Hub : Genes

Ankrd1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression ENSRNOG00000018598 0.06 0.05 1.1e-03 0.02 0.04 0.02 0.03 5.5e-03 9.1e-05 9.0e-03 1.7e-03
2 NAcc alternative TSS ENSRNOT00000108356 0.08 0.05 2.1e-03 0.04 0.03 0.04 0.03 8.5e-04 1.8e-03 1.2e-03 2.1e-03
3 NAcc alternative TSS ENSRNOT00000117221 0.05 0.03 6.8e-03 0.03 0.03 0.03 0.03 4.6e-03 1.4e-03 3.4e-03 1.9e-03
4 NAcc alternative TSS ENSRNOT00000108356 0.08 0.05 1.4e-03 0.03 0.04 0.04 0.03 4.0e-03 7.1e-04 7.0e-04 1.6e-03
5 NAcc alternative TSS ENSRNOT00000117221 0.06 0.04 3.3e-03 0.03 0.04 0.03 0.04 2.8e-03 7.4e-04 1.8e-03 1.2e-03
6 PL alternative TSS ENSRNOT00000108356 0.04 0.03 6.1e-03 0.02 0.01 0.02 0 8.9e-03 2.6e-02 2.0e-02 2.6e-01
7 PL alternative TSS ENSRNOT00000117221 0.03 0.02 6.2e-03 0.01 0.01 0 -0 2.4e-02 6.6e-02 1.8e-01 3.9e-01
8 PL alternative TSS ENSRNOT00000117221 0.03 0.02 5.4e-03 0.02 0.01 0 0 2.1e-02 5.4e-02 1.8e-01 3.3e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.10.20.5-0.7-0.3-0.5-0.1-0.50.1-0.3-0.3
BMI without tail0.30.62.0-1.4-1.10.3-0.90.30.0-0.4-0.4
Body weight1.66.612.2-2.5-3.23.0-3.53.01.4-1.4-1.4
Epididymis fat weight1.02.46.2-0.6-2.51.8-2.51.90.1-0.2-0.2
Glucose0.10.10.50.5-0.70.3-0.40.30.0-0.0-0.0
Heart weight0.40.51.31.0-1.10.1-1.00.1-0.50.70.7
Left kidney weight1.64.69.4-0.6-2.93.0-3.13.0-0.20.30.3
Right kidney weight2.57.314.00.3-3.73.6-3.73.6-1.21.31.3
Tail length2.16.310.7-3.0-2.83.2-3.13.30.8-1.0-1.0
Length with tail3.011.022.5-2.9-3.54.7-4.24.71.4-1.3-1.3
Length without tail1.94.29.9-1.3-1.63.1-2.33.21.4-1.0-1.0
Liver weight, left1.93.15.4-1.2-1.62.3-2.02.31.6-1.4-1.4
Liver weight, right2.13.67.6-1.3-2.32.7-2.52.80.10.00.0
Parametrial fat weight1.12.13.8-1.4-1.81.9-1.91.90.2-0.1-0.1
Retroperitoneal fat weight0.31.02.6-0.6-1.61.0-1.51.00.5-0.6-0.6
Intraocular pressure0.40.51.00.1-0.80.3-0.80.30.8-1.0-1.0
Extensor digitorum longus weight0.62.54.5-2.1-2.01.7-2.11.71.0-0.7-0.7
Soleus weight0.82.32.7-1.21.6-1.51.5-1.51.6-1.6-1.6
Tibialis anterior weight0.82.78.6-2.9-1.51.4-1.71.41.3-1.2-1.2
Tibia length0.20.61.4-0.3-0.61.2-0.81.20.4-0.4-0.4
Number of licking bursts2.32.76.42.5-1.21.6-1.31.6-1.61.51.5
Food consumed during 24 hour testing period0.91.11.71.0-1.31.1-1.31.1-0.60.80.8
Times rat made contact with spout0.50.61.3-1.2-0.60.9-0.80.90.5-0.5-0.5
Mean time between licks in bursts1.01.43.61.90.4-0.70.7-0.8-1.51.31.3
Mean num. licks in bursts2.22.69.2-3.00.8-1.10.8-1.11.8-1.6-1.6
Std. dev. time between licks in bursts1.92.35.82.4-0.3-0.40.2-0.4-1.92.02.0
Water consumed over 24 hours0.60.72.0-0.2-0.71.4-1.01.4-0.00.30.3
Indifference point 0 sec1.11.83.90.3-2.01.6-1.91.6-0.70.70.7
Indifference point AUC1.61.83.5-0.8-1.91.2-1.61.2-1.51.21.2
Indifference point function ln k0.91.23.50.01.1-0.30.7-0.31.9-1.5-1.5
Indifference point function log k0.91.23.50.01.1-0.30.7-0.31.9-1.5-1.5
Delay discounting total patch changes 0 sec1.01.63.50.3-1.91.5-1.91.6-0.70.60.6
Delay discounting total patch changes 12 sec1.21.53.00.4-1.50.6-1.10.6-1.71.61.6
Delay discounting total patch changes 18 sec0.81.12.5-0.4-1.61.1-1.51.2-0.70.40.4
Delay discounting total patch changes 24 sec2.63.37.7-0.2-2.82.2-2.82.2-0.80.60.6
Delay discounting total patch changes 6 sec1.72.65.10.2-2.31.4-1.91.5-1.81.61.6
Delay discounting time to switch 0 sec0.81.26.12.50.8-0.60.9-0.6-0.70.80.8
Delay discounting water rate 0 sec0.30.52.2-1.5-0.80.3-0.80.30.4-0.5-0.5
Delay discounting water rate 12 sec0.30.41.2-0.3-0.21.1-0.51.10.5-0.1-0.1
Delay discounting water rate 18 sec0.40.50.8-0.8-0.40.8-0.70.80.9-0.4-0.4
Delay discounting water rate 24 sec1.42.04.0-2.0-1.21.6-1.51.61.1-0.9-0.9
Delay discounting water rate 6 sec0.10.10.3-0.2-0.1-0.3-0.0-0.30.6-0.5-0.5
Locomotor activity0.20.42.01.4-0.30.2-0.20.2-0.50.50.5
Locomotor testing distance0.50.93.61.9-0.10.1-0.10.1-1.11.01.0
Locomotor testing rearing0.10.20.30.2-0.50.5-0.50.50.2-0.3-0.3
Light reinforcement 10.30.51.2-0.10.3-0.50.2-0.51.1-1.0-1.0
Light reinforcement 21.52.02.71.61.3-1.61.5-1.6-1.11.11.1
Reaction time number correct1.31.84.5-1.50.9-0.30.6-0.32.1-1.8-1.8
Reaction time mean minus median0.40.51.20.90.6-1.10.8-1.1-0.30.20.2
Reaction time mean minus median AUC0.40.51.40.80.4-1.20.6-1.2-0.50.30.3
Reaction time num false alarms1.21.63.1-0.8-1.61.5-1.81.50.8-0.9-0.9
Reaction time num false alarms AUC1.11.63.5-0.2-1.71.7-1.91.70.3-0.4-0.4
Reaction time trials correct on left1.31.84.5-1.50.9-0.30.6-0.32.1-1.8-1.8
Reaction time trials on left1.31.84.4-1.50.9-0.20.5-0.22.1-1.8-1.8
Reaction time mean1.72.35.92.40.3-0.90.8-0.9-2.01.81.8
Reaction time mean AUC2.33.17.02.60.4-1.10.9-1.1-2.22.12.1
Median of all reaction times2.12.97.22.70.4-1.01.0-1.1-2.12.02.0
Reaction time omissions0.00.00.10.2-0.10.00.00.0-0.4-0.2-0.2
Reaction time false alarm rate1.01.53.40.3-1.81.6-1.81.6-0.40.10.1
Reaction time premature initiation rate0.40.51.1-0.6-0.11.0-0.41.00.8-0.7-0.7
Reaction time premature initiations1.31.94.5-1.50.20.9-0.20.92.1-1.8-1.8
Std. dev. reaction times0.60.82.01.40.2-0.80.5-0.8-1.20.90.9
Reaction time trials completed1.31.84.4-1.50.9-0.20.5-0.22.1-1.8-1.8
Reaction time trials AUC1.01.43.5-1.40.8-0.20.5-0.21.9-1.5-1.5
Social response proportion2.22.44.50.42.1-2.12.1-2.10.9-0.6-0.6
Social responses0.71.01.9-0.30.9-1.41.0-1.40.9-0.7-0.7
Social time0.70.91.90.8-0.70.4-0.40.4-1.31.41.4
Conditioned locomotion0.50.61.6-0.40.40.20.10.21.1-1.3-1.3
Cocaine response after cond. corrected0.20.20.7-0.80.5-0.10.3-0.00.3-0.5-0.5
Cocaine response after cond. not corrected0.50.61.9-1.4-0.40.9-0.60.90.3-0.5-0.5
Cocaine response before conditioning1.41.72.7-0.8-1.61.6-1.61.6-0.70.90.9
Saline control response0.50.74.7-2.20.00.4-0.10.40.1-0.5-0.5
Condit. Reinf. active minus inactive responses1.21.52.7-1.2-1.51.4-1.71.40.5-0.7-0.7
Condit. Reinf. active-inactive response ratio0.40.41.0-0.5-1.00.7-1.00.70.1-0.4-0.4
Condit. Reinf. active responses1.72.44.9-2.2-1.11.4-1.41.41.4-1.6-1.6
Condit. Reinf. inactive responses0.91.22.9-1.7-0.30.9-0.60.91.1-1.2-1.2
Condit. Reinf. lever presses0.20.20.6-0.4-0.20.4-0.30.40.5-0.8-0.8
Condit. Reinf. lever reinforcers received1.21.83.4-1.9-1.01.2-1.31.31.1-1.3-1.3
Pavlov. Cond. lever latency0.00.00.10.3-0.30.2-0.30.10.20.10.1
Pavlov. Cond. magazine entry latency0.50.60.90.7-0.90.9-0.80.9-1.00.60.6
Pavlov. Cond. change in total contacts0.30.50.9-1.0-0.70.9-0.80.9-0.20.10.1
Pavlov. Cond. index score0.30.40.9-0.5-0.70.9-0.71.0-0.2-0.2-0.2
Pavlov. Cond. latency score0.30.40.8-0.6-0.60.9-0.70.9-0.0-0.4-0.4
Pavlov. Cond. lever contacts0.00.00.1-0.40.10.20.10.2-0.1-0.2-0.2
Pavlov. Cond. magazine entry number1.11.31.9-0.81.2-1.21.1-1.21.4-1.0-1.0
Pavlov. Cond. intertrial magazine entries0.91.21.7-1.0-0.91.3-1.21.31.0-1.0-1.0
Pavlov. Cond. lever-magazine prob. diff.0.50.61.4-0.3-0.91.2-1.01.2-0.3-0.0-0.0
Pavlov. Cond. response bias0.40.50.80.2-0.70.9-0.70.9-0.90.50.5
Conditioned reinforcement - actives0.70.71.9-1.40.40.60.10.61.0-1.0-1.0
Conditioned reinforcement - inactives1.31.53.2-1.81.3-0.61.0-0.51.3-1.3-1.3
Conditioned locomotion0.80.91.6-0.71.2-1.11.3-1.10.6-0.6-0.6
Intermittent access intake day 1-15 change0.40.40.6-0.60.5-0.70.5-0.70.7-0.8-0.8
Intermittent access intake escalation0.10.10.2-0.30.2-0.40.3-0.40.4-0.4-0.4
Intermittent access intake escalation 20.20.20.50.20.2-0.70.3-0.70.3-0.3-0.3
Intermitt. access day 1 inactive lever presses1.11.11.6-0.91.3-1.21.1-1.20.9-0.9-0.9
Intermitt. access day 15 inactive lever presses2.83.15.8-1.72.4-1.62.0-1.61.6-1.6-1.6
Intermitt. access escalation Index0.30.20.7-0.8-0.40.2-0.20.2-0.60.50.5
Intermittent access day 1 total infusions0.50.62.0-1.40.20.5-0.20.50.8-0.8-0.8
Intermittent access day 15 total infusions0.60.73.0-1.7-0.00.5-0.30.50.9-0.8-0.8
Intermittent access terminal intake (last 3 days)0.30.31.7-1.30.2-0.10.2-0.10.6-0.5-0.5
Intermittent access total infusions0.40.41.6-1.30.00.2-0.20.20.7-0.7-0.7
Intermittent access day 1 locomotion0.50.51.3-1.1-0.40.8-0.60.80.5-0.5-0.5
Intermittent access day 15 total locomotion0.60.60.9-0.80.7-0.90.7-0.90.8-0.7-0.7
Intermittent access total locomotion0.10.10.4-0.6-0.0-0.1-0.0-0.10.3-0.3-0.3
Intermittent access standard deviation0.30.30.5-0.40.7-0.60.6-0.50.4-0.4-0.4
Cocaine induced anxiety0.00.00.1-0.3-0.10.1-0.10.10.0-0.0-0.0
Post-drug Anxiety0.60.61.2-0.61.0-1.11.0-1.10.3-0.3-0.3
Baseline Anxiety0.30.30.7-0.10.7-0.80.7-0.80.3-0.3-0.3
Lifetime Intake0.20.31.1-1.10.10.3-0.10.20.5-0.5-0.5
Incentive Sensitization - Responses0.80.81.9-1.10.1-0.0-0.1-0.01.4-1.3-1.3
Incentive Sensitization - Breakpoint0.90.92.0-1.20.2-0.1-0.0-0.11.4-1.4-1.4
Progressive ratio test 1 active lever presses1.11.13.2-1.81.0-0.30.8-0.31.1-1.1-1.1
Progressive ratio test 1 breakpoint0.91.02.7-1.61.0-0.40.9-0.41.0-1.0-1.0
Progressive ratio test 1 inactive lever presses1.21.34.2-2.00.9-0.10.6-0.01.2-1.3-1.3
Progressive ratio test 2 active lever presses1.21.32.6-1.60.6-0.10.2-0.11.6-1.6-1.6
Progressive ratio test 2 breakpoint1.82.03.8-1.80.8-0.40.4-0.41.9-1.9-1.9
Progressive ratio test 2 inactive lever presses1.72.02.8-1.41.7-1.31.4-1.31.5-1.4-1.4
Total sessions with >9 infusions0.10.10.2-0.4-0.30.5-0.40.5-0.30.30.3
Short access day 1 total inactive lever presses2.83.14.9-1.02.2-2.12.1-2.11.4-1.4-1.4
Short access day 10 total inactive lever presses0.30.40.8-0.90.8-0.60.8-0.6-0.30.30.3
Short access day 1 total infusions0.20.20.3-0.50.00.5-0.10.5-0.50.50.5
Short access day 10 total infusions0.30.40.90.0-0.10.3-0.10.3-0.90.90.9
Short access total infusions0.20.20.7-0.90.10.5-0.10.60.2-0.2-0.2
Short access day 1 locomotion0.60.60.9-0.4-0.90.7-0.90.7-0.80.90.9
Short access day 10 total locomotion0.00.00.10.2-0.1-0.10.0-0.2-0.30.20.2
Short access total locomotion0.20.20.50.2-0.30.3-0.30.3-0.70.70.7
Compulsive drug intake1.91.95.5-2.3-0.90.8-1.00.81.4-1.5-1.5
One hour access (0.3 mA shock)2.22.55.1-2.20.50.10.00.12.2-2.2-2.2
One hour access (shock baseline)0.10.20.60.30.7-0.20.5-0.20.4-0.3-0.3
Number of responses in last shaping day0.80.82.6-1.60.7-0.40.5-0.40.9-1.0-1.0
Context. condit. distance diff. score1.51.84.6-2.2-0.40.0-0.50.01.7-1.8-1.8
Locomotion velocity, session 12.12.35.42.30.6-1.10.9-1.1-1.71.71.7
Locomotion distance, session 10.20.20.60.80.2-0.40.3-0.4-0.40.50.5
Locomotion velocity, session 20.50.61.41.1-0.1-0.40.1-0.4-1.20.90.9
Locomotion distance, session 20.81.11.51.0-1.21.0-1.21.0-0.90.90.9
Locomotion velocity, session 30.20.30.4-0.3-0.60.6-0.60.60.3-0.5-0.5
Locomotion distance, session 30.80.81.5-0.8-1.21.1-1.21.10.4-0.5-0.5
Stereotopy head waving bouts, day 30.80.92.1-0.31.1-1.51.3-1.5-0.1-0.2-0.2
Stereotopy head waving duration, day 30.81.01.8-0.71.2-1.31.3-1.30.2-0.5-0.5
Locomotion velocity, session 70.80.92.4-1.5-0.40.9-0.60.90.9-1.0-1.0
Locomotion distance, session 70.70.92.2-1.5-0.20.7-0.40.81.1-1.0-1.0
Stereotopy head waving bouts, day 70.10.10.20.10.0-0.30.1-0.3-0.40.20.2
Stereotopy head waving duration, day 70.10.10.30.10.3-0.60.5-0.6-0.40.10.1
Locomotion velocity, session 80.10.10.2-0.20.1-0.20.1-0.20.3-0.4-0.4
Locomotion distance, session 80.30.51.0-1.0-0.90.3-0.80.20.7-0.6-0.6
Degree of sensitization distance0.10.10.3-0.50.20.10.10.10.2-0.0-0.0
Degree of sensitization stereotypy0.00.00.00.00.0-0.10.1-0.1-0.20.00.0
Condit. Reinf. active minus inactive responses0.70.81.10.5-1.01.0-1.01.0-1.00.60.6
Condit. Reinf. active-inactive response ratio0.70.81.91.40.2-0.30.4-0.4-1.21.11.1
Condit. Reinf. active responses0.91.12.0-1.1-1.21.4-1.31.4-0.0-0.5-0.5
Condit. Reinf. inactive responses1.82.15.1-2.2-0.91.3-1.21.31.1-1.6-1.6
Incentive salience index mean1.82.23.70.2-1.91.8-1.91.9-1.21.01.0
Condit. Reinf. lever presses1.62.23.8-0.1-1.91.6-1.81.6-1.31.41.4
Time in familiar zone, hab. session 10.20.20.7-0.00.8-0.40.8-0.40.2-0.2-0.2
Time in novel zone, hab. session 10.40.41.11.1-0.60.3-0.50.3-0.70.60.6
Total zone transitions, hab. session 10.10.20.40.10.6-0.20.5-0.10.4-0.6-0.6
Total locomotion distance, hab. session 10.20.21.31.10.30.20.30.2-0.50.10.1
Locomotion velocity, hab. session 10.20.21.01.0-0.00.3-0.00.2-0.60.40.4
Time in familiar zone, hab. session 20.30.30.40.50.4-0.50.5-0.5-0.60.60.6
Time in novel zone, hab. session 20.10.10.2-0.10.2-0.30.3-0.30.2-0.4-0.4
Total zone transitions, hab. session 20.40.51.01.0-0.40.4-0.30.4-0.90.80.8
Total locomotion distance, hab. session 20.50.72.61.6-0.40.3-0.30.3-1.10.90.9
Locomotion velocity, hab. session 20.60.82.51.6-0.60.5-0.50.5-1.00.90.9
Novel to familiar place preference ratio0.40.51.4-0.80.2-0.00.0-0.01.2-0.9-0.9
Novelty place preference0.60.61.7-0.80.4-0.20.2-0.21.3-1.0-1.0
Time in novel zone, NPP test0.30.31.2-0.20.3-0.10.2-0.11.1-0.8-0.8
Total zone transitions, NPP test0.81.21.31.0-1.11.1-1.01.1-1.11.11.1
Total locomotion distance, NPP test0.60.81.41.1-0.90.5-0.70.5-1.21.11.1
Locomotion velocity, NPP test0.60.91.30.5-1.10.8-1.00.8-1.11.11.1
Pavlov. Cond. lever latency1.11.43.20.51.8-1.31.7-1.30.6-0.8-0.8
Pavlov. Cond. magazine entry latency1.92.53.21.2-1.71.3-1.51.3-1.71.81.8
Pavlov. Cond. change in total contacts1.92.03.30.8-1.51.2-1.31.2-1.81.71.7
Pavlov. Cond. index score2.43.15.90.2-2.42.1-2.42.1-1.11.31.3
Pavlov. Cond. latency score2.73.46.8-0.3-2.62.3-2.62.3-0.91.11.1
Pavlov. Cond. lever contacts1.92.34.3-0.1-2.11.8-2.01.8-1.01.11.1
Pavlov. Cond. magazine entry number1.21.51.9-1.11.4-1.11.2-1.01.1-1.4-1.4
Pavlov. Cond. intertrial magazine entries0.81.02.3-1.5-0.40.8-0.70.90.9-1.2-1.2
Pavlov. Cond. lever-magazine prob. diff.2.73.35.80.6-2.42.1-2.32.1-1.41.61.6
Pavlov. Cond. response bias1.92.33.41.5-1.51.2-1.31.1-1.61.81.8
Bone: apparent density4.47.316.3-2.91.8-0.71.2-0.74.0-3.8-3.8
Bone surface2.13.77.3-2.41.2-0.60.7-0.52.7-2.6-2.6
Bone volume3.05.011.1-2.70.80.10.20.13.3-3.2-3.2
Bone: connectivity density2.94.57.6-1.92.1-1.51.8-1.52.8-2.5-2.5
Bone: cortical apparent density0.60.81.80.50.7-1.00.9-1.0-1.40.80.8
Bone: cortical area2.43.65.7-2.4-1.51.9-1.81.91.8-1.9-1.9
Bone: cortical porosity0.10.10.30.5-0.0-0.10.1-0.1-0.40.40.4
Bone: cortical porosity0.00.00.00.2-0.20.1-0.10.10.00.10.1
Bone: cortical thickness1.72.75.6-1.1-2.02.3-2.32.40.1-0.5-0.5
Bone: cortical thickness0.60.71.4-0.0-1.01.2-1.11.2-0.5-0.2-0.2
Bone: cortical tissue density0.70.91.80.60.8-1.11.0-1.1-1.30.80.8
Bone: elastic displacement3.13.55.92.21.7-2.42.1-2.4-1.11.21.2
Bone: elastic work2.63.47.61.41.8-2.72.2-2.8-0.60.80.8
Bone: endosteal estimation2.35.011.7-2.91.1-0.60.6-0.53.4-3.0-3.0
Bone: endosteal perimeter2.14.311.9-2.01.3-0.90.9-0.83.4-2.7-2.7
Bone: final force0.71.11.6-1.1-1.11.2-1.31.20.9-0.8-0.8
Bone: final moment0.40.60.9-0.8-0.70.8-0.80.80.9-0.7-0.7
Bone: marrow area2.55.312.5-2.91.2-0.70.7-0.63.5-3.1-3.1
Bone: maximum diameter4.58.318.2-3.51.0-0.30.4-0.24.3-4.1-4.1
Bone: maximum force1.01.73.4-1.8-0.40.6-0.70.61.8-1.6-1.6
Bone: maximum moment0.71.23.1-1.5-0.00.2-0.30.31.8-1.5-1.5
Bone: minimum diameter2.44.49.8-3.0-0.50.8-0.90.93.1-2.6-2.6
Bone: periosteal estimation2.65.311.9-3.20.30.4-0.30.43.5-3.2-3.2
Bone: periosteal perimeter2.23.68.7-2.6-0.10.6-0.50.62.9-2.5-2.5
Bone: post-yield work2.12.84.1-2.0-1.62.0-2.02.01.4-1.1-1.1
Bone: stiffness2.03.14.7-2.2-1.81.9-2.11.91.7-1.3-1.3
Bone: tissue strength0.70.60.90.90.6-0.80.7-0.8-0.50.90.9
Bone: trabecular number2.74.39.2-2.11.7-0.81.2-0.73.0-2.7-2.7
Bone: trabecular spacing1.72.23.60.7-1.41.4-1.21.4-1.91.71.7
Bone: trabecular thickness2.02.56.5-1.31.0-0.10.5-0.12.6-2.3-2.3
Bone: trabecular tissue density1.72.35.0-2.20.6-0.60.5-0.51.9-2.1-2.1
Breakpoint value in progressive ratio session1.11.21.9-1.3-0.81.4-1.01.40.8-0.9-0.9
Distance traveled before self-admin0.20.20.7-0.6-0.90.3-0.60.3-0.40.20.2
Distance traveled after self-admin2.52.84.1-1.11.9-2.01.9-2.01.4-1.4-1.4
Delta time in closed arm before/after self-admin3.02.94.72.2-1.81.6-1.71.6-1.61.51.5
Delta time in open arm before/after self-admin1.71.63.5-1.91.2-1.21.1-1.21.2-1.0-1.0
Diff in mean of infusions in LGA sessions0.30.30.70.1-0.80.7-0.80.60.3-0.3-0.3
Extinction: sum of active levers before priming0.30.30.9-0.5-0.50.9-0.50.90.1-0.2-0.2
Active lever presses in extinction session 61.11.12.4-1.50.10.4-0.00.51.4-1.4-1.4
Delta distance traveled before/after self-admin2.32.53.3-1.21.8-1.51.5-1.41.8-1.6-1.6
Delta ambulatory time before/after self-admin3.13.45.1-2.21.7-1.41.4-1.42.3-2.1-2.1
Time in closed arm before self-admin0.30.30.8-0.40.8-0.70.9-0.70.1-0.2-0.2
Time in closed arm after self-admin1.31.42.10.7-1.11.5-1.11.4-1.21.11.1
Time in open arm before self-admin0.30.41.11.0-0.80.3-0.70.3-0.40.40.4
Time in open arm after self-admin1.11.32.3-0.71.2-0.90.9-0.81.5-1.4-1.4
Sum of active levers in priming session hrs 5-61.01.02.50.31.6-1.21.6-1.2-0.2-0.0-0.0
Time to tail flick, vehicle, before self-admin0.50.51.30.60.4-1.10.7-1.1-0.40.40.4
Time to tail flick, vehicle, after self-admin1.31.43.8-0.8-0.81.9-1.21.90.4-0.6-0.6
Time to tail flick, test, before self-admin1.81.84.0-2.00.20.10.10.11.8-1.9-1.9
Time to tail flick, test, after self-admin0.20.20.9-0.9-0.20.1-0.30.1-0.30.30.3
Delta time to tail flick, vehicle, before/after SA3.23.16.3-1.7-1.02.5-1.62.51.4-1.5-1.5
Delta time to tail flick, test, before/after SA0.50.40.7-0.0-0.70.5-0.80.5-0.70.80.8
Ambulatory time before self-admin0.40.51.00.2-0.90.1-0.50.1-1.00.90.9
Ambulatory time after self-admin2.52.73.7-1.51.4-1.91.5-1.91.6-1.7-1.7
Total heroin consumption0.50.61.8-1.30.30.70.00.70.8-0.7-0.7
Area under the delay curve1.01.12.3-1.0-1.11.5-1.31.5-0.30.30.3
Delay disc. indifference point, 0s delay1.61.72.8-1.6-1.41.6-1.71.70.4-0.6-0.6
Delay disc. indifference point, 16s delay0.60.62.2-1.5-0.30.7-0.50.80.6-0.5-0.5
Delay disc. indifference point, 2s delay0.10.10.7-0.80.2-0.00.0-0.00.1-0.4-0.4
Delay disc. indifference point, 24s delay2.22.23.2-1.1-1.71.8-1.61.8-1.01.31.3
Delay disc. indifference point, 4s delay1.41.53.3-1.3-1.31.8-1.51.8-0.1-0.0-0.0
Delay disc. indifference point, 8s delay0.90.91.40.0-0.71.0-0.81.1-1.11.21.2
Delay discount exponential model param1.11.22.60.91.1-1.61.3-1.60.4-0.4-0.4
Delay discount hyperbolic model param0.80.81.80.90.9-1.31.1-1.30.4-0.4-0.4
Fecal boli incidents, locomotor time 10.20.20.9-0.9-0.2-0.40.1-0.4-0.30.30.3
Change in fecal boli incidents, locomotor task0.10.10.20.3-0.20.4-0.20.4-0.30.50.5
Time >=10cm from walls, locomotor time 12.22.24.7-2.2-0.71.4-1.01.41.6-1.5-1.5
Bouts of movement, locomotor time 10.40.41.10.6-0.71.0-0.61.00.0-0.1-0.1
Total resting periods, locomotor time 10.40.51.40.1-0.61.2-0.71.20.1-0.3-0.3
Rest time, locomotor task time 10.30.30.70.20.8-0.70.8-0.7-0.0-0.1-0.1
Distance moved, locomotor task time 11.11.22.6-0.7-1.61.5-1.61.5-0.30.20.2
Vertical activity count, locomotor time 10.20.20.30.2-0.60.5-0.60.50.1-0.1-0.1
Time >=10cm from walls, locomotor time 21.41.52.9-1.7-1.31.6-1.51.60.2-0.1-0.1
Bouts of movement, locomotor time 21.51.63.21.0-0.80.8-0.70.8-1.81.71.7
Total resting periods, locomotor time 21.92.03.61.2-1.01.0-0.91.0-1.91.81.8
Rest time, locomotor task time 20.91.02.01.4-0.91.4-0.91.4-0.40.50.5
Distance moved, locomotor task time 20.50.52.8-1.7-0.60.3-0.70.30.2-0.4-0.4
Vertical activity count, locomotor time 20.20.20.4-0.5-0.0-0.60.2-0.6-0.60.50.5
Weight adjusted by age0.70.81.8-0.11.3-0.91.0-0.80.6-0.8-0.8
Seeking ratio, delayed vs. immediate footshock0.20.20.80.2-0.90.1-0.60.10.1-0.2-0.2
Locomotion in novel chamber2.02.43.7-0.21.4-1.61.3-1.61.8-1.9-1.9
Locomotion in novel chamber post-restriction1.72.03.2-1.8-0.51.0-1.01.01.7-1.8-1.8
Progressive ratio0.70.81.9-0.1-1.41.2-1.31.20.10.00.0
Food seeking constrained by brief footshock0.80.91.6-0.0-1.11.2-1.31.21.0-0.6-0.6
Seeking ratio, punishment vs. effort0.00.00.10.30.10.3-0.10.30.1-0.0-0.0
Run reversals in cocaine runway, females0.70.71.30.71.0-1.11.2-1.10.3-0.1-0.1
Run reversals in cocaine runway, males0.80.81.11.0-0.61.1-0.81.0-0.60.80.8
Latency to leave start box in cocaine runway1.51.63.5-1.70.1-0.50.1-0.51.5-1.9-1.9
Latency to leave start box in cocaine runway, F0.60.61.7-1.3-0.3-0.5-0.0-0.50.8-1.0-1.0
Latency to leave start box in cocaine runway, M0.90.92.2-0.80.20.3-0.20.31.3-1.5-1.5
Cd content in liver0.30.30.80.3-0.30.3-0.30.3-0.80.90.9
Co content in liver2.02.34.60.51.9-2.22.1-2.1-0.60.50.5
Cu content in liver1.41.73.71.91.1-0.91.2-0.9-1.41.41.4
Fe content in liver2.93.57.82.8-1.00.3-0.60.2-2.42.52.5
K content in liver0.10.10.10.4-0.1-0.0-0.1-0.0-0.30.40.4
Mg content in liver0.40.41.10.7-0.30.1-0.20.1-1.00.80.8
Mn content in liver1.11.32.51.4-0.70.5-0.50.5-1.61.51.5
Na content in liver1.11.12.20.7-1.20.7-1.00.7-1.51.21.2
Rb content in liver0.30.40.8-0.1-0.70.8-0.90.80.3-0.4-0.4
Se content in liver13.015.832.25.4-1.10.0-0.30.0-5.75.65.6
Sr content in liver2.22.03.7-0.11.9-1.91.9-1.90.6-0.7-0.7
Zn content in liver5.56.012.83.1-1.1-0.1-0.4-0.1-3.63.53.5