Hub : Genes

Htr7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000025493 0.04 0.03 3.9e-03 0.01 0 -0 0 3.2e-02 2.4e-01 6.1e-01 3.3e-01
2 Adipose gene expression ENSRNOG00000018827 0.09 0.05 3.3e-06 0.04 0.05 0.04 0.04 8.3e-06 7.8e-06 3.2e-05 8.9e-06
3 BLA gene expression ENSRNOG00000018827 0.06 0.04 3.4e-03 0.02 0.03 0.03 0.02 2.6e-02 6.4e-03 9.7e-03 4.0e-02
4 BLA isoform ratio ENSRNOT00000025450 0.08 0.05 1.1e-03 0.06 0.05 0.02 0.04 6.9e-04 1.6e-03 1.9e-02 5.1e-03
5 BLA isoform ratio ENSRNOT00000025493 0.06 0.04 7.3e-03 0.04 0.03 0.01 0.01 5.0e-03 1.7e-02 1.2e-01 7.0e-02
6 Brain gene expression ENSRNOG00000018827 0.13 0.08 4.3e-06 0.05 0.06 0.05 0.05 8.7e-06 1.4e-06 1.2e-05 3.4e-05
7 IL gene expression ENSRNOG00000018827 0.18 0.1 2.7e-04 0.05 0.1 0.14 0.13 2.5e-02 2.4e-03 3.6e-04 5.7e-04
8 LHb gene expression ENSRNOG00000018827 0.18 0.11 2.4e-04 0.14 0.11 0.12 0.08 2.7e-04 1.6e-03 7.7e-04 5.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.10.20.7-0.00.80.1-0.10.2-0.20.6-0.6
BMI without tail0.71.53.6-0.1-0.41.21.7-1.2-1.9-0.1-1.5
Body weight1.98.213.0-1.6-3.43.53.6-3.5-2.5-2.1-1.9
Epididymis fat weight0.71.73.9-1.3-2.01.31.2-1.0-0.5-1.8-0.0
Glucose0.20.41.1-0.4-0.1-0.4-0.90.41.0-0.40.7
Heart weight0.30.40.70.3-0.3-0.7-0.60.50.7-0.80.8
Left kidney weight1.23.69.3-2.4-3.11.71.5-1.5-0.4-2.40.2
Right kidney weight1.85.214.4-2.6-3.81.31.4-1.30.0-3.71.1
Tail length4.112.422.6-1.8-3.74.04.7-4.3-3.9-1.9-2.6
Length with tail5.018.530.9-2.3-5.64.95.4-5.4-3.6-3.3-2.2
Length without tail2.45.211.5-2.0-3.42.72.4-2.8-0.8-2.1-0.6
Liver weight, left1.82.86.4-1.3-2.52.21.6-2.2-0.6-1.3-0.6
Liver weight, right2.33.87.3-2.3-2.72.22.0-2.0-1.1-1.9-0.5
Parametrial fat weight1.22.33.6-1.9-1.71.81.6-1.6-1.1-1.2-0.7
Retroperitoneal fat weight0.20.61.1-0.6-1.10.90.7-0.9-0.3-1.0-0.3
Intraocular pressure0.20.20.60.7-0.80.30.2-0.5-0.1-0.5-0.0
Extensor digitorum longus weight0.52.04.2-2.1-1.02.01.6-1.4-0.9-0.5-1.2
Soleus weight0.61.74.01.61.40.50.7-0.6-1.02.0-1.6
Tibialis anterior weight0.93.26.4-1.9-0.62.52.1-1.9-1.70.2-2.1
Tibia length0.41.02.4-0.2-1.61.01.2-1.2-0.8-1.0-0.2
Number of licking bursts2.93.47.2-0.9-2.0-1.1-1.11.12.1-2.72.7
Food consumed during 24 hour testing period0.70.92.9-0.5-1.5-0.10.0-0.10.7-1.71.0
Times rat made contact with spout1.21.42.7-0.5-1.11.41.6-1.6-1.2-0.4-1.0
Mean time between licks in bursts1.82.54.50.20.8-2.0-2.12.11.8-0.01.7
Mean num. licks in bursts3.54.29.50.51.41.81.8-1.7-2.62.4-3.1
Std. dev. time between licks in bursts2.93.55.8-0.10.5-2.3-2.32.42.3-0.72.2
Water consumed over 24 hours0.60.71.7-1.2-1.30.70.8-0.70.0-1.10.1
Indifference point 0 sec0.91.54.4-0.9-2.10.60.9-1.2-0.5-1.90.5
Indifference point AUC1.71.94.1-1.0-1.41.11.7-1.5-2.0-1.2-0.7
Indifference point function ln k0.30.51.90.30.6-0.1-0.70.71.40.70.2
Indifference point function log k0.30.51.90.30.6-0.1-0.70.71.40.70.2
Delay discounting total patch changes 0 sec0.91.44.2-0.8-2.00.61.0-1.2-0.6-1.80.4
Delay discounting total patch changes 12 sec0.50.71.6-0.4-1.10.00.9-0.8-1.1-1.30.1
Delay discounting total patch changes 18 sec1.01.32.2-0.6-1.50.81.4-1.4-1.3-1.3-0.3
Delay discounting total patch changes 24 sec2.02.56.6-1.4-2.61.21.4-1.7-1.0-2.20.1
Delay discounting total patch changes 6 sec1.31.94.2-0.7-2.00.51.4-1.4-1.5-2.00.2
Delay discounting time to switch 0 sec2.53.87.40.40.6-2.2-2.42.62.7-0.42.2
Delay discounting water rate 0 sec0.60.91.5-0.6-0.11.11.1-1.2-1.20.2-1.1
Delay discounting water rate 12 sec0.30.51.3-0.6-1.20.80.7-0.7-0.3-0.80.2
Delay discounting water rate 18 sec0.40.51.1-0.7-0.71.10.9-0.9-0.5-0.1-0.4
Delay discounting water rate 24 sec2.43.36.0-1.1-1.62.32.2-2.4-1.8-0.5-1.6
Delay discounting water rate 6 sec0.00.10.30.50.40.00.10.1-0.10.2-0.2
Locomotor activity0.60.92.30.2-0.4-0.9-0.80.91.3-1.01.5
Locomotor testing distance0.91.53.80.2-0.3-1.4-1.11.31.5-1.12.0
Locomotor testing rearing0.10.10.3-0.4-0.50.1-0.00.00.5-0.50.4
Light reinforcement 10.20.31.71.30.10.20.5-0.4-0.20.2-0.4
Light reinforcement 21.41.83.71.41.4-1.9-1.31.71.00.61.0
Reaction time number correct1.11.52.30.90.21.31.3-1.5-1.41.1-1.5
Reaction time mean minus median0.60.81.21.01.0-1.1-1.11.00.60.50.5
Reaction time mean minus median AUC0.50.71.51.21.0-1.0-1.00.80.20.50.4
Reaction time num false alarms0.91.22.5-1.1-1.61.41.1-1.2-0.2-1.1-0.5
Reaction time num false alarms AUC0.81.13.3-1.2-1.81.00.7-0.80.3-1.50.0
Reaction time trials correct on left1.11.52.30.90.21.31.3-1.5-1.41.1-1.5
Reaction time trials on left1.01.52.20.90.11.31.3-1.5-1.41.0-1.5
Reaction time mean3.04.28.40.21.1-2.6-2.72.92.1-0.32.3
Reaction time mean AUC3.95.110.30.31.4-2.9-3.03.22.3-0.22.5
Median of all reaction times4.05.411.20.21.3-2.9-3.03.32.5-0.32.6
Reaction time omissions0.00.10.2-0.3-0.0-0.2-0.50.30.20.10.2
Reaction time false alarm rate0.71.02.7-1.4-1.60.40.2-0.20.7-1.70.5
Reaction time premature initiation rate0.60.81.6-0.5-1.21.11.3-1.1-0.5-0.4-0.4
Reaction time premature initiations1.62.34.50.1-1.22.02.1-2.1-1.40.1-1.4
Std. dev. reaction times0.81.22.30.60.7-1.5-1.51.40.9-0.01.1
Reaction time trials completed1.01.52.20.90.11.31.3-1.5-1.41.0-1.5
Reaction time trials AUC0.81.11.70.70.11.21.2-1.3-1.20.9-1.3
Social response proportion1.92.14.51.82.1-1.1-1.41.40.71.7-0.0
Social responses0.60.82.71.71.2-0.10.10.0-0.61.2-0.8
Social time0.20.30.7-0.5-0.4-0.5-0.50.50.1-0.80.8
Conditioned locomotion0.10.10.3-0.0-0.10.50.3-0.30.20.1-0.2
Cocaine response after cond. corrected0.80.92.60.5-0.30.81.2-1.1-1.60.2-0.9
Cocaine response after cond. not corrected2.02.24.3-0.3-1.21.61.9-1.9-2.1-0.4-1.2
Cocaine response before conditioning1.21.52.4-1.6-1.51.21.2-1.2-1.0-1.2-0.4
Saline control response2.12.86.4-0.7-0.21.72.1-1.9-2.50.6-2.0
Condit. Reinf. active minus inactive responses1.01.22.2-1.4-1.31.51.1-1.1-0.7-0.8-0.6
Condit. Reinf. active-inactive response ratio0.20.20.6-0.8-0.60.60.3-0.5-0.1-0.5-0.1
Condit. Reinf. active responses2.53.56.2-0.9-1.62.52.3-2.3-2.0-0.4-1.8
Condit. Reinf. inactive responses2.22.74.8-0.1-1.32.02.2-2.1-2.1-0.1-1.6
Condit. Reinf. lever presses0.30.40.70.1-0.60.70.8-0.9-0.6-0.2-0.5
Condit. Reinf. lever reinforcers received1.82.64.5-0.9-1.42.12.0-2.0-1.7-0.4-1.5
Pavlov. Cond. lever latency0.30.41.2-0.50.3-0.3-0.80.91.1-0.20.6
Pavlov. Cond. magazine entry latency0.50.61.5-0.9-0.8-0.3-0.20.30.6-1.20.9
Pavlov. Cond. change in total contacts0.71.01.7-0.8-0.91.11.3-1.3-1.2-0.5-0.8
Pavlov. Cond. index score0.60.81.4-0.6-1.20.81.0-1.1-0.8-0.7-0.3
Pavlov. Cond. latency score0.60.81.3-0.5-1.10.91.1-1.1-0.9-0.6-0.5
Pavlov. Cond. lever contacts0.30.41.00.1-0.50.50.8-0.8-1.0-0.0-0.5
Pavlov. Cond. magazine entry number0.81.02.51.41.10.30.3-0.3-0.71.6-1.2
Pavlov. Cond. intertrial magazine entries0.91.12.3-0.7-1.41.51.3-1.2-0.7-0.7-0.7
Pavlov. Cond. lever-magazine prob. diff.0.60.81.8-0.9-1.40.80.9-1.0-0.6-1.0-0.1
Pavlov. Cond. response bias0.30.51.3-0.7-1.10.30.6-0.6-0.4-1.00.2
Conditioned reinforcement - actives2.32.24.40.3-0.91.62.1-2.0-1.80.5-1.6
Conditioned reinforcement - inactives2.02.34.20.90.51.41.9-1.4-2.01.5-1.8
Conditioned locomotion0.80.91.81.21.00.20.7-0.5-1.01.4-1.1
Intermittent access intake day 1-15 change0.50.51.20.80.50.40.4-0.5-0.60.9-1.1
Intermittent access intake escalation0.20.20.50.60.30.20.2-0.3-0.40.6-0.7
Intermittent access intake escalation 20.40.40.70.50.8-0.5-0.70.90.60.5-0.0
Intermitt. access day 1 inactive lever presses1.01.12.51.11.10.30.4-0.6-1.21.6-1.2
Intermitt. access day 15 inactive lever presses3.43.87.22.31.01.11.8-1.6-2.72.2-2.3
Intermitt. access escalation Index0.30.30.7-0.80.10.50.5-0.3-0.70.1-0.8
Intermittent access day 1 total infusions1.11.22.0-0.2-0.51.41.3-1.4-1.30.4-1.3
Intermittent access day 15 total infusions1.92.13.7-0.1-0.61.71.8-1.9-1.70.6-1.9
Intermittent access terminal intake (last 3 days)0.91.02.60.10.21.01.1-1.0-1.20.9-1.6
Intermittent access total infusions0.60.71.6-0.20.01.00.9-0.9-0.80.6-1.3
Intermittent access day 1 locomotion0.80.81.8-0.7-0.71.20.9-1.3-0.70.1-0.9
Intermittent access day 15 total locomotion0.60.61.50.91.00.30.2-0.6-0.71.2-1.0
Intermittent access total locomotion0.10.10.3-0.10.30.30.2-0.4-0.10.5-0.6
Intermittent access standard deviation0.30.30.80.60.50.20.3-0.4-0.50.8-0.9
Cocaine induced anxiety0.10.10.2-0.1-0.20.40.2-0.5-0.3-0.0-0.4
Post-drug Anxiety0.80.91.61.20.80.10.3-0.8-1.21.1-1.2
Baseline Anxiety0.30.30.80.90.6-0.20.0-0.2-0.50.7-0.5
Lifetime Intake0.60.61.3-0.1-0.10.91.0-0.9-0.90.5-1.1
Incentive Sensitization - Responses0.60.61.50.2-0.11.00.7-1.2-0.50.5-1.1
Incentive Sensitization - Breakpoint0.80.81.70.40.01.10.8-1.3-0.70.7-1.3
Progressive ratio test 1 active lever presses2.02.13.90.60.31.41.4-1.6-2.01.4-2.0
Progressive ratio test 1 breakpoint1.71.73.30.50.31.21.2-1.4-1.81.4-1.8
Progressive ratio test 1 inactive lever presses2.72.96.00.3-0.11.82.1-2.1-2.41.1-2.0
Progressive ratio test 2 active lever presses1.31.32.90.50.21.31.1-1.4-1.21.1-1.7
Progressive ratio test 2 breakpoint1.71.94.60.70.31.51.1-1.6-1.41.5-2.1
Progressive ratio test 2 inactive lever presses1.72.03.81.61.20.80.9-0.7-1.61.9-1.9
Total sessions with >9 infusions0.30.30.8-0.6-0.50.50.3-0.9-0.6-0.1-0.4
Short access day 1 total inactive lever presses2.02.34.92.21.90.10.6-0.4-1.62.2-1.3
Short access day 10 total inactive lever presses0.91.03.70.30.50.51.3-0.7-1.90.6-0.9
Short access day 1 total infusions0.40.41.2-0.5-0.40.51.0-0.6-1.1-0.1-0.4
Short access day 10 total infusions0.10.10.3-0.5-0.2-0.10.1-0.1-0.3-0.2-0.1
Short access total infusions0.70.71.4-0.3-0.60.91.2-1.0-1.10.1-0.9
Short access day 1 locomotion0.30.31.9-1.4-0.30.20.1-0.1-0.3-0.30.1
Short access day 10 total locomotion0.20.20.4-0.40.4-0.4-0.70.40.60.10.2
Short access total locomotion0.10.10.5-0.7-0.2-0.2-0.20.00.2-0.30.3
Compulsive drug intake2.92.94.9-0.4-0.72.22.2-2.2-2.20.3-1.7
One hour access (0.3 mA shock)2.93.36.00.8-0.42.12.0-2.4-2.01.4-2.4
One hour access (shock baseline)0.10.10.30.5-0.0-0.1-0.3-0.10.40.5-0.2
Number of responses in last shaping day1.71.73.10.50.41.21.5-1.3-1.71.4-1.8
Context. condit. distance diff. score0.91.12.4-0.50.51.40.7-1.0-0.91.1-1.6
Locomotion velocity, session 12.62.85.31.00.9-2.3-2.12.01.7-0.21.9
Locomotion distance, session 10.30.40.70.20.4-0.8-0.80.80.80.00.7
Locomotion velocity, session 20.91.02.1-0.10.5-1.3-1.51.31.2-0.11.2
Locomotion distance, session 20.81.22.1-1.2-0.9-0.5-0.80.71.3-1.41.4
Locomotion velocity, session 30.10.10.4-0.6-0.50.50.3-0.20.0-0.4-0.0
Locomotion distance, session 30.50.52.2-1.5-0.80.90.4-0.30.0-0.6-0.1
Stereotopy head waving bouts, day 30.70.81.91.21.4-0.4-0.1-0.1-0.81.3-0.7
Stereotopy head waving duration, day 30.91.11.91.31.20.00.5-0.7-1.31.4-1.2
Locomotion velocity, session 71.01.12.2-1.0-0.51.51.2-1.1-0.90.1-1.1
Locomotion distance, session 70.81.12.2-0.8-0.51.51.4-1.2-0.90.1-1.2
Stereotopy head waving bouts, day 70.00.00.10.40.2-0.2-0.1-0.1-0.30.00.0
Stereotopy head waving duration, day 70.10.10.60.80.3-0.20.0-0.2-0.50.3-0.1
Locomotion velocity, session 80.00.10.20.10.40.0-0.20.00.20.4-0.2
Locomotion distance, session 80.20.31.2-1.10.40.5-0.30.20.40.4-0.3
Degree of sensitization distance0.30.30.60.0-0.10.50.7-0.8-0.60.2-0.7
Degree of sensitization stereotypy0.00.00.10.3-0.10.00.1-0.2-0.4-0.1-0.0
Condit. Reinf. active minus inactive responses0.60.71.8-1.4-1.0-0.1-0.30.20.4-1.30.9
Condit. Reinf. active-inactive response ratio1.11.11.9-0.20.5-1.4-1.41.41.2-0.31.3
Condit. Reinf. active responses1.21.42.4-1.5-1.31.41.2-1.3-1.0-0.9-0.6
Condit. Reinf. inactive responses3.13.66.1-0.9-1.52.42.4-2.5-2.2-0.3-1.9
Incentive salience index mean1.31.64.6-2.2-1.70.40.2-0.20.2-2.00.8
Condit. Reinf. lever presses0.91.14.3-2.1-1.30.40.3-0.2-0.1-1.70.5
Time in familiar zone, hab. session 10.10.10.50.70.3-0.00.3-0.1-0.40.3-0.3
Time in novel zone, hab. session 10.80.81.7-0.4-0.2-0.9-1.11.01.3-0.61.2
Total zone transitions, hab. session 10.00.00.10.3-0.10.10.20.00.10.0-0.0
Total locomotion distance, hab. session 10.60.92.2-0.4-0.0-0.8-0.91.11.5-0.61.3
Locomotion velocity, hab. session 10.71.02.3-0.80.0-0.8-1.01.21.5-0.61.3
Time in familiar zone, hab. session 20.20.20.40.50.5-0.6-0.40.40.20.20.3
Time in novel zone, hab. session 20.00.00.10.20.2-0.0-0.10.1-0.10.3-0.1
Total zone transitions, hab. session 20.30.41.1-0.2-0.7-0.5-0.30.30.6-1.01.0
Total locomotion distance, hab. session 21.21.63.3-0.4-0.3-1.2-1.41.41.8-1.11.8
Locomotion velocity, hab. session 21.31.83.5-0.7-0.5-1.1-1.31.41.9-1.31.8
Novel to familiar place preference ratio0.80.81.40.7-0.31.01.2-1.1-1.10.2-1.0
Novelty place preference0.70.71.11.0-0.10.81.0-0.9-0.90.4-1.0
Time in novel zone, NPP test0.20.20.80.9-0.10.40.6-0.4-0.30.1-0.5
Total zone transitions, NPP test0.71.02.0-1.1-1.1-0.5-0.60.51.1-1.41.4
Total locomotion distance, NPP test0.81.02.0-0.9-0.3-0.9-1.11.01.2-0.91.4
Locomotion velocity, NPP test0.40.51.3-1.1-0.6-0.3-0.50.40.5-1.00.9
Pavlov. Cond. lever latency0.60.83.81.90.8-0.6-0.20.2-0.01.1-0.1
Pavlov. Cond. magazine entry latency1.72.24.2-2.1-1.0-0.8-1.21.01.6-1.81.8
Pavlov. Cond. change in total contacts1.21.23.1-1.8-1.0-0.4-0.60.60.7-1.71.3
Pavlov. Cond. index score1.62.07.0-2.6-1.70.4-0.10.00.8-2.11.0
Pavlov. Cond. latency score1.72.17.9-2.8-1.90.80.3-0.40.4-2.10.6
Pavlov. Cond. lever contacts1.21.45.2-2.3-1.40.50.2-0.20.2-1.70.6
Pavlov. Cond. magazine entry number1.21.52.41.50.80.71.1-0.9-1.61.5-1.5
Pavlov. Cond. intertrial magazine entries1.72.03.5-0.3-1.01.71.8-1.9-1.7-0.2-1.4
Pavlov. Cond. lever-magazine prob. diff.1.82.37.0-2.6-1.70.1-0.50.41.1-2.21.4
Pavlov. Cond. response bias1.92.33.7-1.7-0.9-1.0-1.31.31.9-1.81.9
Bone: apparent density4.88.012.42.6-0.22.93.3-3.3-3.31.9-3.5
Bone surface3.25.69.41.9-0.32.32.8-2.8-3.11.4-2.9
Bone volume3.86.410.21.5-0.82.93.2-3.2-3.01.1-3.1
Bone: connectivity density3.04.77.72.80.71.62.1-2.0-2.62.0-2.7
Bone: cortical apparent density0.40.51.20.31.1-1.0-0.70.7-0.20.60.2
Bone: cortical area3.35.08.9-0.9-2.22.92.8-3.0-2.2-0.7-2.0
Bone: cortical porosity0.30.30.7-0.30.4-0.6-0.70.80.8-0.20.6
Bone: cortical porosity0.10.10.2-0.20.1-0.2-0.20.30.5-0.20.2
Bone: cortical thickness2.13.57.3-1.5-2.72.02.0-2.2-1.4-1.8-0.6
Bone: cortical thickness0.50.61.5-1.0-1.20.50.4-0.4-0.1-1.10.4
Bone: cortical tissue density0.50.61.40.41.2-1.1-0.80.9-0.00.60.3
Bone: elastic displacement5.25.910.11.42.7-3.0-3.23.12.21.31.8
Bone: elastic work3.64.79.11.73.0-2.5-2.62.41.61.90.9
Bone: endosteal estimation2.45.210.21.50.22.52.6-2.4-2.51.9-3.2
Bone: endosteal perimeter1.42.85.61.70.51.71.5-1.6-1.42.0-2.4
Bone: final force0.91.52.6-0.4-1.41.51.6-1.6-1.0-0.7-0.9
Bone: final moment0.71.12.10.0-1.11.31.4-1.4-0.9-0.4-0.9
Bone: marrow area2.65.611.01.60.32.52.6-2.5-2.62.0-3.3
Bone: maximum diameter3.87.013.61.4-0.13.23.0-3.1-2.82.1-3.7
Bone: maximum force1.52.74.90.4-1.02.02.1-2.2-1.80.2-1.9
Bone: maximum moment1.32.24.00.8-0.71.71.9-2.0-1.70.4-1.7
Bone: minimum diameter2.75.19.30.1-1.03.12.8-2.9-2.30.7-2.8
Bone: periosteal estimation3.26.510.70.8-0.83.23.2-3.1-2.81.2-3.3
Bone: periosteal perimeter2.23.77.00.3-0.82.62.4-2.4-2.00.7-2.4
Bone: post-yield work4.15.69.6-0.6-2.62.83.1-3.1-2.4-1.2-1.7
Bone: stiffness2.43.87.0-1.0-1.92.62.5-2.5-1.6-0.8-1.7
Bone: tissue strength0.40.40.90.90.6-0.9-0.50.50.30.20.4
Bone: trabecular number3.65.68.12.6-0.22.22.7-2.7-2.81.5-2.8
Bone: trabecular spacing1.01.34.5-2.1-1.0-0.3-0.40.40.6-1.51.2
Bone: trabecular thickness1.72.03.31.4-0.51.61.8-1.7-1.40.7-1.7
Bone: trabecular tissue density1.72.35.50.40.61.61.5-1.6-1.71.6-2.3
Breakpoint value in progressive ratio session2.12.44.1-0.8-1.71.92.0-1.9-1.5-0.7-1.2
Distance traveled before self-admin0.10.10.8-0.90.10.30.1-0.2-0.2-0.1-0.2
Distance traveled after self-admin2.12.35.02.21.70.30.8-0.7-1.42.1-1.7
Delta time in closed arm before/after self-admin4.34.17.7-1.7-1.5-1.2-1.81.42.7-2.52.8
Delta time in open arm before/after self-admin2.52.44.71.01.21.01.4-1.0-2.11.9-2.2
Diff in mean of infusions in LGA sessions0.30.41.0-1.0-0.40.1-0.70.50.9-0.40.3
Extinction: sum of active levers before priming0.40.40.9-0.9-0.90.80.6-0.6-0.3-0.3-0.2
Active lever presses in extinction session 61.71.63.60.1-0.61.71.9-1.4-1.40.2-1.5
Delta distance traveled before/after self-admin1.92.03.91.91.10.60.9-1.0-1.42.0-1.7
Delta ambulatory time before/after self-admin3.74.06.91.91.01.41.9-1.9-2.42.3-2.6
Time in closed arm before self-admin0.30.30.60.70.70.00.40.1-0.70.8-0.5
Time in closed arm after self-admin1.01.02.6-1.4-1.3-0.1-0.20.10.7-1.61.1
Time in open arm before self-admin0.70.71.7-0.3-0.3-0.7-0.90.81.3-0.91.1
Time in open arm after self-admin0.70.81.91.40.50.60.8-0.5-0.81.0-1.0
Sum of active levers in priming session hrs 5-60.40.41.71.30.7-0.50.1-0.1-0.60.7-0.4
Time to tail flick, vehicle, before self-admin0.60.61.20.71.1-1.0-1.00.70.40.50.1
Time to tail flick, vehicle, after self-admin1.61.73.6-1.5-1.91.51.3-1.5-0.4-1.1-0.3
Time to tail flick, test, before self-admin1.61.63.8-0.20.11.61.3-1.5-1.21.1-2.0
Time to tail flick, test, after self-admin0.60.61.6-0.3-0.10.70.8-1.2-1.30.2-0.8
Delta time to tail flick, vehicle, before/after SA3.63.56.6-1.7-2.52.62.3-2.1-1.0-1.1-0.9
Delta time to tail flick, test, before/after SA0.20.20.4-0.5-0.60.20.3-0.5-0.4-0.70.4
Ambulatory time before self-admin0.40.40.9-1.00.3-0.5-0.90.70.6-0.30.6
Ambulatory time after self-admin2.02.24.91.71.90.40.6-0.6-1.32.2-1.8
Total heroin consumption1.82.14.5-0.3-1.01.72.1-2.0-1.6-0.2-1.5
Area under the delay curve2.62.84.7-0.7-2.01.62.0-2.1-2.2-1.0-1.0
Delay disc. indifference point, 0s delay2.52.74.4-1.1-1.72.02.1-2.1-1.6-0.9-1.2
Delay disc. indifference point, 16s delay3.13.16.60.2-1.31.82.1-2.6-2.6-0.0-1.7
Delay disc. indifference point, 2s delay0.91.02.70.5-0.30.81.1-1.2-1.70.3-1.1
Delay disc. indifference point, 24s delay2.42.43.8-1.4-1.81.41.8-1.7-1.9-1.2-0.5
Delay disc. indifference point, 4s delay2.93.14.7-1.1-2.11.92.2-2.1-1.9-1.1-1.0
Delay disc. indifference point, 8s delay1.11.12.4-0.5-1.60.51.1-1.2-1.4-1.1-0.2
Delay discount exponential model param2.62.74.40.72.1-1.6-1.92.12.11.10.8
Delay discount hyperbolic model param2.22.34.40.61.8-1.4-1.82.02.10.90.9
Fecal boli incidents, locomotor time 10.20.20.7-0.30.80.30.2-0.2-0.40.6-0.7
Change in fecal boli incidents, locomotor task0.10.10.3-0.2-0.50.00.1-0.1-0.1-0.50.3
Time >=10cm from walls, locomotor time 13.13.16.7-0.9-1.42.41.9-2.6-1.50.1-1.8
Bouts of movement, locomotor time 10.50.61.6-0.3-1.20.20.1-0.20.7-1.30.8
Total resting periods, locomotor time 10.60.72.0-0.4-1.40.70.9-0.70.0-1.20.3
Rest time, locomotor task time 10.10.20.70.80.5-0.3-0.20.1-0.10.3-0.1
Distance moved, locomotor task time 11.01.12.4-1.5-1.41.01.1-1.0-0.6-1.0-0.4
Vertical activity count, locomotor time 10.10.10.3-0.4-0.5-0.0-0.1-0.00.4-0.40.4
Time >=10cm from walls, locomotor time 22.72.96.0-1.1-1.62.02.0-2.4-1.8-0.6-1.3
Bouts of movement, locomotor time 20.70.81.6-1.0-0.6-0.6-0.80.50.7-1.31.2
Total resting periods, locomotor time 21.11.22.5-1.2-0.9-0.7-0.90.61.0-1.61.5
Rest time, locomotor task time 21.21.43.1-0.8-1.4-0.4-0.40.41.7-1.81.6
Distance moved, locomotor task time 21.01.12.2-0.8-0.11.21.1-1.1-1.50.5-1.4
Vertical activity count, locomotor time 20.20.30.80.10.6-0.00.1-0.3-0.90.7-0.6
Weight adjusted by age0.40.51.51.20.30.00.3-0.7-0.60.8-0.7
Seeking ratio, delayed vs. immediate footshock0.30.40.8-0.40.3-0.3-0.70.90.9-0.40.7
Locomotion in novel chamber1.31.63.71.31.9-0.5-1.11.31.11.7-0.3
Locomotion in novel chamber post-restriction1.11.33.5-0.5-0.91.91.3-1.3-0.80.2-1.4
Progressive ratio0.50.51.6-1.3-0.80.4-0.10.30.7-1.00.5
Food seeking constrained by brief footshock0.40.41.2-0.7-1.10.5-0.00.20.8-0.70.6
Seeking ratio, punishment vs. effort0.10.10.30.3-0.60.10.2-0.4-0.2-0.20.1
Run reversals in cocaine runway, females0.70.71.21.11.0-0.9-0.81.00.60.70.1
Run reversals in cocaine runway, males0.80.81.6-0.8-1.2-0.3-0.40.21.0-1.31.2
Latency to leave start box in cocaine runway0.80.92.00.10.90.90.1-0.6-0.91.4-1.4
Latency to leave start box in cocaine runway, F0.40.51.1-0.31.00.4-0.4-0.3-0.51.1-0.9
Latency to leave start box in cocaine runway, M0.40.40.80.2-0.40.90.7-0.6-0.50.4-0.7
Cd content in liver0.10.10.3-0.1-0.5-0.10.2-0.2-0.4-0.50.1
Co content in liver1.31.53.61.71.9-1.2-0.70.8-0.41.5-0.2
Cu content in liver0.70.92.41.40.2-1.5-0.80.90.3-0.31.1
Fe content in liver4.35.29.4-0.9-0.0-2.4-2.72.62.8-1.73.1
K content in liver0.20.20.6-0.30.3-0.4-0.60.50.8-0.10.4
Mg content in liver0.30.30.6-0.4-0.0-0.7-0.60.60.6-0.60.7
Mn content in liver0.80.92.0-0.6-0.5-1.0-0.90.81.0-1.21.4
Na content in liver0.91.02.0-1.4-0.4-0.6-1.00.71.0-1.11.3
Rb content in liver0.20.20.7-0.4-0.80.50.2-0.20.2-0.60.1
Se content in liver11.413.828.2-1.0-0.1-4.7-4.34.13.9-3.05.3
Sr content in liver1.41.33.61.91.7-0.5-0.20.3-0.51.7-0.7
Zn content in liver6.77.412.0-1.50.7-3.1-3.53.33.1-1.53.4