-1.20.1-0.9-0.5-0.3
Locomotion distance, session 30.10.10.30.2-0.20.1-0.20.60.0-0.3-0.1
Stereotopy head waving bouts, day 30.20.20.7-0.10.2-0.1-0.5-0.8-0.50.60.5
Stereotopy head waving duration, day 30.10.20.5-0.20.3-0.2-0.1-0.5-0.10.70.6
Locomotion velocity, session 70.10.10.3-0.10.1-0.1-0.3-0.5-0.30.20.1
Locomotion distance, session 70.10.10.3-0.10.2-0.40.20.10.20.50.6
Stereotopy head waving bouts, day 70.30.30.80.2-0.10.5-0.8-0.8-0.9-0.2-0.4
Stereotopy head waving duration, day 71.82.23.21.4-1.41.6-1.80.4-1.8-1.5-1.6
Locomotion velocity, session 80.20.30.7-0.00.0-0.00.70.80.70.50.6
Locomotion distance, session 80.20.30.6-0.50.5-0.4-0.0-0.60.10.80.7
Degree of sensitization distance0.10.20.4-0.10.2-0.3-0.5-0.6-0.40.40.4
Degree of sensitization stereotypy1.01.11.90.8-0.71.2-1.3-0.2-1.4-1.0-1.2
Condit. Reinf. active minus inactive responses0.91.01.41.0-1.01.2-1.00.6-1.1-1.1-1.0
Condit. Reinf. active-inactive response ratio0.30.30.60.6-0.60.7-0.30.8-0.3-0.6-0.5
Condit. Reinf. active responses1.01.22.30.9-0.91.2-1.4-0.1-1.5-1.1-1.2
Condit. Reinf. inactive responses0.30.41.5-0.10.20.0-0.8-1.2-0.8-0.1-0.3
Incentive salience index mean1.31.52.21.2-1.11.3-1.50.6-1.5-1.3-1.2
Condit. Reinf. lever presses0.81.12.00.9-0.81.0-1.40.3-1.4-1.1-1.0
Time in familiar zone, hab. session 10.10.10.20.2-0.20.2-0.50.2-0.4-0.3-0.2
Time in novel zone, hab. session 11.51.52.2-1.21.1-1.31.4-0.21.51.21.4
Total zone transitions, hab. session 10.20.30.40.6-0.60.7-0.30.5-0.4-0.5-0.6
Total locomotion distance, hab. session 10.10.20.7-0.20.3-0.1-0.3-0.9-0.30.40.2
Locomotion velocity, hab. session 10.10.20.50.4-0.30.5-0.6-0.3-0.7-0.2-0.4
Time in familiar zone, hab. session 20.60.61.5-0.50.4-0.81.10.81.20.40.8
Time in novel zone, hab. session 20.70.71.40.7-0.70.8-1.2-0.1-1.1-0.6-0.8
Total zone transitions, hab. session 21.41.81.91.4-1.41.4-1.41.3-1.2-1.4-1.2
Total locomotion distance, hab. session 20.10.20.40.4-0.40.4-0.60.2-0.5-0.3-0.3
Locomotion velocity, hab. session 20.10.10.40.2-0.20.3-0.6-0.2-0.6-0.2-0.2
Novel to familiar place preference ratio2.32.53.51.6-1.51.5-1.80.3-1.8-1.7-1.9
Novelty place preference1.51.52.31.2-1.21.1-1.50.0-1.4-1.3-1.5
Time in novel zone, NPP test1.51.62.21.3-1.21.1-1.50.2-1.5-1.4-1.5
Total zone transitions, NPP test1.11.52.21.3-1.31.5-1.01.2-1.0-1.2-1.2
Total locomotion distance, NPP test0.10.10.20.4-0.30.5-0.20.4-0.2-0.1-0.1
Locomotion velocity, NPP test0.00.00.10.2-0.20.4-0.00.3-0.10.0-0.0
Pavlov. Cond. lever latency1.31.62.8-1.11.1-1.31.7-0.21.71.21.3
Pavlov. Cond. magazine entry latency1.21.63.01.0-0.91.2-1.7-0.3-1.7-1.2-1.3
Pavlov. Cond. change in total contacts0.60.71.50.3-0.20.7-1.2-1.0-1.2-0.5-0.9
Pavlov. Cond. index score0.60.81.50.7-0.71.0-1.2-0.1-1.2-0.9-1.0
Pavlov. Cond. latency score0.50.71.20.6-0.60.9-1.1-0.0-1.1-0.8-0.9
Pavlov. Cond. lever contacts0.30.30.70.5-0.40.5-0.9-0.0-0.8-0.5-0.6
Pavlov. Cond. magazine entry number0.70.81.4-0.70.7-1.11.00.21.20.91.2
Pavlov. Cond. intertrial magazine entries0.00.10.20.0-0.00.30.1-0.3-0.1-0.2-0.4
Pavlov. Cond. lever-magazine prob. diff.0.81.11.90.8-0.81.1-1.3-0.2-1.4-1.0-1.2
Pavlov. Cond. response bias0.81.01.70.8-0.71.0-1.2-0.2-1.3-1.0-1.1
Bone: apparent density0.30.51.50.5-0.40.5-1.2-0.2-1.1-0.6-0.5
Bone surface2.03.67.11.6-1.51.7-2.7-0.1-2.5-1.8-2.0
Bone volume1.01.84.30.9-0.81.0-2.1-0.7-2.0-1.1-1.4
Bone: connectivity density1.62.54.51.5-1.41.5-2.10.6-2.0-1.6-1.4
Bone: cortical apparent density0.30.50.90.7-0.80.9-0.10.9-0.3-0.7-0.6
Bone: cortical area1.01.52.31.0-1.01.2-1.50.0-1.5-1.3-1.5
Bone: cortical porosity0.10.10.3-0.10.1-0.10.6-0.10.40.40.1
Bone: cortical porosity0.10.10.20.2-0.30.20.40.40.30.0-0.1
Bone: cortical thickness2.84.66.32.3-2.42.4-1.22.5-1.3-2.4-2.2
Bone: cortical thickness0.60.72.40.8-0.90.80.01.50.0-0.7-0.5
Bone: cortical tissue density0.40.61.10.8-0.91.0-0.11.0-0.3-0.8-0.7
Bone: elastic displacement0.80.91.9-0.60.6-0.81.40.61.40.81.1
Bone: elastic work0.81.03.11.2-1.21.0-0.41.7-0.2-0.9-0.6
Bone: endosteal estimation1.12.47.4-1.61.7-1.6-0.4-2.7-0.11.51.2
Bone: endosteal perimeter1.83.813.1-2.02.2-1.9-0.3-3.6-0.11.81.2
Bone: final force2.13.45.31.7-1.71.9-2.30.6-2.2-1.9-1.9
Bone: final moment2.03.35.21.7-1.71.8-2.30.6-2.2-1.9-1.9
Bone: marrow area1.32.77.6-1.71.8-1.8-0.3-2.80.01.71.4
Bone: maximum diameter0.40.81.80.3-0.20.6-1.3-1.2-1.3-0.5-1.0
Bone: maximum force3.05.310.32.0-1.92.1-3.20.0-3.0-2.2-2.4
Bone: maximum moment2.84.99.51.9-1.82.0-3.10.1-2.9-2.2-2.3
Bone: minimum diameter0.71.35.2-1.11.2-1.0-0.8-2.3-0.50.80.6
Bone: periosteal estimation0.40.93.3-0.30.4-0.1-1.4-1.8-1.20.0-0.3
Bone: periosteal perimeter0.30.52.2-0.20.3-0.0-1.0-1.5-0.9-0.1-0.5
Bone: post-yield work1.21.67.0-0.60.8-0.5-1.6-2.6-1.40.4-0.1
Bone: stiffness1.11.73.30.9-0.91.1-1.8-0.5-1.8-1.3-1.5
Bone: tissue strength0.20.20.5-0.60.6-0.70.4-0.10.50.10.4
Bone: trabecular number0.81.33.20.9-0.80.9-1.8-0.1-1.7-1.0-0.9
Bone: trabecular spacing0.60.71.9-0.50.4-0.61.40.81.40.50.7
Bone: trabecular thickness0.30.41.5-0.70.7-0.60.0-1.2-0.10.60.4
Bone: trabecular tissue density4.56.28.0-2.62.6-2.42.8-1.42.62.72.6
Breakpoint value in progressive ratio session1.82.03.41.5-1.51.6-1.00.8-1.2-1.5-1.8
Distance traveled before self-admin2.32.53.71.5-1.41.6-1.70.4-1.8-1.8-1.9
Distance traveled after self-admin0.30.30.60.4-0.50.3-0.60.1-0.5-0.8-0.7
Delta time in closed arm before/after self-admin1.51.54.71.5-1.51.0-0.72.2-0.5-1.0-0.6
Delta time in open arm before/after self-admin1.71.72.51.1-1.11.5-1.4-0.2-1.6-1.3-1.6
Diff in mean of infusions in LGA sessions1.51.62.31.4-1.51.5-0.61.4-0.8-1.3-1.3
Extinction: sum of active levers before priming3.63.64.42.0-2.02.0-1.91.1-1.9-2.1-2.1
Active lever presses in extinction session 62.42.33.61.4-1.51.8-1.30.6-1.6-1.6-1.9
Delta distance traveled before/after self-admin0.70.81.3-0.70.7-1.11.00.11.10.81.1
Delta ambulatory time before/after self-admin1.21.32.2-0.90.9-1.31.30.21.51.11.3
Time in closed arm before self-admin0.20.21.0-0.30.3-0.1-0.4-1.0-0.4-0.1-0.2
Time in closed arm after self-admin0.50.50.9-0.60.6-0.90.6-0.10.80.70.9
Time in open arm before self-admin1.51.63.3-0.70.6-1.11.61.21.81.11.5
Time in open arm after self-admin0.10.10.50.3-0.30.30.40.70.40.0-0.1
Sum of active levers in priming session hrs 5-61.21.12.80.7-0.81.2-0.9-0.4-1.2-1.2-1.7
Time to tail flick, vehicle, before self-admin0.90.92.10.7-0.60.8-1.4-0.5-1.4-0.8-0.8
Time to tail flick, vehicle, after self-admin0.40.40.60.7-0.70.6-0.70.8-0.6-0.6-0.4
Time to tail flick, test, before self-admin0.40.41.10.8-0.70.3-1.10.4-0.8-0.5-0.3
Time to tail flick, test, after self-admin0.10.10.1-0.30.3-0.30.3-0.20.30.10.2
Delta time to tail flick, vehicle, before/after SA0.10.10.50.1-0.1-0.00.30.70.30.10.1
Delta time to tail flick, test, before/after SA0.20.10.6-0.30.3-0.00.8-0.10.50.2-0.1
Ambulatory time before self-admin2.02.13.11.2-1.21.6-1.50.0-1.8-1.6-1.6
Ambulatory time after self-admin0.30.40.70.3-0.30.3-0.9-0.5-0.8-0.6-0.7
Total heroin consumption3.33.95.52.2-2.22.2-1.31.9-1.4-2.1-2.4
Area under the delay curve0.00.00.10.2-0.2-0.0-0.30.2-0.2-0.10.2
Delay disc. indifference point, 0s delay0.20.20.7-0.30.4-0.50.1-0.00.30.50.8
Delay disc. indifference point, 16s delay0.20.20.70.3-0.20.2-0.8-0.4-0.7-0.4-0.2
Delay disc. indifference point, 2s delay0.20.20.5-0.50.5-0.5-0.1-0.7-0.00.40.5
Delay disc. indifference point, 24s delay0.20.20.70.5-0.50.2-0.10.80.0-0.2-0.1
Delay disc. indifference point, 4s delay0.30.41.00.8-0.80.5-0.51.0-0.3-0.40.0
Delay disc. indifference point, 8s delay0.40.40.7-0.40.4-0.70.70.30.80.60.8
Delay discount exponential model param0.00.00.1-0.20.20.00.3-0.20.20.1-0.2
Delay discount hyperbolic model param0.00.00.1-0.20.2-0.00.3-0.20.20.1-0.1
Fecal boli incidents, locomotor time 10.40.52.5-0.70.7-0.4-0.1-1.6-0.20.30.0
Change in fecal boli incidents, locomotor task0.80.81.6-0.50.5-0.91.00.51.11.01.3
Time >=10cm from walls, locomotor time 12.52.56.9-1.81.9-1.50.5-2.60.31.61.2
Bouts of movement, locomotor time 10.20.20.40.2-0.30.60.70.60.4-0.1-0.5
Total resting periods, locomotor time 10.10.10.40.2-0.30.60.30.30.1-0.2-0.5
Rest time, locomotor task time 11.31.42.0-1.21.1-1.41.2-0.71.31.01.2
Distance moved, locomotor task time 10.20.20.50.4-0.40.6-0.60.2-0.7-0.3-0.5
Vertical activity count, locomotor time 10.60.71.0-0.90.9-0.80.7-0.60.71.00.8
Time >=10cm from walls, locomotor time 20.20.21.0-0.50.5-0.20.2-1.00.00.4-0.0
Bouts of movement, locomotor time 21.31.42.01.3-1.31.3-0.91.1-0.9-1.4-1.3
Total resting periods, locomotor time 20.70.71.10.9-0.90.8-0.70.7-0.6-1.1-1.0
Rest time, locomotor task time 23.03.55.2-1.91.9-2.31.6-1.41.81.91.9
Distance moved, locomotor task time 20.40.41.00.6-0.71.0-0.20.8-0.4-0.5-0.8
Vertical activity count, locomotor time 20.40.41.2-0.0-0.0-0.11.01.10.90.30.3
Weight adjusted by age1.71.92.81.4-1.31.4-1.60.3-1.7-1.5-1.5
Seeking ratio, delayed vs. immediate footshock0.00.00.10.2-0.2-0.0-0.20.2-0.1-0.3-0.1
Locomotion in novel chamber2.12.76.5-1.81.9-1.50.7-2.60.51.51.5
Locomotion in novel chamber post-restriction2.53.03.6-1.81.8-1.71.7-1.61.51.91.7
Progressive ratio0.10.20.4-0.00.0-0.0-0.6-0.6-0.5-0.4-0.3
Food seeking constrained by brief footshock0.20.20.4-0.30.2-0.50.60.50.60.20.6
Seeking ratio, punishment vs. effort0.30.41.0-0.10.0-0.20.91.00.90.50.7
Run reversals in cocaine runway, females0.90.91.81.1-1.00.8-1.01.4-0.7-0.7-0.4
Run reversals in cocaine runway, males0.60.60.9-0.70.7-0.80.9-0.20.90.80.8
Latency to leave start box in cocaine runway0.30.30.9-0.50.6-0.6-0.2-0.9-0.00.60.4
Latency to leave start box in cocaine runway, F0.10.10.20.1-0.10.1-0.4-0.3-0.3-0.1-0.3
Latency to leave start box in cocaine runway, M3.02.83.6-1.81.8-1.81.3-1.51.41.91.8
Cd content in liver1.21.41.9-1.31.3-1.10.8-1.30.81.41.2
Co content in liver2.83.26.8-1.41.3-1.52.60.72.61.71.9
Cu content in liver0.20.31.20.6-0.60.4-0.01.10.0-0.4-0.2
Fe content in liver0.00.00.2-0.10.10.1-0.1-0.5-0.20.2-0.0
K content in liver1.31.32.50.9-0.91.0-1.60.0-1.5-1.2-1.3
Mg content in liver0.60.61.70.5-0.40.5-1.3-0.3-1.2-0.6-0.7
Mn content in liver2.22.64.01.5-1.51.5-1.80.6-1.7-1.8-2.0
Na content in liver0.80.81.40.6-0.60.9-1.1-0.2-1.2-1.0-1.2
Rb content in liver1.41.72.7-1.41.4-1.51.1-0.61.21.41.6
Se content in liver0.70.81.60.3-0.20.5-1.2-1.1-1.2-0.6-1.2
Sr content in liver5.65.16.32.4-2.52.5-1.91.4-2.1-2.5-2.5
Zn content in liver4.14.65.82.2-2.22.4-2.20.9-2.3-2.2-2.3